JUSTIFICATIVA E OBJETIVOS: A disestesia oclusal, também chamada de síndrome da mordida fantasma, é caracterizada por discrepâncias oclusais persistentes e não verificáveis clinicamente. Em 1976 a literatura relatou os dois primeiros casos, porém a abordagem do tratamento tem sido baseada apenas no conhecimento incompleto da etiologia, em que nenhuma das teorias propostas é totalmente explicada em todos os casos disponíveis. O objetivo desta revisão é mostrar as hipóteses sobre a etiologia, diagnóstico e tratamento da disestesia oclusal. MÉTODOS: A revisão da literatura pesquisou as seguintes bases de dados: NCBI/PubMed (National Center for Biotechnology Information) e Scielo (Scientific Electronic Library Online). Na estratégia de busca foram utilizados os seguintes descritores: Disestesia oclusal OR mordida fantasma AND Distúrbios da articulação temporomandibular em português e inglês. Foram encontrados um total de 166 artigos, destes 18 atenderam os critérios de elegibilidade. RESULTADOS: Etiologicamente a disestesia oclusal pode relacionar-se com desordens psiquiátricas, fenômeno do membro fantasma e alterações do input proprioceptivo.  O critério diagnóstico propõe avaliar as queixas de mordida desconfortável por mais de 6 meses, sensação de desconforto ao morder, ausência de discrepância oclusal, sofrimento emocional associado, falhas em vários procedimentos odontológicos. Dentre diversas modalidades de tratamentos, a terapia mais aceita é a medicamentosa com uso de antidepressivos como o milnaciprano. CONCLUSÃO: Em pacientes com queixas oclusais persistentes, o diagnóstico deve considerar a disestesia oclusal. A abordagem terapêutica deve ser realizada por uma equipe interdisciplinar, que inclui além do cirurgião dentista, psiquiatras e psicólogos ​​com experiência nesta área.

BACKGROUND AND OBJECTIVES: Occlusal dysesthesia, also called phantom bite syndrome, is characterized by persistent and clinically unverifiable occlusal discrepancies. In 1976, the literature reported the first two cases, but the treatment approach has been based only on incomplete knowledge of the etiology, in which none of the proposed theories is fully explained in all available cases. The objective of this review is to show hypotheses about the etiology, diagnosis and treatment of occlusal dysesthesia. METHODS: A literature search was performed in the following databases: NCBI/PubMed (National Center for Biotechnology Information) and Scielo (Scientific Electronic Library Online). The following descriptors were used in the search strategy: occlusal dysesthesia OR phantom bite AND temporomandibular joint disorders in Portuguese and English. A total of 166 articles were found, of which 18 met the eligibility criteria. RESULTS: Etiologically, occlusal dysesthesia may be related to psychiatric disorders, phantom limb phenomenon and changes in proprioceptive input. The diagnostic criteria propose to evaluate the complaints of uncomfortable bite for more than 6 months, feeling of discomfort when biting, absence of occlusal discrepancy, associated emotional suffering, and failures in several dental procedures. Among several treatment modalities, the most accepted therapy is medication with the use of antidepressants such as milnacipran. CONCLUSION: In patients with persistent occlusal complaints, the diagnosis should consider occlusal dysesthesia. The therapeutic approach must be carried out by an interdisciplinary team, which includes, in addition to the dental surgeon, psychiatrists and psychologists with experience in this area.

RESUMEN Se presenta el caso clínico de una adolescente de 18 años de edad, quien se accidentó en una motocicleta y fue remitida a la Escuela de Medicina Dental de la ciudad de Torreón, Estado Coahuila de México para la colocación de implantes dentarios. El tratamiento ortodóncico incluyó 2 fases: inicial, con la instalación de una prótesis parcial removible provisional y correctiva, donde se colocó una aparatología fija superior e inferior mediante la técnica de Roth. Con este tratamiento fueron corregidas la maloclusión, la ausencia dentaria y la pérdida ósea. Se logró una transmigración dentaria y a los 22 meses de evolución, la paciente alcanzó una oclusión funcional.

ABSTRACT The case report of an 18 years adolescent is presented, who had an accident in a motorcycle and she was referred to the Dental Medicine School of Torreón city, Coahuila State in Mexico, for the placement of dental implants. The orthodontic treatment included 2 phases: initial, with the installation of a removable, provisional and corrective partial denture, where an upper and lower fixed appliance was placed using the Roth technique. Malocclusion, tooth absence and bone loss were corrected with this treatment. A dental transmigration was achieved and after 22 months of evolution, the patient achieved a functional occlusion.

RESUMEN Introducción: las mal oclusiones dentarias constituyen un problema de salud a nivel mundial como consecuencia de su alta incidencia en deterioro de la estética, la repercusión en la vida social para la persona que lo padece y el elevado costo que conlleva su tratamiento. Objetivo: determinar los factores de riesgo que predisponen a maloclusión en escolares de primer grado de la escuela primaria “Adalberto Pessant”. Métodos: se realizó en estudio observacional, descriptivo y transversal sobre las mal oclusiones dentales en escolares del primer grado de la escuela primaria “Adalberto Pessant” en el período de 2017 a 2019 en el municipio Manzanillo, provincia Granma. De un universo de 65 pacientes, se eligió una muestra de 62 mediante muestreo no probabilístico intencional. Para el análisis de los datos se empleó estadística descriptiva mediante el cálculo de frecuencias absolutas y relativas porcentuales. Resultados: el sexo masculino fue el más frecuente (54,8 %). La mayoría de los niños en la revisión clínica presentaron caries proximales (53,2 %), hábitos bucales deformantes (79,0 %) y presencia de diastemas (56,5 %). Sola en la minoría se encontró espacios de primate (25,8 %). Según la clasificación de Angle sobresalió el tipo I en un 56,5 % y la succión digital fue el hábito bucal más deformante (69,4 %). Conclusiones: dentro de los factores predisponentes a la maloclusión dental se encuentran la presencia de caries proximales y de hábitos bucales deformantes. La promoción de la salud bucal y la prevención de esta entidad son pilares imprescindibles para disminuir su incidencia.

ABSTRACT Introduction: dental malocclusions are a global health problem due to their high incidence of aesthetic deterioration, the impact on the social life of the person suffering from them and the high cost of their treatment. Objective: to determine the risk factors that predispose students to malocclusion in the first grade of the “Adalberto Pessant” Primary School. Methods: this was an observational, descriptive and cross-sectional study on dental malocclusions in students of the first grade of the primary school “Adalberto Pessant” in the period from 2017 to 2019 in the municipality of Manzanillo, in Granma, Cuba. From a universe of 65 patients, a sample of 62 was selected through intentional non-probabilistic sampling. Descriptive statistics were used for data analysis by calculating absolute and relative percentages. Results: males were the most frequent (54,8 %). Most of the children in the clinical review had proximal caries (53,2 %), deforming oral habits (79,0 %) and presence of diastema (56,5 %). Only in the minority were found primate spaces According to Angle's classification, type I stood out by 56,5 % and digital suction was the most deforming oral habit. (69,4 %). Conclusions: Among the predisposing factors to dental malocclusion are the presence of proximal caries and deforming oral habits. The promotion of oral health and the prevention of this entity are essential pillars to reduce its incidence.

ABSTRACT Introduction: Class II malocclusion is one of the anomalies that affect facial aesthetics, which is why it is one of the most frequent in the Orthodontic Consultation. Objective: to design an integrated classification for patients with Class II malocclusion that allows efficient diagnosis and treatment. Methods: a descriptive cross-sectional investigation with a mixed approach was carried out in the Department of Clinical Sciences of the Faculty of Stomatology of the University of Medical Sciences of Villa Clara in the period between 2020 and 2023. We worked with a sample not probabilistic that was made up of seven experts to whom three surveys were administered. The number of experts was determined using criteria based on the binomial probability distribution. The competence of the experts was determined by the competence coefficient, which was calculated according to the expert's opinion about his level of knowledge about the problem and with the sources that allowed him to argue his criteria. Results: the reviewed documentation provided valuable information and the specialists issued different criteria on the classification and diagnosis of Class II malocclusion. The experts established the invariable elements for their classification. Conclusions: the classification of malocclusion was carried out based on a diagnostic taxonomy that included invariable elements in order to achieve more comprehensive and efficient attention to malocclusion.

RESUMEN Introducción: la maloclusión de Clase II es una de las anomalías que afectan la estética facial, por lo que es una de las más frecuentes en la Consulta de Ortodoncia. Objetivo: diseñar una clasificación integrada para pacientes con maloclusión de Clase II que permita el diagnóstico y el tratamiento eficiente. Métodos: se realizó una investigación descriptiva de corte transversal con enfoque mixto en el Departamento de Ciencias Clínicas de la Facultad de Estomatología de la Universidad de Ciencias Médicas de Villa Clara en el período comprendido entre los años 2020 y 2023. Se trabajó con una muestra no probabilística que estuvo constituida por siete expertos a los que se les aplicaron tres encuestas. La determinación del número de expertos se realizó utilizando criterios basados en la distribución binomial de probabilidad. La competencia de los expertos se determinó por el coeficiente de competencia, el que se calculó de acuerdo con la opinión del experto sobre su nivel de conocimiento acerca del problema y con las fuentes que permitieron argumentar sus criterios. Resultados: la documentación revisada aportó información valiosa y los especialistas emitieron diferentes criterios sobre la clasificación y el diagnóstico de la maloclusión de Clase II. Los expertos establecieron los elementos invariables para su clasificación. Conclusiones: se realizó la clasificación de la maloclusión a partir de una taxonomía de diagnóstico que incluyó los elementos invariables con el fin de lograr una atención más integral y eficiente de la maloclusión.

RESUMEN Fundamento la maloclusión de clase II presenta la mayor prevalencia entre las alteraciones dentoesqueléticas. Objetivo: proponer una guía de atención para pacientes con maloclusión de clase II con dentición permanente en crecimiento activo. Métodos: se realizó una investigación de innovación tecnológica de enfoque mixto en el Departamento de Ciencias Clínicas de la Facultad de Estomatología de la Universidad de Ciencias Médicas de Villa Clara, en el periodo comprendido entre los años 2020 y 2023. El universo de estudio estuvo constituido por todos los especialistas de Ortodoncia de la provincia de Villa Clara, Sancti Spíritus y Cienfuegos, a partir del cual se realizó un muestreo no probabilístico intencional por criterios y quedó constituida la muestra por 20 especialistas y siete expertos (especialistas de categoría superior) con criterios de inclusión. Resultados: la documentación revisada aportó información valiosa para determinar el estado actual de la atención de la maloclusión de estudio. Los especialistas emitieron diferentes criterios sobre el diagnóstico y tratamiento de la maloclusión de clase II. Los expertos establecieron los elementos invariables para su clasificación. Finalmente se diseñó una guía de atención para los pacientes con maloclusión de clase II con dentición permanente en crecimiento activo, valorada por los especialistas con la categoría de excelente. Conclusiones: la guía propuesta contiene elementos invariables de diagnóstico y pautas de tratamiento con el fin de lograr una atención más integral y eficiente de la maloclusión.

ABSTRACT Foundation: Class II malocclusion has the highest prevalence among dentoskeletal disorders. Objective: to propose a care guide for patients with class II malocclusion with actively growing permanent dentition. Method: a mixed approach technological innovation research was carried out in the Clinical Sciences Department from the Stomatology Faculty of the Villa Clara Medical Sciences University, from 2020 to 2023. The studied universe was all the Orthodontic specialists in the Villa Clara province, Sancti Spíritus and Cienfuegos, from which an intentional non-probabilistic sampling was carried out by criteria and the sample was made up of 20 specialists and seven experts (higher category specialists) with criteria of inclusion. Results: The reviewed documentation provided valuable information to determine the current state of care for malocclusion under study. Specialists issued different criteria on the diagnosis and treatment of class II malocclusion. The experts established the invariable elements for their classification. Finally, a care guide was designed for patients with class II malocclusion with actively growing permanent dentition, rated by specialists as excellent. Conclusions: the proposed guide contains invariable diagnostic elements and treatment guidelines in order to achieve more comprehensive and efficient malocclusion care.

ABSTRACT Fibrous dysplasia is a benign and progressive bone disease of genetic basis that can affect one or several bones. Its high incidence in the pediatric age served as a basis for it to be previously considered exclusive to this stage; however, there are reports to date that show its development and later growth in the second decade of life. When associated with endocrine imbalances and café-au-lait spots, it is part of the McCune-Albright syndrome. The present case report shows the clinical and radiologic features of the oral-facial region of an adult patient with McCune-Albright syndrome. Lesions in the jaws affect the morphology and cause dysfunction. At the dental level, the changes produced result in malocclusion and structural defects. Radiological studies showed changes with mixed density and ground glass pattern.

RESUMEN La displasia fibrosa es una enfermedad ósea benigna y progresiva, de base genética que puede afectar a uno o varios huesos. Su alta incidencia en la edad pediátrica sirvió de base para que anteriormente fuera considerada exclusiva de esta etapa; sin embargo, a la fecha, existen reportes que evidencian su desarrollo y crecimiento posterior en la segunda década de vida. Cuando está asociada a desequilibrios endocrinos y manchas café con leche, forma parte del síndrome de McCune-Albright. El presente reporte de caso muestra las características clínicas y radiológicas de la región bucofacial de un paciente adulto portador del síndrome de McCune-Albright. Las lesiones en los maxilares afectan la morfología y causan disfunción. A nivel dentario, los cambios producidos se traducen en maloclusión y defectos estructurales. En los estudios radiológicos se observaron cambios con densidad mixta y el patrón de vidrio esmerilado.

RESUMO A displasia fibrosa é uma doença óssea benigna, progressiva e de base genética que pode afetar um ou mais ossos. A sua elevada incidência no grupo etário pediátrico foi a base para que anteriormente fosse considerada exclusiva desta fase; no entanto, existem relatos até à data do seu desenvolvimento e crescimento mais tardio na segunda década de vida. Quando associada a desequilíbrios endócrinos e manchas café-com-leite, faz parte da síndrome de McCune-Albright. Este relato de caso mostra as características clínicas e radiológicas da região bucofacial de um paciente adulto com síndrome de McCune-Albright. As lesões nos maxilares afetam a morfologia e provocam disfunções. A nível dentário, as alterações produzidas resultam em má oclusão e defeitos estruturais. Nos estudos radiológicos, foram observadas alterações com densidade mista e padrão de vidro despolido.

Abstract This study aimed to estimate the prevalence and extent of bleeding on probing and calculus in 12-year-old schoolchildren of Quito, Ecuador, and evaluate the associated factors. We conducted an epidemiological survey with a representative sample of 1,100 12-year-old schoolchildren from public schools in the urban area of Quito, Ecuador. We assessed the periodontal health using the Community Periodontal Index (CPI). The prevalence and extent of the periodontal condition was based on the presence of at least one site with bleeding on probing (BOP), and the presence of dental calculus was also evaluated. We used univariate and multiple multilevel Poisson regression analyses to verify the association between the independent variables and the number of sextants with BOP and calculus. The prevalence of BOP and calculus was 92% and 69.9%, respectively. The adjusted mean of the affected sextants was 4.3 and 2.2 for BOP and calculus, respectively. The mother’s schooling and malocclusion were associated with the number of sextants with bleeding. The mother’s schooling and dental caries experience were associated with calculus. Gingival bleeding and the presence of dental calculus are highly prevalent in 12-year-old schoolchildren from Quito. Gingival bleeding is associated with maternal education and malocclusion, and dental calculus is associated with maternal education and dental caries. 12yearold yearold 12 year old Quito Ecuador factors 1100 1 100 1,10 CPI. CPI . (CPI) BOP, , (BOP) evaluated 92 699 69 9 69.9% respectively 43 4 3 4. 22 2 2. mothers mother s 110 10 1,1 (CPI (BOP 6 69.9 11 1, 69.

ABSTRACT Objective: This study aimed to evaluate occlusion development after premature loss or extraction of deciduous anterior teeth, by means of a prospective cohort study. Methods: Fifteen infants and children aged 1 to 5 years old were longitudinally assessed (with loss or extraction of deciduous anterior teeth [n = 9], and without tooth losses [n = 6]). Photographs and dental casts at the baseline and after 24 months of follow-up were performed. Dental casts were scanned, and linear measurements were made on the digitalized models (missing tooth space, arch perimeter, arch length, arch width, intercanine length and intercanine width). The t-test was used for groups comparisons (α = 0.05). Results: Individuals’ mean age at baseline was 2.93 (± 1.18) years. No statistically significant differences were observed in the missing tooth space in the group with tooth loss during the 24 months of follow-up (p > 0.05). Arch perimeter, arch length, arch width, intercanine length and intercanine width did not show differences between the groups (p > 0.05). Qualitative photographic evaluation revealed other changes in the dental arches and occlusion, such as exfoliation and eruption of deciduous teeth, eruption of permanent teeth, self-correction or establishment of malocclusion, among others. Conclusion: The results suggest that the premature loss of deciduous anterior teeth does not affect the perimeter, length and width of the dental arches; however, other alterations that lead to malocclusion could be established. Objective Methods n 9, 9 , 9] 6. 6 . 6]) 2 followup follow up performed scanned perimeter width. width) ttest t test α 0.05. 005 0.05 0 05 0.05) Results Individuals 293 93 2.9 ± ( 1.18 118 18 p selfcorrection self correction others Conclusion however established 6] 00 0.0 29 2. 1.1 11 0. 1.

RESUMO Objetivo: Este estudo teve como objetivo avaliar o desenvolvimento da oclusão após perda prematura ou extração de dentes decíduos anteriores, por meio de um estudo de coorte prospectivo. Métodos: Quinze bebês e crianças de 1 a 5 anos foram avaliados longitudinalmente (com perda ou extração de dentes anteriores decíduos [n = 9] e sem perdas dentárias [n = 6]). Foram realizadas fotografias e modelos dentais no início e após 24 meses de acompanhamento. Os modelos dentários foram escaneados e medidas lineares foram feitas nos modelos digitalizados (espaço dentário perdido, perímetro da arcada, comprimento da arcada, largura da arcada, comprimento intercaninos e largura intercaninos). O teste t foi utilizado para comparações entre grupos (α = 0,05). Resultados: A média de idade dos indivíduos no início do estudo foi de 2,93 (± 1,18) anos. Não foram observadas diferenças estatisticamente significativas no espaço dentário perdido no grupo com perda dentária durante os 24 meses de acompanhamento (p > 0,05). O perímetro da arcada, comprimento da arcada, largura da arcada, comprimento intercaninos e largura intercaninos não apresentaram diferenças entre os grupos (p> 0,05). A avaliação fotográfica qualitativa revelou alterações nas arcadas dentárias e na oclusão, como: esfoliação e erupção de dentes decíduos, erupção de dentes permanentes, autocorreção ou estabelecimento de má oclusão, entre outras. Conclusão: Os resultados sugerem que a perda prematura de dentes anteriores decíduos não afeta o perímetro, comprimento e largura das arcadas dentárias; entretanto, outras alterações que levam à má oclusão poderiam ser estabelecidas. Objetivo prospectivo Métodos n 9 6. 6 . 6]) 2 arcada intercaninos. intercaninos) α 0,05. 005 0,05 0 05 0,05) Resultados 293 93 2,9 ± ( 1,18 118 18 p p> permanentes Conclusão entretanto estabelecidas 6] 00 0,0 29 2, 1,1 11 0, 1,

ABSTRACT Objective: To assess the impact of Molar Incisor Hypomineralization (MIH) and confounding factors on oral health-related quality of life (OHRQoL) according to the perception of 8 to 10-year-old children and their parents/caregivers. Material and Methods: A cross-sectional study including 403 students aged 8-10 years was carried out, in which OHRQoL was measured using the Child Perceptions Questionnaire administered to both children and parents/caregivers. The diagnosis of MIH was performed according to the previously proposed index. Dental caries experience, malocclusion, and sociodemographic factors were evaluated as confounders. Cluster analysis and Poisson regression with robust variance (p<0.05) were performed. Results: The prevalence of MIH was 13.4%. Parents/caregivers of children with MIH in incisors showed a higher impact prevalence in the emotional well-being domain (PR=1.92; 95%CI=1.16-3.19). Children with hypoplasia had a higher prevalence of negative impact on OHRQoL in the oral symptoms domain (PR=1.51; 95%CI=1.03-2.23). According to the perception of parents/caregivers, dental caries experience had a negative impact on the quality of life of students in the emotional well-being domain (PR=4.19; 95%CI=1.06-16.49) and in the total questionnaire score (PR=3.21; 95%CI=1.06-9.71). Conclusion: According to the perception of parents/caregivers, children with MIH in incisors showed a greater impact on OHRQoL. Additionally, the presence of hypoplasia affected the self-perception of OHRQoL in children, and caries experience influenced the OHRQoL of children, as perceived by parents/caregivers. Objective (MIH healthrelated health related (OHRQoL 10yearold yearold 10 year old parentscaregivers parents caregivers parents/caregivers Methods crosssectional cross sectional 40 810 8-1 out index malocclusion confounders p<0.05 p005 p 0 05 (p<0.05 Results 134 13 4 13.4% Parentscaregivers Parents wellbeing well being PR=1.92 PR192 PR 1 92 (PR=1.92 95%CI=1.163.19. 95CI116319 CI 95%CI=1.16 3.19 . 95 16 3 19 95%CI=1.16-3.19) PR=1.51 PR151 51 (PR=1.51 95%CI=1.032.23. 95CI103223 95%CI=1.03 2.23 03 2 23 95%CI=1.03-2.23) PR=4.19 PR419 (PR=4.19 95%CI=1.0616.49 95CI1061649 95%CI=1.06 16.49 06 49 95%CI=1.06-16.49 PR=3.21 PR321 21 (PR=3.21 95%CI=1.069.71. 95CI106971 9.71 9 71 95%CI=1.06-9.71) Conclusion Additionally selfperception self 81 8- p<0.0 p00 (p<0.0 13.4 PR=1.9 PR19 (PR=1.9 163 95%CI=1.163.19 95CI11631 95CI116 95%CI=1.1 319 3.1 95%CI=1.16-3.19 PR=1.5 PR15 5 (PR=1.5 032 95%CI=1.032.23 95CI10322 95CI103 95%CI=1.0 223 2.2 95%CI=1.03-2.23 PR=4.1 PR41 (PR=4.1 0616 95%CI=1.0616.4 95CI106164 95CI106 1649 16.4 95%CI=1.06-16.4 PR=3.2 PR32 (PR=3.2 069 95%CI=1.069.71 95CI10697 971 9.7 7 95%CI=1.06-9.71 p<0. p0 (p<0. 13. PR=1. PR1 (PR=1. 95%CI=1.163.1 95CI1163 95CI11 95%CI=1. 31 3. 95%CI=1.16-3.1 95%CI=1.032.2 95CI1032 95CI10 22 2. 95%CI=1.03-2.2 PR=4. PR4 (PR=4. 061 95%CI=1.0616. 95CI10616 164 16. 95%CI=1.06-16. PR=3. PR3 (PR=3. 95%CI=1.069.7 95CI1069 97 9. 95%CI=1.06-9.7 p<0 (p<0 PR=1 (PR=1 95%CI=1.163. 95CI1 95%CI=1 95%CI=1.16-3. 95%CI=1.032. 95%CI=1.03-2. PR=4 (PR=4 95%CI=1.0616 95CI1061 95%CI=1.06-16 PR=3 (PR=3 95%CI=1.069. 95%CI=1.06-9. p< (p< PR= (PR= 95%CI=1.163 95CI 95%CI= 95%CI=1.16-3 95%CI=1.032 95%CI=1.03-2 95%CI=1.061 95%CI=1.06-1 95%CI=1.069 95%CI=1.06-9 (p (PR 95%CI 95%CI=1.16- 95%CI=1.03- 95%CI=1.06-

ABSTRACT Objective: The aim of this study was to evaluate the extent to which orthodontic treatment need is perceived by the patients and by the orthodontist, as well as the possible impacts on the OHRQoL (Oral Health-Related Quality of Life) over the course of conventional orthodontic treatment in adolescent patients. Methods: The sample consisted of 55 adolescents. The perception of patients and orthodontists relative to the malocclusion was evaluated by the IOTN (Index of Orthodontic Treatment Need). The OHRQoL was evaluated by the Child-OIDP (Child-Oral Impacts on Daily Performances) questionnaire before the conventional orthodontic appliance was bonded (T0); and at the following time intervals: after one week (T1), one month (T2), three months (T3), six months (T4), and after the end of orthodontic treatment (T5). Results: Adolescents who had large orthodontic treatment needs had a poor OHRQoL, according to their self-perception (p=0.003) and according to the orthodontist’s perception (p<0.001), when compared with patients with small and moderate needs. There was statistically significant difference in the OHRQoL between the time intervals T0 and T1 (p=0.021), T2 and T3 (p<0.001), T3 and T4 (p=0.033), and T0 and T5 (p<0.002). At the end of treatment, all evaluated participants reported an improvement in OHRQoL. Conclusions: It was concluded that adolescents and orthodontists agreed with regard to the perception of orthodontic treatment need. In the first week and in the first month of orthodontic treatment, there was a negative impact on the OHRQoL. After three months, an improvement of OHRQoL was detected, which has progressed over time. Objective orthodontist Oral HealthRelated Health Related Life Methods 5 Index Need. Need . Need) ChildOIDP Child OIDP ChildOral Performances T (T0) T1, , (T1) T2, (T2) T3, (T3) T4, (T4) T5. (T5) Results selfperception self p=0.003 p0003 p 0 003 (p=0.003 s p<0.001, p0001 p<0.001 001 (p<0.001) p=0.021, p0021 p=0.021 021 (p=0.021) p=0.033, p0033 p=0.033 033 (p=0.033) p<0.002. p0002 p<0.002 002 (p<0.002) Conclusions detected (T0 (T1 (T2 (T3 (T4 (T5 p=0.00 p000 00 (p=0.00 p<0.00 (p<0.001 p002 p=0.02 02 (p=0.021 p003 p=0.03 03 (p=0.033 (p<0.002 (T p=0.0 p00 (p=0.0 p<0.0 (p<0.00 (p=0.02 (p=0.03 p=0. p0 (p=0. p<0. (p<0.0 p=0 (p=0 p<0 (p<0. p= (p= p< (p<0 (p (p<

RESUMO Objetivo: O objetivo deste estudo foi avaliar o quanto a necessidade de tratamento ortodôntico é percebida pelos pacientes e pelo ortodontista, bem como os possíveis impactos na Qualidade de Vida Relacionada à Saúde Bucal (QVRSB) ao longo do tratamento ortodôntico convencional em pacientes adolescentes. Métodos: A amostra foi composta por 55 adolescentes. A percepção dos pacientes e ortodontistas em relação à má oclusão foi avaliada pelo Índice de Necessidade de Tratamento Ortodôntico (IOTN). A QVRSB foi avaliada pelo questionário Child-OIDP (Child-Oral Impacts on Daily Performances) antes da colagem do aparelho ortodôntico convencional (T0); e nos seguintes intervalos de tempo: após uma semana (T1), um mês (T2), três meses (T3), seis meses (T4) e após o término do tratamento ortodôntico (T5). Resultados: Adolescentes que apresentavam grandes necessidades de tratamento ortodôntico apresentaram baixa QVRSB, segundo sua autopercepção (p=0,003) e segundo a percepção do ortodontista (p<0,001), quando comparados com pacientes com necessidades pequenas e moderadas . Houve diferença estatisticamente significativa na QVRSB entre os intervalos de tempo T0 e T1 (p=0,021), T2 e T3 (p<0,001), T3 e T4 (p=0,033) e T0 e T 5 (p<0,00 2 ). Ao final do tratamento, todos os participantes avaliados relataram melhora na QVRSB. Conclusões: Concluiu-se que adolescentes e ortodontistas concordaram quanto à percepção da necessidade de tratamento ortodôntico. Na primeira semana e no primeiro mês de tratamento ortodôntico, houve impacto negativo na QVRSB. Após três meses, foi detectada uma melhora na QVRSB, que progrediu ao longo do tempo. Objetivo (QVRSB Métodos IOTN. IOTN (IOTN) ChildOIDP Child OIDP ChildOral Oral Performances (T0) T1, , (T1) T2, (T2) T3, (T3) (T4 T5. T5 (T5) Resultados p=0,003 p0003 p 0 003 (p=0,003 p<0,001, p0001 p<0,001 001 (p<0,001) p=0,021, p0021 p=0,021 021 (p=0,021) p=0,033 p0033 033 (p=0,033 p<0,00 p000 00 (p<0,0 ) Conclusões Concluiuse Concluiu se (IOTN (T0 (T1 (T2 (T3 (T (T5 p=0,00 (p=0,00 (p<0,001 p002 p=0,02 02 (p=0,021 p=0,03 p003 03 (p=0,03 p<0,0 p00 (p<0, p=0,0 (p=0,0 (p=0,02 p<0, p0 (p<0 p=0, (p=0, p<0 (p< p=0 (p=0 p< (p p= (p=

ABSTRACT Objective: To assess the methodological quality and characteristics of systematic reviews (SRs) of interventional studies in orthodontics and assess how the certainty of the evidence is reported using the GRADE approach. Material and Methods: Six electronic databases were searched, followed by a hand search of the reference lists of eligible studies (PROSPERO #CRD42020180852). The required study design was randomized and nonrandomized studies of interventions published between January 2019 and May 2020. The Assessing the Methodological Quality of Systematic Reviews (AMSTAR 2) tool was used for the quality appraisal of the included SRs. Paired reviewers independently screened the studies, extracted data, and appraised the methodological quality. Results: The study included 46 SRs; 19.5% had moderate to high methodological quality, and the remaining had low to critically low methodological quality. Fifty-four percent of the reviews assessed the certainty of evidence using the GRADE approach, and 34.8% followed all GRADE criteria. Conclusion: Most reviews had a good judgment of the AMSTAR2 items, although some critical items contributed to decreased overall quality. Half of the reviews used the GRADE approach to assess the certainty of the evidence, and this approach should be included in future systematic reviews of interventions. Objective SRs (SRs Methods searched PROSPERO #CRD42020180852. CRD42020180852 CRD #CRD42020180852 . #CRD42020180852) 201 2020 AMSTAR 2 data Results 4 195 19 5 19.5 Fiftyfour Fifty four 348 34 8 34.8 criteria Conclusion CRD4202018085 #CRD4202018085 20 202 1 19. 3 34. CRD420201808 #CRD420201808 CRD42020180 #CRD42020180 CRD4202018 #CRD4202018 CRD420201 #CRD420201 CRD42020 #CRD42020 CRD4202 #CRD4202 CRD420 #CRD420 CRD42 #CRD42 CRD4 #CRD4 #CRD

ABSTRACT Objective: To estimate the serum levels of non-radiologic biomarkers, Insulin-like Growth Factor-1 (IGF-1), and Insulin-like Growth Factor Binding Protein-3 (IGFBP-3) to potentially identify the pubertal growth spurt in skeletal Class II malocclusion subjects. Material and Methods: Eighty subjects (M-38, F-42) with skeletal Class II malocclusion in the age range of 11-18 years were recruited for the cross-sectional study. Human serum IGF-1 and IGFBP-3 were quantitatively assessed by enzyme-linked immunosorbent assay, and the cervical stage (CS) was evaluated from a lateral cephalogram. Results: Gender-wise comparison of the mean serum IGF-1 levels revealed that the initial peak was detected at CS2 in both genders, [males (87.87 ng/mL), females (78.49 ng/mL)]. However, there was a cognizable difference in the second peak of the mean serum IGF-1 levels between males (CS5, 68.58 ng/mL) and females (CS4, 74.63 ng/mL). Mean IGFBP-3 serum levels in male subjects were high in CS4 (47.24 ng/mL) with a further spike in CS6 (50.54 ng/mL), and in female subjects, it was found to be highest in CS3 (51.95 ng/mL) and then in CS5 (49.68 ng/mL). Conclusion: Mean IGF-1 levels exhibited both sexes' prepubertal and late pubertal spikes. Mean IGFBP-3 levels revealed a pubertal and a late pubertal spike in both sexes, with an earlier growth trend observed specific to females compared to males. Objective nonradiologic non radiologic biomarkers Insulinlike Insulin like Factor1 1 Factor- IGF1, IGF1 IGF , (IGF-1) Protein3 Protein 3 Protein- IGFBP3 IGFBP (IGFBP-3 Methods M38, M38 M 38, 38 (M-38 F42 F 42 F-42 1118 11 18 11-1 crosssectional cross sectional study IGF- IGFBP- enzymelinked enzyme linked assay CS (CS cephalogram Results Genderwise Gender wise genders 87.87 8787 87 (87.8 ng/mL, ngmL ng/mL ng mL 78.49 7849 78 49 (78.4 ng/mL. . ng/mL)] However CS5, (CS5 6858 68 58 68.5 CS4, (CS4 7463 74 63 74.6 47.24 4724 47 24 (47.2 50.54 5054 50 54 (50.5 51.95 5195 51 95 (51.9 49.68 4968 (49.6 Conclusion sexes spikes (IGF-1 (IGFBP- M3 (M-3 F4 4 F-4 111 11- 87.8 878 8 (87. 78.4 784 7 (78. 685 6 5 68. 746 74. 47.2 472 2 (47. 50.5 505 (50. 51.9 519 9 (51. 49.6 496 (49. (IGF- (IGFBP (M- F- 87. (87 78. (78 47. (47 50. (50 51. (51 49. (49 (IGF (M (8 (7 (4 (5 (

ABSTRACT Objective: This retrospective study aimed to assess the predictability of Invisalign® aligners regarding rotational, mesio-distal and buccal-lingual tip movements. Methods: Two materials were included in the analysis - EX30, used until 2013; and SmartTrack, in current use. The study comprised 56 adult patients treated with Invisalign Comprehensive. Data sample were assessed on three sets of digital models; model 1 - initial, model 2 - predicted, and model 3 - achieved. Sixty reference points were marked in each dental arch, and two reference planes assisted the superimposition. The degree of rotation, mesio-distal and buccal-lingual tip was obtained via trigonometric calculations, through a previously published validated method. The accuracy of outcomes was compared according to the types of tooth movement and teeth groups,and the influence of predetermined variables on movement accuracy was also investigated. Results: Rotation and mesio-distal tip did not present any significant difference when comparing EX30 and SmartTrack groups. Only buccal-lingual tip presented a significant difference, incisor and canine groups treated with EX30 aligners presented an increase in accuracy (p= 0.007 and p = 0.007, respectively). For each additional degree planned for rotation movements, there was an increase of 0.35° in the discrepancy, and an increase of 0.40° and 0.41° for mesio-distal and buccal-lingual tip, respectively. EX30 and SmartTrack discrepancies were compared by multilevel linear regression. Conclusion: EX30 aligners reached higher accuracy for buccal-lingual tip in anterior teeth. However, for rotation and mesio-distal tip, SmartTrack and EX30 are similarly accurate. The total amount of planned movement has a significant impact on accuracy rates, with a decrease in accuracy for every additional degree. Objective rotational mesiodistal mesio distal buccallingual buccal lingual movements Methods EX 2013 use 5 Comprehensive models initial predicted achieved arch superimposition calculations method groupsand investigated Results EX3 p= (p 0007 0 007 0.00 respectively . respectively) 035 35 0.35 discrepancy 040 40 0.40 041 41 0.41 regression Conclusion However accurate rates 201 000 00 0.0 03 0.3 04 4 0.4 20 0.

RESUMO Objetivo: Esse estudo retrospectivo teve como objetivo aferir a previsibilidade dos alinhadores Invisalign em relação aos movimentos de rotação e inclinações mesiodistal e vestibulolingual. Material e Métodos: Foram incluídos dois materiais nessa análise: EX30®, utilizado até 2013; e SmartTrack®, atualmente em uso. Esse estudo avaliou 56 pacientes tratados com Invisalign Comprehensive. Os dados foram avaliados em três pares de modelos digitais; modelo 1 - inicial, modelo 2 - planejado, e modelo 3 - alcançado. Foram marcados 60 pontos de referência em cada arcada, sendo a sobreposição realizada com auxílio de planos de referência. O grau de rotação e inclinações mesiodistal e vestibulolingual foi obtido por cálculos de trigonometria, usando um método validado publicado anteriormente. Os resultados foram comparados de acordo com os tipos de movimento dentário e grupos de dentes, também foi investigada a influência de variáveis predeterminadas na confiabilidade dos movimentos. Resultados: Os movimentos de rotação e inclinação mesiodistal não apresentaram diferença estatística, quando comparados os grupos EX30® e SmartTrack®. Somente a inclinação vestibulolingual apresentou diferença estatisticamente significativa, sendo que os grupos de incisivos e caninos tratados com alinhadores EX30® apresentaram um aumento na previsibilidade(p= 0,007 e p= 0,007, respectivamente). Para cada grau adicional planejado para movimento de rotação, ocorreu um aumento de 0,35° na discrepância, e aumentos de 0,40° e 0,41° para as inclinações mesiodistal e vestibulolingual, respectivamente. As discrepâncias entre EX30® e SmartTrack® foram comparadas por regressão linear multinível. Conclusão: Os alinhadores EX30® alcançaram maior previsibilidade para a inclinação vestibulolingual em dentes anteriores. No entanto, para rotação e inclinação mesiodistal, SmartTrack® e EX30® apresentaram previsibilidade similar. A quantidade total de movimento planejado apresenta influência significativa nas taxas de previsibilidade, com diminuição na acurácia para cada grau adicional. Objetivo Métodos análise EX30 EX 2013 SmartTrack uso 5 Comprehensive digitais inicial alcançado 6 arcada trigonometria anteriormente Resultados estatística previsibilidadep= previsibilidadep p previsibilidade(p 0007 0 007 0,00 respectivamente . respectivamente) 035 35 0,35 discrepância 040 40 0,40 041 41 0,41 multinível Conclusão anteriores entanto similar EX3 201 000 00 0,0 03 0,3 04 4 0,4 20 0,

Abstract The aim of this study was to evaluate the convergence between the domains of the Autoquestionnaire Qualité de Vie Enfant image (AUQUEI) and the Child Perceptions Questionnaire (CPQ8-10) in the mixed dentition. A sample of 676 children aged 8 to 10 years responded to the health-related quality of life (HRQoL) and oral health-related quality of life (OHRQoL) questionnaires using the AUQUEI and the CPQ8-10, respectively. Clinical (dental caries and malocclusion) and socioeconomic variables were assessed. The validity of convergence between scores (total and per domain) of the two instruments was assessed by Spearman correlation analysis, considering that non-zero coefficient values represented a correlation between scores. The median was calculated to compare the scores of each questionnaire relative to the variables, and the nonparametric Mann-Whitney test was applied to determine statistically significant differences between the categories. A weak significant correlation (between 0.30 and 0.50) was observed between the domains and the total scores of instruments (p < 0.05), except for the leisure domain (p > 0.05). Participants with a lower family income had worse HRQoL (p < 0.05), and those with caries and malocclusion experience had worse OHRQoL (p < 0.05). In conclusion, the AUQUEI and CPQ8-10 instruments showed a weak correlation. Income and clinical variables had a negative impact on the AUQUEI and CPQ8-10, respectively. (AUQUEI CPQ810 CPQ CPQ8 (CPQ8-10 dentition 67 1 healthrelated health related (HRQoL (OHRQoL CPQ810, 10, respectively dental analysis nonzero non zero MannWhitney Mann Whitney categories 030 0 30 0.3 0.50 050 50 p 0.05, 005 0.05 , 05 0.05) 0.05. . conclusion CPQ8-1 CPQ81 (CPQ8-1 6 03 3 0. 0.5 5 00 0.0 CPQ8- (CPQ8- (CPQ8 (CPQ

Abstract The present study aimed to investigate the prevalence of dissatisfaction with dental appearance among 24-year-old Brazilian adults and the associated factors in life course. A subsample (n = 720) of the 1982 Pelotas Birth Cohort in southern Brazil was investigated at the ages of 15 and 24 years using clinical (caries and periodontal) examinations and interviews. The outcome was dissatisfaction with dental appearance at the age of 24 years. Covariate variables included socioeconomic factors, oral health, and dissatisfaction with general appearance collected during different periods of life. Poisson regression models with robust variance were applied. The prevalence of dissatisfaction with dental appearance was 43.5% (95%CI: 39.8–47.1). Individuals with downward income mobility (PR = 1.22, 95%CI: 1.07–1.79) and those always poor (PR = 1.21, 95%CI: 1.00–1.57) presented a higher prevalence of dissatisfaction with their dental appearance even after oral health variables and dissatisfaction with general appearance were controlled for. Moderate/severe malocclusion at 15 years (PR = 1.34, 95%CI: 1.13–1.59), highest experience of untreated dental caries at 24 years (PR = 1.82, 95%CI: 1.46–2.27), and dental pain experience at 24 years (PR = 1.29, 95%CI: 1.22–1.75) were associated with the outcome. Also, the prevalence of dissatisfaction with dental appearance was 20% higher (PR = 1.20, 95%CI: 1.01–1.43) among those dissatisfied with their general appearance. Our findings demonstrated a high prevalence of dissatisfaction with dental appearance among young adults. Lifetime economic disadvantage and dental problems (malocclusion at 15 years, untreated dental caries at 24 years, and dental pain at 24 years) were associated with dissatisfaction with dental appearance among young adults. 24yearold yearold year old course n 720 198 1 2 periodontal interviews applied 435 43 5 43.5 95%CI 95CI CI 95 (95%CI 39.8–47.1. 398471 39.8–47.1 . 39 8 47 39.8–47.1) PR 122 22 1.22 1.07–1.79 107179 07 79 121 21 1.21 1.00–1.57 100157 00 57 for Moderatesevere Moderate severe 134 34 1.34 1.13–1.59, 113159 1.13–1.59 , 13 59 1.13–1.59) 182 82 1.82 1.46–2.27, 146227 1.46–2.27 46 27 1.46–2.27) 129 29 1.29 1.22–1.75 122175 75 Also 20 120 1.20 1.01–1.43 101143 01 72 19 4 43. 9 39847 39.8–47. 3 12 1.2 1.07–1.7 10717 0 7 1.00–1.5 10015 1.3 11315 1.13–1.5 18 1.8 14622 1.46–2.2 1.22–1.7 12217 1.01–1.4 10114 3984 39.8–47 1. 1.07–1. 1071 1.00–1. 1001 1131 1.13–1. 1462 1.46–2. 1.22–1. 1221 1.01–1. 1011 398 39.8–4 1.07–1 107 1.00–1 100 113 1.13–1 146 1.46–2 1.22–1 1.01–1 101 39.8– 1.07– 10 1.00– 11 1.13– 14 1.46– 1.22– 1.01– 39.8 1.07 1.00 1.13 1.46 1.01 39. 1.0 1.1 1.4