Resumo O Distrito Industrial de Marabá (DIM) é um local vinculado à transformação e ao beneficiamento de recursos sob uma ótica de agregação de valor ao minério de ferro de Carajás-PA. Porém, indústrias locais promoveram grande transformação espacial com o emprego de técnicas e tecnologias arcaicas e poluentes que, após aumento nos custos e alteração nos preços internacionais, tiveram as áreas abandonadas, indicando um processo de campo marrom (brownfield) em formação no DIM e áreas conexas. Seguiu-se um processo de transumância, acompanhado de ciclos de retração e concentração econômica. Verifica-se uma condição de periferia mineroindustrial na implantação e concepção do DIM, bem como a formação como um campo marrom, inclusive com repercussões espaciais, econômicas, demográficas e ambientais. (DIM CarajásPA. CarajásPA Carajás PA. PA Carajás-PA Porém que internacionais abandonadas brownfield (brownfield conexas Seguiuse Seguiu se transumância econômica Verificase Verifica espaciais econômicas ambientais

Abstract The Marabá Industrial District (MID) is a place connected with the transformation and processing of resources from the perspective of adding value to the iron ore of Carajás (State of Pará). However, local industries have promoted a great spatial transformation, using archaic and polluting techniques and technologies. After an increase in costs and changes in international prices, the areas of these industries were abandoned, indicating a brownfield process under formation in the MID and related areas. This was followed by a process of transhumance, accompanied by cycles of economic contraction and concentration. A mining-industrial periphery condition is perceived in the implementation and conception of the MID, as well as its formation as a brownfield, with spatial, economic, demographic, and environmental repercussions. (MID State Pará. Pará . Pará) However technologies prices abandoned transhumance concentration miningindustrial mining industrial demographic repercussions

ABSTRACT Purpose: To characterize the extracellular vesicle protein cargo in the aqueous humor and plasma of patients with ocular toxoplasmosis. Methods: Aqueous humor and plasma were collected from six patients with active ocular toxoplasmosis and six patients with cataract. Extracellular vesicles were isolated, and western blotting and mass spectrometry were performed for protein analysis. Results: All plasma samples from patients with ocular toxoplasmosis and cataract were positive for the tetraspanins CD63 and TSG101. However, the aqueous humor from patients with ocular toxoplasmosis was positive only for CD63. Sixty-seven new unreported proteins were identified in the aqueous humor and plasma of patients with the ocular toxoplasmosis and cataract. Of the 67 proteins, 10 and 7 were found only in the cataract and ocular toxoplasmosis groups, respectively. In general, these proteins were involved in immune system activation and retina homeostasis and were related to infections and retina-associated diseases. Conclusion: The distinct protein signatures between ocular toxoplasmosis and cataract may be helpful in the differential diagnosis of ocular toxoplasmosis. However, more studies are needed to better understand the role of these proteins in the pathogenesis of ocular toxoplasmosis. Purpose Methods isolated analysis Results CD CD6 TSG101 TSG However Sixtyseven Sixty seven 6 1 groups respectively general retinaassociated associated diseases Conclusion TSG10 TSG1

RESUMO Kalanchoe daigremontiana é uma espécie ornamental de propagação obrigatoriamente assexuada. Entretanto, nenhum estudo in vitro foi realizado para avaliar a relação entre mudanças no ambiente de cultivo e variações genéticas de K. daigremontiana. Portanto, o objetivo deste estudo foi estabelecer a melhor concentração de sais no meio Murashige & Skoog (MS) e a concentração de sacarose no meio de cultura, além da qualidade da luz, no desenvolvimento de plântulas de explantes foliares de K. daigremontiana. Além disso, realizamos uma avaliação genética das plântulas resultantes para estudar alterações fenotípicas que poderiam ser atribuídas à variação somaclonal utilizando marcadores da Amplificação Aleatória de DNA polimórfico (RAPD). Para tanto, explantes foliares de K. daigremontiana foram desinfestados e inoculados em diferentes concentrações de sais do meio MS (25, 50 ou 100%), sem sacarose. As culturas foram transferidas para sala de crescimento e submetidas a três condições de luz (branca, azul e vermelha) com fotoperíodo de 16 horas, mais a ausência de luz, sob temperatura de 27 ± 1 °C. Os explantes também foram inoculados em 25% das concentrações de sais do meio MS, suplementado com diferentes concentrações de sacarose (controle - sem sacarose; 1,5; 3,0; 4,5 e 6,0%). Os explantes foliares de K. daigremontiana desenvolveram-se melhor sob luz branca e em qualquer uma das concentrações de sal do meio MS. Meio de cultura isento de sacarose pode ser utilizado e nenhuma variação no perfil genético das plântulas foi observada em comparação com as plantas-mãe nas condições de cultura testadas. assexuada Entretanto K Portanto (MS disso RAPD. RAPD . (RAPD) tanto 25, 25 (25 5 100%, 100 100% , 100%) branca, (branca vermelha horas 2 C °C controle 1,5 15 3,0 30 3 0 45 4 4, 6,0%. 60 6,0% 6 6,0%) desenvolveramse desenvolveram se plantasmãe plantas mãe testadas (RAPD (2 10 1, 3, 6,0 ( 6,

ABSTRACT Kalanchoe daigremontiana is an ornamental species propagated exclusively asexually. However, no in vitro studies have been conducted to assess the relationship between changes in the culture environment and genetic variations of K. daigremontiana. Therefore, this study aimed to determine the optimal concentration of salts in the Murashige & Skoog (MS) medium and the optimal concentration of sucrose in the culture medium, in addition to the quality of light, in the development of in vitro plantlets from leaf explants of K. daigremontiana. Additionally, a genetic evaluation of the resulting plantlets was conducted to study phenotypic changes that could be attributed to somaclonal variation using Random Amplified Polymorphic DNA (RAPD) markers. For this purpose, leaf explants of K. daigremontiana were disinfected and inoculated in different salt concentrations (25, 50, and 100%) of MS medium without sucrose. The cultures were transferred to a growth chamber and subjected to three light conditions (white, blue, and red) with a 16-hour photoperiod, plus the absence of light, at a temperature of 27 ± 1 °C. Explants were also inoculated in 50% salt concentrations of MS medium supplemented with various concentrations of sucrose (control - without sucrose, 1.5, 3.0, 4.5, and 6.0%). K. daigremontiana leaf explants showed optimal development under white light and in any MS medium salt concentrations. A sucrose-free culture medium was viable, and no genetic variation was observed in the plantlets compared to the parent plants under the tested conditions. asexually However K Therefore (MS Additionally RAPD (RAPD markers purpose 25, 25 (25 50 100% 100 white, (white blue red 16hour hour 16 photoperiod 2 C °C control 15 5 1.5 30 3 0 3.0 45 4 4.5 6.0%. 60 6.0% . 6 6.0%) sucrosefree free viable (2 10 1. 3. 4. 6.0 ( 6.

Résumé Les progrès méthodologiques de la science politique au cours des trois dernières décennies ont généré d’importants changements épistémologiques, dont les effets affectent la portée des théories consolidées. Parmi ces changements, je soutiens que l’évaluation causale de l’impact des institutions sur le comportement politique se heurte à des défis qui ont été négligés lorsqu’on s’est concentré sur des cas singuliers. Cela résulte de l’incompatibilité des structures causales qui sous-tendent la formulation théorique utilisée et l’étude de cas. Pour mettre en évidence cette situation, je considère la dimension méthodologique présente dans l’émergence du concept de présidentialisme de coalition. Le débat actuel porte encore une conception épistémologique imprécise quant à l’usage théorique qui prédisait l’impasse institutionnelle provoquée par la Constitution de 1988. Cette analyse s’avère pertinente à la fois parce que ce constat est absent d’une partie des recherches actuelles, mais aussi pour mettre en évidence l’affinité entre production méthodologique et formulation théorique en Science Politique, mais aussi pour ses effets sur la conception des recherches. dimportants d importants épistémologiques consolidées lévaluation l évaluation limpact impact lorsquon lorsqu on sest s singuliers lincompatibilité incompatibilité soustendent sous tendent létude étude situation lémergence émergence coalition lusage usage limpasse impasse 1988 savère avère dune actuelles laffinité affinité Politique 198 19 1

Resumo O progresso metodológico da Ciência Política nas últimas três décadas gerou importantes alterações epistemológicas, cujos efeitos afetam o alcance de teorias consolidadas. Dentre estas mudanças, argumento que a avaliação causal do impacto de instituições sobre o comportamento político enfrenta desafios que têm sido desconsiderados quando se voltam a casos singulares. Isto decorre da incompatibilidade das estruturas causais subjacentes à formulação teórica utilizada e ao estudo de caso. Para evidenciar esta situação, considero a dimensão metodológica presente no surgimento do conceito de presidencialismo de coalizão. À luz dos avanços metodológicos contemporâneos, a discussão ainda carrega uma concepção epistemológica imprecisa, notada no uso teórico que previa o impasse institucional originado pela Constituição de 1988. Esta análise mostra-se relevante tanto porque esta constatação se ausenta em parte das pesquisas atuais, quanto por ressaltar a afinidade entre a produção metodológica e a formulação teórica na Ciência Política, como também por seus efeitos sobre desenhos de pesquisa. epistemológicas consolidadas mudanças singulares caso situação coalizão contemporâneos imprecisa 1988 mostrase mostra atuais pesquisa 198 19 1

Resumen El avance metodológico de la Ciencia Política en las últimas tres décadas ha generado importantes cambios epistemológicos, cuyos efectos afectan el alcance de las teorías consolidadas. Entre estos cambios, sostengo que la evaluación causal del impacto de las instituciones en el comportamiento político enfrenta desafíos que han sido ignorados al centrarse en casos singulares. Esto surge de la incompatibilidad de las estructuras causales que subyacen a la formulación teórica utilizada y el estudio de caso. Para resaltar esta situación, considero la dimensión metodológica presente en el surgimiento del concepto de presidencialismo de coalición. El debate actual aún conlleva una concepción epistemológica imprecisa sobre el uso teórico que predijo el impasse institucional provocado por la Constitución de 1988. Este análisis resulta relevante tanto porque este hallazgo está ausente en parte de las investigaciones actuales, como por resaltar la afinidad entre producción metodológica y formulación teórica en la Ciencia Política, y también por sus efectos en el diseño de la investigación. epistemológicos consolidadas singulares caso situación coalición 1988 actuales investigación 198 19 1

Abstract The methodological progress of Political Science in the last three decades has generated important epistemological changes, the effects of which affect the scope of consolidated theories. Among these changes, I argue that the causal assessment of the impact of institutions on political behavior faces challenges that have been disregarded when focusing on singular cases. This arises from the incompatibility of the causal structures underlying the theoretical formulation used and the case study. To highlight this situation, I consider the methodological dimension present in the emergence of the concept of coalition presidentialism. The present debate still carries an imprecise epistemological conception concerning the theoretical use that predicted the institutional impasse caused by the 1988 Constitution. This analysis proves to be relevant both because this finding is absent in part of current research, as well as for highlighting the affinity between methodological production and theoretical formulation in Political Science, and also for its effects on research designs. changes theories cases study situation presidentialism 198 Constitution designs 19 1

Resumen Marco contextual: Se ha reportado la participación de distracciones en errores clínicos y fallos de procedimiento. Objetivo: Analizar las distracciones del personal de enfermería durante la preparación y administración de fármacos de alto riesgo. Metodología: Estudio transversal desarrollado en una unidad de cuidados intensivos y una unidad de hospitalización. Se observaron distracciones del personal de enfermería durante el proceso de medicación a través de dos listas de control. La muestra fue seleccionada por conveniencia (abril-mayo 2019). Los datos cuantitativos se analizaron mediante estadística descriptiva (IBM SPSS Statistics, versión 24.0). Los datos cualitativos se analizaron mediante análisis de contenido. Resultados: Hubo 137 distracciones en 193 procesos de medicación. La mayoría de las distracciones fueron iniciadas por otros miembros del equipo sanitario a través de conversaciones. La mayoría se produjeron en la fase de preparación y fueron negativas y se gestionaron mediante la estrategia multitarea. Conclusión: Las distracciones durante el proceso de medicación se referían principalmente a las comunicaciones profesionales y sociales. La importancia de esas distracciones variaba en función de la fase del proceso.

Resumo Enquadramento: Estudos indicam que as interrupções contribuem para erros clínicos e falhas em procedimentos. Objetivo: Analisar as interrupções vivenciadas pelos enfermeiros durante a preparação e administração de medicamentos de alto risco. Metodologia: Foi realizado um estudo transversal numa unidade de cuidados intensivos e numa unidade de internamento. As interrupções vivenciadas pelos enfermeiros durante o processo de medicação foram observadas com a ajuda de duas checklists. A amostra foi selecionada por conveniência em abril e maio de 2019. Os dados quantitativos foram analisados através de estatística descritiva no programa IBM SPSS Statistics, versão 24.0, enquanto os dados qualitativos foram tratados por meio da análise de conteúdo. Resultados: Observaram-se 137 interrupções em 193 processos de medicação. A maioria das interrupções foi iniciada por outros membros da equipa de cuidados de saúde por meio de conversas. Estas interrupções foram maioritariamente prejudiciais e ocorreram durante a fase de preparação. A estratégia multitarefa foi utilizada para as gerir. Conclusão: As interrupções ocorridas durante o processo de medicação eram maioritariamente associadas com comunicações profissionais e sociais. A sua relevância diferiu consoante a fase do processo.

Abstract Background: Interruptions have been reported to contribute to clinical errors and procedural failures. Objective: To analyze the interruptions experienced by nurses during the preparation and administration of high-risk medications. Methodology: A cross-sectional study was conducted in an intensive care and inpatient unit. The interruptions experienced by nurses during the medication process were observed through two checklists. The sample was selected by convenience in April-May 2019. Descriptive statistics was used to analyze quantitative data in IBM SPSS Statistics software, version 24.0, while content analysis was used to analyze qualitative data. Results: In 193 medication processes, there were 137 interruptions. Other members of the healthcare team initiated most interruptions through conversations. These interruptions were mostly negative and occurred during the preparation phase. The multitasking strategy was used to manage them. Conclusion: Interruptions during the medication process were primarily associated with professional and social communications. The impact of these interruptions varied depending on the phase of the process.

Abstract As is well known, Divina Commedia is presented as a work capable of embracing a wide range of “disciplinary meanings”: in its literary form, it embraces in its development, the crossing - through the play of the allegories - of historical questions, cartographic descriptions and philosophical perspectives. For this reason, beyond mere philological criticism, different philosophers have also directed their investigative gaze towards the Dantesque text. The objective of this essay is, therefore, to try to show how some of the many philosophical readings of the work are combined, especially considering the idea of the figure of homo viator, adopted as a fundamental interpretative key by Romano Guardini, in his interpretation of the possible philosophy of the Divina Commedia.

Resumen Como se sabe, la Divina Commedia se presenta como una obra capaz de abrazar un amplio abanico de “sentidos disciplinares”: en su forma de obra literaria, abraza en su desarrollo, el cruzarse -mediante el juego de las alegorías- de cuestiones históricas, descripciones cartográficas y perspectivas filosóficas. Por esta razón, más allá de la mera crítica filológica, también diferentes filósofos han dirigido su mirada investigadora hacia el texto dantesco. El objetivo de este ensayo es, por lo tanto, tratar de mostrar en qué forma se conjugan unas de las tantas lecturas filosóficas de la obra, sobre todo a la luz de la idea de la figura del homo viator, adoptada como clave interpretativa fundamental por Romano Guardini, en su interpretación de la posible filosofía de la Divina Commedia.

Abstract Jouni-Matti Kuukkanen has theorized that narrative does not involve rational content. Rather, he suggested, narrative is only a descriptive practice consisting of singular statements. Kuukkanen thus divorced the rational and narrative frameworks, arguing that historiography belongs to the former and not the latter. This article establishes a new conceptual framework that provides a revised understanding of narrative as a rational practice. I argue that the principles of organization brought to light by the Gestalt school of experimental psychology illuminate the underlying organizational logic that historians engage with when constructing narratives. To illustrate how these principles operate in historical narratives and how they are rational, I examine classic historical works such as Karl Marx’s introduction of the concept of surplus value; Giambattista Vico’s Autobiography and Jacob Burckhardt’s The Civilization of the Renaissance; Reinhart Koselleck’s Futures Past; and E. P. Thompson’s The Making of the English Working Class and Johan Huizinga’s Waning of the Middle Ages. My analysis shows that narrative entails its own kind of explanatory structure. It is a way of thinking that provides meaning and structure to that which is otherwise unstructured and undetermined. Finally, my new framework offers a foundation for the rational evaluation of narratives by showing how the context of discovery and the context of justification cannot be separated in the case of narrative histories.

Resumen Jouni-Matti Kuukkanen ha teorizado que las narrativas no involucran un tipo de actividad racional, en cambio, parecieran ser sólo una práctica descriptiva que consiste en afirmaciones singulares. Es así que Kuukkanen separa el marco racional del narrativo, argumentando que la historiografía pertenece al primero y no al segundo. Este artículo establece un nuevo marco conceptual que proporciona una comprensión revisada de la narrativa como práctica racional. Sostengo que los principios de organización sacados a la luz por la escuela de psicología experimental de la Gestalt iluminan la lógica organizacional subyacente con la que se involucran los historiadores cuando construyen narrativas. Para ilustrar cómo operan estos principios en las narrativas históricas y cómo son racionales, examino obras históricas clásicas como la introducción del concepto de plusvalía de Karl Marx; la Autobiografía de Giambattista Vico y La civilización del Renacimiento en Italia de Jacob Burckhardt; Futuro Pasado de Reinhart Koselleck; y La formación de la clase obrera en Inglaterra de E.P Thompson y El Otoño de la Edad Media de Johan Huizinga. Mi análisis muestra que la narrativa implica su propio tipo de estructura explicativa ya que es una forma de pensar que proporciona significado y estructura a lo que de otro modo está desestructurado y es indeterminado. Finalmente, mi nuevo marco ofrece una base para la evaluación racional de las narrativas al mostrar cómo el contexto de descubrimiento y el contexto de justificación no pueden separarse en el caso de las historias narrativas.

Resumo A expansão desordenada das cidades é um desafio global que afeta o desenvolvimento urbano. Neste estudo, é analisado o crescimento urbano em uma cidade média durante cinco décadas, com enfoque na forma urbana e aplicação de mais de 20 métricas espaciais associadas à mensuração da geometria da expansão físico-territorial no ambiente construído. Os padrões de crescimento são analisados à luz do fenômeno espraiamento urbano e sob a perspectiva da teoria de Difusão-Coalescência. São discutidas as limitações inerentes às métricas existentes, assim como elencadas alternativas que as superam por mensuração das propriedades de Compacidade, Fragmentação, Complexidade e Dispersão concomitantemente. Os resultados demonstraram a ocorrência de fases distintas no crescimento urbano ao longo das décadas: Difusão de uma forma inicialmente compacta em partes menores nas periferias; e Transição para crescimento com agrupamento dessas partes, elevando a compacidade. Essa oscilação sugere aderência à teoria da Difusão-Coalescência, com ocorrência de espraiamento urbano (entre 1966 e 1976) seguida de aumento da compacidade nas décadas subsequentes (1976-2006). Após 2006 os resultados são ambíguos, possivelmente associados a fatores intervenientes de planejamento. A discussão dos resultados destaca a relevância da quantificação do crescimento urbano por meio de métricas, e traz conceitos importantes atualmente limitados à literatura internacional. estudo 2 físicoterritorial físico territorial construído DifusãoCoalescência. DifusãoCoalescência Coalescência. Coalescência Difusão-Coalescência existentes Compacidade Fragmentação concomitantemente periferias DifusãoCoalescência, Coalescência, entre 196 1976 19762006. 19762006 . (1976-2006) 200 ambíguos planejamento internacional 19 197 1976200 (1976-2006 1 197620 (1976-200 19762 (1976-20 (1976-2 (1976- (1976 (197 (19 (1 (

Abstract The disorderly expansion of cities is a global challenge that impacts urban development. In this paper, we analyse the urban growth in a medium-sized city over five decades, focusing on urban form and employing more than 20 spatial metrics associated with the geometry of physical-territorial expansion in the built environment. We examine the growth patterns in the context of the urban sprawl phenomenon and the Diffusion-Coalescence theory perspective. We discuss the inherent limitations of existing metrics and raise alternatives that simultaneously address the properties of Compactness, Fragmentation, Complexity, and Dispersion. The results reveal distinct phases in urban growth over the decades, from diffusion of an initially compact form into smaller parts on the periphery; to a transition towards more compact growth. This oscillation suggests adherence to the Diffusion-Coalescence theory, with urban sprawl occurring between 1966 and 1976, followed by increased compactness in subsequent decades (1976-2006). After 2006, the results became ambiguous, possibly due to intervening planning factors. The discussion of the findings underscores the importance of quantifying urban growth using metrics and introduces concepts that have been hitherto limited to international literature. development paper mediumsized medium sized 2 physicalterritorial physical territorial environment DiffusionCoalescence Diffusion Coalescence perspective Compactness Fragmentation Complexity Dispersion periphery 196 1976 19762006. 19762006 2006 . (1976-2006) ambiguous factors literature 19 197 1976200 200 (1976-2006 1 197620 (1976-200 19762 (1976-20 (1976-2 (1976- (1976 (197 (19 (1 (

Abstract This article aims to examine the evolution of China’s foreign policy from the adoption of the “peaceful rise” policy to the present one which stems from the concept of the “Chinese dream” presented by Xi Jinping. The analysis is carried out in the light of major traditional international relations theories and introduces the doctrine underpinning the “Chinese dream” known as Tianxia. It finds that western traditional doctrine lacks rigorous consideration of Asian historical and cultural singularities that prevent them from fully explaining the international actions of the People’s Republic of China. In particular, China’s increasing assertiveness in its international relations along with its economic, military and technological advances, as well as the military conflicts in Ukraine and Israel, have exacerbated differences with the West. It is imperative to provide diplomacy with tools to assess the international context and the opposing positions of the West and the PRC that considers a theoretical framework that incorporates elements such as Tianxia, not as a substitute for Western tradition frameworks of analysis, but to enrich them. This is particularly true for the defense and projection of the interests of developing countries, which will require extensive diplomatic skills to navigate this complex context effectively as proactive players rather than bystanders in the international arena.

Resumen Este artículo tiene como objetivo examinar la evolución de la política exterior china desde la adopción de la política del “ascenso pacífico” hasta la actual, basada en el concepto del “sueño chino” expuesto por Xi Jinping. El análisis se lleva a cabo a la luz de las principales teorías de relaciones internacionales tradicionales e introduce la doctrina que sustenta al “sueño chino” conocida como Tianxia. Se encuentra que la doctrina occidental tradicional carece de una consideración rigurosa de las aristas históricas y culturales asiáticas y esto le impide explicar plenamente el comportamiento internacional de la República Popular China (RPC). En particular, la creciente asertividad de China en sus relaciones internacionales junto a sus avances económicos, militares y tecnológicos, así como los conflictos militares en Ucrania e Israel, han exacerbado las diferencias con Occidente. Es imperativo dotar a la diplomacia de herramientas que permitan valorar el contexto internacional y las posiciones contrapuestas entre Occidente y la RPC a partir de un marco teórico que incorpore elementos como el Tianxia, no en sustitución de los esquemas de análisis de tradición occidental, sino en adhesión, para enriquecerlos. Esto es particularmente cierto, para la defensa y proyección de los intereses de los países en desarrollo, los cuales requerirán de amplias destrezas diplomáticas para navegar este complejo contexto de manera efectiva, como actores proactivos y no espectadores en la arena internacional.

Resumen La investigación tuvo como objetivo comprender las experiencias alrededor de la sexualidad desde la teoría de los holones en un grupo de mujeres diagnosticadas con cáncer ginecológico en la ciudad de Pereira, Colombia. Se implementó un diseño cualitativo y fenomenológico, con la participación de seis mujeres entre 30 y 60 años, a quienes se aplicaron entrevistas semiestructuradas explorando los holones de reproductividad, género, erotismo y vinculación afectiva interpersonal. Las entrevistas fueron transcritas y analizadas de forma manual, mediante codificación abierta y axial para identificar categorías emergentes. En los discursos de las mujeres se evidenciaron elementos relacionados a los holones de la sexualidad. En el holón de reproductividad, se encontró una resignificación del rol reproductivo como madres; en el holón de género, se presentaron actitudes positivas hacia el cuerpo y amenazas a la identidad de género por causa de los cambios provocados por la enfermedad; en el holón de erotismo, las mujeres relataron experiencias sexuales marcadas por el dolor y el apoyo erótico de la pareja; y en el holón de vinculación afectiva interpersonal, se evidenciaron situaciones de estabilidad conyugal, separación temporal con la pareja y sostenimiento de vínculos abusivos durante el proceso de tratamiento oncológico. Estos hallazgos muestran una amplia reconfiguración integral de la sexualidad femenina en cada uno de los holones y realizan un aporte significativo a la comprensión de las subjetividades de las mujeres en el proceso de afrontar el cáncer ginecológico. Se recomienda realizar nuevas investigaciones con mayor cantidad de participantes y en otras regiones de Colombia.

Abstract The research aimed to understand the experiences around sexuality, from the holon theory, in a group of women diagnosed with gynecological cancer from Pereira, Colombia. A qualitative and phenomenological design was carried out, with the participation of six women between 30 and 60 years of age, to whom semi-structured interviews were applied, exploring the holons of reproductivity, gender, eroticism and interpersonal affective bonding. The interviews were transcribed and analyzed manually, using open and axial coding to identify emerging categories. In the women's discourses, elements related to the holons of sexuality were evident. In the holon of reproductivity, a resignification of the reproductive role as mothers was found; in the holon of gender, positive attitudes towards their bodies and threats to gender identity due to the changes caused by the disease were presented; in the holon of eroticism, women reported sexual experiences characterized by pain and erotic support from their partners; and in the holon of affective interpersonal bonding, they reported situations of marital stability, temporary separation from their partners and abusive ties during the process of cancer treatment. These findings show a comprehensive reconfiguration of female sexuality in each of the holons and make a significant contribution to the understanding of women's subjectivities in the process of coping with gynecological cancer. Further research with a larger number of participants and in other regions of Colombia is recommended.

Abstract The objective of this research is to identify and describe the main domains and subdomains of the entrepreneurial ecosystem that drive entrepreneurship in Mexico and establish their relationship with the entrepreneurial intention. For this purpose, a structured direct questionnaire was developed which was applied to 1,141 students of accounting, administration, and computer science majors, from the Faculty of Accounting and Administration of the National Autonomous University of Mexico. A descriptive, correlational, and multivariate analysis was carried out. The results allow to know that the training of an entrepreneur integrates social, cultural and economic knowledge, which increases the probability of creating successful entrepreneurship; however, knowledge of the business environment does not represent a strength for students, specifically they lack knowledge about the financing sources. Regarding the students' perception about the market and human capital, it was found that they have a notion of the elements that allow increasing sales in an organization and know how to recognize the importance of human capital. On the other hand, students express concern about procedures and corruption, which are barriers that usually prevent entrepreneurship in Mexico; likewise, they require more information about entrepreneurship support services.

Resumen El objetivo de esta investigación es identificar y describir los principales dominios y subdominios del ecosistema emprendedor que favorecen el emprendimiento en México, y establecer su relación con la intención de emprendimiento, para ello se elaboró un cuestionario directo estructurado el cual fue aplicado a 1,141 estudiantes de las carreras de contaduría, administración e informática, de la Facultad de Contaduría y Administración de la Universidad Nacional Autónoma de México, se realizó un análisis descriptivo, correlacional y multivariado. Los resultados permiten saber que la formación de un emprendedor integra conocimientos sociales, culturales y económicos, lo cual incrementa las probabilidades de crear emprendimientos exitosos, sin embargo, el conocimiento del ambiente empresarial no representa una fortaleza para los estudiantes, específicamente carecen de conocimientos sobre las fuentes de financiamiento. Respecto a la percepción de los estudiantes acerca del mercado y del capital humano, se encontró que estos tienen noción de los elementos que permiten incrementar las ventas en una organización y saben reconocer la importancia del capital humano. Por otra parte, los estudiantes manifiestan preocupación por los trámites y la corrupción que son barreras que suelen impedir el emprendimiento en México; asimismo, requieren de más información sobre de los servicios de apoyo al emprendimiento.

RESUMEN En este artículo se buscará desarrollar un análisis de la teoría aristotélica de la sustancia, específicamente de la discusión en torno a su particularidad o universalidad. Primero revisaremos el planteamiento del problema tal como aparece en Categorías. Posteriormente, llevaremos la discusión a Metafísica, específicamente el libro Z, donde se puede encontrar una visión más desarrollada y elaborada de las ideas expuestas por el filósofo que en el Organon. A partir de allí revisaremos la visión universalista y particularista para evaluarlas en su mérito e intentar determinar cuál de las dos resulta ser más adecuada para la ontología aristotélica. Finalmente, se revisarán algunas posibles soluciones al problema de cognoscibilidad que presenta la visión particularista y se intentará dilucidar esos problemas a la luz de la aplicación que tiene cuando se transporta el conflicto al problema del alma en De Anima.

ABSTRACT In this paper, we seek to develop an analysis of the Aristotelian theory of substance, specifically of the discussion about its particularity or universality. We will first review the statement of the problem as it appears in Categories. We will then take the discussion to Metaphysics, specifically book Z, where a further developed and elaborated view of the ideas presented by the philosopher can be found compared to the Organon. From there we will review the universalist and particularist views to evaluate them on their merit and try to determine which of the two turns out to be more adequate for Aristotelian ontology. Finally, we will review some possible solutions to the problem of cognizability presented by the particularist view and attempt to clarify these problems in light of the application it has when the conflict is transposed to the problem of the soul in De Anima.

Abstract Light wells in residential buildings represent a context that has received relatively little attention in daylighting analyses. This study aims to analyze the daylighting performance of a residential space with a window facing a light well, in order to contribute to the revision of NBR 15575:2013. The study conducted 1,152 daylighting analyses considering windows facing a light well, located on the first and fourth floors of a 4-story building. Clear and intermediate skies were considered in four Brazilian cities with different latitudes. Both the prescriptive method and point-in-time simulations were applied. The effectiveness of achieving daylit interior spaces through light wells strongly depends on the geometry of the light well and the external illuminance conditions of the city. Narrow light wells were found to be unsuitable for adequately daylighting the lower floor spaces. Furthermore, the prescriptive method was insufficient in representing daylighting originating solely from external wall interreflections. The study found that intermediate and superior performance levels, when achieved through point-in-time or spatial daylighting availability simulations, were never attained for the first-floor space. Therefore, the authors recommend that dense urban canyon situations and light wells be carefully considered in the revision of the standard. 155752013. 155752013 15575 2013. 2013 15575:2013 1152 1 152 1,15 4story story 4 building latitudes pointintime point time applied city Furthermore interreflections levels firstfloor Therefore standard 15575201 1557 201 15575:201 115 15 1,1 1557520 155 20 15575:20 11 1, 155752 2 15575:2 15575:

Resumo Poços de luz em edifícios residenciais representam um contexto com pouca atenção nas análises de iluminação natural. Esse estudo propõe analisar o desempenho de iluminação natural de um espaço residencial com janela voltada para poço de luz visando objetivo de contribuir com a revisão da NBR 15575:2013. O estudo realizou 1.152 análises de desempenho considerando a janela voltada para o poço de luz localizada no 1º e 4º pavimentos de uma edificação de quatro pavimentos. Foram considerados céu claros e intermediários em quatro cidades brasileiras com diferentes latitudes. O método prescritivo e simulação ponto-no-tempo foram aplicados. A solução de iluminação de espaços internos por meio de poços de luz depende fortemente de sua geometria e das condições de iluminância externa da cidade. Poços estreitos mostraram-se inaptos para levar luz suficiente para os ambientes inferiores. O método prescritivo não é capaz de representar adequadamente situações de iluminação natural oriunda exclusivamente de interreflexões de paredes externas. Os níveis intermediários e superiores de desempenho por simulação ponto-no-tempo ou por análises baseadas no clima não foram atendidos no 1º pavimento. Os autores recomendam que situações de cânions urbanos densos e poços de luz sejam cuidadosamente consideradas na análise da revisão da norma. 155752013. 155752013 15575 2013. 2013 15575:2013 1152 1 152 1.15 º latitudes pontonotempo ponto tempo aplicados cidade mostraramse mostraram se inferiores externas pavimento norma 15575201 1557 201 15575:201 115 15 1.1 1557520 155 20 15575:20 11 1. 155752 2 15575:2 15575:

Abstract Introduction. Sustainable practices are important tools for mitigating and adapting to climate change, making it essential to understand the factors influencing rice producers’ decisions to adopt conservation practices in their production system. Objective. To determine the causal relationships between variables that explain the adoption of conservation practices by rice producers. Materials and methods. A study was conducted between July and September 2021 in rice production systems in Costa Rica, involving producers from the Brunca, Chorotega, Huetar, and Central Pacific regions through quota sampling. A survey was administered to a total of 67 rice producers. The research was quantitative, identifying degrees of adoption of conservation practices, performing cluster groupings, and using an ordered probit model was to analyze the factors influencing the intensity of adoption of conservation technologies or practices in these production systems. Results. Greater adoption of conservation practices in rice production systems was influenced by the producer’s level of education, membership or affiliation with organizations in rice sector, and land ownership. Conclusions. The design of strategies for conservation practice in rice cultivation benefits from a better understanding of the relationships between socioeconomic, productive, and environmental variables, which can increase the likelihood that a producer will implement and maintain these conservation practices over time.

Resumen Introducción. Las prácticas sostenibles son importantes como herramientas de mitigación y adaptación al cambio climático, por lo que es oportuno comprender qué factores influencian las decisiones de las personas productoras del cultivo de arroz en adoptar una práctica de conservación en su sistema de producción. Objetivo. Determinar las relaciones causales entre las variables que permiten entender la adopción de prácticas de conservación en el cultivo del arroz por parte de las personas productoras. Materiales y métodos. Se realizó un estudio entre julio y septiembre del 2021 en los sistemas productivos de arroz en Costa Rica, con personas productoras de las regiones Brunca, Chorotega, Huetar y Pacífico Central, a través de un muestreo por cuotas. Se aplicó una encuesta a un total de 67 personas productoras de arroz. La investigación realizada fue cuantitativa y se identificaron grados de adopción de prácticas de conservación, se realizaron agrupaciones mediante clústeres y se utilizó un modelo probit ordenado para analizar los factores que influyen en la intensidad de adopción de tecnologías o prácticas de conservación en estos sistemas productivos. Resultados. Una mayor adopción de prácticas de conservación en los sistemas productivos del cultivo de arroz estuvo influenciada por el nivel de escolaridad de la persona productora, la pertenencia o afiliación a organizaciones del sector arrocero y la tenencia de la tierra. Conclusiones. El diseño de estrategias de prácticas de conservación en el cultivo del arroz se beneficia de una mejor comprensión de las relaciones entre las variables socioeconómicas, productivas y del entorno, que permitan aumentar la probabilidad de que una persona productora implemente y mantenga en el tiempo el uso de estas prácticas de conservación.

Abstract Introduction. Seedlings formation under controlled conditions is crucial for cultivating species like strawberry. With LED artificial lighting technology allowing greater control over light, variations in components such as wavelength and intensity can be manipulated to generate seedlings with different characteristics. However, there is a need to generate information for the development of precise and efficient light control practices. Objective. The evaluate strawberry seedling formation under different intensities of violet, blue, and red LED light. Material and methods. The study was conducted in 2020 at the Plant Genetics Laboratory of the Department of Agronomy at the Universidad de Guanajuato, Guanajuato, Mexico. Seeds from San Andreas variety fruits were collected, and seedlings were grown under violet, blue, and red LED light at high, medium, and low intensities. Color determinations of cotyledon area, Chroma saturation index, and Hue angle were performed. Additionally, physio-technical, chemical, and antioxidant activity variables were measured. Results. The most suitable treatments were high and medium intensity violet light, as well as high intensity blue light, with germination range exceeding 60 %. Seedlings did not elongate or thin out and exhibited the largest cotyledons areas and chlorophyll concentrations. Furthermore, these light treatments consumed, on average, 31.2 % less electrical energy. Conclusions. In addition to white light, the most suitable treatments for strawberry seedlings formation were high and medium intensity violet light, as well as high intensity blue light. It is suggested to evaluate violet and blue light treatments in other cultivars to confirm their positive effect on strawberry seedlings. Red light limited germination and showing higher antioxidant activity.

Resumen Introducción. La formación de plántulas en condiciones controladas es fundamental para cultivar especies como la fresa. Dado que la tecnología de iluminación artificial LED ha permitido un mayor control de la luz, la variación de componentes como la longitud de onda y la intensidad pueden ser manipulados para generar plántulas con diferentes características. Sin embargo, es necesario generar información para el desarrollo de prácticas precisas y eficientes en el control de la luz. Objetivo. Evaluar la formación de plántulas de fresa en diferentes intensidades de luz LED violeta, azul y roja. Materiales y métodos. El estudio se realizó durante 2020 en el Laboratorio de Genética Vegetal del Departamento de Agronomía de la Universidad de Guanajuato, Guanajuato, México. Se recuperaron semillas de frutos de la variedad San Andreas y se sembraron plántulas en luz LED violeta, azul y roja a intensidades alta, media y baja. Se realizaron determinaciones de color del área del cotiledón, índice de saturación de color y ángulo Hue. Además, se midieron variables fisiotécnicas, químicas y actividad antioxidante. Resultados. Los tratamientos más adecuados fueron luz violeta de intensidades altas y medias; así como luz azul de alta intensidad, debido a que el porcentaje de germinación superó el 60 %. Las plántulas no se alargaron ni adelgazaron, presentaron las mayores áreas de cotiledones y concentraciones de clorofila. Además, estos tratamientos de luz consumieron en promedio 31,2 % menos energía eléctrica. Conclusiones. Además de la luz blanca, los tratamientos más adecuados para la formación de plántulas de fresa fueron la luz violeta a alta y media intensidad, así como la luz azul a alta intensidad. Se sugiere evaluar los tratamientos de luz violeta y azul en otros cultivares para confirmar el efecto positivo en las plántulas de fresa. La luz roja limitó la germinación y mostró mayor actividad antioxidante.