RESUMO Objetivo: Descrever as características epidemiológicas de pacientes pediátricos com doença falciforme (DF) e avaliar o uso de plantas medicinais concomitantemente ao tratamento medicamentoso. Métodos: Realizou-se revisão de prontuários de pacientes pediátricos de uma instituição pública com nível de atendimento terciário; o critério de seleção foi ser criança ou adolescente com DF em acompanhamento pediátrico neste ambulatório. Nos prontuários dos pacientes selecionados foi procurado o registro do uso de plantas com finalidades medicinais. Resultados: Foram revisados 154 prontuários (100% dos pacientes ativos desse ambulatório): 99 crianças e 55 adolescentes. O genótipo predominante foi SS (58,4%), seguido do SC (29,2%). O uso de ao menos uma medicação para a DF foi relatada em 95,5% dos prontuários. Em 70,1% dos prontuários havia o relato do uso de plantas medicinais, em 276 citações, sendo 64 plantas citadas ao todo; destas, seis espécies foram citadas para o tratamento da doença de base (DF), sendo “ora-pro-nobis” (Pereskia aculeata) a principal. Das 276 citações de plantas medicinais nos prontuários, 60,5% incluíram o uso de plantas medicinais em sintomas gripais e/ou COVID-19 (tanto prevenção quanto tratamento), sendo relatadas 35 para este uso, exclusivamente ou não. Essa foi a principal finalidade de uso encontrada nos prontuários dos pacientes, seguida do uso para sintomas de dor (14,2% das citações). Conclusões: Notou-se que a maioria dos pacientes avaliados faz uso da medicina convencional, aliada à tradicional/ complementar/ alternativa, o que leva à necessidade de mais estudos nessas áreas, especialmente na pediatria, visando principalmente à segurança do paciente. Objetivo (DF medicamentoso Métodos Realizouse Realizou se terciário ambulatório Resultados 15 100% 100 (100 ambulatório) 9 5 adolescentes 58,4%, 584 58,4% , 58 4 (58,4%) 29,2%. 292 29,2% . 29 2 (29,2%) 955 95 95,5 701 70 1 70,1 27 6 todo destas DF, orapronobis ora pro nobis “ora-pro-nobis Pereskia aculeata 605 60 60,5 eou COVID19 COVID 19 COVID-1 tanto tratamento, tratamento) 3 não 14,2% 142 14 (14,2 citações. citações) Conclusões Notouse Notou convencional tradicional complementar alternativa áreas pediatria paciente 10 (10 58,4 (58,4% 29,2 (29,2% 95, 7 70, 60, COVID1 COVID- 14,2 (14, (1 58, (58,4 29, (29,2 14, (14 ( (58, (29, (58 (29 (5 (2

ABSTRACT Objective: The aim of this study was to describe the epidemiological characteristics of pediatric patients with sickle cell disease (SCD) and evaluate the use of medicinal plants in these patients concomitantly with their drug treatment. Methods: This is a review of the medical records of pediatric patients at a public institution with tertiary care. The selection criterion was to be a child or adolescent with SCD undergoing pediatric follow-up at this outpatient clinic. In the medical records of the patients selected, records of the use of plants for medicinal purposes were sought. Results: In total, 154 records (100% of total active patients followed in this clinic) were reviewed: 99 children and 55 adolescents. The predominant genotype was SS (58.4%), followed by SC (29.2%). The use of at least one medication for SCD was reported in 95.5% of the medical records. The use of medicinal plants was reported by 70.1% of patients, with 276 citations in the medical records referring to 64 different types of plants. Six plants were used for the treatment of SCD, the main one being Lemonvine/Ora-pro-nóbis (Pereskia aculeata). The use of medicinal plants was reported for flu-like symptoms and/or COVID-19 (both for prevention and treatment) by 60.5% of the citations, with 35 different plants reported for this use, exclusively or not. This use was followed by pain symptoms (14.2% of citations). Conclusions: The majority of patients in this study use both conventional and traditional/complementary/alternative medicine, highlighting the need for more studies in the area, with a special focus on patient safety. Objective (SCD Methods care followup follow up clinic selected sought Results 15 100% 100 (100 reviewed 9 5 adolescents 58.4%, 584 58.4% , 58 4 (58.4%) 29.2%. 292 29.2% . 29 2 (29.2%) 955 95 95.5 701 70 1 70.1 27 6 Lemonvine/Orapronóbis LemonvineOrapronóbis Lemonvine/Ora pro nóbis Lemonvine Ora Pereskia aculeata. aculeata aculeata) flulike flu like andor COVID19 COVID 19 COVID-1 605 60 60.5 3 not 14.2% 142 14 (14.2 citations. citations) Conclusions traditionalcomplementaryalternative traditional complementary alternative medicine area safety 10 (10 58.4 (58.4% 29.2 (29.2% 95. 7 70. Orapronóbis LemonvineOra COVID1 COVID- 60. 14.2 (14. (1 58. (58.4 29. (29.2 14. (14 ( (58. (29. (58 (29 (5 (2

This paper presents the stages of an acceleration program focused on chemical technologies. We demonstrate how this initiative contributes to the creation of new businesses, startups, and technology licensing from research developed at Brazilian universities. The case of the program Escale-se is discussed. There were 66 technologies submitted, and 14 were selected for the pre-acceleration phase. In this phase, various contents were worked on, such as creating a business model and aspects of scaling hard-science technologies. Teams were evaluated by panels with market specialists, and 6 were selected for the second phase: pre-scaling/proof of concept. Here, proponents were encouraged to validate the business model by connecting with potential clients and partners, as well as planning the development and testing of the product in a relevant environment. Finally, one team was classified for the last stage: scaling/go-to-market - where they received R$ 100,000.00 to scale up their technology and create strategies for raising investments. Four of the fourteen technologies selected for the program opened National Register of Legal Entities (CNPJ) and raised approximately R$ 4.5 M in investments from different sources. These results demonstrate that the methodology contributed to the entrepreneurial development of participating researchers and the raising of funds for the businesses created. startups universities Escalese Escale se discussed submitted 1 preacceleration pre phase hardscience hard science specialists prescaling/proof prescalingproof scaling/proof proof concept Here partners environment Finally stage scaling/gotomarket scalinggotomarket scaling/go go R 10000000 100 000 00 100,000.0 CNPJ (CNPJ 45 4 5 4. sources created prescaling scalingproof gotomarket scalinggo 1000000 10 0 100,000. 100000 100,000 10000 100,00 1000 100,0 100,

In order to extract hesperidin from Citrus aurantium L. through green and efficient ways, a novel method based on deep eutectic solvent (DES) assisted extraction has been developed. Compared to known alkali extraction and acid precipitation or organic solvent (ethanol, methanol) extraction, this new DES system of choline chloride/diethanolamine (DES-14) method exhibited excellent extraction efficiency for hesperidin. Under optimal conditions, the extraction yield of hesperidin reached 6.26 ± 0.05%. Further studies with infrared spectroscopy, 1H nuclear magnetic resonance, and density functional theory showed the DES-14 was formed mainly through the interaction of H-bond and van der Waals forces. In addition, scanning electron microscopy and density functional theory revealed the strong dissolving capacity, and the H-bond formation between DES-14 and hesperidin, as well as van der Waals forces all contributed to efficient extraction of hesperidin. The results provide a new strategy for efficient extraction and utilization of hesperidin in Citrus. L ways (DES developed ethanol, ethanol (ethanol methanol chloridediethanolamine chloride diethanolamine DES14 14 (DES-14 conditions 626 6 26 6.2 005 0 05 0.05% spectroscopy H resonance DES-1 Hbond bond addition capacity DES1 1 (DES-1 62 2 6. 00 0.05 DES- (DES- 0.0 0.

To discover new bisamide compounds with insecticidal and fungicidal activities, 19 novel cyproflanilide derivatives containing 1,2,4-oxadiazole group were designed and synthesized according to the principle of biologically active factor splicing. Preliminary biological assay data indicated that the majority of target compounds demonstrated significant insecticidal activity against Lepidopteran pests. Meanwhile, compounds 5p and 5q showed 97.22 and 100% lethality against Tetranychus cinnabarinus at 400 mg L-1, which were better than cyproflanilide (41.11% at 400 mg L-1). In addition, it is exciting that we have achieved our initial goals as some of the target compounds exhibited both insecticidal and fungicidal activities. For instance, compounds 5b and 5c showed 59.26 and 74.07% fungicidal activities against Cucumber downy mildew at 400 mg L-1, as well as 100% insecticidal activity against Plutella xylostella and armyworm at 100 mg L-1. Compound 5h showed 100% insecticidal activity against armyworm at 10 mg L-1, and also displayed 66.67% fungicidal activity against Cucumber downy mildew at 400 mg L-1. The inhibition rate of compounds 5l and 5s against Cucumber downy mildew reached 88.89 and 96.30% at 400 mg L-1. This work showed the effectively fungicidal application of 1,2,4-oxadiazole group in bisamide compounds and provides insights for optimal structural design. 1 1,2,4oxadiazole 124oxadiazole oxadiazole 1,2,4 2 4 splicing pests Meanwhile p q 9722 97 22 97.2 40 L1, L1 L 1, L-1 41.11% 4111 41 11 (41.11 L1. . L-1) addition instance b c 5926 59 26 59.2 7407 74 07 74.07 1. h 6667 66 67 66.67 l s 8889 88 89 88.8 9630 96 30 96.30 design 4oxadiazole 124 1,2, 972 9 97. L- 41.11 411 (41.1 592 5 59. 740 7 0 74.0 666 6 66.6 888 8 88. 963 3 96.3 12 1,2 41.1 (41. 74. 66. 96. 41. (41 (4 (

RESUMO Este artigo propõe um modelo conceitual para avaliar como a motivação materialista dos consumidores impacta as características sociais (prestígio e conspicuidade) que geram Status para produtos tecnológicos inovadores, que podem levar à intenção de consumo. O estudo utilizou uma abordagem quantitativa para testar um modelo conceitual utilizando a modelagem de equações estruturais com o uso do PLS - SEM. Os resultados indicam que o prestígio do produto e a percepção de conspicuidade do produto medeiam a motivação materialista dos consumidores, o que afeta o status social proporcionado pelo produto ao indivíduo. Da mesma forma, a percepção de inovação e o status do produto medeiam a relação entre conspicuidade e prestígio percebido em relação à intenção de consumo. Esta pesquisa fornece insights importantes sobre as fortes relações entre as características sociais do produto tecnológico que levam em conta os valores dos indivíduos. Como consequência, este estudo contribui diretamente na compreensão de status e valores sociais influenciando a intenção de consumo de produtos tecnológicos, demonstrando o quanto a inovação traz elementos de valoração do indivíduo que a possui. inovadores SEM forma indivíduos consequência possui

ABSTRACT This article proposes a conceptual model to assess how consumers' materialistic motivations impact social characteristics (prestige and conspicuity) that generate status for innovative technological products, which can lead to consumption intention. The study used a quantitative approach to test a conceptual model using structural equation modeling through PLS - SEM. The results indicate that product prestige and perception of product conspicuity mediate consumers’ materialistic motivations, which affects the social status provided to the individual by the product. Likewise, perception of innovation and product status mediate the relationship between conspicuity and perceived prestige in relation to consumption intention. This research yields important insights regarding the strong relations between the social characteristics of technological products that take into account individuals’ values. Consequently, this study enhances understanding of how status and social value influence the intention to consume technological products, demonstrating the extent to which innovation brings elements of value to individuals who own the product in question. consumers SEM Likewise values Consequently question

Resumo A competitividade das empresas do setor de sistemas eletromecânicos de engenharia desempenha um papel fundamental na promoção do crescimento econômico e da inovação. O objetivo deste estudo é desenvolver um índice abrangente para avaliar a competitividade das empresas, com foco na eficiência operacional, posicionamento estratégico e o ambiente internacional. Empregando uma análise fatorial exploratória, os dados foram coletados por meio de um questionário aplicado a 280 empresas em Moscou, Rússia. O índice proposto permite uma avaliação dinâmica da competitividade, permitindo a análise de indicadores-chave ao longo do tempo e prevendo mudanças na competitividade. As conclusões revelam fatores críticos que contribuem para a competitividade no sector, permitindo aos decisores formular estratégias para melhorar a sua posição competitiva. Esta pesquisa fornece informações valiosas para formuladores de políticas, profissionais da indústria e pesquisadores acadêmicos no aumento da competitividade das empresas de sistemas eletromecânicos de engenharia e na promoção do desenvolvimento econômico sustentável. As contribuições do estudo para a literatura e sua relevância prática o tornam um recurso valioso para o público acadêmico e do setor. inovação operacional internacional exploratória 28 Moscou Rússia indicadoreschave indicadores chave sector competitiva políticas sustentável 2

Abstract The competitiveness of enterprises in the electromechanical systems engineering sector plays a crucial role in driving economic growth and innovation. This study aims to design a comprehensive index for evaluating enterprise competitiveness, focusing on operational efficiency, strategic positioning, and the international environment. Employing an exploratory factor analysis, data was collected through a questionnaire administered to 280 enterprises in Moscow, Russia. The proposed index allows for a dynamic assessment of competitiveness, enabling the analysis of key indicators over time and predicting changes in competitiveness. The findings reveal critical factors contributing to competitiveness in the sector, enabling decision-makers to formulate strategies for improving their competitive position. This research provides valuable insights for policymakers, industry practitioners, and academic researchers in enhancing the competitiveness of electromechanical systems engineering enterprises and fostering sustainable economic development. The study's contributions to the literature and its practical relevance make it a valuable resource for academic and industry audiences alike. innovation efficiency positioning environment 28 Moscow Russia decisionmakers decision makers position policymakers practitioners development studys s alike 2

Abstract In this article, the business diagnosis is addressed through a case study focused on Bioeko. The problem context is centered on the need to understand the factors affecting the achievement of an organization's strategic objectives. The aim of the article is to conduct a comprehensive analysis of Bioeko, using an organizational diagnostic tool. The methodology adopted was based on a descriptive and inductive approach backed by a qualitative analysis. An organizational diagnostic tool was developed in Excel that allows the assessment of the organization in five key areas: strategy, finance, marketing, operations, and human resource management. This tool is complemented with specific automatic questionnaires and is based on various dimensions of analysis to evaluate and improve key areas of the company, including the current situation, forecasts, general diagnosis, and results. The study revealed that, despite having strengths in human capital management, Bioeko needs to improve its coordination, marketing, and financial administration to boost its competitiveness. In conclusion, it is argued that the implementation of diagnostic tools will drive continuous improvements in SMEs, promoting innovation and learning through a collaborative working environment. These efforts are fundamental for the growth and sustainable success of small and medium-sized enterprises.

Resumen En este artículo, se aborda el diagnóstico empresarial a través de un estudio de caso centrado en Bioeko. El contexto del problema se centra en la necesidad de comprender los factores que afectan al logro de los objetivos estratégicos de una organización. El objetivo del artículo es realizar un análisis exhaustivo de Bioeko, utilizando una herramienta de diagnóstico organizacional. La metodología adoptada se basó en un enfoque descriptivo e inductivo respaldado por un análisis cualitativo. Se desarrolló una herramienta de diagnóstico organizacional en Excel que permite evaluar la organización en cinco áreas clave: estrategia, finanzas, marketing, operaciones y gestión de recursos humanos. Esta herramienta se complementa con cuestionarios específicos automáticos y se basa en diversas dimensiones de análisis para evaluar y mejorar áreas clave de la empresa, incluyendo la situación actual, previsiones, diagnóstico general y resultados. El estudio reveló que, a pesar de contar con fortalezas en la gestión del capital humano, Bioeko necesita mejorar su coordinación, marketing y administración financiera para impulsar su competitividad. En conclusión, se sostiene que la implementación de herramientas de diagnóstico impulsará mejoras constantes en las Mipymes, fomentando la innovación y el aprendizaje a través de un entorno laboral colaborativo. Estos esfuerzos son fundamentales para el crecimiento y el éxito sostenible de las pequeñas y medianas empresas.

ABSTRACT Purpose: We reported, as a referral center in prostate cancer, our perspectives and experience performing Telesurgery using robotic surgery and 5G network. Material and methods: We described and illustrated the Telesurgery applications and outcomes to treat a patient with prostate cancer located 1300 kilometers away from the surgeon (Beijing-Harbin) in China. We used the Edge Medical Robot (MP1000) in November 2023 in a 71-year-old patient with Gleason 6 (ISUP 1) in 8 cores from 13, PSA of 14 ng/dL, and clinical stage cT2a. MRI described a PIRADS 5 nodule on the left peripheral zone at the base, and 20gr prostate. We described details about the connection between centers, perioperative outcomes, and our perspectives as a referral center in prostate cancer. Results: We had no delays, or problems with network connection between the centers. The procedure was performed in 60 minutes, with no intra- or postoperative complications. Estimated blood loss was 100 mL. The patient was ambulating soon after anesthesia recovery. Final pathology described a Gleason 6 (ISUP 1) involving the left base and left seminal vesicle, negative surgical margins, and no lymph node involvement (pT3bN0). The patient was continent soon after catheter removal (7 days). Conclusion: As technological progress introduced novel robotic platforms and high-speed networks, the concept of Telesurgery became a tangible reality while 5G technology solved latency and transmission concerns. However, with these advancements, ethical considerations and regulatory frameworks should underline the importance of transparency and patient safety with responsible innovation in the field. Purpose reported G methods 130 BeijingHarbin Beijing Harbin (Beijing-Harbin China MP1000 MP (MP1000 202 71yearold yearold 71 year old ISUP 1 13 ngdL ng dL ng/dL cT2a cTa cT gr centers Results delays minutes intra complications 10 mL recovery vesicle margins pT3bN0. pT3bN0 pTbN . pT bN (pT3bN0) 7 ( days. days days) Conclusion highspeed high speed networks concerns However advancements field MP100 (MP100 20 pT3bN (pT3bN0 MP10 (MP10 2 (pT3bN MP1 (MP1 (MP

RESUMEN Las cuatro misiones de la Universidad hacen que esta tenga un papel importante en el desarrollo económico y social a través de la formación del capital humano. Entre las misiones, se encuentran la enseñanza y la investigación. La enseñanza debe llevarse a cabo por medio de la investigación para generar las bases del conocimiento y el desarrollo de este. Además, debe generar el uso del conocimiento, su preservación y difusión mediante la interacción con usuarios. Por eso, se indagó en: 1) la formación de los estudiantes universitarios de Encarnación con relación a la CTI; 2) el índice de universidades de Encarnación que realizan transferencia de conocimiento; 3) la relación entre las MIPYMES y las universidades de Encarnación. Metodológicamente, se trabajó con la metodología cuantitativa-método descriptivo. Se aplicó una encuesta a directivos de 4 universidades privadas de la ciudad. Los resultados dan cuenta de la falta de capital humano calificado en I+D+i dentro de las universidades estudiadas, hecho que dificulta la implementación de las oficinas de transferencia de conocimiento (OTRI) pues la formación relacionada a la investigación e innovación se ven limitadas al no desarrollarse en todos los años de cursada, siendo esto, a nivel de grado y posgrado, además de la escasa actividad de vinculación con el medio. Estos hallazgos resaltan la limitada capacidad para generar nuevos conocimientos contextualizados a la realidad local y a su posterior aplicación eficiente.

ABSTRACT The four missions of the University give it an important role in economic and social development through the formation of human capital. Among the missions are teaching and research. Teaching must be carried out through research to generate the bases of knowledge and its development. It must also generate the use of knowledge, its preservation and dissemination through interaction with users. Therefore, we investigated: 1) the training of university students in Encarnación in relation to STI; 2) the index of universities in Encarnación that carry out knowledge transfer; 3) the relationship between MSMEs and universities in Encarnación. Methodologically, we worked with the quantitative methodology - descriptive method. A sur- vey was applied to managers of 4 private universities in the city. The results show the lack of qualified human capital in R+D+i within the universities studied, a fact that hinders the implementation of knowledge transfer offices (OTRI), since training related to research and innovation is limited because it is not developed in all the years of study, both at the undergraduate and graduate levels, in addition to the limited activity of linking with the environment. These findings highlight the limited capacity to generate new knowledge contextualized to the local reality and its subsequent efficient application.

Abstract: The pandemic period served as a catalyst in the museums' adaptation, leading them to embrace innovation, collaboration, and resilience. As they emerged from the COVID-19 crisis, these institutions found themselves in a unique position to play a vital role in society's rebuilding and in preserving cultural heritage in an ever-changing world. The article aims to explore the main measures adopted, review the scientific literature on the subject, highlight some relevant cases in European, Asian, and American museums, and identify the challenges and dynamics driven in the post-pandemic period. The text stems from a thorough literature review to determine how the museum field should reconfigure its presence, considering three factors: technology, heritage, and audience. A landscape in which the presence of social networks, the rise of online exhibitions, and other digital resources are considered fundamental.

Resumen: El periodo pandémico supuso un catalizador en la adaptación de los museos, llevándolos a abrazar la innovación, la colaboración y la resiliencia. A medida que emergieron de la crisis del covid-19, dichas entidades se encontraron en una posición única para desempeñar un papel vital en la reconstrucción de la sociedad y en la preservación del patrimonio cultural en un mundo en constante cambio. El artículo busca conocer cuáles fueron las principales medidas adoptadas, conocer la literatura científica al respecto, reseñar algunos casos relevantes en museos europeos, asiáticos y americanos, y señalar los retos y las dinámicas impulsadas en el periodo postpandémico. El texto nace de una atenta revisión bibliográfica para delimitar de qué modo el ámbito museístico debe reconfigurar su presencia atendiendo a tres factores: tecnología, patrimonio y público. Un panorama en que la presencia de las redes sociales, el auge de las exposiciones en línea y otros recursos digitales se consideran fundamentales.

Abstract Introduction. Corn is one of the oldest known food grains. With climate change and frequent and severe droughts, the water available in the soil will be considerably reduced. Water deficit affects maize crop development to varying degrees, and sensitivity to this stress varies at different development stages. Objective. To identify the phenological stages most sensitive to water deficit in maize. Materials and methods. The experiment was conducted during two growing seasons in 2020 and 2021 in El Ejido, Los Santos province, Panama, under semi-controlled conditions in the greenhouse facilities of the Instituto Coronel Segundo de Villarreal. The commercial corn hybrid ADV-9293 was used and agronomic management was carried out according to the recommendations of the Institute for Agricultural Innovation of Panamá (IDIAP). Plant height, leaf length and width, stem diameter, biomass and yield components, such as number of rows per ear, number of grains per row and 100-grain mass, were determined throughout the crop cycle. Soil moisture was also determined by the gravimetric method. Water deficit at different stages was generated by drought simulation. Results. The grain yields of the control were higher than the different treatments evaluated with 12.83 t ha-1, followed by the treatment with grain filling stress with 10.31 t ha-1. Two periods were determined to be more sensitive to water deficit; these were the stages from 20 to 35 and 40 to 55 days after planting. Water deficit in the different phenological stages of the crop had a negative impact on the relative chlorophyll content. Conclusion. The pre-flowering and flowering stages were more sensitive to water deficiency in maize.

Resumen Introducción. El maíz es uno de los granos alimenticios más antiguos conocido. Con el cambio climático y las sequías severas y frecuentes, se reducirá en gran medida el agua disponible en el suelo. El déficit hídrico afecta en diversos grados el desarrollo del cultivo de maíz y la sensibilidad a este estrés varía en las diferentes etapas de desarrollo. Objetivo. Identificar las etapas fenológicas más sensibles al déficit hídrico en el cultivo de maíz. Materiales y métodos. El experimento se realizó durante dos ciclos en los años 2020 y 2021 en El Ejido, Provincia de Los Santos, Panamá. Se desarrolló bajo condiciones semicontroladas en la casa de cultivo del Instituto Coronel Segundo de Villarreal. Se utilizó el híbrido de maíz comercial ADV-9293. El manejo agronómico se realizó según las recomendaciones del Instituto de Innovación Agropecuaria de Panamá (IDIAP). Durante todo el ciclo del cultivo, se determinaron las variables altura de planta, largo y ancho de hojas, diámetro del tallo, biomasa y los componentes del rendimiento como número de hileras por mazorca, número de granos por hilera y peso de cien granos. También, se determinó la humedad del suelo por el método gravimétrico. El déficit hídrico en distintas etapas se generó a través de la simulación de sequía. Resultados. El rendimiento de grano del testigo superó los diferentes tratamientos evaluados con 12,83 t ha-1, seguido por el tratamiento con estrés en el llenado de grano con 10,31 t ha-1. Se determinaron dos períodos más sensibles al déficit hídrico; los cuales son las etapas comprendidas desde los 20 a 35 y 40 a 55 dds. El déficit hídrico, durante las diferentes etapas fenológicas del cultivo, tuvo un impacto negativo en el contenido relativo de clorofilas. Conclusión. Las etapas de prefloración y floración resultaron más sensibles a la deficiencia hídrica en el cultivo del maíz.

Abstract This research examines the relationship between the transmission of entrepreneurial orientation (EO) and socio-emotional wealth (SEW), and their implications for family firms' innovation. To achieve this, a single case study was conducted on a Spanish family business through interviews and document review. Data were analyzed using thematic and critical incident analysis. The findings of the case study underscore that the relationship between entrepreneurial orientation and socio-emotional wealth is intricate and has significant implications for innovation. The dynamic relationship between entrepreneurial orientation and socio-emotional wealth is characterized by a mutually reinforcing symbiosis, which contributes to ensure the long-term survival of the analyzed family business.

Resumen Esta investigación examina la relación entre la transmisión de la orientación emprendedora (OE) y la riqueza socioemocional (SEW), así como sus implicaciones para la innovación dentro de las empresas familiares. Para ello, se llevó a cabo un estudio de caso único sobre una empresa familiar española mediante entrevistas y revisión documental. Los datos fueron analizados utilizando análisis temático y análisis de incidentes críticos. Los hallazgos de este estudio de caso destacan que la relación entre la Orientación Emprendedora y la Riqueza Socioemocional en empresas familiares es compleja y posee importantes implicaciones para la innovación. La interrelación dinámica entre la orientación emprendedora y la riqueza socioemocional se caracteriza por una simbiosis que se refuerza mutuamente, lo que contribuye a garantizar la supervivencia a largo plazo de la empresa familiar analizada.

Abstract Open innovation proposes information exchanges between the company and external stakeholders to improve the results of innovation processes. In this work we adopt the open innovation approach to enhance a company’s innovation performance by implementing co-creation practices with customers. To do this, we rely on design thinking, a framework focusing on the relationship with end users, and adopt action research as a research methodology. The research is carried out in a service SME, characterised by being knowledge-intensive and offering innovative and customised services with high value added. We identify several co-creation practices and examine their degree of adoption by the company and prioritise those that should be implemented. For academics, this work contributes to increase the stock of knowledge on co-creation in the context of SMEs. The study offers valuable insights to practitioners into how an innovation framework that incorporates co-creation practices helps to improve the firm's innovation results, while presenting a methodology that facilitates collaboration with researchers on innovation projects.

Resumen La innovación abierta propone el intercambio de información entre la empresa y su entorno externo para mejorar los resultados de su proceso de innovación. En este trabajo adoptamos el enfoque de la innovación abierta para mejorar los resultados de innovación de una empresa mediante la aplicación de prácticas de co-creación con los clientes. Para ello, nos basamos en design thinking, un marco de trabajo centrado en la relación con el usuario final, y adoptamos la investigación-acción como metodología de investigación. La investigación se lleva a cabo en una PYME de servicios, caracterizada por ser intensiva en conocimiento y ofrecer servicios innovadores y personalizados de alto valor añadido. Se identifican una serie de prácticas de co-creación, se examina su grado de adopción por parte de la empresa y se priorizan las que deben ser implementadas. Este trabajo es de interés para el ámbito académico porque cubre brechas de investigación relacionadas con la co-creación en el contexto de una PYME y el uso de la metodología de investigación-acción en la gestión de la innovación. Para los profesionales, por una parte ofrece conocimientos sobre un nuevo marco de innovación que incorpora prácticas de co-creación para mejorar sus resultados, y por otra presenta una metodología que facilita la colaboración con investigadores en proyectos de innovación.

Abstract The importance of humanitarian social intervention in situations of vulnerability in Ecuador is a topic that is extremely important to discuss since human solidarity is derived from it to help people who are going through some type of crisis, the objective of this article. It is to publicize the help that is provided to people or groups who are going through extreme problems and difficulties. The purpose of carrying out research focused on humanitarian social intervention in vulnerable environments in Ecuador is to offer information and knowledge through a bibliographic analysis. This will allow professionals and organizations involved in social intervention to design and apply effective strategies to address the needs of vulnerable people. Research can be key to identifying the underlying causes of vulnerability, evaluating the effectiveness of current interventions and proposing new solutions to improve the quality of life of those affected. This study seeks to determine the impact of humanitarian social interventions in vulnerable contexts in Ecuador and highlight their relevance. It is hoped that this analysis will not only inform current practices, but also inspire innovation and promote collaboration among diverse actors involved in caring for vulnerable populations.

Resumen La importancia de la intervención social humanitaria en situaciones de vulnerabilidad en Ecuador es un tema del cual se de suma importancia discutir ya que de este se deriva la solidaridad humana en ayuda de las personas que están atravesando algún tipo de crisis, el objetivo de este artículo es dar a conocer la ayuda que se brinda a las personas o grupos que están pasando por problemas y dificultades extremas. El propósito de llevar a cabo una investigación centrada en la intervención social humanitaria en entornos vulnerables en Ecuador es ofrecer información y conocimientos a través de un análisis bibliográfico. Esto permitirá a los profesionales y organizaciones implicadas en la intervención social diseñar y aplicar estrategias efectivas para atender las necesidades de las personas vulnerables. La investigación puede ser clave para identificar las causas subyacentes de la vulnerabilidad, evaluar la eficacia de las intervenciones actuales y proponer nuevas soluciones para mejorar la calidad de vida de los afectados. Este estudio busca determinar el impacto de las intervenciones sociales humanitarias en contextos vulnerables en Ecuador y destacar su relevancia. Se espera que este análisis no solo informe las prácticas actuales, sino que también inspire la innovación y promueva la colaboración entre diversos actores involucrados en la atención a poblaciones vulnerables.

Resumo: Este artigo apresenta uma reflexão sobre como o conhecimento explícito e tácito teve impacto no desenvolvimento de inovações em sete empresas do setor alimentar costarriquenho pertencentes à Câmara Costarriquenha da Indústria Alimentar (CACIA). O que foi dito acima é do interesse de derivar implicações para o sistema educativo costarriquenho. A investigação realizada baseouse em um enfoque qualitativo, através da aplicação de entrevistas semiestruturadas a agentes de cada uma das empresas. Os resultados mostram que ambas as formas de conhecimento desempenharam um papel central na consecução de diversas inovações em cada uma das organizações. Ao mesmo tempo, derivam seis implicações para o sistema educativo, na sua condição de instituição socializadora e construtora de conhecimentos e capacidades, para uma sociedade que exige pessoas inovadoras.

Resumen: En este artículo, se presenta una reflexión sobre cómo el conocimiento explícito y tácito tuvo incidencia en el desarrollo de innovaciones en siete empresas del sector alimentario costarricense pertenecientes a la Cámara Costarricense de la Industria Alimentaria (CACIA). Lo anterior con el interés de derivar implicaciones para el sistema educativo costarricense. La investigación realizada se sustentó en un enfoque cualitativo, por medio de la aplicación de entrevistas semiestructuradas a agentes en cada una de las empresas. En los resultados, se constata que ambas formas de conocimiento jugaron un papel central en la consecución de diversas innovaciones, en cada una de las organizaciones. A la vez que derivan seis implicaciones para el sistema educativo, en su condición de institución socializadora y constructora de conocimientos y capacidades, para una sociedad que demanda personas innovadoras.

Abstract: This article offers a reflection on the impact of explicit and tacit knowledge on the development of innovations in seven Costa Rican food industry companies that are members of the Costa Rican Chamber of Food Industry (CACIA, in Spanish). This was done with the purpose of deriving implications for the Costa Rican educational system. The research was a qualitative approach, based on the application of semi-structured interviews with officers in each of the companies. The results show that both forms of knowledge play a central role in the achievement of various innovations in each of the organizations. The results also suggest six implications for the education system as a socializing institution and a builder of knowledge and skills for a society that demands innovative people.