ABSTRACT The objective was to analyze the social determinants of health in Angola. This is a documentary, exploratory and quantitative research, carried out with data from the 2015-2016 Multiple Indicators and Health Survey in Angola. The analyzed variables were: access to drinking water sources; appropriate sanitary facilities; access to electricity; educational level; access to jobs; child mortality rate; prenatal consultations; and vaccination coverage. It was observed that 45.2% of households do not have access to adequate water sources for drinking; 52.9% use inappropriate sanitation facilities, mainly in rural areas; 31% of men aged 15 to 49 were unemployed; 42% of households had access to electricity; 22% of women and 8% of men aged 15 to 49 have never attended school; the estimated infant mortality rate was 44 deaths for every 1000 live births; 44.1% of pregnant women with lower socioeconomic status did not undergo any prenatal consultation; 18.3% of children aged 12 to 23 months and 21% aged 24 to 35 months did not receive any vaccine. It is concluded that there are large gaps in access to social determinants of health, highlighting the need for government efforts in partnership with international organizations to improve the population’s health conditions.

RESUMO Objetivou-se analisar os fatores determinantes sociais da saúde em Angola. Trata-se de uma pesquisa documental, exploratória e quantitativa, realizada com dados do Inquérito de Indicadores Múltiplos e de Saúde 2015-2016 de Angola. Foram analisadas as variáveis: acesso a fontes de água para beber; instalações sanitárias apropriadas; acesso à eletricidade; nível educacional; acesso a empregos; taxa de mortalidade infantil; consultas pré-natais; e cobertura vacinal. Observou-se que 45,2% dos agregados familiares não têm acesso a fontes de água apropriada para beber; 52,9% utiliza instalações sanitárias não apropriadas, principalmente nas áreas rurais; 31% dos homens de 15 a 49 anos estavam desempregados; 42% dos agregados familiares possuíam acesso à eletricidade; 22% das mulheres e 8% dos homens de 15 a 49 anos nunca frequentaram a escola; a estimativa da taxa de mortalidade infantil foi de 44 mortes para cada 1000 nascidos-vivos; 44,1% das gestantes com menor nível socioeconômico não realizaram nenhuma consulta pré-natal; 18,3% das crianças de 12 a 23 meses e 21% de 24 a 35 meses não receberam nenhuma vacina. Conclui-se que existem grandes lacunas no acesso a determinantes sociais da saúde, evidenciando a necessidade de esforços governamentais em parceria com organismos internacionais para melhorar as condições de saúde da população.

Resumen Introducción: Este estudio experimental, centrado en el desarrollo cognitivo infantil y su relación con la nutrición, analizó las asociaciones semánticas de niños y niñas de nueve diferentes ciudades en Colombia con edades comprendidas entre 6 y 13 años (N = 454). Método: Esta investigación tiene un diseño exploratorio, descriptivo correlacional transeccional, basado en una tarea de asociación libre discreta, que consistió en instruir a los participantes para que respondieran a una palabra crítica con las cinco primeras palabras que pensaran, abarcando 100 palabras de alimentos en español y 20 marcas de productos alimenticios. Resultados: Se muestra el valor J por edad, estrato socioeconómico, género y grado académico. Las similitudes significativas (p-value < .001) entre las distribuciones de palabras críticas y las emitidas con mayor frecuencia (f) destacaron la influencia hedónica en las preferencias alimenticias de los niños. En efecto, se identificaron 20 descriptores frecuentes del placer o tópicos hedónicos en el consumo de alimentos, sobresaliendo términos como dulce (f =234) y rico (f = 104). Conclusiones: Se observó una interpretación errónea de la población sobre el significado del concepto saludable (f = 52) en relación con la alimentación. El análisis de las asociaciones semánticas para las 20 principales marcas de alimentos infantiles, respaldado por el índice de Jaccard, proporcionó diez conexiones significativas por cada marca. Estos hallazgos sugieren implicaciones importantes para entender los procesos de aprendizaje organoléptico de alimentos y productos en la infancia, subrayando la necesidad de abordar las percepciones hedónicas y promover una comprensión más precisa de los conceptos relacionados con la salud en el contexto alimentario infantil.

Abstract Introduction: This experimental study focuses on the cognitive development of children and its association with nutrition. The semantic associations of boys and girls aged 6-13 years from nine different cities in Colombia (N = 454) were analyzed. Method: The design is exploratory and descriptive correlational cross-sectional. The study utilized a discrete free association task, instructing participants to respond to a critical word with the first five words that came to mind. The task covered 100 Spanish food words and 20 brands of food products. Results: J-values are presented by age, socioeconomic status, gender and grade level. The identification of significant similarities (p-value < .001) between the distributions of critical words and the most frequently emitted (f), highlighted the hedonic influence on children’s food preferences, identifying 20 frequent descriptors of pleasure or hedonic topics in food consumption, with terms such as sweet (f = 234) and rich (f = 104) standing out. Conclusions: The study observed a population misinterpretation of the concept healthy (f = 52) in relation to food. The analysis of semantic associations for the top 20 infant food brands, supported by Jaccard’s index, revealed ten significant connections for each brand. These findings suggest important implications for understanding organoleptic food and product learning processes in childhood. The study emphasizes the importance of addressing hedonic perceptions and fostering a more precise understanding of health-related concepts within the realm of children’s dietary preferences.

Resumen La desnutrición infantil constituye un desafío de gran importancia en el ámbito de la salud pública. El objetivo de la investigación fue evaluar la influencia de los factores sociales y culturales en el estado nutricional en niños menores ecuatorianos de 2 años, en la ciudad de Portoviejo, Provincia de Manabí, durante el año 2023. Se realizó una investigación prospectiva, descriptiva, transversal y observacional. La población pediátrica incluyó 169 menores de dos años, cuyas madres proporcionaron los datos pertinentes. Los factores sociales predominantes fue el nivel educativo del cuidador del niño comprendida entre 7 a 12 años de estudios con la presencia de casos de desnutrición crónica en un 83,9%; además, la limitada contribución financiera del progenitor para la alimentación del infante con casos de desnutrición aguda en un 88,6%. Dentro de los factores culturales, se encontró que los niños con esquema de vacunación incompleto presentaban desnutrición crónica con un 88,7%, la falta de los controles prenatales, al igual que la inasistencia al primer control prenatal antes del quinto mes con casos de desnutrición aguda en un 95,5%; además, se evidenció que la estimulación para la ingesta de alimentos y la falta de práctica de la lactancia materna exclusiva con la presencia de desnutrición crónica en los menores, con un 98,4% y un 96,8%, respectivamente. En este entorno, el estado nutricional de mayor tendencia fue la desnutrición crónica con un 34,3%. Además, se identificó una asociación significativa de relación de dependencia (p<0,05) entre los factores sociales, culturales y el estado nutricional.

Abstract Child malnutrition constitutes a challenge of great importance in the field of public health. The objective of the research was to evaluate the influence of social and cultural factors on the nutritional status in Ecuadorian children under 2 years of age in the city of Portoviejo, Province of Manabí, during the year 2023. A prospective, descriptive, crooss-sectional and observational research was carried. The pediatric population included 169 children under two years of age, whose mothers provided the relevant data. The predominant social factors were the educational level of the child's caregiver, ranging from 7 to 12 years of education, with the presence of cases of chronic malnutrition in 83.9%; in addition, the limited financial contribution of the parent to feeding the infant with cases of acute malnutrition in 88.6%. Within the cultural factors, it was found that children with an incomplete vaccination presented chronic malnutrition with 88.7%, the lack of prenatal check-ups, as well as non-attendance at the first prenatal check-up before the fifth month with cases of malnutrition acute in 95.5%; Furthermore, it was evidenced that the stimulation of food intake and the lack of practice of exclusive breastfeeding with the presence of chronic malnutrition in minors, with 98.4% and 96.8%, respectively. In this environment, the most trending nutritional status was chronic malnutrition with 34.3%. In addition, a significant association of dependency relationship (p<0.05) was identified between social and cultural factors and nutritional status.

RESUMEN Introducción: La duración de la lactancia materna es crucial para la salud infantil, sin embargo, la prevalencia ha disminuido en los últimos años, situando a los niños en una población de riesgo. Objetivo: Determinar los factores asociados a la duración de la lactancia materna en niños menores de 2 años en el Perú 2021-2022. Metodología: Estudio analítico transversal, a través del análisis secundario de datos de la Encuesta Demográfica y de Salud Familiar (ENDES) del año 2021 y 2022. El tamaño muestral fue de 4951 niños/niñas con sus respectivas madres. Se evaluaron factores infantiles y maternos utilizando el Estadístico F corregida para el análisis bivariado con una significancia estadística p<0,05 y un intervalo de confianza al 95%. Finalmente, para medir la asociación se calculó la razón de prevalencia cruda (RPc) y la razón de prevalencia ajustada (RPa) mediante la Regresión de Poisson con varianza robusta. Resultados: El 85,3% tuvo una duración de 0-6 meses y solo el 14,7% tiene una duración hasta los 23 meses. El no contacto piel a piel precoz bebe-madre (p <0,01) (RPa 1,19) y el consumo de bebidas diferentes a la leche materna los primeros 3 días de nacido (p <0,01) (RPa 0,66) se asociaron con una duración hasta los 6 meses de lactancia materna. Las madres adolescentes tuvieron un 30,7% de duración de lactancia materna de 6 meses (p<0,01) (RPa 2,49), por el contrario, el lugar de residencia rural, el grado no superior y un menor ingreso económico permiten una lactancia materna por más de 6 meses. Discusión: Los resultados asocian no recibir contacto piel a piel precoz bebe-madre, edad materna igual o menor de 18 años, grado superior, lugar de residencia urbano y mayor ingreso económico con una menor duración de lactancia materna en niños menores de 2 años.

ABSTRACT Introduction: The duration of breastfeeding is crucial for child health; however, the prevalence has decreased in recent years, placing children in a population at risk. Objective: To determine the factors associated with the duration of breastfeeding in children under 2 years of age in Peru 2021-2022. Methodology: Cross-sectional analytical study, through the secondary analysis of data from the Demographic and Family Health Survey (ENDES) of 2021 and 2022. The sample size was 4951 children with their respective mothers. Infant and maternal factors were evaluated using the F-statistic corrected for bivariate analysis with a statistical significance of p<0.05 and a 95% confidence interval. Finally, to measure the association, the crude prevalence ratio (cPR) and the adjusted prevalence ratio (aPR) were calculated using Poisson regression with robust variance. Results: 85.3% had a duration of 0-6 months and only 14.7% had a duration of up to 23 months. Early baby-mother skin-to-skin non-contact (p <0.01) (aPR 1.19) and consumption of beverages other than breast milk in the first 3 days of birth (p <0.01) (aPR 0.66) were associated with a duration of breastfeeding up to 6 months. Adolescent mothers had a 30.7% duration of breastfeeding of 6 months (p<0.01) (aPR 2.49), on the contrary, the place of rural residence, the non-higher grade and a lower economic income allow breastfeeding for more than 6 months. Discussion: The results were associated with not receiving early skin-to-skin contact between the baby and the mother, maternal age equal to or less than 18 years, higher grade, urban place of residence and higher economic income with a shorter duration of breastfeeding in children under 2 years of age.

ABSTRACT Respiratory syncytial virus (RSV) infections constitute a significant cause of morbidity, hospitalization, school and work absenteeism, as well as mortality worldwide, including in Paraguay. Currently, tools for RSV prevention are available. In 2012, Paraguay approved the use of palivizumab (MedImmune, USA), a monoclonal antibody produced through recombinant DNA technology. This antibody is administered in 5 doses, every 30 days and is indicated in infants born prematurely and those with cardiopulmonary disorders. Furthermore, a novel tool for RSV prevention has recently become available. Nirsevimab, a long-acting monoclonal antibody specific to the prefusion conformation of the F protein, has been approved by both the European Medicines Agency (EMA) and the Food and Drug Administration (FDA). This monoclonal antibody is indicated for the prevention of acute lower respiratory tract infections caused by RSV in newborns and infants born during or entering their first RSV season, as well as in premature infants and infants up to 24 months of age who remain vulnerable to severe RSV disease during their second RSV season. After analyzing the epidemiological situation of RSV in our country and evaluating the evidence of efficacy, efficiency, and effectiveness of this monoclonal antibody, academic institutions, scientific societies, and non-governmental and governmental organizations developed consensus guidelines on a new prevention alternative for the prevention of RSV infections, suggesting the incorporation of Nirsevimab in children under 12 months of age before their first RSV season and replacing Palivizumab. The new monoclonal has the potential to change the panorama of RSV infections in infants and produce an impact on the reduction of infant mortality and morbidity reducing the burden on the health system by decreasing hospital bed occupancy both in wards and in intensive care units, as well as the decrease in the burden on caregivers, physicians and health care providers.

RESUMEN Las infecciones por el VSR en constituyen una causa importante de morbilidad, hospitalización, ausentismo escolar y laboral, así como de mortalidad, en el mundo, así como en el Paraguay.En la actualidad, existen herramientas para la prevención del VSR. En el año 2012, el Paraguay, ha incorporado el palivizumab (MedImmune, EE. UU.), anticuerpo monoclonal, producido por tecnología de DNA recombinante. Este anticuerpo se administra en 5 dosis, cada 30 días y está indicado en lactantes nacidos prematuros y aquellos con trastornos cardiopulmonares. Por otro lado, actualmente se cuenta con una nueva herramienta para la prevención del VSR. El anticuerpo monoclonal de vida media prolongada Nirsevimab, específico para la conformación de prefusión de la proteína F, aprobado por EMA y FDA. Este monoclonal, está indicado para la prevención de las Infecciones respiratorias agudas bajas, causada por VSR en recién nacidos y lactantes nacidos durante o al ingresar a su primera temporada de VSR, en prematuros y lactantes hasta los 24 meses de edad que siguen siendo vulnerables a la enfermedad grave por VSR durante su segunda temporada de VSR. Luego de analizar la situación epidemiológica del VSR en el país así como la evidencia de eficacia, eficiencia y efectividad de este monoclonal; instituciones académicas, sociedades científicas, organizaciones no gubernamentales y gubernamentales se reunieron y elaboraron un consenso interinstitucional para la prevención de las infecciones por VSR, sugiriendo la incorporación del Nirsevimab, en menores de 12 meses de edad antes de su primera temporada de VSR y en reemplazo del Palivizumab, debido a que el nuevo monoclonal tiene el potencial de cambiar el panorama de las infecciones por VSR en el lactante y producir un impacto en la reducción la mortalidad y morbilidad infantil; reduciendo la carga al sistema de salud, en lo que se refiere a la disminución de la ocupación de camas hospitalarias tanto en sala como en unidades de cuidados intensivos, así como la disminución de la carga para los cuidadores, médicos y proveedores de atención médica y la mortalidad infantil.

Resumen Esta revisión narrativa de la literatura pretende describir la importancia de la depresión posparto (DPP), intentando identificar la mejor manera de detectarla y los beneficios de realizar un manejo oportuno. La DPP es un trastorno del estado de ánimo que afecta a las mujeres después de dar a luz. Se caracteriza por síntomas como estado de ánimo deprimido, pérdida de interés o placer, cambios de peso, trastornos del sueño, falta de energía, dificultad para concentrarse, sentimientos de culpa o inutilidad, y pensamientos suicidas. Se estima que afecta al 6,9 a 12,9% de las mujeres en los países desarrollados y hasta el 20% en los de bajos ingresos. La etiología de la DPP involucra una interacción de factores hormonales, neuroendocrinos, genéticos, neuroinflamatorios y psicosociales; además, se han identificado diversos factores de riesgo, como antecedentes familiares de depresión, estrés, falta de apoyo social y problemas de salud del bebé. La detección se puede realizar mediante escalas rápidas, como la Escala de Depresión Posparto de Edimburgo. Su manejo se basa en diferentes tipos de psicoterapia, como la terapia cognitivo-conductual, la terapia de apoyo e interpersonal, además de medidas farmacológicas como los antidepresivos inhibidores selectivos de la recaptación de serotonina (ISRS) o los inhibidores de la recaptación de serotonina y noradrenalina (IRSN), u otras terapias como la brexanolona o los estrógenos.

Abstract This narrative review of the literature aims to describe the importance of postpartum depression (PPD), trying to identify the best way to detect it and the benefits of timely management. PPD is a mood disorder that affects women after giving birth. It is characterized by symptoms such as depressed mood, loss of interest or pleasure, weight changes, sleep disorders, lack of energy, difficulty concentrating, guilt or worthlessness, and suicidal thoughts. It is estimated that it affects between 6.9% and 12.9% of women in high-income countries and up to 20% in low-income countries. The etiology of PPD involves an interplay of hormonal, neuroendocrine, genetic, neuroinflammatory, and psychosocial factors. Furthermore, various risk factors have been identified, including a family history of depression, stress, lack of social support, and health problems in the infant. Detection can be done using rapid scales like the Edinburgh Postnatal Depression Scale. Its management is based on different types of psychotherapy, namely cognitive behavioral therapy, supportive and interpersonal therapy, as well as pharmacological measures including serotonin reuptake inhibitor or serotonin and noradrenaline reuptake inhibitor antidepressants, and other therapies like brexanolone or estrogens.

Abstract Introduction: Maternal recognition of special health needs of premature babies is essential, given the importance of early stimuli after discharge to strengthen child development. Objective: To identify premature newborns with potential factors for the development of special health needs and describe maternal recognition of these factors. Materials and methods: Qualitative and quantitative study, performed using a triangulation method, with concomitant incorporation of data, included to analysis Chi-square test (p<0.05) for quantitative data and interpretation of meanings for qualitative. Variables: Birth weight, gestational age, Apgar score, complications, and length of hospital stay from 951 records of hospitalized premature infants; 18 mothers were interviewed during hospitalization, 15 days after discharge at home, 30 days after this at-home visit and at the age of 6 months of the child, by telephone, in Southern Brazil. Results: Identified as potential factors: Extreme prematurity and/or very premature, low birth weight, complications, and prolonged hospitalization. With the incorporation of the data, the relevance of these factors for children at risk of changes in development and behavior was verified. Mothers described their children as having healthy development but recognized prematurity is a factor that predisposes to new hospitalizations, and perinatal factors and those related to hospitalization contribute to the development of special health needs. Conclusion: The importance of early identification of factors that enhance the development of special health needs is understood to initiate the necessary stimuli to strengthen child development.

Resumen Introducción: El reconocimiento materno de las necesidades especiales de salud de los bebés prematuros es esencial, por la importancia de los estímulos tempranos después del alta para fortalecer el desarrollo infantil. Objetivo: Identificar a los recién nacidos prematuros con factores potenciales para el desarrollo de necesidades especiales de salud y describir el reconocimiento materno de estos factores. Materiales y métodos: Estudio cualitativo y cuantitativo, realizado mediante un método de triangulación, con incorporación concomitante de datos, incluido en el análisis del test de Chi-cuadra-do (p<0,05) para los datos cuantitativos, y la interpretación de significados para los cualitativos. Variables: Peso al nacer, edad gestacional, puntuación de Apgar, complicaciones y duración de la estancia hospitalaria a partir de 951 registros de niños prematuros hospitalizados; 18 madres fueron entrevistadas durante la hospitalización, 15 días después del alta en el domicilio, 30 días después de esta visita domiciliaria y a la edad de 6 meses del niño, por teléfono, en el sur de Brasil. Resultados: Se identificaron como factores potenciales: prematuridad extrema y/o muy prematuro, bajo peso al nacer, complicaciones y hospitalización prolongada. Con la incorporación de los datos se verificó la relevancia de estos factores para los niños en riesgo de cambios de desarrollo y comportamiento. Las madres describieron a sus hijos con un desarrollo saludable, pero reconocieron que la prematuridad es un factor que predispone a nuevas hospitalizaciones, y los factores perinatales y los relacionados con la hospitalización contribuyen al desarrollo de necesidades especiales de salud. Conclusión: Se entiende que la importancia de la identificación temprana de los factores que mejoran el desarrollo de las necesidades especiales de salud permite el inicio de los estímulos necesarios para fortalecer el desarrollo infantil.

Resumo Introdução: O reconhecimento materno das necessidades especiais de saúde dos recém-nascidos prematuros é essencial devido à importância da estimulação precoce após a alta para fortalecer o desenvolvimento infantil. Objetivo: Identificar bebês prematuros com fatores potenciais para o desenvolvimento de necessidades especiais de saúde e descrever o reconhecimento materno desses fatores. Materiais e métodos: Estudo qualitativo e quantitativo, realizado por meio de um método de triangulação, com incorporação concomitante de dados, incluindo a análise do teste qui-quadrado (p < 0,05) para dados quantitativos e interpretação de significados para dados qualitativos. Variáveis: Peso ao nascer, idade gestacional, escore de Apgar, complicações e tempo de permanência hospitalar de 951 registros de bebês prematuros hospitalizados; 18 mães foram entrevistadas durante a hospitalização, 15 dias após a alta no domicílio, 30 dias após essa visita domiciliar e aos 6 meses de idade do bebê, por telefone, no sul do Brasil. Resultados: Foram identificados como fatores potenciais: prematuridade extrema e/ou muito pré-termo, baixo peso ao nascer, complicações e hospitalização prolongada. A incorporação dos dados verificou a relevância desses fatores para crianças com risco de alterações no desenvolvimento e no comportamento. As mães descreveram seus filhos como tendo um desenvolvimento saudável, mas reconheceram que a prematuridade é um fator predisponente para novas hospitalizações, e que fatores perinatais e relacionados à hospitalização contribuem para o desenvolvimento de necessidades especiais de saúde. Conclusões: Entende-se a importância da identificação precoce de fatores que aumentam o desenvolvimento de necessidades especiais de saúde para iniciar os estímulos necessários a fim de fortalecer o desenvolvimento infantil.

Abstract: Preterm infants, especially those of lower gestational age (GA), are at high risk of hospital readmission in the early years. Objective: To describe the frequency and characteristics of readmissions in preterm infants younger than 32 weeks of GA or weighing less than 1500 g (< 32w/< 1500 g) at 2 years post-discharge from neonatology. Patients and Method: Retrospective observational study of a cohort of newborns < 32w/< 1500 g discharged from a public health care center (2009-2017). The frequency, time of occurrence, risk factors, causes, and severity of hospital readmissions were analyzed. The respective perinatal characteristics and subsequent readmissions were described. The Ethics Committee approved the data collection protocol. Results: 989 newborns < 32w/< 1500 g were included; 410 (41.5%) were readmitted at least once before the age of 2 years, equivalent to 686 episodes (1.7/child); 129 children (31.4%) were admitted to the Pediatric Intensive Care Unit (PICU), with a mean length of stay of 7.7 days. The greatest risk for hospital readmission was during the first 6 months post-discharge. The main cause was respiratory (70%) and respiratory syncytial virus was the most frequent germ. The risk factors associated with readmission due to respiratory causes were bronchopulmonary dysplasia (BPD) (OR: 1.73; 95%CI: 1.26-2.37) and number of siblings (OR: 1.18; 95%CI: 1.04-1.33). Conclusions: Newborns < 32s/< 1500 g are at high risk of hospital readmission due to respiratory causes and PICU admission in the first months post-discharge; BPD and number of siblings were the main risk factors.

Resumen: Los prematuros, especialmente aquellos de menor edad gestacional (EG), presentan alto riesgo de rehospitalización en los primeros años. Objetivo: Describir la frecuencia y características de las rehospitalizaciones en prematuros menores de 32 semanas de EG o menores de 1500 g (< 32s/< 1500 g) a 2 años post alta de neonatología. Pacientes y Método: Estudio observacional retrospectivo de una cohorte de < 32 s/< 1500 g egresados de un centro asistencial público (2009-2017). Se investigó la frecuencia, momento de ocurrencia, factores de riesgo, causas y severidad de las rehospitalizaciones. Se describen las respectivas características perinatales y las subsecuentes rehospitalizaciones. El Comité de Ética aprobó el protocolo de recolección de datos. Resultados: Se incluyeron 989 < 32s/< 1500 g; 410 (41,5%) fueron rehospitalizados al menos 1 vez antes de los 2 años, equivalente a 686 episodios (1,7/niño); 129 niños (31,4%) ingresaron a la Unidad de Cuidados Intensivos Pediátricos (UCIP), con una estadía media de 7,7 días. Los momentos de mayor riesgo fueron los primeros 6 meses post alta. La principal causa fue respiratoria (70%) siendo el virus respiratorio sincicial el germen más frecuente. Los factores de riesgo asociados a rehospitalización de causa respiratoria fueron la displa- sia broncopulmonar (DBP) (OR = 1,73; IC95%: 1,26-2,37) y el número de hermanos (OR = 1,18; IC95%: 1,04-1,33). Conclusiones: Los < 32s/< 1500 g tienen alto riesgo de rehospitalización de causa respiratoria y de ingresar a UCIP en los primeros meses post alta, siendo la DBP y el número de hermanos los principales factores de riesgo.

BACKGROUND. The infant mortality rate (IMR) (24 per 1 000 live births) remains high in South Africa (SA), well above the recommended sustainable development goal (SDG) 3 of 12 deaths per 1 000 live births. High infant mortality is a poor indicator of the health of a population and will hamper attainment of the SDGs. OBJECTIVES. To investigate the trends and distribution patterns of IMR between 2007 and 2016 and its association with HIV-positive pregnant mothers in SA. METHODS. This study used a cross-sectional study design by analysing secondary data on infant mortality from the 2007 and 2016 Statistics South Africa Community Surveys (CSs), as well as data from the 2007 National Antenatal Sentinel HIV and Syphilis Prevalence Survey. (Antenatal HIV Sentinel Survey - ANCHSS). Line charts with descriptive statistics were used to detail trends in IMRs, and multiple logistic regression models were used to identify risk factors for infant mortality in the 2007 and 2016 CS datasets. Spearman's rank-order correlation (rho) was used to correlate infant mortality with data from the 2007 ANCHSS. All analyses were performed with Stata version 16.0. RESULTS. A total sample of 87 805, comprising 43 922 males and 43 883 females, was included in the analysis. The results revealed a decline in IMR from 55 deaths per 1 000 live births in 2007 to 32 in 2016. Overall, there was a significant decrease in the mortality rate from 2007 to 2016. The infant mortality proportions by province showed KwaZulu-Natal Province having the highest IMR (17.5 deaths per 1 000 live births in 2007 and 6.3 in 2016). Males had a higher IMR (28 deaths per 1 000 live births in 2007 and 17.7 in 2016) compared with females at 26.7 deaths per 1 000 live births in 2007 and 13.8 in 2016. IMR data from the 2007 CS was correlated with the 2007 ANCHSS (28% HIV prevalence in 2007), using Spearman's rank-order correlation, which showed a moderate correlation of 0.58 (p<0.001). CONCLUSIONS. The study findings showed a reduction in the trends of infant mortality between 2007 and 2016 in SA; despite the reduction, health inequalities persist. There is a correlation evident between maternal HIV prevalence and IMR in SA. We recommend the use of disability-adjusted life expectancy in SA to measure population health and introduce robust data sets that can better inform policy.

Resumen: El objetivo del trabajo es analizar la distribución espacial de la mortalidad infantil en áreas geográficas pequeñas y cuantificar el efecto de un conjunto de cofactores que teóricamente se asocian con el comportamiento de la mortalidad infantil, como el acceso a servicios de salud, la falta de acceso a agua en viviendas particulares habitadas, la escolaridad femenina y el tamaño de la población. Se inició con la aplicación de un análisis exploratorio de datos espaciales cuyo propósito fundamental es identificar una serie de patrones de agrupamiento espacial. La metodología utilizada comprendió el ajuste de siete modelos de regresión, seis modelos de regresión espacial que configuran tres tipos de interacción espacial endógena, exógena y de términos de error y un modelo de regresión lineal simple (que se utiliza como base de comparación). El criterio de selección para elegir el modelo que mejor ajusta los datos de mortalidad infantil fue el criterio de información de Akaike (AIC), que proporciona una medida de calidad de ajuste del modelo. Los resultados indican que el efecto directo más importante sobre el comportamiento espacial de la mortalidad infantil proviene de los años promedio de escolaridad femenina, pues el incremento promedio de un año de educación implicaría una reducción de 0.076 puntos porcentuales de la tasa de mortalidad infantil municipal. Se observan resultados similares para las variables de la carencia de acceso a agua y porcentaje de población municipal. Clasificación JEL: J13; C33; I14; R12.

Abstract: The objective of this paper is to analyze the spatial distribution of infant mortality in small geographic areas and to quantify the effect of a set of cofactors that are theoretically associated with the behavior of infant mortality, such as access to health services, lack of access to water in private housing, female schooling, and population size. The study began with the application of an exploratory spatial data analysis whose main purpose is to identify a series of spatial grouping patterns. The methodology used involved fitting seven regression models, six spatial regression models that configure three types of endogenous, exogenous, and error term spatial interaction, and one simple linear regression model (used as a basis for comparison). The selection criterion used to choose the model that best fits the infant mortality data was the Akaike Information Criterion (AIC), which provides a measure of the quality of the model fit. The results indicate that the most important direct effect on the spatial behavior of infant mortality comes from the average years of female schooling since the average increase of one year of education would imply a reduction of 0.076 percentage points in the municipal infant mortality rate. Similar results are observed for the variables of lack of access to water and percentage of municipal population.

Abstract Objective To carry out a narrative review on the use of marketing strategies in child nutrition, as well as potential implications for health professionals and children. Data source Searches were carried out on the PubMed, SciELO, and Google platforms, using the terms “child nutrition” or “industrialized baby food” or “infant formula” or “breast milk” or “breastfeeding” and “marketing”, with original articles, review articles, institutional reports, institutional position documents and websites considered relevant to the topic being analyzed. Data synthesis Children's food marketing started with the industrialization of food and the resulting actions aimed at increasing sales and meeting commercial interests. Since its inception to the present, infant formulas have been the most widely used products, which has impacted breastfeeding practices. International and national institutions, that care for children's health, are searching for strategies to limit the abusive marketing of industrialized children's foods. Marketing strategies interfere with medical knowledge and actions, potentially influencing the guidance provided by pediatricians to families, and finally, compromising healthy eating practices at a critical period in life, with possible long-term effects. Conclusions Health professionals, especially pediatricians, must provide the best care for children and families, and need to maintain the search for quality scientific information, not influenced by conflicts of interest. Updated and critical knowledge on the part of healthcare professionals can curb marketing strategies that aim to influence their actions. nutrition PubMed SciELO platforms formula breast milk “breastfeeding marketing, , “marketing” articles reports analyzed Childrens Children s interests present products institutions childrens foods families finally life longterm long term effects information interest “marketing

ABSTRACT Introduction: Infant mortality is a health phenomenon directly related to the deleterious living conditions of both the infant’s home and adverse socioeconomic and sanitary factors. Objective: To characterize inequalities in infant mortality according to differential living conditions in two populations districts of Santiago de Cuba. Methods: A descriptive, exploratory ecological study was carried out in the municipality of Santiago de Cuba in 1995-1997. The units of analysis were constituted by the areas framed in two populations districts of the city. Results: Bothe population districts were stratified, according to their living conditions, in settlements with less unfavorable and more unfavorable living conditions. Higher infant mortality was estimated in the settlement with more unfavorable living conditions (8.7 deaths per 1000 live births), where asphyxia, anoxia and hypoxia predominated as clinical causes of death and clinical causes reducible for good care at birth. Conclusions: A differential profile of infant mortality, according to living conditions, was identified within the population settlements of the urban districts of Santiago de Cuba. The distinctive risks of infant death were at the expense of the neonatal component, mainly for clinical causes reducible by good care at birth.

RESUMEN Introducción: La mortalidad infantil es un fenómeno sanitario relacionado directamente con las condiciones de vida deletéreas, tanto del hogar del infante como de factores socioeconómicos e higiénico-sanitarios adversos. Objetivo: Caracterizar las desigualdades de la mortalidad infantil, según condiciones diferenciales de vida en dos distritos poblacionales de Santiago de Cuba. Métodos: Se llevó a cabo un estudio descriptivo, de tipo ecológico exploratorio, en el municipio Santiago de Cuba, en el trienio 1995-1997. Las unidades de análisis estuvieron constituidas por las áreas de salud enmarcadas en dos distritos poblacionales de la ciudad. Resultados: Se estratificaron ambos distritos poblacionales, según sus condiciones de vida, en asentamientos con condiciones de vida menos desfavorables y más desfavorables. Se estimó mayor mortalidad infantil en el asentamiento con condiciones de vida más desfavorables (8,7 fallecidos por 1000 nacidos vivos), donde predominaron como causas clínicas de muerte las asfixias, la anoxia e hipoxias y causas clínicas reducibles por buena atención en el parto. Conclusiones: Se identificó un perfil diferencial de mortalidad infantil, según las condiciones de vida, al interior de los asentamientos poblacionales de los distritos urbanos de Santiago de Cuba. Los riesgos distintivos de muerte infantil fueron a expensas del componente neonatal, en lo fundamental por causas clínicas reducibles por buena atención en el parto.

BACKGROUND. Despite global strides to reduce child morbidity and mortality, the number of infant and child deaths from preventable causes in low-and middle-income countries remains unacceptably high. A cost-effective strategy to improve child health outcomes is through child vaccination and subsequent immunisation. Despite free child vaccination in the public healthcare sector in Tanzania, the country's vaccination rates have plateaued and remain concentrated among children from wealthier households. OBJECTIVE. To identify the factors contributing to inequality in childhood vaccination in Tanzania. METHODS. This retrospective study used secondary data from the Tanzania Demographic and Health Survey for 2004/05, 2010 and 2015/16. Inequalities were measured using the Erreygers' corrected concentration indices. These inequalities were then decomposed to gain a deeper understanding of the contributing factors. RESULTS. Child vaccinations are higher among children from wealthier households in Tanzania, and this disparity has intensified over time. Socioeconomic differences in wealth, residential locations, mass media exposure and maternal education have become increasingly important drivers of these inequalities among Tanzanians. CONCLUSIONS. Socioeconomic divisions in Tanzania threaten to perpetuate inequalities in access to healthcare and subsequent health. Child vaccination should be provided equitably to all children regardless of their household's socioeconomic background. Moreover, efforts should be made to address these gaps between the vulnerable and the more privileged groups in society.

BACKGROUND. The positive deviance approach has been used to identify infant and young child feeding (IYCF) practices associated with a reduction in stunting, but this research is limited in South Africa (SA). OBJECTIVE. To identify strategies among positive deviant (PD) caregivers of non-stunted children aged 6 - 18 months that influence infant and young child feeding (IYCF) practices and raise well-nourished children in two informal settlements in Harrismith. METHODS. This study employed a mixed-method design using a PD approach. Demographic questionnaires were administered to 28 purposefully sampled caregiver-child pairs to determine caregiver, child and household characteristics. Socioeconomic scores were obtained from these interviews and used to select six PD and six non-positive deviant (NPD) caregivers for semi-structured qualitative interviews between March and June 2019. RESULTS. Nutritional PD behaviours included consuming 'flesh foods' (meat) more often and practising responsive feeding and family eating. Non-nutritional PD behaviours included coping strategies involving health-seeking behaviour, financial strategy and social capital of caregivers. All caregivers displayed poor breastfeeding practices and an early introduction of solid foods. Primary healthcare nurses were reported to frequently provide breastfeeding advice from outdated prevention of mother-to-child transmission policy. CONCLUSIONS. Poor IYCF practices highlight the need for continued advocacy and promotion of IYCF in SA. Nutritional PD behaviours are key to health promotional messages relayed within the local community where the research was conducted. The presence of nutritional and non-nutritional PD behaviours highlights the need for a multi-sectoral response to addressing stunting and improving IYCF practices.

Abstract Pregnancy represents an opportunity for the health system to diagnose and treat infections that increase maternal, fetal, and neonatal morbidity and mortality. Elimination of maternal-infant transmitted diseases is a priority in the Americas region. Several efforts are taking place to reach this goal by the year 2030. This document gathers the participation of several experts from the Latin American and Caribbean Region within the Latin-American Society of Pediatric Infectious Diseases (SLIPE), presenting a practical guidance adapted to the limitations of our countries, that support the analysis and improvement in interventions to change the management of congenital infection.

Resumen El embarazo representa una oportunidad del sistema de salud para el diagnóstico y tratamiento de afecciones que aumentan la morbilidad fetal y neonatal, y la salud de la mujer gestante, siendo la eliminación de las enfermedades de transmisión materno-infantil una prioridad en la región de las Américas. En esta línea se están llevando a cabo numerosos esfuerzos en la región para alcanzar esta meta para el año 2030. El presente documento reúne la participación de expertos en la Región de América Latina y el Caribe, dentro de la Sociedad Latino-americana de Infectología Pediátrica (SLIPE), brindando una mirada práctica adaptada a las limitaciones de muchos de nuestros países, que nos ayude a analizar las mejores herramientas para detectar posibles momentos estratégicos de intervención y cambio en el manejo de las infecciones congénitas.