Resumen: La influencia de las tecnologías de la información en la educación superior ha facilitado el acceso a la información propiciando casos de ciberplagio. Por lo que este estudio tuvo como objetivo identificar las prácticas y causas del ciberplagio entre personas estudiantes universitarias, analizando diferencias según sexo, edad, tipo de universidad y área profesional de estudio. Se aplicó un cuestionario a 584 estudiantes de una provincia en el centro del Perú. Los resultados indican que las principales formas de ciberplagio incluyen la presentación de trabajos con fragmentos copiados de sitios web y recursos en línea, el uso inadecuado del parafraseo sin respetar la propiedad intelectual y la reproducción de información sin citar las fuentes. Las causas principales se atribuyen tanto a estudiantes (falta de tiempo y desconocimiento de normas de citación) como a docentes (exceso de tareas asignadas y falta de rigor en la evaluación). El análisis por variables muestra diferencias significativas en cuanto a la edad, siendo el estudiantado de 20-22 años quienes más frecuentemente incurren en ciberplagio. Estos hallazgos sugieren la necesidad de abordar las causas subyacentes del plagio académico e implementar medidas preventivas y correctivas en el ámbito universitario para fomentar la ética de la información y la integridad académica.

Resumo: A influência das tecnologias de informação na educação superior tem facilitado o acesso à informação, originando casos de ciberplágio. Portanto, este estudo teve como objetivo identificar as práticas e causas do ciberplágio entre pessoas estudantes universitárias, analisando diferenças segundo sexo, idade, tipo de universidade e área profissional de estudo. Um questionário foi aplicado a 584 estudantes de uma província do centro do Peru. Os resultados indicam que as principais formas de ciberplágio incluem a apresentação de trabalhos com fragmentos copiados de sites e recursos online, o uso inadequado de paráfrases sem respeitar a propriedade intelectual e a reprodução de informações sem citar as fontes. As principais causas são atribuídas tanto aos estudantes (falta de tempo e desconhecimento dos padrões de citação) quanto aos docentes (excesso de tarefas atribuídas e falta de rigor na avaliação). A análise por variáveis mostra diferenças significativas em termos de idade, sendo os estudantes dos 20 aos 22 anos os que mais frequentemente cometem ciberplágio. Estas descobertas sugerem a necessidade de abordar as causas subjacentes ao plágio académico e implementar medidas preventivas e corretivas no ambiente universitário para promover a ética da informação e a integridade académica.

Abstract: The influence of information technologies in higher education has facilitated access to information and has led to cases of cyberplagiarism. The purpose of this study was to identify the practices and causes of cyberplagiarism among university students, analysing the differences according to gender, age, type of university and field of study. A total of 584 students from a province in central Peru were asked to complete a questionnaire. The results show that the main forms of cyberplagiarism are submitting work with fragments copied from websites and online resources, the inappropriate use of paraphrasing without respecting intellectual property and the reproduction of information without citing sources. The main causes are attributed to both students (lack of time and lack of knowledge of citation rules) and teachers (excessive homework and lack of rigour in assessment). The analysis by variables shows significant differences in terms of age, with students aged between 20 and 22 being the most frequent victims of cyberplagiarism. These results suggest the need to address the root causes of academic plagiarism and to implement preventive and corrective measures at university level to promote information ethics and academic integrity.

Abstract Healthcare during the COVID-19 pandemic may have led to the inappropriate use of antimicrobial agents and contributed to elevated multidrug resistance. The aim of this study was to analyze the consumption of antibacterial agents at a hospital complex from 2018 to 2021. Drug utilization study using antibacterial agents consumption data. The groups of antibacterial agents most consumed in the hospital complex were carbapenems, penicillins + beta-lactamase inhibitors, beta-lactamase-resistant penicillins, glycopeptides, and fluoroquinolones. The drugs with a compound annual growth rate that increased by more than 20% from 2018 to 2021 were amikacin (50.12%), benzylpenicillin (24.33%), oral clarithromycin (51.06%), daptomycin (34.38%), polymyxin B (20.85%), and tigecycline (41.49%). According to the AWaRE classification, the antibacterial agents from the Watch group subjected to AWaRE exhibited increased consumption in all years of the study. On the other hand, there was a reduction in the access category. In turn, the consumption of antibacterial agents in the reserve category also increased. The pattern of antimicrobial consumption in the hospital complex showed increased consumption in medical clinics and intensive care units, with a predominance of carbapenems, penicillins + beta-lactamase inhibitors, beta-lactamase-resistant penicillins, glycopeptides, fluoroquinolones, and polymyxin B, reflecting the care profile and influence of the COVID-19 pandemic.

ABSTRACT Aging and face sagging have many causes, and various techniques are used for treatment, including noninvasive procedures, such as focused ultrasound, which uses the principle of collagen regeneration by coagulative necrosis of the dermis layers using radiofrequency, but this procedure has complications. We reported a case of a 54-year-old female patient who complained of poor visual acuity in her right eye three days after a focused ultrasound facial aesthetic procedure, with the best visual acuity of 20/60. Biomicroscopy of the right eye revealed an acute cataract with three points of fibrosis extending from the posterior to the anterior capsule. The patient underwent phacoemulsification surgery with visual rehabilitation and improved vision of 20/20. We hypothesized that the occurrence of acute cataract was related to the inappropriate use of focused ultrasound. causes treatment procedures radiofrequency complications 54yearold yearold 54 year old 2060 20 60 20/60 capsule 2020 20/20 5 206 2 6 20/6 202 20/2 20/

Resumen Introducción. Existe una gran preocupación humana por la resistencia a los antibióticos debido a su uso inadecuado como promotores del crecimiento en la cría de animales. Objetivo. Evaluar el efecto de altos niveles de zinc como sustituto del antibiótico en lechones destetados. Material y métodos. El estudio se realizó de junio a agosto de 2022 en la provincia de Chiriquí, Panamá. El periodo experimental estuvo compuesto por tres fases con 14 días por fase. Los cerdos destetados (n= 54) fueron asignados a uno de tres tratamientos con seis repeticiones por tratamiento y tres cerdos por repetición. Los tratamientos fueron: 1) dieta control, formulada para suplir los requerimientos nutricionales para cerdos destetados; 2) similar al tratamiento 1, más 200 mg de amoxicilina/kg de alimento y 40 mg de florfenicol/kg de alimento durante la fase 1 (P1) y fase 2 (P2), respectivamente; y 3) similar al tratamiento 1, más 2000 ppm y 1600 ppm de zinc durante P1 y P2, respectivamente. En la fase 3 (P3), todos los cerdos fueron alimentados con una dieta común. Resultados. La suplementación con zinc mejoró la ganancia de peso en todas las fases. Los cerdos alimentados con zinc tuvieron mejor relación F:G en P2 en comparación a los cerdos suplementados con antibiótico (p < 0.05). Se encontró una mayor concentración de hemoglobina y porcentaje de monocitos en cerdos alimentados con zinc que en los otros tratamientos (p < 0.05). Los cerdos alimentados con antibiótico o la dieta control tuvieron un menor porcentaje de materia seca fecal en comparación a los suplementados con zinc (p < 0.05). Conclusión. La suplementación de altos niveles de zinc ejerció mejoras, en comparación al antibiótico, en cuanto a la concentración de hemoglobina, incidencia de diarrea y ganancia de peso en cerdos durante los 42 días posteriores al destete.

Abstract Introduction. There is a great human concern about antibiotics resistance due to their inappropriate use as growth promoters in animal husbandry. Objective. To evaluate the effect of a high level of zinc as a substitute to antibiotics in nursery pigs. Material and methods. The study was carried out from June to August 2022 in the province of Chiriqui, Panama. The experimental period was composed of three phases with 14 days per phase. The nursery pigs (n= 54) were distributed to one of three treatments with six replicates per treatment and three pigs per replicate. The treatments were: 1) control diet, which was formulated to meet the nutritional requirements for nursery pigs; 2) similar to treatment 1, plus 200 mg of amoxicillin/kg of feed and 40 mg of florfenicol/kg of feed during phase 1 (P1) and phase 2 (P2), respectively; and 3) similar to treatment 1, plus 2000 ppm and 1600 ppm of zinc during P1 and P2, respectively. In phase 3 (P3), all pigs were fed a common diet. Results. The supplementation of zinc improved the average daily gain in all phases. Pigs fed zinc diet had better F:G ratio in P2 compared to pigs fed antibiotic diet (p < 0.05). A higher concentration of hemoglobin and percentage of monocytes was found in pigs fed with higher level of zinc than the other treatments (p < 0.05). Furthermore, Pigs fed the antibiotic, or the control diet had a lower percentage of fecal dry matter compared to those supplemented with zinc. (p < 0.05). Conclusion. The supplementation of high levels of zinc exerted improvements, in comparison to the antibiotic, in terms of hemoglobin concentration, incidence of diarrhea and weight gain in pigs during 42 days after weaning.

Resumen: El uso continuo e inadecuado de agentes antimicrobianos, tradicionalmente utilizados en odontología, ha provocado el surgimiento de cepas bacterianas multirresistentes (MDR, por sus siglas en inglés), así como la mutación de microrganismos. Esta problemática ha propiciado el desarrollo de varias nanopartículas para combatir patógenos resistentes; las nanopartículas de dióxido de titanio (TiO2) han sido agentes antimicrobianos atractivos debido a su estabilidad química, no toxicidad y precursores económicos. Por lo tanto, las nanodispersiones basadas en TiO2 se exploraron preparándolas con agentes antimicrobianos bien conocidos, como el ácido hipocloroso (HOCl), para mejorar el efecto antimicrobiano. En este estudio, se sintetizaron y caracterizaron nanodispersiones de TiO2 NPs-HOCl basadas en sol-gel. El efecto antimicrobiano se evaluó mediante un ensayo de microdilución utilizando cepas de S. mutans, S. aureus, E. faecalis y C. albicans mediante la incubación de diferentes concentraciones de las nanodispersiones. Para evaluar los efectos citotóxicos, se inocularon células madre de la papila apical (SCAP) y se evaluaron mediante el ensayo MTT. La nanodispersión exhibió un efecto antimicrobiano mejorado, casi sin citotoxicidad. La nanodispersión basada en HOCl exhibió un mayor efecto antimicrobiano y alta estabilidad, por lo cual se puede utilizar como un agente antimicrobiano prometedor para el tratamiento de diversos patógenos dentales.

Abstract: The continuous and inappropriate use of antimicrobial agents, traditionally used in dentistry, has caused the emergence of multidrug-resistant (MDR) bacterial strains, as well as the mutation of microorganisms. This problem has led to the development of several nanoparticles to combat resistant pathogens. Titanium dioxide (TiO2) nanoparticles have been attractive antimicrobial agents because of their chemical stability, non-toxicity, and inexpensive precursors. Therefore, TiO2-based nanodispersions were explored by preparing them with well-known antimicrobial agents, such as hypochlorous acid (HOCl), to enhance the antimicrobial effect. In this study, sol-gel-based TiO2 NPs-HOCl nanodispersions were synthesized and characterized. The antimicrobial effect was assessed by a microdilution assay using S. mutans, S. aureus, E. faecalis, and C. albicans strains by incubating different concentrations of the nanodispersions. To evaluate the cytotoxic effects, stem cells from the apical papilla (SCAPs) were inoculated and evaluated using the MTT assay. The nanodispersion exhibited an enhanced antimicrobial effect, with almost no cytotoxicity. The HOCl-based nanodispersion exhibited a greater antimicrobial effect and high stability. Thus, it can be used as a promising antimicrobial agent for the treatment of various dental pathogens.

Abstract This article examines the condolence discourse of users responding to obituaries posted by local Portuguese funeral parlours on Facebook. Aiming to explore mourning discourse and identify online community dynamics that interact with the physical community surrounding the funeral parlour, we adopted a methodology combining principles of critical discourse analysis and ethnography. The findings reveal several notable aspects: the spaces were marked by informality, evident in the prevalence of misspellings and grammatical errors, the use of pictographic elements (e.g., emojis), and the recurrence of users posting identical comments across posts regardless of the deceased. These spaces also prompted discursive contrasts, ranging from seemingly inappropriate interactions to heartfelt comments sharing personal experiences of grief. Furthermore, they served as venues for remembering, characterising, and imagining the deceased, often through narratives of shared experiences. This discursive diversity is argued to be facilitated by Facebook’s integration into everyday life and its mediated nature. Coupled with an apparent lack of emotional literacy in the digital context, this appears to relieve certain users of responsibility in the discourse produced.

Resumo Este artigo debruça-se sobre o discurso de condolências por parte de utilizadores em obituários publicados por funerárias locais portuguesas no Facebook. Com o objetivo de compreender o discurso de luto e identificar dinâmicas comunitárias online, que dialogam com a comunidade física em que a funerária local se insere, optou-se por uma metodologia que alia princípios da análise crítica do discurso e da etnografia. Desta análise resultaram diversas considerações: revelaram-se espaços de elevada informalidade, visível ao nível da linguagem através da disseminação de erros gramaticais, pela utilização de elementos pictográficos (e.g., emojis), ou pela recorrência de utilizadores que produzem idênticos comentários nas publicações, independentemente de quem morre; motivaram contrastes discursivos, desde interações que poderão ser consideradas despropositadas até comentários que partilham experiências de luto; são espaços com potencial para lembrar, caracterizar e imaginar os mortos, através de relatos de histórias que o utilizador experienciou com a pessoa. É também argumentado que esta imensa diversidade é incentivada pela eficácia do Facebook em se integrar no quotidiano das pessoas e pelo seu caráter mediado que, incentivado pelo que parece ser uma carência de literacia emocional em contexto digital, parece desresponsabilizar certos utilizadores no discurso produzido.

RESUMO Objetivou-se analisar os fatores determinantes sociais da saúde em Angola. Trata-se de uma pesquisa documental, exploratória e quantitativa, realizada com dados do Inquérito de Indicadores Múltiplos e de Saúde 2015-2016 de Angola. Foram analisadas as variáveis: acesso a fontes de água para beber; instalações sanitárias apropriadas; acesso à eletricidade; nível educacional; acesso a empregos; taxa de mortalidade infantil; consultas pré-natais; e cobertura vacinal. Observou-se que 45,2% dos agregados familiares não têm acesso a fontes de água apropriada para beber; 52,9% utiliza instalações sanitárias não apropriadas, principalmente nas áreas rurais; 31% dos homens de 15 a 49 anos estavam desempregados; 42% dos agregados familiares possuíam acesso à eletricidade; 22% das mulheres e 8% dos homens de 15 a 49 anos nunca frequentaram a escola; a estimativa da taxa de mortalidade infantil foi de 44 mortes para cada 1000 nascidos-vivos; 44,1% das gestantes com menor nível socioeconômico não realizaram nenhuma consulta pré-natal; 18,3% das crianças de 12 a 23 meses e 21% de 24 a 35 meses não receberam nenhuma vacina. Conclui-se que existem grandes lacunas no acesso a determinantes sociais da saúde, evidenciando a necessidade de esforços governamentais em parceria com organismos internacionais para melhorar as condições de saúde da população.

ABSTRACT The objective was to analyze the social determinants of health in Angola. This is a documentary, exploratory and quantitative research, carried out with data from the 2015-2016 Multiple Indicators and Health Survey in Angola. The analyzed variables were: access to drinking water sources; appropriate sanitary facilities; access to electricity; educational level; access to jobs; child mortality rate; prenatal consultations; and vaccination coverage. It was observed that 45.2% of households do not have access to adequate water sources for drinking; 52.9% use inappropriate sanitation facilities, mainly in rural areas; 31% of men aged 15 to 49 were unemployed; 42% of households had access to electricity; 22% of women and 8% of men aged 15 to 49 have never attended school; the estimated infant mortality rate was 44 deaths for every 1000 live births; 44.1% of pregnant women with lower socioeconomic status did not undergo any prenatal consultation; 18.3% of children aged 12 to 23 months and 21% aged 24 to 35 months did not receive any vaccine. It is concluded that there are large gaps in access to social determinants of health, highlighting the need for government efforts in partnership with international organizations to improve the population’s health conditions.

ABSTRACT The objective was to analyze the social determinants of health in Angola. This is a documentary, exploratory and quantitative research, carried out with data from the 2015-2016 Multiple Indicators and Health Survey in Angola. The analyzed variables were: access to drinking water sources; appropriate sanitary facilities; access to electricity; educational level; access to jobs; child mortality rate; prenatal consultations; and vaccination coverage. It was observed that 45.2% of households do not have access to adequate water sources for drinking; 52.9% use inappropriate sanitation facilities, mainly in rural areas; 31% of men aged 15 to 49 were unemployed; 42% of households had access to electricity; 22% of women and 8% of men aged 15 to 49 have never attended school; the estimated infant mortality rate was 44 deaths for every 1000 live births; 44.1% of pregnant women with lower socioeconomic status did not undergo any prenatal consultation; 18.3% of children aged 12 to 23 months and 21% aged 24 to 35 months did not receive any vaccine. It is concluded that there are large gaps in access to social determinants of health, highlighting the need for government efforts in partnership with international organizations to improve the population’s health conditions. Angola documentary research 20152016 2015 2016 2015-201 facilities electricity level jobs consultations coverage 452 45 2 45.2 529 52 9 52.9 areas 31 1 4 unemployed 42 22 8 school 100 births 441 44.1 consultation 183 18 3 18.3 21 vaccine populations population s conditions 2015201 201 2015-20 45. 5 52. 10 44. 18. 201520 20 2015-2 20152 2015-

RESUMO Objetivou-se analisar os fatores determinantes sociais da saúde em Angola. Trata-se de uma pesquisa documental, exploratória e quantitativa, realizada com dados do Inquérito de Indicadores Múltiplos e de Saúde 2015-2016 de Angola. Foram analisadas as variáveis: acesso a fontes de água para beber; instalações sanitárias apropriadas; acesso à eletricidade; nível educacional; acesso a empregos; taxa de mortalidade infantil; consultas pré-natais; e cobertura vacinal. Observou-se que 45,2% dos agregados familiares não têm acesso a fontes de água apropriada para beber; 52,9% utiliza instalações sanitárias não apropriadas, principalmente nas áreas rurais; 31% dos homens de 15 a 49 anos estavam desempregados; 42% dos agregados familiares possuíam acesso à eletricidade; 22% das mulheres e 8% dos homens de 15 a 49 anos nunca frequentaram a escola; a estimativa da taxa de mortalidade infantil foi de 44 mortes para cada 1000 nascidos-vivos; 44,1% das gestantes com menor nível socioeconômico não realizaram nenhuma consulta pré-natal; 18,3% das crianças de 12 a 23 meses e 21% de 24 a 35 meses não receberam nenhuma vacina. Conclui-se que existem grandes lacunas no acesso a determinantes sociais da saúde, evidenciando a necessidade de esforços governamentais em parceria com organismos internacionais para melhorar as condições de saúde da população. Objetivouse Objetivou se Angola Tratase Trata documental quantitativa 20152016 2015 2016 2015-201 variáveis beber apropriadas eletricidade educacional empregos prénatais pré natais pré-natais vacinal Observouse Observou 452 45 2 45,2 529 52 9 52,9 rurais 31 1 4 desempregados 42 22 8 escola 100 nascidosvivos nascidos vivos nascidos-vivos 441 44,1 prénatal natal pré-natal 183 18 3 18,3 21 vacina Concluise Conclui população 2015201 201 2015-20 45, 5 52, 10 44, 18, 201520 20 2015-2 20152 2015-

Antimicrobial resistance (AMR), in which microbes adapt to and resist current therapies, is a well-recognised global problem that threatens to reverse gains made by modern medicine in the last decades. AMR is a complex issue; however, at its core, it is driven by the overuse and inappropriate use of antimicrobials. Socioeconomic factors have been identified as significant contributors to the emergence and exacerbation of AMR, especially in populations facing inadequate access to healthcare, poor sanitation services and high morbidity and mortality rates. Weak healthcare systems and water, sanitation and hygiene have been highlighted as fundamental risk factors for AMR emergence and transmission. Behavioural factors, such as purchasing antibiotics without a prescription from a registered healthcare professional, not completing the prescribed course or overly prolonged courses of antibiotics, using antibiotics to treat viral infections, lack of access to quality antibiotics, and the proliferation of substandard or falsified (SF) drugs, have also been identified as significant contributors to AMR. Low- and middle-income countries have a higher incidence of antibiotics being dispensed without a prescription than higher-income countries.

RESUMEN Introducción: El uso inadecuado de antibióticos contribuye al aumento de la resistencia bacteriana, las cepas resistentes son muy difíciles de tratar con los antibióticos disponibles. Objetivo: Evaluar la efectividad del tratamiento farmacológico empírico con Cefotaxima y Ceftriaxona en servicios clínicos y quirúrgicos del hospital “Dr. Benigno Sánchez” de Quillacollo, durante la gestión 2022. Metodología: Es un estudio observacional de tipo analítico, subtipo casos y controles, longitudinal prospectivo. La población fue pacientes 1395, obteniendo una muestra de 884 pacientes subdividiendo en grupos casos n=741 y controles n=126. Resultados: En el servicio quirúrgico la frecuencia entre varones y mujeres fue de 45 % y 55 % respectivamente; 73 % del total no presentó enfermedades de base, el 90 % del total tuvo una hospitalización de menos de una semana con 95 % de mejoría sin diferencia significativa entre casos y controles. En el servicio de clínico, 60 % fueron mujeres el resto varones, 50 % del total no presentó enfermedades de base, el 78 % del total tuvo una hospitalización de menos de una semana con 85 % de mejoría sin diferencia significativa entre casos y controles. Discusión: Las características sociodemográficas, el presente estudio identificó que en el servicio quirúrgico a la edad media fue 43 años, de estos 45 % fueron varones y 55 % mujeres, en cambio en el servicio clínico, la edad media fue de 55 años, 60 % mujeres el resto varones. El presente estudio identificó que, en el servicio quirúrgico, el 95 % de los casos cuentan con mejoría, sin que exista una relación entre la terapia empleada o no. En el servicio clínico se apreció un 85 % de mejoría sin que exista diferencia entre los grupos. No existe una diferencia significativa entre los grupos, en los servicios medico quirúrgicos, con respecto a la mejoría.

ABSTRACT Introduction: Inappropriate use of antibiotics contributes to the increase in bacterial resistance; resistant strains are very difficult to treat with available antibiotics. Objective: To evaluate the effectiveness of empirical pharmacological treatment with Cefotaxime and Ceftriaxone in clinical and surgical services of the “Dr. Benigno Sánchez” from Quillacollo, during the 2022 administration. Methodology: It is an observational study of analytical type, case-control subtype, prospective longitudinal. The population was 1395 patients, obtaining a sample of 884 patients, subdividing cases n=741 and controls n=126 into groups. Results: In the surgical service, the frequency among men and women was 45 % and 55 % respectively; 73 % of the total did not present underlying diseases, 90 % of the total had a hospitalization of less than one week with 95 % improvement without significant difference between cases and controls. In the clinical service, 60 % were women, the rest men, 50 % of the total did not present underlying diseases, 78 % of the total had a hospitalization of less than a week with 85 % improvement without significant difference between cases and controls. Discussion: The sociodemographic characteristics, the present study identified that in the surgical service the average age was 43 years, of these 45 % were men and 55 % women, however in the clinical service, the average age was 55 years, 60 % women the rest men. The present study identified that, in the surgical service, 95 % of the cases have improvement, without there being a relationship between the therapy used or not. In the clinical service, an 85 % improvement was seen with no difference between the groups. There is no significant difference between the groups, in medical surgical services, with respect to improvement.

Resumen Problema: tradicionalmente se ha excluido de la esfera de consideración moral tanto al ambiente como a otros animales, aun cuando una relación positiva con ellos reporta beneficios para la salud de unas y otras criaturas y promueve el desarrollo de empatía y la emisión de conductas prosociales (Ngai, Yu, Chau, Lee y Wong, 2021). De hecho, en las últimas décadas se han observado casos de zoonosis, uso inadecuado de recursos, deterioro del ambiente y un aumento de casos registrados de abuso animal. El abuso animal, fenómeno complejo y multideterminado, frecuentemente funciona como precursor o indicador de otras conductas calificadas como “antisociales”, violentas y no violentas. Respecto del rol que juega la empatía en la emisión o inhibición de conductas agresivas y de cuán generalizable es la empatía interespecie, existe evidencia contradictoria y se resaltan aquí tres fenómenos de interés: erosión empática, desensibilización progresiva a la violencia y fatiga por compasión. Objetivo: determinar si los niveles de empatía, la disposición a comportarse de manera abusiva contra otros animales y la conducta efectiva de abuso animal se relacionan con el contexto de formación preprofesional, el género autopercibido y la tenencia actual y/o previa de animales de compañía en estudiantes universitarios que cursan el tramo final de la Licenciatura en Psicología. Metodología: diseño ex post facto retrospectivo de grupo único (N = 241). Se aplicó un cuestionario autoadministrado que incluyó el Interpersonal Reactivity Index, la Animal Empathy Scale, la Animal Abuse Proclivity Scale y la cantidad y frecuencia de conductas efectivas de abuso animal. Contribución: se evidencia sobre el aporte del género autopercibido a la relación entre diversas medidas de empatía y el abuso hacia otros animales y se refuerza la tesis de la no generalizabilidad de la empatía interespecie.

Abstract Problem: Traditionally, both the environment and other animals have been excluded from the sphere of moral consideration, even though humans’ positive relationship with them brings benefits for the health of both creatures and promotes the development of empathy and the display of prosocial behaviors (Ngai, Yu, Chau, Lee & Wong, 2021). In fact, in recent decades there have been cases of zoonoses, inappropriate use of resources, deterioration of the environment and an increase in recorded cases of animal abuse. Animal abuse, a complex and multi-determined phenomenon, frequently works as a precursor or indicator of other behaviors classified as “antisocial”, violent and non-violent. There is conflicting evidence regarding the role that empathy plays in the emission or inhibition of aggressive behaviors and how generalizable interspecies empathy is. In this respect, three phenomena of interest stand out: empathic erosion, progressive desensitization to violence and compassion fatigue. Objective: To determine whether the levels of empathy, the willingness to behave abusively against other animals, and actual animal abuse behavior are related to the context of pre-professional training, self-perceived gender, and current and/or previous ownership of other companion animals in university students who are in the final stage of their training to obtain their university degree in Psychology. Methodology: Retrospective ex post facto single case design (N=241). A self-administered questionnaire was applied that included the Interpersonal Reactivity Index, the Animal Empathy Scale, the Animal Abuse Proclivity Scale and the quantity and frequency of effective animal abuse behaviors. Contribution: the contribution of self-perceived gender to the relationship between various measures of empathy and abuse towards other animals is evidenced, and the thesis of the non-generalizability of interspecies empathy is reinforced.

Resumen Introducción : Los adultos mayores con enfermedades crónicas avanzadas y necesidad de cuidados paliativos están más expuestos a la polifarmacia y a consumir medicación potencialmente inapropiada, la cual genera un alto riesgo de eventos adversos y alteración de la calidad de vida. El objetivo de este estudio fue describir la frecuencia de consumo de medicación potencialmente inapropiada de adultos mayores con necesidad de cuida dos paliativos que ingresaron a cuidados domiciliarios luego de una hospitalización. Métodos : Estudio de corte transversal observacional de registros de dispensación e historias clínicas electró nicas, de adultos mayores en un sistema de cuidados domiciliarios y con necesidades de cuidados paliativos según el rastreo con la herramienta NECPAL, los índices PROFUND y/o PALIAR. Se analizó el consumo de fárma cos durante los 180 días posteriores al ingreso a cuidados domiciliarios. Se clasificaron los fármacos como poten cialmente inapropiados según criterios de LESS-CHRON. Resultados : Se incluyeron 176 pacientes, edad prome dio 87.4 años, 67% mujeres; 78% eran pluripatológicos y 22% presentaban una enfermedad única crónica progre siva. La mortalidad a los 6 meses fue 73%. La mediana de consumo de fármacos por paciente fue 9.1 (RIC = 4-9.7). El 87% consumía medicación potencialmente inapropia da, principalmente antihipertensivos, benzodiacepinas y antipsicóticos. Conclusión : Este estudio observó que los adultos ma yores, con necesidad de cuidados paliativos en cuidados domiciliarios, tienen un alto consumo de medicación potencialmente inapropiada. Esto refuerza la necesidad de implementar intervenciones efectivas centradas en el paciente, para prevenir la prescripción inadecuada y estimular la de-prescripción.

Abstract Introduction : Older adults with advanced chronic diseases and palliative care needs are more exposed to polypharmacy and use of potentially inappropriate medication, which generates a high risk of adverse events and impaired quality of life. The objective of this study was to describe the frequency of potentially inappropriate medication use among older adults with palliative care needs receiving home care services after hospital discharge. Methods : Observational cross-sectional study of pharmacy dispensing and electronic health records, of older adults in a home care system and with palliative care needs according to the screening with the NECPAL tool or the PROFUND and/or PALIAR indexes. Dispensed medications during 180 days after admission to home care were analyzed. Medications were classified as po tentially inappropriate according to the LESS-CHRON criteria. Results : We included 176 patients, mean age 87.4 years, 67% were women; 73% were pluripathologic pa tients and 22% had one chronic progressive disease. Mortality at 6 months was 73%. Median frequency of dispensed medications per patient was 9.1 (IQR = 4-9.7). The frequency of potentially inappropriate medication dispensation among patients was 87%, mainly antihy pertensives, benzodiazepines and antipsychotics. Conclusion : This study observed that dispensation of potentially inappropriate medication among older adults with palliative care needs and home care services is very high. This emphasizes the need for effective patient-centered interventions to prevent inadequate prescription and stimulate de-prescription.

Abstract: This study aims to identify and analyze the main research streams on digital safety and online privacy related to higher education students. Students are at risk of cybercrime, including online harassment, identity theft, and exposure to inappropriate content. A systematic literature review is conducted on digital security, cybersecurity, Internet security, online safety, and use of digital technologies. The results show that publications on digital security for higher education students have increased consistently during the last two decades. The main research streams are: digital risk and student perspectives, digital children, digital teenagers, online harassment, and digital behavior. In conclusion, this study provides a wide assessment on digital security for university students and highlights the importance of future research on improving awareness and safety on digital environments for teenagers.

Resumen: Este estudio tiene como objetivo identificar y analizar las principales corrientes de investigación en seguridad digital y privacidad en línea para estudiantes de educación superior. Los estudiantes están en riesgo de ser víctimas de ciberdelitos, como el acoso en línea, el robo de identidad y la exposición a contenido inapropiado. Se realiza una revisión sistemática de la literatura sobre seguridad digital, ciberseguridad, seguridad en Internet y uso de tecnologías digitales. Los resultados muestran que la producción científica sobre seguridad digital en estudiantes de educación superior ha experimentado un crecimiento sostenido durante las últimas dos décadas. Las corrientes de investigación más destacadas son: riesgo digital y perspectivas estudiantiles, digital children, jóvenes digitales, ciberacoso y comportamiento digital. En conclusión, se proporciona una visión amplia sobre la seguridad digital en estudiantes universitarios y se destaca la importancia de futuras investigaciones para mejorar la conciencia y protección de los jóvenes en el entorno digital.

BACKGROUND. Various mechanisms may contribute to and direct the progression of antibiotic resistance. A prominent driver associated with antibiotic resistance is inappropriate use or consumption. The sudden emergence of coronavirus disease 2019 (COVID-19 ) changed the conventional practices related to antibiotic utilisation through repurposing the use of antibiotics. Apart from the implementation of antibiotic stewardship programmes, the pressure COVID-19 placed on healthcare systems resulted in poor prescribing and medication review practices, potentially exacerbating antibiotic resistance. Furthermore, the public health system has issues that make it difficult to routinely monitor, quantify antibiotic consumption, and offer evaluation, feedback and intervention, particularly in low- and middle-income countries such as South Africa (SA). Therefore, this study aimed to determine antibiotic utilisation before and during the COVID-19 pandemic in a Gauteng provincial tertiary hospital (GPTH) in SA. OBJECTIVE. To determine, examine, and compare antibiotic consumption among intensive care unit (ICU) patients admitted to a GPTH during the pre-COVID-19 period and during the COVID-19 pandemic, in addition to determining the prevalence of the World Health Organisation (WHO) 'watch' category antibiotics before and following the emergence of COVID-19. METHODS. A retrospective cross-sectional data analysis was undertaken of 335 medical files of ICU patients hospitalised in a GPTH between January 2017 and December 2021. Descriptive statistics were used to examine patient characteristics and antibiotic prescribing variables (antibiotic selection, dosage, route of administration, frequency, duration of course and indication for which antibiotic was prescribed). RESULTS. The study found that the most frequently prescribed antibiotics were amoxicillin in combination with clavulanate (pre-pandemic 31.99%; amid-COVID-19 38.43%), followed by ceftriaxone (pre-pandemic 15.44%; amid-COVID-19 14.55%), piperacillin in combination with tazobactam (pre-pandemic 11.40%; amid-COVID-19 8.58%) and azithromycin (pre-pandemic 7.725%; amid-COVID-19 19.78%). CONCLUSION. The macrolide and penicillin (in combination with a beta-lactamase inhibitor) classes demonstrated an increase in consumption from the pre-pandemic period moving into the COVID-19 pandemic. This highlights the need for improved antibiotic stewardship programmes and policies to combat inappropriate and unnecessary antibiotic usage.

Compositing or regularization of drillhole data is common practice in mineral resource estimation and is deemed a necessary step in producing unbiased estimates of mineral resources and reserves. Commonly, data are collected over irregular distances due to the varying relative thicknesses of lithologies drilled or sampling/assaying strategies. This necessitates data transformation to regular lengths of equal size to ensure that all data have the same sample support. However, there have been few detailed publications on the effect of this process on the composited data that are subsequently taken forward for the estimation process. In this paper, three currently available compositing methods are reviewed and the effects of inappropriate compositing methodologies presented. It is shown through a case study that compositing samples to different lengths leads to changes in the average and variance of the grades in the drillcores in the dataset, which will impact the final estimated value. These differences are exacerbated by breaks or gaps in data where, for a variety of reasons, there has been no data collection or data have been lost. The importance of appropriately treating blank and zero data is also presented. Globally, these differences might be minimal, but locally may be substantial, affecting the efficiency of the estimation and subsequent use of the results in, for example, mine planning and reconciliation. Further detailed investigation of compositing practices is required if the full implications of compositing are to be understood and any induced bias effectively defined.