Abstract The critical importance of wetland ecosystems is highlighted, as they provide essential services such as regulating the hydrological cycle, flood control, and filtering pollutants. Globally, 64 % of wetlands have been lost since 1970, with Asia being the most affected region. Agricultural expansion, urban development, and aquaculture are some of the main drivers of the degradation of these ecosystems, particularly mangroves, which play a key role in climate change mitigation. In Costa Rica, wetlands under inventory represent 6.01 % of the national territory, and although the country has made progress in their protection, with 49 % of wetlands falling under some category of protected wild area, challenges remain, such as agricultural expansion, livestock farming, and sedimentation. At the international level, the Ramsar Convention has been key to wetland conservation efforts, with over 2.57 million km2 protected. However, additional efforts are needed to mitigate the threats to these ecosystems, especially in the context of climate change.

Resumen Se resalta la importancia crítica de los ecosistemas de humedales, que proporcionan servicios esenciales, como la regulación del ciclo hidrológico, el control de inundaciones y la filtración de contaminantes. En el nivel global, se ha perdido un 64 % de los humedales desde 1970, con Asia siendo la región más afectada. La expansión agrícola, el desarrollo urbano y la acuicultura son algunas de las principales causas de la degradación de estos ecosistemas, especialmente de los manglares, que cumplen una función clave en la mitigación del cambio climático. En Costa Rica, los humedales bajo inventario representan el 6.01 % del territorio nacional, y aunque el país ha avanzado en su protección, con el 49 % de los humedales bajo alguna categoría de área silvestre protegida, persisten desafíos, como la expansión agrícola, la ganadería y la sedimentación. En el plano mundial, la Convención Ramsar ha sido clave en los esfuerzos de conservación de humedales, con más de 2.57 millones km2 protegidos. Sin embargo, se necesitan esfuerzos adicionales para mitigar las amenazas a estos ecosistemas, especialmente en el contexto del cambio climático.

Abstract The article addresses some effects of the transformation of industrial spaces in Barcelona since the second half of the 1980s. It describes the phases of industrial heritage management in the city since the beginning of democracy and analyzes citizen resistances and actions arising in the context of the contradictions between collective identity, local development, and the global projection of the city that the transformation of industrial space generates. To illustrate these processes, two cases of factory complexes located in two of the city’s main industrial complexes are studied: Can Ricart (District X, Sant Martí) and Can Batlló (District III, Sants-Montjuïc). 1980s s identity development generates processes citys studied District X Martí III SantsMontjuïc. SantsMontjuïc Sants Montjuïc . Sants-Montjuïc) Sants-Montjuïc

Resumen El artículo desgrana algunos de los efectos de la transformación de los espacios industriales en Barcelona desde la segunda mitad de los años ochenta del siglo XX. Describe las fases de la gestión del patrimonio industrial en la ciudad condal desde los inicios de la democracia y analiza las resistencias y acciones ciudadanas que se originan en el contexto de las contradicciones entre la identidad colectiva, el desarrollo local y la proyección global de ciudad que la transformación del espacio industrial genera. Para ilustrar estos procesos se estudian dos casos de complejos fabriles situados en dos de los principales conjuntos industriales de la ciudad: Can Ricart (Distrito X, Sant Martí) y Can Batlló (Distrito III, Sants-Montjuïc). XX colectiva genera Distrito X Martí III SantsMontjuïc. SantsMontjuïc Sants Montjuïc . Sants-Montjuïc) Sants-Montjuïc

Resumo Hub Criativo do Beato é uma infraestrutura voltada à inovação digital da cidade de Lisboa, Portugal, que vem sendo constituída, desde 2016, por um processo que chamo de refuncionalização contínua e flexível de um antigo complexo industrial militar. Também a compreendo como âncora de reabilitação urbana e como dispositivo de representação para uma Lisboa que compete internacionalmente por atração de capitais em contexto de ascensão global da economia digital. Multiplicidade de ideias, experimentações, aberturas a mudanças e adaptações dão o tom dos projetos lá realizados. O artigo busca compreender criticamente os enlaces possíveis entre produção do urbano e economia digital. Trata-se de um estudo de caso derivado de pesquisa qualitativa de caráter explicativo-interpretativo e baseada no modelo grounded theory. Portugal constituída 2016 militar ideias experimentações realizados Tratase Trata se explicativointerpretativo explicativo interpretativo theory 201 20 2

Abstract Hub Criativo do Beato is an infrastructure targeted at digital innovation in the city of Lisbon, Portugal, that has been constituted, since 2016, through a process that I call continuous and flexible repurposing of an old military-industrial complex. I also understand it as an anchor for urban rehabilitation and as a representation apparatus for a city that competes internationally to attract capital in the context of the global rise of the digital economy. A multiplicity of ideas, experiments, and openness to change and adaptations guide its projects. The article seeks to critically understand the connections between urban production and the digital economy. This case study derives from qualitative research of an explanatory--interpretive nature based on grounded theory. Lisbon Portugal constituted 2016 militaryindustrial military industrial complex economy ideas experiments projects explanatoryinterpretive explanatory interpretive theory 201 20 2

Resumo O artigo insere-se em pesquisa abrangente sobre o legado e a potência dos remanescentes industriais suburbanos, refletindo sobre contradições e oportunidades para uma transformação urbana. Enfatiza efeitos socioespaciais da industrialização e desindustrialização latino-americanos, focando nos subúrbios ferroviários da zona norte do Rio de Janeiro, priorizados nas políticas desenvolvimentistas brasileiras. Autores da geografia crítica e da antropologia etnográfica que destacam interações locais e globais, ininterruptas dinâmicas urbanas e multiplicidade de lógicas, práticas e formas territoriais, são referências para a pesquisa. Avalia-se que, mesmo acirradas as contradições e os conflitos decorrentes de processos históricos, hoje há capital material e simbólico potencial para beneficiar populações locais, se considerada a pluralidade nas relações sociais e acionadas forças presentes nos principais agentes atuantes no espaço suburbano. inserese insere suburbanos urbana latinoamericanos, latinoamericanos latino americanos, americanos latino-americanos Janeiro brasileiras globais lógicas territoriais Avaliase Avalia históricos suburbano

Abstract This article integrates a comprehensive study of the legacy and potential of suburban industrial remnants and reflects on contradictions and opportunities for urban transformation. It emphasizes the socio-spatial effects of industrialization and deindustrialization in Latin America while focusing on the railway suburbs of the North Zone of Rio de Janeiro, prioritized in Brazilian developmental policies. Authors in the fields of critical geography and ethnographic anthropology who highlight local and global interactions, uninterrupted urban dynamics, and multiple logics, practices, and territorial forms are references for the research. Despite increased contradictions and conflicts deriving from historical processes, today there is a potential material and symbolic capital to benefit local populations if plurality in social relations is considered and forces present in the main agents who act in the suburban space are activated. transformation sociospatial socio spatial Janeiro policies interactions dynamics logics practices research processes activated

Resumo Este artigo tem como objetivo compreender a recepção do fascismo entre os intelectuais ligados à direita católica nos anos 1930, com ênfase nos debates travados na revista A Ordem. Procuramos mostrar como – em uma análise contextual do pensamento político que parte da necessidade de entender como as ideias circulam e são apropriadas e contra que problemas históricos elas são mobilizadas – as fronteiras ideacionais entre conservadorismo, reacionarismo, tradicionalismo católico e fascismo são muito tênues. A ênfase aqui, portanto, é no repertório semântico mobilizado pelos atores. Ao fim, o artigo pretende compreender as afinidades entre essas linguagens políticas para produzir uma teorização do pensamento reacionário de modo mais amplo, que não leve em conta apenas as suas manifestações paradigmáticas do Norte, mas que seja capaz de pensar a crítica das direitas à democracia a partir da experiência de recepção e circulação dessas linguagens políticas no Sul global. 1930 Ordem conservadorismo reacionarismo tênues aqui portanto atores fim amplo Norte global 193 19 1

Résumé Cet article vise à comprendre la réception du fascisme par les intellectuels liés à la droite catholique dans les années 1930, en mettant l’accent sur les débats menés dans la revue « A Ordem ». Nous cherchons à montrer comment - dans une analyse contextuelle de la pensée politique qui part de la nécessité de comprendre comment les idées circulent et sont appropriées et contre quels problèmes historiques elles sont mobilisées - les frontières idéationnelles entre conservatisme, réactionnisme, traditionalisme catholique et fascisme sont très ténues. L’accent ici est donc mis sur le répertoire sémantique mobilisé par les acteurs. En fin de compte, l’article vise à comprendre les affinités entre ces langages politiques pour produire une théorisation de la pensée réactionnaire de manière plus large, qui ne tienne pas seulement compte de ses manifestations paradigmatiques du Nord, mais qui soit capable de penser la critique des droites à la démocratie à partir de l’expérience de réception et de circulation de ces langages politiques dans le Sud global. 1930 laccent l accent » conservatisme réactionnisme ténues Laccent L acteurs larticle large Nord lexpérience expérience global 193 19 1

Abstract The purpose of this article is to understand the reception of fascism among intellectuals linked to the Catholic right in the 1930s, with emphasis on the debates held in the magazine A Ordem. We intend to show how – in a contextual analysis of political thought that starts from the need to understand how ideas circulate and are appropriated and against which historical problems they are mobilized – the ideational boundaries between conservatism, reactionaryism, Catholic traditionalism and fascism are very subtle. The emphasis here, therefore, is on the semantic repertoire that the actors mobilize. In the end, the article intends to understand the affinities between these political languages to produce a theorization of reactionary thought in a broader way, which does not only take into account its paradigmatic manifestations of the North, but which is capable of thinking about the right-wing critique of democracy from the experience of reception and circulation of these political languages in the global South. 1930s s Ordem conservatism reactionaryism subtle here therefore mobilize end way North rightwing wing South

Resumen Este artículo tiene como objetivo comprender la recepción del fascismo entre los intelectuales vinculados a la derecha católica en la década de 1930, con énfasis en los debates realizados en la revista A Ordem. Buscamos mostrar cómo – en un análisis contextual del pensamiento político que parte de la necesidad de comprender cómo circulan y se apropian las ideas y contra qué problemas históricos se movilizan – las fronteras ideacionales entre conservadurismo, pensamento reaccionario, tradicionalismo católico y fascismo son muy tenues. El énfasis aquí, por lo tanto, está en el repertorio semántico movilizado por los actores. Al final, el artículo se propone comprender las afinidades entre estos lenguajes políticos para producir una teorización del pensamiento reaccionario de manera más amplia, que no solo tenga en cuenta sus manifestaciones paradigmáticas del Norte, sino que sea capaz de pensar la crítica derechista de la democracia desde la experiencia de recepción y circulación de estos lenguajes políticos en el Sur global. 1930 Ordem conservadurismo tenues aquí tanto actores final amplia Norte global 193 19 1

Faced with the global challenge of water treatment, the investigation of the removal of endocrine disruptor compounds (EDCs) in aquatic environments is essential to protect human and animals health. In this study, a novel nanocomposite was prepared from biochar from agricultural waste (corn cob) and maghemite (γ-Fe2O3) nanoparticles, named PCCN, to remove four EDCs (triclosan, 17α-ethinylestradiol, methylparaben, and bisphenol A) from aqueous solutions by adsorption. For the characterization of PCCN, the advanced techniques Fourier transform infrared spectroscopy (FTIR), Brunauer-Emmett-Teller analysis (BET), pH of point of zero charge (pHpzc), scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD) and thermogravimetry (TGA) were employed. Competitive adsorption equilibrium studies of EDCs were performed with PCCN and compared to unmodified biochar (PCC). The pH effect showed that optimal adsorption of EDCs was at pH 8.0 for PCC and pH 6.0 for PCCN. The salt concentration did not influence EDCs in the adsorption. In the adsorption isotherm, the results fitted the Freundlich isotherm model (R2 > 0.903) and the adsorption kinetics were well described by the pseudo-second-order model (R2 > 0.985). Furthermore, the desorption studies indicated that the PCCN can be reused. Thus, the investigation suggests PCCN has promising potential in the removal of EDCs from wastewater. treatment (EDCs health study corn cob γFe2O3 γFeO γ Fe2O3 Fe O (γ-Fe2O3 nanoparticles triclosan, triclosan (triclosan 17αethinylestradiol, 17αethinylestradiol αethinylestradiol 17α ethinylestradiol, ethinylestradiol α 17α-ethinylestradiol methylparaben A FTIR, FTIR , (FTIR) BrunauerEmmettTeller Brunauer Emmett Teller BET, BET (BET) pHpzc, pHpzc (pHpzc) SEM, SEM (SEM) TEM, TEM (TEM) Xray X ray XRD (XRD TGA (TGA employed PCC. . (PCC) 80 8 0 8. 60 6 6. R2 R (R 0.903 0903 903 pseudosecondorder pseudo second order 0.985. 0985 0.985 985 0.985) Furthermore reused Thus wastewater γFe γFe2O FeO Fe2O (γ-Fe2O (FTIR (BET (pHpzc (SEM (TEM (PCC 0.90 090 90 098 0.98 98 0.9 09 9 0.

Integrationist methodologies to climate justice aim to formulate a conception of justice that encompasses principles of global and intergenerational justice, arguing we should treat climate issues in the light of this general theory. In this article, we contend that there are compelling reasons to pursue a minimal conception of justice, and, within this context, Rawls' late conception of public reason is particularly relevant. We propose that a minimal conception of justice for an integrationist approach need not be bound by specific overarching global principles to govern the global international society. The mechanism of public reason can facilitate agreement between climate issues and other related issues by allowing countries to appeal to reasons that reflect the shared and implicit values of constitutional democracies found in international institutions. Although this approach may introduce more ambiguity, it also results in a less idealized scenario, which in turn can contribute to integrating climate and social justice at a minimal level. In summary, we advocate for a two-fold approach, involving both a far-reaching maximum conception of justice and a flexible minimal conception that prioritizes international deliberation and shared values as the means to address diverse dimensions of justice within the global context. theory article context Rawls relevant society institutions ambiguity scenario level summary twofold two fold farreaching far reaching

RESUMO: O vírus da diarreia viral bovina (BVDV) é um vírus que afeta a produção e reprodução com alto impacto econômico global nos sistemas de produção de leite. Nosso objetivo foi investigar a prevalência do BVDV em rebanhos e indivíduos na região de maior produção de leite do Brasil. A frequência do BVDV nos rebanhos foi investigada usando reação em cadeia da polimerase com transcrição reversa quantitativa (RT-qPCR) em tanques de leite em 289 fazendas leiteiras, monitoradas entre agosto de 2020 e janeiro de 2022. Dentre esses rebanhos, 68 sistemas de produção foram selecionados para investigar a prevalência de animais persistentemente infectados (PI) usando dois testes imunoenzimáticos para a detecção do antígeno (Ag-ELISAs), em intervalos de 21 dias, a partir de amostras de tecido auricular. No total, foram realizados 2.902 RT-qPCR e 23.466 Ag-ELISAs. Na investigação dos rebanhos, 23,9% (69/289) das propriedades leiteiras foram consideradas infectadas, apresentando pelo menos um teste qPCR positivo. Na pesquisa de animais Pis, 41,2% (28/68) das fazendas selecionadas tiveram pelo menos um animal positivo no teste Ag-ELISA. A associação entre os testes permitiu classificar as propriedades em quatro categorias: nível 0, negativo para ambos os testes (41,2%, 28/68); nível 1, RT-qPCR positivo e Ag-ELISA negativo (17,6%, 12/68); nível 2, RT-qPCR negativo e Ag-ELISA positivo (13,23%, 9/68); e nível 3, positivo para ambos os testes (27,9%, 19/68). A análise de correspondência múltipla (MCA) sugeriu associação entre positividade para BVDV e grandes propriedades, produção média diária de leite do rebanho, raça e contagem de células somáticas. O confinamento e a intensificação de animais de diferentes categorias e o uso de camas artificiais estão associados à infecção pelo BVDV. O uso de leite residual ou a granel também foi um fator de risco para positividade para BVDV em RT-qPCR e Ag-ELISA. Apesar da utilização de vacinas reprodutivas pela maioria dos produtores, a sua utilização parece estar associada a explorações positivas para BVDV. Este estudo apresenta as frequências epidemiológicas do BVDV nos rebanhos e indivíduos de rebanhos da região dos Campos Gerais Paranaense. A região está entre as principais áreas produtoras de leite do Brasil. Além disso, a associação entre os testes de BVDV e as características da fazenda indica o risco da fazenda para o BVDV e orienta programas de controle específicos. RESUMO (BVDV Brasil RTqPCR RT (RT-qPCR 28 202 2022 6 PI (PI AgELISAs, AgELISAs Ag ELISAs , (Ag-ELISAs) 2 dias auricular total 2902 902 2.90 23466 23 466 23.46 AgELISAs. ELISAs. Ag-ELISAs 239 9 23,9 69/289 69289 69 (69/289 infectadas Pis 412 41 41,2 28/68 2868 (28/68 AgELISA. AgELISA ELISA. ELISA 0 41,2%, (41,2% 28/68) 1 17,6%, 176 17 (17,6% 12/68 1268 12 12/68) 13,23%, 1323 13 (13,23% 9/68 968 9/68) 3 27,9%, 279 27 (27,9% 19/68. 1968 19/68 . 19 19/68) MCA (MCA rebanho somáticas produtores Paranaense disso específicos 20 (Ag-ELISAs 290 90 2.9 2346 46 23.4 23, 69/28 6928 (69/28 4 41, 28/6 286 (28/6 (41,2 17,6% (17,6 12/6 126 13,23% 132 (13,23 9/6 96 27,9% (27,9 196 19/6 29 2. 234 23. 69/2 692 (69/2 28/ (28/ (41, 17,6 (17, 12/ 13,23 (13,2 9/ 27,9 (27, 19/ 69/ (69/ (28 (41 17, (17 13,2 (13, 27, (27 (69 (2 (4 (1 13, (13 (6 (

ABSTRACT: Bovine viral diarrhea virus (BVDV) is a productive and reproductive virus with a high global economic impact on dairy production systems. We investigated the prevalence of BVDV at the herd and individual levels in most dairy-producing regions of Brazil. The frequency of BVDV at the herd level was investigated using quantitative reverse transcription polymerase chain reaction (RT-qPCR) in bulk milk tanks monitored at 289 dairy farms between August 2020 and January 2022. Among these farms, 68 production systems were selected to investigate the prevalence of persistently infected (PI) animals using two antigen-enzyme-linked immunosorbent assays (Ag-ELISAs), at 21-d intervals, from ear-notch samples. In total, 2,902 RT-qPCR and 23,466 Ag-ELISAs were performed. At the herd level, 23.87% (69/289) of dairy farms were considered infected, presenting at least one qPCR test positive. At the individual level, 41.2% (28/68) of the subgroup of selected farms had at least one animal positive in the Ag-ELISA test. Association between tests allowed the classification of farms into the following four categories: level 0, negative for both tests (41.2%, 28/68); level 1, RT-qPCR positive and Ag-ELISA negative (17.6%, 12/68); level 2, RT-qPCR negative and Ag-ELISA positive (13.2%, 9/68); and level 3, positive for both tests (27.9%, 19/68). Multiple correspondence analysis (MCA) suggested a possible association between BVDV positivity and large farms, average daily milk production (herd), breed, and somatic cell counts. The confinement and intensification of animals from different categories, and use of artificial bedding are associated with BVDV infection. Using waste or bulk tank milk to fed calves was also a risk factor for BVDV positivity in RT-qPCR and Ag-ELISA. Despite the use of reproductive vaccines by most producers, their use seems to be associated with BVDV-positive farms. This study presented the epidemiological frequencies of BVDV at the individual and herd levels in the Campos Gerais Paranaense region. The region ranks among the top milk-producing areas in Brazil. Additionally, the association between BVDV tests and farm characteristics indicated the farm risk for BVDV and guides specific control programs. ABSTRACT (BVDV dairyproducing producing Brazil RTqPCR RT (RT-qPCR 28 202 2022 6 PI (PI antigenenzymelinked antigen enzyme linked AgELISAs, AgELISAs Ag ELISAs , (Ag-ELISAs) 21d d 21 intervals earnotch ear notch samples total 2902 2 902 2,90 23466 23 466 23,46 performed 2387 87 23.87 69/289 69289 69 (69/289 412 41 41.2 28/68 2868 (28/68 AgELISA ELISA categories 0 41.2%, (41.2% 28/68) 1 17.6%, 176 17 (17.6% 12/68 1268 12 12/68) 13.2%, 132 13 (13.2% 9/68 968 9 9/68) 3 27.9%, 279 27 (27.9% 19/68. 1968 19/68 . 19 19/68) MCA (MCA herd, (herd) breed counts infection AgELISA. ELISA. producers BVDVpositive milkproducing Additionally programs 20 (Ag-ELISAs 290 90 2,9 2346 46 23,4 238 8 23.8 69/28 6928 (69/28 4 41. 28/6 286 (28/6 (41.2 17.6% (17.6 12/6 126 13.2% (13.2 9/6 96 27.9% (27.9 196 19/6 (herd 29 234 23, 23. 69/2 692 (69/2 28/ (28/ (41. 17.6 (17. 12/ 13.2 (13. 9/ 27.9 (27. 19/ 69/ (69/ (28 (41 17. (17 13. (13 27. (27 (69 (2 (4 (1 (6 (

The coronavirus disease (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has had a profound impact on global health and socio-economic conditions. To date, various vaccines have been administered worldwide in an effort to curb the spread of the virus. Despite vaccination efforts, there have been complications. Existing antiviral drugs have shown limited effectiveness, prompting the use of computational methods to understand the dynamics of the virus and develop suitable treatments. The current study focuses on using biocompatible para-sulfonato-calix[4]arenes to dock against two key proteins of SARS-CoV-2, namely ribonucleic acid (RNA)-dependent RNA polymerase, and helicase. Docking results indicate a strong binding affinity of these compounds to the target proteins, with higher scores compared to commonly used medications. Molecular dynamics (MD) simulation validates the docking results, showing stable protein-ligand complexes over time. The compounds are also screened for absorption, distribution, metabolism, and excretion properties and toxicity, suggesting their potential as lead candidates for inhibiting the virus’s key proteins. However, further in vivo and in vitro studies are recommended to confirm these findings. COVID19 COVID 19 (COVID-19 pandemic SARSCoV2, SARSCoV2 SARSCoV SARS CoV , (SARS-CoV-2) socioeconomic socio economic conditions date efforts complications effectiveness treatments parasulfonatocalix4arenes parasulfonatocalixarenes para sulfonato calix 4 arenes 2, SARS-CoV-2 RNAdependent dependent polymerase helicase medications MD (MD proteinligand protein ligand time absorption distribution metabolism toxicity viruss s However findings COVID1 1 (COVID-1 (SARS-CoV-2 parasulfonatocalix SARS-CoV- (COVID- (SARS-CoV- SARS-CoV (COVID (SARS-CoV

ABSTRACT Desertification is the degradation process caused by climatic conditions and human activities that results in loss of soil productivity and decline in vegetation growth in the long term. Several indices related to vegetation, soil and climate are used to monitor desertification, but few studies explore qualitative and quantitative aspects of indices on desertification on spatial and hierarchical scale. This study aims to identify and measure indices related to increased risk of desertification on global, local and hierarchical scales using multinomial logistic regression models. Images from TM, ETM+ and OLI sensor from 1997 to 2018 in the end of dry and rainy seasons were used to quantify NDVI, TGSI, albedo, temperature, aridity index, evapotranspiration and precipitation on global spatial scale (Irauçuba Centro Norte) and local spatial scale (Miraíma, Canindé, Irauçuba and Santa Quitéria). GISD was calculated by geometric mean of weighted indices and segmented into 8 classes of susceptibility to desertification (hierarchical scale). The results showed that the best models were obtained on local scale and for the end of the rainy season. Temperature proved to be the most important variable for increased risk of desertification on global, local and hierarchical scales. Therefore, the increase in the risk of desertification in the studied areas is due to human activities of deforestation, overgrazing and fire. These factors contributed to reduction of vegetation cover and increase in temperature, changing the microclimatic, which led to decline in precipitation and worsening of desertification. term TM ETM 199 201 NDVI TGSI albedo temperature index Norte Miraíma, Miraíma (Miraíma Canindé Quitéria. Quitéria . Quitéria) scale) season Therefore deforestation fire microclimatic 19 20 1 2

RESUMO O consumo de dióxido de carbono atmosférico pelo intemperismo tampona o efeito estufa na Terra em escala de tempo geológica. Esse mecanismo é chamado de sumidouro de carbono de silicato (SCS). Saprolito representa parte da frente de intemperismo do manto terrestre, mas historicamente não recebeu muita atenção dos geocientistas. Em escala global, o Brasil é o maior contribuinte para o SCS e o quarto maior contribuinte em número de publicações sobre saprolito. Neste estudo, a produção científica brasileira sobre o assunto de 1990 a 2022 foi avaliada, considerando publicações indexadas nas bases de dados Web of Science, SciELO e Scopus. Foram recuperados cento e oitenta artigos científicos. Na última década, sete artigos foram publicados por ano. Ao longo dos 32 anos considerados, o número de artigos sobre saprolito aumentou. A maioria dos estudos foi concentrada na região sudeste do Brasil, onde o estado de Minas Gerais liderou em termos de número de publicações (28,49%). As principais áreas em que os artigos foram publicados estavam relacionadas à ecologia, Terra e marinha; no entanto, foram citados por várias outras, incluindo as áreas de saúde e política. Uma comparação do número de publicações por bacia e o tamanho do SCS mostrou que havia menos estudos da Bacia Amazônica do que da Bacia do Paraná. Em conclusão, a fronteira geográfica para o estudo do saprolito no território brasileiro é a Bacia do Rio Amazonas, e a fronteira metodológica está relacionada à dinâmica de fluídos/gases e ao papel dos micróbios no intemperismo em profundidade. geológica SCS. . (SCS) terrestre geocientistas global 199 202 avaliada Science Scopus científicos década ano 3 considerados aumentou 28,49%. 2849 28,49% 28 49 (28,49%) ecologia marinha entanto outras política Paraná conclusão Amazonas fluídosgases fluídos gases profundidade (SCS 19 20 284 28,49 2 4 (28,49% 1 28,4 (28,49 28, (28,4 (28, (28 (2 (

ABSTRACT The consumption of atmospheric carbon dioxide by weathering buffers the greenhouse effect on Earth on a geological timescale. This mechanism is called the silicate carbon sink (SCS). Saprolite represents part of the weathering front of the Earth’s mantle, but historically, it has not received much attention from geoscientists. On a global scale, Brazil is the largest contributor to the SCS and the fourth largest contributor to the number of saprolite publications. In this study, Brazilian scientific production on the subject from 1990 to 2022 was assessed, considering publications indexed in the Web of Science, SciELO and Scopus databases. One hundred-eighty scientific articles were retrieved. In the last decade, seven articles were published per year. Over the 32 years under consideration, the number of articles on saprolite has increased. Most of the studies were concentrated in the southeastern region of Brazil, where the state of Minas Gerais led in terms of the number of publications (28.49%). The main areas in which the articles were published were related to ecology, Earth, and marine; however, they were cited by several others, including the areas of health and politics. A comparison of the number of publications per basin and the size of the SCS showed that there were fewer studies from the Amazon Basin than from the Paraná Basin. In conclusion, the geographical frontier for the study of saprolite in the Brazilian territory is the Amazon River Basin, and the methodological frontier is related to fluid/gas dynamics and the role of microbes in weathering at depth. timescale SCS. . (SCS) Earths s mantle historically geoscientists scale 199 202 assessed Science databases hundredeighty hundred eighty retrieved decade year 3 consideration increased 28.49%. 2849 28.49% 28 49 (28.49%) ecology marine however others politics conclusion fluidgas fluid gas depth (SCS 19 20 284 28.49 2 4 (28.49% 1 28.4 (28.49 28. (28.4 (28. (28 (2 (

RESUMO Objetivo: Descrever casos de lesão renal aguda (LRA) em crianças diagnosticadas com COVID-19, associando fatores de risco, aspectos clínicos e evolução dos casos. Métodos: Estudo retrospectivo, realizado em hospital pediátrico entre março de 2020 e setembro de 2021, com pacientes com COVID-19 diagnosticados com LRA, que examinou informações presentes em prontuários como comorbidades, idade, sexo e uso de medicações nefrotóxicas. Resultados: Foram estudados 40 casos, sendo o sexo masculino significativamente mais acometido (62,5%; p=0,025). A LRA foi uma complicação grave da infecção por COVID-19, com 100% da amostra necessitando de internação na Unidade de Terapia Intensiva e 22,5% indo a óbito. As comorbidades mais prevalentes analisadas neste estudo foram epilepsia, paralisia cerebral e cardiopatia. A maioria dos pacientes foi classificada pelos critérios Kidney Disease: Improving Global Outcomes (KDIGO) como KDIGO 1 (42,5%) e necessitou de intubação orotraqueal (67,5%). A frequência de uso de medicamentos nefrotóxicos e necessidade de diálise foi baixa, com percentuais de 35 e 17,5%, respectivamente. Entre as crianças que faleceram, 70,4% apresentavam alguma comorbidade e 88,8% receberam ventilação invasiva. Conclusões: A LRA em crianças com infecção por COVID-19 está associada a quadros graves, apesar de a maior parte dos pacientes ter recebido alta hospitalar. Objetivo (LRA COVID19, COVID19 COVID 19, 19 risco Métodos retrospectivo 202 2021 COVID-1 idade nefrotóxicas Resultados 4 62,5% 625 62 5 (62,5% p=0,025. p0025 p p=0,025 . 0 025 p=0,025) 100 225 22 22,5 óbito epilepsia cardiopatia Disease (KDIGO 42,5% 425 42 (42,5% 67,5%. 675 67,5% 67 (67,5%) baixa 3 175 17 17,5% respectivamente faleceram 704 70 70,4 888 88 8 88,8 invasiva Conclusões graves hospitalar COVID1 20 COVID- 62,5 6 (62,5 p002 p=0,02 02 10 2 22, 42,5 (42,5 67,5 (67,5% 17,5 7 70, 88, 62, (62, p00 p=0,0 42, (42, 67, (67,5 17, (62 p0 p=0, (42 (67, (6 p=0 (4 (67 ( p=

ABSTRACT Objective: To describe cases of acute kidney injury (AKI) in children diagnosed with COVID-19, associated risk factors, clinical aspects and outcome of cases. Methods: Retrospective study, carried out in a pediatric hospital between March 2020 and September 2021, with patients with COVID-19 who were diagnosed with AKI, studying information present in medical records such as comorbidities, age, gender and use of nephrotoxic medications. Results: We studied 40 cases, and male individuals were significantly more affected (62.5%; p=0.025). AKI was a severe complication of COVID-19 infection, with 100% of the sample requiring admission to the Intensive Care Unit and 22.5% dying. The most prevalent comorbidities analyzed in this study were epilepsy, cerebral palsy and heart disease. Most patients were classified according to Kidney Disease: Improving Global Outcomes (KDIGO) criteria as KDIGO 1 (42.5%), and required orotracheal intubation (67.5%). The frequency of use of nephrotoxic medications and need for dialysis was low, with percentages of 35 and 17.5%, respectively. Among the children who died, 70.4% had some comorbidity and 88.8% received invasive ventilation. Conclusions: AKI in children with COVID-19 infection is associated with severe conditions. Despite the severity, most patients were discharged alive from the hospital. Objective (AKI COVID19, COVID19 COVID 19, 19 factors Methods 202 2021 COVID-1 age Results 4 62.5% 625 62 5 (62.5% p=0.025. p0025 p p=0.025 . 0 025 p=0.025) 100 225 22 22.5 dying epilepsy disease Disease (KDIGO 42.5%, 425 42.5% , 42 (42.5%) 67.5%. 675 67.5% 67 (67.5%) low 3 175 17 17.5% respectively died 704 70 70.4 888 88 8 88.8 ventilation Conclusions conditions severity COVID1 20 COVID- 62.5 6 (62.5 p002 p=0.02 02 10 2 22. 42.5 (42.5% 67.5 (67.5% 17.5 7 70. 88. 62. (62. p00 p=0.0 42. (42.5 67. (67.5 17. (62 p0 p=0. (42. (67. (6 p=0 (42 (67 ( p= (4

RESUMO Objetivo: descrever a condição miofuncional orofacial global de pacientes com traumatismos faciais e analisar aspectos posturais e de mobilidade relacionados à função deglutição em diferentes etapas de recuperação. Métodos: estudo analítico e transversal. 36 participantes, idade entre 19 e 67 anos. Realizada em cinco etapas (D1, D2, D3, D4 e D5): oitavo ao sexagésimo dia após trauma. Utilizou-se o Protocolo de Avaliação Miofuncional Orofacial com Escores (AMIOFE) adaptado. Foi realizada análise estatística descritiva e inferencial, utilizando os testes t-Student pareado ou teste Wilcoxon pareado e o teste de Friedman na comparação entre as cinco avaliações. A margem de erro utilizada na decisão dos testes estatísticos foi de 5%. Resultados: nos movimentos labiais a maioria (69,4%) tinha inabilidade severa. Nos movimentos da língua, as duas categorias relacionadas, falta de precisão e inabilidade severa, apresentaram percentuais de 52,8% e 41,7%, respectivamente. Na movimentação da mandíbula, a maioria (83,3%) apresentava inabilidade severa. No escore AMIOFE, a mediana foi menos elevada em D1 (29,00), seguida por D2 (33,00), mais elevada em D5 (46,00) e variou de 39,50 a 41,00 nas outras duas avaliações com diferenças significativas entre: D1 diferente de D3, D4 e D5 e D2 diferente de D5. Conclusão: houve evolução positiva espontânea da condição miofuncional orofacial ao longo das avaliações. Contudo, é necessária atenção dos profissionais envolvidos. Objetivo recuperação Métodos transversal 3 participantes 1 6 anos D1, D (D1 D3 D5) trauma Utilizouse Utilizou se AMIOFE (AMIOFE adaptado inferencial tStudent t Student 5 5% Resultados 69,4% 694 69 4 (69,4% severa língua relacionadas 528 52 8 52,8 417 41 7 41,7% respectivamente mandíbula 83,3% 833 83 (83,3% 29,00, 2900 29,00 , 29 00 (29,00) 33,00, 3300 33,00 33 (33,00) 46,00 4600 46 (46,00 3950 39 50 39,5 4100 41,0 Conclusão Contudo envolvidos (D 69,4 (69,4 52, 41,7 83,3 (83,3 290 29,0 2 0 (29,00 330 33,0 (33,00 46,0 460 (46,0 395 39, 410 41, 69, (69, 83, (83, 29, (29,0 33, (33,0 46, (46, (69 (83 (29, (33, (46 (6 (8 (29 (33 (4 ( (2 (3

ABSTRACT Purpose: to describe the global orofacial myofunctional condition of patients presented with facial trauma and analyze postural and mobility aspects related to swallowing function at different stages of recovery. Methods: an analytical and cross-sectional study with 36 participants, aged 19 to 67 years, conducted in five stages (D1, D2, D3, D4, and D5), on the 8th to 60th day after trauma, using the adapted Orofacial Myofunctional Evaluation Protocol with Scores (OMES). Descriptive and inferential statistical analysis was performed using the paired Student's t-test or paired Wilcoxon test, and the Friedman test which compared the five evaluations. A 5% margin of error was used in the decision of the statistical tests. Results: in lip movements, the majority (69.4%) had severe inability. In tongue movements, the two related categories (imprecise and severe inability) had percentages of 52.8% and 41.7%, respectively. In jaw movements, the majority (83.3%) had severe inability. The median OMES score was lowest in D1 (29.00), followed by D2 (33.00), highest in D5 (46.00), and ranged from 39.50 to 41.00 in the other two evaluations, with significant differences between D1 and D3, D4 and D5, and D2 and D5. Conclusion: the orofacial myofunctional condition progressed, spontaneously and positively, throughout the evaluations. However, attention is needed from the professionals involved. Purpose recovery Methods crosssectional cross sectional 3 participants 1 6 years D1, D (D1 D3 , D5) th OMES. . (OMES) Students Student s ttest t evaluations 5 tests Results movements 69.4% 694 69 4 (69.4% inability imprecise 528 52 8 52.8 417 41 7 41.7% respectively 83.3% 833 83 (83.3% 29.00, 2900 29.00 29 00 (29.00) 33.00, 3300 33.00 33 (33.00) 46.00, 4600 46.00 46 (46.00) 3950 39 50 39.5 4100 41.0 Conclusion progressed positively However involved (D (OMES 69.4 (69.4 52. 41.7 83.3 (83.3 290 29.0 2 0 (29.00 330 33.0 (33.00 460 46.0 (46.00 395 39. 410 41. 69. (69. 83. (83. 29. (29.0 33. (33.0 46. (46.0 (69 (83 (29. (33. (46. (6 (8 (29 (33 (46 ( (2 (3 (4

This study offers a comprehensive analysis of how governance capacities in developing countries respond to the challenges that COVID-19 posed. We established a theoretical framework to delve into the multifaceted nature of governance capacities, exploring two distinct aspects of governance: the Weberian one, which focuses on material and organizational capacities, and the Tocquevillian one, which focuses on coordination and associational capacities. We examined these four governance dimensions to illustrate how these distinct skills influence the effectiveness of governance. Our analysis quantifies the impact of the COVID-19 pandemic using such metrics as confirmed cases and deaths. We employ standard and dynamic panel data methodologies to mitigate potential omitted variable bias. Our research findings indicate that countries with robust governance capacities, as assessed by the Bertelsmann Stiftung's Transformation Governance Index, are better equipped to respond effectively to pandemic crises. By applying several models and rigorous robustness tests, we demonstrate efficient resource utilization, the ability to guide and prioritize decision-making within the government, and commitment to cooperation and coordination with other nations and international organizations are the primary drivers of improved outcomes. Our findings remain robust even when controlling for relevant variables and employing estimation techniques that account for potential biases arising from unobservable confounding factors. COVID19 COVID 19 COVID-1 posed one deaths bias Stiftungs Stiftung s Index crises tests utilization decisionmaking decision making government outcomes factors COVID1 1 COVID-

RESUMO A busca por novas tecnologias capazes de proporcionar benefícios para uma alimentação saudável tem sido meta mundial. A presença de alimentos ricos em carotenoides pode ser fundamental para prevenir sérios problemas de saúde. Aliar alimentos com altos teores de carotenoides e acessíveis para a maior parte da população é fundamental. A alface (Lactuca sativa L.) se apresenta como uma espécie adequada para investir em pesquisas com biofortificação a partir de melhoramento genético. Assim, o objetivo com este estudo foi selecionar híbridos de alface visando à obtenção de populações com potencial agronômico e biofortificadas para carotenoides. Dez linhagens de alface cadastradas no Software “BG α Biofort” foram utilizadas nas hibridações. Os cruzamentos para obtenção dos híbridos foram planejados envolvendo duas linhagens ricas em pelo menos um dos pigmentos (clorofila e carotenoides) sendo obtidos 24 híbridos experimentais. Foram avaliados 37 genótipos (linhagens, híbridos e cultivares comercias) em delineamento em blocos casualizados quanto as variáveis agronômicas e teores de clorofila e carotenoides. Foi verificado que os híbridos 12 (UFU-189#3#4#1 × UFU MC BIOFORT 2) e 25 (UFU66#4#2 × UFU-189#3#4#1) possuem potencial para obtenção de populações de duplo propósito (produtividade e biofortificada para carotenoide). O híbrido 27 (UFU66#4#2 × UFU MC BIOFORT1) foi o que apresentou maior equilíbrio para pigmentos. Sugere-se a obtenção de populações F2 dos híbridos 12, 25 e 27 visando a obtenção de novas cultivares de alfaces biofortificadas vermelhas e verdes, para os segmentos de alface crespa, americana, mini e romana. mundial saúde Lactuca L. L genético Assim BG Biofort hibridações 2 experimentais 3 linhagens, (linhagens comercias 1 UFU189#3#4#1 UFU189341 189#3#4#1 189 4 (UFU-189#3#4# UFU66#4#2 UFU6642 UFU66 (UFU66#4# UFU-189#3#4#1 produtividade carotenoide. carotenoide . carotenoide) BIOFORT1 Sugerese Sugere F verdes crespa americana romana UFU189 UFU189#3#4# UFU18934 189341 189#3#4# 18 (UFU-189#3#4 UFU66#4# UFU664 UFU6 (UFU66#4 UFU-189#3#4# UFU18 UFU189#3#4 UFU1893 18934 189#3#4 (UFU-189#3# UFU66#4 (UFU66# UFU-189#3#4 UFU1 UFU189#3# 1893 189#3# (UFU-189#3 UFU66# (UFU66 UFU-189#3# UFU189#3 189#3 (UFU-189# (UFU6 UFU-189#3 UFU189# 189# (UFU-189 (UFU UFU-189# (UFU-18 UFU-189 (UFU-1 UFU-18 (UFU- UFU-1 UFU-

ABSTRACT The search for new technologies capable of providing benefits to healthy eating is a global goal. The consumption of foods rich in carotenoids can prevent serious health problems. Thus, the availability of foods high in carotenoids that are accessible to the majority of the population is essential. Lettuce (Lactuca sativa L.) is a suitable species for biofortification research based on genetic improvements. In this study, we aimed to select and obtain hybrid lettuce populations with high agronomic potential and biofortified carotenoid content. Ten lettuce lines registered in the “BG α Biofort” software were selected for hybridization. The crosses used to obtain the hybrids involved two strains rich in at least one of the pigments (chlorophyll and carotenoids), and 24 experimental hybrids were obtained. A total of 37 genotypes (strains, hybrids, and commercial cultivars) were evaluated using a randomized block design for agronomic variables and chlorophyll and carotenoid content. Hybrids 12 (UFU-189#3#4#1 × UFU MC BIOFORT 2) and 25 (UFU66#4#2 × UFU-189#3#4#1) had the potential to produce dual-purpose populations (yield and carotenoid biofortification). Hybrid 27 (UFU66#4#2 × UFU MC BIOFORT1) exhibited the best pigment balance. Thus, F2 hybrids 12, 25, and 27 should be obtained to produce new cultivars of biofortified red and green lettuce for curly, american, mini, and romaine lettuce segments. goal problems Thus essential Lactuca L. L improvements study content BG Biofort hybridization carotenoids, , carotenoids) 2 3 strains, (strains 1 UFU189#3#4#1 UFU189341 189#3#4#1 189 4 (UFU-189#3#4# UFU66#4#2 UFU6642 UFU66 (UFU66#4# UFU-189#3#4#1 dualpurpose dual purpose yield biofortification. . biofortification) BIOFORT1 balance F curly american mini segments UFU189 UFU189#3#4# UFU18934 189341 189#3#4# 18 (UFU-189#3#4 UFU66#4# UFU664 UFU6 (UFU66#4 UFU-189#3#4# UFU18 UFU189#3#4 UFU1893 18934 189#3#4 (UFU-189#3# UFU66#4 (UFU66# UFU-189#3#4 UFU1 UFU189#3# 1893 189#3# (UFU-189#3 UFU66# (UFU66 UFU-189#3# UFU189#3 189#3 (UFU-189# (UFU6 UFU-189#3 UFU189# 189# (UFU-189 (UFU UFU-189# (UFU-18 UFU-189 (UFU-1 UFU-18 (UFU- UFU-1 UFU-