Abstract (Introduction): Within the framework of the present capitalist system, human beings have become an important polluting agent. Current production and consumption processes do not consider the existence of finite natural resources and a planet incapable of treating the waste that the prevailing way of life generates. Given these circumstances, the study of non-linear models is of interest, which make a more rational use of the waste that the productive activity generates, favoring recycling mechanisms. The phenomenon of recycling becomes particularly relevant in the case of electrical and electronic devices, whose ability to be degraded and metabolized by planet Earth is extremely difficult. (Objective): Evaluate the feasibility of installing and starting a recycling plant for electrical and electronics items in the town of Bahía Blanca (Argentina), during 2021. (Methodology): The conventional method for evaluating investment projects was used, considering technical, legal and economic aspects. (Results): The project is not acceptable according to the profitability intended by the investor. The possibility of financing was also included, which made the project even less profitable, and the sensitivity of the results was measured, finding that the price should be 1.48 % higher than that used in the analysis. (Conclusions): Other alternatives must be explored to make this proposal profitable from an economic and financial point of view.

Resumen (Introducción): En el marco del sistema capitalista vigente, el ser humano se ha transformado en un agente significativo de contaminación. Las dinámicas productivas y de consumo actuales no contemplan la existencia de recursos naturales finitos y de un planeta incapaz de procesar los desperdicios que el modo de vida habitual genera. Dadas estas circunstancias, cobra interés el estudio de modelos no lineales, que hagan un uso más racional de los residuos derivados de la actividad productiva, los cuales favorezcan mecanismos de reciclaje. El fenómeno del reciclaje se vuelve, en particular, relevante para el caso de los artefactos eléctricos y electrónicos; la capacidad del planeta Tierra para degradarlos y metabolizarlos resulta sumamente difícil. (Objetivo): Evaluar la factibilidad de la instalación y puesta en marcha de una planta recicladora de artículos eléctricos y electrónicos en la localidad de Bahía Blanca (Argentina), durante el 2021. (Metodología): Se utilizó la metodología convencional de evaluación de proyectos de inversión, considerando aspectos técnicos, legales y económicos. (Resultados): El proyecto no es aceptable según la rentabilidad pretendida por el inversor. También se incluyó la posibilidad de un financiamiento, lo que hizo que el plan fuera menos rentable aún, y se midió la sensibilidad de los resultados: se halló que el precio debiera ser 1.48 % superior al utilizado en el análisis. (Conclusiones): Se deben explorar otras alternativas para lograr que el proyecto sea rentable desde el punto de vista económico-financiero.

Parthenolide (PTN) is a secondary metabolite of the plant Tanacetum parthenium (L.) Schulz Bip. and is considered the chemical marker of this species. This sesquiterpene lactone (germacrene skeleton) has been described as responsible for the biological activity of the leaf extract. In addition, several studies in the literature have demonstrated its antiparasitic and antineoplastic activity. However, there is a need for knowledge of other safety parameters, such as pharmacokinetic, pharmacodynamic and toxicity evaluations. Therefore, in this investigation, the in vitro metabolism of parthenolide was performed with rat liver microsomes and biomimetic metabolism (such as cytochrome P-450 system) using organometallic catalysts. The biomimetic procedure was validated since the major compound of biomimetic oxidative reaction with meta-chloroperbenzoic acid catalyzed by metalloporphyrin 5,10,15,20-tetrakis(pentafluorophenyl)-porphyrin iron(III) chloride was also observed with rat liver microsomes. Previous chemoenzymatic synthesis studies of PTN afforded the same epoxide formation, this major oxidative compound was isolated and fully characterized as (1 R,10R)-epoxyparthenolide based on experimental and theoretical calculations of infrared (IR) and vibrational circular dichroism (VCD) data at the B3PW91/6-311G. Furthermore, for the first time, this metabolite was evaluated for trypanocidal and leishmanicidal activity. The mean inhibitory concentration (IC50) values were lower for PTN than its metabolite and showed significant cytotoxic effects for both parasites. This finding holds promise for addressing neglected diseases. (PTN L. L (L. Bip species germacrene skeleton extract addition However parameters pharmacokinetic evaluations Therefore investigation P450 P 450 P-45 system catalysts metachloroperbenzoic meta chloroperbenzoic 5,10,15,20tetrakispentafluorophenylporphyrin 5101520tetrakispentafluorophenylporphyrin tetrakispentafluorophenylporphyrin 5,10,15,20 tetrakis pentafluorophenyl porphyrin 5 10 15 20 ironIII iron III iron(III formation 1 ( R,10Repoxyparthenolide R10Repoxyparthenolide RRepoxyparthenolide R,10R epoxyparthenolide R 10R IR (IR VCD (VCD B3PW91/6311G. B3PW916311G BPWG B3PW91/6 311G. B3PW91 6 311G B PW G B3PW91/6-311G Furthermore time IC50 IC (IC50 parasites diseases (L P45 45 P-4 20tetrakispentafluorophenylporphyrin 5101520 5,10,15,2 2 10Repoxyparthenolide Repoxyparthenolide R10R RR 6311G B3PW91/6311G B3PW916 BPW B3PW91/ B3PW9 IC5 (IC5 P4 4 P- 510152 5,10,15, B3PW (IC 51015 5,10,15 5101 5,10,1 510 5,10, 51 5,10 5,1 5,

ABSTRACT Introduction/framework/objectives Multiple Sclerosis has a reasonable prevalence and the diagnosis is generally made at working age, at a stage that is still demanding on a professional level, a time when there are also generally personal/family particularities that require some dedication. Furthermore, given the incidence, diversity and severity of the symptoms presented, limitations often arise that can seriously affect the ability to work or even lead to unemployment. It is then desirable that the members working in Occupational Health and Safety teams have some knowledge on the subject, in order to better guide their performance, safeguarding the interests of everyone involved. Methodology This is a Bibliographic Review, initiated through a search carried out in April 2023, in the databases “CINALH plus with full text, Medline with full text, Database of Abstracts of Reviews of Effects, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, Cochrane Methodology Register, Nursing and Allied Health Collection: comprehensive, MedicLatina and RCAAP”. Content It is a demyelinating and autoimmune disease of the Central Nervous System; it is characterized by recurrent and intermittent episodes of inflammation, with generally progressive destruction of axonal myelin. In most cases there is a cycle of relapses and remissions and symptoms of varying intensity; the evolution is unpredictable. Causes autonomic, visual, motor and sensory symptoms; which makes independent daily living and the ability to work difficult; sometimes becoming debilitating. It is incurable and neurodegenerative. The severity varies depending on the neurological areas most affected. The function of myelin is to facilitate conduction at the level of axons; with changes in this, the electrical impulses that coordinate mental and physical functions become less effective. As myelin deteriorates, it is replaced by scars of abnormal tissue, with different consistency (stiffness, plaques), which further disrupts conduction. Injuries to the frontal and parietal lobes often result in cognitive and emotional changes; in the spinal cord, problems arise more easily in the lower limbs. Changes in the optic nerve and occipital lobe can cause visual problems. This is the neurological desease that causes most limitations in the young adult active population. Given the reasonably young age at which symptoms begin, there will be a decrease in quality of life, more significant than in other chronic diseases. Discussion and Conclusions Although the bibliography is not scarce, the emphasis in the vast majority of articles is not on Occupational Health or Safety. It would be relevant for some teams working in large companies with some prevalence, to evaluate the cases in detail, describing the main problems detected, proposed measures and their subsequent evaluation, in order to publish not only the path, but also the conclusions obtained, for greater dissemination of the subject.

RESUMO Introdução/enquadramento/objetivos A Esclerose Múltipla tem uma prevalência razoável e o diagnóstico faz-se geralmente em idade ativa, numa fase ainda exigente a nível profissional, altura essa onde geralmente também existem particularidades pessoais/familiares que necessitam de alguma dedicação. Para além disso, dada a incidência, diversidade e gravidade dos sintomas apresentados, com frequência surgem limitações que podem condicionar seriamente a capacidade de trabalho ou até levar ao desemprego. Será então desejável que os elementos a exercer em equipas de Saúde e Segurança Ocupacionais tenham alguns conhecimentos sobre o tema, de forma a melhor orientar o seu desempenho, salvaguardando os interesses de todos os envolvidos. Metodologia Trata-se de uma Revisão Bibliográfica, iniciada através de uma pesquisa realizada em abril de 2023, nas bases de dados “CINALH plus with full text, Medline with full text, Database of Abstracts of Reviews of Effects, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, Cochrane Methodology Register, Nursing and Allied Health Collection: comprehensive, MedicLatina e RCAAP”. Conteúdo É uma doença desmielinizante e auto-imune do Sistema Nervoso Central; carateriza-se por episódios recorrentes e intermitentes de inflamação, com destruição de mielina axonal, geralmente progressiva. Na maioria dos casos existe um ciclo de relapsos e remissões e sintomas de intensidade oscilante; a evolução é imprevisível. Causa sintomas autonómicos, visuais, motores e sensoriais; o que dificulta a vida quotidiana independente e o trabalho, tornando-se por vezes debilitante. É incurável e neurodegenerativa. A gravidade varia com as áreas neurológicas mais atingidas. À medida que a mielina se detiora, ela é substituída por cicatrizes de tecido anormal, com diferente consistência (rigidez, placas), o que perturba ainda mais a condução. Lesões nos lóbulos frontal e parietal geralmente resultam em alterações cognitivas e emocionais; na espinal medula, mais facilmente surgem problemas nos membros inferiores. Alterações no nervo ótico e lobo occipital podem originar alterações visuais. Trata-se da doença neurológica que mais limitações causa na população ativa jovem adulta. Dada a idade razoavelmente jovem do início de sintomas, irá ocorrer diminuição da qualidade de vida, mais significativa que noutras doenças crónicas. Discussão e Conclusões Ainda que a bibliografia não seja escassa, a enfase da grande maioria dos artigos não é dada à Saúde ou Segurança Ocupacionais. Seria relevante que algumas equipas a exercer em empresas grandes e com alguma incidência, avaliassem com detalhe os casos, descrevendo os principais problemas detetados, medidas propostas e avaliação posterior das mesmas, de forma a publicar não só o caminho, mas também as conclusões obtidas, para maior divulgação do assunto.

Resumen El mapeo geológico es una herramienta fundamental en la exploración y el aprovechamiento de recursos minerales. Desde escalas regionales hasta locales, es usado en proyectos mineros para identificar el recurso mineral, modelar el depósito, orientar perforaciones, planificar la extracción del mineral, en el diseño de mina y, en la evaluación de riesgos e impactos ambientales. Es decir, está presente en todo el ciclo de vida del proyecto minero. Para entender las relaciones que existen entre los datos obtenidos de diversas disciplinas asociadas a la geología como geofísica, geoquímica, petrografía, geología estructural, etc., es adecuado que estos sean tratados como un sistema de folios. Mediante una investigación bibliográfica se presenta la importancia del uso de esta metodología. En particular, el sistema de folios Anaconda, cuyos procedimientos estandarizados han permitido obtener buenos resultados en la exploración o explotación de minerales en Yerington-EEUU, La Costanaza-España, Ferrobamba-Perú, Guanajuato-México, Imbabura-Ecuador y Atacama-Chile.

Abstract Geological mapping is a fundamental tool in the exploration and development of mineral resources. From regional to local scales, it is used in mining projects to identify the mineral resource, to model the deposit, to guide drilling, to plan mineral extraction, in mine design, and in the evaluation of risks and environmental impacts. In other words, it is present throughout the life cycle of the mining project. To understand the relationships that exist between the data obtained from various disciplines associated with geology, such as geophysics, geochemistry, petrography, structural geology, etc., it is appropriate that these be treated as a layers’ system. The importance of the use of this methodology is presented by means of bibliographic research. In particular, the Anaconda system, whose standardized procedures have allowed to obtain good results in the exploration or exploitation of minerals in Yerington-USA, La Costanaza-Spain, Ferrobamba-Peru, Guanajuato-Mexico, Imbabura-Ecuador, Atacama-Chile.

Summary: Bioestimulants such as chitosan in traditional agriculture have proven effective in promoting plant growth and development, as well as protecting them from diseases. However, in aquaponic production systems its effect is not documented, therefore the objective of the present work was to determine the effect of chitosan concentration (0, 500 and 1000 mg L-1) in three varieties (Great Lakes, Regina 500 and Red Rock) of lettuce (Latuca sativa L.), on production parameters in a circular aquaponics system. Using a completely randomized design with a 3×3 factorial arrangement, chitosan was applied by spraying at 10 and 45 days after transplantation. After the analysis of variance, the differences due to the variety were determined using the Tukey test and the effect of chitosan concentration through orthogonal polynomials, in addition to a correlation analysis and simple linear regression between the yield, height, number and length of the leaves. The results showed that the variables number of leaves, length of leaves and root, plant weight, plant height and yield increased as the dose of chitosan increased. The Red Rock variety outperformed the Regina 500 and Great Lakes varieties. No presence of insects or diseases was detected. It is concluded that chitosan favors the growth, development and yield of the lettuce plant in a circular aquaponic system, especially with doses of 1000 mg L-1 of chitosan, and that with respect to these same variables, the Red Rock variety surpasses to the Regina 500 and Great Lakes varieties.

Resumen: Los bioestimulantes como el quitosano en la agricultura tradicional han demostrado su eficacia para promover el crecimiento y desarrollo de las plantas, así como protegerlas de enfermedades. Sin embargo, en sistemas de producción acuapónicos su efecto no está documentado, por ello el objetivo del presente trabajo fue determinar el efecto de la concentración de quitosano (0, 500 y 1000 mg L-1) en tres variedades (Grandes Lagos, Regina 500 y Red Rock) de lechuga (Latuca sativa L.), sobre los parámetros de producción en un sistema circular de acuaponía. Utilizando un diseño completamente al azar con un arreglo factorial 3×3 el quitosano se aplicó mediante aspersión a los 10 y 45 días después del trasplante. Posterior al análisis de varianza, las diferencias debido a la variedad se determinaron utilizando la prueba de Tukey y, el efecto de la concentración de quitosano mediante polinomios ortogonales, además de un análisis de correlación y regresión lineal simple entre el rendimiento, altura, número y longitud de las hojas. Los resultados demostraron que las variables número de hojas, longitud de hojas y raíz, peso de planta, altura de planta y rendimiento, se incrementó conforme se aumentó la dosis de quitosano. La variedad Red Rock superó a las variedades Regina 500 y Grandes Lagos. No se detectó la presencia de insectos ni enfermedades. Se concluye que el quitosano favorece el crecimiento, desarrollo y rendimiento de la planta de lechuga en un sistema circular de acuaponía, sobre todo con dosis de 1000 mg L-1 de quitosano, y que respecto a estas mismas variables, la variedad Red Rock supera a las variedades Regina 500 y Grandes Lagos.

Abstract: This investigation proposes to develop a methodology based on the mean-variance mapping optimization (MVMO) algorithm to reduce the active power losses of the subtransmission system of the Electric Company Quito (EEQ), determining the best operating point of the system, considering the state of taps of the transformers, the capacitor banks and the contribution of reagents from the generation plants that the company currently has. EEQ. The same ones that, when operating in an adequate manner, lead to reducing the value of active power losses in the network, thus improving the operating conditions of the EEQ Electrical Power System.

Resumen: Esta investigación propone desarrollar una metodología basada en el algoritmo de optimización de mapeo media varianza (MVMO) para reducir las pérdidas de potencia activa del sistema de subtransmisión de la Empresa Eléctrica Quito (EEQ), determinando el mejor punto de operación del sistema, considerando el estado de tap’s de los transformadores, los bancos de capacitores y del aporte de reactivos de las centrales de generación con las que cuenta actualmente la EEQ. Los mismos que al operar de una manera adecuada llevan a reducir el valor de las pérdidas de potencia activa en la red, mejorando así las condiciones operativas del Sistema Eléctrico de Potencia de la EEQ.

Abstract: This study addresses the application of the Cross-Industry Standard Process for Data Mining (CRISP-DM) methodology in the analysis of dissolved gases in oil of power transformers, being this a critical component in electrical systems. The adoption of this six-phase structured method allowed a comprehensive evaluation of the condition of the transformer units of the Ecuadorian electrical system based on the analysis of investment and expansion data of the sector, as well as the study of 1 099 DGA (Dissolved Gas Analysis) profiles obtained from a population of 153 transformers located in the different regions of continental Ecuador. The findings described in this work have the potential to significantly improve investment and maintenance strategies and policies. In addition, the adoption of automation techniques in the DGA classification process is proposed, using supervised learning models to enhance the reliability and efficiency of the public energy service. The results suggest that this approach not only improves the diagnosis within the maintenance activities, but also provides a solid basis to draw a roadmap towards a predictive asset management, resulting in a substantial improvement of the reliability of the national power system.

Resumen: Este estudio aborda la aplicación de la metodología Cross-Industry Standard Process for Data Mining (CRISP-DM) en el análisis de los gases disueltos en aceite de transformadores de potencia, siendo este un componente crítico en los sistemas eléctricos. La adopción de este método estructurado de seis fases permitió evaluar de forma integral la condición de las unidades de transformación del sistema eléctrico ecuatoriano a partir del análisis de datos de inversión y expansión del sector, así como del estudio de 1 099 perfiles DGA (Dissolved Gas Analysis) obtenidos de una población de 153 transformadores ubicados en las distintas regiones de Ecuador continental. Los hallazgos descritos en este trabajo tienen el potencial de mejorar significativamente las estrategias y políticas de inversión y mantenimiento. Además, se propone la adopción de técnicas de automatización en el proceso de clasificación DGA, utilizando modelos de aprendizaje supervisado para potenciar la confiabilidad y eficiencia del servicio público de energía. Los resultados sugieren que este enfoque no solo mejora el diagnóstico dentro de las actividades de mantenimiento, sino que también proporciona una base sólida para trazar una hoja de ruta hacia una gestión predictiva de los activos, lo que se traduce en una mejora sustancial de la confiabilidad del sistema eléctrico nacional.

Abstract: The Galapagos Islands present distinctive challenges in managing their electrical system due to their remote geographical position. Currently, their energy sources are limited to non-renewable energy and partially dependent on renewable energy sources like wind and solar power. The intermittence of these sources poses a threat to the stability and reliability of power systems. The battery energy storage systems (BESS) are a commonly adopted approach for promoting the stability of frequency and voltage in power systems. However, the effectiveness of these systems in accomplishing this objective is contingent on the type of controller and operation used in the storage system. Electrical energy storage systems implement two primary modes of operation; Grid Following and Grid Forming. This paper focuses on the implementation and evaluation in different scenarios of the network-forming mode of operation of the storage system, with the purpose of contributing to the primary frequency regulation in the MRE of the Galapagos Islands. The results obtained demonstrate significant improvements in the stability of the MRE, and greater efficiency in primary frequency regulation.

Resumen: Las Islas Galápagos, debido a su ubicación geográfica aislada, enfrentan desafíos únicos en la gestión de su Microrred eléctrica (MRE), pues actualmente depende de energías no renovables y en una medida considerable de fuentes de energías renovables, como la energía solar y eólica. Estas fuentes de energía intermitentes, afectan la confiabilidad y estabilidad de la MRE. Una solución destacada en la actualidad es la implementación de los sistemas de almacenamiento de energía con baterías, pues estos sistemas aportan a la estabilidad de frecuencia y voltaje, sin embargo, estos aportes a la estabilidad de frecuencia y voltaje de la MRE están en función del tipo de controlador y operación que se emplee al sistema de almacenamiento. Existen dos modos de operación en sistemas almacenamiento de energía eléctrica; seguidor de red y formador de red. Este trabajo se enfoca en la implementación y evaluación en diferentes escenarios, del modo de operación formador de red del sistema de almacenamiento, con el propósito de aportar a la regulación primaria de frecuencia en la MRE de las Islas Galápagos. Los resultados obtenidos demuestran las mejoras significativas en la estabilidad de la MRE, y una mayor eficiencia en la regulación primaria de frecuencia.

Abstract: This study analyzes the experiences of 17 Colombian primary education teachers in caring for students with disabilities, registered in 17 educational institutions in 11 municipalities between 2018 and 2022. Through a narrative design and a questionnaire with open-ended questions, the interactions of these teachers with the educational environment were explored. Twelve psychological and thirteen pedagogical factors were identified, and their impact was examined depending on the types of disabilities and the specific characteristics of the students and educational contexts. The results reveal high variability and subjectivity in these factors, which can both favor and hinder inclusive educational practices. Additionally, the study examines the Individual Plan for Reasonable Adjustments, highlighting significant deficiencies in its implementation and resistance from some school sectors. This underscores challenges in adopting the inclusive education model promoted by the Colombian State. This analysis provides valuable insights for the continuous improvement of inclusive practices in the Colombian educational system

Resumen: Este estudio analiza las experiencias de 17 docentes colombianos de educación primaria en la atención a estudiantes con discapacidad, registradas en 17 instituciones educativas de 11 municipios entre 2018 y 2022. Mediante un diseño narrativo y un cuestionario de preguntas abiertas, se exploraron las interacciones de estos docentes con el entorno educativo. Se identificaron 12 factores psicológicos y 13 pedagógicos y se examinó su impacto en función de los tipos de discapacidad y las características específicas de los estudiantes y contextos educativos. Los resultados revelan una alta variabilidad y subjetividad en estos factores, los cuales pueden ser tanto favorecedores como obstaculizadores de las prácticas educativas inclusivas. Adicionalmente, el estudio examina el Plan Individual de Ajustes Razonables, destacando deficiencias significativas en su implementación y resistencia por parte de algunos sectores escolares, lo cual subraya desafíos en la adopción del modelo de educación inclusiva promovido por el Estado colombiano. Este análisis proporciona insights valiosos para la mejora continua de las prácticas inclusivas en el sistema educativo colombiano

Resumo: Este estudo analisa as experiências de 17 docentes colombianos do ensino primário no atendimento a alunos com deficiência, matriculados em 17 instituições de ensino em 11 municípios entre 2018 e 2022. Por meio de um desenho narrativo e de um questionário de perguntas abertas, foram exploradas as interações destes professores com o ambiente educacional. Foram identificados 12 fatores psicológicos e 13 pedagógicos e o seu impacto foi examinado em função dos tipos de deficiência e das características específicas dos estudantes e dos contextos educativos. Os resultados revelam alta variabilidade e subjetividade nesses fatores, o que pode favorecer ou dificultar práticas educativas inclusivas. Além disso, o estudo examina o Plano Individual de Ajustes Razoáveis, destacando falhas significativas na sua implementação e resistência por parte de alguns setores escolares, o que salienta desafios na adoção do modelo de educação inclusiva promovido pelo Estado colombiano. Esta análise fornece insights valiosos para a melhoria contínua das práticas inclusivas no sistema educacional colombiano

Resumo: Apresenta-se uma análise bibliométrica baseada em artigos de pesquisa publicados entre 2010 e 2022 para responder à pergunta: Como são organizados os conteúdos de ensino nas ciências naturais e quais são seus fundamentos teóricos e metodológicos? A busca foi realizada nas bases de dados SciELO, Dialnet, Scopus, ProQuest e no motor de busca Google Scholar, utilizando as seguintes palavras-chave: sequências de ensino e aprendizagem, sequência de ensino, sequência de aprendizagem, proposta didática, proposta de ensino, estratégia didática, unidade didática, sequência didática, experiência de sala de aula, projeto de aula, sistema didático e ciências naturais (biologia, física, química, astronomia e geologia). Foram encontrados 85 artigos, para cuja análise foram estabelecidas três categorias: 1) características gerais dos artigos, 2) natureza das experiências propostas e 3) elementos mediadores na construção. Foi estabelecido que os sistemas de organização de conteúdo mais comumente implementados são "sequência de ensino e aprendizagem", "sequência didática" e "unidade didática", e foi observado que os docentes estão começando a considerar os contextos e as realidades dos alunos, tanto em termos de conteúdo quanto de estratégias. Também foram estabelecidos elementos importantes para os docentes na elaboração da organização do conteúdo: a história da ciência, as habilidades cognitivo-linguísticas, as novas tecnologias informáticas e a avaliação

Resumen: Se presenta un análisis bibliométrico realizado con base en trabajos de investigación publicados entre el año 2010 y 2022 para responder a la pregunta: ¿Cómo se organizan los contenidos objeto de enseñanza en las ciencias naturales y en qué se fundamentan teórica y metodológicamente? La búsqueda se hizo en las bases de datos SciELO, Dialnet, Scopus, ProQuest y el buscador Google Académico usando las siguientes palabras clave: secuencias de enseñanza y aprendizaje, secuencia de enseñanza, secuencia de aprendizaje, propuesta didáctica, propuesta de enseñanza, estrategia didáctica, unidad didáctica, secuencia didáctica, experiencia de aula, proyecto de aula, sistema didáctico y ciencias naturales (biología, física, química, astronomía y geología). Se encontraron 85 artículos para cuyo análisis se establecieron tres categorías: 1) características generales de los artículos, 2) naturaleza de las experiencias planteadas y 3) elementos mediadores en la construcción. Se estableció que los sistemas de organización de contenidos mayormente implementados son “secuencia de enseñanza y aprendizaje”, “secuencia didáctica” y “unidad didáctica” y se observó que los docentes comienzan a considerar los contextos y realidades del estudiantado, tanto en contenidos como en estrategias. También se establecieron elementos importantes para los docentes a la hora de diseñar una organización de contenidos: la historia de las ciencias, las habilidades cognitivo-lingüísticas, las nuevas tecnologías informáticas y la evaluación

Abstract: This paper presents a bibliometric analysis based on research studies published between 2010 and 2022 to address the question: How are the contents of natural sciences teaching organized, and what are their theoretical and methodological foundations? The search was conducted in the SciELO, Dialnet, Scopus, ProQuest, and Google Scholar databases using the following keywords: teaching and learning sequences, teaching sequence, learning sequence, didactic proposal, teaching proposal, didactic strategy, didactic unit, didactic sequence, classroom experience, classroom project, didactic system, and natural sciences (biology, physics, chemistry, astronomy, and geology). A total of 85 articles were found and analyzed according to three categories: 1) general characteristics of the articles, 2) the nature of the proposed experiences, and 3) mediating elements in the construction. The study established that the most commonly implemented content organization systems are "teaching and learning sequence," "didactic sequence," and "didactic unit." It was also observed that teachers are increasingly considering the contexts and realities of students in both content and strategies. Additionally, important elements were identified for teachers when designing content organization, including the history of sciences, cognitive-linguistic skills, new information technologies, and evaluation

Abstract Introduction: The Mar Muerto lagoon is an ecosystem characterized by high productivity upon which various inhabiting organisms depend. Additionally, it is a system susceptible to environmental impacts. Consequently, indices have been developed to determine the degree of disturbance caused by natural and/or anthropogenic factors. Objective: To assess the degree of disturbance in the Mar Muerto lagoon using a Biotic Integrity Index (BII) based on ichthyofauna. Methods: From December 2019 to March 2021, 12 sampling stations were established in the lagoon. The Biotic Integrity Index was developed by collecting data on hydrological variables (salinity, dissolved oxygen, pH, electrical conductivity, suspended solids, temperature, nitrites, nitrates, phosphates, and transparency) and classifying fish species based on their composition and richness. This was followed by a Water and Habitat Quality Index (WHQI) derived from the characterization and classification of sampling stations based on physicochemical variables. The correlation of the two indices allowed for the evaluation of the effectiveness of the BII. Results: 65 species were reported for the lagoon, with Lile gracilis, Oligoplites altus, Eucinostomus currani, and Gerres simillimus being the most frequently recorded. Only station 10 exhibited poor biotic integrity (BII = 26), while the rest displayed regular biotic integrity (BII = 30 - 44), with station nine presenting the highest calculated value (BII = 42). The assessment of the lagoon’s BII demonstrated an average biotic integrity considered “regular.” Conclusion: Through this study, the functionality of the modified BII for the Mar Muerto lagoon was verified, allowing for the evaluation of the present conservation status and comparison with previous studies.

Resumen Introducción: La laguna Mar Muerto es un ecosistema caracterizado por una gran productividad, de la cual dependen diversos organismos que la habitan; también es un sistema susceptible a impactos ambientales. Por lo anterior, se han desarrollado índices que permiten conocer el grado de alteración por causas naturales y/o antropogénicas. Objetivo: Evaluar el grado de perturbación de la laguna Mar Muerto, mediante un índice de integridad biótica (IBI) basado en la ictiofauna. Métodos: De diciembre 2019 a marzo 2021, se establecieron 12 estaciones de muestreo en la laguna. La elaboración del índice de integridad biótica fue a partir de la recopilación de datos de las variables hidrológicas (salinidad, NO2, NO3, PO4, pH, OD, T, CE, transparencia y SDT) y la clasificación de las especies ícticas según su composición y riqueza; seguido de un índice de calidad de agua y hábitat (ICAH), elaborado a partir de la caracterización y clasificación de las estaciones de muestreo en función de variables fisicoquímicas. La correlación de los dos índices permitió evaluar la efectividad del IBI. Resultados: 65 especies fueron reportadas para la laguna, de las cuales Lile gracilis, Oligoplites altus, Eucinostomus currani y Gerres simillimus se registraron con mayor frecuencia. Sólo la estación 10 presentó una integridad biótica pobre (IBI = 26), el resto presentó un IBI regular (IBI = 30 - 44), siendo la estación nueve la que presentó el valor máximo calculado (IBI = 42). La valoración del IBI de la laguna demostró que ésta presenta una integridad biótica promedio considerada “regular”. Conclusión: A través de este trabajo, se comprobó la funcionalidad del IBI modificado para la laguna Mar Muerto, permitiendo evaluar el grado de conservación presente y compararlo con trabajos previos.

Abstract: This study proposes a model to evaluate the impact of a quality management system on the processes linked to teaching and learning in students recently graduated from the Faculty of Engineering at the Autonomous University of Baja California (Mexico). The perceptions of youth about the influence of processes directly related to their learning are gathered by using an online survey. The survey is evaluated by experts in academic areas and with experience implementing a quality system in the educational field. The sample consists of 82 participants at the end of the 2023-1 cycle. The results highlight a positive influence on student training and reveal areas for improvement to enrich future educational experience. It is concluded that this analysis allows identifying risks in quality management, opening the way to continuous improvement.

Resumen: Este estudio propone un modelo para evaluar el impacto de un sistema de gestión de calidad en los procesos vinculados con la enseñanza y el aprendizaje en estudiantes recién egresados de la Facultad de Ingeniería de la Universidad Autónoma de Baja California (México). Se recogen las percepciones de los jóvenes sobre la influencia de los procesos directamente relacionados con su aprendizaje utilizando una encuesta en línea. La encuesta es evaluada por expertos en áreas académicas y con experiencia en implementación de un sistema de calidad en el ámbito educativo. La muestra es de 82 participantes al final del ciclo 2023-1. Los resultados destacan una influencia positiva en la formación estudiantil y señalan áreas de mejora para enriquecer la experiencia educativa futura. Se concluye que este análisis permite identificar riesgos en la gestión de calidad, abriendo camino a la mejora continua.

SUMMARY: There exists a scarcity of neurocognitive research that has successfully used electrophysiology as an objective tool to assess different learning modalitiesthat are commonly used in anatomy. The objective of this study was to explore the trend in the expression of brain waves in medical students when using different didactic strategies in learning anatomy. An exploratory, observational, cross-sectional study was conducted on 22 first- semester medical students in anatomy. Using didactic strategies with different pedagogical tools such as biological models (human skulls and pig hearts) and/or digital application (Visible Body software), and different evaluation methods, students were grouped into three groups: "EOR1" students who learned using a skull and were evaluated with it; "EOV1" students who learned using a pig heart and were evaluated with the Visible Body software; and "EOV2" for students who learned through the Visible Body software and were evaluated with it. During the evaluation, each student was monitored in real-time using an electroencephalogram and the Emotiv EPOC brain-computer interface system to record the electro-physiological activity of beta (B), theta (T), and gamma (G) waves. The data obtained (the trend of the electrical activity of each wave and its relationship with students' performance in each didactic strategy) were analyzed using Pearson's correlation coefficient. Groups EOR1 and EOV1 had satisfactory results in their evaluations and showed a predominance of B waves (x=67.33) and T waves (x=57.67). Additionally, a strongly positive correlation (r=0.82) was found between the presence of B waves and the duration of T waves. Students who used three-dimensional biological models as a pedagogical tool showed a predominance of B and T waves, which are associated with sensorimotor and exploratory learning necessary for studying anatomy.

RESUMEN: Son escasos los estudios de neurociencia cognitiva que permitan comprender, de manera objetiva, las manifestaciones electrofisiológicas de los estudiantes de medicina expuestos a diferentes herramientas pedagógicas utilizadas en el área de anatomía. El objetivo de este trabajo fue explorar la tendencia en la expresión de las ondas cerebrales de estudiantes de medicina, al utilizar diferentes estrategias didácticas en el aprendizaje de la anatomía. Se realizó un estudio exploratorio, observacional, de corte transversal en 22 estudiantes de medicina de primer semestre en anatomía. Utilizando estrategias didácticas con diferentes herramientas pedagógicas; como modelos biológicos (cráneos humanos y corazones porcinos) y/o aplicación digital (software Visible Body (SVB)), y diferente método de evaluación, se agruparon los estudiantes en tres grupos: “EOR1” estudiantes que aprendieron usando un cráneo y se evaluaron con este, “EOV1” estudiantes que aprendieron usando un corazón porcino y fueron evaluados con el SVB, y “EOV2” para los estudiantes que aprendieron a través del SVB y fueron evaluados con este. Durante la evaluación, cada estudiante fue monitorizado en tiempo real, utilizando un electroencefalograma y el sistema interfaz cerebro - computadora Emotiv EPOC para registrar la actividad electrofisiológica de las ondas beta (B), theta (T) y gamma (G). Los datos obtenidos (tendencia de la actividad eléctrica de cada onda y su relación con el desempeño de los estudiantes en cada estrategia didáctica) fueron analizados usando el índice de correlación de Pearson. Los grupos EOR1 y EOV1, tuvieron resultados satisfactorios en sus evaluaciones y presentaron predominio de ondas B (X=67,33) y T (X=57,67), además, se evidenció una correlación fuertemente positiva (r=0,82) entre la presencia de B y el tiempo de permanencia de T. Los estudiantes que utilizaron modelos biológicos tridimensionales como herramienta pedagógica presentaron predominio de las ondas B y T, asociadas con aprendizajes sensoriomotores y de tipo exploratorio necesarios para el estudio en anatomía.

Abstract Background Hidradenitis suppurativa (HS) is a chronic inflammatory disease that leads to the formation of nodules, abscesses and fistulas, with the formation of scars and fibrosis, causing significant impairment in patient quality of life. The diagnosis is clinical, using scores to classify the severity of the condition; currently the most recommended classification is the International Hidradenitis Suppurativa Severity Scoring System (IHS4). Doppler ultrasound has been used to complement the clinical evaluation of patients with HS. It is possible to observe subclinical lesions that change the staging, the severity of the case, and its treatment, either clinical or surgical. Correct treatment is essential to minimize the consequences of this disease for the patient. Objective To establish an outpatient protocol for the use of Doppler ultrasound in the care of patients with HS. Methods A narrative review of the literature was carried out on the use of Doppler ultrasound in patients with hidradenitis suppurativa; a referring protocol and technique orientations for imaging assessment in HS were created. Results Recommendation to perform ultrasound evaluation of symptomatic areas eight weeks after using antibiotics and four, 12, and 24 weeks after starting immunobiologicals; apply SOS-HS ultrasound severity classification. Study limitations The review did not cover all literature on ultrasound and HS; no systematic review was carried out, but rather a narrative one. Conclusions The correct assessment of patients staging must be carried out using dermatological ultrasound to avoid progression to scars and fibrosis, which compromise patients quality of life. (HS nodules fistulas fibrosis life condition IHS4. IHS4 IHS . (IHS4) case surgical created four 12 2 immunobiologicals SOSHS SOS one (IHS4 1 (IHS

This research presents the implementation and evaluation of machine learning models to predict solar irradiance (W/m²). The objective is to provide valuable insights for making informed decisions regarding solar system design and financing. A thorough exploratory data analysis was conducted on the Southern African Universities Radiometric Network (SAURAN) data collected at the University of Pretoria's station to gain insights into the patterns of solar irradiance over the past 10 years. Python's functions and libraries are utilized extensively for conducting exploratory data analysis, model implementation, model testing, forecasting, and data visualization. Random Forest (RF), k-Nearest Neighbors (KNN), Feedforward Neural Network (FFNN), Support Vector Regression (SVR), and extreme Gradient Boosting models (XGBoost) are implemented and evaluated. The KNN model was found to be superior achieving a relative Root Mean Squared Error (RMSE), relative Mean Absolute Error (MAE), and R-Squared (R²) of 5.77%, 4.51% and 0.89 respectively on testing data. The variable importance analysis revealed that temperature (°C) exerted the greatest influence on predicting solar irradiance, accounting for 44% of the predictive power. The KNN model is suitable to inform solar systems design and financing decisions. Directions for future studies are identified and suggestions for areas of exploration are provided to contribute to the advancement of solar irradiance predictions.