Abstract The olive leaf extract and olive leaf indicated a high potential for application in food additives and foodstuffs. It could be these bio-products useful and important in condition therapy related with oxidative stress and can use it to develop functional foods and to improve the food's shelf life. The olive leaf chemical composition of Oleaeuropaea L. grown from eljouf in Saudi Arabia, using solvents of increasing polarity cyclohexane, dichloromethane, chloroform, ethyl acetate, methanol and ethanol was determined using by GC/MS. Furthermore, the antioxidant activity (diphenylpicrylhydrazyl (DPPH), anti-aging, and anti-tuberculosis of olive leaf extracts were evaluated. The results indicated that extract of Oleaeuropaea L. has a considerable contains in polyphenols (hydroxytyrosol, oleuropein and their derivatives) regarding its antioxidant effects, the major components were detected by GC/MS in Olea dichloromethane extract are Hexadecanoic acid (15.82%), 7(4Dimethylaminophenyl)3,3,12trimethyl3,12dihydro6 Hpyrano[2,3c]acridin 6 one (11.21%), and in Olea chloroform extract are Hexatriacontane (12.68%), nTetratr iacontane (10.95%). The results concluded that the plant extract of chloroform showed no anti-aging activities and the lower anti-aging activities for cyclohexane extract, while, the Olea dichloromethane extract was the most active extract. The obtained data confirmed that the most active extract of anti-tubercolisis was for chloroform and ethyl acetate extract, while, anti-tubercolisis activity of ethanolic extract was the lower. The extract amount as well as the solvent polarity influence the inhibitory activity. A favorable connection was demonstrated inter alia the leaf extracts antioxidant activity and the content of total phenol. foodstuffs bioproducts bio products s life L Arabia GCMS GC MS Furthermore diphenylpicrylhydrazyl DPPH, DPPH , (DPPH) antiaging, antiaging anti aging, aging antituberculosis tuberculosis evaluated hydroxytyrosol, hydroxytyrosol (hydroxytyrosol derivatives effects 15.82%, 1582 15.82% 15 82 (15.82%) 74Dimethylaminophenyl3,3,12trimethyl3,12dihydro6 74Dimethylaminophenyl3312trimethyl312dihydro6 Dimethylaminophenyltrimethyldihydro 7 4Dimethylaminophenyl 3,3,12trimethyl3,12dihydro6 3 12trimethyl3 12dihydro6 Dimethylaminophenyl trimethyl dihydro 7(4Dimethylaminophenyl)3,3,12trimethyl3,12dihydro Hpyrano2,3cacridin Hpyrano23cacridin Hpyranocacridin Hpyrano 2,3c acridin 2 3c c 11.21%, 1121 11.21% 11 21 (11.21%) 12.68%, 1268 12.68% 12 68 (12.68%) 10.95%. 1095 10.95% . 10 95 (10.95%) while antitubercolisis tubercolisis phenol (DPPH 158 15.82 1 8 (15.82% 74Dimethylaminophenyl3 74Dimethylaminophenyl3,3,12trimethyl3,12dihydro 74Dimethylaminophenyl3312trimethyl312dihydro 3312trimethyl312dihydro6 trimethyldihydro 3,3,12trimethyl3,12dihydro 12trimethyl 12dihydro Hpyrano2 3cacridin cacridin 23c 112 11.21 (11.21% 126 12.68 (12.68% 109 10.95 9 (10.95% 15.8 (15.82 74Dimethylaminophenyl 3312trimethyl312dihydro 11.2 (11.21 12.6 (12.68 10.9 (10.95 15. (15.8 11. (11.2 12. (12.6 10. (10.9 (15. (11. (12. (10. (15 (11 (12 (10 (1 (
Resumo O extrato de folha de oliveira e a folha de oliveira indicaram alto potencial para aplicação em aditivos alimentares e alimentos. Esses bioprodutos podem ser úteis e importantes na terapia de condições relacionadas ao estresse oxidativo e podem ser utilizados para desenvolver alimentos funcionais e melhorar a vida útil dos alimentos. A composição química da folha de oliveira de Olea europaea L. cultivada em Eljouf na Arábia Saudita, usando solventes de polaridade crescente ciclohexano, diclorometano, acetato de etil clorofórmio, metanol e etanol foi determinada usando GC/MS. Além disso, foi avaliada a atividade antioxidante (difenilpicrilhidrazil - DPPH) antienvelhecimento e antituberculose de extratos de folha de oliveira. Os resultados indicaram que o extrato de Olea europaea L. que consideravelmente possui polifenois (hidroxitirosol, oleuropeína e seus derivados) quanto aos seus efeitos antioxidantes, os componentes majoritários detectados por GC/MS no extrato diclorometânico de Olea são o ácido hexadecanoico (15,82%), 7-(4-Dimetilaminofenil)-3,3,12-trimetil-3,12-dihidro-6H-pirano[2,3c]acridin-6-ona (11,21%) e no extrato de clorofórmio de Olea são Hexatriacontane (12,68%), nTetratr iacontane (10,95%). Os resultados concluíram que o extrato vegetal de clorofórmio não apresentou atividades antienvelhecimento e as atividades antienvelhecimento mais baixas para o extrato de cicloexanona, enquanto o extrato de Olea diclorometano foi o extrato mais ativo. Os dados obtidos confirmaram que o extrato mais ativo de antituberculose foi para clorofórmio e extrato de acetato de etila, enquanto a atividade antituberculose de extrato etanoico foi menor. A quantidade de extrato, bem como a polaridade do solvente influenciam a atividade inibitória, atividade e o teor de fenol total. L Saudita ciclohexano GCMS GC MS disso difenilpicrilhidrazil DPPH hidroxitirosol, hidroxitirosol (hidroxitirosol derivados antioxidantes 15,82%, 1582 15,82% , 15 82 (15,82%) 74Dimetilaminofenil3,3,12trimetil3,12dihidro6Hpirano2,3cacridin6ona 74Dimetilaminofenil3312trimetil312dihidro6Hpirano23cacridin6ona DimetilaminofeniltrimetildihidroHpiranocacridinona 7 4 Dimetilaminofenil 3,3,12 trimetil 3,12 dihidro 6H pirano 2,3c acridin 6 ona 3 12 2 3c H c 11,21% 1121 11 21 (11,21% 12,68%, 1268 12,68% 68 (12,68%) 10,95%. 1095 10,95% . 10 95 (10,95%) cicloexanona etila menor inibitória total 158 15,82 1 8 (15,82% 74Dimetilaminofenil3 12trimetil3 12dihidro6Hpirano2 3cacridin6ona Hpirano cacridin 3312 3,3,1 312 3,1 23c 11,21 112 (11,21 126 12,68 (12,68% 109 10,95 9 (10,95% 15,8 (15,82 74Dimetilaminofenil 12trimetil dihidroHpirano 12dihidro6Hpirano cacridinona 331 3,3, 31 3, 11,2 (11,2 12,6 (12,68 10,9 (10,95 15, (15,8 33 3,3 11, (11, 12, (12,6 10, (10,9 (15, (11 (12, (10, (15 (1 (12 (10 (