RESUMO Objetivo: Avaliar a funcionalidade e fatores associados em crianças e adolescentes com osteogênese imperfeita (OI). Métodos: Estudo transversal com 30 crianças e adolescentes com OI. Foram avaliados prontuários médicos, uso de bisfosfonatos, características socioeconômicas, dinamometria de preensão palmar, equilíbrio, hipermobilidade articular, nível de deambulação e escores do Pediatric Evaluation of Disability Inventory - Computer Adaptative Test (PEDI-CAT). Os dados foram apresentados em média e desvio padrão e comparados por teste t por Mann-Whitney, enquanto os categóricos foram apresentados em frequência e comparados pelo teste exato de Fisher. Análises intragrupos foram realizadas por análise de covariância (ANCOVA) ou Teste de Wilcoxon para postos sinalizados. O teste Tau-b de Kendall foi usado para correlações. Resultados: A idade variou de 6 a 18 anos. A amostra foi dividida em dois grupos de acordo com a gravidade da doença. Casos moderados/graves (n=10) apresentaram menor estatura e força muscular comparadas às dos leves (n=20). Fraqueza muscular foi observada em todos os casos de OI quando comparados à população normal. Não houve diferença nos domínios do PEDI-CAT com exceção do domínio mobilidade. Houve correlação entre o número de fraturas, tipo de OI, peso e equilíbrio e o domínio mobilidade; e entre os domínios Atividades Diárias e Mobilidade e Responsabilidade e Social/cognitivo do PEDI-CAT. Conclusões: Nossos achados sugerem que crianças com OI moderada/severa podem atingir o mesmo nível de funcionalidade que crianças com a forma leve. Fraturas podem ter grande influência no nível de funcionalidade e o tratamento deve enfocar a prevenção e a reabilitação desses eventos. Objetivo . (OI) Métodos 3 médicos bisfosfonatos socioeconômicas palmar articular PEDICAT. PEDICAT PEDI CAT (PEDI-CAT) MannWhitney, MannWhitney Mann Whitney, Whitney Mann-Whitney Fisher ANCOVA (ANCOVA sinalizados Taub Tau b correlações Resultados 1 anos doença moderadosgraves moderados graves n=10 n10 n 10 (n=10 n=20. n20 n=20 20 (n=20) normal mobilidade fraturas Socialcognitivo Social cognitivo CAT. Conclusões moderadasevera moderada severa leve eventos (OI (PEDI-CAT n=1 n1 (n=1 n2 n=2 2 (n=20 n= (n= (n=2 (n

ABSTRACT Objective: The aim of this study was to evaluate the functioning and associated factors in children and adolescents with osteogenesis imperfecta (OI). Methods: This is a cross-sectional study conducted on 30 children and adolescents with OI. Medical records, use of bisphosphonates, socioeconomic status, handgrip strength, balance, joint hypermobility, ambulatory level, and the Pediatric Evaluation of Disability Inventory—Computer Adaptative Test (PEDI-CAT) scores were assessed. Data is presented as mean and standard deviation and Student’s t-test or Mann–Whitney U test. Categorical data is presented as frequency and analyzed using Fisher’s exact test. Within-group analyses were conducted using ANCOVA or Wilcoxon signed-rank test. Correlations used Kendall’s Tau-b test. Results: The participants involved in this study were 6–18 years old. The sample was separated into two groups according to disease severity. The moderate/severe OI group (n=10) presented a lower height and muscular strength than the mild group (n=20). Muscle weakness was observed in all participants with OI when compared with the normal population. No differences were observed between the groups in the PEDI-CAT scores except for the mobility domain. There were correlations between the PEDI-CAT mobility domain and the number of fractures, OI type, weight, and balance; there was also a correlation between the PEDI-CAT daily activities, mobility, responsibility, and social/cognitive domains. Conclusions: The findings suggest that children with moderate/severe forms of OI can achieve the same function levels as children with mild OI. Fractures can have a major influence on the functional level, and treatment should focus on the prevention and rehabilitation of these events when they occur. Objective . (OI) Methods crosssectional cross sectional 3 records bisphosphonates status balance hypermobility level InventoryComputer Inventory Computer PEDICAT PEDI CAT (PEDI-CAT assessed Students Student s ttest t test MannWhitney Mann Whitney Fishers Fisher Withingroup Within signedrank signed rank Kendalls Kendall Taub Tau b Results 618 6 18 6–1 old severity moderatesevere moderate severe n=10 n10 n 10 (n=10 n=20. n20 n=20 20 (n=20) population fractures type weight activities responsibility socialcognitive social cognitive domains Conclusions occur (OI 61 1 6– n=1 n1 (n=1 n2 n=2 2 (n=20 n= (n= (n=2 (n

ABSTRACT The search for new technologies capable of providing benefits to healthy eating is a global goal. The consumption of foods rich in carotenoids can prevent serious health problems. Thus, the availability of foods high in carotenoids that are accessible to the majority of the population is essential. Lettuce (Lactuca sativa L.) is a suitable species for biofortification research based on genetic improvements. In this study, we aimed to select and obtain hybrid lettuce populations with high agronomic potential and biofortified carotenoid content. Ten lettuce lines registered in the “BG α Biofort” software were selected for hybridization. The crosses used to obtain the hybrids involved two strains rich in at least one of the pigments (chlorophyll and carotenoids), and 24 experimental hybrids were obtained. A total of 37 genotypes (strains, hybrids, and commercial cultivars) were evaluated using a randomized block design for agronomic variables and chlorophyll and carotenoid content. Hybrids 12 (UFU-189#3#4#1 × UFU MC BIOFORT 2) and 25 (UFU66#4#2 × UFU-189#3#4#1) had the potential to produce dual-purpose populations (yield and carotenoid biofortification). Hybrid 27 (UFU66#4#2 × UFU MC BIOFORT1) exhibited the best pigment balance. Thus, F2 hybrids 12, 25, and 27 should be obtained to produce new cultivars of biofortified red and green lettuce for curly, american, mini, and romaine lettuce segments. goal problems Thus essential Lactuca L. L improvements study content BG Biofort hybridization carotenoids, , carotenoids) 2 3 strains, (strains 1 UFU189#3#4#1 UFU189341 189#3#4#1 189 4 (UFU-189#3#4# UFU66#4#2 UFU6642 UFU66 (UFU66#4# UFU-189#3#4#1 dualpurpose dual purpose yield biofortification. . biofortification) BIOFORT1 balance F curly american mini segments UFU189 UFU189#3#4# UFU18934 189341 189#3#4# 18 (UFU-189#3#4 UFU66#4# UFU664 UFU6 (UFU66#4 UFU-189#3#4# UFU18 UFU189#3#4 UFU1893 18934 189#3#4 (UFU-189#3# UFU66#4 (UFU66# UFU-189#3#4 UFU1 UFU189#3# 1893 189#3# (UFU-189#3 UFU66# (UFU66 UFU-189#3# UFU189#3 189#3 (UFU-189# (UFU6 UFU-189#3 UFU189# 189# (UFU-189 (UFU UFU-189# (UFU-18 UFU-189 (UFU-1 UFU-18 (UFU- UFU-1 UFU-

RESUMO A busca por novas tecnologias capazes de proporcionar benefícios para uma alimentação saudável tem sido meta mundial. A presença de alimentos ricos em carotenoides pode ser fundamental para prevenir sérios problemas de saúde. Aliar alimentos com altos teores de carotenoides e acessíveis para a maior parte da população é fundamental. A alface (Lactuca sativa L.) se apresenta como uma espécie adequada para investir em pesquisas com biofortificação a partir de melhoramento genético. Assim, o objetivo com este estudo foi selecionar híbridos de alface visando à obtenção de populações com potencial agronômico e biofortificadas para carotenoides. Dez linhagens de alface cadastradas no Software “BG α Biofort” foram utilizadas nas hibridações. Os cruzamentos para obtenção dos híbridos foram planejados envolvendo duas linhagens ricas em pelo menos um dos pigmentos (clorofila e carotenoides) sendo obtidos 24 híbridos experimentais. Foram avaliados 37 genótipos (linhagens, híbridos e cultivares comercias) em delineamento em blocos casualizados quanto as variáveis agronômicas e teores de clorofila e carotenoides. Foi verificado que os híbridos 12 (UFU-189#3#4#1 × UFU MC BIOFORT 2) e 25 (UFU66#4#2 × UFU-189#3#4#1) possuem potencial para obtenção de populações de duplo propósito (produtividade e biofortificada para carotenoide). O híbrido 27 (UFU66#4#2 × UFU MC BIOFORT1) foi o que apresentou maior equilíbrio para pigmentos. Sugere-se a obtenção de populações F2 dos híbridos 12, 25 e 27 visando a obtenção de novas cultivares de alfaces biofortificadas vermelhas e verdes, para os segmentos de alface crespa, americana, mini e romana. mundial saúde Lactuca L. L genético Assim BG Biofort hibridações 2 experimentais 3 linhagens, (linhagens comercias 1 UFU189#3#4#1 UFU189341 189#3#4#1 189 4 (UFU-189#3#4# UFU66#4#2 UFU6642 UFU66 (UFU66#4# UFU-189#3#4#1 produtividade carotenoide. carotenoide . carotenoide) BIOFORT1 Sugerese Sugere F verdes crespa americana romana UFU189 UFU189#3#4# UFU18934 189341 189#3#4# 18 (UFU-189#3#4 UFU66#4# UFU664 UFU6 (UFU66#4 UFU-189#3#4# UFU18 UFU189#3#4 UFU1893 18934 189#3#4 (UFU-189#3# UFU66#4 (UFU66# UFU-189#3#4 UFU1 UFU189#3# 1893 189#3# (UFU-189#3 UFU66# (UFU66 UFU-189#3# UFU189#3 189#3 (UFU-189# (UFU6 UFU-189#3 UFU189# 189# (UFU-189 (UFU UFU-189# (UFU-18 UFU-189 (UFU-1 UFU-18 (UFU- UFU-1 UFU-

RESUMEN En Paraguay en el periodo 2002 al 2022, los cambios en las familias se dieron por influencia de procesos de modernización y modernidad que se estudian teniendo como eje explicativo principal a los avances en la condición de la mujer, para los cuales también se analizan sus autonomías (económica, política y física). Se estudian: diversidad de tipos de los hogares, cre- cimiento de las uniones consensuales y crecimiento y bases de la jefatura femenina de hogar. Los datos del censo de 2002 y las encuestas de hogares del 2012 y 2022 del INE se compararon, porcentualmente. La orientación general es hacia la modernidad, pero no en las tres áreas; paralelamente se observa un aceleramiento de los procesos en el último decenio. Entre los tipos de hogares se halla el crecimiento del monoparental y el decrecimiento del extendido. La explosión de las uniones consensuales en la última década no necesariamente es modernidad; es un fenómeno tardío en la región. En 2022 ya se tiene un equilibrio entre uniones formales e informales. La creciente jefatura femenina de hogar es un indicador de modernidad; son casi 4 de cada 10 hogares familiares en 2022 habiendo crecido casi 2,5 veces en el lapso estudiado; inclusive en hogares nucleares completos. Para alcanzar esta condición política, las mujeres debieron integrarse al mercado de trabajo y lo hacen según su estado civil; por ejemplo, sepa- radas y divorciadas se ubican en el más alto nivel en ambos indicadores. Corresponde mayor estudio a las familias e incorporar a la agenda pública la diversidad familiar y sus cambios en curso para políticas públicas más precisas.

ABSTRACT In Paraguay (2002-2022), families undergone changes due to modernization and modernity processes that are studied based upon woman´s progress as main explanatory axis, and taking also in account her economic, political, and physical autonomies. Diversity of types of households, consensual unions growth, and feminine household headship, growth and its base are studied. INE´s census 2002 and 2012 and 2022 surveys data are compared (%). A general trend towards modernity is underway but it is not uniform within these three areas, and an acceleration pace during the last ten years is a parallel process. Within types of households, the one-parent and children household increase and the extended household decrease are noted. Consensual unions exploded during the last decade does not necessarily mean modernity; it is a late process in the region. By 2022, an equilibrium has arrived between formal and informal (consensual) unions. A growing feminine headship is a modernity sign, it has reached almost 4 out of every 10 households in 2022 and it has grown almost 2,5 times within 20 years, included two-parents and children family, ”the” model. For reaching this political level, wo- men should be within the labor market, and they do according to their civil-conjugal state; for instance, separated and divorced women are on the peak at both variables. Within the public agenda, more studies on families are required as well as to include families´ diversity and their ongoing changes for more precise public policies.

ABSTRACT "We are the trash, but the most important thing." The expression of a chambermaid sums up the fundamental tension of the so-called "care crisis", between the subordination of its protagonists due to the intersection of gender, class and foreign inequalities and the essential nature of this work for the sustain-ability of social life. This research adopts this perspective to offer proposals for improving the socio-legal methodology for analysing care-related rights. It does so based on the sector of chambermaids in tourist establishments in Spain and in particular through the experience of the Seville Union of Chambermaids (Kellys). Their experience allows us to reformulate the legal approach to their social rights. To this end, we present (1) the main violations of rights they identify; (2) the political-legal analysis these workers carry out on the inequalities that underlie these discriminations, as well as some reform proposals; and (3) the strategies for protection and self-protection of rights that they implement, both individually and collectively.

RESUMEN "Somos la basurilla, pero lo más importante." La expresión de una camarera de piso resume la tensión fundamental de la llamada "crisis de los cuidados", entre la subordinación de sus protagonistas por la intersección de las desigualdades de género, clase y extranjería y el carácter esencial de esa labor para la sostenibilidad de la vida social. Esta investigación adopta dicha perspectiva para ofrecer propuestas para mejorar la metodología socio-jurídica de análisis de los derechos relacionados con el cuidado. Lo hace a partir del sector de camareras de piso de establecimientos turísticos en España y en particular a través de la experiencia del Sindicato de Camareras de Piso (Kellys) de Sevilla. Su experiencia permite reformular el abordaje jurídico de sus derechos sociales. Para ello se exponen (1) las principales vulneraciones de derechos que identifican; (2) el análisis político-jurídico que las trabajadoras realizan sobre las desigualdades que subyacen a esas discriminaciones, así como algunas propuestas de reforma; y (3) las estrategias de tutela y autotutela de derechos que implementan, tanto individuales como colectivas.

ABSTRACT Nutritional assessment of mango trees based on diagnostic methods considering nutritional balance is recommended. This study aimed to establish optimum nutritional ranges using diagnostic methods, compare them, identify the most efficient diagnostic method, and select the nutrients responding best to the application of the diagnostic method. The study was conducted in commercial mango orchards in the São Francisco Valley. Nutritional content was calculated using the diagnosis and recommendation integrated system (DRIS-Beaufils, DRIS-Jones), modified DRIS (M-DRIS-Beaufils; M-DRIS-Jones), compositional nutrient diagnosis (CND), and mathematical chance (ChM) methods and compared using the chi-square test. Principal component analysis was applied to select the most efficient diagnostic method and the nutrients responsible for the greatest variability. The DRIS-Beaufils, M-DRIS-Beaufils, DRIS-Jones, M-DRIS-Jones, CND, and ChM methods generated nutritional sufficiency ranges for the evaluated cultivars. The nutritional diagnoses of the DRIS-Beaufils and M-DRIS-Beaufils methods were similar and discordant with those of DRIS-Jones, M-DRIS-Jones, and CND. The DRIS-Beaufils method, updated by Maia, proved to be more consistent for the nutritional assessment of mango trees. The nutrients N, P, K, Mg, and S in the Tommy Atkins cultivar; N, P, Mg, S, B, Mn, Zn, Mo, and Cl in the Kent cultivar; and N, P, K, Ca, S, B, Cu, Fe, Zn, Mo, and Cl in the Keitt cultivar showed significant responses to the application of the DRIS-Beaufils method updated by Maia. recommended them Valley DRISBeaufils, DRISBeaufils Beaufils, Beaufils (DRIS-Beaufils DRISJones, DRISJones Jones , DRIS-Jones) MDRISBeaufils M (M-DRIS-Beaufils MDRISJones, MDRISJones M-DRIS-Jones) CND (CND) (ChM chisquare chi square test variability MDRISBeaufils, Jones, DRIS-Jones M-DRIS-Jones cultivars Maia N P K Mg B Mn Zn Mo Ca Cu Fe (CND

RESUMO A avaliação nutricional em mangueiras baseada em métodos diagnósticos que consideram o equilíbrio nutricional tem sido recomendada. Os objetivos deste estudo foram: estabelecer faixas nutricionais ótimas por métodos diagnósticos e compará-las entre si; identificar o método diagnóstico mais eficiente na determinação de desequilíbrios nutricionais; e selecionar os nutrientes que melhor respondem à aplicação do método diagnóstico. O estudo foi realizado em pomares comerciais de mangueira no Vale do São Francisco-PE, Brasil. Foram calculados os teores nutricionais pelos métodos Sistema Integrado de Diagnóstico e Recomendação (DRIS-Beaufils, DRIS-Jones), DRIS Modificado (M-DRIS-Beaufils; M-DRIS-Jones), Diagnose da Composicão Nutricional (CND) e Chance Matemática (ChM) e comparados entre si pelo teste qui-quadrado. A análise de componentes principais foi aplicada para selecionar o método diagnóstico mais eficiente e os nutrientes responsáveis pela maior variabilidade. Os métodos DRIS Beaufils, M-DRIS Beaufils, DRIS Jones, M-DRIS Jones, CND e ChM geraram faixas de suficiência nutricional para as cultivares avaliadas. Os diagnósticos nutricionais dos métodos DRIS-Beaufils e M-DRIS Beaufius foram semelhantes entre si e discordantes dos métodos DRIS-Jones, M-DRIS-Jones e CND que foram semelhantes. O método DRIS Beaufils atualizado por Maia mostrou-se mais consistente na avaliação nutricional de mangueiras. Os nutrientes N, P, K, Mg e S na cultivar Tommy Atkins; N, P, Mg, S, B, Mn, Zn, Mo e Cl na cultivar Kent; e N, P, K, Ca, S, B, Cu, Fe, Zn, Mo e Cl na cultivar Keitt apresentam potencial de resposta significativa à aplicação do método DRIS-Beaufils atualizado por Maia. recomendada comparálas compará las FranciscoPE, FranciscoPE Francisco PE, PE Francisco-PE Brasil DRISBeaufils, DRISBeaufils (DRIS-Beaufils DRISJones, DRISJones Jones , DRIS-Jones) MDRISBeaufils M (M-DRIS-Beaufils MDRISJones, MDRISJones M-DRIS-Jones) (CND (ChM quiquadrado. quiquadrado qui quadrado. quadrado qui-quadrado variabilidade MDRIS avaliadas DRIS-Jones mostrouse mostrou se N P K Atkins B Mn Zn Kent Ca Cu Fe

Abstract Introduction: a blood transfusion is a therapeutic procedure that involves the administration of blood or its derivatives, in order to correct hematological disorders, restore hemodynamic balance or improve tissue oxygenation. It is carried out under strict protocols in order to minimize the risks of adverse transfusion reactions, considered as an unwanted and unexpected response associated with blood transfusion. Methods: descriptive study of 13,925 patients in which 67 people presented a transfusion reaction between the years 2020 to 2022. A secondary source of information was used from which the demographic and clinical variables and patients reported with transfusion reactions were taken. The information was analyzed with absolute and relative frequencies and their 95% confidence interval. Results: during 2020-2022, 67 adverse reactions related to the transfusion of 53,418 blood components were reported. Allergic reactions were the most common 85.07% (95% CI 74.26-92.60). Regarding the severity of the reaction, most people had a mild reaction 63.64% (2020), 81.50% (2021), 79.30% (2022). The prevalence for the female sex was higher 63.64%, 59.3% and 62.1% and for the age of people between 18 to 59 years old 54.55%, 44.44% and 37.9% respectively. Conclusion: blood transfusion plays a crucial role in various clinical contexts. Worldwide, adverse events affect between 1% and 3% of transfused patients. In Colombia, they affect 0.12%, the same as in this study where 0.12% presented an adverse transfusion reaction. This shows an under-registration at the national level, raising questions about their quality and timeliness.

Resumen Introducción: una transfusión de sangre o sus componentes, con el fin de corregir trastornos hematológicos, restaurar el equilibrio hemodinámico o mejorar la oxigenación tisular se lleva a cabo bajo estrictos protocolos con el fin de minimizar los riegos de las reacciones adversas transfusionales, consideradas como una respuesta indeseada e imprevista asociada a la transfusión sanguínea. Métodos: estudio descriptivo de 13925 pacientes en el que 67 personas presentaron alguna reacción transfusional entre los años 2020 a 2022. Se utilizó una fuente de información secundaria de la cual se tomaron las variables demográficas, clínicas, pacientes reportados con reacciones transfusionales. La información se analizó con frecuencias absolutas, relativas y su intervalo de confianza del 95%. Resultados: durante el 2020-2022 se reportaron 67 reacciones adversas relacionadas con la transfusión de 53.418 hemocomponentes. Las reacciones alérgicas fueron las más comunes 85.07% (IC 95% 74.26-92.60). En cuanto a la severidad de la reacción la mayoría de las personas presentó reacción leve 63.64% (2020), 81.50% (2021), 79.30% (2022). La prevalencia para el sexo femenino fue mayor 63.64%, 59.3% y 62.1% y para la edad las personas entre 18 a 59 años 54.55%, 44.44% y 37,9% respectivamente. Conclusión: la transfusión sanguínea desempeña un papel crucial en diversos contextos clínicos. A nivel mundial, los eventos adversos afectan entre el 1% y el 3% de los pacientes transfundidos, en Colombia, afecta al 0,12%, igual que en este estudio donde el 0,12 % presentó reacción adversa transfusional. Lo que evidencia un subregistro a nivel nacional planteando interrogantes sobre la calidad y oportunidad de éstos.

Abstract Violence against indigenous peoples has notably increased in recent years, and its news has been consequent on the violence faced by defenders of their rights. This article aims to explain this pattern of violence, demonstrating how legal uncertainty within the demarcation process encourages indigenous people and landowners to go to war. Through the study of the case of the Xukuru People of Ororubá, we describe two major violent events to demonstrate the set of threats, murders, autonomous retaking of demarcated territory, and institutional violence incidents by the police, Federal Public Prosecutor's Office and FUNAI. We rationalize these facts in a game theory matrix to demonstrate that the legal insecurity of the territory under demarcation leads both sides, as rational actors, to act and use all available resources to defeat the opponent, generating a suboptimal balance. This result leads to two outspreads. First, Brazil's failure to comply with the obligation to provide domestic legal effects allows the courts to adopt a legal thesis that conditions the effectiveness of territorial rights to Funai's budget. Second, an informal institutional arrangement translated into the permanence of the territory with non-indigenous people's rule. It was identified by the set of sanctions that the literature called the enemy's logic, composed of the criminalization of indigenous leaders and human rights defenders, as well as the distortion of purpose in the performance of public bodies. Therefore, this work contributes to the literature of Indigenous Law, Constitutional Law, and International Human Rights Law by offering a causal link between state omission and physical and institutional violence. years war Ororubá threats murders police Prosecutors Prosecutor s FUNAI sides actors opponent balance outspreads First Brazils Brazil Funais Funai budget Second nonindigenous non rule enemys enemy logic bodies Therefore

Resumo A violência contra povos indígenas e seus membros aumentou de maneira notável nos últimos anos, cujas notícias têm sido acompanhadas pela violência enfrentada por defensores de seus direitos. O objetivo deste artigo é oferecer uma explicação para este padrão de violência, demonstrando como a insegurança jurídica dentro do processo demarcatório incentiva povos indígenas e proprietários a entrar em guerra. Através do estudo do caso do Povo Xukuru do Ororubá, descrevemos dois grandes eventos de violência enfrentados para demonstrar o conjunto de ameaças, assassinatos, retomadas autônomas de território demarcado e violência institucional exercida pelas polícias, Ministério Público Federal e Funai. Racionalizamos esses fatos numa matriz de teoria dos jogos para demonstrar que a indefinição da situação do território em demarcação leva ambos os lados, como atores racionais, a agir ao invés de se omitir, utilizando todos os recursos disponíveis para derrotar o oponente e gerando um equilíbrio subótimo. Este resultado leva a dois grandes desdobramentos. Primeiro, o descumprimento pelo Brasil da obrigação de prover dispositivos de direito interno a permitir com que os tribunais adotem tese jurídica que condiciona a eficácia dos direitos territoriais ao orçamento da Funai. Segundo, a existência de um arranjo institucional informal traduzido na permanência do território com os não-indígenas e identificado pela existência de sanções que a literatura denomina como lógica do inimigo, composta pela criminalização de lideranças indígenas e defensores de direitos humanos, assim como pelo desvirtuamento de finalidade na atuação de órgãos públicos. Desta feita, este trabalho contribui para a literatura do Direito Indigenista, Direito Constitucional e Direito Internacional dos Direitos Humanos ao oferecer um nexo de causalidade entre a omissão do estado e a violência física e institucional. anos guerra Ororubá ameaças assassinatos polícias Funai lados racionais omitir subótimo desdobramentos Primeiro Segundo nãoindígenas não inimigo humanos públicos feita Indigenista

Abstract The aim of this article is to apply the model of Thirlwall's simple rule to analyze the causes of the divergent equilibrium growth rates between China and Mexico. The Fully Modified OLS method by Peter C. B. Phillips and Bruce E. Hansen is used. This approach offers precise estimates for the long-term relationships between GDP and exports, addressing endogeneity and autocorrelation. Through this estimator, we obtained the equilibrium GDP growth rates and the income elasticities of import demand. It is recommended to implement industrial and trade policies in Mexico to boost its growth. A limitation is that a more detailed analysis of differentiated growth was not conducted, so it would be necessary to explore further the extended version of Thirlwall's Law. The originality of our work lies in contributing to the understanding of the disparities in economic growth between China and Mexico. In conclusion, we demonstrate the different growth capacities based on the constraints of each country's current accounts.

Resumen El objetivo de este artículo es aplicar el modelo de la regla simple de Thirlwall para analizar las causas de las tasas divergentes de crecimiento de equilibrio entre China y México. Se utiliza el método Fully Modified OLS de Peter C. B. Phillips y Bruce E. Hansen. Este enfoque ofrece estimaciones precisas para las relaciones de largo plazo entre el PIB y las exportaciones, abordando la endogeneidad y la autocorrelación. Mediante este estimador, obtuvimos las tasas de crecimiento de equilibrio del PIB y las elasticidades ingreso de la demanda de importaciones. Se recomienda implementar políticas industriales y comerciales en México para impulsar su crecimiento. Una limitante es que no se realizó un análisis más detallado del crecimiento diferenciado, por lo que habría que explorar más adelante la versión ampliada de Ley de Thirlwall. La originalidad de nuestro trabajo consiste en que contribuye a la comprensión de las disparidades de crecimiento económico entre China y México. En conclusión, evidenciamos las distintas capacidades de crecimiento en función de las restricciones de las cuentas corrientes de cada país.

Abstract The present paper empirically assesses the role of capital flows in the output dynamics of the Mexican economy over the period 1994-2023. We hypothesize that capital flows have helped sustain a long-term economic growth rate that exceeds what is warranted by Mexico’s current account equilibrium. Our main contribution is to furnish empirical evidence supporting the Thirlwall-Hussain (1982) hypothesis. That is, capital flows are needed to finance the current account gap of economies growing beyond their means. Our analysis represents the first empirical test ever of such a model for the case of Mexico. Furthermore, our estimates from a vector error-correction model show that capital flows (FDI), imports and exports are intimately linked. Moreover, exports and FDI together provide the foreign exchange used to cope with technological and capital goods dependence. We conclude that finance is the most salient variable of overall economic dependence along the global supply chains. The main limitation of our study is that further empirical comparative analysis is required before generalizations can be reasonably made, a task for future endeavors.

Resumen Este trabajo evalúa empíricamente el papel de los flujos de capital en el crecimiento económico de México durante el período 1994-2023. La hipótesis central es que los flujos de capital contribuyen a mantener un crecimiento de largo plazo mayor al que se justificaría con equilibrio en la cuenta corriente. La principal contribución es proveer evidencia consistente con la hipótesis Thirlwall-Hussain (1982). Es decir, se requieren entradas de capital para financiar los déficits en la cuenta corriente de las economías que crecen más allá de sus medios. Este estudio es pionero en contrastar este modelo para el caso de México. Nuestras estimaciones, con base en un modelo de corrección de errores, muestran que los flujos de capital, las exportaciones y las importaciones están estrechamente ligadas. Las exportaciones y la inversión extranjera directa proveen las divisas necesarias para enfrentar la dependencia de tecnología y bienes de capital. La conclusión es que el financiamiento es una variable clave de la dependencia a lo largo de las cadenas globales de valor. La principal limitación es que se requiere investigación adicional para generalizar nuestros resultados.

Abstract The aim of this paper is to examine the impact of the characteristics of specialization patterns on industrial dynamics, using a strong version of Thirlwall's external constraint model, for 13 manufacturing subsectors in Mexico during the period 1995-2020. The main findings show that: i) the growth of the manufacturing sector is constrained by the current account equilibrium; ii) the income elasticity of exports increases as productivity and capital accumulation grow; iii) the income elasticity of imports is greater to the extent that the participation of foreign value added in export production increases. With this evidence, it is possible to conclude that the deepening of the outward industrialization model has limited the gains associated with trade and slowed down economic growth. In this context, it is essential to operate an industrial policy that strengthens internal supply chains and the position within global value chains. The contribution of the work lies in analyzing at the subsector level the implications of the composition of trade on economic expansion.

Resumen El objetivo de esta investigación es examinar el impacto de las características de los patrones de especialización sobre la dinámica industrial, mediante una versión fuerte del modelo de restricción externa de Thirlwall, en 13 subsectores manufactureros de México durante el periodo 1995-2020. Los resultados principales muestran que: i) el crecimiento del sector manufacturero se encuentra restringido por el equilibrio de la cuenta corriente; ii) la elasticidad ingreso de las exportaciones aumenta en la medida que crece la productividad y la acumulación de capital; iii) la elasticidad ingreso de las importaciones es mayor en la medida que aumenta la participación del valor agregado extranjero en la producción de exportación. Con esta evidencia, es posible concluir que la profundización del modelo de industrialización hacia fuera ha limitado las ganancias asociadas al comercio y ralentizado el crecimiento económico. En este contexto, es fundamental operar una política industrial que fortalezca las cadenas de suministro interna y la posición dentro de las cadenas globales de valor. La contribución del trabajo reside en analizar a nivel de subsector las implicaciones de la composición del comercio sobre la expansión económica.

Abstract Introduction: Nurses' intervention in the process of parental grief within primary healthcare reflects a fundamental health need, supporting couples in the experience of transition following the death of a child. It is crucial to value the functional and emotional balance of the family, as well as the grieving experience and associated feelings. Goals: To map the scientific evidence on nursing interventions within primary healthcare aimed at couples grieving the death of a child. Methods: A Scoping Review conducted following the PRISMA-ScR methodology and PCC mnemonic: population, concept, and context. Searches were performed in PubMed, CINAHL Complete, B-On, Science Direct, and RCAAP databases. Studies published in Portuguese, Spanish, and English from 2018 to 2023 were included. Identified studies were organized using Rayyan®, and their relevance was analyzed by two independent reviewers. Out of 1021 available articles, seven were included in the review. Results: Four themes emerged from the analysis: grief manifestations (denial, anger, bargaining, depression, acceptance); attitudes and behaviors promoting adaptive grief (religion, rituals, end-of-life care at home, redefining life goals, time occupation, self-care); obstacles to adaptive grief (insufficient professional support and behaviors of others); and support networks for parental grief (formal and informal). Final considerations: The grief experiences of couples allowed mapping of Family Health Nursing interventions aimed at couples grieving the death of a child, highlighting their priority, as well as the need for professional training in this area.

Resumo Introdução: A intervenção dos enfermeiros no processo de luto parental, em cuidados de saúde primários, espelha uma necessidade de saúde basilar, assistindo na vivência de um processo de transição pelo casal. Torna-se crucial a valorização do equilíbrio funcional e emocional da família, bem como a experiência de luto e os sentimentos vivenciados. Objetivo: Mapear a evidência científica sobre as intervenções de enfermagem, em cuidados de saúde primários, dirigidas ao casal enlutado pela morte de um filho. Metodologia: Scoping Review realizada de acordo com a metodologia PRISMA-ScR e a mnemónica PCC: população, conceito e contexto. Pesquisa realizada nas bases de dados PubMed, CINAHL Complete, B-On, Science Direct e RCAAP. Estudos publicados em português, espanhol e inglês foram incluídos, com o limite temporal 2018-2023. Os estudos identificados foram organizados no Rayyan®, e a sua relevância, analisada por dois revisores independentes. Dos 1021 artigos disponíveis, sete foram incluídos na revisão. Resultados: Da análise emergiram quatro temas: manifestações de luto (negação, raiva, negociação, depressão, aceitação); atitudes e comportamentos promotores de luto adaptativo (religião, rituais, fim de vida no domicílio, redefinição de objetivos de vida, ocupação do tempo, autocuidado); obstáculos ao luto adaptativo (apoio dos profissionais insuficiente e comportamentos de outras pessoas) e redes de apoio no luto parental (formal e informal). Considerações finais: As experiências de luto vivenciadas pelo casal, permitiram mapear as intervenções de Enfermagem de Saúde Familiar dirigidas ao casal pela morte do filho, as quais emergem como prioritárias, bem como a formação profissional na área.

Resumen El retroceso de los glaciares es una realidad en toda la cordillera de los Andes, sobre todo en montañas de baja altitud. Uno de estos casos es la pérdida de la masa de hielo remanente en el Carihuairazo (Tungurahua, Ecuador), que en los últimos años ha experimentado un retroceso considerable. En esta investigación se intenta caracterizar el retroceso de este glaciar y su implicación en la comunidad más cercana (Cunucyacu) por medio de la aplicación de una metodología de múltiples fuentes que incluye la recopilación de aerofotografías del glaciar, datos de estaciones meteorológicas cercanas, uso de datos de reanálisis del clima global, entrevistas a miembros de la comunidad y a andinistas que trabajan y frecuentan la zona. Para caracterizar la evolución de la masa del glaciar aplicamos un modelo hidroglaciológico que usa como entrada datos de series meteorológicas y cuyos parámetros fueron calibrados con el registro fotográfico del contorno del glaciar. Como resultados se puede evidenciar una pérdida del glaciar para el 2021 equivalente al 99% de su superficie en 1956 (0.34 km 2). El modelo logra simular la variación del área del glaciar durante 67 años, en donde se observa un decrecimiento continuo del glaciar a partir de 1978, con cortos periodos de recuperación y equilibrio, en donde la temperatura es la variable que mejor explica el retroceso del glaciar. El modelo no logra considerar el efecto de factores externos como el caso de la erupción del volcán Tungurahua que podría favorecer el retroceso del glaciar. El glaciar Carihuairazo se encuentra en una situación de inevitable desaparición y revela las vulnerabilidades de las comunidades que se enfrentan a este fenómeno como consecuencia del cambio climático.

Abstract The retreat of glaciers is a reality throughout the Andes Mountain range, especially in low-altitude mountains. One of these cases is the loss of the remaining ice mass in Carihuairazo (Tungurahua, Ecuador), which in recent years has experienced a considerable retreat. This research aims to characterize the retreat of this glacier and its implications for the nearby community (Cunucyacu) through the application of a multi-source methodology, which includes the collection of glacier aerial photographs, data from nearby meteorological stations, the use of global climate reanalysis data, interviews with community members, and mountaineers who work and frequent the area. To characterize the glacier’s mass evolution, a hydroglaciological model was applied, using input data from meteorological series, and its parameters were calibrated with the photographic record of the glacier’s outline. The results show a glacier loss of 99% of its surface in 1956 (0.34 km 2) by 2021. The model successfully simulates the glacier area variation over 67 years, revealing a continuous decrease since 1978, with short periods of recovery and equilibrium, where temperature is the variable that best explains the glacier’s retreat. However, the model fails to consider the effect of external factors, such as the eruption of the Tungurahua volcano that could enhance the glacier retreat. The Carihuairazo glacier is in a situation of inevitable disappearance, highlighting the vulnerabilities of communities facing this phenomenon as a consequence of climate change.

The Cuban industry La Purísima produces sauces and dressings for the national gastronomy; but it does not have a process for the deposition of chicken eggshells, as a result, 220 kg of eggshells are dumped daily, which generate a negative impact on the environment. The research evaluates the drying of hen eggshells with protein membrane on a laboratory scale, with a view to revalorizing this waste in the production of a calcium-rich poultry feed supplement. The calcium carbonate content of the shell was determined to confirm the potential application of the residue. The drying curve and drying rate curve was obtained by experimental measurement in a drying oven under aeration at 90 °C. The calcium carbonate content of the residue was 93,33 %. The drying curve was fitted to an exponential mathematical model as a function of the drying constant and the moisture in equilibrium at a temperature of 90 °C. The drying regime of the solid presented a period of decreasing drying rate up to a moisture value of 0,021 kg of water / kg of dry solid, for lower values, this presented a deviation from the exponential function in its rate. The utilization of residual eggshells proved to be an attractive source of calcium carbonate with potential for its use in the production of feed supplement for poultry.

RESUMEN En la Industria cubana La Purísima se producen salsas y aderezos para la gastronomía nacional; pero no dispone de un proceso para la deposición de las cáscaras de huevo de gallina, como resultado, se vierten diariamente 220 kg de cáscaras que generan un impacto negativo en el medio ambiente. La investigación evalúa el secado de las cáscaras de huevo de gallina con membrana proteica a escala de laboratorio, con vistas a revalorizar este residuo en la producción de un suplemento alimenticio para aves de corral rico en calcio. Se determinó el contenido de carbonato de calcio en la cáscara para confirmar la aplicación potencial del residuo. La curva de secado y del régimen de secado se obtuvo por medición experimental en un secadero bajo aireación a 90 °C. El contenido de carbonato de calcio en el residual fue de 93,33 %. La curva de secado se ajustó a un modelo matemático exponencial en función de la constante de secado y la humedad en equilibrio a una temperatura de 90 °C. El régimen de secado del sólido presentó un período de velocidad de secado decreciente hasta un valor de humedad de 0,021 kg de agua / kg de sólido seco, para valores inferiores presentó una desviación de la función exponencial en su velocidad. El aprovechamiento de las cáscaras de huevo residuales resultó ser una fuente atractiva de carbonato de calcio con potencialidades para su utilización en la elaboración de suplemento alimenticio para aves de corral.

Resumen El trastorno depresivo mayor (TDM) ha ganado relevancia en los últimos años, ya que es una de las principales causas de discapacidad a nivel mundial y ejerce un impacto significativo en la vida diaria de quienes lo experimentan. La relación entre la disbiosis intestinal y el TDM ha surgido como un componente crucial en el ámbito de la salud mental. La microbiota intestinal, que abarca una amplia diversidad de microorganismos, establece una conexión bidireccional con el TDM a través del eje microbiota-intestino-cerebro, la neuroinflamación y alteración de la función cerebral. El presente trabajo tuvo como objetivo, analizar la relación entre los problemas de equilibrio de los microorganismos en el intestino (fenómeno conocido como “disbiosis”) y el TDM. Se adoptó un enfoque cualitativo que combinó análisis bibliográfico y descriptivo, priorizando fuentes primarias en psicología, neurociencia y microbiología. Se examinaron investigaciones en inglés y español desde 2019 hasta 2023 utilizando motores de búsqueda y bases de datos reconocidas. En este contexto, se observó que el uso de probióticos se ha vuelto cada vez más relevante como parte del tratamiento complementario para el TDM. Los probióticos, como Lactobacillus plantarum DP189 y la bacteria Roseburia intestinalis, ejercen un impacto positivo en la microbiota intestinal, integridad de la barrera hematoencefálica y producción de neurotransmisores. La revisión destaca el papel crucial de la microbiota intestinal en el TDM y la prometedora utilidad de los probióticos como tratamiento complementario. Esto sugiere nuevas perspectivas terapéuticas y subraya la importancia de futuras investigaciones para comprender mejor esta compleja interacción.

Abstract Major depressive disorder (MDD) has gained relevance in recent years, as it is one of the main causes of disability worldwide and has a significant impact on the daily lives of those who experience it. The relationship between gut dysbiosis and MDD has emerged as a crucial component in the field of mental health. The gut microbiota, which encompasses a wide diversity of microorganisms, establishes a bidirectional connection with MDD through the microbiota-gut-brain axis, neuroinflammation and alteration of brain function. The objective of this work was to analyze the relationship between problems with the balance of microorganisms in the intestine (a phenomenon known as “dysbiosis”) and MDD. A qualitative approach was adopted that combined bibliographic and descriptive analysis, prioritizing primary sources in psychology, neuroscience and microbiology. Research in English and Spanish from 2019 to 2023 was examined using recognized search engines and databases. In this context, it was observed that the use of probiotics has become increasingly relevant as part of complementary treatment for MDD. Probiotics, such as Lactobacillus plantarum DP189 and the bacteria Roseburia intestinalis, have a positive impact on the intestinal microbiota, blood-brain barrier integrity, and neurotransmitter production. The review highlights the crucial role of gut microbiota in MDD and the promising utility of probiotics as a complementary treatment. This suggests new therapeutic perspectives and underlines the importance of future research to better understand this complex interaction.

ABSTRACT Grains are hygroscopic materials and, during storage, they are subject to exchanging moisture with the environment according to temperature and relative air humidity, making it important to monitor these factors. Digital temperature and relative air humidity sensors appear as an alternative for monitoring the moisture of grain mass inside silos; they are simple to install and use. Digital sensors present outstanding precision in temperature measurements. The objective in this study was to assess the efficiency and applicability of intergranular relative air humidity sensors linked to digital temperature sensors in the thermometry system of silos storing soybeans. Two samples of soybeans were analyzed in the upper, middle and lower thirds of the silo, for grain mass temperature, intergranular relative air humidity, estimated equilibrium moisture content according to collected data, and moisture content of the sampled grains. Moisture contents obtained from sensor measurements using the hygroscopic equilibrium equation and determined using the oven method were compared. The equilibrium moisture content estimated by the data provided by the sensors did not differ by the Tukey test (p ≤ 0.05) from the moisture content determined by the oven method. Digital temperature and relative air humidity sensors have proven to be efficient, as they contribute to estimating the equilibrium moisture content with satisfactory precision. storage factors use upper silo grains compared p 0.05 005 0 05 efficient 0.0 00 0.

RESUMO Grãos são materiais higroscópicos, e em seu armazenamento estão sujeitos às trocas de vapor de água de acordo com a temperatura e umidade relativa do ar, sendo importante o monitoramento desses fatores. Os sensores digitais de temperatura e umidade relativa do ar surgem como alternativa para monitoramento da temperatura da massa de grãos no interior de silos, apresentando simplicidade de instalação e utilização. Sensores digitais apresentam destacada precisão nas medições de temperatura. O objetivo deste estudo foi verificar a eficiência e aplicabilidade de sensores de umidade relativa do ar intergranular atrelados a sensores digitais de temperatura no sistema de termometria de silos armazenando grãos de soja. Duas amostragens de grãos de soja no terço superior, médio e inferior do silo foram analisadas para a temperatura da massa de grãos, umidade relativa do ar intergranular, teor de água de equilíbrio estimado conforme dados coletados e teor de água dos grãos amostrados. Realizou-se a comparação do teor de água obtido a partir das medições dos sensores usando a equação do equilíbrio higroscópico e pela determinação através do método da estufa. O teor de água de equilíbrio estimado pelos dados fornecidos pelos sensores não diferenciou pelo teste de Tukey (p ≤ 0.05) do teor de água determinado pela estufa. Os sensores digitais de temperatura e umidade relativa do ar demonstraram-se eficientes, visto que contribuem para estimativa do teor de água de equilíbrio com precisão satisfatória. higroscópicos fatores utilização superior amostrados Realizouse Realizou se estufa p 0.05 005 0 05 demonstraramse demonstraram eficientes satisfatória 0.0 00 0.