ABSTRACT The search for new technologies capable of providing benefits to healthy eating is a global goal. The consumption of foods rich in carotenoids can prevent serious health problems. Thus, the availability of foods high in carotenoids that are accessible to the majority of the population is essential. Lettuce (Lactuca sativa L.) is a suitable species for biofortification research based on genetic improvements. In this study, we aimed to select and obtain hybrid lettuce populations with high agronomic potential and biofortified carotenoid content. Ten lettuce lines registered in the “BG α Biofort” software were selected for hybridization. The crosses used to obtain the hybrids involved two strains rich in at least one of the pigments (chlorophyll and carotenoids), and 24 experimental hybrids were obtained. A total of 37 genotypes (strains, hybrids, and commercial cultivars) were evaluated using a randomized block design for agronomic variables and chlorophyll and carotenoid content. Hybrids 12 (UFU-189#3#4#1 × UFU MC BIOFORT 2) and 25 (UFU66#4#2 × UFU-189#3#4#1) had the potential to produce dual-purpose populations (yield and carotenoid biofortification). Hybrid 27 (UFU66#4#2 × UFU MC BIOFORT1) exhibited the best pigment balance. Thus, F2 hybrids 12, 25, and 27 should be obtained to produce new cultivars of biofortified red and green lettuce for curly, american, mini, and romaine lettuce segments. goal problems Thus essential Lactuca L. L improvements study content BG Biofort hybridization carotenoids, , carotenoids) 2 3 strains, (strains 1 UFU189#3#4#1 UFU189341 189#3#4#1 189 4 (UFU-189#3#4# UFU66#4#2 UFU6642 UFU66 (UFU66#4# UFU-189#3#4#1 dualpurpose dual purpose yield biofortification. . biofortification) BIOFORT1 balance F curly american mini segments UFU189 UFU189#3#4# UFU18934 189341 189#3#4# 18 (UFU-189#3#4 UFU66#4# UFU664 UFU6 (UFU66#4 UFU-189#3#4# UFU18 UFU189#3#4 UFU1893 18934 189#3#4 (UFU-189#3# UFU66#4 (UFU66# UFU-189#3#4 UFU1 UFU189#3# 1893 189#3# (UFU-189#3 UFU66# (UFU66 UFU-189#3# UFU189#3 189#3 (UFU-189# (UFU6 UFU-189#3 UFU189# 189# (UFU-189 (UFU UFU-189# (UFU-18 UFU-189 (UFU-1 UFU-18 (UFU- UFU-1 UFU-

RESUMO A busca por novas tecnologias capazes de proporcionar benefícios para uma alimentação saudável tem sido meta mundial. A presença de alimentos ricos em carotenoides pode ser fundamental para prevenir sérios problemas de saúde. Aliar alimentos com altos teores de carotenoides e acessíveis para a maior parte da população é fundamental. A alface (Lactuca sativa L.) se apresenta como uma espécie adequada para investir em pesquisas com biofortificação a partir de melhoramento genético. Assim, o objetivo com este estudo foi selecionar híbridos de alface visando à obtenção de populações com potencial agronômico e biofortificadas para carotenoides. Dez linhagens de alface cadastradas no Software “BG α Biofort” foram utilizadas nas hibridações. Os cruzamentos para obtenção dos híbridos foram planejados envolvendo duas linhagens ricas em pelo menos um dos pigmentos (clorofila e carotenoides) sendo obtidos 24 híbridos experimentais. Foram avaliados 37 genótipos (linhagens, híbridos e cultivares comercias) em delineamento em blocos casualizados quanto as variáveis agronômicas e teores de clorofila e carotenoides. Foi verificado que os híbridos 12 (UFU-189#3#4#1 × UFU MC BIOFORT 2) e 25 (UFU66#4#2 × UFU-189#3#4#1) possuem potencial para obtenção de populações de duplo propósito (produtividade e biofortificada para carotenoide). O híbrido 27 (UFU66#4#2 × UFU MC BIOFORT1) foi o que apresentou maior equilíbrio para pigmentos. Sugere-se a obtenção de populações F2 dos híbridos 12, 25 e 27 visando a obtenção de novas cultivares de alfaces biofortificadas vermelhas e verdes, para os segmentos de alface crespa, americana, mini e romana. mundial saúde Lactuca L. L genético Assim BG Biofort hibridações 2 experimentais 3 linhagens, (linhagens comercias 1 UFU189#3#4#1 UFU189341 189#3#4#1 189 4 (UFU-189#3#4# UFU66#4#2 UFU6642 UFU66 (UFU66#4# UFU-189#3#4#1 produtividade carotenoide. carotenoide . carotenoide) BIOFORT1 Sugerese Sugere F verdes crespa americana romana UFU189 UFU189#3#4# UFU18934 189341 189#3#4# 18 (UFU-189#3#4 UFU66#4# UFU664 UFU6 (UFU66#4 UFU-189#3#4# UFU18 UFU189#3#4 UFU1893 18934 189#3#4 (UFU-189#3# UFU66#4 (UFU66# UFU-189#3#4 UFU1 UFU189#3# 1893 189#3# (UFU-189#3 UFU66# (UFU66 UFU-189#3# UFU189#3 189#3 (UFU-189# (UFU6 UFU-189#3 UFU189# 189# (UFU-189 (UFU UFU-189# (UFU-18 UFU-189 (UFU-1 UFU-18 (UFU- UFU-1 UFU-

Resumen A partir de un estudio sociodemográfico, se describe la disolución conyugal por divorcio y separación, en familias de la región fronteriza del norte de México. Se proporciona una visión general acerca del nivel de frecuencia de la inestabilidad conyugal a nivel regional y algunas de las diferencias entre las entidades federativas que la componen. Se utiliza la Encuesta Nacional de la Dinámica Demográfica (Enadid) de 2018 y otras fuentes de información secundaria. El análisis se basa en los indicadores obtenidos de las disoluciones de la primera unión conyugal de mujeres alguna vez unidas, mediante el uso de la técnica de tablas de vida y los modelos de regresión logística. Entre otros resultados, se encontró que la región norteña tiene uno de los niveles más altos de disolución conyugal en el país, pero con interesantes diferencias que destacan entre los estados del noroeste y el noreste, generando un patrón dual en la región.

Abstract This is a descriptive socio-demographic study of the marital dissolution by divorce and separation in the northern border region of Mexico. The objective is to provide a general view of the level of this type of dissolutions in the region and some of its differences among the federal entities that form it. For this purpose, we use information from the National Survey of the Demographic Dynamics 2018 (ENADID) and secondary sources of information. The analysis is based on the indicators about the dissolution of the first conjugal union of ever-married women that were calculated through the life table technique and logistic regression models. The results evidence that the northern region has one of the highest levels of marital dissolution in the country, but with interesting differences between the states located in the northwest and the northeast generating a dual pattern in the region.

Resumen El sistema de producción bovino de doble propósito es el más predominante en el trópico, caracterizado por un sistema de pastoreo extensivo de gramíneas nativas o introducidas con baja digestibilidad y altas concentraciones de carbohidratos estructurales, provocando con esto una baja eficiencia productiva de los sistemas, ante este escenario, es necesario buscar alternativas que mejoren la eficiencia productiva. El objetivo fue evaluar la fermentación anaeróbica y digestibilidad ruminal in vitro de la materia seca (DIVMS) de los ensilados de S. bicolor y C. cajan. En los tratamientos se utilizaron cuatro sustratos (sorgo, sorgo + C. cajan, C. cajan, sorgo + C. cajan + inoculante) y cuatro tiempos de fermentación anaeróbica (0, 30, 60 y 90 días), en un diseño completamente al azar con un arreglo factorial 4x4, con tres repeticiones. El promedio de MS, MO, PC, FDN y FDA fue 373.9±41.43; 960.58±7.59; 87.82±24.95; 588.73±51.17; 371.76±61.39 g kg-1 de MS. Para la DIVMS fue de 56.32±9.05%. Se encontró diferencias significativas (P<0.05) para los parámetros de fermentación y DIVMS. El volumen máximo de gas se presentó en los tratamientos que contenían únicamente sorgo y sorgo + C. cajan + inoculante. Las fracciones de rápida fermentación fueron mayores (P<0.05) en los tratamientos sorgo + C. cajan + inoculante. Las fracciones de fermentación media y lenta fueron mayores en sorgo y sorgo + C. cajan + inoculante. Se concluye que la planta de C. cajan sola o combinada presenta un efecto negativo en la DIVMS.

ABSTRACT The dual-purpose cattle production system is the most predominant in the tropics, characterized by an extensive grazing system of native or introduced grasses with low digestibility and high concentrations of structural carbohydrates, causing with this a low productive efficiency of the systems, in this scenario, it is necessary to look for alternatives that improve productive efficiency. The objective was to evaluate the anaerobic fermentation and rumen digestibility in vitro of dry matter (DIVDM) of silages of S. bicolor and C. cajan. Four substrates (sorghum, sorghum + C. cajan, sorghum + C. cajan + inoculant) and four anaerobic fermentation times (0, 30, 60 and 90 days) were used in the treatments, in a completely randomized design with a 4x4 factorial arrangement, with three replications. The average for DM, OM, CP, NDF and ADF was 373.9±41.43; 960.58±7.59; 87.82±24.95; 588.73±51.17; 371.76±61.39 g kg-1 DM. For DIVDM it was 56.32±9.05 %. Significant differences (P<0.05) were found for fermentation parameters and DIVDM. The maximum volume of gas was presented in treatments containing only sorghum and sorghum + C. cajan + inoculant. The fractions of rapid fermentation were higher (P<0.05) in the treatments sorghum + C. cajan + inoculant. The fractions of medium and slow fermentation were higher in sorghum and sorghum + C. cajan + inoculant. It is concluded that the C. cajan plant alone or combined has a negative effect on DIVDM.

Resumen (Objetivo) Aunque el uso de vídeos de aula no es un tópico novedoso en la formación inicial del profesorado de educación matemática infantil, todavía hay preguntas de investigación sin resolver asociadas, sobre todo, a criterios para seleccionar y analizar vídeos desde un enfoque didáctico y disciplinar. Desde esta perspectiva, la finalidad del artículo es diseñar y validar una rúbrica que sirva para este doble propósito. (Metodología) A partir de un paradigma de investigación cualitativo, se ha seguido un proceso 4x3, es decir, un método secuenciado en cuatro fases con tres pasos en cada una de ellas: 1) revisión, 2) creación, 3) contraste y evaluación, y 4) mejora. (Resultados) La versión definitiva de la rúbrica, denominada R4, consta de 28 ítems organizados en cuatro dimensiones: 1) rol docente, sobre la función que tiene cada docente en el aula; 2) respuesta del alumnado infantil en la tarea, sobre su actuación; 3) relaciones matemáticas, sobre el tipo de matemática; 4) recursos, sobre la gestión y uso de recursos-materiales humanos. Para cada dimensión se considera diversas subdimensiones, en total 16. (Conclusiones) Se concluye que la rúbrica R4 aborda aspectos fundamentales (rol docente, respuesta del alumnado infantil, relaciones matemáticas y recursos) en la labor docente de una maestra o maestro de educación infantil, lo cual permite analizar la práctica docente de un modo holístico y fundamentado.

Resumo (Objetivo) Embora o uso de vídeos em sala de aula não seja um tópico novo na formação inicial de professores de matemática da educação infantil, ainda há questões de pesquisa não resolvidas associadas, sobretudo, aos critérios de seleção e análise de vídeos a partir de uma abordagem didática e disciplinar. A partir dessa perspectiva, o objetivo do artigo é projetar e validar uma rubrica que atenda a essa dupla finalidade. (Metodologia) Com base em um paradigma de pesquisa qualitativa, foi seguido um processo 4x3, ou seja, um método sequenciado em quatro fases com três etapas em cada uma delas: 1) revisão, 2) criação, 3) contraste e avaliação, e 4) aprimoramento. (Resultados) A versão final da rubrica, denominada R4, consiste em 28 itens organizados em quatro dimensões: 1) papel do professor, sobre a função que cada professor tem na sala de aula; 2) resposta dos alunos à tarefa, sobre seu desempenho; 3) relações matemáticas, sobre o tipo de matemática; 4) recursos, sobre o gerenciamento e o uso de recursos humanosmateriais. Para cada dimensão são consideradas diversas subdimensões, totalizando 16. (Conclusões) Conclui-se que a rubrica R4 aborda os principais aspectos (função do professor, resposta dos alunos da educação infantil, recursos e relações matemáticas) no trabalho de ensino de um professor da educação infantil, o que permite uma análise holística e informada da prática de ensino.

Abstract (Objective) Although the use of classroom videos is not a new topic in the initial training of early childhood mathematics education teachers, there are still unresolved research questions associated, above all, with criteria for selecting and analyzing these videos from both a didactic and disciplinary approach. From this perspective, the purpose of this article is to design and validate a rubric that serves this dual purpose. (Methodology) Based on a qualitative research paradigm, a 4x3 process has been followed, that is, a method sequenced in four phases with three steps in each one of them: 1) Review; 2) Creation; 3) Contrast and Evaluation; and 4) Improvement. (Results) The final version of the rubric, called R4, consists of 28 items organized in four dimensions: 1) Teaching role, on the role of the teacher in the classroom; 2) Response of children in the task to his/her performance; 3) Mathematical relations, on the type of mathematics; 4) and Resources, on the management and use of human resources and materials. For each dimension, several subdimensions are considered, 16 in total. (Conclusions) It is concluded that the R4 rubric addresses fundamental aspects (Teaching role, Childrens’ response, Mathematical relations and Resources) in the teaching work of an early childhood education teacher, which allows analyzing the teaching practice in a holistic and justified way.

Resumo: Este artigo analisa as discussões sobre o modelo alemão de aprendizagem dupla durante o diálogo social tripartite realizadona Costa Rica entre 27 de fevereiro e 1º de setembro de 2017. Essa arena de diálogo, moderada pela Organização Internacional do Trabalho, contou com a participação de representantes de empresas, sindicatos e do governo. A análise se concentra nas representações sociais e nas referências intersubjetivas especificamente desenvolvidas por atores estatais e paraestatais sobre as características e os potenciais do modelo alemão de aprendizagem dupla para resolver determinados problemas sociais na Costa Rica. Para isso, foram realizadas entrevistas semiestruturadas com representantes do Estado que participaram do diálogo, bem como com representantes paraestatais que estiveram envolvidos nas discussões sobre o tema. Como resultado, uma das principais constatações é que, na dinâmica da cooperação política, o modelo alemão de aprendizagem dual é tratado como um produto de “exportação/importação” capaz de resolver problemas como o desemprego juvenil e a pobreza entre os jovens. A referência ao modelo alemão de melhores práticas e à Alemanha como tal é usada para limitar a participação adequada dos atores e a compreensão dos problemas sociais.

Resumen: Este artículo analiza las discusiones sobre el modelo alemán de aprendizaje dual durante el diálogo social tripartito celebrado en Costa Rica entre el 27 de febrero y el 1 de setiembre de 2017. A este escenario de diálogo, moderado por la Organización Internacional del Trabajo, asistieron representantes de empresas, sindi- catos y el gobierno. El análisis se centra en las representaciones sociales y referencias intersubjetivas elaboradas específicamente por actores estatales y paraestatales sobre las características y potencialidades del modelo alemán de aprendizaje dual para resolver determinados problemas sociales en Costa Rica. Para ello, se realizaron entrevistas semiestructuradas a representantes estatales que participaron en el diálogo, así como a representantes paraestatales que intervinieron en las discusiones sobre el tema. Como resultado, uno de los principales hallazgos es que, dentro de la dinámica de cooperación política, el modelo alemán de aprendizaje dual es tratado como un producto de “exportación/importación” capaz de resolver problemas como el desempleo juvenil y la pobreza entre los jóvenes. La referencia al modelo alemán de buenas prácticas y a Alemania como tal se utiliza para limitar la adecuada participación de los actores y la comprensión de los problemas sociales.

Abstract: This article analyzes the discussions on the German dual apprenticeship model during the tripartite social dialogue held in Costa Rica between February 27 and September 1, 2017. This dialogue arena, moderated by the International Labour Organization, was attended by representatives of companies, trade unions, and the government. The analysis focuses on the social representations and intersubjective references specifically developed by state and parastatal actors on the characteristics and potentials of the German dual apprenticeship model to solve certain social problems in Costa Rica. For this purpose, semi-structured interviews were conducted with state representatives who participated in the dialogue, as well as with parastatal representatives who were involved in the discussions on the topic. As a result, one of the main findings is that within the dynamics of political cooperation, the German dual apprenticeship model is treated as an “export/import” product capable of solving problems such as youth unemployment and poverty among young people. The reference to the German best practice model and to Germany as such is used to limit the adequate participation of actors and the understanding of social problems.

Abstract The purpose of this study was to examine the effect of different decontamination agents on the bond strength of saliva-contaminated CAD/CAM blocks and repair composite materials. Two hunderd eighty 3-mm-thick specimens were prepared from four different CAD/CAM materials: Katana Zirconia UTML disc, IPS e.max CAD block, Shofu block, and Vita Enamic block. Each material was divided into seven different subgroups (N=70). Group 1 had a clean surface. The other groups were comprised of the samples, which were contaminated with human saliva: group 2: negative control (non-cleaned); group 3: cleaned with water spray; group 4: cleaned with 70% ethanol; group 5: cleaned with Ivoclean; group 6: cleaned with Katana Cleaner; and group 7: cleaned with phosphoric acid. After the decontamination protocols, the resin composite cylinders were bonded to the CAD/CAM surfaces with a thin layer of dual-cured resin cement. The samples were stored for 24 hours at 37°C in distilled water. Then, they were subjected to a shear bond strength test (SBS). The values were recorded, and fracture types were evaluated using a microscope. Data were analyzed using two-way ANOVA and Tukey’s post-hoc test. Generally, all decontaminating agents improved the SBS of composites to Katana Zirconia UTML, IPS e.max, and Vita Enamic materials (p<0.05). However, for Shofu materials, group 6 samples exhibited significantly higher bond strength values as compared with group 2 samples (p=0.026). The highest SBS values were seen in the phosphoric acid-treated group in Katana zirconia materials (26.45 ± 9.38 MPa), whereas the lowest values were seen in group 2 samples in Shofu materials (13.17±3.40 MPa). Each decontaminant agent improved the bond strength of composites to the contaminated CAD/CAM materials. If saliva is not cleaned before adhesive procedure, SBS values may decrease. All decontamination agents can be used safely on zirconia, lithium-disilicate glass-ceramic, hybrid ceramic, and polymer-infiltrated ceramic surfaces.

Resumen El propósito de este estudio fue examinar el efecto de diferentes agentes descontaminantes sobre la fuerza de unión de bloques CAD/CAM contaminados con saliva y materiales compuestos de reparación. Se prepararon doscientas ochenta muestras de 3 mm de espesor a partir de cuatro materiales CAD/CAM diferentes: disco Katana Zirconia UTML, bloque IPS e.max CAD, bloque Shofu y bloque Vita Enamic. Cada material se dividió en siete subgrupos diferentes (N=70). El grupo 1 tenía una superficie limpia. Los otros grupos estaban compuestos por muestras que estaban contaminadas con saliva humana: grupo 2: control negativo (no limpio); grupo 3: limpiado con agua pulverizada; grupo 4: limpiado con etanol al 70%; grupo 5: limpiado con Ivoclean; grupo 6: limpiado con Katana Cleaner; y grupo 7: limpiado con ácido fosfórico. Después de los protocolos de descontaminación, los cilindros de composite de resina se adhirieron a las superficies CAD/CAM con una fina capa de cemento de resina de curado dual. Las muestras se almacenaron durante 24 horas a 37°C en agua destilada. Luego, fueron sometidos a una prueba de resistencia al corte (SBS). Se registraron los valores y se evaluaron los tipos de fracturas utilizando un microscopio. Los datos se analizaron mediante ANOVA de dos factores y la prueba post-hoc de Tukey. En general, todos los agentes descontaminantes mejoraron el SBS de los composites con los materiales Katana Zirconia UTML, IPS e.max y Vita Enamic (p<0,05). Sin embargo, para los materiales Shofu, las muestras del grupo 6 exhibieron valores de fuerza de unión significativamente más altos en comparación con las muestras del grupo 2 (p=0,026). Los valores más altos de SBS se observaron en el grupo tratado con ácido fosfórico en materiales de circonio Katana (26,45 ± 9,38 MPa), mientras que los valores más bajos se observaron en las muestras del grupo 2 en materiales Shofu (13,17 ± 3,40 MPa). Cada agente descontaminante mejoró la fuerza de unión de los composites a los materiales CAD/CAM contaminados. Si no se limpia la saliva antes del procedimiento adhesivo, los valores de SBS pueden disminuir. Todos los agentes descontaminantes se pueden utilizar de forma segura en superficies de circonio, cerámica de vidrio de disilicato de litio, cerámica híbrida y cerámica con infiltraciones de polímeros.

Abstract Contrast-enhanced digital mammography (CEDM) is an emerging tool that has been increasingly implemented. It appears as an alternative to magnetic resonance imaging (MRI), using intravenous contrast to explore tumor angiogenesis. It combines conventional mammography (Mx) with post-contrast dual energy subtraction technique, resulting in increased detection of breast cancer, in a short study time and at a low cost. It is a promising method in selected cases and easy to read, being useful mainly in patients with breast cancer to detect additional lesions and determine the tumor size, that helps surgical planning, as well as in the evaluation of post-neoadjuvant chemotherapy response in the follow-up of patients treated with surgery, to address inconclusive findings in screening mammogram, or as an alternative when MRI is contraindicated. The purpose of this article is to assess the usefulness of contrasted mammography in daily practice and to determine its main indications. We review with our own cases the applications and characteristics of this method.

Resumen La mamografía contrastada (CEDM, contrast-enhanced digital mammography) es una herramienta nueva que ha ido implementándose de forma creciente. Aparece como alternativa a la resonancia magnética (RM), y al igual que esta, tiene como principio el uso de contraste endovenoso para explorar la angiogénesis tumoral. Combina la imagen de mamografía convencional (Mx) con la técnica de sustracción con energía dual poscontraste, lo que resulta en un incremento en la detección de cáncer de mama, en un tiempo corto de estudio y a un bajo costo. Es un método prometedor en casos seleccionados y de fácil lectura, siendo útil principalmente en pacientes con diagnóstico de cáncer de mama para detectar lesiones adicionales y determinar el tamaño tumoral, ayudando en la planificación quirúrgica, así como también en la evaluación de la respuesta a la neoadyuvancia. También en el seguimiento de pacientes operadas, para caracterizar lesiones dudosas en Mx y ecografía, o como alternativa ante contraindicación de la RM. El objetivo de este trabajo es valorar la utilidad de la mamografía contrastada en la práctica diaria y determinar sus principales indicaciones. Repasamos con casos propios las utilidades y características del método.

Resumen El desempeño reproductivo es crucial para la rentabilidad de la producción doble propósito en la Amazonía Ecuatoriana. Evaluar tres protocolos para Inseminación Artificial a tiempo fijo (IATF) en vacas en lactancia de doble propósito. Vacas Pardo Suizo en lactancia (n=301) recibieron 2 mg de benzoato de estradiol (EB) y un dispositivo intravaginal con 0,5 g de progesterona (P4) el Día 0 y fueron asignadas aleatoriamente en tres grupos. Las vacas del grupo EB recibieron 500 μg de cloprostenol (PGF2α) y se les retiró el dispositivo el Día 7, y recibieron 1 mg de EB el Día 8. Las vacas del grupo ECP fueron tratadas como las del grupo EB, excepto que recibieron 0,5 mg de cipionato de estradiol (ECP) en el día del retiro del dispositivo (Día 7) en lugar de EB el Día 8. En las vacas del grupo J-Synch, el retiro del dispositivo y la administración de PGF2α se realizaron el Día 6. Todas las vacas fueron IATF el Día 9 y las del grupo J-Synch recibieron 100 μg de gonadorelina en ese momento. Aunque el diámetro del folículo dominante y del CL fueron mayores (P<0,05) en las vacas del grupo J-Synch, las tasas de preñez a la IATF no difirieron entre los grupos (EB: 51,0%, ECP: 53,0% y J-Synch: 59,4%). Los tres protocolos probados se pueden aplicar con éxito en vacas de doble propósito amamantando.

Abstract Reproductive performance is crucial for profitability of dual-purpose cow-calf production in the Ecuadorian Amazon. To evaluate three different fixed-time artificial insemination (FTAI) protocols in suckled, dual-purpose cows in the Ecuadorian Amazon. Lactating, Brown Swiss cows (n=301) received 2 mg estradiol benzoate (EB) and an intravaginal device containing 0.5 g of progesterone (P4) on Day 0. They were allocated randomly into the following three treatment groups: Cows in the EB group received 500 μg cloprostenol (PGF2α), and P4 devices were removed on Day 7, and 1 mg EB was administered on Day 8. Cows in the ECP group were treated as those in the EB group, except that they received 0.5 mg estradiol cypionate (ECP) at the time of P4 device removal on Day 7 instead of EB on Day 8. Cows in the J-Synch group had the P4 device removed and PGF2α administered on Day 6. All cows were FTAI on Day 9; cows in the J-Synch group also received 100 μg gonadorelin at that time. Although the diameter of the dominant follicle and the resulting CL were greater (P<0.05) in cows in the J-Synch group, pregnancies per AI did not differ (P>0.2) among groups (EB: 51.0%, ECP: 53.0% and J-Synch: 59.4%). The three protocols tested were applied successfully in suckled, dual-purpose cows with no differences in pregnancies per AI.

Abstract Purpose: This study analyzes the influence of diagnostic and interactive use of the performance measurement system (PMS) on job satisfaction and affective organizational commitment. Originality/value: The study provides empirical evidence that contributes to highlighting the contrasting findings in the literature on how the use of PMS influences job satisfaction and the affective organizational commitment of individuals. Design/methodology/approach: A survey was carried out with middlelevel managers of companies featured in the Best Companies to Work For ranking by the Você S/A magazine, where a sample of 167 valid responses was obtained. We applied the structural equation modeling to test the hypotheses. Findings: The results show a direct relationship between the interactive use of PMS and job satisfaction. They also indicate a direct connection between job satisfaction and affective organizational commitment. Furthermore, they show that diagnostic use directly impacts affective organizational commitment, while interactive use indirectly impacts affective organizational commitment by mediating job satisfaction. These results contribute to the literature by revealing that PMS’s diagnostic and interactive uses result in different psychological consequences, such as job satisfaction and affective organizational commitment. They also contribute by reinforcing the previous literature regarding the complementarity and interdependence of the dual role of the PMS in the organizational context since the interactive use provides a flexible basis for the performance of activities, and the diagnostic use requires alignment of individual behaviors with organizational standards. Purpose (PMS Originality/value Originalityvalue Originality value individuals Design/methodology/approach Designmethodologyapproach Design methodology approach SA S magazine 16 obtained hypotheses Findings Furthermore PMSs s consequences activities standards 1

RESUMO Objetivo: Este estudo analisa a influência dos usos diagnóstico e interativo do sistema de mensuração do desempenho (PMS) na satisfação no trabalho e no comprometimento organizacional afetivo. Originalidade/valor: O estudo traz evidências empíricas que contribuem para o deslinde dos achados contrastantes da literatura sobre como o uso do PMS influencia na satisfação no trabalho e no comprometimento organizacional afetivo de indivíduos. Design/metodologia/abordagem: Uma survey foi realizada com gestores de nível intermediário de empresas classificadas no ranking Melhores Empresas para Trabalhar da revista Você S/A, em que se obteve uma amostra de 167 respostas válidas. Para testar as hipóteses, aplicou-se a modelagem de equações estruturais. Resultados: Os resultados mostram relação direta entre o uso interativo do PMS e a satisfação no trabalho. Também apontam relação direta entre a satisfação no trabalho e o comprometimento organizacional afetivo. Ainda, evidenciam que o uso diagnóstico afeta diretamente o comprometimento organizacional afetivo, enquanto o uso interativo afeta indiretamente o comprometimento organizacional afetivo, pela mediação da satisfação no trabalho. Esses resultados revelam que os usos diagnóstico e interativo do PMS implicam diferentes consequências psicológicas, como satisfação no trabalho e comprometimento organizacional afetivo. Também reforçam a literatura prévia quanto à complementaridade e interdependência do duplo papel do PMS no contexto organizacional, visto que o uso interativo fornece uma base flexível para o desempenho das atividades e o uso diagnóstico impõe alinhamento dos comportamentos individuais aos padrões organizacionais. Objetivo (PMS Originalidade/valor Originalidadevalor Originalidade valor indivíduos Design/metodologia/abordagem Designmetodologiaabordagem Design metodologia abordagem SA S A S/A 16 válidas hipóteses aplicouse aplicou estruturais Resultados Ainda psicológicas organizacionais 1

ABSTRACT Purpose: To determine normal corneal tomographic parameters in children and adolescents without corneal disease or atopy diagnosis. Methods: This descriptive cross-sectional study evaluated patients aged 8-16 years who underwent a complete slit-lamp biomicroscopic examination and tomographic corneal evaluation by a dual Scheimpflug analyzer, excluding those with ocular disease (including allergic conjunctivitis) or a positive prick test for systemic atopies. Results: A total of 170 patients were evaluated, and 34 patients (68 eyes) were analyzed once the exclusion criteria were applied. The sample’s mean age was 10.76 ± 2.31 years; with 19 (55.9%) men and 15 (44.1%) women. The mean keratometry in the flat meridian (Kflat), steep meridian (Ksteep), and maximum (Kmax) were 42.37 ± 1.63D, 43.53 ± 1.65D, and 43.90 ± 1.73D, respectively. The mean values for corneal asphericity (ε2) and thinnest point were 0.28 ± 0.11 and 550.20 ± 37.90 μm, respectively. The inferior-superior asymmetry ratio (I-S) and coma were 0.74 ±0.59D and 0.28 ± 0.12D, respectively. Conclusion: The knowledge of normal corneal tomographic parameters and their variation in children and adolescents without corneal disease or atopy may be useful for diagnosing keratoconus and initiating early disease treatment. Purpose diagnosis Methods crosssectional cross sectional 816 8 16 8-1 slitlamp slit lamp analyzer including conjunctivitis atopies Results 17 3 68 (6 eyes applied samples sample s 1076 10 76 10.7 231 2 31 2.3 1 55.9% 559 55 9 (55.9% 44.1% 441 44 (44.1% women Kflat, Kflat , (Kflat) Ksteep, Ksteep (Ksteep) Kmax (Kmax 4237 42 37 42.3 163D D 63D 1.63D 4353 43 53 43.5 165D 65D 1.65D 4390 90 43.9 173D 73D 1.73D respectively ε2 ε (ε2 028 0 28 0.2 011 11 0.1 55020 550 20 550.2 3790 37.9 μm inferiorsuperior inferior superior IS I S (I-S 074 74 0.7 059D 59D 012D 12D 0.12D Conclusion treatment 81 8- 6 ( 107 7 10. 23 2. 55.9 5 (55.9 44.1 4 (44.1 (Kflat (Ksteep 423 42. 435 43. 439 (ε 02 0. 01 5502 550. 379 37. 07 55. (55. 44. (44. (55 (44 (5 (4

RESUMO Objetivo: Identificar parâmetros tomográficos de normalidade em córneas de crianças e adolescentes sem a presença de atopias sistêmicas e alergias oculares. Métodos: Este estudo descritivo transversal avaliou pacientes com idade entre 8 e 16 anos que foram submetidos a exame biomicroscópico completo por lâmpada de fenda e avaliação tomográfica da córnea por tomógrafo dual Scheimpflug, excluindo pacientes com doença ocular (incluindo conjuntivite alérgica) ou prick test positivo para atopias sistêmicas. Resultados: Cento e setenta pacientes foram avaliados e após cumpridos os critérios de exclusão, 34 (68 olhos) foram analisados. A média etária da amostra foi 10,76 ± 2,31 anos; 19 (55,9%) eram meninos e 15 (44,1%) meninas. A média da ceratometria em dioptrias (D) no meridiano mais plano (Kflat), mais curvo (Ksteep) e máxima (Kmax) foram 42,37 ± 1,63D, 43,53 ± 1,65D e 43,90 ± 1,73D, respectivamente. Os valores médios da asfericidade corneana (ε2) e do ponto mais fino da córnea foram 0,28 ± 0,11 e 550,20 ± 37,90 micras (μm). A assimetria corneana inferior-superior (I-S) e coma foi em média 0,74 ± 0,59D e 0,28 ± 0,12D, respectivamente. Conclusão: O conhecimento dos valores médios e sua variação de parâmetros tomográficos da córnea em crianças e adolescentes sem atopias sistêmicas ou alergias oculares pode ser útil para o diagnóstico precoce do ceratocone e o seu tratamento em estágio inicial. Objetivo Métodos 1 Scheimpflug incluindo alérgica Resultados exclusão 3 68 (6 olhos analisados 1076 10 76 10,7 231 2 31 2,3 55,9% 559 55 9 (55,9% 44,1% 441 44 (44,1% meninas D (D Kflat, Kflat , (Kflat) Ksteep (Ksteep Kmax (Kmax 4237 42 37 42,3 163D 63D 1,63D 4353 43 53 43,5 165D 65D 4390 90 43,9 173D 73D 1,73D respectivamente ε2 ε (ε2 028 0 28 0,2 011 11 0,1 55020 550 20 550,2 3790 37,9 μm. μm . (μm) inferiorsuperior inferior superior IS I S (I-S 074 74 0,7 059D 59D 012D 12D 0,12D Conclusão inicial 6 ( 107 7 10, 23 2, 55,9 5 (55,9 44,1 4 (44,1 (Kflat 423 42, 435 43, 439 (ε 02 0, 01 5502 550, 379 37, (μm 07 55, (55, 44, (44, (55 (44 (5 (4

Abstract The purpose of this study is to analyze the most suitable research designs and evaluation instruments for the analysis of training needs in dual training (DT) professionals, assessing the procedures and dimensions that are examined. The figure of the company tutors in DT is an agent key for the preparation of apprentices training in the workplace, which is why it is considered of great interest to determine their needs to improve their professional practice. The methodology used has been the systematic bibliographic review. Starting from the search with a Boolean operator, we obtained 2.470 open access records published. The exploration was limited to the period comprehended between 2011-2021, in six data bases, which contained full text, and peer-reviewed journals and PhD dissertations. Finally, 54 investigations were selected. The findings reflect that the needs studies mostly use mixed research designs in which they apply the combination of interviews (structured, semi structured, in- depth, in group and individual) and questionnaires (online and in-person) as the main instruments of data colleccion. The questionnaires are used, in the majority of cases, to reach as many people as possible in the shortest time and interviews to deepen the subject of study. Regarding the evaluable dimensions, these focus in the methodological and technological aspects, communications and psycho-social skills and development of the own profession. (DT professionals examined workplace practice review operator 2470 2 470 2.47 published 20112021, 20112021 2011 2021, 2021 2011-2021 bases text peerreviewed peer reviewed dissertations Finally 5 selected structured (structured depth individual online inperson person in-person colleccion cases aspects psychosocial psycho social profession 247 47 2.4 2011202 201 202 2011-202 24 4 2. 201120 20 2011-20 20112 2011-2 2011-

Resumen El propósito de este estudio es analizar los diseños de investigación y los instrumentos de evaluación más adecuados para el análisis de necesidades formativas en profesionales de la formación dual (FD), valorando los procedimientos y dimensiones que se examinan. La figura de los tutores de empresa en la FD supone una función clave para la preparación de los aprendices en el puesto de trabajo, es por ello que se considera de gran interés determinar sus necesidades para mejorar su ejercicio profesional. La metodología empleada ha sido la revisión bibliográfica sistemática. Partiendo de la búsqueda con operador boleano, obtuvimos 2.470 registros publicados en abierto. Se limitó la exploración al período comprendido entre 2011-2021, en seis bases de datos, que contenían texto completo, en lengua inglesa o castellana, y artículos de revistas arbitradas y tesis doctorales. Finalmente se seleccionaron 54 investigaciones. Los hallazgos reflejan que los estudios de necesidades emplean, en su mayoría, diseños de investigación mixtos en los que aplican la combinación de las entrevistas (estructuradas, semiestructuradas, en profundidad, en grupo e individual) y los cuestionarios (en línea o presenciales) como principales instrumentos de recogida de información. Se emplean los cuestionarios en la mayoría de los casos para llegar al mayor número de personas en el menor tiempo posible y las entrevistas para profundizar en la materia de estudio. Respecto a las dimensiones evaluables estas se centran en aspectos metodológicos, tecnológicos, habilidades comunicativas y psicosociales y en el desarrollo de la propia profesión. FD, , (FD) examinan trabajo profesional sistemática boleano 2470 2 470 2.47 abierto 20112021, 20112021 2011 2021, 2021 2011-2021 datos completo castellana doctorales 5 investigaciones estructuradas, estructuradas (estructuradas semiestructuradas profundidad individual presenciales información metodológicos tecnológicos profesión (FD 247 47 2.4 2011202 201 202 2011-202 24 4 2. 201120 20 2011-20 20112 2011-2 2011-

A new composite material with magnetic and pH-responsive properties, composed of chitosan/poly(2-diisopropylamino)ethyl methacrylate (Fe3O4/SiO2/CS/PDPA) was developed with the purpose of removing avermectins in aqueous media. The material was characterized by different techniques to evaluate its characteristics. The adsorption process was investigated through the optimization of some parameters, with the most favorable results at pH 8.0, using 20 mg of adsorbent and stirring for 5 min. Under such conditions, the material showed adsorption efficiency of around 80.5, 69.9, and 74.8% for eprinomectin, doramectin and ivermectin, respectively. The adsorption mechanism was investigated using the pseudo-second order kinetic model and the Langmuir-Freundlich dual site isotherm model. Thermodynamic analysis indicated that the adsorption process is exothermic and spontaneous. The material also showed good regenerative capacity, allowing several reuse cycles. The results obtained suggest that the synthesized material has potential application as an adsorbent in the removal of avermectins from aqueous samples. pHresponsive responsive properties chitosan/poly2diisopropylaminoethyl chitosanpoly2diisopropylaminoethyl chitosanpolydiisopropylaminoethyl chitosan/poly 2 diisopropylamino ethyl chitosan poly Fe3O4/SiO2/CS/PDPA Fe3O4SiO2CSPDPA FeOSiOCSPDPA Fe3O4 SiO2 CS PDPA Fe O SiO (Fe3O4/SiO2/CS/PDPA media characteristics parameters 80 8 0 8.0 min conditions 805 80.5 699 69 9 69.9 748 74 74.8 eprinomectin ivermectin respectively pseudosecond pseudo second LangmuirFreundlich Langmuir Freundlich spontaneous capacity cycles samples poly2diisopropylaminoethyl diisopropylaminoethyl chitosanpoly CSPDPA FeO Fe3O 8. 80. 6 69. 7 74. polydiisopropylaminoethyl

Abstract We aimed to estimate genetic parameters and select sorghum lines for forage purposes based on agronomic and chemical traits. A total of 100 inbred lines, comprising the biomass/bmr, biomass, dual purpose (sweet/forage), and forage types, were evaluated in the 2020/2021 and 2021/2022 crop years. We analyzed the data using a linear mixed model approach. Genetic variance, line mean-based heritability, selection accuracy, genetic correlation between traits and crops and the coefficient of experimental variation were estimated. The breeding values of the lines were predicted, and the factor analysis and genotype-ideotype distance index based on BLUP (FAI-BLUP) were applied for multi-trait selection. Biomass production and cell wall composition traits were measured. There was genetic variation among the lines, with moderate to high heritability. The lines selected by the FAI-BLUP index resulted in significant genetic gains expected with selection for all traits. 10 biomassbmr biomass bmr biomass/bmr sweet/forage, sweetforage sweet/forage , sweet (sweet/forage) types 20202021 2020 2021 2020/202 20212022 2022 2021/202 years approach variance meanbased mean heritability accuracy estimated predicted genotypeideotype genotype ideotype FAIBLUP FAI (FAI-BLUP multitrait multi trait measured 1 (sweet/forage 2020202 202 2020/20 2021202 2021/20 202020 20 2020/2 202120 2021/2 20202 2 2020/ 20212 2021/

ABSTRACT Purpose: To describe an experimental surgical model in rats using a dual-plane technique for evaluation of biomaterials in an in-vivo silicone implant coverage. Methods: This study was developed following the ISO 10993-6 standard. In this study, 40 male Wistar rats weighing between 250 and 350 g were used, distributed into two groups: experimental, biomaterial superimposed on the minimammary prosthesis (MP); and control, MP without implantation of the biomaterial, with eight animals at each biological point: 1, 2, 4, 12, and 26 weeks. Thus, at the end of biological points (1, 2, 4, 12, and 26 weeks; n = 8 animals per week), the tissue specimens achieved were fixed in buffered formalin and stained with hematoxylin-eosin. Results: Macroscopically, throughout the study, no postoperative complications were apparent. In the histological analysis, it was possible to observe the evolution of the inflammatory response, tissue repair, and fibrous capsule during the biological points. Conclusions: The experimental model described in this study proved to be suitable for evaluating the biomaterial used in the coverage of breast silicone implants. Purpose dualplane dual plane invivo vivo Methods 109936 10993 6 10993- standard 4 25 35 groups (MP) control point 1 2 12 weeks Thus (1 week, week , week) hematoxylineosin. hematoxylineosin hematoxylin eosin. eosin hematoxylin-eosin Results Macroscopically apparent analysis response repair Conclusions implants 1099 3 (MP ( 109 10

BACKGROUND: This research explored how classroom plays could serve as pedagogical tools to introduce children to Sesotho and isiZulu vocabulary of artificial intelligence (AI). The article captures how student teachers learned to write plays that they could produce when they become professional teachers OBJECTIVES: The purpose of this study was to explore how student teachers engaged in a playwriting process, creating drama texts for early grades primary school learners about AI METHOD: The qualitative study employed, a participatory action research design. Data were collected through semi-structured interviews with the student teachers, coupled with a dual analysis of their drama texts. An inductive thematic analysis approach was applied for the data from interviews with the students. A deductive approach was implemented to analyse the drama texts according to criteria for playwriting with a pedagogical purpose RESULTS: The findings revealed that playwriting as a tool for pedagogy can be useful in developing student teachers' vocabulary of AI in Sesotho or isiZulu and to develop their playwriting skills CONCLUSION: The findings contribute to the corpus of pedagogies for the teaching of vocabulary in African languages, which includes writing the texts and aiming to use these for reading experience and for dramatic activity in early grades classrooms CONTRIBUTION: The contribution of this study is how playwriting can serve as a pedagogical tool for the teaching of reading and vocabulary in the primary school