The in silico study aimed to suggest phytochemicals from Commiphora leptophloeos leaves essential oil as therapies against coronavirus disease (COVID-19) (or severe acute respiratory syndrome coronavirus 2, SARS-CoV-2). For that, we used molecular docking (MD), absorption, distribution, metabolism, excretion, and toxicity (ADMET) parameters, and pharmacokinetic analysis. MD showed the presence of hydrophobic and hydrogen bonds for nine compounds. β-Selinene and bicyclogermacrene showed the best interaction values with the protein Mpro (ID: 6Y2F) (-5.9) and chimeric receptor complexed with its receptor human ACE2 (ID: 6VW1) (-6.1 and -5.5) proteins, as well as low gastrointestinal and high epithelial absorptions, medium permeability for Caco-2 cells and high epithelial permeability, low oral excretion, and were inhibitors of CYP2C19 and CYP2C9 enzymes. On the other hand, both were not permeable to the blood-brain barrier and inhibitors or substrates for glycoprotein-D, and showed carcinogenic potential, but only β-selinene was considered mutagenic. Although little bioavailable, both presented aspects structurally adequate, being compounds with moderate synthesis difficulty. Therefore, more analyses are necessary to evaluate the mechanism of action and unsatisfactory parameters foreseen in bioinformatic assays. COVID19 COVID 19 (COVID-19 2 SARSCoV2. SARSCoV2 SARSCoV SARS CoV . SARS-CoV-2) that MD, , (MD) absorption distribution metabolism excretion ADMET (ADMET analysis βSelinene β Selinene ID (ID 6Y2F YF Y F 5.9 59 5 9 (-5.9 ACE 6VW1 VW 6.1 61 6 1 (-6. 5.5 55 -5.5 proteins absorptions Caco2 Caco Caco- CYPC CYP C CYP2C1 CYP2C enzymes hand bloodbrain blood brain glycoproteinD, glycoproteinD glycoprotein D, D glycoprotein-D potential βselinene selinene mutagenic bioavailable adequate difficulty Therefore assays COVID1 (COVID-1 SARS-CoV-2 (MD 5. (-5. 6VW 6. (-6 -5. (COVID- SARS-CoV- (-5 (- -5 (COVID SARS-CoV ( -

RESUMO: O estudo foi realizado em um ovino, fêmea, de três anos de idade, da raça santa inês, procedente de uma propriedade localizada do município de Santo Antônio de Tauá, oeste do Pará. O animal acometido tinha histórico de exoftalmia no olho esquerdo, secreção nasal e dificuldade respiratória há mais de três meses. Ao exame físico o animal apresentava baixo escore corporal, apatia, assimetria facial unilateral, moderada exoftalmia unilateral esquerda, dispneia mista e exsudação nasal serossanguinolenta profusa unilateral. À necropsia, foi observada grande massa nasal, predominantemente branco-amarelada com áreas vermelho enegrecidas, de superfície irregular, finamente granular, úmida e friável. A massa invadia desde a junção mucocutânea do nariz esquerdo até as coanas, se infiltrava pelos seios nasais frontais, placa cribiforme e alcançava as meninges e a porção frontal do cérebro. À microscopia da superfície do epitélio nasal notou-se severa destruição dos cornetos e dos epitélios, evidenciada por extensas áreas de necrose com muitos debris celulares, ulceração e infecção bacteriana secundária. No sistema nervoso central (SNC) havia meningite piogranulomatosa com acentuada congestão de vasos, focos de necrose e inflamação granulomatosa. O diagnóstico de rinite granulomatosa de origem micótica associada ao fungo Conidiobolus lamprauges foi baseado nos achados da imuno-histoquímica. RESUMO ovino fêmea idade inês Tauá Pará meses corporal apatia esquerda necropsia brancoamarelada branco amarelada enegrecidas irregular granular friável coanas frontais cérebro notouse notou epitélios celulares secundária SNC (SNC vasos imunohistoquímica. imunohistoquímica imuno histoquímica. histoquímica imuno-histoquímica

ABSTRACT: The study was conducted on a 3-year-old female Santa Inês sheep from a property located in the municipality of Santo Antônio de Tauá, west of Pará. The affected animal had a history of exophthalmos in the left eye, nasal discharge, and breathing difficulty for more than three months. On physical examination, the animal had a low body score, apathy, unilateral facial asymmetry, moderate unilateral left exophthalmos, mixed dyspnea and unilateral profuse serosanguinous nasal discharge. At necropsy, a large nasal mass was observed, predominantly yellowish-white with blackish-red areas, with an irregular, finely granular, moist, and friable surface. The mass invaded from the mucocutaneous junction of the left nostril to the choanae, infiltrated the frontal sinuses, the cribiform plate, and reached the meninges and the frontal portion of the brain. Microscopy of the surface of the nasal epithelium showed severe destruction of the turbinates and epithelia, evidenced by extensive areas of necrosis with a large amount of cellular debris, ulceration, and secondary bacterial infection. In the central nervous system there was pyogranulomatous meningitis with marked vessel congestion, as well as foci of necrosis and granulomatous inflammation. Immunohistochemistry showed intense staining of numerous intralesional hyphae for antibodies against Conidiobolus lamprauges. The diagnosis of granulomatous rhinitis of mycotic origin associated with the Conidiobolus lamprauges was based on epidemiological, clinical-pathological, and immunohistochemical data. ABSTRACT 3yearold yearold 3 year old Tauá Pará eye discharge months examination score apathy asymmetry necropsy observed yellowishwhite yellowish white blackishred blackish red irregular granular moist choanae sinuses plate brain epithelia debris ulceration infection congestion inflammation epidemiological clinicalpathological, clinicalpathological clinical pathological, pathological clinical-pathological data

Abstract In the diagnosis of diffuse interstitial lung diseases, the gold standard is multidisciplinary evaluation. This means a clinical, radiological and histopathological consensus. The ideal is to have an experienced team of specialists, mainly in cases that present difficulty in definitive diagnosis, without categorical characteristics of a specific pathology. High-resolution computed tomography is the imaging test of choice that contributes to the definitive diagnosis. The purpose of this article is to analyze the imaging patterns of idiopathic fibrotic diseases: usual interstitial pneumonia, idiopathic pulmonary fibrosis, combined pulmonary fibrosis and emphysema, non-specific interstitial pneumonia and pleuroparenchymal fibroelastosis. Initially we will also analyze the interstitial lung abnormality. Finally, we will refer to the growing use of artificial intelligence in the evaluation and progression of diffuse lung diseases, and to the application of a recently developed technique, photon counting computed tomography.

Resumen En el diagnóstico de las enfermedades pulmonares intersticiales difusas, el método de referencia es la evaluación multidisciplinaria. Esto significa un consenso clínico, radiológico e histopatológico. Lo ideal es contar con un equipo experimentado de especialistas, principalmente en casos que presentan dificultad en el diagnóstico definitivo, sin características categóricas de una patología específica. La tomografía computada de alta resolución es la prueba de imagen de elección que contribuye en el diagnóstico definitivo. El propósito de este artículo es analizar los patrones imagenológicos de las enfermedades idiopáticas fibróticas: fibrosis pulmonar usual o idiopática, fibrosis pulmonar y enfisema combinados, fibrosis pulmonar no específica y fibroelastosis pleuroparenquimatosa. Analizaremos además al inicio la anormalidad pulmonar intersticial. Finalmente, haremos referencia al creciente uso de la inteligencia artificial en la evaluación y la progresión de las enfermedades pulmonares difusas, y a la aplicación de una técnica de desarrollo reciente, la tomografía computada con conteo de fotones.

Resumo No Brasil, construções em madeira do tipo light woodframe possuem envelopamento estrutural do painel dependente do uso de chapas de OSB (Oriented Strand Board), o que implica em uma dificuldade em seu acesso por parte da população. Para ampliar a aplicação do sistema, uma possibilidade consiste em um projeto não atrelado aos monopólios de componentes construtivos. Uma possibilidade é a substituição da camada de envelopamento estrutural dos painéis por tábuas de madeira serrada convencional. Como objetivo esta pesquisa analisa a viabilidade de utilização e o comportamento de painéis de madeira serrada com envelopamento em tábuas de pinus quando solicitados a esforços horizontais, utilizando modelo numérico de simulações em software. O trabalho estuda cinco diferentes tipologias de painéis: um modelo digital de calibração baseado em experimento ensaiado em laboratório; quatro modelos de diferentes configurações, comparando entre si o desempenho estrutural de cada um com dados publicados na literatura. A modelagem digital utilizou dados experimentais já obtidos em trabalhos anteriores. Dos cinco tipos estudados quanto à tensão-deformação, apenas o Modelo 05 não se mostrou viável pela alta concentração de tensão observada nos conectores. Os demais modelos se mostraram adequados aos critérios preconizados por normas e documentos técnicos referenciados. Brasil Oriented Board, Board , Board) população sistema construtivos convencional horizontais software laboratório configurações literatura anteriores tensãodeformação, tensãodeformação deformação, deformação tensão-deformação 0 conectores referenciados

Abstract In Brazil, light woodframe buildings rely on the use of OSB (Oriented Strand Board), what implies a difficulty in its access by part of the population. To increase the applicability of the system one proposition consists in a woodframe project that is not bound by the monopoly over constructive components. A possible way consists in the substitution of the coating of the panels with standard Pinus boards. The objective of this research is therefore to analyze the viability and the behavior of wood panels with Pinus board coating when submitted to horizontal loads, utilizing as method digital simulations. This paper lists five different panel topologies, to calibrate it: one digital model of a previous lab experiment; four panels with different configurations, comparing them between themselves and with the literature in regards of structural performance. The utilized method was of the digital simulation with previous laboratory data calibration. Among the five types studied, only Model 05 exhibited high stress concentrations at connectors, rendering it unviable. The other models meet the criteria of referenced standards and technical documents. Brazil Oriented Board, Board , Board) population components boards loads simulations topologies experiment configurations performance calibration studied 0 connectors unviable documents

Resumen El duelo por finalización de una relación de pareja puede ser una experiencia que genera diferentes afectaciones, y para lidiar con ello, las personas utilizan diversos recursos de afrontamiento. El presente estudió buscó identificar las diferentes estrategias de afrontamiento que utilizan las personas en duelo de pareja en general y según el tiempo de finalización del vínculo. Esta investigación, de enfoque cuantitativo, alcance descriptivo no experimental y de corte transversal, fue realizada con 172 participantes, elegidos en un muestro a conveniencia. Se evidenció en los resultados que las estrategias que presentaron menor uso fueron la búsqueda de solución de problemas y la reevaluación positiva, y las más utilizadas fueron la búsqueda de apoyo social, la espera, religión, evitación emocional, el apoyo profesional, la reacción agresiva, la evitación cognitiva y la expresión de dificultad de afrontamiento. A nivel del tiempo de la finalización de la relación, se encontró mayor uso de la evitación emocional, reacción agresiva, evitación cognitiva y el apoyo profesional en aquellos con 6 meses de duelo, y menor uso de la reevaluación positiva, búsqueda de apoyo social, solución de problemas, negación, expresión de la dificultad de afrontamiento y autonomía en este periodo de tiempo. En conclusión, se identificó que las estrategias para afrontar el duelo en pareja varían conforme avanza el tiempo de la finalización del vínculo.

Abstract Grieving duel to the end of a relationship can be an experience that generates different effects and, to deal with it, people use various coping resources. The present study sought to identify the different coping strategies used by bereaved couples in general and according to the time the relationship ended. This research with a quantitative approach, non-experimental and cross-sectional descriptive scope, was carried out with 172 subjects chosen in a convenience sample. The results showed that the strategies that were least used were the search for problem solutions and positive reappraisal and the most used were the search for social support, waiting, religion, emotional avoidance, professional support, aggressive reaction, cognitive avoidance and the expression of coping difficulty. At the time of the end of the relationship, greater use of emotional avoidance, aggressive reaction, cognitive avoidance and professional support was found in those with 6 months of grief and less use of positive reappraisal, search for social support, solution of problems, denial, expression of coping difficulty and autonomy in this period of time. In conclusion, it was identified that the strategies for coping with grief as a couple vary as the time of the end of the relationship progresses.

Abstract This article analyzes abortion experiences with misoprostol during the first decade of the 21st century in Argentina, before the legalization of the practice and the publication of the World Health Organization manuals on medication dosage. Based on in-depth interviews with women who underwent medical abortions during those years, we inquire about the mechanisms of information circulation and clandestine purchase of the drug. In addition, the article delves into experiences on the use of medication, confidence in the procedure, and the pain felt by these women from the theoretical perspective of the sociology of emotions. Among the most relevant findings is that women build networks and links to overcome the problems surrounding the practice of abortion because of the difficulty of obtaining the medication in the context of legality and illegality and the lack of information about the procedure itself and to develop a reliable method based on their own experiences.

Resumen En el presente artículo se analizan experiencias de aborto con misoprostol durante la primera década del siglo XXI en Argentina, antes de la legalización de la práctica y de la publicación de los manuales de la Organización Mundial de la Salud respecto a la posología de la medicación. A partir de entrevistas en profundidad a mujeres que se practicaron abortos medicamentosos en esos años, se indaga acerca de los mecanismos de circulación de información y de compra clandestina de la droga. Además, se ahonda en las experiencias sobre el uso de la medicación, la confianza en el procedimiento y el dolor sentido por estas mujeres desde la perspectiva teórica de la sociología de las emociones. Entre los hallazgos más relevantes se encuentra la constatación de que las mujeres construyeron sus redes y vínculos para sortear los problemas en torno a la práctica del aborto, tanto por la dificultad de conseguir la medicación en el marco de la legalidad e ilegalidad como por la falta de información sobre el procedimiento en sí mismo y la construcción de un método confiable a partir de sus propias experiencias.

Resumen Descripción del caso: Paciente de 23 años con hemorragia abdominal de origen no claro, que posteriormente presenta inestabilidad hemodinámica, requiriendo manejo quirúrgico en tres ocasiones con evolución satisfactoria. Hallazgos clínicos: Presentó sangrado cuantificado de 5500 cc en cavidad abdominal (grado IV - clasificación ATLS) con lesiones hepáticas en los segmentos I, IV y VIII, sin hallazgos sugestivos de trauma al examen físico, ni otros hallazgos traumáticos internos. Tratamiento y resultados: Se llevó a cabo una intervención quirúrgica precoz mediante laparotomía exploratoria con hallazgos ya descritos, además de dos tiempos quirúrgicos adicionales que llevaron al control del sangrado, con evolución satisfactoria. Relevancia clínica: El sangrado abdominal y laceración de víscera sólida secundario a trauma cerrado de abdomen es una etiología común en pacientes jóvenes masculinos, siendo contrario a esta afirmación el sangrado de origen hepático sin trauma es una etiología poco común. El presente caso resulta ser una dificultad diagnóstica en cuanto a la etiología, ya que lo evidenciado en la exploración quirúrgica no concuerda con el examen físico externo, sin una historia clínica clara al ingreso se deja la interrogante de la causa.

Summary: Case description: 23-year-old patient with abdominal hemorrhage of unclear origin, who subsequently presented hemodynamic instability, requiring surgical management on three occasions with satisfactory evolution. Clinical findings: she presented quantified bleeding of 5500 cc in the abdominal cavity (grade IV-ATLS classification) with liver lesions in segments I, IV and VIII, without findings suggestive of trauma on physical examination, or other internal traumatic findings. Treatment and results: An early surgical intervention was carried out through exploratory laparotomy with findings already described, in addition to two additional surgical procedures that led to control of bleeding, with satisfactory evolution. Clinical relevance: Abdominal bleeding and solid viscus laceration secondary to blunt abdominal trauma is a common etiology in young male patients, contrary to this statement, bleeding of hepatic origin without trauma is a rare etiology. The present case turns out to be a diagnostic difficulty in terms of etiology, since what was evidenced in the surgical exploration does not agree with the external physical examination, without a clear clinical history at admission, the question of the cause is left.

Resumen Aunque no es muy común, en los últimos 20 años se ha observado un aumento significativo en los reportes de rotura del pectoral mayor, normalmente asociado a la práctica de actividad física en la que se produce una contracción intensa y/o al uso de cargas pesadas ejerciendo resistencia sobre el mismo. el músculo. En este caso clínico tenemos un paciente de 51 años que refiere dolor en el pecho derecho y en el brazo derecho durante 3 días después de intentar arreglar el manillar de su motocicleta. Presentó asimetría de pectorales, pérdida de fuerza en miembro superior derecho, dificultad de movimiento y hematoma. La resonancia magnética demostró rotura completa de la unión miotendinosa del pectoral mayor, con tendinopatía con fisuras de inserción e intrasustancial del infraespinoso y tendinopatía con rotura parcial del tendón subescapular. Un médico ortopédico recomendó seguimiento con el uso de medicación analgésica.

Resumo Apesar de não muito frequente, nos últimos 20 anos, houve um aumento significativo dos relatos sobre rotura do peitoral maior, normalmente associadas à prática de atividade física em que ocorre contração intensa e/ou uso de cargas pesadas exercendo resistência sobre o músculo. Neste relato de caso temos um paciente de 51 anos referindo dor no tórax à direita e no braço direito há 3 dias após tentar consertar o guidão da moto. Apresentava assimetria dos peitorais, perda de força do membro superior direito, dificuldade de movimentação e hematoma. A ressonância magnética demonstrou rotura completa da junção miotendínea do peitoral maior, com tendinopatia com fissuras insercionais e intrasubstanciais infraespinhal e tendinopatia com rotura parcial do tendão subescapular. Foi indicado por médico ortopedista o acompanhamento com o uso de medicação analgésica.

Abstract Although not very common, in the last 20 years, there has been a significant increase in reports of rupture of the pectoralis major, normally associated with the practice of physical activity in which intense contraction occurs and/or the use of heavy loads exerting resistance on the muscle. In this case report we have a 51-year-old patient reporting pain in his right chest and right arm for 3 days after trying to fix his motorcycle's handlebars. He had asymmetry of the pectorals, loss of strength in the right upper limb, difficulty moving and hematoma. Magnetic resonance imaging demonstrated complete rupture of the myotendinous junction of the pectoralis major, with tendinopathy with insertional and intrasubstantial infraspinatus fissures and tendinopathy with partial rupture of the subscapularis tendon. An orthopedic doctor recommended follow-up with the use of analgesic medication.

ABSTRACT This paper proposes a composite indicator to identify levels of water security at the household-community interface. It analyses the hydro-social processes that give rise to water scarcity situations experienced by the rural population supplied by community organizations in rural Chile. The indicator is based on a case study of ten community organizations selected to represent the heterogeneity existing in the country, where semi-structured interviews with their leaders and field observations were applied. Two main findings emerge from the study: 1) there is no correlation between the size of organizations and the levels of observed water security; 2) cases with greater difficulty accessing sufficient resources are not the ones facing greater water insecurity, as organizations compensate for this difficulty with other components.

RESUMEN El presente artículo propone un indicador compuesto que permite identificar niveles de seguridad hídrica en la interfaz doméstica-comunitaria. Para ello analiza los procesos hidrosociales que dan origen a situaciones de escasez hídrica vividas por la población rural abastecida mediante organizaciones comunitarias en Chile rural. El indicador se basa en el estudio de caso de diez organizaciones comunitarias seleccionadas para representar la heterogeneidad existente en el país, a cuyos dirigentes se les aplicó entrevistas semiestructuradas en las cuales se realizaron, además, observaciones de campo. Del estudio se desprenden dos principales hallazgos: 1) No existe una correlación entre el tamaño de las organizaciones y los niveles de seguridad hídrica observados; 2) Los casos con mayores dificultades para acceder a recursos en cantidad suficiente no son los que enfrentan una inseguridad hídrica mayor, puesto que las organizaciones compensan esta dificultad con otros componentes.

Abstract Introduction In clinical practice, patients with the same degree and configuration of hearing loss, or even with normal audiometric thresholds, present substantially different performances in terms of speech perception. This probably happens because other factors, in addition to auditory sensitivity, interfere with speech perception. Thus, studies are needed to investigate the performance of listeners in unfavorable listening conditions to identify the processes that interfere in the speech perception of these subjects. Objective To verify the influence of age, temporal processing, and working memory on speech recognition in noise. Methods Thirty-eight adult and elderly individuals with normal hearing thresholds participated in the study. Participants were divided into two groups: The adult group (G1), composed of 10 individuals aged 21 to 33 years, and the elderly group (G2), with 28 participants aged 60 to 81 years. They underwent audiological assessment with the Portuguese Sentence List Test, Gaps-in-Noise test, Digit Span Memory test, Running Span Task, Corsi Block-Tapping test, and Visual Pattern test. Results The Running Span Task score proved to be a statistically significant predictor of the listening-in-noise variable. This result showed that the difference in performance between groups G1 and G2 in relation to listening in noise is due not only to aging, but also to changes in working memory. Conclusion The study showed that working memory is a predictor of listening performance in noise in individuals with normal hearing, and that this task can provide important information for investigation in individuals who have difficulty hearing in unfavorable environments. practice loss factors sensitivity Thus subjects age processing Thirtyeight Thirty eight G1, G , (G1) 1 2 3 years G2, (G2) 6 8 Test GapsinNoise Gaps Noise test BlockTapping Block Tapping listeninginnoise variable aging environments (G1 (G2 (G

Abstract Introduction Eagle syndrome is a rare and an often misdiagnosed entity in otorhinolaryngology. Objective To determine the efficacy of the surgical treatment for Eagle syndrome. Methods The present prospective study included 25 patients who presented with complaints of pain in the throat, ear, and neck, as well as difficulty and/or pain while swallowing; they were assessed for Eagle syndrome. As per patient profile, we performed a clinical assessments along with orthopantomograms (OPGs), three-dimensional computed tomography (3D CT) scans, and cone beam computed tomography (CBCT). Pain was assessed pre- and postoperatively through the Numerical Rating Scale-11 (NRS-11), whose score ranges from 0 to 10. Microscopic tonsillo-styloidectomy was performed in cases in which the conservative treatment failed to relieve pain. Results The mean age of the entire study population was of 36.08 ± 7.19 years, and the male-to-female ratio was of 1.08:1. Referred otalgia was the commonest (44%) complaint. Radiologically, out of 25 patients, 20 patients presented elongated styloid processes. The longest symptomatic styloid process measured radiographically was of 64.7 mm while the shortest was of 28.2 mm. Out of 20 patients, 12 underwent surgery. The postoperative pain assessment through the NRS-11 was performed on day 0 (3.83 ± 0.83), day 7 (1.5 ± 0.52), week 4 (0.5 ± 0.52), and week 12 (0.41 ± 0.51). By 12 weeks, 7 patients were symptom-free, while 5 patients still reported mild pain. Conclusion Eagle syndrome associated with an elongated styloid process is not a rarity, but it often goes undiagnosed. Microscopic tonsillo-styloidectomy shows excellent results in the management of patients with Eagle syndrome. otorhinolaryngology 2 throat ear neck andor or swallowing profile OPGs, OPGs , (OPGs) threedimensional three dimensional 3D D CT scans CBCT. CBCT . (CBCT) pre Scale11 Scale 11 Scale-1 NRS11, NRS11 NRS (NRS-11) 10 tonsillostyloidectomy tonsillo styloidectomy 3608 36 08 36.0 719 19 7.1 years maletofemale male female 1.081. 1081 1.08 1. 1 1.08:1 44% 44 (44% complaint Radiologically processes 647 64 64. 282 28 28. surgery NRS-1 3.83 383 3 83 (3.8 0.83, 083 0.83 0.83) 1.5 15 (1. 0.52, 052 0.52 52 0.52) 0.5 05 (0. 0.41 041 41 (0.4 0.51. 051 0.51 51 0.51) weeks symptomfree, symptomfree symptom free, free symptom-free rarity undiagnosed (OPGs (CBCT Scale1 Scale- NRS1 (NRS-11 360 36. 71 7. 081 1.081 108 1.0 1.08: (44 6 NRS- 3.8 38 8 (3. 0.8 (1 0. (0 0.4 04 (NRS-1 (4 3. (3 ( (NRS- (NRS

Abstract Introduction The presence of foreign bodies in the airways remain a diagnostic challenge to healthcare professionals. They can become life threatening emergencies that require immediate intervention or go unnoticed for weeks and even months. Prevention is best but early recognition remains a critical factor in treatment of foreign body inhalation in children. Objective To study the diagnostic advantages of virtual over rigid bronchoscopy in the evaluation of children with suspected foreign body in the tracheobronchial tree and plan for early management. Methods A crossectional study conducted at a tertiary care hospital & medical college in India. A total 24 patients (0-12-years-old) who presented with complaints of sudden onset of coughing, choking, and breathing difficulty were included during the 2-year duration, from January 2018 to December 2019. All patients underwent virtual and rigid bronchoscopy. Results In 8 patients, foreign bodies detected by virtual bronchoscopy were confirmed by rigid bronchoscopy. There was one case in which virtual bronchoscopy showed no foreign body, but rigid bronchoscopy detected it. In 15 cases virtual and rigid bronchoscopy did not show foreign bodies. The sensitivity, specificity, positive and negative predictive value of virtual bronchoscopy were 88.88, 100, 100, and 93.75%, respectively. Conclusions Virtual bronchoscopy is less invasive and does not require general anesthesia but cost and availability are limitations. It can be used as method of investigation in children with suspected foreign body aspiration. professionals months management India 2 012yearsold yearsold 0 12 years old (0-12-years-old coughing choking 2year year duration 201 2019 it 1 sensitivity specificity 8888 88 88.88 100 9375 93 75 93.75% respectively limitations aspiration 20 888 88.8 10 937 9 7 93.75 88. 93.7 93.

Abstract Introduction. The COVID-19 infection drastically affected health care worldwide, creating challenges for primary care. In order to mitigate and manage infection, telemedicine has become an emerging and effective modality in several medical specialties, including head and neck surgery. Methods. Retrospective cross-sectional analysis of patients seen in virtual consultation over 18 months. Absolute and relative frequencies were estimated, univariate analysis was done with chi-square, and bivariate analysis with binary logistic regression. Variables such as primary diagnosis, the resolution power of the consultation, the need for an in-person appointment, the platform, and its difficulties were included. Results. 2485 patients from 11 departments were included. Thyroid pathology was the most frequent (62.9%), followed by aerodigestive tract pathology (10.8%). The consultation was efficient in 99% of cases, with a resolution capacity of 96.4%. 1.4% had difficulties on the platform and 8.3% of patients required an in-person. When there was difficulty in reviewing exams or an inadequate functional inspection, it was 30 times more likely to not be able to efficiently be resolved. Conclusion. Telemedicine provides an efficient alternative for care in head and neck surgery, especially in thyroid pathology controls, avoiding unnecessary travel. In the aerodigestive tract, where the physical examination is essential, its usefulness is limited to the possibility of performing a subsequent endoscopic examination that allows adequate staging and facilitates in-person assessment.

Resumen Introducción. La infección por COVID-19 afectó drásticamente la atención en salud a nivel mundial, generando retos para la atención primaria. En orden de mitigar y manejar el contagio, la telemedicina se convirtió en una modalidad emergente y efectiva en varias especialidades médicas, incluida la cirugía de cabeza y cuello. Métodos. Estudio de corte transversal con análisis retrospectivo de pacientes atendidos en la consulta virtual durante 18 meses. Se estimaron frecuencias absolutas y relativas, y bivariado con regresión logística binaria. Se incluyeron las variables de diagnóstico primario, poder resolutivo de la consulta, necesidad de cita presencial, plataforma y dificultades de la misma. Resultados. Se incluyeron 2485 pacientes provenientes de 11 departamentos. La patología tiroidea fue la más frecuente (62,9 %), seguida de la aerodigestiva (10,9 %). La consulta fue eficiente en el 99 % de los casos, con una capacidad resolutiva del 96,4 %. El 1,4 % tuvo dificultades en la plataforma y el 8,3 % de los pacientes requirió cita presencial. Cuando hubo dificultad para la revisión de exámenes o una inadecuada inspección funcional, fue 30 veces más probable no poder resolver eficientemente la consulta. Conclusión. La telemedicina provee una alternativa eficiente de atención en cirugía de cabeza y cuello, especialmente en los controles de patología tiroidea, evitando desplazamientos innecesarios. En el tracto aerodigestivo, donde el examen físico es primordial, su utilidad está limitada a la posibilidad de realizar un examen endoscópico posterior que permita una adecuada estadificación y facilite la valoración presencial.

Abstract Every year, thousands of students enter higher education, often facing personal and academic This study consists of the first national mapping of hate crimes with homophobic and/or transphobic motivations against sexual and gender diversity in Portugal. The objective of this article focuses on analyzing the process of monitoring and stratifying hate crimes with homophobic and/or transphobic motivations by the Portuguese State, verifying their specificities as a result of the current legal framework and the phenomena of underreporting, revictimization and impunity for these crimes. cases. This investigation carried out the mapping and identification of 33 Criminal Investigations, belonging to 20 districts of the Public Ministry between 2015 and 2020. After the identification of the Unique Crime Process Identifier Number - NUIPC by the Judiciary Police and authorization to consult the procedural documents to the Departments of Investigation and Criminal Action - DIAPs of the MP, the data collection process was carried out in 29 Criminal Inquiries. The present investigation consists of a descriptive study of mixed methods, carried out through document analysis through content analysis, with regard to data processing. The data collection instrument was supported by case reporting documents, notably: reporting records, news records and emails with records of criminal complaints. The complaints analyzed highlight the need to review the Brazilian legal framework in relation to hate crimes with homophobic and transphobic motivations, considering the “invisibility” of these records for official statistics and the absence of specific fields that collaborate in the process of identifying the motivation of these cases, as well as the difficulty in recognizing this violence by the competent authorities as hate crimes against Sexual Orientation Gender Identity Gender Expressions and Sexual Characteristics - OIEC of its victims, contexts that strengthen the process of invisibility of this data in Portugal, supporting the false statement that: “Everything is fine here!” when we consider the reality of this violence perpetrated daily in the country.

Resumo Este estudo consiste no primeiro mapeamento nacional de crimes de ódio com motivações homofóbicas e/ou transfóbicas contra a diversidade sexual e de género em Portugal. O Objetivo deste artigo centra-se na análise do processo de monitorização e estratificação dos crimes de ódio com motivações homofóbicas e/ou transfóbicas pelo Estado português, verificando suas especificidades em decorrência do enquadramento jurídico atual e dos fenómenos da subnotificação, revitimização e da impunidade destes casos. A referida investigação realizou o mapeamento e identificação de 33 Inquéritos Criminais, pertencentes à 20 comarcas do Ministério Público entre 2015 e 2020. Após a identificação do Número Único de Identificador de Processo Crime - NUIPC pela Polícia Judiciária e autorização para consulta das peças processuais aos Departamentos de Investigação e Ação Penal - DIAPs do MP, o processo de levantamento de dados foi realizado em 29 Inquéritos Criminais. A presente investigação, consiste em um estudo discritivo de métodos mistos, realizado através de análise documental por meio da análise de conteúdo, no que concerne ao tratamento de dados. O instrumento de levantamento de dados foi sustentado por documentos de denúncias de casos, designadamente: autos de denúncias, autos de notícias e e-mails com registos de queixas-crimes. As denúncias analisadas destacam a necessidade da revisão do enquadramento jurídico português em relação aos crimes de ódio com motivações homofóbicas e transfóbicas considerando a “invisibilidade” destes registos para estatísticas oficiais e a ausência de campos específicos que colaborem no processo de identificação da motivação destes casos, bem como a dificuldade do reconhecimento desta violência pelas autoridades competentes enquanto crimes de ódio contra a Orientação Sexual Identidade de género Expressões de género e Características Sexuais - OIEC de suas vítimas, contextos estes que fortalecem o processo de invisibilidade destes dados em Portugal sustentando a falsa afirmação de que: “Por aqui está tudo bem!” ao considerarmos a realidade desta violência perpetrada cotidianamente no país.

Abstract One of the demands of the academic community for the selection and accreditation processes of their members is to lead competitive research projects. Many young researchers face the challenge of being a “Principal Investigator” for the first time without prior experience or support. To this end, we believe that it is necessary to share experiences of presenting subsidized projects (also failures) among the academic community. The objective of this article is twofold: on the one hand, to consider the difficulty of structuring research projects to receive grants from the institutions and, on the other, to share and discuss strategies and complexities of the qualitative approach based on the project proposal made by the author. The referred project was presented in the 2021 call for "Proyectos de Generación de Conocimiento " of the Ministry of Science and Innovation of Spain. The proposal is based on the fact that the transition from modernity to post-modernity materialises in different dimensions and processes that are relevant to their study from the social sciences perspective. One of them is the management of imaginaries associated to motherhood as a representative institution of a particular geographical and historical context. Understanding the associated processes, representations and narratives on motherhood is one of the challenges concerning today's society as a whole, not just women and mothers. The general objective of this project is to delve into the narratives of women and mothers who break (or wish to break) with the practices and meanings associated with "traditional motherhood". Thus, we aim to explore the processes of change, continuity, and subversion in the motherhood management within the framework of advanced modern or post-modern societies.

Resumo Una de las exigencias de la comunidad académica para los procesos de selección y acreditación de profesorado es la de dirigir proyectos de investigación competitivos subvencionados. Muchos jóvenes investigadores se encuentran con el reto de ser Investigador Principal (en adelante: IP) por primera vez sin experiencia previa o soporte. Creemos que es necesario compartir experiencias de presentación de proyectos subvencionados (también de fracaso) entre la comunidad académica y, especialmente, entre los jóvenes investigadores que empiezan a presentar proyectos de equipo como IP’s. Observamos, para el caso que nos ocupa, ciertas complejidades añadidas en proyectos pensados mediante diseño cualitativo debido, entre otros factores, al grado de sistematización, previsión y concreción a seguir. El objetivo principal de este artículo es el de reflexionar sobre algunas dificultades de estructurar y justificar proyectos de investigación de corte cualitativo con el fin de recibir financiación en el campo de las ciencias sociales. Con la convicción de la necesidad de compartir experiencias entre la comunidad académica, aquí se utiliza el ejemplo de un proyecto de investigación presentado en la convocatoria 2021 de “Proyectos de Generación de Conocimiento” del Ministerio de Ciencia e Innovación de España. La temática del proyecto presentado refiere a la gestión de los imaginarios sobre la maternidad como institución social y política. La propuesta, de corte cualitativo, parte de la base que el tránsito de la modernidad a la posmodernidad se materializa en diferentes dimensiones y procesos asociados relevantes para el estudio desde las ciencias sociales. Una de ellas es la gestión de los imaginarios sobre la maternidad como institución representativa de un contexto geográfico e histórico determinado.