RESUMO Objetivo: Reconhecer e abordar a síndrome de Patau, apesar de sua raridade e da baixa expectativa de vida associada, por meio da apresentação de um estudo de caso de uma paciente de dois anos que recebe cuidados em casa por intermédio de serviços de home care. Descrição do caso: Apresentamos uma paciente do sexo feminino que desafiou as probabilidades, com sobrevivência prolongada devida, possivelmente, ao home care. Ela nasceu por cesariana, com 31 semanas + 4 dias, em razão da restrição do crescimento uterino. A mãe, de 36 anos, recebeu cuidados pré-natais adequados e gozava de boa saúde. O diagnóstico da síndrome de Patau foi confirmado por meio de cariótipo após o nascimento. Apesar da gravidade clínica do caso, a paciente, hoje com dois anos, recebe atendimento domiciliar especializado, apoiado por traqueostomia e gastrostomia. Um técnico de enfermagem dedicado 24 horas garante acompanhamento contínuo, e a paciente beneficia-se de check-ups médicos regulares, fisioterapia cinco vezes por semana, sessões semanais de fonoaudiologia, consultas mensais com nutricionista e apoio psicológico contínuo aos familiares. Comentários: Esta abordagem multidisciplinar resultou em melhora motora discreta, destacando o impacto positivo do cuidado integral no seu bem-estar geral. A existência de uma rede robusta de apoio às famílias que enfrentam desafios semelhantes é crucial, e um cuidado multidisciplinar pode prevenir eficazmente as complicações associadas a esta impactante síndrome. Objetivo associada care probabilidades devida possivelmente cesariana 3 dias uterino mãe prénatais pré natais saúde nascimento especializado gastrostomia 2 beneficiase beneficia se checkups check ups regulares semana fonoaudiologia familiares Comentários discreta bemestar bem estar geral crucial

ABSTRACT Objective: To recognize and address Patau’s syndrome, despite its rarity and associated low life expectancy, through the presentation of a case study of a 2-year-old patient receiving Home Care services. Case description: We present a female patient who defied the odds with a prolonged survival, possible due to Home Care. She was delivered via cesarean section at 31 weeks + 4 days due to restricted uterine growth. The mother, aged 36, had received proper prenatal care and was in good health. The diagnosis of Patau’s syndrome was confirmed through karyotyping after birth. Despite the severe clinical nature of the case, the patient, now with two years old, receives specialized home-based care, supported by a tracheostomy and gastrostomy. A dedicated 24-hour nursing technician ensures continuous monitoring, and the patient benefits from regular medical check-ups, physiotherapy five times a week, weekly speech therapy sessions, monthly consultations with a nutritionist, and ongoing psychological support for her family members. Comments: This multidisciplinary approach has resulted in a slight motor response, highlighting the positive impact of comprehensive care on her overall well-being. The existence of a robust support network for families facing similar challenges is crucial, and a multidisciplinary care can effectively prevent complications associated with this impactful syndrome. Objective Pataus Patau s expectancy 2yearold yearold 2 year old services description survival 3 growth mother 36 health birth homebased home based gastrostomy 24hour hour 24 monitoring checkups, checkups check ups, ups check-ups week sessions nutritionist members Comments response wellbeing. wellbeing well being. being well-being crucial

ABSTRACT Purpose: Although Brazil has a high prevalence of retinoblastoma, there is a lack of epidemiological data on the disease. Thus, in this study, we aimed to evaluate the epidemiological profile of patients diagnosed with retinoblastoma in the ophthalmology department of a pediatric tertiary referral hospital in Ceara, Brazil. Methods: A descriptive and cross-sectional study was conducted by retrospectively analyzing the clinical and socioeconomic data from the medical records of pediatric patients followed-up at the hospital between 2007 and 2021. Retinoblastoma was diagnosed on the basis of a fundoscopic or histopathologic examination. Results: The data of 105 patients were included in the study, and the mean patient age at the time of diagnosis was 1.7 years. Most of the patients were women (50.5%) and hailed from rural areas (57.4%), which was associated with a higher tumor stage. Of the 150 patients, 57.1% initially presented with leukocoria. Ocular hyperemia was associated with more advanced stages of retinoblastoma (p=0.004). Bilateral involvement was observed in 25.7% of the patients and at a significantly younger age (p=0.009). The presence of retinal detachment, vascularized lesions, and vitreous seeds significantly increased the likelihood of requiring enucleation. Discussion: This study presents an epidemiological description of retinoblastoma in Brazil, which highlights the significance of early detection. Delayed diagnosis is associated with a poorer visual prognosis and higher mortality rate, particularly in patients with unilateral disease. Risk factors for a more severe disease were retinal detachment, vascularized lesions, and vitreous seeds. The correlation between histopathological features and clinical outcomes was limited. Conclusion: Further studies are required to assess the influence of ocular hyperemia, fundoscopic assessment, and histopathologic findings on the prognosis of retinoblastoma. Moreover, it is critical to devise interventions to reduce the time-to-diagnosis in rural areas. Purpose Thus Ceara Methods crosssectional cross sectional followedup followed up 200 2021 examination Results 10 17 1 7 1. years 50.5% 505 50 5 (50.5% 57.4%, 574 57.4% , 57 4 (57.4%) stage 15 571 57.1 leukocoria p=0.004. p0004 p p=0.004 . 0 004 (p=0.004) 257 25 25.7 p=0.009. p0009 p=0.009 009 (p=0.009) detachment lesions enucleation Discussion detection rate limited Conclusion assessment Moreover timetodiagnosis 20 202 50.5 (50.5 57.4 (57.4% 57. p000 p=0.00 00 (p=0.004 2 25. (p=0.009 50. (50. (57.4 p00 p=0.0 (p=0.00 (50 (57. p0 p=0. (p=0.0 (5 (57 p=0 (p=0. ( p= (p=0 (p= (p

Over the last two decades, metabolomics has emerged as a pivotal tool in multidisciplinary research, providing invaluable insights into metabolome modulations and finding applications across various scientific domains, including medicine and agronomy. Nonetheless, the absence of standardized procedures in sample preparation, data acquisition, and documentation of data quality presents a significant challenge. This review underscores the critical importance of quality assurance and quality control (QA/QC) in untargeted metabolomics, advocating for the establishment of agreed-upon QA/QC reporting standards within the scientific community. We discuss the requisite quality controls at various stages of untargeted metabolomics studies, encompassing blank samples, pooled samples, and the utilization of external quality control samples. Methods for assessing accuracy, reproducibility, and identifying/correcting batch effects are addressed. Furthermore, emphasis is placed on standardizing the description of QA/QC data in scientific publications and repositories to foster reproducibility and transparency. We recommend the publication of QC data alongside studies in appropriate databases to facilitate data comparison and sharing among researchers, thereby enhancing the quality of untargeted metabolomics research. In summary, implementing standardized QA/QC data reporting, along with promoting best practices within the untargeted metabolomics community, is crucial for improving result quality and credibility and advancing research utilizing this powerful technique. decades domains agronomy Nonetheless preparation acquisition challenge QAQC QA (QA/QC agreedupon agreed upon community samples accuracy identifyingcorrecting identifying correcting addressed Furthermore transparency researchers summary technique

RESUMO: A osteologia desempenha um papel indispensável para o conhecimento dos padrões de normalidade das diversas espécies, sendo a base para o entendimento zoológico. Mazama nana é bastante conhecido no Brasil, porém descrições morfológicas básicas acerca da espécie são escassas, enquanto Subulo gouazoubira, revalidação atual de Mazama gouazoubira, também é incidente no Brasil e, atualmente, tem sido alvo de diversos estudos filogenéticos. Nesse escopo, no presente estudo, foram preparadas, osteologicamente, 19 cabeças de cervídeos (16 Subulo gouazoubira e três Mazama nana) e, em seguida, tomografias computadorizadas (TCs) foram realizadas a fim de aprimorar as formas de avaliação de acidentes ósseos, além de estruturas internas e forames mediante técnicas de reconstrução em três dimensões (3D) devido a difícil visibilidade em peças intactas. Posteriormente, realizou-se um comparativo entre as reconstruções, fotografias digitais e secções tomográficas transversais do crânio, o qual possibilitou a visualização de peculiaridades e exclusividades anatômicas, como a presença da fenestra nasolacrimomaxilar, detalhamento dos seios paranasais e arquitetura de ossos finos, além do formato exclusivo dos ossos cranianos, em comparação a outras espécies, que apresentam um fenótipo único e genuíno. RESUMO espécies zoológico escassas atualmente filogenéticos escopo estudo preparadas osteologicamente 1 16 (1 seguida TCs (TCs ósseos 3D D (3D intactas Posteriormente realizouse realizou se reconstruções crânio anatômicas nasolacrimomaxilar finos cranianos genuíno (

ABSTRACT: Osteology plays an indispensable role in understanding the normal patterns of different species, serving as the foundation for zoological understanding. Mazama nana is well-known in Brazil; however, basic morphological descriptions of the species are scarce, while Subulo gouazoubira, currently revalidated as Mazama gouazoubira, is also prevalent in Brazil and has recently been the subject of various phylogenetic studies. In this respect, in the present study, 19 cervid heads (16 Subulo gouazoubira and three Mazama nana) were osteologically prepared. Next, computed tomographies (CTs) were performed to enhance the assessment of bone accidents, as well as internal structures and foramina through three-dimensional (3D) reconstruction techniques due to the difficult visibility in intact specimens. A comparison was then made between the reconstructions, digital photographs, and CT cross-sections of the skull, which enabled the visualization of anatomical peculiarities and exclusivities, such as nasolacrimal-maxillary fenestra, paranasal sinuses, and thin bone architecture, as well as the unique shape of cranial bones, compared to other species that exhibit a unique and genuine phenotype. ABSTRACT wellknown known however scarce studies respect study 1 16 (1 prepared Next CTs (CTs accidents threedimensional dimensional 3D D (3D specimens reconstructions photographs crosssections cross sections skull exclusivities nasolacrimalmaxillary nasolacrimal maxillary fenestra sinuses architecture bones phenotype (

Abstract Introduction: The limited availability of data in Chile on the use of diagnostic images (DI) poses a challenge in the efficient management of resources. Objective: To quantify and characterize the use of DI in hospitalized subjects in Chile for 1 year. Method: Descriptive population based study on the use of DI in Chile during 2019 in hospitalized subjects using an official national database recorded with the diagnosis-related groups (DRG) system. Demographic variables related to hospitalization and derived from the DRG were analyzed. Results: 55.5% of hospital events involved at least one DI (n = 466,306). The most used imaging technique was radiography/X-ray (36.4%), followed by computed tomography (35%). The Magallanes and Aysén regions exhibited the highest DI rates. Hospitalized patients who required some DI had an average of days of hospitalization and mortality rate that were 3.4 and 5.5 times greater than those who did not require DI (p < 0.01). Conclusions: There are important geographical differences in the use of DI in Chile. Our description will facilitate future studies that delve deeper and explore access or socioeconomic differences.

Resumen Introducción: La escasa disponibilidad de datos en Chile sobre el uso de imágenes diagnósticas (ID) plantea un desafío en la gestión eficiente de recursos. Objetivo: Cuantificar y caracterizar el uso de ID en sujetos hospitalizados en Chile durante 1 año. Método: Estudio poblacional descriptivo sobre el uso de ID en Chile durante el año 2019 en sujetos hospitalizados utilizando una base de datos nacional oficial consignada con la herramienta de grupos relacionados a diagnósticos (GRD). Se analizaron variables demográficas, relativas a la hospitalización y derivadas de los GRD. Resultados: El 55,5% de los eventos hospitalarios involucró al menos una ID (n = 466.306). La modalidad de imagen más utilizada fue la radiografía (36,4%), seguida por la tomografía computada (35%). Las regiones de Magallanes y Aysén exhibieron las tasas de ID más altas. Los pacientes hospitalizados que requirieron alguna ID obtuvieron unos promedios de días de hospitalización y letalidad 3,4 y 5,5 veces mayores que los que no requirieron ID (p < 0,01). Conclusiones: Existen importantes diferencias geográficas en la utilización de ID en Chile. Nuestra descripción facilitará la realización de futuros estudios que profundicen y exploren las diferencias en el acceso o socioeconómicas.

ABSTRACT Paracoccidioidomycosis (PCM) is a systemic disease endemic to Latin American countries, with a high impact in terms of morbidity, mortality and costs for the health system if patients progress to advanced stages. This work aimed to collect data published in publications on autochthonous cases of PCM, from the first cases diagnosed in Paraguay, with a description of the historical context and identifying the pioneers in the diagnosis in Paraguay, following a chronological order, to the most recently reported cases. Methodology: search in national libraries and online databases of PCM cases in Paraguay, published in national historical scientific journals and other sources available in print format, and more recent scientific articles available in electronic format, respectively. Results: 479 cases of PCM were identified in publications between the years 1935 and 2023, corresponding to autochthonous cases and whose diagnoses were made in Paraguayan territory. Dr. Juan Boggino and collaborators were responsible for the first diagnoses in the country. The predominant clinical form was chronic. The average age was 45.78 years. The vast majority of patients diagnosed were from the Eastern Region of the country, predominantly male farmers. Conclusion: PCM is an endemic disease in Paraguay. Since the first cases were diagnosed and until today, patients with a severe and disabling course of the disease have been detected, which demonstrates the need to disseminate its knowledge and expand the early diagnostic capacity at the national level. Due to its clinical pleomorphism and its ability to simulate other diseases, it is important to include PCM as a differential diagnosis for patients who present risk factors for the development of the disease.

RESUMEN La Paracoccidioidomicosis (PCM), es una enfermedad sistémica endémica de países de América Latina, con alto impacto en términos de morbilidad, mortalidad y costos para el sistema de salud si los enfermos progresan a sus estadios avanzados. Este trabajo tuvo como objetivo recopilar datos divulgados en publicaciones sobre casos autóctonos de PCM, desde los primeros casos diagnosticados en Paraguay, con una descripción del contexto histórico e identificando a los pioneros en el diagnóstico en Paraguay, siguiendo un orden cronológico, hasta los casos más recientemente informados. Metodología: búsqueda en bibliotecas nacionales y bases de datos online de casos de PCM en Paraguay, publicados en revistas científicas históricas nacionales y otras fuentes disponibles en formato impreso, y artículos científicos más recientes disponibles en formato electrónico, respectivamente. Resultados: Se identificaron 479 casos de PCM en publicaciones entre los años 1935 y 2023, correspondientes a casos autóctonos y cuyos diagnósticos fueron realizados en territorio paraguayo. El Dr. Juan Boggino y colaboradores fueron los responsables de los primeros diagnósticos en el país. La forma clínica predominante fue la crónica. La media de edad de 45,78 años. La gran mayoría de los pacientes diagnosticados fueron oriundos de la Región Oriental del país, predominantemente hombres agricultores. Conclusión: La PCM es una enfermedad endémica del Paraguay, desde los primeros casos diagnosticados y hasta hoy en día, son detectados pacientes con una evolución grave y discapacitante de la enfermedad, lo que demuestra la necesidad de la difusión de su conocimiento y ampliación de la capacidad diagnóstica precoz a nivel nacional. Debido a su pleomorfismo clínico y su capacidad de simular otras enfermedades, es importante incluir a la PCM como diagnóstico diferencial de pacientes que presenten factores de riesgo para el desarrollo de la enfermedad.

Abstract Hygrothermal computer simulations consider transient and simultaneous exchanges of heat and moisture between the building elements and the environment. They are an important tool to support the design and performance assessment of buildings. These simulations require the description of the building element, the environmental conditions to which it is exposed, and the hygrothermal characteristics of the materials that compose it as input data. This paper presents an exploratory analysis of the results of the hygrothermal simulation of a concrete wall varying the hygrothermal characteristics of the material. The internal environmental conditions were obtained using EnergyPlus ® and the hygrothermal simulation was done in WUFI ® Pro, with post-processing in WUFI ® Bio to evaluate the risk of mold occurrence. The hygrothermal behavior of the walls varied significantly with the variation in hygrothermal characteristics of the materials, especially for one type of concrete that had a very different capillary transport function. The results indicate the importance of analyzing hygrothermal characteristics and functions for hygrothermal simulations and the need to experimentally determine such characteristics for Brazilian building materials. environment buildings element exposed data material Pro postprocessing post processing occurrence function

Resumo Simulações computacionais higrotérmicas consideram trocas transientes e simultâneas de calor e umidade entre os elementos construtivos e o ambiente, sendo uma ferramenta importante de apoio ao projeto e à avaliação de desempenho de edifícios. Essas simulações requerem como dados de entrada a descrição do elemento construtivo, as condições ambientais às quais ele está exposto e as características higrotérmicas dos materiais. Este artigo apresenta uma análise exploratória dos resultados da simulação higrotérmica de uma parede de concreto variando-se as características higrotérmicas do material. As condições ambientais internas foram obtidas utilizando o EnergyPlus™ e a simulação higrotérmica foi feita no WUFI® Pro, com pós-processamento no WUFI® Bio para avaliar o risco de ocorrência de fungos emboloradores. Houve diferenças significativas no comportamento higrotérmico das paredes em função da variação das características higrotérmicas dos materiais, sobretudo para o tipo de concreto cuja função de transporte capilar mostrou-se diferente dos demais. Os resultados indicam a importância de analisar as características e funções higrotérmicas para simulações higrotérmicas e a necessidade de sua determinação experimental para os materiais de construção brasileiros. ambiente edifícios construtivo variandose variando se material EnergyPlus WUFI Pro pósprocessamento pós processamento emboloradores mostrouse mostrou demais brasileiros

Abstract What and how did the writers of the first centuries of the Italian language read? Thanks to the influence of what readings did you compose your works? In the case of Boccaccio and Petrarch, the answer to this question was found in the books they owned and in which in many cases they made notes. Of Dante, on the other hand, we do not possess either the books or a single word written in his handwriting: we can only imagine the appearance of his handwriting thanks to the description that Leonardi Bruni left of it, probably based on a Dantesque autograph, now lost. Given this lack of data, Dante’s sole mention of his own training is of great importance, that is, the passage from the Convivio in which he narrates that he undertook philosophical studies immediately after the death of Beatrix, prompted by the reading of the Consolatio Philosophiae of Boethius to go for thirty months “to the schools of the religious and to the disputes of the philosophers” (Conv. II, XII, 1-7). The schools frequented by the Poet can be identified with the conventual Studia of Florence, that is, the Franciscan of Santa Croce, the Dominican of Santa Maria Novella and the Augustinian of Santo Spirito, unique places of conservation of books and education, in addition to the teaching by isolated private teachers like Brunetto Latini. Among these institutions, home to lively cultural activity, philosophical disputes and study, the historical data attributable to Dante favors Santa Croce, whose books (today preserved mainly in the Biblioteca Medicea Laurenciana and in the National Central Library of Florence) document the physiognomy in which the texts he read were offered to his eyes and were models of his works. This contribution traces a journey through the precious bibliographic heritage of the Franciscan Studium, with the aim of reconstructing and documenting the circulation of Dante’s works in his homeland and the Florentine context in which the poet’s extraordinary cultural formation took place.

Resumen ¿Qué y cómo leían los escritores de los primeros siglos de la lengua italiana? ¿Bajo la influencia de qué lecturas compusieron sus obras? En el caso de Boccaccio y Petrarca, la respuesta a esta pregunta se encontró en los libros que poseían y en los que, en muchos casos, hicieron anotaciones. De Dante, en cambio, no poseemos ni los libros ni una sola palabra escrita de su puño y letra: sólo podemos imaginar el aspecto de su caligrafía gracias a la descripción que de ella dejó Leonardi Bruni, probablemente basada en un autógrafo dantesco, hoy perdido. Dada esta ausencia de datos, cobra gran importancia la única mención de Dante a su propia formación, es decir, el pasaje del Convivio en el que narra que emprendió estudios filosóficos inmediatamente después de la muerte de Beatriz, impulsado por la lectura de la Consolatio Philosophiae de Boecio para ir durante treinta meses “a las escuelas de los religiosos y a las disputas de los filósofos” (Conv. II, XII, 1-7). Las escuelas frecuentadas por el Poeta se pueden identificar con los Studia conventuales de Florencia, es decir, la franciscana de Santa Croce, la dominicana de Santa Maria Novella y la agustina de Santo Spirito, únicos lugares de conservación de libros y educación, además de la enseñanza privada de profesores aislados como Brunetto Latini. Entre estas instituciones, sedes de una animada actividad cultural, de disputas filosóficas y de estudio, los datos históricos atribuibles a Dante favorecen a Santa Croce, cuyos libros (hoy conservados principalmente en la Biblioteca Medicea Laurenciana y en la Biblioteca Nacional Central de Florencia) documentan los textos que leía y eran modelos de sus obras. Esta contribución traza un recorrido por el preciado patrimonio bibliográfico del Studium franciscano, con el objetivo de reconstruir y documentar la circulación de las obras de Dante en su patria y el contexto florentino en el que tuvo lugar la extraordinaria formación cultural del poeta.

Resumen En este artículo se sustenta que el servicio de educación indígena de Baja California, el cual opera desde hace más de 40 años, posee características que lo distinguen de otros similares que se desarrollan en diversos estados de la república mexicana. En este caso, su crecimiento está articulado a los procesos de migración interna, cuya diversidad cultural y lingüística está presente en las aulas. Para lograr una descripción pormenorizada de sus principales rasgos, se realizó un análisis estadístico con información obtenida de las bases de datos de la Coordinación Estatal de Educación Indígena, de la prueba Planea, de la estadística educativa del Formato 911, así como de entrevistas aplicadas a informantes clave. Los resultados permiten identificar el tipo de organización de los centros escolares, los perfiles académico y lingüístico del profesorado y del alumnado, así como sus especificidades y retos para continuar brindando el servicio.

Abstract In this article it is founded that the indigenous education service in Baja California, which has been operating for more than forty years, has acquired characteristics that distinguish it from other similar services that operate in different states of the Mexican Republic. In this case, its growth is linked to internal migration processes. Hence, the cultural and linguistic diversity in the classrooms. In order to achieve a detailed description of their characteristics, a statistical analysis was carried out with information from the databases of the Coordinación Estatal de Educación Indígena, the PLANEA test, and the educational statistics of the Formato 911, as well as interviews with key informants. The results allow to identify the type of organization of the schools and the academic and linguistic profiles of teachers and students, as well as their specificities and challenges to continue providing the service.

RESUMEN Algunos autores estamos interesados por cierto ámbito o enfoque de la actividad filosófica usualmente denominado "filosofía experimental". El objetivo fundamental de este artículo es analizar los rasgos principales que caracterizan a dicha especialidad, conforme al sentido en que comenzó a utilizarse esa etiqueta. Entre otras consideraciones, se constatará que la denominación "filosofía experimental" es parcialmente acertada, pero también parcialmente equívoca debido a dos razones. Una razón queda de manifiesto en discusiones contemporáneas que localizan antecedentes de ese enfoque en conexiones entre la filosofía y las ciencias empíricas a través de los siglos. La segunda razón tiene mayor importancia; para identificarla será conveniente evaluar las funciones de la experimentación, tanto en las ciencias empíricas como en la filosofía. De especial relevancia será reflexionar sobre cierto tipo de experimentos: los experimentos mentales.

ABSTRACT Some of us are interested in a certain field or approach to philosophical activity usually called "experimental philosophy". The primary goal of this article is to analyze the main features that characterize this specialty, according to the sense in which the label began to be used. Among other considerations, we will see that the description "experimental philosophy" is partially correct, but also partially wrong, due to two reasons. The first can be tracked in contemporary discussions that locate antecedents of that approach in connections between philosophy and the empirical sciences through the centuries. To identify the second, more important reason, it will be convenient to evaluate the functions of experimentation, both in the empirical sciences and in philosophy. To reflect on certain types of experiments, mental experiments, will be crucially relevant.

ABSTRACT Introduction: The introduction of Single-Port (SP) platform opened the field to new surgical options, allowing to perform major urological robot-assisted procedures extraperitoneally and with a supine patient positioning (1–3). Nevertheless, a comprehensive description of different supine access options is still lacking (4–6). In this light, we provided a step-by-step guide of SP extraperitoneal supine access options also exploring preliminary surgical outcomes. Materials and methods: Transvesical access was performed by a transversal incision 3cm above the pubic bone, after the anterior abdominal sheet incision, the bladder was insufflated with a flexible cystoscope and the detrusor muscle was incised at the level of the bladder dome. Similarly, the extraperitoneal access was carried out with a 4cm incision above the pubic bone, once visualized the preperitoneal space the prevesical fat was gently spread. The Low Anterior Access was performed with a 3cm incision at the McBurney point, the abdominal muscles were then spread. A gentle dissection was used laterally to develop the retroperitoneal space. Results: Overall, sixteen different procedures were performed with supine extraperitoneal access on 623 consecutive patients. No intraoperative conversions occurred. The median access time was 16 (IQR 12-21), 11 (IQR 7-14) and 14 (IQR 10-18) minutes in case of transvesical, extraperitoneal and low anterior access, respectively. Notably, 81.5 % of patients were discharged on the same day with a postoperative opioid free rate of 73%. Conclusion: The Atlas provides a comprehensive step-by-step guide to successfully perform all major urological SP procedures extraperitoneally and with supine patient positioning. Introduction SinglePort Single Port (SP robotassisted robot assisted 1–3. 13 1–3 . 1 3 (1–3) Nevertheless 4–6. 46 4–6 4 6 (4–6) light stepbystep step outcomes methods cm bone dome Similarly spread point Results Overall 62 occurred IQR 1221, 1221 12 21 , 12-21) 714 7 7-14 1018 10 18 10-18 transvesical respectively Notably 815 81 5 81. 73 73% Conclusion 1– (1–3 4– (4–6 122 2 12-21 71 7-1 101 10-1 8 (1– (4– 12-2 7- 10- (1 (4 12- (

Abstract: In architecture, microorganisms can act as heroes or villains. However, research on microorganisms has been delegated to engineering sciences and is usually conducted in parallel with architecture. This study analyzes scientific advances in biomaterials, including microorganisms that benefit materials and microorganisms that degrade buildings. The methodology consisted of a literature review, followed by a classification and description of the microorganisms to facilitate the analysis of the findings. The results revealed that some microorganisms provide materials with positive characteristics, such as greater durability, self-repair, increased compression and absorption, and most importantly, environmental sustainability. During destructive processes, microorganisms primarily affect heritage buildings because of their destructive properties. The biodegradation of buildings can be slowed, delayed, or inhibited by microorganisms; therefore, this analysis can provide an opportunity to advance materials research.

Resumen: En arquitectura, los microorganismos tienen la doble capacidad de comportarse como héroes o villanos. Sin embargo, la investigación sobre microorganismos se ha delegado a las ciencias de la ingeniería y se suelen llevar de forma paralela a la arquitectura. Este artículo hace una revisión documental y un análisis de los avances científicos más recientes en biomateriales, incluyendo los microorganismos que benefician y los microorganismos que degradan las construcciones. La metodología consiste en una revisión documental en bases de datos en inglés y español, para sistematizar hallazgos y hacer una clasificación de microorganismos. Los resultados revelan que algunos microorganismos brindan a los materiales características positivas como mayor durabilidad, autorreparación, incremento a la compresión o absorción, pero sobre todo favorecen la sostenibilidad ambiental. En los procesos destructivos, los microorganismos afectan principalmente las edificaciones patrimoniales por sus materiales y temporalidad, lo cual representa un desafío para la ciencia de los materiales ya que algunos microorganismos o sus compuestos pueden retardar, retrasar o inhibir el biodeterioro de los edificios.

Resumen La incorporación de nuevas tecnologías, como ultrasonido, J-Plasma (plasma de helio) y el Microaire (vibroliposucción), ha facilitado los procedimientos de lipoescultura consiguiendo una mayor satisfacción del paciente. Los beneficios de estas tecnologías se acompañan de bajas complicaciones reportadas; el presente caso constituye la cuarta descripción de neumomediastino secundario a la utilización de Renuvion® (J-Plasma) posterior a la extracción de grasa en brazos y muslos por medio de liposucción; esta infrecuente complicación se debe considerar diagnóstico diferencial en el estudio de presentación clínica de disnea y enfisema subcutáneo durante el posoperatorio.

Abstract The incorporation of new technologies such as ultrasound, J-Plasma (helium plasma) and MicroAire (power assited liposuction) has facilitated liposculpture procedures, resulting in greater patient satisfaction. The benefits of these technologies are accompanied by low reported complications; this case is the fourth description of pneumomediastinum secondary to the use of Renuvion® (J-Plasma) after liposuction for fat removal in the arms and thighs. This rare complication should be considered as part of the differential diagnosis during the study of clinical dyspnea and subcutaneous emphysema in the postoperative period.

Resumo: Este estudo corresponde a uma investigação-ação e tem como objetivo examinar a contribuição da estratégia de descrição de imagens implementada por meio do aplicativo TikTok® para melhorar a precisão oral de um grupo de cinco estudantes do primeiro ano de graduação do curso de Língua Inglesa I, do programa de Tradução e Interpretação em uma universidade chilena. Foi utilizada amostragem intencional, uma vez que os participantes foram escolhidos por apresentarem dificuldades para se expressar oralmente em inglês. A coleta de dados incluiu pré e pós-avaliações orais, bem como grupo focal e autoavaliação, de acordo com os objetivos da investigação. A intervenção consistiu em seis sessões nas quais os participantes praticaram diferentes estruturas gramaticais e vocabulário específico relacionado à descrição de imagens. Os resultados obtidos demonstraram que a utilização da técnica de descrição de imagens implementada através de vídeos carregados na aplicação TikTok® foi benéfica para os estudantes, pois permitiu-lhes melhorar a sua precisão oral tanto no uso adequado da gramática como na gestão do vocabulário. Além disso, as opiniões dos participantes no grupo focal e na autoavaliação quanto à utilização do TikTok® em contexto educativo foram positivas, destacando a sua utilidade e facilidade de utilização.

Abstract: Este estudio corresponde a una investigación acción y tiene como propósito examinar el aporte de la estrategia de descripción de imágenes implementada mediante la aplicación TikTok® para mejorar la precisión oral de un grupo de cinco estudiantes de primer año de pregrado del curso de Lengua Inglesa I, del programa de Traducción e Interpretación de una universidad chilena. Se utilizó un muestreo intencional, ya que los participantes fueron elegidos por tener dificultades para expresarse oralmente en inglés. La recopilación de datos incluyó evaluaciones orales previas y posteriores, así como un grupo focal y una autoevaluación, en concordancia con los objetivos de la investigación. La intervención constó de seis sesiones en las que los participantes practicaron diferentes estructuras gramaticales y vocabulario específico relacionado con la descripción de imágenes. Los resultados obtenidos mostraron que el uso de la técnica de descripción de imágenes implementada a través de vídeos subidos a la aplicación TikTok® fue beneficioso para los estudiantes, ya que les permitió mejorar su precisión oral tanto en el uso adecuado de la gramática como en el manejo del vocabulario. Además, las opiniones de los participantes en el grupo focal y en la autoevaluación en cuanto al uso de TikTok® en un contexto educativo fueron positivas, y destacaron su utilidad y facilidad de uso.

Abstract This research analyzes the system of reference in narratives from the Wixárika language. The language displays 8 strategies for identifying entities and their functions, 6 of which are common at a typological level, while the remaining two distinguish Wixárika from other Southern Uto-Aztecan languages. These two strategies include the suffixes of referential continuity and possessive pronouns which encode the same or different subject. This research provides a detailed description of these resources, including their frequency and a preliminary observation of the grammaticalization process of the suffixes of referential continuity. Overall, the language exhibits patterns that differ from those observed in previous literature.

Resumen El presente estudio analiza el sistema de seguimiento de referencia en narraciones del wixárika. La lengua dispone de 8 recursos para identificar a las entidades referenciales y sus funciones, de los cuales 6 son comunes a nivel tipológico. Los dos recursos restantes que distinguen al wixárika de otras lenguas yutoaztecas sureñas son los sufijos de seguimiento de referencia y los pronombres posesivos que codifican mismo o diferente sujeto. Además de describir cada uno de estos recursos, se reporta su frecuencia y observaciones preliminares sobre el proceso de gramaticalización de los sufijos de seguimiento de referencia. Estos hallazgos muestran que el wixárika presenta patrones diferentes a los observados en estudios previos.