Abstract (Introduction): Bycatch and discards are a socio-environmental concern that threatens the sustainability of marine life and fishing grounds. Approaches to this problem have focused on biological and/or ecological aspects. We considered it necessary to explore the problem from the social dimension and for this purpose we explored social representations. (Objective): The aim of this study is to explore the social representations of bycatch and discards in a group of businessmen and workers in the capture stage of the Argentine industrial fishing activity. We ask how they evaluate bycatch and fishing discards, what are their causes and if they observe possible solutions. (Methodology): Within the framework of a project of the Federal Fishing Council, we conducted focus groups with businessmen, business chambers, SOMU workers and captains of the industrial fishing activity. (Results): The results of the focus groups conducted in 2021 reveal three main causes of this problem. First, the lack of reliable data on actual discard levels raises concerns about sustainability and overfishing. Second, the low utilization of selectivity devices is attributed to their operational inefficiency and possible labour barriers. Finally, economic and organizational pressures, such as company profitability and workers’ salaries, justify the discard of non-target species, exacerbating the problem. (Conclusions): The work contributes to an understanding of the main reasons for bycatch and discards, which is essential to advance solutions. We understand that solutions are not simple and involve a sincere debate among stakeholders.

Resumen (Introducción): Las capturas incidentales y los descartes pesqueros son una preocupación socioambiental que amenaza la sostenibilidad de la vida marina y de los caladeros. Los abordajes a esta problemática estuvieron centrados en aspectos biológicos y ecológicos. Consideramos necesario explorar la problemática desde la dimensión social y para ello, exploramos las representaciones sociales. (Objetivo): El objetivo de este estudio fue explorar las representaciones sobre capturas incidentales y descartes pesqueros en un grupo de empresarios y trabajadores de la etapa de captura de la actividad pesquera industrial argentina, específicamente, cómo evalúan este problema, sus causas y posibles soluciones. (Metodología): En el marco de un proyecto del Consejo Federal Pesquero, se realizaron grupos focales con seis cámaras empresariales y personal jerárquico de empresas asociadas, así como trabajadores del SOMU y capitanes que operan en alta mar. (Resultados): Los resultados de los grupos focales realizados en 2021 revelaron tres principales causas de dicha problemática. Primero, la falta de datos confiables sobre los niveles reales de descarte genera preocupaciones sobre la sostenibilidad y la sobreexplotación. Segundo, la escasa utilización de dispositivos de selectividad se atribuye a su ineficacia operativa y a posibles barreras laborales. Finalmente, las presiones económicas y organizacionales, como la rentabilidad de las empresas y los salarios de los trabajadores, justifican el descarte, exacerbando el problema. (Conclusiones): El trabajo aporta a un entendimiento sobre las razones de la captura incidental y los descarte, esencial para avanzar en soluciones. Entendemos que las soluciones no son simples e implican un sincero debate entre actores.

Resumen Este artículo investiga la gramática institucional de la protección de datos y de la privacidad en Brasil. Adoptando la perspectiva analítica del Intitutional Grammar Tool (IGT), deconstruimos los enunciados institucionales de los decretos reglamentarios de la Ley General de Protección de Datos de los estados brasileros, con el fin de clasificar los diferentes elementos gramaticales que informaron las estrategias estaduales de protección y gobernanza de datos. Examinamos la construcción de los conceptos de protección de datos, gobernanza de datos y privacidad, así como la construcción institucional de la protección de datos en Brasil. El estudio tiene un abordaje empírico, con el fin de responder a las siguientes cuestiones: ¿cuál es el diseño institucional de las estrategias adoptadas por los estados, en el contexto de la federación, para la protección de datos personales y de la privacidad de los ciudadanos? ¿cuáles son las implicaciones de ese diseño para la efectividad de la protección de datos en Brasil? El artículo concluye que las estrategias de protección de datos formuladas en los estados tienen más un enfoque de control burocrático de tratamiento de datos que propiamente la implementación de derechos emergentes de ciudadanía.

Resumo Este artigo investiga a gramática institucional da proteção de dados e da privacidade no Brasil. Adotando a lente analítica do Intitutional Grammar Tool (IGT), desconstruímos os enunciados institucionais dos decretos regulamentadores da Lei Geral de Proteção de Dados dos estados brasileiros, de forma a classificar os diferentes elementos gramaticais que informam as estratégias estaduais de proteção e governança de dados. Examinamos nesse artigo a construção dos conceitos de proteção de dados, governança de dados e privacidade, assim como a construção institucional da proteção de dados no Brasil. O estudo tem um viés empírico, de maneira a responder às seguintes questões: qual o desenho institucional das estratégias adotadas pelos estados, no contexto da federação, para a proteção de dados pessoais e da privacidade dos cidadãos? Quais as implicações desse desenho para a efetividade da proteção de dados no Brasil? O artigo conclui que as estratégias de proteção de dados formuladas nos estados têm mais o viés de controle burocrático do tratamento de dados do que propriamente a efetivação de direitos emergentes de cidadania.

Abstract This article investigates the institutional grammar of data protection and privacy in Brazil. By adopting the analytical lens of the Institutional Grammar Tool (IGT), it deconstructs the institutional statements within the regulatory decrees of the General Data Protection Law (LGPD) in Brazilian states, classifying the different grammatical elements that inform state-level strategies for data protection and governance. It examines how the concepts of data protection, data governance, and privacy are formulated, as well as the institutional construction of data protection in Brazil. By taking an empirical approach, it aims to address the following questions: What is the institutional design of the strategies adopted by Brazilian states, within the federation, to protect personal data and citizens’ privacy? What are the implications of this design on how effective data protection is in Brazil? The article concludes that the data protection strategies formulated by the states lean more toward bureaucratic control of data processing than the actual realization of emerging citizenship rights.

Résumé Cet article explore la grammaire institutionnelle de la protection des données et de la vie privée au Brésil. En adoptant la perspective analytique de l’Institutional Grammar Tool (IGT), nous déconstruisons les énoncés institutionnels des décrets réglementaires de la Loi Générale sur la Protection des Données des états brésiliens, afin de classifier les différents éléments grammaticaux informant les stratégies étatiques de protection et de gouvernance des données. Nous examinons dans cet article la construction des concepts de protection des données, de gouvernance des données et de vie privée, ainsi que la construction institutionnelle de la protection des données au Brésil. L’étude a une orientation empirique afin de répondre aux questions suivantes: quel est le dessin institutionnel des stratégies adoptées par les états, dans le contexte de la fédération, pour la protection des données personnelles et de la vie privée des citoyens? Quelles sont les implications de ce dessin pour l’efficacité de la protection des données au Brésil? L’article conclut que les stratégies de protection des données formulées au niveau des états sont davantage orientées vers le contrôle bureaucratique du traitement des données que vers la réalisation effective des droits émergents de la citoyenneté.

Parthenolide (PTN) is a secondary metabolite of the plant Tanacetum parthenium (L.) Schulz Bip. and is considered the chemical marker of this species. This sesquiterpene lactone (germacrene skeleton) has been described as responsible for the biological activity of the leaf extract. In addition, several studies in the literature have demonstrated its antiparasitic and antineoplastic activity. However, there is a need for knowledge of other safety parameters, such as pharmacokinetic, pharmacodynamic and toxicity evaluations. Therefore, in this investigation, the in vitro metabolism of parthenolide was performed with rat liver microsomes and biomimetic metabolism (such as cytochrome P-450 system) using organometallic catalysts. The biomimetic procedure was validated since the major compound of biomimetic oxidative reaction with meta-chloroperbenzoic acid catalyzed by metalloporphyrin 5,10,15,20-tetrakis(pentafluorophenyl)-porphyrin iron(III) chloride was also observed with rat liver microsomes. Previous chemoenzymatic synthesis studies of PTN afforded the same epoxide formation, this major oxidative compound was isolated and fully characterized as (1 R,10R)-epoxyparthenolide based on experimental and theoretical calculations of infrared (IR) and vibrational circular dichroism (VCD) data at the B3PW91/6-311G. Furthermore, for the first time, this metabolite was evaluated for trypanocidal and leishmanicidal activity. The mean inhibitory concentration (IC50) values were lower for PTN than its metabolite and showed significant cytotoxic effects for both parasites. This finding holds promise for addressing neglected diseases.

Diaporthe phaseolorum, an endophyte isolated from Combretum lanceolatum, has exhibited diverse biological activities including antimicrobial, leishmanicidal, antitumoral, and herbicidal properties. Regardless of these activities, there remains limited research on its chemical constituents. Therefore, this study aimed to investigate the metabolome of D. phaseolorum employing mass spectrometry data dereplication through molecular networking and MolNetEnhancer tools. Twenty two molecular families were annotated, including prenol lipids, benzenoids, organoheterocyclic compounds, and nucleosides. Among the 41 nodes annotated, 36 metabolites were confirmed via spectral references, including alismol, farnesol, linoleic acid, tyramine, N-acetyl-tyramine, 5-methoxy-1H-indole-3-carbaldehyde, 6-pentyl-2H-pyran-2-one, and adenosine. Further node annotation was achieved through MolNetEnhancer, resulting in the classification of an additional 68 nodes into various molecular families. Consequently, this study represents a significant contribution to the identification of the D. phaseolorum metabolome, highlighting its secondary metabolites and providing valuable chemical insights to elucidate its demonstrated biological activities.

The study of atomic spectroscopy has a profound relationship with quantum mechanics and its comprehension. Since Bohr’s success with a theory for the atom, it has been established that spectrum lines originate from transitions between different states. Moreover, the analysis of complex spectra reveals that there are groups of spectral lines that compose what is called a multiplet. To rationalize the multiplet structure, we need models to characterize and label the quantum states. The characterization of the atomic states is a common subject in classes of physical chemistry and inorganic chemistry, and there are basically two approaches to infer and label the energy states: (i) the LS coupling scheme and (ii) the jj coupling scheme. Usually, only the LS coupling is presented, and this ends up omitting its underlying assumptions. Here, we present a survey of both approaches, highlighting their premises and their adequacy towards different groups of the periodic table, ions, and excited states configurations. We show that by using benchmark data together with the Landé interval rule, the appropriate use of the jj coupling to understand the atomic spectra of heavier atoms is easily conveyed.

ABSTRACT Quantifying the impact of driving factors on crop water productivity (WP) is essential for efficient agricultural water use. To date, few studies have investigated the influence of management and environmental factors on sugarcane WP at the mill scale. This study aimed to assess the contributions of management practice factors, weather variables, and soil management zones (SMZs) on on-farm sugarcane WP in a single mill in the southern region of Brazil. An extensive on-farm database of commercial sugarcane field plots was used with a weather database to estimate evapotranspiration and water-limited potential yield (Yw). This was achieved by employing a crop sugarcane model to calculate actual water productivity (WPa) and attainable water productivity (WPw). The results demonstrated an inverse relationship between management practices and WPa, while harvest date and vinasse positively impacted on WPa. The Yw, actual yield (Ya), actual evapotranspiration (ETa) or crop evapotranspiration (ETc), and WPa varied according to the SMZ. The lowest WPa values were observed in the worst soils. The analysis revealed that weather variables collectively accounted for 46.2 % of WPa variability, management practice factors accounted for 40.5 %, and SMZs contributed 13.3 % of WPa variability. Despite weather variables being the primary source of WPa variability, management practice factors still played a key role in WPa variability. (WP use scale (SMZs onfarm farm Brazil waterlimited limited Yw. Yw . (Yw) (WPa WPw. WPw (WPw) Ya, Ya , (Ya) ETa (ETa ETc, ETc (ETc) SMZ soils 462 46 2 46. variability 405 40 5 40. 133 13 3 13. (Yw (WPw (Ya (ETc 4 1

ABSTRACT To ensure the sustainability of agriculture and the production of safe food, supplementary irrigation is required for crops that are primarily rainfed, particularly in arid conditions. This study aimed to determine the water stress response of safflower (Carthamus tinctorius L.) under limited water conditions and to establish the crop water stress index (CWSI) as a basis for crop-based irrigation scheduling. Irrigation applications were conducted using the line-source sprinkler irrigation method to create three constraints (35, 75, and 100 % of the water requirement) and a rainfed condition (control plot) under different crop growth periods. The main plots consisted of three growth periods of safflower and only one supplementary irrigation during the vegetative, flowering, and ripening periods. The highest yield was obtained at 3.06 and 3.42 t ha–1 for 2019 and 2021, respectively, in the plot that was irrigated in each period during the growing season. The irrigation water (I) and water use efficiency (WUE) were 0.42 and 0.51 kg m–3 in the first year, and 0.47 and 0.59 kg m–3 in the second year, respectively, for the subject fully irrigated throughout the season. The upper base value, which can be utilized in calculations of the CWSI, was determined to be approximately 14.50. The lower base equation was obtained as Y = −4.9428 (VPD) + 19.121 at a statistical significance level of 1 % where Y is yield and VPD is vapor pressure deficit. The CWSI values calculated for each treatment ranged between −0.25 and 1.45. The threshold value at which irrigation should commence was determined to be 0.63, and it will serve as a valuable reference data source for irrigation scheduling. food Carthamus L. L (CWSI cropbased based scheduling linesource line 35, 35 (35 75 10 requirement control vegetative flowering 306 3 06 3.0 342 42 3.4 ha1 ha ha– 201 2021 respectively season I (I WUE (WUE 042 0 0.4 051 51 0.5 m3 m m– year 047 47 059 59 1450 14 50 14.50 49428 4 9428 −4.942 (VPD 19121 19 121 19.12 deficit 025 25 −0.2 145 45 1.45 063 63 0.63 (3 7 30 3. 34 20 202 04 0. 05 5 14.5 4942 942 −4.94 1912 12 19.1 02 2 −0. 1.4 6 0.6 ( 14. 494 94 −4.9 191 19. −0 1. 49 9 −4. − −4

ABSTRACT Nitrogen (N) is essential to the fertilization of coffee. The fertilizer most used to meet this demand is urea, although it has high rates of N loss due mainly to ammonia volatilization. To reduce this loss, fertilizers with increased efficiency have emerged. Thus, the aim was to select the most appropriate nonlinear regression model to describe N loss attributable to ammonia volatilization in slow- and controlled-release fertilizers applied to coffee plants and to compare the different fertilizers based on the parameters of the selected model. The data studied are controlled-release fertilizers: urea + sulfur + polymer (U+S+P), urea + plastic resin (U+PR), urea + polymer insoluble in water (U+PIW) and slow-release fertilizer: urea formaldehyde (UF) applied to coffee. The Gompertz, Brody, and von Bertalanffy Logistics models were fit by the least squares method. The goodness of fit was assessed using the adjusted coefficient of determination, mean absolute deviation, and Akaike's information criterion. The von Bertalanffy model was the most appropriate for describing the data in most cases. After selecting the best model for the means, the parameters of the von Bertalanffy model were estimated again for each repetition of treatments. With the repetitions of the parameter estimates of these models, the F test of analysis of variance (ANOVA) and Tukey's test were applied. In the F test, p < 0.05 for all parameters. In the Tukey's test, the UF fertilizer reached the asymptote more quickly and presented a lower accumulated loss of N in the coffee tree. The fertilizers U+S+P and U+PIW have later inflection points (IP). (N emerged Thus slow controlledrelease controlled release U+S+P, USP , U S P (U+S+P) U+PR, UPR U+PR PR (U+PR) UPIW PIW (U+PIW slowrelease (UF Gompertz Brody method determination deviation Akaikes Akaike s criterion cases means treatments ANOVA (ANOVA Tukeys Tukey 005 0 05 0.0 tree IP. IP . (IP) (U+S+P (U+PR 00 0. (IP

RESUMO Em regiões com baixa disponibilidade hídrica é de grande importância um planejamento mais detalhado sobre o uso de recursos hídricos. A utilização de modelos climáticos destinados às previsões de curto e médio prazo se apresenta como uma estratégia importante para se obter informações antecipadas acerca da demanda hídrica de culturas e do regime hídrico de determinada bacia. Objetivou-se, neste estudo, avaliar o desempenho das previsões climáticas sazonais e sua aplicabilidade na estimativa da demanda de irrigação. Para tanto, utilizou-se o Modelo de Simulação de Estratégias de Irrigação e dados de previsão climática derivados do modelo Eta. Para análise das simulações, foi utilizado um conjunto de cinco membros (dias 13, 14, 15, 16 e 17) de previsão sazonal de precipitação e evapotranspiração de referência para cada mês entre o período de 2001 a 2012. O espalhamento para a evapotranspiração de referência demonstrou que o modelo não foi capaz de reproduzir o comportamento desta variável durante o período seco. Comparação entre previsões com os meses de antecedência não demonstraram diferenças significativas entre previsões da precipitação e da evapotranspiração de referência. Contudo, os resultados obtidos para as previsões com um mês de antecedência apresentaram melhor desempenho. hídricos bacia Objetivouse, Objetivouse Objetivou se, Objetivou-se estudo irrigação tanto utilizouse utilizou Eta simulações dias 13 14 15 1 17 200 2012 seco Contudo 20 201 2

ABSTRACT In regions with water shortages, detailed planning on water resource use is essential. The use of climate models for short- and medium-range forecasts is an important strategy for obtaining early information on the water requirements of crops and the water regime of a particular basin. This study aimed to assess the performance of seasonal climate forecasts and their applicability in estimating irrigation needs. To that end, the Simulation Model for Irrigation Strategies and climate forecast data derived from the Eta model were used. To analyze simulations, five members (days 13, 14, 15, 16 and 17) of the seasonal forecasts of rainfall and reference evapotranspiration for every month between 2001 and 2012 were used. The spread for reference evapotranspiration demonstrated that the model was unable to reproduce the behavior of this variable during the dry period. Comparison between forecasts months in advance showed no significant differences between the rainfall and the reference evapotranspiration forecasts. However, the results obtained for a one-month lead-time forecast exhibited superior performance. shortages essential short mediumrange medium range basin needs end used simulations days 13 14 15 1 17 200 201 period However onemonth one leadtime lead time 20 2

ABSTRACT Purpose: To describe the ophthalmological findings of dry eye disease and its relation to the quality of life of COVID-19 survivors. Methods: COVID-19 survivors who had previously been hospitalized at Hospital das Clínicas de Ribeirão Preto complex underwent an ophthalmological evaluation, which included a dry eye disease questionnaire, break-up time, fluorescein staining, and Schirmer test. We collected the presenting and best-corrected visual acuity, sociodemographic data, personal medical history, and scores from a self-reported quality of life questionnaire (WHOQOL-bref). According to the severity of the acute phase of the disease, the patients were classified into mild-to-moderate, severe, and critical groups. Results: Ninety-five patients (190 eyes) were evaluated 100 ± 44 days after the onset of COVID-19 symptoms. Of these, 83 patients (87.3%) completed the WHOQOL-bref questionnaire. Ten patients (12.0%) had mild-to-moderate COVID-19, 41 (49.4%) had severe COVID-19, and 32 (38.6%) had critical COVID-19. The median best-corrected visual acuity was logMAR 0 (0-1). Approximately 26.3% patients had a history of dry eye disease or severe dry eye symptoms (frequent or constant ocular dryness and irritation). There was an association between the proportion of patients with dry eye disease and the quality of life (p=0.014) and health (p=0.001). Furthermore, there was a significant trend between the proportion of patients with dry eye disease and how they rated their health and quality of life (p=0.0004 and 0.0027, respectively. Conclusions: There is a significant negative correlation between the proportion of patients with dry eye disease and their self-reported quality of life. Purpose COVID19 COVID 19 COVID-1 Methods evaluation breakup break up time staining test bestcorrected best corrected data selfreported self reported WHOQOLbref. WHOQOLbref WHOQOL bref . (WHOQOL-bref) mildtomoderate, mildtomoderate mild moderate, moderate groups Results Ninetyfive Ninety five 190 (19 eyes 10 4 these 8 87.3% 873 87 3 (87.3% 12.0% 120 12 (12.0% COVID19, 19, 49.4% 494 49 (49.4% 38.6% 386 38 6 (38.6% COVID19. 19. 01. 01 1 (0-1) 263 26 26.3 frequent irritation. irritation irritation) p=0.014 p0014 p 014 (p=0.014 p=0.001. p0001 p=0.001 001 (p=0.001) Furthermore p=0.0004 p00004 0004 (p=0.000 00027 0027 0.0027 respectively Conclusions COVID1 COVID- (WHOQOL-bref (1 87.3 (87.3 12.0 (12.0 49.4 (49.4 38.6 (38.6 (0-1 2 26. p=0.01 p001 (p=0.01 p000 p=0.00 00 (p=0.001 p=0.000 p0000 000 (p=0.00 0002 002 0.002 ( 87. (87. 12. (12. 49. (49. 38. (38. (0- p=0.0 p00 (p=0.0 0.00 (87 (12 (49 (38 (0 p=0. p0 (p=0. 0.0 (8 (4 (3 p=0 (p=0 0. p= (p= (p

ABSTRACT Purpose: This study aimed to characterize retinitis pigmentosa associated with the eyes shut homolog gene, which causes hereditary retinal degeneration. Methods: The anatomical and functional findings of retinitis pigmentosa in patients with variants of the eyes shut homolog gene were characterized and compared using multimodal imaging and genetic analysis of the variants. Clinical data such as visual acuity, lens status, and refraction were obtained from medical records. Patients underwent an ophthalmic examination, including static visual field, microperimetry, optical coherence tomography, fundus autofluorescence, and fundus photography. Results: Twenty-two patients were included in the study. Several anatomical and functional characteristics of retinitis pigmentosa-eyes shut homolog were identified, including the presence of cataracts, cystoid macular edema, epiretinal membrane, and a tubular visual field. Genetic results revealed 26 distinct variants in the cohort, with 7 novel variants not previously documented or reported in the scientific literature or databases. Conclusion: The findings demonstrate that eyes shut homolog-retinitis pigmentosa manifests in specific patterns, starting in adolescence with mild progression and advancing with age. The integration of multimodal imaging and genetic analysis has provided a detailed understanding of the anatomical and functional features of retinitis pigmentosa-eyes shut homolog. Seven novel variants of the eyes shut homolog gene have been identified. These findings enhance the understanding of eyes shut homolog-related retinitis pigmentosa characteristics of by detailing the spectrum of mutations in this gene within the Brazilian population. Purpose degeneration Methods acuity status records examination field microperimetry tomography autofluorescence photography Results Twentytwo Twenty two pigmentosaeyes identified cataracts edema membrane 2 cohort databases Conclusion homologretinitis patterns age homologrelated related population

ABSTRACT Purpose: To determine the impact of prophylactic intracameral cefuroxime administration on the post-cataract surgery endophthalmitis rates and analyze its safety. Methods: The incidence of post-phacoemulsification endophthalmitis before and after the introduction of antibiotic prophylaxis with cefuroxime was compared. Data were extracted from the electronic medical records of patients who underwent cataract surgery between July 2019 and July 2022 at a tertiary-care hospital. Data were also collected from the Hospital Infection Control Service database. Statistical analysis was performed to assess the efficacy of cefuroxime prophylaxis in reducing endophthalmitis rates. Results: Of the 4459 cataract surgeries included in the study, 2247 were included in the control group (pre-cefuroxime), and 2212 were included in the post-cefuroxime (ATB-P) Group. In the control group, 6 (0.13%) cases of endophthalmitis were reported. In the ATB-P Group, there were no cases of acute endophthalmitis. The frequency of endophthalmitis was significantly higher in the control group than in the ATB-P Group (p=0.016). Furthermore, Staphylococcus sp. was the most identified causative agent (75%). No adverse effects were reported after cefuroxime administration. Conclusion: The introduction of intracameral prophylaxis with cefuroxime significantly reduced the incidence of post-cataract surgery endophthalmitis. Additionally, its administration is safe. Purpose postcataract post safety Methods postphacoemulsification phacoemulsification compared 201 202 tertiarycare tertiary care hospital database Results 445 study 224 precefuroxime, precefuroxime pre , (pre-cefuroxime) 221 postcefuroxime ATBP ATB P (ATB-P 0.13% 013 0 13 (0.13% p=0.016. p0016 p p=0.016 . 016 (p=0.016) Furthermore sp 75%. 75 75% (75%) Conclusion Additionally safe 20 44 22 (pre-cefuroxime 0.13 01 1 (0.13 p001 p=0.01 (p=0.016 7 (75% 2 4 0.1 (0.1 p00 p=0.0 (p=0.01 (75 0. (0. p0 p=0. (p=0.0 (7 (0 p=0 (p=0. ( p= (p=0 (p= (p

ABSTRACT Purpose: Keratoconus presents certain peculiarities in pediatric patients when compared with adults. The greatest challenge in children is that the disease is more severe and faster in progression. In this retrospective study, we aimed to compare the accelerated and Dresden protocols for corneal crosslinking in patients aged <18 years who were followed-up for at least 12 months. Methods: A total of 36 eyes from 27 patients were included in the study. The best corrected and uncorrected visual acuity, maximal keratometry, corneal thickness, foveal thickness, and endothelial microscopy findings were evaluated at baseline and during the postoperative period at one, three, and six months. Thereafter, the patients were evaluated at one, three, six and twelve months postoperative. Corneal crosslinking was performed in all patients via the Dresden protocol (n=21 eyes) or the accelerated protocol (n=15 eyes). Data between the two groups were compared and XY statistical analysis was used. Results: Both protocols were effective in halting keratoconus progression. No patient had progression at the 12-month follow-up. A significant reduction in Kmax and improvement in the corrected distance visual acuity were observed only in the Dresden protocol group. Although the Dresden protocol was superior to the accelerated protocol in reducing Kmax (p=0.002), there was no significant difference in corrected distance visual acuity between the two groups. Conclusion: The accelerated protocol is as efficient as the Dresden protocol in stabilizing keratoconus progression. Although the Dresden protocol was superior to the accelerated protocol in reducing the Kmax, it did not produce better clinical results. Thus, the accelerated protocol is an efficient option. Furthermore, considering the advantages of reduced surgical time, the accelerated protocol is effective in halting keratoconus progression in the pediatric age group. Purpose adults study 18 <1 followedup followed up 1 Methods 3 2 keratometry thickness one three Thereafter n=21 n21 n 21 (n=2 n=15 n15 15 (n=1 eyes. . used Results 12month month followup. followup follow up. follow-up group p=0.002, p0002 p p=0.002 , 0 002 (p=0.002) Conclusion results Thus option Furthermore time < n=2 n2 (n= n=1 n1 p000 p=0.00 00 (p=0.002 n= (n p00 p=0.0 (p=0.00 p0 p=0. (p=0.0 p=0 (p=0. p= (p=0 (p= (p

RESUMO: Uma das causas de perda de produtividade em lavouras de cana está associada à espécie Diatraea saccharalis, também conhecida por broca da cana. Portanto, este estudo avaliou a viabilidade do uso de sensores hiperespectrais para obter a resposta espectral foliar da cana-de-açúcar em diferentes períodos de infestações, tanto a nível foliar quanto dossel, a fim de diagnosticar antecipadamente os danos da Diatraea saccharalis. O estudo contou com três variedades de cana-de-açúcar: CTC9003BT, CTC4 e RB966928. Em metade das parcelas foi utilizado o inseticida Altacor® para o controle de pragas. As coletas de dados ocorreram nas fases: brotação, perfilhamento, crescimento de colmos e início da maturação. Para avaliar os efeitos da broca na cana foi coletado os dados referentes ao conteúdo relativo de água (CRA), assinatura espectral foliar em laboratório e dossel, índices de vegetação (NDVI e MCARI), produtividade, pureza e ATR (Açúcar Total Recuperável). O maior CRA encontrado foi para a CTC9003BT (60,15%) sem inseticida e 59,0% com inseticida. As faixas espectrais do visível (400-680 nm) e infravermelho próximo (750-1300 nm) identificaram variações espectrais nas plantas com e sem broca. O percentual de broca apresentou correlações altas e negativas entre a produtividade, NDVI e ATR, com coeficientes de -0,68, -0,76 e -0,76, respectivamente. Os índices NDVI e MCARI foram eficazes na detecção de plantas sob estresse, contudo, sua variação é influenciada por múltiplos fatores, sendo difícil associá-los a um único problema (broca). RESUMO saccharalis Portanto canadeaçúcar açúcar infestações dossel CTCBT CTC BT RB966928 RB Altacor pragas fases brotação perfilhamento maturação CRA, , (CRA) MCARI, MCARI) Açúcar Recuperável. Recuperável . Recuperável) 60,15% 6015 60 15 (60,15% 590 59 0 59,0 400680 400 680 (400-68 nm 7501300 750 1300 (750-130 0,68, 068 68 -0,68 0,76 076 76 -0,7 0,76, respectivamente estresse contudo fatores associálos associá los (broca) RB96692 (CRA 60,15 601 6 1 (60,15 5 59, 40068 40 (400-6 750130 75 130 (750-13 0,68 06 -0,6 0,7 07 7 -0, (broca RB9669 60,1 (60,1 4006 4 (400- 75013 13 (750-1 0,6 0, -0 RB966 60, (60, (400 7501 (750- - RB96 (60 (40 (750 RB9 (6 (4 (75 ( (7

ABSTRACT: One of the causes of productivity loss in sugarcane cultivation has been associated with the species Diatraea saccharalis, also known as the sugarcane borer. Therefore, this study evaluated the feasibility of using hyperspectral sensors to obtain the leaf spectral response of sugarcane in different periods of infestation at leaf and canopy levels to diagnose D. saccharalis damage in advance. The study included three varieties of sugarcane: CTC9003BT, CTC4, and RB966928. The insecticide Altacor® was used to control pestsin half of the plots. Data collection occurred at the following stages: sprouting, tillering, stalke longation, and early maturation. Data regarding relative water content (RWC), leaf spectral signature in the laboratory and canopy, vegetation indices (NDVI and MCARI), productivity, purity, and total recoverable sugar (TRS) were collected to evaluate the borer effects on the sugarcane crop. The highest RWC was observed for CTC9003BT (60.15%) without insecticide and 59.0% with insecticide. The visible (400-680 nm) and near-infrared (750-1300 nm) spectral bands identified spectral variations in plants with and without sugarcane borer. The percentage of sugarcane borer showed high and negative correlations between productivity, NDVI, and TRS, with coefficients of -0.68, -0.76, and -0.76, respectively. The NDVI and MCARI indices effectively detect plants under stress, but their variation is influenced by multiple factors, making it difficult to associate them with a single problem (sugarcane borer). ABSTRACT Therefore D advance CTCBT CTC BT CTC4 RB966928 RB Altacor plots stages sprouting tillering longation maturation RWC, , (RWC) MCARI, MCARI) purity TRS (TRS crop 60.15% 6015 60 15 (60.15% 590 59 0 59.0 400680 400 680 (400-68 nm nearinfrared near infrared 7501300 750 1300 (750-130 0.68, 068 68 -0.68 0.76, 076 76 -0.76 respectively stress factors . borer) RB96692 (RWC 60.15 601 6 1 (60.15 5 59. 40068 40 (400-6 750130 75 130 (750-13 0.68 06 -0.6 0.76 07 7 -0.7 RB9669 60.1 (60.1 4006 4 (400- 75013 13 (750-1 0.6 -0. 0.7 RB966 60. (60. (400 7501 (750- 0. -0 RB96 (60 (40 (750 - RB9 (6 (4 (75 ( (7

RESUMO: A principal via de transmissão do coronavírus bovino (BCoV) é o contato direto com secreções e fezes, podendo ocorrer também por meio de superfícies contaminadas. Uma revisão sistemática, seguindo as recomendações PRISMA, foi realizada para avaliar a presença de BCoV em superfícies ambientais. A busca na literatura foi realizada em março e abril de 2023 e as bases de dados utilizadas foram Web of Science, PubMed, Scopus, Science Direct e Springer. A revisão sistemática seguiu a estrutura PEO: População - superfícies ambientais; Exposição - contato com BCoV; Resultado - identificação da presença ou infectividade de BCoV. As informações primárias foram registradas por meio de um formulário de extração, organizando métodos para detectar a presença de BCoV, avaliar a infectividade de BCoV, tipos de superfícies avaliadas e tipo de estudo. Os termos de pesquisa “coronavírus bovino” e “BCoV” resultaram em 2703 artigos. Após remover 964 duplicatas e excluir 1546 artigos que não mencionavam o BCoV nos títulos, 193 estudos foram submetidos à leitura de resumos. Seguindo os critérios de exclusão, que não abordavam a presença do BCoV no ambiente, três artigos foram selecionados para revisão abrangente. Nestes artigos foi identificada a presença de BCoV em vários tipos de superfícies, sendo possível a detecção até 81 horas após a contaminação, dependendo do tipo de superfície. Apesar do número limitado de estudos que investigam a presença de BCoV em superfícies, os resultados sugerem o potencial de transmissão de BCoV por meio de superfícies contaminadas, devido à capacidade do vírus permanecer infeccioso por até 24 horas em fômites. Esta revisão destaca a necessidade de mais pesquisas sobre a persistência de BCoV em locais de criação de bovinos, uma área atualmente carente de estudos específicos. RESUMO (BCoV fezes contaminadas PRISMA ambientais 202 PubMed Scopus Springer PEO extração estudo “BCoV 270 96 154 títulos 19 resumos exclusão ambiente abrangente 8 contaminação superfície 2 fômites bovinos específicos 20 27 9 15 1

ABSTRACT: The main transmission route of bovine coronavirus (BCoV) is direct contact with secretions and feces, and potentially also via contaminated surfaces. Following PRISMA guidelines, a systematic review was conducted to evaluate the presence of BCoV on environmental surfaces. A literature search, conducted between March and April 2023, utilized databases including Web of Science, PubMed, Scopus, Science Direct, and Springer. The review adhered to the PEO structure: Population - environmental surfaces; Exposure - contact with BCoV; Outcome - identification of presence or infectivity. Primary data were recorded using an extraction form organizing methods for detecting BCoV presence, assessing BCoV infectivity, types of surfaces evaluated, and study type. Search terms “Bovine coronavirus” and “BCoV” yielded 2703 articles. After removing 964 duplicates and excluding 1546 articles not mentioning BCoV in titles, 193 studies underwent abstract reading. Following exclusion criteria not addressing BCoV presence in the environment, three articles were selected for comprehensive review. These articles identified BCoV presence on various types of surfaces, with detection possible up to 81 hours after contamination, depending on surface type. Despite limited studies on BCoV presence on surfaces, findings suggested potential transmission via contaminated surfaces due to the virus’s ability to remain infectious for up to 24 hours on fomites. This review underscores the need for further research on BCoV persistence in farm environments, an area currently lacking focused studies. ABSTRACT (BCoV feces guidelines search 2023 PubMed Scopus Direct Springer structure infectivity evaluated type Bovine “BCoV 270 96 154 titles 19 reading environment 8 contamination viruss virus s 2 fomites environments 202 27 9 15 1 20