ABSTRACT Introduction: Chikungunya virus (CHIKV) is an alphavirus with a single-stranded RNA genome belonging to the Togaviridae family. It is transmitted through the bite of mosquitoes of the Aedes sp. genus and is characterized by fever and disabling joint pain. Objetive: Determine the clinical and epidemiological characteristics of the chikungunya virus in pediatric patients who attended a Regional Hospital in Paraguay between January and June 2023. Materials and method: Quantitative, observational, descriptive cross-sectional study. All patients with variables of interest were included in the study; sex, age, origin, clinical findings and atypical symptoms. Results: A total of 465 clinical records of patients with confirmed chikungunya were reviewed. The minimum age of the patients was four days, and the maximum was 17 years; half of the patients were between 1 and 10 years of age. Male predominance in 52.7%, patients from urban areas in 72.5%. 62.6% had a typical presentation of chikungunya infection, and 37.4% had an atypical presentation. Fever, polyarthralgia, myalgia, headache, vomiting, and nausea predominated in the usual manner. In the atypical form, alterations of the cardiovascular system, bleeding dyscrasias, and pneumonia, among others, predominate. 4.3% presented complications, including encephalitis-meningoencephalitis and myocarditis. There was a death rate of 10.8%. Conclusion: Male sex predominated, coming from urban areas with typical presentation of chikungunya, with predominant symptoms of fever, polyarthralgia, and myalgia. Atypical form alteration of the cardiovascular system, bleeding dyscrasias, pneumonia. 4.3% presented complications, 10.8% died.

RESUMEN Introducción: El virus chikungunya (CHIKV), es un alfavirus con genoma de ARN monocatenario, perteneciente a la familia Togaviridae, transmitido a través de la picadura de mosquitos del género Aedes sp., caracterizada por fiebre y dolores articulares incapacitantes. Objetivo: Determinar las características clínicas y epidemiológicas del virus chikungunya en pacientes pediátricos que acudieron a un Hospital Regional de Paraguay entre enero y junio del 2023. Material y Métodos: Estudio cuantitativo, observacional, descriptivo de corte transversal. Se incluyeron en el estudio todos los pacientes que presenten variables de interés; sexo, edad, procedencia, hallazgos clínicos y síntomas atípicos. Resultados: Se ha realizado la revisión de 465 fichas clínicas de pacientes con cuadro confirmado de chikungunya. La edad mínima de los pacientes fue de 4 días y la máxima de 17 años, la mitad de los pacientes estuvieron ubicados entre 1 y 10 años de edad. El 62,6% tuvo una presentación típica del cuadro de infección por chikungunya, el 37,4% tuvo una forma de presentación atípica. El 4,3% presentó complicaciones entre las que se citan encefalitis-meningoencefalitis y miocarditis. El 10,8% tuvo desenlace fatal, obitó. Conclusión: En cuanto a los datos demográficos, hubo predominio del sexo masculino y procedencia urbana. En cuanto a la presentación clínica, se reportaron formas típicas con fiebre, polialtralgias y mialgias. Las formas atípicas se presentaron con alteración del sistema cardiovascular, discrasia sanguínea y neumonías asociadas. Los casos que se consideraron complicados representan el 4,3% de la muestra y fue del 10,8% la mortalidad.

SUMMARY OBJECTIVE: Obstructive sleep apnea syndrome (OSAS) is an underdiagnosed condition that causes recurrent episodes of partial or total collapse of the upper airways during sleep. It is associated with perioperative pulmonary complications. The STOP-BANG is a screening tool for assessing patients at risk of OSAS. The aim of this study was to assess the prevalence of patients with OSAS during pre-anesthetic evaluation at a hospital and its correlation with predictors of ventilation and difficult airway. METHODS: This is an observational, cross-sectional study carried out from January 2022 to September 2023. The questionnaire comprised demographic data (age, weight, BMI, type of surgery, and anesthesia), the STOP-BANG, predictors of difficult orotracheal intubation (Mallampati, mouth opening, thyromental distance, cervical mobility, and upper lip bite test), and predictors of difficult ventilation through a facial mask (male sex, absence of teeth, presence of beard, obesity, and >55 years). RESULTS: The study had the participation of 221 patients, of whom 121 presented with a STOP-BANG ≥3, with a prevalence of 54.2%. All patients undergoing bariatric surgeries presented STOP-BANG ≥3. No significant statistical relationships were found between predictors of difficult orotracheal intubation and STOP-BANG ≥3. However, significant statistical relationships were found in relation to predictors of difficult ventilation through the facial mask. OBJECTIVE (OSAS complications STOPBANG STOP BANG preanesthetic pre anesthetic airway METHODS observational crosssectional cross sectional 202 2023 age, age (age weight BMI surgery anesthesia, anesthesia , anesthesia) STOPBANG, BANG, Mallampati, Mallampati (Mallampati opening distance mobility test, test test) male sex teeth beard obesity 55 >5 years. years . years) RESULTS 22 12 3 ≥3 542 54 2 54.2% However 20 5 > 1 ≥ 54.2 54.

Abstract Objective: The objective of this study was to analyze masticatory characteristics in children from 7 to 10 years, and to compare these characteristics among normal weight, overweight and obese children. Methods: This is a cross-sectional study, conducted in northeast Brazil, with a sample of 160 children, aged 7 to 10 years. The authors evaluated: nutritional and dental status; food intake; masticatory parameters and orofacial myofunctional characteristics. The children were divided according to nutritional status into normal weight (n = 101), overweight (n = 33) and obesity (n = 26) groups. Results: The results showed that Obese children had a larger bite size (g) (median = 6.0, Q1-Q3 = 4.0-9.0, p = 0.049) and performed fewer masticatory sequences (median = 3.0, Q1-Q3 = 2.0-3.2, p = 0.024) than children with normal weight (median = 5.0, Q1-Q3 = 4.0-7.0; median = 4.0, Q1-Q3 = 3.0-5.0). Furthermore, obese children finished feeding in a shorter time (s) (median = 62.5, Q1-Q3 = 50.5-70.0, p = 0.039) than normal weight children (median = 66.0, Q1-Q3 = 56.5-78.0) and overweight children (median = 66.0, Q1-Q3 = 58.0-81.5). Conclusions: The present results suggest that obese children present changes in mastication, evidenced by larger bite-size, performing fewer masticatory sequences and rapid mastication, which may contribute to increased food consumption and the development of excess weight. Objective 1 years Methods crosssectional cross sectional Brazil 16 evaluated intake n 101, 101 , 101) 33 26 groups Results g (g 60 6 0 6.0 Q1Q3 QQ Q1 Q3 Q Q1-Q 4.09.0, 4090 4.0 9.0, 4 9 4.0-9.0 0.049 0049 049 30 3 3.0 2.03.2, 2032 2.0 3.2, 2 2.0-3.2 0.024 0024 024 50 5 5.0 4.07.0 4070 7.0 4.0-7.0 40 3.05.0. 3050 . 3.0-5.0) Furthermore s (s 625 62 62.5 50.570.0, 505700 50.5 70.0, 70 50.5-70.0 0.039 0039 039 660 66 66.0 56.578.0 565780 56.5 78.0 56 78 56.5-78.0 58.081.5. 580815 58.0 81.5 58 81 58.0-81.5) Conclusions mastication bitesize, bitesize size, bite-size 6. Q1Q 09 4.09.0 409 4. 90 9.0 4.0-9. 0.04 004 04 3. 03 2.03.2 203 20 2. 32 3.2 2.0-3. 0.02 002 02 5. 07 4.07. 407 7. 4.0-7. 05 3.05.0 305 3.0-5.0 62. 570 50.570.0 50570 505 50. 700 70.0 50.5-70. 0.03 003 66. 578 56.578. 56578 565 56. 780 78. 56.5-78. 081 58.081.5 58081 580 58. 815 81. 8 58.0-81.5 4.09. 9. 4.0-9 0.0 00 2.03. 2.0-3 4.07 4.0-7 3.05. 3.0-5. 57 50.570. 5057 70. 50.5-70 56.578 5657 56.5-78 08 58.081. 5808 58.0-81. 4.09 4.0- 0. 2.03 2.0- 3.05 3.0-5 50.570 50.5-7 56.57 56.5-7 58.081 58.0-81 3.0- 50.57 50.5- 56.5- 58.08 58.0-8 58.0-

Aim The study aimed to evaluate the accuracy of the maximum bilateral molar bite force and the Root Mean Square (RMS) Electromyography (EMG) index of the masticatory muscles in the maximum bilateral molar bite (MMBMax) of women with myogenic Temporomandibular Disorder (TMD) and asymptomatic. Methods This is a cross-sectional study, composed of 86 women allocated to the TMD Group (n=43) and Control Group (n=43) diagnosis through the Diagnostic Criteria for Temporomandibular Disorders. The maximum bilateral molar bite force was evaluated using a bite dynamometer and the RMS EMG index of the masticatory muscles (anterior temporalis, masseter) during 5 seconds of the MMBMax task. Student t-test was used for data comparison between accuracy of the bite force and RMS EMG of masticatory muscles during the MMBMax. Results The maximum bilateral molar bite force showed high accuracy (AUC=0.99) for the diagnosis of women with myogenic TMD and asymptomatic women, and the RMS EMG index evaluated during the MMBMax showed a moderate level of accuracy for all masticatory muscles (AUC=0.70 to 0.75). Conclusion The bilateral bite dynamometer with a surface EMG during bilateral bite can be used to diagnose TMD in young women. (RMS (EMG (MMBMax (TMD crosssectional cross sectional 8 n=43 n43 n 43 (n=43 Disorders anterior temporalis masseter task ttest t test AUC=0.99 AUC099 AUC 0 99 (AUC=0.99 AUC=0.70 AUC070 70 (AUC=0.7 0.75. 075 0.75 . 75 0.75) n=4 n4 4 (n=4 AUC=0.9 AUC09 9 (AUC=0.9 AUC=0.7 AUC07 7 (AUC=0. 07 0.7 n= (n= AUC=0. AUC0 (AUC=0 0. (n AUC=0 (AUC= AUC= (AUC

Abstract The present cross-sectional study aimed to analyze the relationship between awake bruxism and fatigue of masticatory muscles in healthy young adults. For this purpose, 121 graduate students participated in this study. Frequency of awake bruxism was collected for 7 consecutive days by ecological momentary assessment (EMA) using an online survey (mentimeter). Muscle fatigue was tested one day after EMA assessment, which consisted of voluntarily and continuously clenching at 30% (kgf/cm2) of maximum bite force (MBF) until exhaustion. The percentage of change in MBF after the clenching task, as compared to the MBF before the clenching task was measured. The average frequency of awake bruxism was 45.5% during 7 days. Sustained clenching resulted in a significant reduction in MBF values in the total sample (p < 0.05). Nevertheless, no significant correlation was found between frequency of awake bruxism behaviors and percent of change in MBF and endurance time during the fatigue test. Therefore, it can be concluded that young healthy adults present a relatively high frequency of awake bruxism behaviors that do not seem to impact the degree of masticatory muscle fatigue. crosssectional cross sectional purpose 12 (EMA mentimeter. mentimeter . (mentimeter) 30 kgf/cm2 kgfcm2 kgfcm kgf cm2 cm (kgf/cm2 (MBF exhaustion measured 455 45 5 45.5 p 0.05. 005 0.05 0 05 0.05) Nevertheless test Therefore 1 (mentimeter 3 kgf/cm (kgf/cm 4 45. 00 0.0 0.

ABSTRACT Objective: This systematic review aims to answer the following focus question: “Is there an association between atypical swallowing and malocclusions?”. Methods: Appropriate word combinations were chosen and tailored specifically for each of the following electronic databases: EMBASE, Latin American and Caribbean Literature in Health Sciences (LILACS), LIVIVO, PubMed/Medline, Scopus, Web of Science, and gray literature, without any restrictions, up to February 2021. According to the selection criteria, only cross-sectional studies were included. The following inclusion criteria were considered: a sample composed of children, adolescents, and adults; patients clinically diagnosed with atypical swallowing; patients with normal swallowing; and outcome of interest of atypical swallowing in patients with malocclusion. The data consisted of study characteristics, sample characteristics, results, and conclusion of each study. The risk of bias was assessed using the JBI Critical Appraisal Checklist for Analytical Cross-Sectional Studies, and the certainty of evidence was assessed using the GRADE tool. Results: 4,750 articles were identified. After a two-step selection, four studies were included. A higher frequency of distal occlusion, extreme maxillary overhang, and open bite was related to swallowing disorders; most studies pointed to posterior crossbite as a malocclusion more associated with atypical swallowing. All studies had a moderate to high risk of bias, and the certainty of evidence was very low. Conclusion: The results indicate that atypical swallowing is associated with malocclusions and that posterior crossbite is the main malocclusion found, but only in the young population (3-11 years). Registration: PROSPERO (42020215203). Objective question Is malocclusions. . malocclusions?” Methods databases EMBASE LILACS, LILACS , (LILACS) LIVIVO PubMedMedline PubMed Medline PubMed/Medline Scopus Science literature restrictions 2021 crosssectional cross sectional included considered children adolescents adults characteristics CrossSectional Cross Sectional Studies tool Results 4750 4 750 4,75 identified twostep two step occlusion overhang disorders low Conclusion found 311 3 11 (3-1 years. years years) Registration 42020215203. 42020215203 (42020215203) malocclusions? (LILACS 202 475 75 4,7 31 1 (3- 4202021520 (42020215203 20 47 7 4, (3 420202152 (4202021520 2 ( 42020215 (420202152 4202021 (42020215 420202 (4202021 42020 (420202 4202 (42020 420 (4202 42 (420 (42 (4

RESUMO Objetivo: A presente revisão sistemática tem como objetivo responder à seguinte questão focal: “Existe associação entre deglutição atípica e más oclusões?”. Métodos: Combinações de palavras e truncamentos apropriados foram adaptados para as bases de dados eletrônicas: EMBASE, Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS), LIVIVO, PubMed/Medline, Scopus e Web of Science e a literatura cinzenta, sem qualquer restrição, até fevereiro de 2021. Os critérios de inclusão foram: estudos transversais; amostra composta por crianças, adolescentes e adultos; pacientes com diagnóstico clínico de deglutição atípica; pacientes com deglutição normal, e o desfecho de interesse foi deglutição atípica em pacientes com má oclusão. Os dados extraídos de cada estudo foram características do estudo, da amostra e a conclusão. O risco de viés foi avaliado usando a Lista de verificação de avaliação crítica da JBI para estudos transversais analíticos, e a certeza das evidências foi avaliada usando a ferramenta GRADE. Resultados: Foram identificados 4.750 artigos. Após uma seleção em duas fases, quatro estudos foram incluídos. Maior frequência de disto-oclusão, protuberância maxilar extrema e mordida aberta foram relacionadas a distúrbios da deglutição, com a maioria dos estudos apontando para mordida cruzada posterior como a má oclusão mais associada à deglutição atípica. Todos os estudos tiveram um risco de viés moderado a alto, e a certeza das evidências foi considerada muito baixa. Conclusão: Os resultados indicam que a deglutição atípica está associada à mordida cruzada posterior apenas na população jovem de 3 a 11 anos. Objetivo focal Existe oclusões. oclusões . oclusões?” Métodos eletrônicas EMBASE LatinoAmericana Latino Americana LILACS, LILACS , (LILACS) LIVIVO PubMedMedline PubMed Medline PubMed/Medline cinzenta restrição 2021 crianças adultos normal conclusão analíticos GRADE Resultados 4750 4 750 4.75 artigos fases incluídos distooclusão, distooclusão disto oclusão, disto-oclusão alto baixa Conclusão 1 anos oclusões? (LILACS 202 475 75 4.7 20 47 7 4. 2

ABSTRACT: The displacement of the articular disc (AD) constitutes an intracapsular arthropathy in which the disc is displaced from its functional relationship with the mandibular condyle and the articular portion of the temporal bone. It is frequently medial, anteromedial, or anterolateral, with posterior displacement being rare. The objective of this report was to describe the clinical manifestations and magnetic resonance imaging (MRI) of a disc posterior displacement (PDD) in the temporomandibular joint (TMJ). Case presentation: a 35-year-old male patient who reported on clinical examination, pain on lateral and posterior palpation in the left TMJ; mandibular deviation to the right side, difficulty in making lateral movements, and limitation of mouth opening were observed. Intraorally, cross bite was observed in the right canine area and wear facets in the upper canines and lower incisors. In closed mouth MRI sagittal views, the flattening of the DA, the location of the anterior band on the anterior aspect of the mandibular head, was verified in both joints, so that the rest of the disc was extended towards the posterior aspect, occupying part from the retrodiscal zone; in the coronal plane the position of the DA was closely related to the lateral and medial poles of condyle. Imaging characteristics were suggestive of PDD. Conclusions: PDD is a rare arthropathy of the TMJ, since MRI images accurately show the DA-condyle relationship, which enables its diagnosis and allows the clinician to make the best decisions for patient care.

RESUMEN: El desplazamiento del disco articular (DA) constituye una artropatía intracapsular en la que el disco se desplaza de su relación funcional con el cóndilo mandibular y la porción articular del hueso temporal. El desplazamiento del disco puede ser antero-medial, anterior, antero-lateral, lateral, medial o posterior, siendo este último uno de los menos frecuentes. El presente reporte tuvo como objetivo describir las manifestaciones clínicas y evaluación imagenológica mediante resonancia magnética (RM) de un desplazamiento posterior del disco (DPD) en la articulación temporomandibular (ATM). Presentación del caso: paciente masculino, de 35 años de edad quien a la exploración clínica, refirió dolor a la palpación lateral y posterior en la ATM izquierda, se observó desvío mandibular hacia el lado derecho, dificultad para realizar movimientos de lateralidad y limitación de la apertura oral. Intraoralmente, se evidenció mordida cruzada en zona canina derecha y facetas de desgaste en caninos superiores e incisivos inferiores. En imágenes sagitales de RM a boca cerrada se verificó en ambas articulaciones, el aplanamiento del DA, la localización de la banda anterior sobre la vertiente anterior de la cabeza de la mandíbula, de manera que el resto del disco estaba extendido hacia la vertiente posterior, ocupando parte de la zona retrodiscal; en el plano coronal la posición del DA estaba íntimamente relacionada con los polos lateral y medial de la cabeza de la mandíbula. Las características imagenológicas fueron sugestivas de DPD. El DPD es una artropatía poco frecuente de la ATM, siendo que las imágenes por RM muestran con precisión la relación DA-cóndilo, lo que posibilita su diagnóstico y permite al clínico tomar las decisiones idóneas para la atención del paciente.

ABSTRACT Malocclusion is one of the most common oral disorders. Recognizing its importance leads to the need for epidemiological studies whose results guide the development of programs for its prevention, interception and treatment. The objective of the present investigation was to determine the frequency of malocclusion in the sagittal and transverse direction in secondary school students from the city of Asunción. A descriptive cross-sectional study was carried out. The study population was made up of students from 12 to 18 years old enrolled in public and private schools in the city of Asunción during 2017. The data collected from the oral inspection was recorded in clinical records and analyzed with the Epi-Info program. TM. The number of participants was 1047 students who met the inclusion criteria. Fifty two percent of the participants were female and 48% male. The frequency of malocclusion in the sagittal direction was 98%, and in the transverse direction it was 27.6%.Among sagittal malocclusions, the most frequent was Class I (53%). The frequency of crossbite was 23%, of which 43% presented an anterior crossbite and 57% a posterior crossbite. Of those who presented posterior crossbite, 61% were unilateral and 39% bilateral. An important frequency of malocclusions is observed in the study population indicative of the need of establishing actions for its timely diagnosis and treatment.

RESUMEN La maloclusión es uno de los trastornos bucodentales más comunes. Reconocer su importancia lleva a la necesidad de realizar estudios epidemiológicos cuyos resultados orienten el desarrollo de programas para su prevención, intercepción y tratamiento. El objetivo de la presente investigación fue determinar la frecuencia de maloclusión en sentido sagital y transversal en estudiantes de nivel secundario de la ciudad de Asunción. Se realizó un estudio descriptivo de corte transversal. La población de estudio estuvo conformada por los alumnos de 12 a 18 años inscriptos en colegios públicos y privados de la ciudad de Asunción durante el 2017. Los datos recabados de la inspección bucodental fueron anotados en fichas clínicas yanalizadas con el programa Epi-Info TM. El número de participantes fue de 1047 estudiantes que cumplieron con los criterios de inclusión. El 52% de los participantes fueron de sexo femenino y el 48% del sexo masculino. La frecuencia de maloclusión en sentido sagital fue del 98%, y en sentido transversal del 27,6%.Entre las maloclusiones en sentido sagital la más frecuente fue la Clase I (53%). La frecuencia de mordida cruzada fue del 23%, de los cuales, el 43% presentó mordida cruzada anterior y el 57% mordida cruzada posterior. De los que presentaron mordida cruzada posterior, el 61% fue unilateral y el 39% bilateral. Se observa una importante frecuencia de maloclusiones en la población de estudio indicativa de la necesidad de establecer acciones para su diagnóstico y tratamiento oportunos.

ABSTRACT The objective was to determine the prevalence of non-nutritive suction habits and their relationship with malocclusions and dentomaxillary anomalies in preschool children of Coronel Oviedo - Paraguay, during 2015. An observational, descriptive cross-sectional study with analytical component was carried out, with two-stage stratified probabilistic sampling. The study population consisted of boys and girls of the Pre-Primary Education (nursery, kindergarten and pre-school). The variables of the study were the non-nutritive suction (digital suction and suction of the pacifier, age, sex, onychophagia and the use of the feeding bottle). The data were collected through a survey addressed to the parents, accompanied by an oral inspection. Three hundred forty-four schoolchildren were included, 48.84% (168) was 5 years old and 52.91% (182) was male. Of the total, 13.08% (45) performed digital suction, 9.59% (33) pacifier suction and 38.95% (134) other habits. By differentiating the presence of habits with demographic characteristics, it was seen how the presence of digital suction was related to the open bite (p=0.000), the crossbite (p = 0.049), and the orientation of the incisors (p=0.000). ), the shape of the arch (p = 0.000), the cross sectional occlusion (p=0.046) and the sagittal occlusion (p = 0.000). The prevalence of non-nutritive suction habits in these school children was high and related to malocclusion and the appearance of dentomaxillary anomalies, so the education of parents for the prevention of these conditions is fundamental.

RESUMEN El objetivo fue determinar la prevalencia de hábitos de succión no nutritiva y su relación con maloclusiones y anomalías dentomaxilares en preescolares de Coronel Oviedo - Paraguay, durante el año 2015. Se realizó un estudio observacional, descriptivo de corte transversal con componente analítico, con muestreo probabilístico estratificado bietápico. La población de estudio estuvo constituida por niños del sexo masculino y femenino de la Educación Inicial (maternal, jardín y pre-escolar). Las variables del estudio fueron la succión no nutritiva (succión digital y succión del chupete, edad, sexo, onicofagia y el uso del biberón. Los datos fueron recabados mediante una encuesta dirigida a los padres; acompañada de la inspección bucodental. Fueron incluidos 344 escolares, el 48,84% (168) tenía una edad de 5 años y el 52,91% (182) era del sexo masculino. El 13,08% (45) realizaba succión digital, el 9,59% (33) succión de chupete y el 38,95% (134) otros hábitos. Al diferenciar la presencia de hábitos con las características demográficas se pudo apreciar como la presencia de succión digital estaba relacionada con la mordida abierta (p=0.000), la mordida cruzada (p=0.049), con la orientación de los incisivos (p=0.000), la forma de la arcada (p=0.000), y la oclusión de vista transversal (p=0.046) y sagitalmente (p=0.000). La prevalencia de hábitos de succión no nutritiva en estos escolares fue alta y estaba relacionada con la maloclusión y la aparición de anomalías dentomaxilares, por lo que la educación de padres para la prevención de dichas condiciones es fundamental.

Ehrlichiosis is a disease transmitted by tick's bite that affect dogs and humans caused by the species Ehrlichia canis and E. chaffeensis, respectively. These bacteria are obligated intracellular gram negatives, with a cocoid to pleomorph aspect and can infect monocytes and trigger symptoms such as high fever, anorexia, thrombocytopenia, hemorrhages, anemia, and some serious problems such as splenomegaly, hepatomegaly and meningitis. There are several diagnostic tests for ehrlichiosis such as the hematological ones that evaluate the morphology of the monocytes in search of morulae; serological tests that includes the search of anti-Ehrlichia antibodies, although they might be limited due to cross reaction with other species. In other hand, the culture of Ehrlichia species is an effective method to obtain antigens and even develop indirect immunofluorescence assays (IFA). The polymerase chain reaction offers a definitive diagnosis associated to the use of genus-specific and species-specific primers, as well as its increased sensibility and specificity, compared to the others methods. Thus, in this review, we will discuss various methods applied to the diagnosis of this disease, as well as the advantages and disadvantages that these present.

Resumen La ehrlichiosis es una enfermedad transmitida por la picadura de garrapatas que afecta a perros y humanos, causada por las especies Ehrlichia canis y E. chaffeensis, respectivamente. Estas bacterias son gramnegativas, intracelulares obligadas, de aspecto cocoide a pleomorfo, que infectan los monocitos y desencadenan síntomas como fiebre elevada, anorexia, trombocitopenia, hemorragias, anemia y problemas graves como esplenomegalia, hepatomegalia y meningitis. Para diagnosticar esta enfermedad existen diversos métodos, entre los que se encuentran los hematológicos que evalúan la morfología de los monocitos en búsqueda de mórulas y la serología, que incluye la búsqueda de anticuerpos anti-Ehrlichia, pero que se encuentra limitado debido a la reactividad cruzada que presenta. Por otra parte, el cultivo de especies de Ehrlichia ha resultado ser un método efectivo para la obtención de antígenos y así desarrollar ensayos por inmunofluorescencia indirecta (IFI). El método por reacción de polimerasa en cadena ofrece un diagnóstico definitivo por tener una mayor sensibilidad y especificidad que los otros métodos, al haberse desarrollado cebadores género-específicos, así como especie-específicos. En esta revisión, se discutirán los diversos métodos aplicados al diagnóstico de esta enfermedad, así como las ventajas y desventajas que estos presentan.

Abstract Many children manifest lymphadenopathy at some point in their childhood, mainly due to infectious diseases. A correct clinical history, physical examination and complementary tests are required to allow differential diagnosis. We describe the cases of two children who presented a similar clinical presentation of regional lymphadenopathies without fever or rash. Both had as antecedent the tick bite on the scalp. The clinical presentation and the positive serology to Rickettsias led us to the diagnosis of lymphadenopathy transmitted by ticks, TIBOLA, DEBONEL or SENLAT. The serological diagnosis in our cases is limited by the existence of cross reactions with the different species of Rickettsias in particular with R. conorii (which is the one usually detected in our environment) and even with other bacteria. The evolution of both cases was favorable with treatment of azithromycin for five days. Despite the difficulty involved in the interpretation of serological results, the diagnosis of this rickettsiosis can be made in the light of clinical and epidemiological data. It should be considered the simultaneous use of other techniques to increase diagnostic sensitivity, such as PCR techniques in skin biopsy that will give us the etiological diagnosis of the infection.

Resumen Muchos niños manifiestan linfadenopatías en algún momento de su infancia, debidas sobre todo a enfermedades infecciosas. Es precisa una buena historia clínica, exploración física y pruebas complementarias que permitan su diagnóstico diferencial. Se describen los casos de dos niños que presentaban un cuadro clínico similar de linfadenopatías regionales, sin fiebre ni exantemas. Ambos tenían como antecedente la picadura de garrapata en el cuero cabelludo. El cuadro clínico y la serología positiva a rickettsias nos llevaron al diagnóstico de linfoadenopatía transmitida por garrapatas, TIBOLA, DEBONEL o SENLAT. El diagnóstico serológico en nuestros casos se encuentra limitado por la existencia de reacciones cruzadas con las distintas especies de rickettsias, en concreto con R. conorii (que es la habitualmente detectada en nuestro medio) e incluso con otras bacterias. La evolución de ambos casos fue favorable con tratamiento de azitromicina durante cinco días. Pese a la dificultad que supone la interpretación de los resultados serológicos, el diagnóstico de esta rickettsiosis se puede hacer a la luz de los datos clínicos y epidemiológicos. Debe plantearse la utilización simultánea de otras técnicas para aumentar la sensibilidad diagnóstica como pueden ser en la actualidad las técnicas de reacción en cadena de la polimerasa en biopsia cutánea que nos darán el diagnóstico etiológico de la infección.

Resumen Las causas de las discrepancias transversales del maxilar superior pueden ser genéticas o ambientales. Se presenta un paciente de 17 años y 7 meses de edad. En su análisis clínico y radiográfico se diagnosticó como: Clase I esquelética, hiperdivergente, clase II molar y canina bilateral, mordida cruzada posterior bilateral, apiñamiento severo superior e inferior, órgano dental 22 cruzado. El tratamiento consistió de la fase de expansión maxilar y alineación, apertura de espacio para el 22, nivelación, detallado y retención. La aparatología utilizada brackets prescripción Roth ,022 x ,028, expansor maxilar tipo Hyrax, bandas en los molares 6’s superiores, tubos bondeables en 6’s y 7`s superiores e inferiores, open coil de Niti. La retención a cargo de circunferencial superior e inferior y fijo de 13-23 y 33-43, tiempo de tratamiento activo 1 año y 11 meses.

Abstract Causes of transverse discrepancies of the maxilla can be genetic or environmental. We present a patient of 17 years 7 months of age. In his clinical and radiographic analysis he was diagnosed as: Skeletal Class I, hyperdivergent, malocclusion class II bilateral molar and canine, bilateral posterior cross bite, severe upper and lower crowding, crossed dental organ. The treatment consisted of maxillary expansion and alignment, opening of space for 22, leveling, detailing and retention. The appliances used were brackets prescription Roth .022 x .028, maxillary expander type Hyrax, molar bands in the upper molars 6s, tubes in 6’s and 7’s upper and lower, open coil of Niti. The retention in charge of upper and lower circumferential retainer and a bonded retainer from 13- 23 and 33-43, time of active treatment 1 year 11 months.

ABSTRACT The rapid maxillary disjunction is an orthopedic procedure in which an expansion screw acting upon the medial palatal suture, is activated every day and causes its aperture in a short period of time, accompanied by an excessive symptomatology in the patients. The aim of this paper is showing the benefits provided by the maxillary palatal disjunction when activated only once a day (1/4 turn). A Hyrax type screw was used in a 14 years-old male patient who had an Angle´s Class III malocclusion (Syndromic Class I) together with a transversal superior micrognathism larger than 4 mm and a posterior bilateral cross bite with a Monzon´s curve indicating maxillary endognathia. The results showed the expansion of the medial palatal suture in seven weeks and as a consequence the expansion of the dental arch, the alleviation of dental crowding, and the correction of the anterior and posterior bilateral cross bite and what is most important, the distress caused to the patient was minimal.

RESUMEN La disyunción maxilar rápida es un procedimiento ortopédico en el que se realizan una serie de activaciones diarias a un tornillo de expansión que actúa sobre la sutura palatina media y provoca la apertura de la misma en un breve período de tiempo, puede acompañarse de excesiva sintomatología en los pacientes. El objetivo de este trabajo es mostrar los beneficios aportados por la disyunción palatina del maxilar al aplicar solamente una activación diaria (1/4 de vuelta). Para ello se empleó un tornillo tipo Hyrax en un paciente masculino de 14 años de edad que presentaba una maloclusión dental de Clase III de Angle (Sindrómica Clase I), acompañada de un micrognatismo transversal superior mayor de 4 mm, una mordida cruzada posterior bilateral y presencia de curva de Monzón, que indica endognasia del maxilar. En un período de tiempo de siete semanas se logró la apertura de la sutura palatina media y por consiguiente, el incremento de la longitud del arco dentario, la eliminación del apiñamiento además de la corrección de la mordida cruzada anterior y posterior bilateral, con escasa sintomatología referida por el paciente.

Resumen En la actualidad, la ortodoncia desempeña un papel muy importante en la vida de los pacientes. Han salido muchos sistemas ortodónticos al mercado tratando de que el tratamiento de ortodoncia sea más rápido, cómodo y eficaz. Sin duda alguna, el sistema de autoligado viene a revolucionar la ortodoncia, debido a que es un sistema pensado en la comodidad del paciente, así como reducir el tiempo disminuyendo la fricción. El lapso de tratamiento es un factor clave, ya que se puede dar estabilidad postretención, aun cuando este haya sido corto. Se presenta una paciente de 21 años, con clase II esquelético, hiperdivergente, clase I molar bilateral, clase I canina bilateral, mordida abierta anterior, mordida cruzada del segundo premolar superior derecho, caninos fuera de arco, apiñamiento moderado superior y leve inferior, líneas medias dentales desviadas superior de 1 mm a la derecha, e inferior de 0,5 mm a la izquierda hipoplasia generalizada del esmalte. Terceros molares ausentes. Se le realizó el tratamiento de alineación, nivelación, suavizado interproximal, detallado y retención.

Abstract Today, orthodontics plays a very important role in the lives of patients. There is many orthodontic systems market trying to orthodontic treatment faster, convenient and effective. The self-ligating system will revolutionize orthodontics because it is a thought system patient comfort and reduce time reducing friction. The treatment time is a key factor, because it can provide stability post retention, even when there has been short. A 21 years old female patient is presented with a skeletal class II, hyperdivergent, molar and canine bilateral class I, anterior open bite, second right premolar in crossbite, canines outside arc, moderated upper crowding and light lower crowding. Deviated lower midline 0.5 mm to left, widespread enamel hipoplasia. Third molars absent. She underwent in alighment, leveling, stripping, detailing and retention treatment. Keywords: Class II, cross bite, moderated crowding. Trainer.

ABSTRACT Introduction: The biomechanics between dental occlusion and body posture has generated a growing interest in the subject; Because of the different interrelationships between them and because postural problems have been observed in more than 90% of patients with malocclusion. Objective: To identify in the updated scientific literature the relationship between dental occlusion modifications and body posture, and its application in orthodontics. Material and Methods: A bibliographic review was carried out during the months of April 2015 to January 2016. Several sources of information were consulted in printed and digital format, bibliographic databases in the BVS of Infomed and online in PubMed, Lilacs, Medline and the Google search engine. Was used the advanced search strategy and for the selection of articles, there were taken into account the current criteria, last 5 years, and the methodological quality or validity of the studies. Results: We found scientific literature that addresses the possible relationship between alterations in body posture and Angle malocclusions class I, II and III; cross bite and alterations related to mouth breathing, as well as their implications for orthodontic diagnosis and treatment. Conclusions: Most investigations suggest some kind of relationship between occlusion and body postural modifications, although more research is needed in this field. Its elucidation may have implications for orthodontic diagnosis and treatment.

RESUMEN Introducción: La biomecánica entre la oclusión dentaria y la postura corporal ha generado un interés creciente sobre el tema; por las diferentes interrelaciones que se dan entre ellas y porque se han observado problemas posturales en más de 90% de los pacientes con maloclusión. Objetivo: Identificar en la literatura científica actualizada la relación entre las modificaciones de la oclusión dentaria y la postura corporal, y su aplicación en ortodoncia. Material y Métodos: Se realizó revisión bibliográfica durante los meses de abril de 2015 a enero de 2016. Se consultaron varias fuentes de información en formato impreso y digital, bases de datos bibliográficos en la BVS de Infomed y por internet en PubMed, Lilacs, Medline y el buscador Google. Se empleó la estrategia de búsqueda avanzada y para la selección de los artículos, se tuvieron en cuenta criterios de actualidad, últimos 5 años, y la calidad metodológica o validez de los estudios. Resultados: Se encontró literatura científica que aborda la posible relación entre las alteraciones de la postura corporal y las maloclusiones clase I, II y III de Angle; la mordida cruzada y las alteraciones vinculadas a la respiración bucal, así como sus implicaciones en el diagnóstico y tratamiento ortodóncico. Conclusiones: La mayoría de las investigaciones sugieren algún tipo de relación entre las modificaciones de la oclusión y la postural corporal, aunque son necesarias más investigaciones en este campo. Su elucidación puede tener implicaciones en el diagnóstico y el tratamiento ortodóncico.