Résumé Par la méthode historique-comparative, cet article aborde les impacts, sur les États-Unis, l’Allemagne et le Brésil, des quatre crises économiques internationales survenues jusqu’en 2019, en se concentrant principalement sur leurs effets sur le régime politique et le post-2008. Les pays sélectionnés ont eu des expériences autoritaires distinctes, anciennes ou actuelles. Je conceptualise l’État de manière tridimensionnelle : régime politique, appareil décisionnel et structure de domination politique appuyée sur des coalitions. J’argumente que les conjonctures internationales critiques ont tendance à avoir un impact sur cette tridimensionalité, facilitant l’observation de ses variations et continuités. Je formule et corrobore trois hypothèses sur ces crises : elles ont tendance à augmenter ou diminuer les niveaux de démocratie ou d’autocratie des régimes ou à les changer ; la réponse autocratisante dépend d’une relation de forces pro-entreprises, subordonnant les travailleurs ; l’engagement démocratique des acteurs s’oppose à l’autocratisation. La contribution à la littérature réside dans la manière d’aborder les processus d’autocratisation et de démocratisation, ici étudiés à travers les impacts des crises économiques internationales sur les États. Les conjonctures critiques éclairent les composants clés de la mutabilité du Léviathan. On examine le régime politique par la politique économique des relations entre l’État, les marchés et les classes sociales, et non exclusivement par les variables politico-institutionnelles. On analyse les mécanismes d’intersection de la sphère et des acteurs politico-institutionnels avec les structures et acteurs économiques et sociaux, qui, impactant la tridimensionalité de l’État, entraînent des changements de régime ou dans le régime. historiquecomparative, historiquecomparative historique comparative, comparative historique-comparative ÉtatsUnis, ÉtatsUnis États Unis, Unis États-Unis lAllemagne l Allemagne Brésil jusquen jusqu 2019 post2008. post2008 post 2008. 2008 post-2008 distinctes actuelles lÉtat État coalitions Jargumente J argumente lobservation observation continuités dautocratie d autocratie dune une proentreprises, proentreprises pro entreprises, entreprises pro-entreprises lengagement engagement soppose s oppose lautocratisation. lautocratisation autocratisation. autocratisation l’autocratisation daborder aborder dautocratisation démocratisation Léviathan lÉtat, État, sociales politicoinstitutionnelles. politicoinstitutionnelles politico institutionnelles. institutionnelles politico-institutionnelles dintersection intersection politicoinstitutionnels institutionnels sociaux qui 201 post200 200 post-200 20 post20 post-20 2 post2 post-2 post-

Resumen Por medio del método histórico comparativo, se abordan los impactos en los Estados de Estados Unidos, Alemania y Brasil, de las cuatro crisis económicas internacionales que han ocurrido hasta 2019, enfocándose, principalmente, en sus efectos en el régimen político y en el periodo posterior a 2008. Los países seleccionados tuvieron distintas experiencias autoritarias, antiguas o actuales. Defino al Estado de una forma tridimensional: régimen político, aparato decisor y estructura de dominación política respaldada en coaliciones. Argumento que las respectivas coyunturas críticas internacionales tienden a impactar esta tridimensionalidad, facilitando la observación de sus variaciones y continuidades. Así, formulo y corroboro tres hipótesis sobre esas crisis: tienden a aumentar o disminuir los niveles de democracia o autocracia de los regímenes o a cambiarlos; la respuesta autocratizante depende de una relación de fuerzas proempresarial que subordina a los trabajadores; y el compromiso democrático de los actores opera contra la autocratización. La contribución a la literatura se relaciona con el modo de abordar los procesos de autocratización y democratización aquí investigados por los impactos de las crisis económicas internacionales en los Estados. Las coyunturas críticas vislumbran componentes clave de la mutabilidad del Leviatán. Se investiga el régimen político a partir de la economía política de las relaciones entre Estado, mercados y clases sociales, y no exclusivamente por las variables político-institucionales. Se analizan mecanismos de intersección de la esfera y de los actores político-institucionales con las estructuras y actores económicos y sociales, que, impactando en la tridimensionalidad del Estado, implican cambios de régimen o en el régimen. comparativo Unidos Brasil 2019 enfocándose principalmente 2008 autoritarias actuales tridimensional coaliciones continuidades Así cambiarlos trabajadores Leviatán sociales políticoinstitucionales. políticoinstitucionales institucionales. institucionales 201 200 20 2

Abstract This study uses a historical-comparative method to examine the impacts of the four international economic crises that occurred until 2019 on the United States, Germany, and Brazil, focusing primarily on their effects on the political regime and the post-2008 period. The selected countries had different authoritarian experiences, either in the distant past or more recently. The State is conceptualized along three dimensions: political regime, decision-making apparatus, and the structure of political domination supported by coalitions. The argument is that the respective international critical junctures tend to impact this three-dimensionality, making it easier to observe their variations and continuities. Three hypotheses are formulated and corroborated regarding these crises: they tend to increase or decrease the levels of democracy or autocracy in regimes or change them; autocratization depends on a pro-business power balance that subordinates workers; the democratic commitment of actors operates against autocratization. This study’s contribution to the literature lies in the approach to processes of autocratization and democratization, which are investigated here through the impacts of international economic crises on States. Critical junctures shed light on key components of the mutability of the Leviathan. It investigates the political regime through the political economy of the relationships between the State, markets, and social classes, not exclusively through political-institutional variables. Mechanisms of intersection between the political-institutional sphere and economic and social structures and actors are analyzed. These mechanisms impact the three-dimensionality of the State, leading to changes in the regime or within the regime. historicalcomparative historical comparative 201 States Germany Brazil post2008 post 2008 post-200 period experiences recently dimensions decisionmaking decision apparatus coalitions threedimensionality, threedimensionality dimensionality, dimensionality continuities them probusiness pro business workers studys s democratization Leviathan markets classes politicalinstitutional institutional variables analyzed 20 post200 200 post-20 2 post20 post-2 post2 post-

Resumo Aborda-se, pelo método histórico-comparativo, impactos, nos Estados dos EUA, Alemanha e Brasil, das quatro crises econômicas internacionais ocorridas até 2019, focando-se, principalmente, em seus efeitos no regime político e no pós-2008. Os países selecionados tiveram distintas experiências autoritárias, remotas ou atuais. Conceituo o Estado tridimensionalmente: regime político, aparato decisor e estrutura de dominação política escorada em coalizões. Argumento que as respectivas conjunturas críticas internacionais tendem a impactar nesta sua tridimensionalidade, facilitando a observação de suas variações e continuidades. Formulo e corroboro três hipóteses sobre essas crises: elas tendem a aumentar ou diminuir os níveis de democracia ou autocracia dos regimes ou a mudá-los; a resposta autocratizante depende de uma relação de forças pró-empresarial, que subordine os trabalhadores; o compromisso democrático dos atores opera contra a autocratização. A contribuição com a literatura está no modo de abordagem dos processos de autocratização e democratização, aqui investigados pelos impactos das crises econômicas internacionais nos Estados. As conjunturas críticas iluminam componentes-chave da mutabilidade do Leviatã. Investiga-se o regime político pela economia política das relações entre Estado, mercados e classes sociais, e não exclusivamente pelas variáveis político-institucionais. Analisam-se mecanismos de intersecção da esfera e dos atores político-institucionais com as estruturas e atores econômicos e sociais, que, impactando na tridimensionalidade do Estado, ensejam mudanças de regime ou no regime. Abordase, Abordase Aborda se, se Aborda-se históricocomparativo, históricocomparativo histórico comparativo, comparativo histórico-comparativo EUA Brasil 2019 focandose, focandose focando focando-se principalmente pós2008. pós2008 pós 2008. 2008 pós-2008 autoritárias atuais tridimensionalmente coalizões continuidades mudálos mudá los mudá-los próempresarial, próempresarial pró empresarial, empresarial pró-empresarial trabalhadores democratização componenteschave componentes chave Leviatã Investigase Investiga sociais políticoinstitucionais. políticoinstitucionais institucionais. institucionais Analisamse Analisam 201 pós200 200 pós-200 20 pós20 pós-20 2 pós2 pós-2 pós-

Diaporthe phaseolorum, an endophyte isolated from Combretum lanceolatum, has exhibited diverse biological activities including antimicrobial, leishmanicidal, antitumoral, and herbicidal properties. Regardless of these activities, there remains limited research on its chemical constituents. Therefore, this study aimed to investigate the metabolome of D. phaseolorum employing mass spectrometry data dereplication through molecular networking and MolNetEnhancer tools. Twenty two molecular families were annotated, including prenol lipids, benzenoids, organoheterocyclic compounds, and nucleosides. Among the 41 nodes annotated, 36 metabolites were confirmed via spectral references, including alismol, farnesol, linoleic acid, tyramine, N-acetyl-tyramine, 5-methoxy-1H-indole-3-carbaldehyde, 6-pentyl-2H-pyran-2-one, and adenosine. Further node annotation was achieved through MolNetEnhancer, resulting in the classification of an additional 68 nodes into various molecular families. Consequently, this study represents a significant contribution to the identification of the D. phaseolorum metabolome, highlighting its secondary metabolites and providing valuable chemical insights to elucidate its demonstrated biological activities. lanceolatum antimicrobial leishmanicidal antitumoral properties constituents Therefore D tools annotated lipids benzenoids compounds nucleosides 4 3 references alismol farnesol acid tyramine Nacetyltyramine, Nacetyltyramine N acetyl N-acetyl-tyramine 5methoxy1Hindole3carbaldehyde, 5methoxy1Hindole3carbaldehyde methoxyHindolecarbaldehyde 5 methoxy 1H indole carbaldehyde, carbaldehyde H 5-methoxy-1H-indole-3-carbaldehyde 6pentyl2Hpyran2one, 6pentyl2Hpyran2one pentylHpyranone 6 pentyl 2H pyran 2 one, one 6-pentyl-2H-pyran-2-one adenosine Consequently Hindole Hpyran

ABSTRACT: Acute abdomen cases are among the most prevalent and challenging illnesses in equine medicine. The diagnosis includes anamnesis and detailed clinical evaluation of the patient, allowing the gathering of several important information and, additionally, the use of complementary exams helps to define the diagnosis and prognosis of each case. This research applied the multiple correspondence analysis (MCA) in data referring to clinical examination information and outcome of horses with colic referred to a hospital in Rio Grande do Sul, Brazil. Fifty eight horses were included in the analysis and, it was possible to identify significant differences between the groups, survivors and non-survivors. Related to clinical signs, non-survivor cases are distinguished by severe pain, lack of motility, mucosal alteration, capillary refill time greater than 2sec, heart rate more than 48bpm and presence of nasogastric reflux. As complementary exams, hematocrits and blood lactate demonstrate significative difference among the groups. The cardiovascular parameters, including heart rate, mucosal color and capillary refill time, were the variables with the greatest contribution to discriminate animals that non-survive from those that were discharged. Thus, clinical evaluation should not be underestimated and complementary exams should be used in conjunction to seek a better prognosis. The MCA allowed to visualize the data and predict the outcome of the patients. ABSTRACT medicine patient additionally case (MCA Sul Brazil groups nonsurvivors. nonsurvivors non survivors. non-survivors signs nonsurvivor survivor pain motility alteration 2sec sec bpm reflux parameters nonsurvive survive discharged Thus patients

RESUMO: Os casos de abdome agudo estão entre as doenças mais prevalentes e desafiadoras na medicina equina. O diagnóstico inclui a realização de anamnese e avaliação clínica detalhada do paciente, permitindo a coleta de diversas informações importantes e, adicionalmente, a utilização de exames complementares ajuda a definir o diagnóstico e prognóstico de cada caso. O objetivo principal deste trabalho foi aplicar a análise de correspondência múltipla (ACM) em dados referentes ao exame clínico e desfecho de cavalos com cólica encaminhados para um hospital no Rio Grande do Sul, Brasil. Foram incluídos 58 cavalos na análise e foi possível identificar diferenças significativas entre os grupos, sobreviventes e não sobreviventes. Relacionado aos sinais clínicos, os casos de óbito distinguem-se por dor intensa, falta de motilidade, alteração da mucosa, tempo de preenchimento capilar maior que 2seg., frequência cardíaca maior que 48bpm e presença de refluxo nasogástrico. Como exames complementares, o hematócrito e o lactato sanguíneo demonstraram diferença significativa entre os grupos. Os parâmetros cardiovasculares, como batimento cardíaco, coloração de mucosas e tempo de preenchimento capilar, foram as variáveis com maior contribuição para diferenciar animais que não sobreviveram dos que receberam alta hospitalar. Assim, a avaliação clínica não deve ser subestimada e os exames complementares devem ser utilizados em conjunto para buscar um melhor prognóstico. A ACM permitiu visualizar os dados e prever o desfecho dos pacientes. RESUMO equina paciente adicionalmente caso (ACM Sul Brasil 5 grupos clínicos distinguemse distinguem se intensa motilidade mucosa 2seg seg 2seg. bpm nasogástrico cardiovasculares cardíaco hospitalar Assim pacientes

Two poly(acrylic acid-b-acrylamide) copolymers, and a poly(acrylic acid) homopolymer were synthesized via reversible addition-fragmentation chain transfer (RAFT) polymerization and tested for nickel removal from aqueous media. RAFT was used for better interchain composition homogeneity and to facilitate the synthesis of the block copolymers. Liquid-phase polymer-based retention (LPR) was used to compare the nickel binding capacity. Uptake tests were carried out at pH 3.0, 4.0, and 5.0. Nickel adsorption isotherms in the range of 1 to 7 mmol L−1 were achieved and the Langmuir adsorption model was applied. Maximum binding capacity (Qm) of Ni2+ at 298 K depended on the composition of the copolymers and pH. The polyacid block (PAA) was the major structural feature responsible for high values of nickel binding. All materials presented better uptake at higher pH, probably due to polyacid deprotonation and the increase in the electrostatic interactions. Up to approximately 100 mg of nickel per gram of homopolymer could be retained at pH = 5.0. Even though the presence of a poly(acrylamide) block decreases the binding capacity compared to PAA, that block has a specific contribution to nickel binding and can also provide better features to the material as better solubilization, and others. polyacrylic poly acrylic acidbacrylamide acid b acrylamide acid-b-acrylamide additionfragmentation addition fragmentation (RAFT media Liquidphase Liquid phase polymerbased polymer based LPR (LPR 30 3 0 3.0 40 4 4.0 50 5 5.0 L1 L L− applied Qm (Qm Ni2 Ni 29 PAA (PAA interactions 10 polyacrylamide poly(acrylamide solubilization others 3. 4. 5. 2

Bulk precipitation (BP) samples were collected at two coastal urban sites and two montane Atlantic Forest (400 and 1000 m altitude) areas in southeastern Brazil from August 2008 to August 2009. These samples were analyzed for the major inorganic ions (H+, Na+, K+, Ca2+, Mg2+, Cl- and SO42-) found in rainwater. The concentrations of inorganic nitrogen species (NH4+, NO3- and NO2-) were compiled from a previous study. The volume-weighted mean (VWM) concentrations of inorganic ions differed spatially, with higher values at the coastal urban and coastal periurban sites. On a molar basis, Cl- and Na+ together comprised 60% of the total inorganic constituents at the coastal urban site and 34-42% at the other three sites, as it is the closest to the ocean. Magnesium was also primarily associated with sea-salt aerosol. Non-sea-salt (nss) fractions of K+, Ca2+ and SO42- comprised 68-93% of their VWM concentrations, indicating the contribution of natural (mostly biogenic) and anthropogenic (SO2 oxidation for the latter) sources. Finally, we found that the acidity of BP at the four sampling sites is primarily controlled by the NH4+, nss-Ca2+, nss-SO42-, and NO3- ions, resulting in VWM pH values ranging from 5.60 (lower montane forest) to 5.98 (coastal periurban site). (BP 400 (40 100 altitude 200 2009 H+, H (H+ Na K K+ Ca2 Ca Mg2 Mg Mg2+ Cl SO42 SO rainwater NH4 NH (NH4+ NO3 NO NO2 NO2- study volumeweighted volume weighted (VWM spatially basis 60 3442% 3442 34 42% 42 34-42 ocean seasalt sea salt aerosol Nonseasalt Non nss (nss 6893% 6893 68 93% 93 68-93 mostly biogenic SO2 (SO latter sources Finally NH4+ nssCa2+, nssCa2 nssCa nss-Ca2+ nssSO42, nssSO42 nssSO , nss-SO42- 560 5 5.6 lower forest 598 98 5.9 site. . site) 40 (4 10 20 H+ (H SO4 (NH4 6 344 3 4 34-4 689 9 68-9 nssCa2+ nss-Ca2 nssSO4 nss-SO42 56 5. 59 ( 1 2 (NH 34- 68- nss-Ca nss-SO4 nss-SO

The inhibition of the fatty acid amide hydrolase (FAAH), an endocannabinoid system component, emerged as a potentially new therapeutic target for a range of clinical disorders such as acute and chronic pain. Some α-ketoheterocycle derivatives demonstrated interesting analgesic and anti-inflammatory activities in vitro. Ligand-Based Drug Design techniques such as knowledge graph convolutional networks (kGCN) and hologram quantitative structure-activity relationship (HQSAR) using α-ketoheterocycle derivatives from five different datasets were generated to discover the relation between the chemical structures and the inhibition activity. Meanwhile, structure-based drug design simulations as interaction fields (MIF), molecular docking, and ligand sites studies (LSI) from FAAH were performed using Autogrid software and FTmap/FTsite servers. The results of both studies were merged to propose predictive models. The resulting kGCN model demonstrated adequate accuracy area under the curve by receiver operating characteristic (AUC-ROC 0.7922). From contribution maps of the Ligand-Based Drug Design (LBDD) models and the generated probes using MIF and LSI, it was observed that the oxazole ring, the ketone group, and the apolar chain present in the structures of the inhibitors are important, besides the evidence of the Cys269 and Val270 residues importance for the potential interaction, confirmed by carried docking studies. These fragments and structural information can be used to carry out new FAAH potential inhibitors studies and report kGCN as an accurate classification technique. FAAH, , (FAAH) component pain αketoheterocycle α ketoheterocycle antiinflammatory anti inflammatory vitro LigandBased Ligand Based (kGCN structureactivity structure activity HQSAR (HQSAR Meanwhile structurebased based MIF, (MIF) LSI (LSI FTmapFTsite FTmap FTsite servers AUCROC AUC ROC 0.7922. 07922 0.7922 . 0 7922 0.7922) LBDD (LBDD ring group important Cys Cys26 Val Val27 technique (FAAH (MIF 0792 0.792 792 Cys2 Val2 079 0.79 79 07 0.7 7 0.

RESUMO: O melão de polpa alaranjada honeydew apresenta elevado potencial nutricional e econômico, sendo amplamente apreciado como fruta doce e refrescante. Portanto, avaliar amostras comerciais de produtos tão relevantes para o mercado de frutas frescas é de grande importância. O objetivo deste estudo foi investigar a capacidade antioxidante, os parâmetros de qualidade e a composição química de melões do mercado brasileiro. Os valores de pH e ºBrix determinados para as amostras de melão foram 6,5 ± 0,30 e 9,2 ± 0,80 g/100 g (peso fresco), respectivamente, o que está de acordo com os resultados esperados para melões de alta qualidade. A análise cromatográfica revelou a sacarose (49% do açúcar total) como principal açúcar, seguida pela frutose (30%) e glicose (21%). Os carotenóides, que estão diretamente ligados à cor laranja característica, apresentaram teor total de 270,59 µg/g (peso seco). Além disso, o maior valor de b* comparado ao valor de a* indica a maior contribuição da cor amarela. Quanto ao potencial antioxidante, além de apresentar capacidade antioxidante para ambos os métodos aplicados, DPPH e FRAP, níveis variando de 16,40 ± 0,21 µmol equivalente de ácido ascórbico/g a 56,98 ± 0,80 µmol equivalente de Trolox/g (peso seco) foram encontrados nos extratos de melão. Ademais, os resultados foram maiores em termos de FRAP do que em DPPH. Desta forma, os resultados destacam os melões avaliados como fontes valiosas de compostos bioativos, como carotenóides e fenólicos, que contribuem para suas propriedades antioxidantes. Além disso, análises de cor, pH e teor de sólidos solúveis totais também refletem os atributos de qualidade. RESUMO econômico refrescante Portanto importância brasileiro 65 6 5 6, 030 0 30 0,3 92 9 2 9, 080 80 0,8 g100 100 g/10 peso fresco, fresco , fresco) respectivamente 49% 49 (49 30% (30% 21%. 21 21% . (21%) característica 27059 270 59 270,5 µgg µg seco. seco disso b amarela aplicados 1640 16 40 16,4 021 0,2 ascórbicog ascórbico 5698 56 98 56,9 Troloxg Trolox Ademais forma bioativos fenólicos antioxidantes 03 3 0, 08 8 g10 10 g/1 4 (4 (30 (21% 2705 27 270, 164 1 16, 02 569 56, g1 g/ ( (3 (21 (2

ABSTRACT: Orange-fleshed non-netted honeydew melon has high nutritional and economic potential, being widely appreciated as a refreshing sweet fruit. Therefore, evaluating commercial samples of such relevant products for the fresh fruit market is of great importance. This study investigated the antioxidant capacity, quality parameters, and chemical composition of honeydew melons from the Brazilian market. The values of pH and °Brix determined for melon samples were 6.5 ± 0.30 and 9.2 ± 0.80 g/100 g (fresh weight), respectively, which agree with the results expected for high-quality melons. The chromatography analysis revealed sucrose (49% of total sugar) as the main sugar, followed by fructose (30%) and glucose (21%). Carotenoids, which are directly linked to the characteristic orange color, showed a total level of 270.59 µg/g (dry weight). Additionally, the higher b* value compared to a* value indicates the highest yellow contribution. Regarding the antioxidant assays, in addition to presenting antioxidant capacity for both methods applied, DPPH and FRAP, levels ranging from 16.40 ± 0.21 µmol ascorbic acid equivalent/g to 56.98 ± 0.80 µmol Trolox equivalent/g (dry weight) were reported in melon extracts. Moreover, the results were higher in terms of FRAP than DPPH. Therefore, the results underscore the evaluated honeydew melons as valuable sources of bioactive compounds, such as carotenoids and phenolics, which contribute to their antioxidant properties. Besides, analyses of color, pH, and total soluble solids content also reflect the quality attributes. ABSTRACT Orangefleshed Orange fleshed nonnetted non netted potential Therefore importance parameters Brix 65 6 5 6. 030 0 30 0.3 92 9 2 9. 080 80 0.8 g100 100 g/10 weight, weight , respectively highquality 49% 49 (49 sugar 30% (30% 21%. 21 21% . (21%) Carotenoids color 27059 270 59 270.5 µgg µg dry weight. Additionally b contribution assays applied 1640 16 40 16.4 021 0.2 equivalentg equivalent 5698 56 98 56.9 extracts Moreover compounds phenolics properties Besides attributes 03 3 0. 08 8 g10 10 g/1 4 (4 (30 (21% 2705 27 270. 164 1 16. 02 569 56. g1 g/ ( (3 (21 (2

ABSTRACT: The development of a selection strategy and to obtain a precocious white oat progenies, homogeneous for flowering and with additions to panicle grain mass, reconciled to environmental stimuli controlled by air temperature. The experiment was conducted in the municipality of Augusto Pestana, in the state of Rio Grande do Sul, Brazil. The experimental design was in augmented blocks with intermediate control, the regular treatments corresponded to 238 white oat progenies and the common treatment was represented by the commercial control (URS Taura) arranged in three replications. The selection for grains weight per panicle, percentage of flowered plants, days to physiological maturity and accumulation of degrees day are due to a high genetic contribution, which indicated promising selection for these characters already in initial breeding generations. The accumulation of degrees days for physiological maturity defines that 41.94% of the progenies are selected as precocious. The genotype ideotype distance index (MGIDI) selected 20% of the white oat progenies with greater flowering uniformity, less accumulation of degrees days and high potential for grain mass per panicle. ABSTRACT temperature Pestana Sul Brazil 23 URS Taura replications plants contribution generations 4194 41 94 41.94 MGIDI (MGIDI 20 uniformity 2 419 4 9 41.9 41.

RESUMO: O objetivo deste trabalho foi desenvolver uma estratégia de seleção e obter progênies de aveia branca precoces, homogêneas para o florescimento e com acréscimos a massa de grãos da panícula, conciliados aos estímulos ambientais controlados pela temperatura do ar. O experimento foi conduzido no município de Augusto Pestana, no estado do Rio Grande do Sul, Brasil. O delineamento experimental de blocos aumentados com testemunha intercalar, os tratamentos regulares correspondem a 238 progênies de aveia branca e o tratamento comum foi representado pela testemunha comercial (URS Taura) disposta em três repetições. A seleção para peso de grãos por panícula, porcentagem de plantas floridas, dias para maturidade fisiológica e acúmulo de graus-dia devem-se a uma alta contribuição genética, o que indica uma seleção promissora para esses caracteres já nas gerações iniciais de melhoramento. O acúmulo de graus dias para a maturidade fisiológica define que 41,94% das progênies são selecionadas como precoces. O índice de distância genótipo ideótipo (MGIDI) selecionou 20% das progênies da aveia branca com maior uniformidade do florescimento, menor acúmulo de graus dias e alto potencial de massa de grãos por panícula. RESUMO precoces panícula ar Pestana Sul Brasil intercalar 23 URS Taura repetições floridas grausdia dia devemse devem se genética melhoramento 4194 41 94 41,94 MGIDI (MGIDI 20 2 419 4 9 41,9 41,

Abstract Standardized Work (SW) is an approach originated in the manufacturing industry, which aims to standardize and improve the efficiency of operations cycles, based on the Lean Production Philosophy. SW has the potential to support the implementation of Location-Based Planning and Control (LBPC) as it allows balancing the workload between workers or teams, contributing to the synchronization of processes. The aim of this study is to propose a method for implementing SW as an additional element of LBPC. Design Science Research was the methodological approach adopted in this investigation and an empirical study was carried out in a real estate company, in which the method for implementing SW was conceived and implemented.The following benefits were identified in the study: increase in the degree of process standardization, improvement in process synchronization, increase in the engagement of the work force with process standards, and improvement in terms of time reliability. The main contribution of this research study has been the adaptation of SW in the construction context as an additional element of LBPC. (SW industry cycles Philosophy LocationBased Location Based LBPC (LBPC teams processes company implementedThe implemented standardization standards reliability

Resumo Trabalho Padronizado (TP) é uma abordagem originária da indústria da manufatura que visa a padronizar e melhorar a eficiência dos ciclos de operações com base na Filosofia da Produção Enxuta. O TP tem o potencial de apoiar a implementação do Planejamento e Controle Baseado em Localização (LBPC), pois permite equilibrar a carga de trabalho entre os trabalhadores ou equipes, contribuindo para a sincronização de processos. O objetivo deste estudo foi desenvolver um método para implementação do TP como um elemento adicional do LBPC. Design Science Research foi a abordagem metodológica utilizada, sendo conduzido um estudo empírico em uma empresa atuante no mercado imobiliário, na qual o método para implementação do TP foi concebido e implementado. Os seguintes benefícios foram identificados no estudo: aumento do grau de padronização das operações, melhoria na sincronização entre processos, aumento do engajamento da mão-de-obra com padrões de processo, e melhoria em termos de confiabilidade em relação a prazos. A principal contribuição desta pesquisa para o avanço do conhecimento foi a adaptação da abordagem do TP ao contexto da construção civil como um elemento adicional do LBPC. (TP Enxuta LBPC, LBPC , (LBPC) equipes processos utilizada imobiliário implementado mãodeobra mão obra processo prazos (LBPC

Abstract Construction projects are highly complex systems that recurrently present discrepancies between work-as-imagined and work-as-done. Digital technologies, such as photogrammetry using UAVs (drones), are promising support tools to cope with this problem. Therefore, this study aims to evaluate the procedures for developing and assessing the quality of a 3D model generated through photogrammetry from images captured by a drone, comparing it to the as-designed BIM model. Thus, a case study was carried out in a residential low-income housing construction project in Camaçari, Brazil. Compared to the as-designed BIM 3D model, the photogrammetric model presented an average dimensional deviation of -1.68%. The model also presented issues such as occlusions and deformations. The study highlights that both this deviation and the quality of the photogrammetric model can be significantly influenced by the data collection method (e.g., quantity and resolution of photos). The study's primary contribution lies in presenting the potential of UAV usage for image capture in photogrammetry model generation. workasimagined work imagined workasdone. workasdone done. done work-as-done technologies drones, drones , (drones) problem Therefore D drone asdesigned designed Thus lowincome low income Camaçari Brazil 1.68%. 168 1 68 -1.68% deformations e.g., eg e g (e.g. photos. photos . photos) studys s generation (drones 1.68% 16 6 -1.68 e.g. (e.g 1.68 -1.6 e.g 1.6 -1. 1. -1 -

Resumo Projetos de construção são sistemas altamente complexos que apresentam recorrentemente discrepâncias entre o trabalho planejado e o trabalho realizado. Tecnologias digitais, como a fotogrametria com VANTs (drones), são ferramentas de suporte promissoras nesse contexto. Assim, este estudo tem como objetivo avaliar os procedimentos de desenvolvimento e qualidade de um modelo 3D gerado por fotogrametria através de imagens capturadas por drone, comparando-o ao modelo as-designed BIM. Para isso, realizou-se um estudo de caso em uma habitação de interesse social localizada em Camaçari-BA. Comparado ao modelo BIM projetado, o modelo fotogramétrico apresentou um desvio dimensional médio de -1,68%. O modelo também apresentou inconsistências como oclusões e deformações. O estudo mostra que tanto esse desvio como a qualidade do modelo fotogramétrico obtido podem ser consideravelmente influenciados pela forma de coleta dos dados (ex. baixa quantidade e resolução das fotos). A principal contribuição do estudo é apresentar o potencial do uso do VANT para captura de imagens para geração de um modelo de fotogrametria. realizado digitais drones, drones , (drones) contexto Assim D drone comparandoo comparando asdesigned as designed isso realizouse realizou se CamaçariBA. CamaçariBA Camaçari BA. BA Camaçari-BA projetado 1,68%. 168 1 68 -1,68% deformações ex. ex (ex fotos. fotos . fotos) (drones 1,68% 16 6 -1,68 1,68 -1,6 1,6 -1, 1, -1 -

Resumen Objetivo: cuantificar la incertidumbre asociada con la estimación del valor actual del ciclo económico. Metodología: se emplea el filtro de Baxter y King en una serie de tiempo ampliada con proyecciones, asumiendo caminata aleatoria, y se construyen intervalos de confianza para el ciclo de manera analítica y con bootstrap. Limitaciones: la calidad de los intervalos de confianza se deteriora en presencia de cambio estructural en la serie de tiempo. Originalidad: la originalidad subyace en proponer una metodología para determinar la fase actual del ciclo económico de manera conjunta con una cuantificación de la incertidumbre respecto a tal medición. Conclusión: para Costa Rica, el método propuesto conduce a estimaciones del ciclo económico menos sensibles a nuevos datos que lo obtenido con el filtro de Hodrick y Prescott, y simulaciones muestran que los intervalos de confianza propuestos proveen la confianza nominal especificada.

Abstract Objetive: To quantify the uncertainty associated to the estimation of the current value of the business cycle. Methodology: The Baxter and King filter is applied to an time series expanded with forecasts, assuming a random walk, and confidence intervals are build for the cyclical component both analytically and using bootstrap. Limitations: The quality of the confidence 1 intervals deteriorates when there is a structural break in the time series. Originality: The original contribution of this article is a proposed methodology to jointly determined the current phase of the business cycle and the uncertainty associated with such measurement. Conclusions: For Costa Rica, the proposed method provides estimations of the business cycle that are less sensitive to new data points than the Hodrick and Prescott filter, and simulations show that the proposed confidence intervals provide the specified nominal confidence.

Abstract What and how did the writers of the first centuries of the Italian language read? Thanks to the influence of what readings did you compose your works? In the case of Boccaccio and Petrarch, the answer to this question was found in the books they owned and in which in many cases they made notes. Of Dante, on the other hand, we do not possess either the books or a single word written in his handwriting: we can only imagine the appearance of his handwriting thanks to the description that Leonardi Bruni left of it, probably based on a Dantesque autograph, now lost. Given this lack of data, Dante’s sole mention of his own training is of great importance, that is, the passage from the Convivio in which he narrates that he undertook philosophical studies immediately after the death of Beatrix, prompted by the reading of the Consolatio Philosophiae of Boethius to go for thirty months “to the schools of the religious and to the disputes of the philosophers” (Conv. II, XII, 1-7). The schools frequented by the Poet can be identified with the conventual Studia of Florence, that is, the Franciscan of Santa Croce, the Dominican of Santa Maria Novella and the Augustinian of Santo Spirito, unique places of conservation of books and education, in addition to the teaching by isolated private teachers like Brunetto Latini. Among these institutions, home to lively cultural activity, philosophical disputes and study, the historical data attributable to Dante favors Santa Croce, whose books (today preserved mainly in the Biblioteca Medicea Laurenciana and in the National Central Library of Florence) document the physiognomy in which the texts he read were offered to his eyes and were models of his works. This contribution traces a journey through the precious bibliographic heritage of the Franciscan Studium, with the aim of reconstructing and documenting the circulation of Dante’s works in his homeland and the Florentine context in which the poet’s extraordinary cultural formation took place.

Resumen ¿Qué y cómo leían los escritores de los primeros siglos de la lengua italiana? ¿Bajo la influencia de qué lecturas compusieron sus obras? En el caso de Boccaccio y Petrarca, la respuesta a esta pregunta se encontró en los libros que poseían y en los que, en muchos casos, hicieron anotaciones. De Dante, en cambio, no poseemos ni los libros ni una sola palabra escrita de su puño y letra: sólo podemos imaginar el aspecto de su caligrafía gracias a la descripción que de ella dejó Leonardi Bruni, probablemente basada en un autógrafo dantesco, hoy perdido. Dada esta ausencia de datos, cobra gran importancia la única mención de Dante a su propia formación, es decir, el pasaje del Convivio en el que narra que emprendió estudios filosóficos inmediatamente después de la muerte de Beatriz, impulsado por la lectura de la Consolatio Philosophiae de Boecio para ir durante treinta meses “a las escuelas de los religiosos y a las disputas de los filósofos” (Conv. II, XII, 1-7). Las escuelas frecuentadas por el Poeta se pueden identificar con los Studia conventuales de Florencia, es decir, la franciscana de Santa Croce, la dominicana de Santa Maria Novella y la agustina de Santo Spirito, únicos lugares de conservación de libros y educación, además de la enseñanza privada de profesores aislados como Brunetto Latini. Entre estas instituciones, sedes de una animada actividad cultural, de disputas filosóficas y de estudio, los datos históricos atribuibles a Dante favorecen a Santa Croce, cuyos libros (hoy conservados principalmente en la Biblioteca Medicea Laurenciana y en la Biblioteca Nacional Central de Florencia) documentan los textos que leía y eran modelos de sus obras. Esta contribución traza un recorrido por el preciado patrimonio bibliográfico del Studium franciscano, con el objetivo de reconstruir y documentar la circulación de las obras de Dante en su patria y el contexto florentino en el que tuvo lugar la extraordinaria formación cultural del poeta.

Resumen La investigación tuvo como objetivo comprender las experiencias alrededor de la sexualidad desde la teoría de los holones en un grupo de mujeres diagnosticadas con cáncer ginecológico en la ciudad de Pereira, Colombia. Se implementó un diseño cualitativo y fenomenológico, con la participación de seis mujeres entre 30 y 60 años, a quienes se aplicaron entrevistas semiestructuradas explorando los holones de reproductividad, género, erotismo y vinculación afectiva interpersonal. Las entrevistas fueron transcritas y analizadas de forma manual, mediante codificación abierta y axial para identificar categorías emergentes. En los discursos de las mujeres se evidenciaron elementos relacionados a los holones de la sexualidad. En el holón de reproductividad, se encontró una resignificación del rol reproductivo como madres; en el holón de género, se presentaron actitudes positivas hacia el cuerpo y amenazas a la identidad de género por causa de los cambios provocados por la enfermedad; en el holón de erotismo, las mujeres relataron experiencias sexuales marcadas por el dolor y el apoyo erótico de la pareja; y en el holón de vinculación afectiva interpersonal, se evidenciaron situaciones de estabilidad conyugal, separación temporal con la pareja y sostenimiento de vínculos abusivos durante el proceso de tratamiento oncológico. Estos hallazgos muestran una amplia reconfiguración integral de la sexualidad femenina en cada uno de los holones y realizan un aporte significativo a la comprensión de las subjetividades de las mujeres en el proceso de afrontar el cáncer ginecológico. Se recomienda realizar nuevas investigaciones con mayor cantidad de participantes y en otras regiones de Colombia.

Abstract The research aimed to understand the experiences around sexuality, from the holon theory, in a group of women diagnosed with gynecological cancer from Pereira, Colombia. A qualitative and phenomenological design was carried out, with the participation of six women between 30 and 60 years of age, to whom semi-structured interviews were applied, exploring the holons of reproductivity, gender, eroticism and interpersonal affective bonding. The interviews were transcribed and analyzed manually, using open and axial coding to identify emerging categories. In the women's discourses, elements related to the holons of sexuality were evident. In the holon of reproductivity, a resignification of the reproductive role as mothers was found; in the holon of gender, positive attitudes towards their bodies and threats to gender identity due to the changes caused by the disease were presented; in the holon of eroticism, women reported sexual experiences characterized by pain and erotic support from their partners; and in the holon of affective interpersonal bonding, they reported situations of marital stability, temporary separation from their partners and abusive ties during the process of cancer treatment. These findings show a comprehensive reconfiguration of female sexuality in each of the holons and make a significant contribution to the understanding of women's subjectivities in the process of coping with gynecological cancer. Further research with a larger number of participants and in other regions of Colombia is recommended.

Abstract Introduction: The study describes the way in which a group of people justified drug trafficking activities on the northern border of México, based on the theory of neutralization. Objective: the objective of the study is to describe the way in which a group of people justified their activities related to drug trafficking on the northern border of Mexico. Methodology: Using qualitative methodology, through semi-structured interviews with 9 men and 2 women deprived of liberty for drug trafficking in Sonora, México, the various neutralization techniques that they considered in their process of entering these activities were explored. Conclusions: The results show that denial of responsibility and discrediting justice bodies are the most commonly used justifications. It is concluded that neutralization is a contribution to the understanding of social control, crime incidence and recidivism.

Resumo Introdução: O estudo descreve a forma como um grupo de pessoas justificou as atividades do tráfico de drogas na fronteira norte do México, com base na teoria da neutralização. Objetivo: o objetivo do estudo é descrever a forma como um grupo de pessoas justificou suas atividades relacionadas ao tráfico de drogas na fronteira norte do México. Metodologia: Utilizando metodologia qualitativa, por meio de entrevistas semiestruturadas com 9 homens e 2 mulheres privados de liberdade por tráfico de drogas em Sonora, México, foram exploradas as diversas técnicas de neutralização que eles consideraram em seu processo de ingresso nessas atividades. Conclusões: Os resultados mostram que a negação de responsabilidade e o descrédito dos órgãos de justiça são as justificações mais utilizadas. Conclui-se que a neutralização é uma contribuição para a compreensão do controle social, da incidência da criminalidade e da reincidência.

Resumen Introducción: el estudio describe la manera en que un grupo de personas justificaron actividades de tráfico de drogas en la frontera norte de México, partiendo de la teoría de la neutralización. Objetivo: el objetivo del estudio es describir la manera en que un grupo de personas justificaron sus actividades relacionadas con el tráfico de drogas en la frontera norte de México. Metodología: usando metodología cualitativa, mediante entrevista semiestructurada a 9 hombres y 2 mujeres privados de la libertad por tráfico de drogas en Sonora, México, se exploraron las diversas técnicas de neutralización que consideraron en su proceso de ingreso a dichas actividades. Conclusiones: los resultados muestran que la negación de la responsabilidad y desacreditar los órganos de justicia, son justificaciones de mayor uso. Se concluye que la neutralización aporta al entendimiento del control social, la incidencia y reincidencia delictiva.

Abstract Purpose: To analyze the contribution of the program "Sembrando Vida" in alleviating the poverty of male and female farmers using an Actor-Oriented Approach (AOA), to comprehend the program's impact on poverty reduction in Acayucan, Veracruz, Mexico. This analysis takes into consideration aspects such as employment, food self-sufficiency, the reconstruction of social fabric, forest recovery, the potential of territories, and overall well-being. Methodological design: This is an ethnographic study, using in-depth interviews and participant observation of ten farmers in the program over a period of seven months. The analysis of the information was carried out using NVivo software. Results: The program is partially fulfilling the objective to decrease poverty, because farmers still confront productive limitations, social vulnerability, higher investments, and technical-productive difficulties. Research limitations: The scope of the research only corresponds to the actors who participated in the research; therefore, the results cannot be generalized. Comparisons with more communities and with farmers not participating in the program would give a broader picture. Findings: This study contributes to the understanding of the impact of public interventions on development processes. The findings contribute to improving the implementation of the program and to developing future projects that consolidate the medium and long-term goals of the program.

Resumen Objetivo: analizar la contribución del programa Sembrando Vida en el alivio de la pobreza de campesinas y campesinos desde un Enfoque Orientado al Actor (EOA), para comprender el impacto del programa en la disminución de la pobreza en Acayucan, Veracruz, México; considerando aspectos como: el empleo, la autosuficiencia alimentaria, la reconstrucción del tejido social, la recuperación forestal, el potencial de territorios y el bienestar. Diseño metodológico: esta investigación cualitativa es de carácter etnográfico, realizando entrevistas a profundidad y observación participante a diez agricultores del programa durante un periodo de siete meses. El análisis de la información se realizó a través del software NVivo. Resultados: el programa está cumpliendo parcialmente con su objetivo de combate a la pobreza, puesto que los campesinos aún enfrentan limitaciones productivas, vulnerabilidad social, mayores inversiones y dificultad técnico-productiva. Limitaciones de la investigación: los alcances de la investigación solo corresponden a los actores que participaron en ella, por lo tanto, los resultados no pueden generalizarse. Comparar con más comunidades y con campesinos no participantes del programa daría una visión más amplia. Hallazgos: se aporta una mayor comprensión del impacto de las intervenciones públicas en los procesos de desarrollo. Lo encontrado suma para la mejora del programa en su aplicación y en el desarrollo de futuros proyectos que consoliden las metas a mediano y largo plazo del programa.