RESUMO Objetivo: Reconhecer e abordar a síndrome de Patau, apesar de sua raridade e da baixa expectativa de vida associada, por meio da apresentação de um estudo de caso de uma paciente de dois anos que recebe cuidados em casa por intermédio de serviços de home care. Descrição do caso: Apresentamos uma paciente do sexo feminino que desafiou as probabilidades, com sobrevivência prolongada devida, possivelmente, ao home care. Ela nasceu por cesariana, com 31 semanas + 4 dias, em razão da restrição do crescimento uterino. A mãe, de 36 anos, recebeu cuidados pré-natais adequados e gozava de boa saúde. O diagnóstico da síndrome de Patau foi confirmado por meio de cariótipo após o nascimento. Apesar da gravidade clínica do caso, a paciente, hoje com dois anos, recebe atendimento domiciliar especializado, apoiado por traqueostomia e gastrostomia. Um técnico de enfermagem dedicado 24 horas garante acompanhamento contínuo, e a paciente beneficia-se de check-ups médicos regulares, fisioterapia cinco vezes por semana, sessões semanais de fonoaudiologia, consultas mensais com nutricionista e apoio psicológico contínuo aos familiares. Comentários: Esta abordagem multidisciplinar resultou em melhora motora discreta, destacando o impacto positivo do cuidado integral no seu bem-estar geral. A existência de uma rede robusta de apoio às famílias que enfrentam desafios semelhantes é crucial, e um cuidado multidisciplinar pode prevenir eficazmente as complicações associadas a esta impactante síndrome. Objetivo associada care probabilidades devida possivelmente cesariana 3 dias uterino mãe prénatais pré natais saúde nascimento especializado gastrostomia 2 beneficiase beneficia se checkups check ups regulares semana fonoaudiologia familiares Comentários discreta bemestar bem estar geral crucial

ABSTRACT Objective: To recognize and address Patau’s syndrome, despite its rarity and associated low life expectancy, through the presentation of a case study of a 2-year-old patient receiving Home Care services. Case description: We present a female patient who defied the odds with a prolonged survival, possible due to Home Care. She was delivered via cesarean section at 31 weeks + 4 days due to restricted uterine growth. The mother, aged 36, had received proper prenatal care and was in good health. The diagnosis of Patau’s syndrome was confirmed through karyotyping after birth. Despite the severe clinical nature of the case, the patient, now with two years old, receives specialized home-based care, supported by a tracheostomy and gastrostomy. A dedicated 24-hour nursing technician ensures continuous monitoring, and the patient benefits from regular medical check-ups, physiotherapy five times a week, weekly speech therapy sessions, monthly consultations with a nutritionist, and ongoing psychological support for her family members. Comments: This multidisciplinary approach has resulted in a slight motor response, highlighting the positive impact of comprehensive care on her overall well-being. The existence of a robust support network for families facing similar challenges is crucial, and a multidisciplinary care can effectively prevent complications associated with this impactful syndrome. Objective Pataus Patau s expectancy 2yearold yearold 2 year old services description survival 3 growth mother 36 health birth homebased home based gastrostomy 24hour hour 24 monitoring checkups, checkups check ups, ups check-ups week sessions nutritionist members Comments response wellbeing. wellbeing well being. being well-being crucial

Abstract Introduction: Monochorionic monoamniotic (MCMA) pregnancy accounts for 1% of multiple pregnancies, with two fetuses sharing a placenta and amniotic cavity, representing a high obstetric risk pregnancy. Objective: To describe characteristics and perinatal outcomes of MCMA pregnancies, monitored, managed, and resolved according to the ultrasound follow-up protocol. Method: Observational, longitudinal, retrospective study, including all patients with MCMA pregnancies, from August 2010 to April 2022, monitored and evaluated at public hospital. Results: A total of 475 twin pregnancies; 1.3% MCMA pregnancies. Average maternal age 31.1 years (24-40), 50% primiparas. One case presented late miscarriage at 19 weeks, the remaining cases all delivered by cesarean section at 32.2 weeks (31-34). Average birth weight of 1,774 grams (1,150-2,050). Of the total pregnancies, 50% had two live twins at one year of age, 66.6% had two live twins at birth. Of the total fetuses: 17% late miscarriages, 8.3% stillbirths, and 8.3% neonatal deaths. Newborns hospitalized in neonatology had an average of 26 days (3-60). Conclusion: The management and follow-up of MCMA pregnancies is a significant challenge due to their high morbidity and mortality and potential complications. A multidisciplinary approach, applying standardized protocols, would be essential to ensure proper management.

Resumen Introducción: El embarazo monocorial monoamniótico (MCMA) corresponde al 1% de embarazos múltiples, dos fetos que comparten placenta y cavidad amniótica, lo que representa un embarazo de alto riesgo obstétrico. Objetivo: Describir características y resultados perinatales de gestaciones MCMA, controladas, manejadas y resueltas según protocolo de seguimiento ultrasonográfico. Método: Estudio observacional, longitudinal, retrospectivo, que incluyó a todas las pacientes con embarazos MCMA, de agosto de 2010 hasta abril de 2022, controladas y evaluadas en un hospital público. Resultados: Total de 475 gestaciones gemelares; 1,3% embarazos MCMA. Edad materna promedio 31,1 años (24-40), el 50% primigestas. Un caso presentó aborto tardío de 19 semanas, los restantes casos, todos partos vía cesárea a las 32,2 semanas (31-34). Promedio de peso al nacer de 1.774 gramos (1.150-2.050). Del total de embarazos, el 50% tenía dos gemelos vivos al año de vida, el 66,6% tenía dos gemelos vivos al parto. Del total de fetos: 17% abortos tardíos, 8,3% mortinatos y 8,3% mortineonatos. Recién nacidos hospitalizados en neonatología, promedio 26 días (3-60). Conclusión: El manejo y seguimiento del embarazo MCMA es un gran desafío, debido a su elevada morbimortalidad y complicaciones potenciales. Un enfoque multidisciplinario, aplicando protocolos estandarizados, sería esencial para garantizar un adecuado manejo.

Abstract Introduction: External cephalic version (ECV) allows to reduce the rate of cesarean sections due to breech presentation, with a variable success rate and without increasing obstetric complications, although it has been described that after successful ECV there could be a higher rate of intrapartum cesarean sec3ons as well as instrumental deliveries. Objective: To analyse results and factors associated with vaginal delivery after ECV, compared to delivery in patients with a spontaneously cephalic fetus. Method: Retrospective case-control study in patients with ECV performed in the same clinic. Each case was matched to a control. Demographic and clinical variables were analysed to determine maternal and neonatal outcomes as well as predictors of mode of delivery in successful ECV patients. Results: Four hundred fifty-eight ECV patients proposed were included, of which 276 (60.3%) were successful. Success was associated with multiparity, uterine relaxation and female fetal sex. Two hundred twenty-seven patients had a birth in our centre, who were matched with 229 controls. The ECV group had a higher rate of cesarean sections (23.3 vs. 15.3%; p = 0.03). Dystocia was the most frequent indication in both groups. Conclusions: ECV is a safe technique with a high success rate and good results, but once a successful version is achieved, the patient has a higher cesarean section rate attributable to any indication. Other obstetric were similar to patients with a spontaneously cephalic presentation fetus.

Resumen Introducción: La versión cefálica externa (VCE) permite disminuir la tasa de cesáreas por presentación de nalgas, con tasa de éxito variable y sin aumentar las complicaciones obstétricas, aunque se ha descrito que tras VCE exitosa podría haber mayor tasa de cesáreas intraparto así como de partos instrumentales. Objetivo: Analizar resultados y factores relacionados con el parto vaginal tras VCE exitosa comparándolos con el parto en pacientes con feto espontáneamente en cefálica. Método: Estudio retrospectivo de casos y controles en pacientes con VCE realizada en un único centro. Se analizaron variables demográficas y clínicas para determinar resultados maternos, neonatales y predictores de tipo de parto en las pacientes de VCE exitosa. Resultados: Se incluyeron 458 pacientes con VCE, de las cuales 276 (60,3%) fueron exitosas. El éxito se asoció a multiparidad, relajación uterina y sexo fetal femenino. Tuvieron un parto en nuestro centro 227 pacientes. Se emparejaron con 229 controles. El grupo VCE tuvo mayor tasa de cesáreas (23,3 vs. 15,3%; p = 0,03). La distocia fue la indicación más frecuente en ambos grupos. Conclusiones: La VCE es una técnica segura con alta tasa de éxito y buenos resultados. Una vez se consigue una versión exitosa la paciente tiene mayor tasa de cesárea atribuible a cualquier indicación, siendo los demás resultados obstétricos similares a las pacientes con un feto espontáneamente en presentación cefálica.

Abstract Introduction: Baclofen is an agonist of GABA receptors in the central nervous system (CNS) whose effect is to reduce spasticity. The dose used in intrathecal baclofen pump therapy is up to 100 times lower than oral. There are reports of withdrawal syndrome in neonates exposed to baclofen in utero. Case presentation: The case of a 31-year-old patient with a history of spasticity secondary to neonatal hypoxia being managed with an intrathecal baclofen pump since 2012 is presented, who in 2023 had a pregnancy, cesarean section at 37+2 weeks of gestation under general anesthesia with no complications with favorable maternal-fetal outcomes. Discussion: It is necessary to evaluate the safety of the use of technologies such as intrathecal pumps in pregnancy, in this case with the use of baclofen with which we found multiple questions given the absence of randomized studies such as its possible teratogenic effect on the fetus and the possible syndrome of abstinence on the neonate, the present clinical case reports the use of this technology with favorable maternal-fetal outcomes and compares it with the cases reported in the literature, also finding possible related side effects. Conclusions: The information to date seems to demonstrate that the use of baclofen intrathecally during pregnancy is completely safe given its low plasma concentrations.

Resumen Introducción: El baclofeno es un agonista de los receptores GABA en el sistema nervioso central (SNC), cuyo efecto es la disminución de la espasticidad. La dosis utilizada en la terapia por bomba intratecal de baclofeno es de hasta 100 veces menor que por vía oral. Existen reportes de síndrome de abstinencia en neonatos expuestos a baclofeno en el útero. Presentación del caso: Se presenta el caso de una paciente de 31 años con antecedente de espasticidad secundaria a hipoxia neonatal en manejo con bomba intratecal de baclofeno desde el año 2012, quien en el 2023 cursó con embarazo. La paciente presentó cesárea a las 37+2 semanas de gestación, bajo anestesia general y sin complicaciones con desenlaces materno-fetales favorables. Discusión: Es necesario evaluar la seguridad del uso de tecnologías como bombas intratecales en el embarazo, ya que en este caso y con el uso de baclofeno se encontraron múltiples interrogantes dada la ausencia de estudios aleatorizados, así como su posible efecto teratogénico en el feto y el posible síndrome de abstinencia sobre el neonato. El presente caso clínico reporta el uso de esta tecnología con desenlace materno-fetales favorables y lo compara con los casos hallados en la literatura, encontrando además posibles efectos secundarios relacionados. Conclusiones: La información hasta la fecha parece demostrar que el uso de baclofeno vía intratecal durante el embarazo es completamente seguro, dadas sus bajas concentraciones en plasma.

Abstract This is a qualitative study that explores the perspectives and experiences of a group of Mexican women who experienced institutionalized childbirth care in the first and second waves of the COVID-19 pandemic. Through a semi-structured script, nine women who experienced childbirth care were interviewed between March and October 2020 in public and private hospitals in the city of San Luis Potosí, Mexico. Under the Grounded Theory analysis proposal, it was identified that the health strategies implemented during the pandemic brought with them a setback in the guarantee of humanized childbirth. Women described themselves as distrustful of the protocols that personnel followed to attend to their births in public sector hospitals and very confident in those implemented in the private sector. The intervention of cesarean sections without a clear justification emerged as a constant, as did early dyad separation. Healthcare personnel’s and institutions’ willingness and conviction to guarantee, protect and defend the right of women to experience childbirth free of violence remain fragile. Resistance persists to rethink childbirth care from a non-biomedicalizing paradigm. COVID19 COVID 19 COVID-1 semistructured semi structured script 202 Potosí Mexico proposal constant separation personnels s institutions fragile nonbiomedicalizing non biomedicalizing paradigm COVID1 1 COVID- 20 2

Resumen Estudio de tipo cualitativo que explora las perspectivas y experiencias de un grupo de mujeres mexicanas que vivieron la atención institucionalizada del parto en la primera y segunda ola de la pandemia por COVID-19. A través de un guión semiestructurado se entrevistó a nueve mujeres que vivieron la experiencia de la atención del parto entre marzo y octubre de 2020, en hospitales públicos y privados de la ciudad de San Luis Potosí, en México. Bajo la propuesta de análisis de la teoría fundamentada, se identificó que las estrategias sanitarias implementadas en el marco de la pandemia, trajeron consigo un retroceso en la garantía del parto humanizado, las mujeres se narraron desconfiadas en los protocolos que siguió el personal para la atención de sus partos en los hospitales del sector público y muy confiadas en los que se implementaron en el sector privado. La realización de cesáreas sin una justificación clara emergió como una constante, igual que la separación temprana de los binomios. Continúa frágil la disposición y el convencimiento del personal sanitario y las instituciones para garantizar, proteger y defender el derecho de las mujeres a vivir el parto libre de violencia. Persisten resistencias para repensar la atención del parto desde un paradigma no biomédicalizante. COVID19. COVID19 COVID 19. 19 COVID-19 2020 Potosí México fundamentada humanizado privado constante binomios garantizar violencia biomédicalizante COVID1 1 COVID-1 202 COVID- 20 2

Resumo O artigo apresenta uma análise do desempenho da APS no estado de São Paulo na última década, em contexto de crise econômica e retração dos investimentos em saúde. Utilizaram-se indicadores de desempenho, determinantes em saúde e sistema de saúde, em série temporal (2010 a 2019), a partir de matriz conceitual adaptada. Foram calculadas variações percentuais anuais (VPA) de cada indicador em modelo log-linear. Os indicadores de desempenho apresentaram, no geral, evolução favorável; no entanto, ocorreu piora em indicadores relacionados à qualidade do cuidado (sífilis congênita, partos cesáreos e rastreamento de câncer de colo uterino). Verificou-se, ainda, um potencial aumento das demandas ao SUS (envelhecimento da população e redução da cobertura da saúde suplementar) e aumento das despesas em saúde em contexto de redução do PIB per capita.

Abstract This article presents the results of an analysis of the performance of primary health care in São Paulo state over the last decade against a backdrop of financial crisis and health funding cuts. We conducted a time series analysis (2010-2019) of performance indicators across the following dimensions based on an adapted conceptual framework: health service performance, health system, and determinants of health. Annual percentage change was calculated for each indicator using a log-linear model. Performance across the indicators was generally positive; however, there was a decline in performance across indicators of quality of care (congenital syphilis, cesarean section rate and cervical cancer screening). The findings also show a potential rise in demand for public services (due to population aging and a reduction in the percentage of the population with private health insurance) and increase in health expenditure against a backdrop of falling GDP per capita.

Abstract Primary hyperparathyroidism (PHPT) is characterized by elevated levels of calcium and parathyroid hormone (PTH). However, the interpretation of diagnostic tests, such as serum calcium and PTH levels, is complex in pregnant women. The aim of this report is to present a case of PHTP in a pregnant adolescent, with a special emphasis on an uncommon complication, as well as diagnostic and treatment strategies. A 17-year-old pregnant female presented with hyper emesis gravidarum and neurological symptoms, leading to the diagnosis of cerebral venous thrombosis. Further investigations revealed hypercalcemia and persistently elevated PTH levels, consistent with PHPT. After local ization studies, the patient underwent an emergency parathyroidectomy with a diagnosis of parathyroid ad enoma. During follow-up, intrauterine growth restric tion and severe preeclampsia developed, necessitating an emergency cesarean section. Both the mother and neonate had favorable outcomes. PHPT is an infrequent condition in the pregnant population, and its diagnosis can be challenging due to the overlap of symptoms with normal physiological changes during pregnancy. The occurrence of uncom mon complications, such as thrombotic phenomena, highlights the need for a comprehensive approach to ensure early detection and management. In most cases, parathyroidectomy is the treatment of choice.

Resumen El hiperparatiroidismo primario (HPTP) se caracteriza por niveles elevados de calcio y hormona paratiroidea (PTH). Sin embargo, la interpretación de pruebas diag nósticas, como los niveles de calcio sérico y PTH, es compleja en mujeres embarazadas. El objetivo de este re porte es presentar un caso de HPTP en una adolescente embarazada, con especial hincapié en una complicación infrecuente, así como en las estrategias diagnósticas y de tratamiento. Una mujer embarazada de 17 años presentó hiperé mesis gravídica y síntomas neurológicos, lo que llevó al diagnóstico de trombosis venosa cerebral. Posterio res investigaciones revelaron hipercalcemia y niveles persistentemente elevados de PTH, consistentes con HPTP. Tras la realización de estudios de localización, la paciente fue sometida a una paratiroidectomía de emergencia con diagnóstico de adenoma de paratiroi des. Durante el seguimiento, se desarrolló restricción del crecimiento intrauterino y preeclampsia grave, lo que resultó en la necesidad de realizar una cesárea de emergencia. Tanto la madre como el neonato evolucio naron favorablemente. El HPTP es una condición infrecuente en la población embarazada y su diagnóstico puede ser desafiante por la superposición de síntomas con los cambios fisiológicos normales del embarazo. La aparición de complicaciones infrecuentes, como fenómenos trombóticos, resalta la necesidad de un abordaje integral para garantizar la detección y el manejo temprano. En la mayoría de los casos, la paratiroidectomía es el tratamiento de elección.

Abstract Introduction: According to the Organisation for Economic Co-operation and Development, Chile has one of the highest caesarean section rates on the continent, reaching 44.7% in 20132 and 47.7% in 20173 , ranking third only to Turkey and Mexico. Objective: Analyze the factors related to cesarean section intervention in women who delivered in a private clinic in the Fifth Region of Chile, from 2018 to 2022. Method: Cross-sectional study involving 9,041 users. A logistic regression model with odds ratio and its 95% confidence intervals was used to assess associations with sociodemographic and obstetric factors. Results: The prevalence of cesarean section during the study period was 85.1%. Primiparous status, previous cesarean section, presence of maternal and fetal pathology, absence of labor and surgical sterilization were associated with an increased likelihood of cesarean section, while gestational age 36 and under weeks showed a decreased chance. Conclusions: A high prevalence of cesarean sections stands out for the study period, higher than that reported in the literature.

Resumen Introducción: De acuerdo con lo reportado por la Organización para la Cooperación y el Desarrollo Económico, Chile posee una de las tasas más altas de cesárea para el continente, llegando a un 44,7% en 2013 y un 47,7% en 2017, ubicándose en tercer lugar, solo precedido por Turquía y México. Objetivo: Analizar los factores relacionados a intervención de cesárea en las mujeres que atendieron su parto en una clínica privada de la Quinta Región de Chile entre los años 2018 y 2022. Método: Estudio transversal analítico en 9041 usuarias. Se utilizó un modelo de regresión logística con odds ratio y sus intervalos de confianza del 95% para evaluar la asociación con variables sociodemográficas y obstétricas. Resultados: La prevalencia de cesárea fue del 85,1% en el periodo estudiado. La condición de gestante primípara, la cesárea previa, la presencia de patología materna o fetal, la ausencia de trabajo de parto y la esterilización quirúrgica presentaron mayor probabilidad de cesárea, mientras que para la edad gestacional, menor o igual a 36 semanas, ésta fue menor. Conclusiones: Destaca un alta prevalencia de cesáreas para el periodo de estudio, superior a lo reportado en la literatura.

Abstract: Introduction: Opiates and benzodiazepines are the ones that most frequently produce withdrawal syndrome. Objective: Know the risk factors associated with abstinence syndrome in patients whit sedoanalgesia. Material and methods: Prospective, longitudinal, analytical; newborns received sedoanalgesia with fentanyl and midazolam for more than 24 hours. The clinical-demographic association with abstinence syndrome was analyzed using the Finnegan scale. Test t-Student, Mann-Whitney U and Mann-Whitney, χ2 for differences in different variables, logistic regression the independent variables associated with abstinence syndrome, alpha level < 0.05, SPSS v.23.0 program. Results: 84 patients, 56% male, predominated means: weeks of gestation 35 ± 3.8, weight 2,350 ± 866 g and cesarean 65.5%. To the Finnegan scale 7.1% file abstinence syndrome which 66.7% was mild and 33.3% moderate; the association between the presence of abstinence syndrome is found: cesarean, maternal age of 30 years, male, first or second gestation, 38 weeks gestation (p ≤ 0.01), weighing greater than 2,700 g, diagnosed with post-surgical admission and mechanical ventilation. Conclusion: There is a relationship between clinical demographic variables in newborn patients receiving sedoanalgesia and the presentation of with abstinence syndrome; however further studies are required to establish and adopt preventive measures.

Resumen: Introducción: Opiáceos y benzodiacepinas producen síndrome de abstinencia con mayor frecuencia. Objetivo: Conocer los factores de riesgo asociados al síndrome de abstinencia en pacientes con sedoanalgesia. Material y métodos: Prospectivo, longitudinal, analítico, recién nacidos con sedoanalgesia fentanilo y midazolam más de 24 horas. Analizamos la asociación clínico-demográfica con síndrome de abstinencia mediante la escala de Finnegan. Utilizamos test t-Student, U de Mann-Whitney, χ2 para diferencias de distintas variables, regresión logística para variables independientes que se asociaron al síndrome de abstinencia, alfa < 0.05, programa SPSS v.18. Resultados: Ochenta y cuatro pacientes, 56% hombres, 35 ± 3.8 semanas de gestación, peso 2,350 ± 866 g, cesárea 65.5%. De la escala de Finnegan, 7.1% presentó síndrome de abstinencia; de los cuales, 66.7% fue leve y 33.3% moderado, encontrándose asociación: cesárea, edad materna 30 años, masculino, primera o segunda gesta, 38 semanas de gestación (p ≤ 0.01), peso mayor a 2,700 g, diagnóstico de ingreso postquirúrgico y ventilación mecánica. Conclusión: Existe relación entre variables clínico demográficas en pacientes recién nacidos que reciben sedoanalgesia y la presentación del síndrome de abstinencia; sin embargo, se requieren mayores estudios para establecer y adoptar medidas de prevención.

Abstract: We report the anesthetic management of a parturient with Takayasu arteritis and several comorbidities scheduled for elective cesarean section with the authorization of the institutional ethics committee. A two-segment combined spinal-epidural technique was used to provide anesthesia with close control of invasive arterial pressure and the use of Norepinephrine endovenous infusion. Likewise, a literature review of the two-segment combined technique for cesarean section in pregnant women with this disease was performed.

Resumen: Reportamos el manejo anestésico de una gestante con múltiples comorbilidades debido a arteritis de Takayasu programada para cesárea electiva con la autorización del comité de ética institucional. Se utilizó una técnica combinada espinal-epidural en dos segmentos para suministrar anestesia con la titulación estricta de la presión arterial invasiva y el uso de una infusión endovenosa de norepinefrina. Asimismo, se realizó una revisión sobre el uso de la técnica combinada en dos segmentos para cesárea en gestantes con esta enfermedad.

Abstract Uterine niche is a recess located in the anterior wall of the uterine isthmus, over the cesarean section scar. This condition is often asymptomatic, but it can be associated with symptoms such as abnormal uterine bleeding, pelvic pain and secondary infertility. Endovaginal ultrasound is the first-line diagnostic method. Treatment includes hormonal methods or surgery, and surgical treatment seems to be the most effective in resolving symptoms. We describe the case of a 37-year-old woman, with an obstetric history of a pregnancy with cesarean delivery, who complained of pelvic pain and menstrual irregularity. An endovaginal ultrasound was requested, which reported the presence of a “… echogenic oval formation with well-defined limits measuring 28x17 mm in the topography of the cesarean scar.” After a clinical discussion with a doctor specializing in Gynecology, the patient was referred to a hospital consultation in this specialty for investigation. The diagnosis of uterine niche was confirmed, and the treatment consisted of the placement of an intrauterine system.

Resumo Nicho uterino é um recesso localizado na parede anterior do istmo uterino, sobre a cicatriz de cesariana. Frequentemente esta condição é assintomática, mas pode estar associada a sintomas como hemorragia uterina anómala, dor pélvica e infertilidade secundária. A ecografia endovaginal é o método diagnóstico de primeira linha. O tratamento inclui métodos hormonais ou cirurgia, sendo que o tratamento cirúrgico parece ser o mais eficaz na resolução dos sintomas. Descrevemos o caso de uma mulher de 37 anos, com antecedentes obstétricos de uma gestação com parto por cesariana que apresentava queixas de dor pélvica e irregularidade menstrual. Foi solicitada ecografia endovaginal que relatou a presença de uma “…formação ovalada ecogénica de limites bem definidos com 28x17 mm na topografia da cicatriz de cesariana.” Após discussão clínica com médico especialista em Ginecologia, a doente foi encaminhada para consulta hospitalar desta especialidade para investigação, tendo sido confirmado o diagnóstico de nicho uterino e cujo tratamento consistiu na colocação de sistema intrauterino.

Resumo O artigo apresenta uma análise do desempenho da APS no estado de São Paulo na última década, em contexto de crise econômica e retração dos investimentos em saúde. Utilizaram-se indicadores de desempenho, determinantes em saúde e sistema de saúde, em série temporal (2010 a 2019), a partir de matriz conceitual adaptada. Foram calculadas variações percentuais anuais (VPA) de cada indicador em modelo log-linear. Os indicadores de desempenho apresentaram, no geral, evolução favorável; no entanto, ocorreu piora em indicadores relacionados à qualidade do cuidado (sífilis congênita, partos cesáreos e rastreamento de câncer de colo uterino). Verificou-se, ainda, um potencial aumento das demandas ao SUS (envelhecimento da população e redução da cobertura da saúde suplementar) e aumento das despesas em saúde em contexto de redução do PIB per capita. década Utilizaramse Utilizaram se 2010 (201 2019, 2019 , 2019) adaptada VPA (VPA loglinear. loglinear log linear. linear log-linear apresentaram geral favorável entanto sífilis congênita uterino. uterino . uterino) Verificouse, Verificouse Verificou se, Verificou-se ainda envelhecimento suplementar capita 201 (20 20 (2 2 (

Abstract This article presents the results of an analysis of the performance of primary health care in São Paulo state over the last decade against a backdrop of financial crisis and health funding cuts. We conducted a time series analysis (2010-2019) of performance indicators across the following dimensions based on an adapted conceptual framework: health service performance, health system, and determinants of health. Annual percentage change was calculated for each indicator using a log-linear model. Performance across the indicators was generally positive; however, there was a decline in performance across indicators of quality of care (congenital syphilis, cesarean section rate and cervical cancer screening). The findings also show a potential rise in demand for public services (due to population aging and a reduction in the percentage of the population with private health insurance) and increase in health expenditure against a backdrop of falling GDP per capita. cuts 20102019 2010 2019 (2010-2019 framework system loglinear log linear model positive however congenital syphilis screening. screening . screening) due insurance capita 2010201 201 (2010-201 201020 20 (2010-20 20102 2 (2010-2 (2010- (2010 (201 (20 (2 (