Abstract Adolescent idiopathic scoliosis is considered the most severe and common spinal deformity, affecting children and adolescents still in the neuropsychomotor development phase before they reach skeletal maturity. This study aimed to evaluate the surgical approach to adolescent idiopathic scoliosis (AIS), considering the results associated with the reduction of pathological curvature, pulmonary function, and repercussions on the quality of life of adolescents undergoing such treatment. Systematic literature review, with a quantitative and qualitative approach to the data collected, structured according to the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA), carried out in the databases linked to the Medical Literature Analysis and Retrieval System Online (MEDLINE) and Latin American and Caribbean Health Sciences Literature (LILACS). The total sample of the studies was 638 adolescents with AIS, with a mean age of 14.93 years ± 1.24. The mean correction of the main pathological curvature in the studies was 55.06% ± 12.24. In all of the selected studies using posterior spinal fusion to correct AIS, there was a significant reduction in pathological curvatures (> 49%), and the recurrence of curvature in none of the studies exceeded a pathological gain of more than 5%. As for lung function, the studies showed significant increases in forced expiratory volume in 1 second (FEV1) and forced vital capacity (FVC) in patients with severe AIS, and no pulmonary function losses were reported after surgery to correct AIS. deformity maturity AIS , (AIS) treatment review collected MetaAnalyses Meta Analyses PRISMA, PRISMA (PRISMA) MEDLINE (MEDLINE LILACS. LILACS . (LILACS) 63 1493 14 93 14.9 124 24 1.24 5506 55 06 55.06 1224 12 12.24 > ( 49%, 49 49% 49%) 5 5% FEV1 FEV (FEV1 FVC (FVC (AIS (PRISMA (LILACS 6 149 9 14. 2 1.2 550 0 55.0 122 12.2 4 (FEV 1. 55. 12.

Resumo A escoliose idiopática do adolescente (EIA) é considerada a deformidade vertebral de maior gravidade e ocorrência, que acomete crianças e adolescentes ainda na fase de desenvolvimento neuropsicomotor, antes de atingirem a maturidade esquelética. Este estudo teve como objetivo avaliar a abordagem cirúrgica da EIA, considerando resultados associados à redução de curvatura patológica, função pulmonar e repercussões na qualidade de vida dos adolescentes submetidos a tal tratamento. Revisão Sistemática de literatura, com abordagem quanti-qualitativa dos dados coletados, cuja estruturação se deu conforme as orientações de Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) realizada nas bases de dados vinculadas à Medical Literature Analysis and Retrieval System Online (MEDLINE) e Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS). A amostra total dos estudos foi de 638 adolescentes com EIA, com uma idade média de 14,93 anos ± 1,24. A correção média da curvatura patológica principal nos estudos foi de 55,06% ± 12,24. Em todos os estudos selecionados com fusão espinhal posterior para correção da EIA verificou-se redução significativa das curvaturas patológicas (> 49%), sendo que a reincidência de curvatura em nenhum dos estudos superou um ganho patológico superior a 5%. Quanto à função pulmonar, os estudos apontaram ganhos significativos de volume expiratório forçado em 1 segundo (VEF1) e capacidade vital forçada (CVF) em pacientes com EIA grave. Além disso, não foram relatados prejuízos de função pulmonar após intervenção cirúrgica para correção da EIA. (EIA ocorrência neuropsicomotor esquelética tratamento literatura quantiqualitativa quanti qualitativa coletados MetaAnalyses Meta Analyses PRISMA (PRISMA MEDLINE (MEDLINE LatinoAmericana Latino Americana LILACS. LILACS . (LILACS) 63 1493 14 93 14,9 124 24 1,24 5506 55 06 55,06 1224 12 12,24 verificouse verificou > ( 49%, 49 49% , 49%) 5 5% VEF1 VEF (VEF1 CVF (CVF grave disso (LILACS 6 149 9 14, 2 1,2 550 0 55,0 122 12,2 4 (VEF 1, 55, 12,

ABSTRACT Foundation: hypertension has become one of the most prevalent conditions among Cuban adults and the main risk factor for morbidity and mortality due to cardiovascular causes. Objective: to evaluate the impact of the implementation of the Arterial Hypertension Program Based on the HEARTS Initiative in the Octavio de la Concepción y de la Pedraja Community Polyclinic in the Cienfuegos municipality. Methods: a descriptive, cross-sectional study was carried out in health systems and services from 2018 to 2022. The universe was the population over 18 years of age and the sample of 4,346 hypertensive patients. The variables were studied: sex, control of high blood pressure, technological structure, performance index, maturity index and mortality behavior due to cardiovascular diseases. Results: the performance index of the Basic Health Teams was excellent and the maturity index was in the advanced category. 85.5 % diagnostic and registration coverage were achieved, 94.7 % control among treated patients, 39.5 % control of patients with high cardiovascular risk and 60.1 % population control. Mortality from cardiovascular diseases for all ages, specifically premature mortality, decreased, with a predominance of the male sex. Conclusions: the implementation of the arterial hypertension program consolidated a work system for the improvement of action in Primary Health Care for hypertensive patients. The use of standardized therapeutic policy has had an impact on blood pressure control.

RESUMEN Fundamento: la hipertensión se ha convertido en una de las condiciones de mayor prevalencia entre los adultos cubanos y en el principal factor de riesgo de morbilidad y de mortalidad por causas cardiovasculares. Objetivo: evaluar el impacto de la implementación del Programa de Hipertensión Arterial basado en la Iniciativa HEARTS en el Policlínico Comunitario Octavio de la Concepción y de la Pedraja en el municipio Cienfuegos. Métodos: se realizó un estudio descriptivo, de corte transversal en sistemas y servicios de salud desde el 2018 hasta el 2022. El universo fue la población mayor de 18 años y la muestra de 4 346 hipertensos. Se estudiaron las variables: sexo, control de hipertensión arterial, estructura tecnológica, índice de desempeño, índice de madurez y comportamiento de la mortalidad por enfermedades cardiovasculares. Resultados: el índice de desempeño de los Equipos Básicos de Salud fue excelente y el índice de madurez tuvo la categoría de avanzado. Se alcanzó el 85,5 % de cobertura diagnóstica y de registro, el 94,7 % de control entre tratados, un 39,5 % de control de los pacientes con alto riesgo cardiovascular y el 60,1 % de control poblacional. La mortalidad por enfermedades cardiovasculares para todas las edades en específico la mortalidad prematura disminuyó, con predominio del sexo masculino. Conclusiones: la implementación del programa de hipertensión arterial consolidó un sistema de trabajo para el perfeccionamiento de actuación en la Atención Primaria de Salud ante el paciente hipertenso. El uso de la política terapéutica estandarizada ha tenido impacto en el control de la presión arterial.

ABSTRACT The concentration of linoleic and α-linolenic fatty acids (FA) in grasses can be increased through agronomic techniques; however, there is little information in this regard for tropical grasses. Therefore, the objective of the study was to evaluate the effect of N fertilization and regrowth age management on the FA profile of three tropical grasses. To do this, three plots of 100 m2 each were used for the species: Urochloa decumbens (Stapf) R.D. Webster, U. humidicola (Rendle) Morrone & Zuloaga, and Megathyrsus maximus (Jacq.) B.K. Simon & S.W.L. Jacobs. The study was conducted during dry and rainy seasons. In each period, they were divided into two subplots and only one of them was fertilized. Grass sampling was carried out on days 20, 25, and 30 after fertilization. Five samples were taken from each subplot and an agronomic evaluation was made before each cut. The chemical composition and lipid profile were then determined. An ANOVA of a randomized complete block design with split plot arrangement was performed. The concentration of linoleic and α-linolenic acid was higher in M. maximus during drought (48.5 g 100 g-1 FA) and in U. humidicola during the rainy season (55.1 g 100 g-1 FA). This proportion was higher on day 20 (50.5 g 100 g-1 FA) compared to that recorded on days 25 and 30 (50.1 and 45.7 g 100 g-1 FA, respectively). The fertilized grasses had a higher concentration of linoleic and α-linolenic acid compared to the unfertilized ones (53.4 vs. 44.3 g 100 g-1 FA). It is concluded that fertilization with 50-20-00 (N-P-K) increases the proportion of linoleic and α-linolenic acids in grasses; however, such concentration decreases with increasing plant maturity.

ABSTRACT: When applied at growing phase, lighting program aims to obtain quails with body weight and physiological maturity suitable for the beginning of laying. This study evaluated lighting programs at growing phase on performance, sexual maturity and egg quality of meat quail breeders (Coturnixcoturnix) at laying phase. From 7 to 49 days of age, 300 female meat quails were subjected to three lighting programs (natural, intermittent and continuous), with 5 replicates of 20 birds each. At 49 days of age, 240 quails were transferred to a shed, maintaining the same experimental conditions. Meat quails submitted to continuous and intermittent lighting programs had higher weight of reproductive system and lower ages for first egg production and to reach 50% of egg production (P < 0.05). Quails submitted to natural lighting had lower feed intake from 49 to 70 and 71 to 92 days of age and worse feed conversion up to 114 days of age. Continuous and intermittent lighting programs resulted in more precocious quails compared to natural lighting program. Quails submitted to natural lighting at growing phase presented lower egg production during all periods, not differing for birds submitted to continuous and intermittent programs from the second period (71 to 92 days of age). Intermittent and continuous lighting result in better feed conversion of breeding quails up to 114 days and a higher percentage of laying (49 to 136 days), reducing the number of days to produce the first egg and to reach 50% of laying, in relation to natural lighting. ABSTRACT performance Coturnixcoturnix (Coturnixcoturnix 4 30 natural, (natural continuous, , continuous) 2 each 24 shed conditions 50 P 0.05. 005 0.05 . 0 05 0.05) 9 11 periods (7 age) (4 13 days, days) 3 00 0.0 1 ( 0.

RESUMO: Quando aplicado na fase de crescimento, o programa de luz visa obter codornas com peso corporal e maturidade fisiológica adequados para o início da postura. Este estudo avaliou programas de iluminação na fase de crescimento sobre o desempenho, maturidade sexual e qualidade dos ovos de codornas de corte reprodutoras (Coturnix coturnix) na fase de postura. Durante o período de sete a 49 dias de idade, 300 codornas de corte fêmeas foram submetidas a três programas de iluminação (natural, intermitente e contínuo), com cinco repetições de 20 aves cada. Aos 49 dias de idade, 240 codornas foram transferidas para um galpão, mantendo a mesma distribuição experimental e submetidas às mesmas condições. As aves submetidas aos programas de iluminação contínuo e intermitente na fase de crescimento apresentaram maiores peso relativo do sistema reprodutivo e consequentemente menores idades para produção do primeiro ovo e para atingir 50% da produção de ovos (P < 0.05). As aves que receberam apenas iluminação natural apresentaram menor consumo de ração nos períodos de 49 a 70 e 71 a 92 dias de idade e pior conversão alimentar até 114 dias de idade. Os programas de iluminação contínua e intermitente na fase de crescimento resultaram em codornas mais precoces quando comparados as aves submetidas ao programa de iluminação natural. Codornas submetidas a programa de luz natural na fase de crescimento apresentaram menor produção de ovos durante todos os períodos, não diferindo das aves submetidas a programas contínuos e intermitentes a partir do segundo período (71 a 92 dias de idade). A iluminação intermitente e contínua na fase de crescimento resulta em melhor conversão alimentar de codornas reprodutoras até 114 dias e maior percentual de postura (49 a 136 dias), reduzindo o número de dias para produzir o primeiro ovo e atingir 50% de postura, em relação a iluminação natural.. RESUMO desempenho Coturnix coturnix 4 30 natural, (natural contínuo, , contínuo) 2 cada 24 galpão condições 50 P 0.05. 005 0.05 . 0 05 0.05) 7 9 11 (7 idade) (4 13 dias, dias) 3 5 00 0.0 1 ( 0.

ABSTRACT: This study estimated the growth of body, carcass, primal cuts, edible offal, and feathers of Japanese quail reared in two thermal environments, receiving three nutritional plans, from one to 39 days of age. A total of 576 one-day-old female chicks (Coturnix japonica) with an average initial weight of 7.51±0.75g/bird were evaluated in a completely randomized design with a 3 × 2 factorial arrangement (three nutritional plans × two temperatures). The animals were housed in two climatic chambers, at 25 ºC and 35 ºC, using 12 replications with eight birds per experimental unit. Nutritional plans (NP) were as follows: NP1: one diet from 1-21days and another from 22-39 days; NP2: one diet from 1-14 days and another from 15-39 days; and NP3: a single diet from 1-39 days. The growth curves and growth rates of body, carcass, primal cuts, feathers, and edible offal were evaluated using the Gompertz mathematical model. Quail fed NP3 showed higher growth curves and rates for body, carcass, drumstick +thigh, and feather. There was an effect on maturity rate, which was lowest in quail housed at 35 ºC. Among the animals kept at 25 ºC, the group fed NP3 exhibited the highest growth rate and breast weight. The nutritional plan consisting of a single diet offered from 1 to 39 days, formulated based on the tables for Japanese and European quail, is the most suitable for estimating the growth curves (Gompertz model) of Japanese quail housed at 25 ºC or 35 ºC. ABSTRACT body carcass cuts environments age 57 onedayold day old Coturnix japonica 751075gbird gbird 7 51 0 75g bird g temperatures. temperatures . temperatures) chambers unit NP (NP follows NP1 121days 21days 2239 22 22-3 NP2 114 14 1-1 1539 15 15-3 139 1-3 model thigh +thigh feather 5 223 22- 11 1- 153 15- 13

RESUMO: Objetivou-se estimar o crescimento corporal, carcaça, cortes nobres, vísceras comestíveis e penas de codornas japonesas criadas em dois ambientes térmicos e alimentadas com três planos nutricionais de um a 39 dias. Foram utilizadas 576 pintainhas (Coturnix japônica), fêmeas, com um dia de idade, com peso médio inicial 7,51 ± 0,75g/ave, distribuídas em delineamento inteiramente casualizado em esquema fatorial 3 × 2 (três planos nutricionais x duas temperaturas), alojadas em duas câmaras climáticas de 25º e 35 ºC, com 12 repetições e oito aves por unidade experimental. Os planos nutricionais foram: plano nutricional um (PN1) - uma dieta de 1-21 dias e uma dieta de 22-39 dias; plano nutricional dois (PN2) - uma dieta de 1-14 dias e uma dieta de 15-39 dias; e plano nutricional três (PN3) - dieta única de 1-39 dias. Foram avaliadas as curvas e taxas de crescimento corporal, carcaça, cortes nobres, penas e vísceras comestíveis, através do modelo matemático de Gompertz. Codornas alimentadas com PN3 apresentaram maiores curvas e taxas de crescimento corporal, de carcaça, coxa + sobrecoxa e penas. Houve efeito para taxa de maturidade, sendo inferior para codornas alojadas em 35 ºC. Nas aves mantidas em 25 ºC, observou-se maior taxa de crescimento e peso de peito nas codornas alimentadas com PN3. O plano nutricional composto por uma única dieta ofertada durante o período de um a 39 dias, formulado com base nas recomendações das tabelas para codornas japonesas e europeias, é o mais indicado para estimar curvas de crescimento no modelo de Gompertz de codornas japonesas alojadas em 25 ºC ou 35 ºC. RESUMO Objetivouse Objetivou se corporal carcaça nobres 57 Coturnix japônica, japônica , japônica) fêmeas idade 751 7 51 7,5 075gave gave 0 75g ave g 0,75g/ave temperaturas, temperaturas temperaturas) º 1 experimental foram PN1 PN (PN1 121 21 1-2 2239 22 22-3 PN2 (PN2 114 14 1-1 1539 15 15-3 (PN3 139 1-3 maturidade observouse observou europeias 5 75 7, (PN 1- 223 22- 11 153 15- 13

ABSTRACT Objective: To estimate the serum levels of non-radiologic biomarkers, Insulin-like Growth Factor-1 (IGF-1), and Insulin-like Growth Factor Binding Protein-3 (IGFBP-3) to potentially identify the pubertal growth spurt in skeletal Class II malocclusion subjects. Material and Methods: Eighty subjects (M-38, F-42) with skeletal Class II malocclusion in the age range of 11-18 years were recruited for the cross-sectional study. Human serum IGF-1 and IGFBP-3 were quantitatively assessed by enzyme-linked immunosorbent assay, and the cervical stage (CS) was evaluated from a lateral cephalogram. Results: Gender-wise comparison of the mean serum IGF-1 levels revealed that the initial peak was detected at CS2 in both genders, [males (87.87 ng/mL), females (78.49 ng/mL)]. However, there was a cognizable difference in the second peak of the mean serum IGF-1 levels between males (CS5, 68.58 ng/mL) and females (CS4, 74.63 ng/mL). Mean IGFBP-3 serum levels in male subjects were high in CS4 (47.24 ng/mL) with a further spike in CS6 (50.54 ng/mL), and in female subjects, it was found to be highest in CS3 (51.95 ng/mL) and then in CS5 (49.68 ng/mL). Conclusion: Mean IGF-1 levels exhibited both sexes' prepubertal and late pubertal spikes. Mean IGFBP-3 levels revealed a pubertal and a late pubertal spike in both sexes, with an earlier growth trend observed specific to females compared to males. Objective nonradiologic non radiologic biomarkers Insulinlike Insulin like Factor1 1 Factor- IGF1, IGF1 IGF , (IGF-1) Protein3 Protein 3 Protein- IGFBP3 IGFBP (IGFBP-3 Methods M38, M38 M 38, 38 (M-38 F42 F 42 F-42 1118 11 18 11-1 crosssectional cross sectional study IGF- IGFBP- enzymelinked enzyme linked assay CS (CS cephalogram Results Genderwise Gender wise genders 87.87 8787 87 (87.8 ng/mL, ngmL ng/mL ng mL 78.49 7849 78 49 (78.4 ng/mL. . ng/mL)] However CS5, (CS5 6858 68 58 68.5 CS4, (CS4 7463 74 63 74.6 47.24 4724 47 24 (47.2 50.54 5054 50 54 (50.5 51.95 5195 51 95 (51.9 49.68 4968 (49.6 Conclusion sexes spikes (IGF-1 (IGFBP- M3 (M-3 F4 4 F-4 111 11- 87.8 878 8 (87. 78.4 784 7 (78. 685 6 5 68. 746 74. 47.2 472 2 (47. 50.5 505 (50. 51.9 519 9 (51. 49.6 496 (49. (IGF- (IGFBP (M- F- 87. (87 78. (78 47. (47 50. (50 51. (51 49. (49 (IGF (M (8 (7 (4 (5 (

Abstract: This paper examines how digitalization of Micro, Small, and Medium Enterprises (MSMEs) is influenced by their ability to adapt in a turbulent environment. Our goal is to understand the role of dynamic capabilities, specifically sensing and seizing opportunities, in the digital maturity of firms. We employ a structural equation model to analyze the effect of these capabilities on MSMEs’ digitalization, taking advantage of a novel data set from the self-assessment tool Chequeo Digital in Ecuador. Our focus on dynamic capabilities in the MSMEs context, represents a significant contribution, enhancing our understanding of the determinants of digitalization. The results show a positive and substantial effect of both capabilities on the digital advance of MSMEs. Moreover, we found a negative and significant moderating effect of firm age, on the relationship between sensing capability and digitalization, suggesting that older firms may face in adopting digital technologies when compared to their younger counterparts.

ABSTRACT Congenital heart disease (CHD) affects eight to ten out of every 1,000 births, resulting in approximately 23,057 new cases in Brazil in 2022. About one in four children with CHD requires surgery or other procedures in the first year of life, and it is expected that approximately 81% of these children with CHD will survive until at least 35 years of age. Professionals choosing to specialize in CHD surgery face numerous challenges, not only related to mastering surgical techniques and the complexity of the diseases but also to the lack of recognition by medical societies as a separate subspecialty. Furthermore, families face difficulties when access to services capable of providing treatment for these children. To address these challenges, it is essential to have specialized hospitals, qualified professionals, updated technologies, sustainable industry, appropriate financing, quality assessment systems, and knowledge generation. The path to excellence involves specialization across all involved parties. As we reflect on the importance of Pediatric Cardiovascular Surgery and Congenital Heart Diseases establishing themselves as a subspecialty of Cardiovascular Surgery, it is essential to look beyond our borders to countries like the United States of America and United Kingdom, where this evolution is already a reality. This autonomy has led to significant advancements in research, education, and patient care outcomes, establishing a care model. By following this path in Brazil, we not only align our practice with the highest international standards but also demonstrate our maturity and the ability to meet the specific needs of patients with CHD and those with acquired childhood heart disease. (CHD 1000 1 000 1,00 births 23057 23 057 23,05 2022 life 81 3 age challenges Furthermore hospitals professionals technologies industry financing systems generation parties Kingdom reality research education outcomes model 100 00 1,0 2305 2 05 23,0 202 8 10 0 1, 230 23, 20

ABSTRACT Consumer preference and acceptance surveys associated with genetic improvement programs contribute to greater acceptance of new cultivars, in the competitive and dynamic ornamental plants market. Thus, the present work aimed to evaluate Brazilian habits related to the home cul-tivation of Capsicum spp. and preferences regarding four pre-cultivars of ornamental pepper, and the relationship with different socioeconomic factors. A virtual questionnaire containing 18 multiple-choice questions was shared by the authors in their contact networks, via social media and email. The responses were analyzed using descriptive statistics. The influence of socioeconomic factors on the respondents' habits and preferences was analyzed using the Chi-Square test. The survey included 1045 respondents from all Brazilian states, of all age groups, income levels and education levels. It was found that home cultivation of peppers is widespread throughout Brazil, in rural and urban areas, mostly in pots. Ornamental peppers were widely ac-cepted among men and women of all income classes. Although a greater preference was observed for white flowers and elongated, triangular fruits, with five stages of maturity, regional, social, and economic differences influenced the choice for these attributes. Greater acceptance was also observed for the medium vessel (2 dm3) and the hybrid HPO 03. After registration, this will be an important technological product adapted to Brazilian conditions. cultivars market Thus cul tivation spp precultivars pre pepper 1 multiplechoice multiple networks email statistics ChiSquare Chi Square test 104 states groups Brazil areas pots accepted ac cepted classes elongated fruits maturity regional attributes 2 ( dm3 dm 03 registration conditions 10 0

RESUMO No competitivo e dinâmico mercado de plantas ornamentais, pesquisas de preferência e aceitação dos consumidores associadas à programas de melhoramento genético cooperam para a maior aceitação de novas cultivares. Assim, o presente trabalho objetivou avaliar hábitos dos brasileiros relacionados ao cultivo doméstico de Capsicum spp. e preferências quanto à quatro pré-cultivares de pimenta ornamental, e a relação com diferentes fatores socioeconômicos. Questionário virtual contendo 18 perguntas de múltipla escolha foi compartilhado pelos autores em suas redes de contatos, via mídias sociais e e-mail. As respostas foram analisadas por meio de estatísticas descritivas. A influência dos fatores socioeconômicos em relação aos hábitos e preferências dos respondentes foi analisada pelo teste Qui-Quadrado. A pesquisa contemplou 1045 respondentes de todos os estados brasilei-ros, de todas as faixas de idade, níveis de renda e grau de escolaridade. Verificou-se que o cultivo doméstico das pimentas é bastante difundido em todo Brasil, em zonas rurais e urbanas, majoritariamente, em vasos. Pimentas ornamentais tiveram grande aceitação entre homens e mulheres de todas as classes de renda. Embora tenha sido observado maior preferência por flores brancas e frutos alongados e triangulares, com cinco estádios de maturação, diferenças regionais e sociais influenciaram a escolha por esses atributos. Maior aceitação também foi observada para o vaso médio (2 dm3) e para híbrido HPO 03. Após registro, este será um importante produto tecnológico adaptado às condições brasileiras. cultivares Assim spp précultivares pré ornamental 1 contatos email. email mail. mail e-mail descritivas QuiQuadrado. QuiQuadrado Qui Quadrado. Quadrado Qui-Quadrado 104 brasileiros, brasilei ros, ros brasilei-ros idade escolaridade Verificouse Verificou se Brasil urbanas majoritariamente vasos triangulares maturação atributos 2 ( dm3 dm 03 registro brasileiras 10 0

Abstract This review elucidates the physiological and endocrinological processes intrinsic to puberty and ovulation induction protocols in Bos indicus and Bos taurus beef heifers. Puberty is a complex physiological event involving gonadotropic and metabolic changes that lead to sexual maturity, first ovulation, and regular reproductive cycles, enabling females to reproduce. Exposure to progesterone-based hormonal protocols, with or without additional hormones, can reduce the age at first ovulation and improve sexual maturity through stimuli in the hypothalamus-pituitary-gonadal (HPG) axis and uterine development. However, inducing puberty differs from inducing ovulation, as it does not ensure the heifer will continue cycling or be ready to establish and maintain pregnancy after hormonal exposure. Regardless of the pharmacological basis, studies consistently report that beef heifers that had a corpus luteum (CL) prior to the timed-artificial insemination (TAI) protocol, have greater expression of estrus in response to synchronization and greater pregnancy per AI compared to heifers without a CL. The combination of P4 and E2 significantly impacts uterine development, increasing reproductive efficiency. Exposure to P4 causes a positive effect on inducing ovulation. However, studies indicate that the addition of E2 esters at the time of P4 device removal increases the ovulation rate. In general, the studies showed that fertility varied according to the type of the ovulation induction protocol used, but with inconsistent results. Although ovulation induction protocols are strategic tools to accelerate sexual maturity, a holistic view of the entire system is extremely important, combining integration with genetics and nutrition to enhance the reproductive outcomes of beef heifers. Future research is needed to understand and refine these protocols, driving the efficiency of beef cattle production systems. cycles reproduce progesteronebased progesterone based hormones hypothalamuspituitarygonadal hypothalamus pituitary gonadal HPG (HPG development However exposure basis CL (CL timedartificial timed artificial TAI (TAI P E rate general used results important systems

ABSTRACT Objective: Psychological maturity can be comprehended as a multifaceted construct encompassing various psychosocial, emotional, and cognitive attributes. The aim of this study was to investigate evidence of validity of the Psychological Development Index for the Comprehensive System Zulliger Test. Method: The data analysis considered the Mann-Whitney test, Cohen's d, Spearman's correlation and the coefficient difference test. Finally, multiple regression analysis was used to verify the relationship between age and Developmental Index with a 253 children and adolescents between 7 and 14 years of age participated. Results: The results indicated evidence of concurrent criterion validity to Development Index, pointing out statistically significant differences between age groups. Conclusion: Regarding the evidence of convergent validity of the Development Index between the Zulliger Comprehensive System and the Rorschach Performance Assessment System tests, nothing can be proven. This study is limited by the age range of the sample, as well as the transposition of the Rorschach Performance Assessment System Development Index calculation to the Zulliger Comprehensive System. Objective psychosocial emotional attributes Test Method MannWhitney Mann Whitney test Cohens Cohen s d Spearmans Spearman Finally 25 1 participated Results groups Conclusion tests proven sample 2

RESUMO Objetivo: A maturidade psicológica pode ser compreendida como um construto multifacetado que abrange diversos atributos psicossociais, emocionais e cognitivos. O objetivo deste estudo foi investigar evidências de validade do Índice de Desenvolvimento Psicológico para o Teste Zulliger do Sistema Compreensivo. Método: A análise dos dados considerou o teste de Mann-Whitney, d de Cohen, correlação de Spearman e teste de coeficiente de diferença. Por fim, utilizou-se análise de regressão múltipla para verificar a relação entre idade e Índice de Desenvolvimento, com a participação de 253 crianças e adolescentes entre 7 e 14 anos. Resultados: Os resultados indicaram evidências de validade de critério concorrente para o Índice de Desenvolvimento, apontando diferenças estatisticamente significativas entre as faixas etárias. Conclusão: Quanto às evidências de validade convergente do Índice de Desenvolvimento entre os testes do Sistema Compreensivo Zulliger e do Sistema de Avaliação de Desempenho Rorschach, nada pode ser comprovado. Este estudo limita-se à faixa etária da amostra, bem como à transposição do cálculo do Índice de Desenvolvimento do Sistema de Avaliação de Desempenho de Rorschach para o Sistema Compreensivo Zulliger. Objetivo psicossociais cognitivos Método MannWhitney, MannWhitney Mann Whitney, Whitney Mann-Whitney Cohen diferença fim utilizouse utilizou se 25 1 anos Resultados etárias Conclusão comprovado limitase limita amostra 2

ABSTRACT This study assessed the effect of strain and enriched cage stocking density on performance, egg size distribution, egg quality, and welfare status in laying hens. Lohmann brown (LB) and Lohmann LSL Classic (LW) strains at 20 weeks of age were allotted to different cage stocking densities, with 1016, 762, or 610 cm2 of cage floor area per hen. Live body weight at the age at sexual maturity and at 52 weeks of age, feather condition, and some egg quality parameters differed between hen strains and among stocking densities (p<0.01; p<0.05). However, age at sexual maturity, livability, egg production, heterophil-to-lymphocyte ratio, and duration of tonic immobility were similar between hen strains and among stocking densities (p>0.05). Furthermore, egg size distribution was similar between hen strains (p>0.05), but dissimilar among stocking densities (p<0.01). Rectal and comb temperatures differed between hen strains and among stocking densities, respectively (p<0.01; p<0.05). The age of hens influenced egg quality variables (except for egg weight and shape index), feather condition, and body region temperatures (p<0.01). These results suggest that an enriched cage floor area of up to 610 cm2 per hen does not compromise production performance and welfare status, except for the body weight of laying hens. Additionally, the two strains might be at similar levels regarding overall performance and welfare status, excluding body weight and feather condition. LB (LB LW (LW 2 1016 762 61 cm 5 condition p<0.01 p001 p 0 01 (p<0.01 p<0.05. p005 p<0.05 . 05 p<0.05) However livability heterophiltolymphocyte heterophil lymphocyte ratio p>0.05. p>0.05 (p>0.05) Furthermore p>0.05, , p<0.01. (p<0.01) index, index index) Additionally 101 76 6 p<0.0 p00 (p<0.0 p>0.0 (p>0.05 10 7 p<0. p0 (p<0. p>0. (p>0.0 1 p<0 (p<0 p>0 (p>0. p< (p< p> (p>0 (p (p>

RESUMO Objetivo: Analisar a experiência de mulheres com 35 anos ou mais acerca da transição para a maternidade não planejada. Método: Estudo qualitativo descritivo, com entrevistas semiestruturadas com seis mulheres nessa faixa etária, selecionadas por conveniência, realizado em um ambulatório de pré-natal de alto risco entre julho de 2022 e julho de 2023. A análise foi baseada na Teoria das Transições. Resultados: Identificaram-se três categorias principais: Propriedades da transição (atributos da maternidade tardia); Condições da transição (fatores pessoais, sociais e comunitários como facilitadores ou inibidores); e Padrões de resposta (estratégias de enfrentamento e adaptação). Os resultados destacam a complexidade emocional e psicossocial, incluindo impacto do estigma social, desafios de saúde e a dualidade da idade avançada, que traz desafios e maturidade. Conclusão: Enfatiza-se a necessidade de políticas públicas e suporte especializado para promover saúde mental, bem-estar e integração social, visando uma transição mais saudável e empoderada para a maternidade. Objetivo 3 planejada Método descritivo etária conveniência prénatal pré natal 202 2023 Transições Resultados Identificaramse Identificaram se principais atributos tardia tardia) fatores pessoais inibidores inibidores) estratégias adaptação. adaptação . adaptação) psicossocial social avançada maturidade Conclusão Enfatizase Enfatiza mental bemestar bem estar 20 2

RESUMEN Objetivo: Analizar la experiencia de mujeres de 35 años o más respecto de la transición a la maternidad no planificada. Método: Estudio cualitativo descriptivo, con entrevistas semiestructuradas a seis mujeres de este grupo etario, seleccionadas por conveniencia, realizado en una clínica prenatal de alto riesgo entre julio de 2022 y julio de 2023. El análisis se basó en la Teoría de las Transiciones. Resultados: Se identificaron tres categorías principales: Propiedades de la transición (atributos de la maternidad tardía); Condiciones de transición (factores personales, sociales y comunitarios como facilitadores o inhibidores); y Patrones de respuesta (estrategias de afrontamiento y adaptación). Los resultados resaltan la complejidad emocional y psicosocial, incluido el impacto del estigma social, los desafíos de salud y la dualidad de la vejez, que trae desafíos y madurez. Conclusión: Se enfatiza la necesidad de políticas públicas y apoyo especializado para promover la salud mental, el bienestar y la integración social, apuntando a una transición a la maternidad más saludable y empoderada. Objetivo 3 planificada Método descriptivo etario conveniencia 202 2023 Transiciones Resultados principales atributos tardía tardía) factores personales inhibidores inhibidores) estrategias adaptación. adaptación . adaptación) psicosocial social vejez madurez Conclusión mental empoderada 20 2

ABSTRACT Objective: To analyze the experience of women aged 35 or over regarding the transition to unplanned motherhood. Method: A descriptive qualitative study, with semi-structured interviews with six women in this age group, selected by convenience, carried out in a high-risk prenatal clinic between July 2022 and July 2023. Analysis was based on Transitions Theory. Results: Three main categories were identified: Transition properties (attributes of late motherhood); Transition conditions (personal, social and community factors as facilitators or inhibitors); and Response patterns (coping and adaptation strategies). The results highlight the emotional and psychosocial complexity, including the impact of social stigma, health challenges and the duality of old age, which brings both challenges and maturity. Conclusion: The need for public policies and specialized support to promote mental health, well-being and social integration is emphasized, aiming for a healthier and more empowered transition to motherhood. Objective 3 motherhood Method study semistructured semi structured group convenience highrisk high risk 202 2023 Theory Results identified attributes motherhood) personal, personal (personal inhibitors inhibitors) coping strategies. strategies . strategies) complexity stigma maturity Conclusion wellbeing well being emphasized 20 2

Resumo A organização da informação arquivística na era digital exige procedimentos específicos; seja pelo advento dos documentos arquivísticos digitais, seja porque houve a alteração do objeto de estudo de conjuntos de documentos para o conjunto de informações orgânicas e a arquivologia assiste a novas interlocuções teórico-metodológicas com distintas disciplinas que também possuem como objeto a informação, como a Ciência da Informação. À luz dessas evoluções, a presente pesquisa parte da problemática de analisar de que forma a gestão de documentos arquivísticos digitais pode ser mensurada em níveis no interior dos organismos produtores de documentos. Para esse fim, o presente artigo apresenta um modelo de aferição de maturidade em gestão de documentos arquivísticos produzidos e mantidos em meio digital. Objetivo: propor um modelo de aferição do nível de maturidade em gestão de documentos a partir do estudo de modelos existentes. Metodologia: pesquisa qualitativa, documental e bibliográfica. Resultados: ao aplicar o novo modelo de aferição do nível de maturidade em gestão de documentos, torna-se possível entender que a proposta é válida para aferir o nível de maturidade em gestão de documentos nas instituições produtoras. Conclusões: esta pesquisa demonstrou que o modelo de aferição de maturidade em gestão de documentos é válido e pode ser aplicado em qualquer instituição pública na era da informação digital para atestar a qualidade da gestão de documentos arquivísticos do ente custodia dor. específicos teóricometodológicas teórico metodológicas Informação evoluções fim Objetivo existentes Metodologia qualitativa bibliográfica Resultados tornase torna se produtoras Conclusões dor

Abstract The organization of archival information in the digital age requires specific procedures; either because of the advent of digital archival records, or because the object of study has changed from sets of records to sets of organic information and archivology is witnessing new theoretical-methodological interlocutions with different disciplines that also have information as their object, such as Information Science. In the light of these developments, this research is based on the problem of analyzing how the management of digital archival documents can be measured at levels within document-producing organizations. To this end, this article presents a model for measuring maturity in the management of archival documents produced and kept in digital format. Objective: to propose a model for measuring the level of maturity in document management based on a study of existing models. Methodology: qualitative, documentary and bibliographical research. Results: by applying the new model for measuring the level of maturity in document management, it is possible to understand that the proposal is valid for measuring the level of maturity in document management in producing institutions. Conclusions: This research has shown that the record management maturity measurement model is valid and can be applied to any public institution in the digital information age to certify the quality of the custodian’s archival record management. procedures theoreticalmethodological theoretical methodological Science developments documentproducing organizations end format Objective models Methodology qualitative Results institutions Conclusions custodians custodian s