This work developed an effective and eco-friendly analytical method to support quality control for Brazilian Bill proposal No. 5332/2009. The bill advocates the creation of the “Brazilian bread” by mandating the incorporation of cassava byproducts into wheat flour, with the aim of reducing Brazil’s external dependency on wheat imports and promoting domestic cassava family farming. For this, a handheld near-infrared (NIR) spectrophotometer was utilized for on-site determination of cassava starch in commercial wheat flour. The quantitative analysis, which utilized NIR spectra pre-processed with offset correction (OFF) combined with linear baseline correction (LBC), alongside the successive projections algorithm for interval selection in partial least squares (iSPA-PLS), exhibited superior predictive capability, achieving a relative error of prediction below 8%. Furthermore, the classification process, which involved NIR spectra pre-processed with LBC and iSPA-PLS for discriminant analysis (iSPA-PLS-DA), yielded an impressive 94% overall accuracy, with only 3 misclassifications in the test set. ecofriendly eco friendly No 53322009 5332 2009 5332/2009 bread flour Brazils Brazil s farming this nearinfrared near infrared (NIR onsite site preprocessed pre processed OFF (OFF LBC, , (LBC) iSPAPLS, iSPAPLS iSPA PLS (iSPA-PLS) capability 8 8% Furthermore process iSPAPLSDA, iSPAPLSDA DA (iSPA-PLS-DA) 94 accuracy set 5332200 533 200 5332/200 (LBC (iSPA-PLS (iSPA-PLS-DA 9 533220 53 20 5332/20 53322 5 2 5332/2 5332/

This study aims to propose a new method for derivatizing fatty acids (FAs) from human milk (HM), eliminating the lipid extraction step, and simplifying the preparation for gas chromatography with a flame ionization detection (GC-FID) analysis to quantify the FAs. The Design Expert software optimized the reaction times, concentrations, and sample amount. The proposed method (PM) was validated for lyophilized HM and results for the figures of merit for precision in relative standard deviation (RSD) (RSDintra-day 1.34-4.03% and RSDinter day 2.08 5.16%), accuracy (99.87-102.16%), and robustness are within a linear range of 3 to 38% lipids in HM samples. The atmospheric solids analysis probe tandem mass spectrometry (ASAP-MS/MS) technique confirmed the efficiency of PM by expressing the molecular composition of triacylglycerol formed by FAs from the GC-FID technique. The PM requires a small sample size and conducts derivatization directly in the sample matrix, minimizing extraction errors. (FAs HM, , (HM) step GCFID GC FID (GC-FID times concentrations amount (PM RSD (RSD RSDintraday RSDintra 1.344.03% 134403 1.34 4.03% 1 34 4 03 1.34-4.03 208 2 08 2.0 5.16%, 516 5.16% 5 16 5.16%) 99.87102.16%, 998710216 99.87 102.16% 99 87 102 (99.87-102.16%) 38 samples ASAPMS/MS ASAPMSMS ASAP MS/MS MS (ASAP-MS/MS matrix errors (HM 344 1.344.03 13440 134 1.3 403 4.03 0 1.34-4.0 20 2. 51 5.16 87102 99.87102.16% 99871021 9987 99.8 10216 102.16 9 8 10 (99.87-102.16% ASAPMS MSMS 1.344.0 1344 13 1. 40 4.0 1.34-4. 5.1 8710 99.87102.16 9987102 998 99. 1021 102.1 (99.87-102.16 1.344. 4. 1.34-4 5. 871 99.87102.1 998710 102. (99.87-102.1 1.344 1.34- 99.87102. 99871 (99.87-102. 99.87102 (99.87-102 99.8710 (99.87-10 99.871 (99.87-1 (99.87- (99.87 (99.8 (99. (99 (9 (

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by extracellular accumulation of amyloid-β (Aβ) peptides in the brain. This study demonstrates the direct association of the disposable pipette extraction (DPX) with tandem mass spectrometry (MS/MS) for the analysis of Aβ peptides in cerebrospinal fluid (CSF) samples. Different parameters were optimized in order to improve detectability in the MS/MS including mobile phase percentage of ammonium hydroxide, mobile phase flow rate and acquisition mode. Also, this method used an electrospray ionization (ESI) low-flow probe and direct infusion of an organic solution in the MS/MS. The DPX-MS/MS method showed adequate linearity for determining Aβ peptides in CSF-linearity ranged from 0.1 to 1.5 ng mL 1. The coefficients of determination were higher than 0.99; the precision coefficient of variation (CV) ranged from 0.3 to 12.7%; and the accuracy relative standard deviation (RSD) ranged from -13.6 to 13.2%. Alzheimers Alzheimer s AD (AD amyloidβ amyloid β (Aβ brain DPX (DPX MSMS MS (MS/MS CSF (CSF samples hydroxide mode Also ESI (ESI lowflow low DPXMS/MS DPXMSMS CSFlinearity 01 0 1 0. 15 5 0.99 099 99 CV (CV 03 3 12.7% 127 12 7 RSD (RSD 13.6 136 13 6 -13. 132 2 13.2% DPXMS 0.9 09 9 12.7 13. -13 13.2 12. -1 -

ABSTRACT Purpose: To compare the refractive prediction error of Hill-radial basis function 3.0 with those of 3 conventional formulas and 11 combination methods in eyes with short axial lengths. Methods: The refractive prediction error was calculated using 4 formulas (Hoffer Q, SRK-T, Haigis, and Hill-RBF) and 11 combination methods (average of two or more methods). The absolute error was determined, and the proportion of eyes within 0.25-diopter (D) increments of absolute error was analyzed. Furthermore, the intraclass correlation coefficients of each method were computed to evaluate the agreement between target refractive error and postoperative spherical equivalent. Results: This study included 87 eyes. Based on the refractive prediction error findings, Hoffer Q formula exhibited the highest myopic errors, followed by SRK-T, Hill-RBF, and Haigis. Among all the methods, the Haigis and Hill-RBF combination yielded a mean refractive prediction error closest to zero. The SRK-T and Hill-RBF combination showed the lowest mean absolute error, whereas the Hoffer Q, SRK-T, and Haigis combination had the lowest median absolute error. Hill-radial basis function exhibited the highest intraclass correlation coefficient, whereas SRK-T showed the lowest. Haigis and Hill-RBF, as well as the combination of both, demonstrated the lowest proportion of refractive surprises (absolute error >1.00 D). Among the individual formulas, Hill-RBF had the highest success rate (absolute error ≤0.50 D). Moreover, among all the methods, the SRK-T and Hill-RBF combination exhibited the highest success rate. Conclusions: Hill-radial basis function showed accuracy comparable to or surpassing that of conventional formulas in eyes with short axial lengths. The use and integration of various formulas in cataract surgery for eyes with short axial lengths may help reduce the incidence of refractive surprises. Purpose Hillradial Hill radial 30 0 3. 1 Methods SRKT, SRKT SRK T, T HillRBF RBF average methods. . methods) determined 0.25diopter 025diopter diopter 0.25 25 D (D analyzed Furthermore equivalent Results 8 findings errors HillRBF, RBF, zero coefficient both 100 00 >1.0 D. D) 050 50 ≤0.5 Moreover Conclusions 25diopter 025 0.2 2 10 >1. 05 5 ≤0. 02 0. >1 ≤0 > ≤

Over the last two decades, metabolomics has emerged as a pivotal tool in multidisciplinary research, providing invaluable insights into metabolome modulations and finding applications across various scientific domains, including medicine and agronomy. Nonetheless, the absence of standardized procedures in sample preparation, data acquisition, and documentation of data quality presents a significant challenge. This review underscores the critical importance of quality assurance and quality control (QA/QC) in untargeted metabolomics, advocating for the establishment of agreed-upon QA/QC reporting standards within the scientific community. We discuss the requisite quality controls at various stages of untargeted metabolomics studies, encompassing blank samples, pooled samples, and the utilization of external quality control samples. Methods for assessing accuracy, reproducibility, and identifying/correcting batch effects are addressed. Furthermore, emphasis is placed on standardizing the description of QA/QC data in scientific publications and repositories to foster reproducibility and transparency. We recommend the publication of QC data alongside studies in appropriate databases to facilitate data comparison and sharing among researchers, thereby enhancing the quality of untargeted metabolomics research. In summary, implementing standardized QA/QC data reporting, along with promoting best practices within the untargeted metabolomics community, is crucial for improving result quality and credibility and advancing research utilizing this powerful technique. decades domains agronomy Nonetheless preparation acquisition challenge QAQC QA (QA/QC agreedupon agreed upon community samples accuracy identifyingcorrecting identifying correcting addressed Furthermore transparency researchers summary technique

This research aims to develop a precise and efficient dispersive solid-phase microextraction (DSPE) technique using third-generation polyamidoamine (PAMAM) dendrimer-grafted nanoparticles to quantify benzoylurea pesticides in green tea, black tea, and oolong tea infusions. The extraction efficiency is optimized through single-factor adjustments of key parameters, including adsorbent quantity (5-20 mg), adsorption duration (5-20 min), desorbent identity (methanol, acetonitrile), volume (100-600 μL), sodium chloride concentration (0-10%, m/v), and sample solution pH (3-8). The optimized method demonstrates linearity in the range of 2-500 μg L-1, with limits of detection (LODs) ranging from 0.6-1.5 μg L-1 and limits of quantification (LOQs) from 2.0 5.0 μg L-1. Recovery rates of 81.2-96.0% are achieved, with intra-day relative standard deviations (RSDs) of 1.4-2.8% and inter-day relative standard deviations of 2.0-3.9%, indicating high accuracy and repeatability. The successful application of detecting residues in commercial tea samples underscores the strong potential of the technique to determine benzoylurea analyte levels. solidphase solid phase DSPE (DSPE thirdgeneration third generation PAMAM (PAMAM dendrimergrafted dendrimer grafted infusions singlefactor single factor parameters 520 5 20 (5-2 mg, mg , mg) min, min min) methanol, methanol (methanol acetonitrile, acetonitrile acetonitrile) 100600 100 600 (100-60 μL, μL μL) 010%, 010 0 10%, 10 (0-10% m/v, mv m/v m v m/v) 38. 38 3 8 . (3-8) 2500 2 500 2-50 L1, L1 L 1, 1 LODs (LODs 0.61.5 0615 0.6 1.5 6 0.6-1. L- LOQs (LOQs 2. 50 5. L1. 1. 81.296.0% 812960 81.2 96.0% 81 96 81.2-96.0 achieved intraday intra day RSDs (RSDs 1.42.8% 1428 1.4 2.8% 4 1.4-2.8 interday inter 2.03.9%, 2039 3.9%, 9 2.0-3.9% repeatability levels 52 (5- 10060 60 (100-6 010% 01 10% (0-10 (3-8 250 2-5 61 0.61. 061 06 0. 15 0.6-1 296 81.296.0 81296 812 81. 960 96.0 81.2-96. 42 1.42.8 142 14 28 2.8 1.4-2. 03 2.03.9% 203 39 3.9% 2.0-3.9 (5 1006 (100- (0-1 (3- 25 2- 0.61 0.6- 29 81.296. 8129 96. 81.2-96 1.42. 1.4-2 2.03.9 3.9 2.0-3. ( (100 (0- (3 81.296 81.2-9 1.42 1.4- 2.03. 3. 2.0-3 (10 (0 81.29 81.2- 2.03 2.0- (1

The inhibition of the fatty acid amide hydrolase (FAAH), an endocannabinoid system component, emerged as a potentially new therapeutic target for a range of clinical disorders such as acute and chronic pain. Some α-ketoheterocycle derivatives demonstrated interesting analgesic and anti-inflammatory activities in vitro. Ligand-Based Drug Design techniques such as knowledge graph convolutional networks (kGCN) and hologram quantitative structure-activity relationship (HQSAR) using α-ketoheterocycle derivatives from five different datasets were generated to discover the relation between the chemical structures and the inhibition activity. Meanwhile, structure-based drug design simulations as interaction fields (MIF), molecular docking, and ligand sites studies (LSI) from FAAH were performed using Autogrid software and FTmap/FTsite servers. The results of both studies were merged to propose predictive models. The resulting kGCN model demonstrated adequate accuracy area under the curve by receiver operating characteristic (AUC-ROC 0.7922). From contribution maps of the Ligand-Based Drug Design (LBDD) models and the generated probes using MIF and LSI, it was observed that the oxazole ring, the ketone group, and the apolar chain present in the structures of the inhibitors are important, besides the evidence of the Cys269 and Val270 residues importance for the potential interaction, confirmed by carried docking studies. These fragments and structural information can be used to carry out new FAAH potential inhibitors studies and report kGCN as an accurate classification technique. FAAH, , (FAAH) component pain αketoheterocycle α ketoheterocycle antiinflammatory anti inflammatory vitro LigandBased Ligand Based (kGCN structureactivity structure activity HQSAR (HQSAR Meanwhile structurebased based MIF, (MIF) LSI (LSI FTmapFTsite FTmap FTsite servers AUCROC AUC ROC 0.7922. 07922 0.7922 . 0 7922 0.7922) LBDD (LBDD ring group important Cys Cys26 Val Val27 technique (FAAH (MIF 0792 0.792 792 Cys2 Val2 079 0.79 79 07 0.7 7 0.

Nanocomposites of GO/γ-Fe2O3 were used for magnetic dispersive solid-phase microextraction (m-d-μ-SPE) of six pesticides from river water samples, followed by the determination using high performance liquid chromatography-diode array detection. The synthesis of the nanocomposites is described and characterized using Fourier transform-infrared spectroscopy, X-ray diffraction, and scanning electron microscopy. A central composite design was used to optimize the extraction time, sample solution pH, and adsorbent amount. The solvent type and volume for desorption and the effect of the ionic strength for adsorption were also investigated. The optimum adsorption conditions were achieved at 84 min of extraction time, pH 5.4, 115 mg of absorbent, and 1% (m/v) of NaCl, while the desorption solvent selected was 1.0 mL of methanol-acetic acid (9:1, v/v). The limits of detection ranged from 0.1 to 0.9 μg L-1, and a good precision was achieved with relative standard deviation (RSD) lower than 7.6% (n = 10). The accuracy of the method was accessed by recovery tests ranging from 82 to 117% (n = 3, RSD < 8%). GO/γFe2O3 GOγFe2O3 GOγFeO GO/γ Fe2O3 GO γ Fe O GO/γ-Fe2O solidphase solid phase mdμSPE m d μ SPE (m-d-μ-SPE samples chromatographydiode chromatography diode transforminfrared transform infrared spectroscopy Xray X ray diffraction microscopy time amount investigated 8 54 5 4 5.4 11 absorbent 1 m/v mv v (m/v NaCl 10 0 1. methanolacetic methanol acetic 91, 91 9 1, (9:1 v/v. vv v/v . v/v) 01 0. 09 L1, L1 L L-1 (RSD 76 7 6 7.6 n 10. 10) 117 3 8%. 8% 8%) γFe2O3 γFe GO/γFe2O GOγFe GOγFe2O GOγ FeO Fe2O 5. (9: L- 7. γFeO γFe2O (9 (

RESUMO As pimenteiras ornamentais apresentam variabilidade genética que pode ser acessada por meio de caracteres morfológicos e moleculares. A seleção de genótipos para formação de população base para o melhoramento pode ser realizada por meio de análise conjunta de vários tipos de dados, proporcionando maior precisão na seleção. Nessa perspectiva, este estudo teve como objetivo avaliar a diversidade entre acessos de pimenta com base na análise de características fenotípicas e marcadores moleculares e selecionar os melhores para serem utilizados como parentais em programas de melhoramento. O trabalho foi realizado no Centro de Ciências Agrárias da Universidade Federal da Paraíba, Paraíba, Brasil. Foram utilizados 16 genótipos de pimenteiras ornamentais, e caracterizados quanto a oito caracteres quantitativos, nove qualitativos e 18 pares de iniciadores microssatélites. As análises simultâneas das variáveis foram realizadas usando o método de agrupamento de Tocher, agrupamento do algoritmo de Ward e a matriz de dissimilaridades. Os métodos de agrupamentos foram eficientes na separação dos genótipos, identificando variabilidade genética e precisão na seleção por meio da análise conjunta de dados quantitativos, qualitativos e moleculares. Diferentes grupos foram formados entre os genótipos pelo método de Tocher (seis grupos) e pelo método de Ward (três grupos). Existe variabilidade genética entre os genótipos de pimenteiras ornamentais, considerando análise conjunta de dados quantitativos, qualitativos e moleculares. Características qualitativas são importantes na identificação de divergência genética entre acessos de pimenteira ornamental. Os genótipos UFPB 46, 134, 137, 443 e 449, o mini pimentão Akamu e a cultivar Calypso são indicados para seleção, podem ser utilizados para realizar cruzamentos e dar continuidade ao programa de melhoramento genético. perspectiva Paraíba Brasil 1 quantitativos microssatélites dissimilaridades seis três grupos. . ornamental 46 134 137 44 449 genético 4 13

ABSTRACT Ornamental pepper plants have genetic variability, which can be accessed through morphological and molecular traits. Genotype selection to form the base population for breeding can be performed through the joint analysis of several types of data, providing greater selection accuracy. From this perspective, this study aimed to evaluate the diversity among pepper accessions based on analysis of phenotypic traits and molecular markers and to select the best ones to use as parents in breeding programs. The study was carried out at the Centro de Ciências Agrárias of the Universidade Federal da Paraíba, Paraíba, Brazil. Sixteen ornamental pepper genotypes were used and characterized for eight quantitative traits, nine qualitative traits, and 18 pairs of microsatellite primers. Simultaneous variable analyses were performed using Tocher’s clustering method, Ward’s clustering algorithm, and the dissimilarity matrix. The clustering methods were efficient in separating the genotypes, identifying genetic variability, and accuracy in the selection through the joint analysis of quantitative, qualitative, and molecular data. Different groups were formed among the genotypes by Tocher’s method (six groups) and Ward’s method (three groups). There is genetic variability among ornamental pepper genotypes considering the joint analysis of quantitative, qualitative, and molecular data. Qualitative traits are important in the identification of genetic divergence among ornamental pepper accessions. The UFPB genotypes 46, 134, 137, 443 and 449, the mini pepper Akamu, and the cultivar Calypso are indicated for selection and can be used to carry out crosses and continue the breeding program. data perspective programs Paraíba Brazil 1 primers Tochers Tocher s Wards Ward algorithm matrix six three groups. . 46 134 137 44 449 Akamu program 4 13

RESUMO A solução fundamental para o problema do entupimento do emissor é explorar o projeto ideal da estrutura do emissor e melhorar sua capacidade anti-entupimento. O objetivo da pesquisa foi selecionar a forma estrutural ideal do caminho de fluxo do emissor em sistemas de irrigação por gotejamento utilizando fontes de água de qualidade inferior, proporcionando suporte teórico para melhorar a capacidade anti-obstrução do próprio emissor e para o projeto de novos produtos de emissores. A seleção da estrutura do caminho do fluxo do emissor não tem sido conduzida com base na determinação do modelo de simulação apropriado com a condição complexa de qualidade da água. Para tanto, determinou-se o modelo de movimento interno do fluido adequado do emissor, e avaliou-se de forma abrangente o desempenho hidráulico e o desempenho anti-entupimento das cinco estruturas representativas da trajetória de fluxo no país e no exterior, e finalmente determinou-se a estrutura ótima da trajetória de fluxo do emissor. Os resultados da pesquisa indicaram que o modelo RNG k-ε foi o mais adequado para simular a área do fluxo no emissor por meio da análise abrangente da lacuna entre os valores simulados e os valores medidos, da precisão do cálculo e da eficiência computacional. A trajetória de fluxo fractal foi relativamente ótima para o desempenho hidráulico e para o desempenho anti-entupimento. Este estudo pode fornecer suporte teórico para melhorar a própria habilidade anti-obstrução do emissor e o projeto de novo produto de emissor. antientupimento. antientupimento anti entupimento. inferior antiobstrução obstrução emissores tanto determinouse determinou se avaliouse avaliou exterior kε k ε medidos computacional

ABSTRACT The fundamental solution to the problem of emitter clogging is to explore the optimal structure design of emitter and improve its anti-clogging ability. The research objective was to select the optimal structural form of the emitter flow path in drip irrigation systems using inferior water sources, which can provide theoretical support for improving the anti-clogging ability of the emitter itself and designing new emitter products. The selection of the flow path structure of the emitter has not been conducted on the basis of determining the appropriate simulation model with the condition of complex water quality. Therefore, the appropriate internal fluid movement model of the emitter was determined, the hydraulic performance and anti-clogging performance of the five nationally and internationally representative flow path structures were comprehensively evaluated, and finally the optimal structure of the emitter flow path was determined. The research results indicated that RNG k - ε model was the most suitable to simulate the flow field in the emitter by comprehensive analysis of the gap between simulated values and the measured values, the calculation accuracy and computational efficiency. The fractal flow path was relatively optimal for hydraulic performance and for anti-clogging performance. This study can provide theoretical support for improving the anti-clogging ability of the emitter itself and the design of the new emitter product. anticlogging anti sources products quality Therefore determined evaluated efficiency product

ABSTRACT Adequate seed placement is essential for consistent crop emergence and initial growth. Pneumatic seed metering systems offer superior longitudinal seed distribution accuracy compared to traditional methods, yet certain factors can influence this precision. For instance, seed physical properties may be altered by phytosanitary treatments applied either on-farm or industrially. This study examined the effects of phytosanitary treatment type and graphite addition on soybean seed deposition using an electric-driven pneumatic feeder under simulated sowing conditions. Seed distribution was monitored with an optical sensor. Four treatment groups were established: untreated without graphite, untreated with graphite added, on-farm treated with graphite, and industrially treated with graphite. Parameters assessed included average spacing between seeds, coefficient of variation, precision index, multiple and failed spacings, and percentage of acceptable spacing. Results indicate that prior seed treatment does not significantly affect overall planting accuracy. However, seed spacing varied between the untreated and on-farm treated groups, with the latter demonstrating closer proximity to optimal values. Both on-farm and industrial treatments yielded more uniform seed deposition, as indicated by a lower coefficient of variation. Regardless of seed treatment, the pneumatic feeder consistently performed effectively. growth methods instance onfarm farm electricdriven electric driven conditions sensor established added seeds variation index spacings However values effectively

RESUMO A deposição adequada de sementes tem grande importância na uniformidade da emergência e no desenvolvimento inicial das culturas. Uma maior precisão na distribuição longitudinal de sementes é possível com mecanismos dosadores de sementes pneumáticos em relação aos convencionais, mas existem alguns aspectos que afetam essa precisão. Por exemplo, a qualidade física das sementes pode ser impactada pelo seu tratamento fitossanitário, que pode ser feito na propriedade ou na indústria. Nesse contexto, este estudo investigou o impacto do tipo de tratamento fitossanitário e do uso de grafite na deposição de sementes de soja por meio de dosador pneumático com acionamento elétrico em bancada estática, simulando a semeadura e monitorando a distribuição das sementes com sensor óptico. As sementes foram submetidas a quatro tratamentos distintos: sem grafite, sem tratamento com adição de grafite, tratamento on-farm com adição de grafite e tratamento industrial com adição de grafite. Foram estudados o espaçamento médio entre deposições, coeficiente de variação de semeadura, índice de precisão, espaçamentos múltiplos e falhas e percentual de espaçamento aceitável. Os resultados indicam que o espaçamento adequado no plantio não é significativamente impactado pelo método de tratamento prévio das sementes. O espaçamento entre sementes diferiu entre os tratamentos sem grafite e pelo tratamento on-farm, sendo este último mais próximo do ótimo e o tratamento sem grafite mais distante do espaçamento ideal. Um coeficiente de variação de semeadura mais baixo indica que a deposição uniforme foi alcançada com os procedimentos on-farm e industriais. Independentemente do tratamento de sementes, o dosador pneumático demonstrou eficácia. culturas convencionais exemplo indústria contexto estática óptico distintos onfarm on farm deposições aceitável onfarm, farm, ideal industriais eficácia

ABSTRACT: The study of adaptability, stability, and productivity is essential for selecting and recommending superior genotypes. This fact is particularly the case for the introduction of common bean cultivars in Rio de Janeiro, Brazil, whose production is negligible and does not meet the internal demand. Thus, this study estimated genetic parameters and selection gains and undertake a simultaneous selection for adaptability, stability, and productivity in black bean genotypes via mixed models. The investigation was carried out in three municipalities in the state of Rio de Janeiro during three crop years. The trials were set up in a randomized block design with 11 genotypes and three replications. High mean heritability (81%) and selection accuracy (90%), as well as good selection prospects, were observed. Gains between 1.03 and 9.49% were achieved for grain yield. Simultaneous selection was efficient, indicating two black bean lines (CNFP 15290 and CNFP 15361) as the most productive, adaptable, and stable. As such, these lines have the potential to be released as new black bean cultivars for the state of Rio de Janeiro. ABSTRACT adaptability stability Brazil demand Thus models years 1 replications 81% 81 (81% 90%, 90 90% , (90%) prospects observed 103 03 1.0 949 9 49 9.49 yield efficient 1529 15361 productive adaptable stable such 8 (81 (90% 10 0 1. 94 4 9.4 152 1536 (8 (90 9. 15 153 ( (9

RESUMO: O estudo de adaptabilidade, estabilidade e produtividade é importante para selecionar e recomendar genótipos superiores. Esse fato é particularmente válido para a introdução de cultivares de feijão comum no Rio de Janeiro, Brasil, cuja produção é ínfima e não atende a demanda interna. Assim, este trabalho teve como objetivo estimar parâmetros genéticos e ganhos de seleção e realizar uma seleção simultânea para adaptabilidade, estabilidade e produtividade de genótipos de feijão preto através de modelos mistos. O estudo foi realizado em três municípios do estado do Rio de Janeiro e em três anos agrícolas. Os ensaios foram instalados em delineamento de blocos casualizados com 11 genótipos e três repetições. Observou-se alta herdabilidade média (81%), acurácia seletiva (90%) e boas perspectivas de seleção. Também foram observados ganhos satisfatórios para a característica entre 1,03 e 9,49%. A seleção simultânea foi eficiente e permitiu selecionar duas linhagens de feijão preto CNFP (15290 e 15361) como sendo as mais produtivas, adaptáveis e estáveis e, portanto, têm potencial para serem lançadas como novas cultivares de feijão preto para o estado do Rio de Janeiro. RESUMO adaptabilidade superiores Brasil interna Assim mistos agrícolas 1 repetições Observouse Observou se 81%, 81 81% , (81%) 90% 90 (90% 103 03 1,0 949 9 49 9,49% 15290 (1529 15361 produtivas portanto 8 (81% (90 10 0 1, 94 4 9,49 1529 (152 1536 (81 (9 9,4 152 (15 153 (8 ( 9, 15 (1

Resumen Objetivo: desarrollar un método para la cobertura delta de portafolios de opciones europeas listadas con base en la teoría del cálculo conformable que mejora la precisión de las predicciones usando la aproximación de primer orden. Metodología: permitimos que la primera derivada en el modelo clásico de Black-Scholes-Merton tenga un orden fraccional 0 ≤ α ≤ 1 y calculamos la delta correspondiente de un portafolio como función de este parámetro conformable. Resultados: aplicando este método a un portafolio conformado de ocho opciones europeas listadas sobre el índice SPX, encontramos que la cobertura conformable genera predicciones más precisas, en promedio, que la cobertura tradicional. Limitaciones: este método es aplicable solamente a la cobertura delta (hedging) de opciones europeas. Originalidad: esta es la primera aplicación exitosa del cálculo conformable a la cobertura delta en opciones europeas. Conclusiones: la aplicación del cálculo conformable permite mayor flexibilidad en la aproximación local implícita en la cobertura delta de portafolios de acciones europeas y se ofrece como una metodología novel y de mayor precisión que la tradicional.

Abstract Objective: we aim to develop a method for delta hedging portfolios of European options based on the theory of conformable calculus which improves accuracy of risk management of listed options in a first-order approximation. Methodology: we allow the time derivative in the classic Black-Scholes-Merton model to have a fractional order 0 ≤ α ≤ 1 and calculate the corresponding delta of a portfolio of listed options as a function of this conformable parameter. Results: applying this method to a portfolio consisting of eight European options on the SPX index, we find that conformable delta hedging offers more accurate average predictions than classical delta hedging. Limitations: this method is applicable for delta hedging in European options only. Originality: this is the first successful application of conformable calculus to delta hedging in European options. Conclusions: application of Conformable Calculus allows for a greater flexibility in the local approximation to price in delta-hedging European options and offers a new and more precise methodology to this objective.

Abstract The growing use of contemporary models for predicting carbonation fronts, such as artificial neural networks, requires greater rigor in terms of database completeness. Treating carbonation depth databases as time series is a favorable alternative for quality assurance. Therefore, the aim of this article is to identify the best technique for imputing missing data in time series of carbonation depths of concrete with different compositions. The database used was information collected from concretes subjected to natural carbonation over 20 years of exposure belonging to the GEDur/UFG. Ten imputation techniques were tried, such as foward fill, moving average, interpolation and Kalman filter. All the techniques and analyses were implemented using the Python programming language in an integrated development environment. Based on the performance metrics and visual analysis, it was found that monotonic cubic spline interpolation captured the pattern of the carbonation depth curve as a function of time with greater precision and accuracy, achieving a performance index of 0.998 and RMSE between 0.106 mm and 0.863 mm depending on the concrete sample. fronts networks completeness assurance Therefore compositions 2 GEDurUFG GEDur UFG GEDur/UFG tried fill average filter environment analysis accuracy 0998 0 998 0.99 0106 106 0.10 0863 863 0.86 sample 099 99 0.9 010 10 0.1 086 86 0.8 09 9 0. 01 1 08 8

Resumo O crescente uso de modelos contemporâneos de previsão de frentes de carbonatação, como redes neurais artificiais, exige maior rigor sobre a completude dos bancos de dados. Tratar os bancos de dados de profundidades de carbonatação como séries temporais é uma alternativa favorável à garantia da qualidade. Dessa forma, este artigo tem o objetivo de identificar a melhor técnica de imputação de dados ausentes em séries temporais de profundidades de carbonatação de concretos com diferentes composições. Como banco de dados foram utilizadas as informações coletadas de concretos submetidos à carbonatação natural ao longo de 20 anos de exposição pertencentes ao grupo GEDur/UFG. Foram experimentadas dez técnicas de imputação entre as quais destacam-se, foward fill, média móvel, interpolação e filtro de Kalman. Todas as técnicas e análises foram implementadas utilizando linguagem de programação em python dentro de um ambiente de desenvolvimento integrado. Com base nas métricas de desempenho e análise visual, constatou-se que a interpolação spline monotônica cúbica capturou o padrão da curva de profundidade de carbonatação em função do tempo com maior precisão e acurácia, alcançando índice de desempenho de 0,998 e RMSE entre 0,106mm e 0,863mm dependendo da amostra de concreto. artificiais qualidade forma composições 2 GEDurUFG GEDur UFG GEDur/UFG destacamse, destacamse destacam se, se destacam-se fill móvel Kalman integrado visual constatouse constatou acurácia 0998 0 998 0,99 0106mm mm 106mm 0863mm 863mm concreto 099 99 0,9 09 9 0,

Abstract This paper aimed to analyze the effectiveness of the CCWorldWeatherGen tool, focusing on climate change in São Paulo, São Paulo State, Brazil. For this, dry-bulb temperature, relative humidity, global solar radiation, and wind speed data from the test reference year weather file (1954) and the CCWorldWeatherGen file for the 2020 period (representing the 2011-2040 period) were compared with observational data collected between 2011 and 2023 by the Meteorological Station of the Institute of Astronomy, Geophysics, and Atmospheric Sciences of the University of São Paulo. The accuracy of variables predicted using weather files was evaluated using five statistical measures of error. Annual relative root mean square error (RRMSE) values for dry-bulb temperature, relative humidity, global solar radiation, and wind speed in the morphed weather file were 17.04% (good), 17.95% (good), 31.57% (poor), and 224.44% (poor), respectively. It is concluded that CCWorldWeatherGen is suitable for generating future weather files with complete information, mainly for its practicality. However, this approach requires caution, as sequences depend on the consistency of the weather file used as a basis. tool State Brazil drybulb dry bulb temperature humidity radiation 1954 (1954 202 representing 20112040 2040 2011-204 201 Astronomy Geophysics RRMSE (RRMSE 1704 17 04 17.04 good, good , (good) 1795 95 17.95 3157 31 57 31.57 poor, poor (poor) 22444 224 44 224.44 respectively information practicality However caution basis 195 (195 20 2011204 204 2011-20 170 1 0 17.0 (good 179 9 17.9 315 3 5 31.5 (poor 2244 22 4 224.4 19 (19 2 201120 2011-2 17. 31. 224. (1 20112 2011- (

Resumo O objetivo deste artigo foi analisar a eficácia da ferramenta CCWorldWeatherGen, considerando as mudanças climáticas na cidade de São Paulo. Para tanto, as variáveis temperatura do ar (bulbo seco), umidade relativa do ar, radiação solar global, e velocidade do vento do arquivo climático de referência, de 1954, e do arquivo climático gerado pelo CCWorldWeatherGen para 2020 (representa 2011 a 2040), foram comparadas com observações da Estação Meteorológica do Instituto de Astronomia, Geofísica e Ciências Atmosféricas da Universidade de São Paulo, obtidas entre 2011 e 2023. A acurácia das variáveis dos arquivos climáticos foi avaliada por meio de cinco indicadores de erro. Os resultados da raiz do erro quadrático médio relativo (RRMSE) anual para a temperatura de bulbo seco do ar, umidade relativa do ar, radiação solar horizontal global, e velocidade do vento foram 17,04% (bom), 17,95% (bom), 31,57% (ruim) e 224,44% (ruim), respectivamente. A ferramenta CCWorldWeatherGen é adequada, especialmente por sua praticidade, para gerar futuros arquivos climáticos com informações completas. Mas seu uso demanda cautela porque as progressões dependem da consistência dos dados do arquivo climático utilizado como base. Paulo tanto seco, , seco) global referência 1954 202 representa 201 2040, 2040 2040) Astronomia 2023 RRMSE (RRMSE 1704 17 04 17,04 bom, bom (bom) 1795 95 17,95 3157 31 57 31,57 ruim (ruim 22444 224 44 224,44 ruim, respectivamente adequada praticidade completas base 195 20 204 170 1 0 17,0 (bom 179 9 17,9 315 3 5 31,5 2244 22 4 224,4 19 2 17, 31, 224,