Abstract Background Despite previous studies indicating a moderate/high incidence of angiography headache (AH), there is still limited data about the risk factors associated with its occurrence. Objective The present study aimed to assess the associations among demographic, clinical, and technical characteristics of cerebral digital subtraction angiography (DSA) and the occurrence of AH. Methods Cross-sectional analytical observational study with a sample comprised of individuals with a recommendation for elective DSA. Clinical interviews were conducted to assess the occurrence of AH, using a standardized questionnaire. Results Among 114 subjects, the mean age was 52.8 (±13.8) years old, 75.4% (86/114) were women, 29.8% (34/114) had a history of migraines, and 10.5% (12/114) had chronic headaches. The overall frequency of AH was 45.6% (52/114). Of those, 88.4% (46/52) underwent 3D angiography, 7.7% (4/52) underwent aortography, and 1.9% (1/52) underwent both procedures. There was a statistically significant association between AH and previous history of migraine (odds ratio [OR]: 4.9; 95% confidence interval [CI] 1.62–14.7; p = 0.005) and 3D angiography (OR 6.62; 95%CI: 2.04–21.5; p = 0.002). Conclusions 3D angiography is strongly associated with the occurrence of AH, which has never been reported before. The association between a previous history of migraine and AH confirms the results of previous studies. moderatehigh moderate high , (AH) demographic clinical DSA (DSA Crosssectional Cross sectional questionnaire 11 subjects 528 52 8 52. ±13.8 138 13 (±13.8 old 754 75 4 75.4 86/114 86114 86 (86/114 women 298 29 29.8 34/114 34114 34 (34/114 migraines 105 10 5 10.5 12/114 12114 12 (12/114 headaches 456 45 6 45.6 52/114. 52114 52/114 . (52/114) those 884 88 88.4 46/52 4652 46 (46/52 D 77 7 7.7 4/52 452 (4/52 aortography 19 1 9 1.9 1/52 152 (1/52 procedures odds OR [OR] 4.9 49 95 CI [CI 1.62–14.7 162147 62 14 0.005 0005 0 005 6.62 662 95%CI 95CI 2.04–21.5 204215 2 04 21 0.002. 0002 0.002 002 0.002) before (AH ±13. (±13. 75. 86/11 8611 (86/11 29. 34/11 3411 3 (34/11 10. 12/11 1211 (12/11 45. 5211 52/11 (52/114 88. 46/5 465 (46/5 7. 4/5 (4/5 1. 1/5 15 (1/5 [OR 4. 1.62–14. 16214 0.00 000 00 6.6 66 2.04–21. 20421 ±13 (±13 86/1 861 (86/1 34/1 341 (34/1 12/1 121 (12/1 521 52/1 (52/11 46/ (46/ 4/ (4/ 1/ (1/ 1.62–14 1621 0.0 6. 2.04–21 2042 ±1 (±1 86/ (86/ 34/ (34/ 12/ (12/ 52/ (52/1 (46 (4 (1 1.62–1 162 0. 2.04–2 204 ± (± (86 (34 (12 (52/ ( 1.62– 16 2.04– 20 (8 (3 (52 1.62 2.04 (5 1.6 2.0 2.
Resumo Antecedentes Apesar de estudos prévios indicarem uma incidência moderada/alta de cefaleia da angiografia (CA), os dados sobre os fatores de risco associados à sua ocorrência ainda são relativamente escassos. Objetivo O presente estudo teve como objetivo avaliar as associações entre as características demográficas, clínicas e técnicas da angiografia cerebral por subtração digital (ACSD) e a ocorrência de CA. Métodos Estudo observacional analítico transversal com uma amostra composta por indivíduos com indicação de ACSD em caráter eletivo. Entrevistas clínicas foram realizadas utilizando um questionário padronizado para acessar a ocorrência de CA. Resultados Entre os 114 indivíduos, a idade média foi de 52,8 (±13,8) anos, 75,4% (86/114) eram mulheres, 29,8% (34/114) tinham histórico de enxaqueca e 10,5% (12/114) tinham cefaleia crônica. A frequência geral de CA foi de 45,6% (52/114). Desses, 88,4% (46/52) foram submetidos à angiografia 3D, 7,7% (4/52), à aortografia e 1,9% (1/52), aos dois procedimentos. Houve associação estatisticamente significativa entre CA e histórico prévio de enxaqueca (odds ratio [OR] 4,9; intervalo de confiança [IC] 95%: 1,62–14,7; p = 0,005) e angiografia 3D (OR 6,62; IC95%: 2,04–21,5; p = 0,002). Conclusões A angiografia 3D está fortemente associada à ocorrência de CA, o que é inédito na literatura. A associação entre um histórico de enxaqueca e a CA confirma os resultados de estudos anteriores. moderadaalta moderada alta , (CA) escassos demográficas (ACSD eletivo 11 528 52 8 52, ±13,8 138 13 (±13,8 anos 754 75 4 75,4 86/114 86114 86 (86/114 mulheres 298 29 29,8 34/114 34114 34 (34/114 105 10 5 10,5 12/114 12114 12 (12/114 crônica 456 45 6 45,6 52/114. 52114 52/114 . (52/114) Desses 884 88 88,4 46/52 4652 46 (46/52 D 77 7 7,7 4/52, 452 4/52 (4/52) 19 1 9 1,9 1/52, 152 1/52 (1/52) procedimentos odds OR [OR 4,9 49 IC [IC 95% 95 1,62–14,7 162147 62 14 0,005 0005 0 005 6,62 662 IC95% IC95 2,04–21,5 204215 2 04 21 0,002. 0002 0,002 002 0,002) literatura anteriores (CA ±13, (±13, 75, 86/11 8611 (86/11 29, 34/11 3411 3 (34/11 10, 12/11 1211 (12/11 45, 5211 52/11 (52/114 88, 46/5 465 (46/5 7, 4/5 (4/52 1, 15 1/5 (1/52 4, 1,62–14, 16214 0,00 000 00 6,6 66 IC9 2,04–21, 20421 ±13 (±13 86/1 861 (86/1 34/1 341 (34/1 12/1 121 (12/1 521 52/1 (52/11 46/ (46/ 4/ (4/5 1/ (1/5 1,62–14 1621 0,0 6, 2,04–21 2042 ±1 (±1 86/ (86/ 34/ (34/ 12/ (12/ 52/ (52/1 (46 (4/ (1/ 1,62–1 162 0, 2,04–2 204 ± (± (86 (34 (12 (52/ (4 (1 1,62– 16 2,04– 20 ( (8 (3 (52 1,62 2,04 (5 1,6 2,0 2,