The use of materials such as organofunctionalized silica for application in solid phase extraction (SPE) allows the preconcentration of several ions, including Pt, and subsequent detection. This work aims to synthesize and characterize an organofunctionalized silica (Sil-TMSDT) with the silylant N’(trimethoxysilyl)propylethylenetriamine and its application as a solid phase in the preconcentration Pt4+ ions in aqueous media, using detection by flame atomization atomic absorption spectroscopy (FAAS). The Fourier-transform infrared spectroscopy (FTIR) spectra and scanning electron microscopy (SEM) coupled with energy-dispersive spectroscopy (EDS) confirmed the aminofunctionalization of the silica. For the adsorption process, a preconcentration mini-column with 200 mg of Sil-TMSDT, a solution of 0.485 mg L−1 of K2[PtCl6] at pH 10 and HNO3 0.5 mol L−1 as eluent were used, obtaining an enrichment factor of 15-fold with retention efficiency higher than 99%. The Pt4+ ion determined by FAAS showed a linear response between 0.02 and 0.40 mg L−1; a linear coefficient where R = 0.9981; a 16-fold preconcentration factor; a limit of quantification (LOQ) and limit of detection (LOD) of 0.045 and 0.014 mg L−1, respectively. The proposal system showed analytical applicability to determining Pt4+ ion in an aqueous medium and could be used to detect traces of this potentially toxic metal in biological fluids such as urine and blood. SPE (SPE Pt SilTMSDT Sil TMSDT (Sil-TMSDT Ntrimethoxysilylpropylethylenetriamine N trimethoxysilyl propylethylenetriamine Pt4 media FAAS. . (FAAS) Fouriertransform Fourier transform FTIR (FTIR SEM (SEM energydispersive energy dispersive EDS (EDS process minicolumn mini column 20 SilTMSDT, TMSDT, Sil-TMSDT 0485 0 485 0.48 L1 L 1 L− K2PtCl6 KPtCl K2 PtCl6 K PtCl K2[PtCl6 HNO 05 5 0. 15fold fold 15 99 99% 002 02 0.0 040 40 0.4 0.9981 09981 9981 16fold 16 LOQ (LOQ LOD (LOD 0045 045 0.04 0014 014 0.01 respectively blood (FAAS 2 048 48 K2PtCl K2[PtCl 9 00 04 4 0.998 0998 998 004 001 01 0.99 099 0.9 09

Parthenolide (PTN) is a secondary metabolite of the plant Tanacetum parthenium (L.) Schulz Bip. and is considered the chemical marker of this species. This sesquiterpene lactone (germacrene skeleton) has been described as responsible for the biological activity of the leaf extract. In addition, several studies in the literature have demonstrated its antiparasitic and antineoplastic activity. However, there is a need for knowledge of other safety parameters, such as pharmacokinetic, pharmacodynamic and toxicity evaluations. Therefore, in this investigation, the in vitro metabolism of parthenolide was performed with rat liver microsomes and biomimetic metabolism (such as cytochrome P-450 system) using organometallic catalysts. The biomimetic procedure was validated since the major compound of biomimetic oxidative reaction with meta-chloroperbenzoic acid catalyzed by metalloporphyrin 5,10,15,20-tetrakis(pentafluorophenyl)-porphyrin iron(III) chloride was also observed with rat liver microsomes. Previous chemoenzymatic synthesis studies of PTN afforded the same epoxide formation, this major oxidative compound was isolated and fully characterized as (1 R,10R)-epoxyparthenolide based on experimental and theoretical calculations of infrared (IR) and vibrational circular dichroism (VCD) data at the B3PW91/6-311G. Furthermore, for the first time, this metabolite was evaluated for trypanocidal and leishmanicidal activity. The mean inhibitory concentration (IC50) values were lower for PTN than its metabolite and showed significant cytotoxic effects for both parasites. This finding holds promise for addressing neglected diseases. (PTN L. L (L. Bip species germacrene skeleton extract addition However parameters pharmacokinetic evaluations Therefore investigation P450 P 450 P-45 system catalysts metachloroperbenzoic meta chloroperbenzoic 5,10,15,20tetrakispentafluorophenylporphyrin 5101520tetrakispentafluorophenylporphyrin tetrakispentafluorophenylporphyrin 5,10,15,20 tetrakis pentafluorophenyl porphyrin 5 10 15 20 ironIII iron III iron(III formation 1 ( R,10Repoxyparthenolide R10Repoxyparthenolide RRepoxyparthenolide R,10R epoxyparthenolide R 10R IR (IR VCD (VCD B3PW91/6311G. B3PW916311G BPWG B3PW91/6 311G. B3PW91 6 311G B PW G B3PW91/6-311G Furthermore time IC50 IC (IC50 parasites diseases (L P45 45 P-4 20tetrakispentafluorophenylporphyrin 5101520 5,10,15,2 2 10Repoxyparthenolide Repoxyparthenolide R10R RR 6311G B3PW91/6311G B3PW916 BPW B3PW91/ B3PW9 IC5 (IC5 P4 4 P- 510152 5,10,15, B3PW (IC 51015 5,10,15 5101 5,10,1 510 5,10, 51 5,10 5,1 5,

ABSTRACT The estimation of evapotranspiration (ET) and crop water requirements are crucial for the proper management and allocation of water resources in terms of quantity, quality, and timeliness. Therefore, remote sensing estimation of ET using the SEBAL algorithm (Surface Energy Balance Algorithm for Land) can provide spatio-temporal, non-punctual data, unlike traditional calculations relying on the nearest meteorological station. This research analyzed ET using SEBAL, based on ten Landsat 8 satellite images processed with a program developed in the Model Builder of ArcGis® version 10.2. The analysis was conducted during the vegetative period of starchy corn from May to October 2016. Validation of the results happened with a drainage lysimeter installed in a monitoring plot. Additionally, the statistical indices - such as percentage relative error (PRE) (0,09), root mean square error (RMSE) (0,30), R2 (0,92), and Nash-Sutcliffe efficiency (NASH) (0,91) - indicated a good correlation of ET for starchy corn in the central highlands of Peru. The ET identified at ten monitoring points ranged from 1,05 to 7,79 mm d-1. (ET quantity quality timeliness Therefore Surface Land spatiotemporal, spatiotemporal spatio temporal, temporal spatio-temporal nonpunctual non punctual data station ArcGis 102 10 2 10.2 2016 plot Additionally PRE (PRE 0,09, 009 0,09 , 0 09 (0,09) RMSE (RMSE 0,30, 030 0,30 30 (0,30) R 0,92, 092 0,92 92 (0,92) NashSutcliffe Nash Sutcliffe NASH (NASH 0,91 091 91 (0,91 Peru 105 1 05 1,0 779 7 79 7,7 d1. d1 d 1. d-1 10. 201 00 0,0 (0,09 03 0,3 3 (0,30 0,9 9 (0,92 (0,9 1, 77 7, d- 20 0, (0,0 (0,3 (0, (0 (

ABSTRACT Given the large differences in the results of inoculation and co-inoculation in the bean crop, an experiment in cultivating winter beans was carried out in 2019 under greenhouse conditions with the aim of evaluating the performance of the beans and a possible increase in plant growth and grain production, using seeds inoculated or co-inoculated with Rhizobium tropici and Azospirillum brasilense, with and without fungicide and/or insecticide, in sandy and clayey soils. A total of 112 pots were used, and 14 treatments were applied in a completely randomised experimental design, with four replications. The Scott-Knott test was used to analyse the results, and showed that whether using untreated seeds or carrying out complete chemical treatment with fungicide and insecticide plus co-inoculation with R. tropici and A. brasilense, winter bean production was reduced in clayey soil, while the joint use of fungicide and insecticide, fungicide and R. tropici, or fungicide, insecticide and R. tropici, favoured shoot development. Inoculating with A. brasilense, without R. tropici and with insecticide, or insecticide and fungicide, favoured greater root growth in clayey soil. In sandy soil, grain production was higher using seeds treated solely with insecticide, solely with R. tropici, or with a combination of both. Production was lower in the joint treatment with fungicide, insecticide and the co-inoculation of bacteria, or when using insecticide together with A. brasilense. coinoculation co crop 201 coinoculated brasilense andor soils 11 1 design replications ScottKnott Scott Knott R soil development both bacteria 20 2

This paper presents the stages of an acceleration program focused on chemical technologies. We demonstrate how this initiative contributes to the creation of new businesses, startups, and technology licensing from research developed at Brazilian universities. The case of the program Escale-se is discussed. There were 66 technologies submitted, and 14 were selected for the pre-acceleration phase. In this phase, various contents were worked on, such as creating a business model and aspects of scaling hard-science technologies. Teams were evaluated by panels with market specialists, and 6 were selected for the second phase: pre-scaling/proof of concept. Here, proponents were encouraged to validate the business model by connecting with potential clients and partners, as well as planning the development and testing of the product in a relevant environment. Finally, one team was classified for the last stage: scaling/go-to-market - where they received R$ 100,000.00 to scale up their technology and create strategies for raising investments. Four of the fourteen technologies selected for the program opened National Register of Legal Entities (CNPJ) and raised approximately R$ 4.5 M in investments from different sources. These results demonstrate that the methodology contributed to the entrepreneurial development of participating researchers and the raising of funds for the businesses created. startups universities Escalese Escale se discussed submitted 1 preacceleration pre phase hardscience hard science specialists prescaling/proof prescalingproof scaling/proof proof concept Here partners environment Finally stage scaling/gotomarket scalinggotomarket scaling/go go R 10000000 100 000 00 100,000.0 CNPJ (CNPJ 45 4 5 4. sources created prescaling scalingproof gotomarket scalinggo 1000000 10 0 100,000. 100000 100,000 10000 100,00 1000 100,0 100,

The increase in the average temperature of the Earth due to excess CO2 and other greenhouse gases has caused glaciers to melt and sea levels to rise. The burning of fossil fuels is one of the main causes of this problem, so the use of biofuels is important for mitigating this environmental impact. In Brazil, biodiesel is mixed with mineral; however, irregularities have been detected, reducing the expected positive effects. Therefore, this study proposes the use of multivariate curve resolution with alternating least squares (MCR ALS) to quantify the content of methyl palm oil biodiesel in diesel blends and determine the concentration of the adulterant automotive lubricating oil in the blend. The model for quantifying biodiesel in diesel obtained R2 = 0.9997, root mean square error of calibration (RMSEC) = 0.56% (v v-1) and prediction (RMSEP) = 0.65% (v v-1), while the determination of adulteration in the biodiesel-diesel blend showed RMSEC = 0.67% (v v-1), RMSEP = 0.81% (v v-1) and R2 = 0.9992. These results demonstrate the ability of the models developed to predict both the content and quantity of possible adulterants in blends of palm oil biodiesel and mineral diesel, contributing to the quality control of this fuel. CO rise problem impact Brazil however detected effects Therefore MCR ALS R 09997 0 9997 0.9997 (RMSEC 056 56 0.56 v v1 1 v-1 (RMSEP 065 65 0.65 v1, , biodieseldiesel 067 67 0.67 081 81 0.81 09992 9992 0.9992 fuel 0999 999 0.999 05 5 0.5 v- 06 6 0.6 08 8 0.8 099 99 0.99 0. 09 9 0.9

RESUMO Objetivo: Avaliar a correlação entre a religiosidade e o uso de álcool em adolescentes com fissura orofacial. Métodos: Estudo transversal, desenvolvido em um hospital público e terciário brasileiro entre dezembro de 2021 e março de 2022. A coleta de dados foi híbrida, e foram utilizados três instrumentos: Questionário Sociodemográfico, Escala de Religiosidade de Durel e o Alcohol Use Disorders Identification Test. Para a análise estatística foram empregados os testes: qui-quadrado, exato de Fisher, Mann-Whitney e o coeficiente de correlação de Spearman, além das análises de forças de correlação linear e de regressão logística bivariada. O nível de significância adotado para todos os testes foi de 5% (p≤0,05). Resultados: Participaram 370 adolescentes, com média de idade de 15,2 anos (±1,8). Entre eles, 23 (5,4%) usavam o álcool de forma arriscada ou prejudicial. A religiosidade organizacional, não organizacional e a intrínseca foram significativamente menos frequentes entre adolescentes que utilizavam o álcool de forma arriscada ou prejudicial (p=0,005; p<0,001 e p=0,002, respectivamente). Evidenciou-se correlação moderada entre o uso arriscado ou prejudicial do álcool e a religiosidade não organizacional (r=0,31; p=0,002) e a intrínseca (r=0,36; p<0,001). Apresentaram maiores chances de usar o álcool adolescentes do sexo masculino (p<0,001; odds ratio — OR=6,58), com idade mais próxima aos 18 anos (p<0,001; OR=1,37) e que não praticavam a religião (p<0,001; OR=6,48). Conclusões: Adolescentes com maiores níveis de religiosidade organizacional e intrínseca utilizaram menos frequentemente álcool de forma arriscada ou prejudicial, enquanto ser homem, possuir idade mais próxima aos 18 anos e não praticar a religião aumentou a chance de utilizar álcool. Objetivo orofacial Métodos transversal 202 2022 híbrida instrumentos Sociodemográfico Test quiquadrado, quiquadrado qui quadrado, quadrado qui-quadrado Fisher MannWhitney Mann Whitney Spearman bivariada 5 p≤0,05. p005 p p≤0,05 . 0 05 (p≤0,05) Resultados 37 152 15 2 15, ±1,8. ±1,8 1 8 (±1,8) eles 5,4% 54 4 (5,4% p=0,005 p0005 005 (p=0,005 p0001 001 p<0,00 p0002 002 p=0,002 respectivamente. respectivamente respectivamente) Evidenciouse Evidenciou se r=0,31 r031 r 31 (r=0,31 r=0,36 r036 36 (r=0,36 p<0,001. p<0,001) (p<0,001 OR=6,58, OR658 OR OR=6,58 , 6 58 OR=6,58) OR=1,37 OR137 OR=6,48. OR648 OR=6,48 48 OR=6,48) Conclusões homem 20 p00 p≤0,0 (p≤0,05 3 ±1, (±1,8 5,4 (5,4 p=0,00 p000 00 (p=0,00 p<0,0 r=0,3 r03 (r=0,3 (p<0,00 OR65 OR=6,5 OR=1,3 OR13 OR64 OR=6,4 p0 p≤0, (p≤0,0 ±1 (±1, 5, (5, p=0,0 (p=0,0 p<0, r=0, r0 (r=0, (p<0,0 OR6 OR=6, OR=1, OR1 p≤0 (p≤0, ± (±1 (5 p=0, (p=0, p<0 r=0 (r=0 (p<0, OR=6 OR=1 p≤ (p≤0 (± ( p=0 (p=0 p< r= (r= (p<0 OR= (p≤ p= (p= (r (p< (p

ABSTRACT Objective: To evaluate the correlation between religiosity and alcohol use among adolescents with orofacial clefts. Methods: Cross-sectional study, developed in a Brazilian public and tertiary hospital, between December 2021 and March 2022. Data collection was hybrid, and three instruments were used: Sociodemographic Questionnaire, Durel Religiosity Scale, and the Alcohol Use Disorders Identification Test. For statistical analysis, the following tests were used: χ2, Fisher’s Exact, Mann-Whitney and Spearman’s Correlation Coefficient, in addition to analyses of linear correlation strength and bivariate logistic regression. The significance level adopted for all tests was 5% (p≤0.05). Results: 370 adolescents participated, with a mean age of 15.2 years (±1.8). Among them, 23 (5.4%) used alcohol riskly or harmfully, being more frequent among male adolescents (p=0.001), those of mixed race (p=0.046), attending high school (p=0.011), with no religion (p<0.001), or who did not attend religious services (p<0.001). Levels of organizational, non-organizational and intrinsic religiosity were significantly lower among adolescents with risky or harmful alcohol use (p=0.005; p<0.001 and p=0.002, respectively). There was a moderate correlation between risky or harmful alcohol use and non-organizational (r=0.31; p=0.002) and intrinsic (r=0.36; p<0.001) religiosity. Male adolescents (p<0.001; OR=6.58), closest in age to 18 years (p<0.001; OR=1.37), and non-practitioners of religion (p<0.001; OR=6. 48) presented higher odds of risky or harmful alcohol use. Conclusions: Adolescents with higher levels of organizational and intrinsic religiosity used less alcohol, while males, closest in age to 18 years, and non-practitioners of religion presented higher odds of using alcohol riskly or harmfully. Objective clefts Methods Crosssectional Cross sectional study hospital 202 2022 hybrid Questionnaire Scale Test analysis χ2 χ Fishers Fisher s Exact MannWhitney Mann Whitney Spearmans Spearman Coefficient regression 5 p≤0.05. p005 p p≤0.05 . 0 05 (p≤0.05) Results 37 participated 152 15 2 15. ±1.8. ±1.8 1 8 (±1.8) them 5.4% 54 4 (5.4% harmfully p=0.001, p0001 p=0.001 , 001 (p=0.001) p=0.046, p0046 p=0.046 046 (p=0.046) p=0.011, p0011 p=0.011 011 (p=0.011) p<0.001, (p<0.001) p<0.001. nonorganizational non p=0.005 p0005 005 (p=0.005 p<0.00 p0002 002 p=0.002 respectively. respectively respectively) r=0.31 r031 r 31 (r=0.31 r=0.36 r036 36 (r=0.36 (p<0.001 OR=6.58, OR658 OR OR=6.58 6 58 OR=6.58) OR=1.37, OR137 OR=1.37 OR=1.37) nonpractitioners practitioners OR6 OR=6 48 Conclusions males 20 p00 p≤0.0 (p≤0.05 3 ±1. (±1.8 5.4 (5.4 p000 p=0.00 00 (p=0.001 p004 p=0.04 04 (p=0.046 p001 p=0.01 01 (p=0.011 (p=0.00 p<0.0 r=0.3 r03 (r=0.3 (p<0.00 OR65 OR=6.5 OR13 OR=1.3 OR= p0 p≤0. (p≤0.0 ±1 (±1. 5. (5. p=0.0 (p=0.04 (p=0.01 (p=0.0 p<0. r=0. r0 (r=0. (p<0.0 OR1 OR=1. p≤0 (p≤0. ± (±1 (5 p=0. (p=0. p<0 r=0 (r=0 (p<0. OR=1 p≤ (p≤0 (± ( p=0 (p=0 p< r= (r= (p<0 (p≤ p= (p= (r (p< (p

This study expands and shows the versatility of applications in hydrophilic interaction chromatography coupled with triple quadrupole mass spectrometry (HILIC-MS/MS) using a FRULIC-N column to determine 31 phenolic compounds in beverage industry residues (coffee, apple juice, beer, and wine). Optimization, via Doehlert design, determined the acetonitrile proportion (50-90%) and pH (3.0-7.0) in the mobile phase (MP). A 22 factorial design assessed the concentration of ammonium acetate (10-110 mmol L-1) in the MP and column temperature (20-60 °C). Injection volume (5-45 µL) was univariately optimized. Separations at 60 °C reduced chromatographic run time to less than 11 min. Gradient elution (500 µL min-1) employed an MP comprising acetonitrile and ammonium acetate (110 mmol L-1, pH 7). Validation demonstrated average coefficient of determination (R2) 0.9707, limit of detection 0.001-0.503 mg L-1 and quantification 0.004-1.524 mg L-1, precision < 12.2%, recovery 92.4-110.8%. The method was applied to five residues, indicating its viability for determining phenolics in beverage production residues. HILICMS/MS HILICMSMS HILIC MS/MS MS (HILIC-MS/MS FRULICN FRULIC N 3 coffee, coffee (coffee juice beer wine. wine . wine) Optimization 5090% 5090 50 90% 90 (50-90% 3.07.0 3070 3.0 7.0 0 7 (3.0-7.0 MP. (MP) 2 10110 10 110 (10-11 L1 L 1 2060 20 (20-6 °C. C °C) 545 5 45 (5-4 optimized 6 min 500 (50 min1 min-1 (11 L1, 1, 7. 7) R2 R (R2 09707 9707 0.9707 0.0010.503 00010503 0.001 0.503 001 503 0.001-0.50 L- 0.0041.524 00041524 0.004 1.524 004 524 0.004-1.52 122 12 12.2% 92.4110.8%. 9241108 92.4 110.8%. 92 4 8 92.4-110.8% HILICMS MSMS 509 9 (50-90 07 3.07. 307 30 3. 70 (3.0-7. (MP 1011 (10-1 206 (20- 54 (5- (5 min- (1 (R 0970 970 0.970 0010 0.0010.50 0001050 0001 0.00 0503 0.50 00 0.001-0.5 0041 0.0041.52 0004152 0004 1524 1.52 52 0.004-1.5 12.2 4110 92.4110.8% 924110 924 92. 1108 110.8% 92.4-110.8 (50-9 3.07 (3.0-7 101 (10- (20 ( 097 97 0.97 0.0010.5 000105 000 0.0 050 0.5 0.001-0. 0.0041.5 000415 152 1.5 0.004-1. 12. 411 92.4110.8 92411 110.8 92.4-110. (50- (3.0- (10 (2 09 0.9 0.0010. 00010 0. 05 0.001-0 0.0041. 00041 15 1. 0.004-1 41 92.4110. 9241 110. 92.4-110 (3.0 0.0010 0.001- 0.0041 0.004- 92.4110 92.4-11 (3. 92.411 92.4-1 (3 92.41 92.4-

Methods used to determine pesticide residues in teas typically require several laborious steps for sample preparation before analysis. In this study, a simple method based on solid-liquid extraction with low-temperature partitioning (SLE/LTP) and analysis by gas chromatography coupled to mass spectrometry (GC-MS) was optimized and validated for the determination of pesticide residues (pirimiphos-methyl, flutriafol, cyproconazole, and bifenthrin) in dehydrated green tea leaves. After low-temperature partitioning (LTP), the extract in acetonitrile was subjected to a clean-up step using primary secondary amine (PSA) and octadecylsilane (C18) as sorbents for chlorophyll removal. The optimized SLE/LTP-GC-MS method was validated, and it proved to be effective and selective for extracting pesticides from green tea samples, presenting limit of detection (LOD) and limit of quantification (LOQ) of 0.015 and 0.050 mg kg-1, respectively. Recovery ranged between 81-111%, coefficients of variation were less than 16% and coefficients of determination (R2) were greater than 0.990. The optimized and validated method was applied to green tea and 13 other tea varieties sampled in South and Southeast regions of Brazil. The pesticides under study were detected in some of those samples at values higher than the maximum residue limits (MRLs) allowed by the European Union. solidliquid solid liquid lowtemperature low temperature SLE/LTP SLELTP SLE LTP (SLE/LTP GCMS GC MS (GC-MS pirimiphosmethyl, pirimiphosmethyl pirimiphos methyl, methyl (pirimiphos-methyl flutriafol cyproconazole bifenthrin leaves LTP, , (LTP) cleanup clean up PSA (PSA C18 C (C18 removal SLE/LTPGCMS SLELTPGCMS LOD (LOD LOQ (LOQ 0015 0 015 0.01 0050 050 0.05 kg1, kg1 kg 1, 1 kg-1 respectively 81111%, 81111 81 111%, 111 81-111% 16 R2 R (R2 0990 990 0.990 Brazil MRLs (MRLs Union (LTP C1 (C1 LTPGCMS 001 01 0.0 005 05 kg- 81111% 8111 8 111% 11 81-111 (R 099 99 0.99 (C 00 0. 811 81-11 09 9 0.9 81-1 81-

Iron is an important ion that regulates many metabolic functions in the human body, and its deficiency or overload can cause serious health problems. In view of this, the development of tools that can quantify iron in aqueous media is quite valuable. A new material based on a metal-organic framework (MOF) and a calixarene derivative (CALIX), here named CALIX@UiO-66-NH2, was successfully prepared and used as a luminescent sensor for iron ions in a water matrix containing various metal ions. The post-synthetic modification was demonstrated to be efficient on the MOF (UiO-66-NH2) modification, leading to a hybrid platform. The effect of the combination of both components (MOF and CALIX) led to a platform more sensitive to iron detection than the independent compounds. The CALIX@UiO-66-NH2 sensor shows a linear response toward Fe3+ ions with satisfactory linearity (R2 = 0.994) within the concentration range of 6.74 × 10−6−1.72 × 10−5 mol L−1. The limit of detection was determined to be as low as 1.6 mg L−1. The data demonstrate that CALIX@UiO-66-NH2 is an excellent probe for detecting Fe3+, as confirmed by almost complete fluorescence suppression. body problems this valuable metalorganic organic CALIX, CALIX , (CALIX) CALIX@UiO66NH2, CALIXUiO66NH2 CALIXUiONH CALIX@UiO 66 NH2, UiO NH2 NH postsynthetic post synthetic UiO66NH2 UiONH (UiO-66-NH2 compounds CALIX@UiO66NH2 CALIX@UiO-66-NH Fe3 Fe R2 R (R 0.994 0994 0 994 674 6 74 6.7 106172 10 1 72 10−6−1.7 105 5 10− L1 L L−1 16 1. suppression (CALIX CALIXUiO CALIXUiO66NH UiO66NH (UiO-66-NH CALIX@UiO66NH 0.99 099 99 67 7 6. 10617 10−6−1. L− 0.9 09 9 1061 10−6−1 0. 106 10−6− 10−6

Electrooxidation is an efficient method for treating effluents with high concentrations of ammoniacal nitrogen and organic matter (R), in the presence of chloride ions (Cl-). The present study aimed at degrading ammoniacal nitrogen and organic matter from an effluent generated at a fertilizer storage port terminal. For this purpose, a batch electrochemical reactor with mechanical agitation was used, with a Ti/RuO2 anode. The parameters studied were the current density that varied in 20, 40 and 60 mA cm-2, the concentration of chloride ions that was 0.04, 0.74, 0.90 to 0.81 mol L-1 and the electrolysis time that varied from 4.0, 5.0, 7.0 and 8.0 h. A 22 experimental design was conducted to determine the significance level of the parameters studied. The results obtained indicated the removal of 99.99% of N-NH3 and 75.60% of total organic carbon (TOC) when a current density of 60 mA cm-2 and a Cl- concentration of 35.5 g L-1 were applied, after 4.0 h of electrolysis. R, R , (R) Cl. Cl . (Cl-) terminal purpose used TiRuO2 TiRuO Ti RuO2 RuO Ti/RuO anode 20 4 6 cm2, cm2 cm 2, 2 004 0 04 0.04 074 74 0.74 090 90 0.9 081 81 0.8 L1 L 1 L- 50 5 5.0 70 7 7. 80 8 8. 9999 99 99.99 NNH3 NNH N NH3 NH N-NH 7560 75 75.60 TOC (TOC cm- 355 35 35. applied 4. (R (Cl- 00 0.0 07 0.7 09 9 0. 08 5. 999 99.9 756 75.6 3 (Cl 99. 75.

ABSTRACT This study aimed to explore the friction force on potatoes in the process of potato-soil separation, its influencing factors and laws, and establish a testing system of potato-friction force. It was verified that the potato mass, crank speed, and sieve inclination significantly affected the potato’s friction force along the sieve surface. The interaction of potato mass and crank speed had the greatest effect on the friction force on the potato along the sieve surface. In addition, under the same factors of potato mass of 200~400 g, crank speed of 200 r min-1, and sieve inclination of 14.7°, the friction force of potato along the sieve surface with soil was much greater than that along the sieve surface without soil, ranging between 2.32 and 4.85. potatosoil separation laws potatofriction potatos s addition 200400 400 200~40 g 20 min1, min1 min 1, 1 min-1 147 14 7 14.7° 232 2 32 2.3 485 4 85 4.85 20040 40 200~4 min- 14.7 23 3 2. 48 8 4.8 2004 200~ 14. 4.

RESUMO O presente estudo visou investigar a força de atrito durante o processo de separação da batata do solo, bem como os fatores e padrões que influenciam essa força, além de estabelecer um sistema de teste para medir a força de atrito das batatas. Verificou-se que a massa da batata, a velocidade da manivela e a inclinação da peneira têm um impacto significativo na força de atrito ao longo da superfície da peneira. A interação entre a massa da batata e a velocidade da manivela tem o maior impacto na força de atrito ao longo da superfície da peneira. Além disso, sob os mesmos fatores - massa da batata entre 200-400 g, velocidade da manivela em 200 r min-1 e ângulo inclinado da peneira em 14.7°, a força de atrito das batatas ao longo da superfície com o solo é muito maior do que ao longo da superfície sem solo, variando entre 2,32 e 4,85. Verificouse Verificou se disso 200400 400 200-40 g 20 min1 min 1 min- 147 14 7 14.7° 232 2 32 2,3 485 4 85 4,85 20040 40 200-4 14.7 23 3 2, 48 8 4,8 2004 200- 14. 4,

Resumen Marco contextual: Los teléfonos móviles inteligentes permiten acceder a información de manera inmediata. La adicción al uso de estos dispositivos es cada vez mayor, los teléfonos móviles inteligentes se han convertido en un elemento importante para los estudiantes de enfermería. Objetivo: Identificar la adicción al uso del teléfono móvil inteligente en estudiantes de enfermería. Metodología: Estudio descriptivo correlacional, el muestreo fue aleatorio, la muestra se calculó considerando un nivel de confianza de 0,05, una potencia de 90%, un tamaño de efecto mediano de 0,09, la muestra se conformó por 149 estudiantes de enfermería. Resultados: El componente de uso, abuso y adicción al teléfono móvil inteligente se relacionó negativamente con el componente rasgo de personalidad (r s = -0,228; p = 0,005), el uso, abuso y adicción al teléfono móvil inteligente se relacionó positivamente con el gasto monetario (r s = 0,376; p = 0,001). Conclusión: Se identificó que existe un alto uso de los teléfonos móviles inteligentes, comprender el alcance de dicho fenómeno puede ayudar a plantear estrategias eficaces para prevenir la adicción al teléfono móvil inteligente.

Resumo Enquadramento: Os telemóveis inteligentes estão permitem acesso imediato à informação. O vício no uso desses dispositivos é cada vez maior, os celulares inteligentes tornaram-se um elemento importante para os estudantes de enfermagem. Objetivo: Identificar a dependência do uso do smartphone em estudantes de enfermagem. Metodologia: Estudo correlacional descritivo, a amostragem foi aleatória, a amostra foi calculada considerando nível de confiança de 0,05, poder de 90%, tamanho de efeito médio de 0,09, a amostra foi composta por 149 estudantes de enfermagem. Resultados: O componente de uso, abuso e dependência de smartphone foi negativamente relacionado ao componente de traço de personalidade (r s = -0,228; p = 0,005), o uso, abuso e dependência de smartphone foi relacionado positivamente com gastos monetários (r s = 0,376; p = 0,001). Conclusão: Identificou-se que existe um alto uso de telefones móveis inteligentes, compreender a abrangência desse fenômeno pode ajudar a propor estratégias eficazes para prevenir o vício em celulares.

Abstract Background: Smartphones provide immediate access to information, and nursing students consider them essential tools. However, the addiction to these devices is increasing. Objective: To identify smartphone addiction among nursing students. Methodology: A descriptive correlational study was conducted using the stratified random sampling method. The sample size was calculated based on a confidence level of 0.05, with 90% power, and a median effect size of 0.09. The study included 149 nursing students. Results: The component “Smartphone use, abuse, and addiction” correlated negatively with the component “Personality traits” (r s = -0.228; p = 0.005); the component “Smartphone use, abuse, and addiction” correlated positively with the component “Financial spending” (r s = 0.376; p = 0.001). Conclusion: Smartphone use is high. Understanding the extent of this phenomenon can aid in developing effective strategies to prevent smartphone addiction.

ABSTRACT Introduction: the postgraduate educational climate (CE) in the hospital environment can determine the way in which resident physicians (MRs) adapt to their new stage, during which professional burnout syndrome (PAS) is highly likely to occur at some point. Objective: to determine the relationship between the educational climate and professional burnout in physicians in the medical residency programs of the National Hospital 2023-2024. Methodology: cross-sectional observational study of a sample of MR convenience of both sexes from all medical specialties of the National Hospital between November 2023 and January 2024, MR with external rotation and/or vacations were excluded. Sample calculation; 136 MR. An online form from Google was sent to the MR email requesting voluntary participation. The SAP was measured with the standard Maslach Burnout Inventory (MBI) method with subscales; emotional exhaustion (EA), depersonalization (DESP), personal fulfillment (PR), with PAS with high scores of AE, DESP and low RP. The EC was assessed with the measure of the hospital postgraduate educational environment (PHEEM) with subscales; perception of role autonomy (PAR), perception of teaching (PE), perception of social support (PSS), the higher the score, the better the EC. Demographic and academic variables, MBI and PHEEM scores were collected, and the SAP was considered dependent, as the main result was the predictive relationship of the PHEEM on the SAP. Data were compared with χ², t-test or Mann-Whitney U, ANOVA and linear regression (p-significant value =<0.05). Results: of 233 participants, the mean age was 28.75 (±2.20), 63.94 % (149) women, the general prevalence of PAS; 70.38 % (164/233), PAS in men 75 % (63/84) and women 67.78 % (101/149) p=0.0014, the first 2 years with the highest frequency of PAS; 65 (85.52 %), 59 (86.76 %) respectively p=0.0009, 63 (90 %) p=0.0071 surgical specialties. The subscales of the MBI, the AE; 79.82 % (186) with an average of 35.39 (± 11.61) points. The CE of MRs with SAP; 107.9 (19.6) dots and without PAS; 136.3 (12.1) dots 95 % CI 18.1-25.0 p= 0.0001. The PHEEM predicted the AE with R2=0.619, B= -0.18 (±0.009) p=0.001, and the DESP; R2= 0.385, B= -0.001(0.004) p=0.009, PSS being a significant predictor with inverse correlation in both. Conclusion: there is an inverse relationship between the educational climate and burnout syndrome in the population studied, with a high prevalence of burnout in male residents of surgical specialties, with the social support of the hospital educational environment being a significant predictor for the development of burnout syndrome.

RESUMEN Introducción: el clima educacional (CE) de posgrado en el ambiente hospitalario puede determinar la manera en como los médicos residentes (MR) se adaptan a su nueva etapa, durante el cual el sindrome agotamiento profesional (SAP) es altamente probable de producirse en algún momento. Objetivo: determinar la relación entre el clima educacional y el agotamiento profesional en médicos de los programas de residencias médicas del Hospital Nacional 2023-2024. Metodología: estudio observacional transversal de una muestra por conveniencia de MR de ambos sexos de todas las especialidades médicas del Hospital Nacional entre noviembre 2023 y enero 2024, se excluyeron MR con rotación externa y/o vacaciones. Calculo muestral; 136 MR. Se envío un formulario en línea de Google al correo electrónico del MR solicitando la participación voluntaria. El SAP fue medido con el método estándar Maslach Burnout Inventory (MBI) con subescalas; agotamiento emocional (AE), despersonalización (DESP), realización personal (RP), existiendo SAP con puntuaciones altas de AE, DESP y bajas de RP. El CE fue valorado con la medida del entorno educativo de posgrado hospitalario (PHEEM) con subescalas; percepción autonomía de roles (PAR), percepción enseñanza (PE), percepción soporte social (PSS), a mayor puntaje mejor CE. Se recopiló variables demográficos, académicos, puntajes del MBI y PHEEM, el SAP fue considerado dependiente, como resultado principal la relación predictiva del PHEEM sobre el SAP. Se compararon datos con χ², prueba t o U de Mann-Whitney, ANOVA y regresión lineal (p-valor significativo =<0,05). Resultados: de 233 participantes, la edad media fue de 28,75 (± 2,20), el 63,94 % (149) mujeres, la prevalencia general del SAP; 70,38 % (164/233), SAP en hombres 75 % (63/84) y mujeres 67,78 % (101/149) p=0,0014, los 2 primeros años con mayor frecuencia de SAP; 65 (85,52 %), 59 (86,76 %) repectivamente p=0,0009, de especialidades quirúrgicas 63 (90 %) p=0,0071. Las subescalas del MBI el AE;79,82 % (186) con un promedio de 35,39 (± 11,61) puntos. El PHEEM de los MR con SAP; 107,9(( 19,6) puntos y sin SAP; 136,3(( 12,1) puntos IC 95 % 18,1-25,0 p= 0,0001. El PHEEM predijo el AE con R2=0,619, PPS; B= -0,18 (±0,009) p=0,001, y la DESP; R2= 0,385, PPS; B= -0,001 (±0,004) p=0,009 siendo PSS predictor significativo con correlación inversa en ambas. Conclusión: existe relación inversa entre el clima educativo y el sindrome de agotamiento profesional en la población estudiada, con alta prevalencia de este en residentes hombres de especialidades quirúrgicas, siendo el soporte social del ambiente educativo hospitalario un predictor significativo para el desarrollo del sindrome de agotamiento profesional.

Abstract The objective of this research was to evaluate the quality of panels produced with different proportions of Pinus oocarpa wood particles and industrial cigarette waste. The wood came from an experimental field and the cigarette waste was obtained through a donation. The particles were mixed in different proportions (100% pine particles, 90% pine particles and 10% cigarette particles, 80% pine particles and 20% cigarette particles, 70% pine particles and 30% cigarette particles). The results showed that all particleboards reached the minimum value specified by NBR 14810-2 (ABNT, 2018) for Thickness Swelling (TS). All mechanical properties evaluated showed a reduction in values with the addition of cigarette residue particles and the values obtained did not meet the minimum specified by the standard used for the modulus of rupture and modulus of elasticity. Regarding internal adhesion, the panels for T3 and T4 treatments reached the minimum value required by Brazilian standards. The thermal resistance of the panels increased with the inclusion of cigarette residue particles, but the effect was low depending on R 2 . donation 100% 100 (100 90 10 80 20 70 30 particles. particles) 148102 14810 14810- ABNT, ABNT (ABNT 2018 TS. TS (TS) elasticity adhesion T standards (10 9 1 8 7 3 1481 201 (TS (1 148 ( 14

Resumo O objetivo desta pesquisa foi avaliar a qualidade de painéis produzidos com diferentes proporções de partículas de madeira de Pinus oocarpa e resíduos de cigarro industrializado. As partículas foram misturadas em diferentes proporções (100% de partículas de pinus, 90% de partículas de pinus e 10% de partículas de cigarro, 80% de partículas de pinus e 20% de partículas de cigarro, 70% de partículas de pinus e 30% de partículas de cigarro). Os resultados evidenciaram que todos os painéis aglomerados atingiram o valor mínimo especificado pela NBR 14810-2 (ABNT, 2018) para o Inchamento em Espessura (IE). Todas as propriedades mecânicas avaliadas evidenciaram redução nos valores com a adição das partículas de resíduos de cigarro e os valores obtidos não atenderam ao mínimo especificado pela norma utilizada para o módulo de ruptura e módulo de elasticidade. Em relação a ligação interna os painéis dos tratamentos T3 e T4 atingiram o valor mínimo requerido pela norma brasileira. A resistência térmica dos painéis aumentou com a inclusão das partículas de resíduos de cigarro, porém o efeito foi baixo em função do R2. industrializado 100% 100 (100 90 10 80 20 70 30 cigarro. . cigarro) 148102 14810 2 14810- ABNT, ABNT (ABNT 2018 IE. IE (IE) elasticidade T brasileira R2 R (10 9 1 8 7 3 1481 201 (IE (1 148 ( 14