ABSTRACT Purpose: This prospective, randomized, unmasked, clinical trial aimed to report the visual outcomes of cataract surgery on both eyes versus cataract surgery on one eye in Brazilian patients. Methods: This study included patients with bilateral cataracts and binocular visual acuity worse than or equal to 0.3 logarithm of the minimum angle of resolution. The patients were randomly assigned to undergo surgery on one (Control Group) or both eyes (one eye at a time; Intervention Group). Postoperatively, self-reported visual function using Catquest-9SF (primary outcome measure), binocular visual acuity, stereopsis, and ocular dominance (secondary outcome measures) were compared. Results: A total of 151 patients (77 and 148 eyes in the Control and Intervention Groups, respectively) completed the follow-up. Patients who underwent surgery on both eyes exhibited significantly better self-reported visual function (p=0.036) and stereopsis (p=0.026) than those who underwent surgery on one eye. Binocular visual acuity and ocular dominance did not affect the group comparisons. Conclusions: Surgery on both eyes resulted in significantly better self-reported visual function and stereopsis than surgery on one eye. Purpose prospective randomized unmasked Methods 03 0 3 0. resolution Group time Group. . Postoperatively selfreported self reported Catquest9SF CatquestSF Catquest 9SF SF primary measure, measure , measure) secondary measures compared Results 15 77 (7 14 Groups respectively followup. followup follow up. up follow-up p=0.036 p0036 p 036 (p=0.036 p=0.026 p0026 026 (p=0.026 comparisons Conclusions 1 7 ( p=0.03 p003 (p=0.03 p=0.02 p002 02 (p=0.02 p=0.0 p00 (p=0.0 p=0. p0 (p=0. p=0 (p=0 p= (p= (p

Abstract Building structures made of cast-in-place reinforced concrete use timber for formwork, struts, scaffolding, safety elements, and temporary construction site structures, which characterize the underutilization of biomaterial in a function of short life cycles and low added value. This work aims to survey timber consumption for temporary purposes in high-rise buildings with reinforced concrete structures cast in loco. Secondary data obtained through a systematic and exploratory review of national and international articles on timber use, reuse, and disposal was used. For studies with primary data for vertical housing buildings, timber consumption per constructed area ranged from 0.002 to 0.054 m³/m². For studies with secondary data and high-rise buildings for different uses, wood consumption ranged from 0.002 to 0.077 m 3 /m 2 . There was variability in the results of 33 times (average), explained by the methods of quantification, applications, and reuse of the material. castinplace place formwork struts scaffolding elements value highrise high rise loco used 0002 0 002 0.00 0054 054 0.05 m³m² mm m³ m² m³/m² uses 0077 077 0.07 average, average , (average) quantification applications material 000 00 0.0 005 05 m³m m³/m 007 07 (average 0.

Resumo Estruturas de edifícios em concreto armado moldado in loco utilizam madeira para fôrmas, escoras, andaimes, elementos de segurança e estruturas provisórias de canteiro, que caracterizam a subutilização do biomaterial em uma função de curto ciclo de vida e baixo valor agregado. O objetivo deste trabalho é levantar o consumo de madeira para fins provisórios em obras verticais com estrutura em concreto armado moldado in loco. Utilizou-se dados secundários obtidos por meio de uma revisão sistemática e exploratória de artigos nacionais e internacionais sobre uso, reuso e descarte da madeira. Para estudos com dados primários de edifícios habitacionais verticais o consumo de madeira por área construída foi de 0,002 a 0,054 m³/m². Para estudos com dados secundários e edifícios verticais de outros usos, o consumo de madeira foi de 0,002 a 0,077 m³/m². Houve variabilidade dos resultados de 33 vezes (média), explicada pelos métodos de quantificação, aplicações e reuso do material. fôrmas escoras andaimes canteiro agregado Utilizouse Utilizou se uso 0002 0 002 0,00 0054 054 0,05 m³m² mm m³ m² m m³/m² usos 0077 077 0,07 3 média, média , (média) quantificação material 000 00 0,0 005 05 m³m m³/m 007 07 (média 0,

Abstract I am interested in showing the role that the water carriers played in the functioning of the city of Oaxaca, their organization, their work and sociability spaces, as well as the control and regulation mechanisms that the government apparatus deployed over them. We can track their presence in the urban space from the consultation of primary sources, documents that lie in the Municipal Historical Archive of the City of Oaxaca and the General Archive of the State of Oaxaca, primarily; as well as the reading of secondary sources, preparing for this purpose a thematic cartography. However, their vital function in the cities and their presence in historical files has been scarcely addressed in Oaxacan historiography. Long before the modern network system was implemented in the city, the water carrier performed this task until well into the 20th century, which shows that, if the capital’s society demanded their service, the modernization of the water supply and distribution service was still out of reach; at the same time, it reveals that as long as the city maintained a considerable extension and number of inhabitants, the water carrier was able to render their valuable service.

Resumen Me interesa mostrar el papel que desempeñó el aguador en el funcionamiento de la ciudad de Oaxaca, su organización, sus espacios de trabajo y de sociabilidad, así como los mecanismos de control y regulación que el aparato gubernamental desplegó sobre ellos. Podemos rastrear su presencia en el espacio urbano a partir de la consulta de fuentes primarias, documentos que yacen en el Archivo Histórico Municipal de la Ciudad de Oaxaca y el Archivo General del Estado de Oaxaca, primordialmente; al igual que en la lectura de fuentes secundarias, elaborando para este propósito una cartografía temática. No obstante su vital función en las ciudades y su presencia en los legajos históricos, estos trabajadores han sido escasamente abordados en la historiografía oaxaqueña. Mucho tiempo antes de que el moderno sistema en red se implementara en la ciudad, el aguador cumplió esa labor hasta bien entrado el siglo XX, lo que demuestra que, si la sociedad capitalina demandaba su servicio, la modernización del servicio de abasto y distribución del agua era aún lejana; al mismo tiempo revela que mientras la ciudad mantuvo una extensión y un número de habitantes considerable, pudo brindar su valioso servicio.

Abstract Background: Clavicle fractures represent 2.5-4% of all fractures observed in emergency services. 80% occurs in the middle third. Treatment by plating requires a higher level of evidence. Objective: To compare the functional outcomes of mid-shaft clavicle fractures managed with superior plating compared to anteroinferior plating. Trial Design: A randomized, double-blind, parallel, superiority clinical trial. Patients and methods: Patients with fractures of the clavicles AO15B1 and AO15B2 were studied. Patients were randomized to be treated with either 3.5 mm superior or anteroinferior plating. A rehabilitation program was designed for both groups. The primary outcome measure was the Disability of Arm, Shoulder, and Hand (DASH) score; secondary outcomes included pain, union rate, and complication rates. Results: Twenty-eight patients were studied and were eligible for analysis. Significant differences were found in the function assessed with the DASH score at 30 days for the superior plating compared with anteroinferior (43.74 vs. 29.26, respectively, p = 0.027), 60 days (23.97 vs. 11.18, p = 0.021), and 90 days (9.52 vs. 3.5, p = 0.016). One loosening with superficial infection was found with superior plating. Conclusions: Using an anteroinferior reconstruction plate in diaphyseal fractures offers better functional results than the upper plate in patients with fractures of the middle third of the clavicle.

Resumen Antecedentes: Las fracturas de clavícula comprenden el 2.5-4% de todas las fracturas observadas en los servicios de emergencia. El 80% se presentan en el tercio medio. La posición de la placa como tratamiento requiere mayor nivel de evidencia. Objetivo: Comparar los resultados funcionales de las fracturas diafisarias de clavícula manejadas con placa superior versus placa anteroinferior. Método: Ensayo clínico aleatorizado, doble ciego, paralelo, de superioridad. Se estudiaron pacientes con fractura diafisaria de clavícula AO15B1 y AO15B2. Se manejaron con placa de reconstrucción de 3.5 mm colocada en forma superior o anteroinferior. Se diseñó un programa de rehabilitación para ambos grupos. El resultado primario fue medido con el cuestionario DASH y los resultados secundarios incluyeron dolor, presencia de consolidación y complicaciones. Resultados: Fueron elegibles para análisis 28 pacientes. Se encontraron diferencias significativas de la escala DASH a los 30 días para la maniobra superior comparada con la inferior (43.74 vs. 29.26, respectivamente; p = 0.027), a los 60 días (23.97 vs. 11.18; p = 0.021) y a los 90 días (9.52 vs. 3.5; p = 0.016). Conclusiones: El uso de placa de reconstrucción anteroinferior en las fracturas diafisarias ofrece mejores resultados funcionales en comparación con la placa superior en pacientes con fracturas de tercio medio de clavícula.

Abstract Introduction: The sea cucumber Holothuria (Halodeima) grisea Selenka, 1867 is a common echinoderm in intertidal regions along the Brazilian coast, which recently became the focus of unreported and unregulated fisheries. This study was carried out in sandy-rocky substrates at Armação do Itapocoroy, Penha, Santa Catarina (26o47’ S; 48o36’ W), near its southern limit of geographic distribution. Objective: To determine the densities (individuals*m-2) of Holothuria (H.) grisea within a spatial-temporal perspective as well as to determine biometric and growth characteristics of the population. Methods: Two-meter wide transects perpendicular to the coastline were carried out in winter and spring 2019 and in summer and spring 2020, in periods of spring low-tides. In each sampling occasion the total number of specimens of H. grisea were determined, and a group of 90 organisms was submitted to in situ biometrics (weight, length and width), and immediately returned alive to their habitat. Results: The densities of H. (H.) grisea were significantly higher in the subtidal sector and lower in the upper intertidal sector with no indication of significant differences among sampling campaigns. Depth was the primary factor explaining the observed density patterns and rugosity of the substrate was secondary but also important. The body length ranged from 5.2 to 22.5 cm, whereas the weight varied from 6.0 to 230 g. The mean and modal lengths were 12.54 and 13 cm, respectively. Approximately 75 % of the population sampled was between 10 and 14 cm and the average weight was 60 g. Estimates from von Bertalanffy growth function indicate that the youngest sea cucumber was one year-old, and the oldest had approximately two and a half years. Conclusions: This is the first study to determine biometric parameters for H. (H.) grisea in southern Brazil and the first one to estimate growth and age estimates for a wild population of this species. The densities recorded in the present study were lower than those previously reported for this region, suggesting anthropic influence.

Resumen Introducción: El pepino de mar Holothuria (Halodeima) grisea Selenka, 1867 es un equinodermo común en las regiones intermareales a lo largo de la costa brasileña, que recientemente se convirtió en foco de pesquerías no declaradas y no reguladas. Este estudio se realizó en sustratos arenosos-rocosos en Armação do Itapocoroy, Penha, Santa Catarina (26o47’ S; 48o36’ W), cerca del límite sur de su distribución geográfica. Objetivo: Determinar las densidades (individuos*m-2) de Holothuria (H.) grisea dentro de una perspectiva espacio-temporal así como determinar las características biométricas y de crecimiento de la población. Métodos: Se realizaron transectos de dos metros de ancho perpendiculares a la línea de costa en invierno y primavera de 2019 y en verano y primavera de 2020, en periodos de bajamar sicigia. En cada ocasión de muestreo se determinó el número total de especímenes de H. (H.) grisea, y se sometió un grupo de 90 organismos a biometría in situ (peso, longitud y ancho), e inmediatamente se los devolvieron vivos a su hábitat. Resultados: Las densidades de H. (H.) grisea fueron significativamente más altas en el sector submareal y más bajas en el sector intermareal superior sin indicios de diferencias significativas entre las campañas de muestreo. La profundidad fue el factor principal que explica los patrones de densidad observados y la rugosidad del sustrato fue secundaria pero también importante. La longitud del cuerpo varió de 5.2 a 22.5 cm, mientras que el peso varió de 6.0 a 230 g. Las longitudes media y modal fueron 12.54 y 13 cm, respectivamente. Aproximadamente el 75 % de la población muestreada midió entre 10 y 14 cm y el peso promedio fue de 60 g. Estimados de la función de crecimiento de von Bertalanffy indican que el ejemplar más joven presentaba un año de edad, mientras el más viejo presentaba cerca de dos años y medio. Conclusiones: Este es el primer estudio que determina parámetros biométricos para una población de H. (H.) grisea en el sur de Brasil y el primero en estimar el crecimiento y edades para una población salvaje de esta especie. Las densidades registradas en el presente estudio fueron inferiores a las reportadas previamente para esta región sugiriendo la ocurrencia de influencia antrópica.

Abstract 16. Measurement of arterial gases is a useful diagnostic tool for evaluating pulmonary function in terms of oxygen and carbon dioxide exchange between alveoli and blood capillaries. Therefore, it is essential for the management of dogs with respiratory dysfunction. The interpretation of arterial oxygen pressure and arterial carbon dioxide pressure allows the identification of oxygenation and ventilation failures. To estimate the mechanism underlying hypoxia and, therefore, the prognosis of the condition, the alveolar-arterial gradient should preferably be calculated before oxygen therapy. Meanwhile, to evaluate the degree of severity of pulmonary dysfunction in a patient subjected to inspired oxygen fractions higher than 21%, as well as the response to oxygen therapy, it is useful to monitor the PaO2/FiO2 ratio. SaO2/FiO2 and SpO2/FiO2 ratios are diagnostic resources that are currently being investigated as indicators of oxygenation failure, with promising preliminary results in dogs. This review aims to concisely present the current application of these indicators in evaluating pulmonary function in canines with primary or secondary respiratory tract pathologies.

Resumen 12. La medición de gases arteriales es una herramienta diagnóstica útil para evaluar la función pulmonar respecto del intercambio de oxígeno y dióxido de carbono entre alvéolos y capilares sanguíneos, por tanto, es fundamental en el abordaje del paciente canino con disfunción respiratoria. La interpretación de la presión arterial de oxígeno y la presión arterial de dióxido de carbono permiten la identificación de fallas en la oxigenación y ventilación. Para estimar el mecanismo que subyace a la hipoxia y por tanto el pronóstico de la condición, el gradiente alvéolo-arterial se debe calcular, preferiblemente previo a la terapia con oxígeno; mientras que para evaluar el grado de severidad de la disfunción pulmonar en un paciente sometido a fracciones inspiradas de oxígeno superiores a 21%, así como la respuesta a la oxigenoterapia, es útil monitorear el radio PaO2/FiO2. Los radios SaO2/FiO2 y SpO2/FiO2 son recursos diagnósticos que actualmente se están investigando como indicadores de falla en la oxigenación con resultados preliminares prometedores en caninos. Esta revisión pretende presentar de forma concisa, la aplicación actual de dichos indicadores en la evaluación de la función pulmonar en los caninos con patologías primarias o secundarias del tracto respiratorio.

ABSTRACT Introduction: There is no consensus on the impact of coronary artery disease in patients undergoing transcatheter aortic valve implantation. Therefore, the objective of this study was, in a single-center setting, to evaluate the five-year outcome of transcatheter aortic valve implantation patients with or without coronary artery disease. Methods: All transcatheter aortic valve implantation patients between 2009 and 2019 were included and grouped according to the presence or absence of coronary artery disease. The primary endpoint, five-year all-cause mortality, was evaluated using Cox regression adjusted for age, sex, procedure years, and comorbidities. Comorbidities interacting with coronary artery disease were evaluated with interaction tests. In-hospital complications was the secondary endpoint. Results: In total, 176 patients had aortic stenosis and concomitant coronary artery disease, while 170 patients had aortic stenosis only. Mean follow-up was 2.2±1.6 years. There was no difference in the adjusted five-year all-cause mortality between transcatheter aortic valve implantation patients with and without coronary artery disease (hazard ratio 1.00, 95% confidence interval 0.59-1.70, P=0.99). In coronary artery disease patients, impaired renal function, peripheral arterial disease, or ejection fraction < 50% showed a significant interaction effect with higher five-year all-cause mortality. No significant differences in complications between the groups were found. Conclusion: Five-year mortality did not differ between transcatheter aortic valve implantation patients with or without coronary artery disease. However, in patients with coronary artery disease and impaired renal function, peripheral arterial disease, or ejection fraction < 50%, we found significantly higher five-year all-cause mortality. Introduction Therefore singlecenter single center setting fiveyear five year Methods 200 201 endpoint allcause all cause age sex years comorbidities tests Inhospital hospital Results total 17 only followup follow up 2216 2 1 6 2.2±1. hazard 100 00 1.00 95 0.591.70, 059170 0.59 1.70, 0 59 70 0.59-1.70 P=0.99. P099 P P=0.99 . 99 P=0.99) function 50 Conclusion Fiveyear Five However 20 221 2.2±1 10 1.0 9 591 0.591.70 05917 059 0.5 1.70 5 7 0.59-1.7 P09 P=0.9 22 2.2± 1. 0.591.7 0591 05 0. 1.7 0.59-1. P0 P=0. 2.2 0.591. 0.59-1 P=0 2. 0.591 0.59- P=

ABSTRACT Introduction: Functional incapacity caused by physical alterations leads to significant limitations in daily activities and has a major impact on the return of people with disabilities to the social space and the workplace. This calls for an evaluation of the long-term influence of the use of a device specially developed for orthostatic posture on the physiological, biomechanical and functional parameters of amputees and spinal cord patients. Objective: The objective was evaluate the effect of postural support device use on function, pain, and biomechanical and cardiologic parameters in spinal cord injury and amputees patients compared to a control group. Methods: The orthostatic device was used by the participants for a period of ten consecutive days, for three cycles of 50 minutes each day, and a 15-day follow-up. Participants were positioned and stabilized using adjustable straps on the shoulders, trunk, and hips. The primary outcome was brief pain inventory. Fifteen participants were included the control group, 15 in the amputee group, and 15 in the spinal cord group. Results: Our results demonstrate that the use of the device allows the orthostatic position of amputees and spinal cord patients evaluated for ten days, leading to improved functionality and pain in the spinal cord and amputee groups compared to the control group. In addition, no changes were observed for secondary outcomes, indicating that the use of the device did not cause harm interference to patients. Conclusion: The long-term use of the orthostatic device is beneficial for improving functionality, reduce pain in amputees and spinal cord injury patients. Level of evidence II; Therapeutic Studies - Investigating the results of treatment. Introduction workplace longterm long term physiological Objective function group Methods days 5 day 15day followup. followup follow up. up follow-up shoulders trunk hips inventory 1 Results addition outcomes Conclusion II treatment

RESUMO Introdução: A incapacidade funcional causada por alterações físicas leva a limitações significativas nas atividades diárias e gera um grande impacto no retorno das pessoas com deficiência ao espaço social e ao local de trabalho, demandando a avaliação da influência em longo prazo do uso de um dispositivo especialmente desenvolvido para a postura ortostática nos parâmetros fisiológicos, biomecânicos e funcionais de pacientes amputados e com medula espinhal. Objetivo: O objetivo foi avaliar o efeito do uso do dispositivo de suporte postural na função, dor e parâmetros biomecânicos e cardiológicos em pacientes com lesão medular e amputados em comparação com um grupo controle. Métodos: O aparelho ortostático foi utilizado pelos participantes por um período de dez dias consecutivos, em três ciclos de 50 minutos diários, com acompanhamento de 15 dias. Os participantes foram posicionados e estabilizados por meio de alças ajustáveis nos ombros, tronco e quadris. O desfecho primário foi o questionário Breve Inventário de Dor. Quinze participantes foram incluídos no grupo controle, 15 no grupo amputado e 15 no grupo medular. Resultados: Nossos resultados demonstram que o uso do dispositivo permite a posição ortostática de amputados e pacientes com lesão medular avaliados por dez dias, levando a melhora da funcionalidade e dor nos grupos de amputados e medula espinhal em relação ao grupo controle. Além disso, não foram observadas alterações nos resultados secundários, indicando que o uso do dispositivo não causou interferência prejudicial aos pacientes. Conclusão: O uso prolongado do dispositivo ortostático é benéfico para melhorar a funcionalidade, reduzir a dor em amputados e pacientes com lesão medular. Nível de Evidência II; Estudos Terapêuticos - Investigação dos resultados de tratamento. Introdução trabalho fisiológicos Objetivo função controle Métodos consecutivos 5 diários 1 ombros quadris Dor Resultados disso secundários Conclusão II tratamento

ABSTRACT The evolution of woodpecker behaviors in association with their morphological adaptations is not well understood. This investigation aimed to determine the relationship between the anatomy of the jaw apparatus, the type of food consumed and the foraging mode of these birds. We present detailed anatomical descriptions of all parts of the jaw apparatus of true woodpeckers. Their characteristics were mapped into a consensus phylogenetic tree to describe woodpecker evolution. When morphological analyses were associated with feeding/foraging behavior, distinct patterns emerged. The protractor quadrati and pterygoideus systems are more developed in species that adopt pecking/hammering behaviors, even as secondary habits. By comparing Hemicircus (frugivorous with a poorly developed jaw apparatus) with the last common ancestor of Picinae, the early evolution of the jaw apparatus was found to be related to the type of food consumed. However, it became more complex in the ancestral lineage of Picinae, which enabled these birds to catch insects by gleaning/probing. It is hypothesized that the jaw apparatus of Picinae has evolved in response to foraging tactics and not to the type of food consumed. Pecking/hammering, as a secondary behavior, has evolved independently in Dryocopus, Celeus, and Dendropicus. Moreover, it has become more complex in Piculus and the clade comprising Blythipicus/Reinwardtipicus/Camphephilus, as they utilize pecking/hammering as their primary behavior. understood woodpeckers feedingforaging feeding behavior emerged peckinghammering pecking hammering habits frugivorous However gleaningprobing gleaning probing gleaning/probing Peckinghammering Pecking Pecking/hammering Dryocopus Celeus Dendropicus Moreover BlythipicusReinwardtipicusCamphephilus Blythipicus Reinwardtipicus Camphephilus Blythipicus/Reinwardtipicus/Camphephilus

In this article, we propose an analysis of twenty textbooks used in Physics education for undergraduate and graduate programs. The main objective is to investigate how these textbooks approach and justify the probabilistic interpretation of the square of the modulus of the wave function in Quantum Mechanics. From the perspective of physics education, the importance of teaching not only scientific concepts but also the underlying justification for these concepts is highlighted. Therefore, the discussion of the analysis of these works is based on primary and secondary sources related to the topic. The main questions to be addressed are what arguments and evidence are presented to legitimize the probabilistic interpretation associated with the wave function and what limitations are identified in each adopted didactic approach. article programs Mechanics highlighted Therefore topic

Neste artigo propomos uma análise de vinte livros didáticos utilizados no ensino de Física em cursos de licenciatura e bacharelado, com o objetivo de investigar como eles abordam e justificam a interpretação probabilística do quadrado do módulo da função de onda na Mecânica Quântica. Do ponto de vista do ensino de física, destaca-se a importância de ensinar não apenas os conceitos científicos, mas também as justificativas subjacentes a esses conceitos. Nesse sentido, a discussão da análise das obras busca amparo nas fontes primárias e secundárias que tratam sobre a temática. As principais questões a serem respondidas são quais argumentos e evidências são apresentados para legitimar a interpretação probabilística associada a função de onda e quais limitações são identificadas em cada abordagem didática adotada. bacharelado Quântica física destacase destaca se científicos sentido temática adotada

Abstract Introduction Deep interarytenoid groove (DIG) may cause swallowing dysfunction in children; however, the management of DIG has not been established. Objective We evaluated the subjective and objective outcomes of interarytenoid augmentation with injection in children with DIG. Methods Consecutive children under 18 years of age who underwent injection laryngoplasty for DIG were reviewed. Data pertaining to demographics, past medical history, past surgical history, and results of pre and postoperative video fluoroscopic swallow study (VFSS) were obtained. The primary outcome measure was the presence of thin liquid aspiration or penetration on postoperative VFSS. The secondary outcome measure was caregiver-reported improvement of symptoms. Results Twenty-seven patients had VFSS before and after interarytenoid augmentation with injection (IA). Twenty (70%) had thin liquid penetration and 12 (44%) had thin liquid aspiration before the IA. Thin liquid aspiration resolved in 9 children (45%) and persisted in 11 (55%). Of the 12 children who had thin liquid aspiration prior to IA, 6 (50%) had resolution of thin liquid aspiration after IA. Conclusions Injection laryngoplasty is a safe tool to improve swallowing function in children with DIG. Further studies are needed to assess the long-term outcomes of IA and identify predictors of successful IA in children with DIG. (DIG however established 1 reviewed demographics history (VFSS obtained caregiverreported caregiver reported symptoms Twentyseven seven . (IA) 70% 70 (70% 44% 44 (44% 45% 45 (45% 55%. 55 55% (55%) 50% 50 (50% longterm long term (IA 7 (70 4 (44 (45 5 (55% (50 (7 (4 (55 (5 (

ABSTRACT Objective: To evaluate the association of TSH, free T3 (FT3), free T4 (FT4), and conversion (FT3:FT4) ratio values with incident hypertension. Materials and methods: The study included data from participants of the ELSA-Brasil study without baseline hypertension. Serum TSH, FT4 and FT3 levels, and FT3:FT4 ratio values were assessed at baseline, and incident hypertension (defined by blood pressure levels ≥ 140/90 mmHg) was estimated over a median of 8.2 years of follow-up. The risk of incident hypertension was evaluated considering a 1-unit increase in TSH, FT4, FT3, and conversion ratio values and after dividing these variables into quintiles for further analysis using Poisson regression with robust variance. The results are presented as relative risks (RR) and 95% confidence intervals (CIs) before and after adjustment for multiple variables. Results: The primary analysis incorporated data from 5,915 euthyroid individuals, and the secondary analysis combined data from all euthyroid individuals, 587 individuals with subclinical hypothyroidism, and 31 individuals with subclinical hyperthyroidism. The rate of incident hypertension was 28% (95% CI: 27%-29.3%). The FT4 levels in the first quintile (0.18-1.06 ng/dL) were significantly associated with incident hypertension (RR: 1.03, 95% CI: 1.01-1.06) at follow-up. The association between FT4 levels in the first quintile and incident hypertension was also observed in the analysis of combined data from euthyroid individuals and participants with subclinical thyroid dysfunction (RR: 1.04, 95% CI: 1.01-1.07). The associations were predominantly observed with systolic blood pressure levels in euthyroid individuals. However, in the combined analysis incorporating euthyroid participants and individuals with subclinical thyroid dysfunction, the associations were more pronounced with diastolic blood pressure levels. Conclusion: Low FT4 levels may be a mild risk factor for incident hypertension in euthyroid individuals and persons with subclinical thyroid dysfunction. Objective TSH T FT , (FT3) (FT4) FT3FT4 FTFT (FT3:FT4 methods ELSABrasil ELSA Brasil FT3:FT defined 14090 140 90 140/9 mmHg 82 8 2 8. followup. followup follow up. up follow-up 1unit unit 1 variance RR (RR 95 CIs (CIs Results 5915 5 915 5,91 58 hypothyroidism 3 hyperthyroidism 28 (95 CI 27%29.3%. 27293 27% 29.3% . 27 29 27%-29.3%) 0.181.06 018106 0.18 1.06 0 18 06 (0.18-1.0 ng/dL ngdL ng dL 103 03 1.03 1.011.06 101106 1.01 01 1.01-1.06 104 04 1.04 1.011.07. 101107 1.07 07 1.01-1.07) However Conclusion (FT3 (FT4 FT3FT (FT3:FT 1409 14 9 140/ 591 91 5,9 (9 27%29.3% 2729 293 29.3 27%-29.3% 181 0.181.0 01810 018 0.1 106 1.0 (0.18-1. 10 011 1.011.0 10110 101 1.01-1.0 1.011.07 107 1.01-1.07 (FT 59 5, ( 27%29.3 272 29. 27%-29.3 0.181. 0181 0. 1. (0.18-1 1.011. 1011 1.01-1. 27%29. 27%-29. 0.181 (0.18- 1.011 1.01-1 27%29 27%-29 (0.18 1.01- 27%2 27%-2 (0.1 27%- (0. (0

RESUMEN El entrenamiento muscular del suelo pélvico (EMSP) se recomienda como tratamiento de primera línea para las pruebas de nivel 1 de incontinencia urinaria de esfuerzo (IUE). Actualmente, se utiliza la gimnasia abdominal hipopresiva (GAH) en la práctica clínica con este fin. Este estudio tuvo por objetivo comprobar la superioridad de un tratamiento experimental en comparación con el tratamiento de referencia para la IUE y la función del suelo pélvico en mujeres menopáusicas. Se realizó un ensayo clínico aleatorizado de no inferioridad con 31 mujeres climatéricas sexualmente activas y con IUE. Las participantes se distribuyeron en dos grupos: 16 se sometieron a EMSP y 15 a GAH. Ambos recibieron 26 sesiones, dos veces por semana, en sesiones individuales. Todas las voluntarias fueron evaluadas en dos momentos, al principio y al final de las intervenciones. El resultado primario se evaluó mediante el cuestionario ICIQ-SF, y el resultado secundario mediante la evaluación bidigital del suelo pélvico. Para el análisis estadístico se utilizó la prueba ANOVA de dos vías, seguida de la prueba posterior de Tukey cuando necesario. El EMSP tuvo un mejor resultado en la mejora de la IUE (p=0,01). No hubo diferencias entre los grupos en cuanto a la fuerza de contracción, el tiempo de mantenimiento y las repeticiones rápidas y lentas. En cuanto a la mejora de los síntomas de IUE, se concluyó que el EMSP es superior a la GAH. (EMSP . (IUE) Actualmente GAH (GAH fin menopáusicas 3 2 semana individuales momentos intervenciones ICIQSF, ICIQSF ICIQ SF, SF ICIQ-SF vías necesario p=0,01. p001 p p=0,01 0 01 (p=0,01) contracción lentas (IUE p00 p=0,0 (p=0,01 p0 p=0, (p=0,0 p=0 (p=0, p= (p=0 (p= (p

ABSTRACT Pelvic floor muscle training (PFMT) is recommended as first-line treatment for stress urinary incontinence (SUI) in women (scientific evidence level 1). Currently, hypopressive abdominal gymnastics (HAG) has been used in clinical practice without evidence for this purpose. To verify the superiority of an experimental treatment in relation to a positive control (gold standard) for the treatment of SUI and PFM function in climacteric women. A non-inferiority clinical trial was conducted with 31 climacteric women with SUI who were sexually active. They were allocated into two groups: 16 in the PFMT group and 15 in the HAG group. Both groups received 26 sessions twice per week and individual care. All participants were assessed twice, at the beginning and at the end of interventions. The primary outcome was assessed using the International Consultation on Incontinence Questionnaire - Short Form (ICIQ-SF) and the secondary were given by PFM function assessed via bidigital palpation. The methods used to analyze the results were the two-way repeated measures analysis of variance (ANOVA), followed by the Tukey post-hoc test, when necessary. PFMT was better in improving SUI in the primary outcome (p=0.01). The groups showed no significant difference in force of contraction, time of sustained PFM, and fast and slow repetitions at the time of analysis. Regarding the symptoms of SUI, PFMT performed better than HAG. (PFMT firstline first line (SUI scientific 1. 1 . 1) Currently (HAG purpose gold standard noninferiority non inferiority 3 active 2 care interventions ICIQSF ICIQ SF (ICIQ-SF palpation twoway way ANOVA, ANOVA , (ANOVA) posthoc post hoc test necessary p=0.01. p001 p p=0.01 0 01 (p=0.01) contraction (ANOVA p00 p=0.0 (p=0.01 p0 p=0. (p=0.0 p=0 (p=0. p= (p=0 (p= (p

RESUMO O treinamento dos músculos do assoalho pélvico (TMAP) é recomendado como primeira linha no tratamento do nível 1 de evidência da incontinência urinária de esforço (IUE). Atualmente, a Ginástica Abdominal Hipopressiva (GAH) tem sido utilizada na prática clínica com este propósito. Este estudo tem como objetivo verificar a superioridade de um tratamento experimental em relação ao tratamento padrão-ouro para IUE e função do assoalho pélvico em mulheres na menopausa. Foi conduzido um ensaio clínico randomizado de não inferioridade com 31 mulheres climatéricas, sexualmente ativas e com IUE. Elas foram alocadas em dois grupos, em que: 16 foram submetidas ao TMAP e 15 à GAH. Ambos receberam 26 sessões, duas vezes por semana, em atendimentos individuais. Todas as voluntárias foram avaliadas em dois momentos, no início e ao término das intervenções. O desfecho primário foi avaliado pelo Questionário (ICIQ-SF) e o secundário pela avaliação bidigital do assoalho pélvico. Para a análise estatística, foram utilizados o teste ANOVA de duas vias, seguido do pós-teste de Tukey, quando necessário. O TMAP foi superior na melhora da IUE (p=0.01). Não houve diferença entre os grupos em relação a força de contração, tempo de sustentação, repetições rápidas e lentas. Em relação à melhora dos sintomas de IUE, concluiu-se que o TMAP é superior a GAH. (TMAP . (IUE) Atualmente GAH (GAH propósito padrãoouro padrão ouro menopausa 3 climatéricas 2 sessões semana individuais momentos intervenções ICIQSF ICIQ SF (ICIQ-SF estatística vias pósteste pós Tukey necessário p=0.01. p001 p p=0.01 0 01 (p=0.01) contração sustentação lentas concluiuse concluiu se (IUE p00 p=0.0 (p=0.01 p0 p=0. (p=0.0 p=0 (p=0. p= (p=0 (p= (p

RESUMO Fundamento: As evidências acerca das sequelas a longo prazo após internação por síndrome do desconforto respiratório agudo por COVID-19 ainda são escassas. Objetivo: Avaliar alterações nas funções pulmonar, cardíaca e renal e na qualidade de vida após internação por síndrome do desconforto respiratório agudo secundária à COVID-19. Métodos: Trata-se de estudo multicêntrico, caso-controle, incluindo 220 participantes. Os casos serão definidos como pacientes hospitalizados por síndrome do desconforto respiratório agudo devido à COVID-19. No Grupo Controle, serão selecionados indivíduos sem histórico de hospitalização nos últimos 12 meses ou sintomas a longo prazo de COVID-19. Todos os indivíduos serão submetidos à espirometria pulmonar com teste de difusão pelo monóxido de carbono, tomografia de tórax, ressonância magnética cardíaca e renal com gadolínio, ergoespirometria, creatinina sérica e urinária, proteínas totais e microalbuminúria urinária, além de questionários de qualidade de vida. Os casos serão avaliados 12 meses após a alta hospitalar e os controles, 90 dias após a inclusão no estudo. Para todas as análises estatísticas, será assumido como significativo o valor p < 0,05. Resultados: O desfecho primário do estudo foi definido com a capacidade de difusão pulmonar aferida para o monóxido de carbono a partir de 12 meses. Os demais parâmetros das funções pulmonar, cardíacas e renal e da qualidade de vida foram definidos como desfechos secundários. Conclusão: Este estudo visa determinar as sequelas a longo prazo nas funções pulmonar, cardíaca e renal e na qualidade de vida de pacientes internados por síndrome do desconforto respiratório agudo devido à COVID-19 na população brasileira. Fundamento COVID19 COVID 19 COVID-1 escassas Objetivo COVID19. 19. Métodos Tratase Trata se multicêntrico casocontrole, casocontrole caso controle, controle caso-controle 22 participantes Controle 1 tórax gadolínio ergoespirometria urinária controles 9 estatísticas 005 0 05 0,05 Resultados secundários Conclusão brasileira COVID1 COVID- 2 00 0,0 0,

ABSTRACT Rationale: Evidence about long-term sequelae after hospitalization for acute respiratory distress syndrome due to COVID-19 is still scarce. Purpose: To evaluate changes in pulmonary, cardiac, and renal function and in quality of life after hospitalization for acute respiratory distress syndrome secondary to COVID-19. Methods: This will be a multicenter case–control study of 220 participants. Eligible are patients who are hospitalized for acute respiratory distress syndrome due to COVID-19. In the control group, individuals with no history of hospitalization in the last 12 months or long-term symptoms of COVID-19 will be selected. All individuals will be subjected to pulmonary spirometry with a carbon monoxide diffusion test, chest tomography, cardiac and renal magnetic resonance imaging with gadolinium, ergospirometry, serum and urinary creatinine, total protein, and urinary microalbuminuria, in addition to quality-of-life questionnaires. Patients will be evaluated 12 months after hospital discharge, and controls will be evaluated within 90 days of inclusion in the study. For all the statistical analyses, p < 0.05 is the threshold for significance. Results: The primary outcome of the study will be the pulmonary diffusing capacity for carbon monoxide measured after 12 months. The other parameters of pulmonary, cardiac, and renal function and quality of life are secondary outcomes. Conclusion: This study aims to determine the long-term sequelae of pulmonary, cardiac, and renal function and the quality of life of patients hospitalized for acute respiratory distress syndrome due to COVID-19 in the Brazilian population. Rationale longterm long term COVID19 COVID 19 COVID-1 scarce Purpose COVID19. 19. Methods casecontrol case 22 participants group 1 selected test tomography gadolinium ergospirometry creatinine protein microalbuminuria qualityoflife questionnaires discharge 9 analyses 005 0 05 0.0 significance Results outcomes Conclusion population COVID1 COVID- 2 00 0.

Ethiopia has extensive experience with traditional dispute resolution practices that function parallel to the formal courts in various parts of the country. In pluralistic justice systems where state and non-state justice systems operate, how the state responds to the situation is significant. Through a study of cases prosecuted by the Jaarsa Biyyaa institution of the Arsi Oromo people, this article explores whether and how traditional dispute resolution institutions (TDRIs) interact with the formal courts and the impact of this interaction, if any, on the culture of the Arsi Oromo people. In line with that, the article analyses primary data gathered through two months of ethnographic fieldwork in Negele Arsi town in Ethiopia and from secondary sources of previous scholarly works. The findings show a shared interest in jurisdiction (predominantly over criminal matters) and competition between the Jaarsa Biyyaa and the formal courts. Moreover, there is also a practice of cooperation and complementarity between the Jaarsa Biyyaa and the formal justice system (FJS) where each recognises the other in practice. For the Arsi Oromo people, such mutual recognition is an opportunity to maintain the clanship organisation. More importantly, mutual recognition promotes conflict management in the community, which serves as a valuable lesson for the country. Other than the opportunities that arise, there are constraints such as the interruption of Jaarsummaa (elders reconciliation), broken social bonds and enmity.