Resumen: Las AgNPs se están utilizando ampliamente debido a sus excelentes propiedades antimicrobianas que les permiten ser incorporadas en diversas áreas de la odontología, como materiales dentales, ortodoncia, endodoncia, periodoncia y prostodoncia, entre otras. El objetivo de este trabajo fue revisar el uso de las AgNPs en las diferentes áreas de la odontología y las innovaciones tecnológicas asociadas. Se realizaron búsquedas sistemáticas en las bases de datos EBSCOhost y PubMed, con las palabras clave: “AgNPs” o “silver nanoparticles”, “dentistry” o “dentist” o “dental”, “materials” en un periodo que va del 2012 al 2023, en idioma inglés. Se encontraron un total de 261 artículos, se eliminaron los artículos repetidos, artículos de revisión, o artículos que no pertenecían al área dental. Se incluyeron en la revisión 116 artículos que cumplían los criterios establecidos; se puede observar que la mayoría de las investigaciones son estudios in vitro y una pequeña parte son investigaciones clínicas o realizadas en animales, la mayoría de las investigaciones muestran resultados positivos e innovadores para el uso de las AgNPs. Los estudios muestran una óptima actividad antibacteriana de las AgNPs cuando estas se combinan con materiales dentales como enjuagues, soluciones irrigantes, cementos, resinas, adhesivos, recubrimientos de metales, soluciones antisépticas, apósitos quirúrgicos, por mencionar algunos. La literatura revisada muestra un prometedor futuro para las AgNPs, pues no solo tienen actividad antibacteriana frente a las principales bacterias orales aerobias y anaerobias Gram positivas y Gram negativas, sino también un efecto antifúngico y propiedades antinflamatorias, sin comprometer las propiedades de la mayoría de los materiales a los cuales son incorporadas. Sin embargo, su uso sigue siendo controvertido debido a que estos nanomateriales pertenecen a una nueva clase de material; el progreso en esta nueva disciplina (la nanotoxicología) depende de encontrar metodologías que permitan evaluar la toxicidad en estados químicos, estudios in vitro y clínicos.

Abstract: AgNPs are being widely used due to their excellent antimicrobial properties that allow them to be incorporated in various areas of dentistry ranging from dental materials, orthodontics, endodontics, periodontics and prosthodontics among others. The objective of this work was to review the use of AgNPs in different areas of dentistry and the associated technological innovations. Systematic searches were performed in the EBSCOhost and PubMed databases, with the keywords: “AgNPs” or “silver nanoparticles”, “dentistry” or “dentist” or “dental”, and “materials” in a period from 2012 to 2023 in the English language. A total of 261 articles were found, repeated articles, review articles, and articles that did not belong to the dental area were eliminated. A total of 116 articles that met the criteria were included in the review, it can be observed that most of the research is in vitro studies and a small part is clinical research or conducted on animals, most of the research show positive and innovative results for the use of AgNPs. The studies show an optimal antibacterial activity of AgNPs when they are combined with dental materials such as rinses, irrigant solutions, cements, resins, adhesives, metal coatings, antiseptic solutions, surgical dressings, among others. The literature reviewed shows a promising future for AgNPs since they not only have antibacterial activity against the main aerobic and anaerobic Gram positive and Gram-negative oral bacteria but also antifungal effect and anti-inflammatory properties, without compromising the properties of most of the materials in which they are incorporated. However, their use remains controversial because these nanomaterials belong to a new class of material; progress in this new discipline (nanotoxicology) depends on finding methodologies that allow the evaluation of toxicity in chemical states, in vitro and clinical studies.

Resumen Objetivo La gingivitis espongiótica es una patología benigna poco común y una entidad clínica patológica poco frecuente que los odontólogos pueden observar durante la atención odontológica. Es importante conocer la misma para poder diagnosticarla adecuadamente, describir sus características clínicas y elaborar un plan para su tratamiento. El objetivo de este artículo es presentar un caso clínico de esta patología poco conocida, describir sus características y su manejo clínico. Caso clínico Un niño de 7 años que ingresó derivado por su odontólogo a la cátedra de Estomatología de la Facultad de Odontología de la Universidad Nacional de Córdoba, Argentina, presentaba en la encía libre e insertada del maxilar superior una lesión con ausencia de sintomatología y evolución crónica, benigna y con cambios estéticos notorios. Se deriva a la cátedra de Periodoncia para realizar un tratamiento interdisciplinario. Tuvo una respuesta favorable al tratamiento de la lesión, y se realizó un seguimiento periódico de la misma evitando la técnica quirúrgica convencional para su tratamiento.

Abstract Aim Spongiotic gingivitis is a rare benign pathology and a rare clinical pathological entity that dentists can observe during dental care. It is important to know it to be able to properly diagnose it, describe its clinical characteristics and develop a plan for its treatment. The aim of this article is to present a clinical case of this little-known pathology and describe its characteristics as well as its clinical management. Clinical case A 7-yeard-old child who was referred by his dentist to the Department of Stomatology of the Faculty of Dentistry of the National University of Córdoba, Argentina, presented a lesion in the free and inserted gingiva of the upper jaw, with absence of symptoms and chronic, benign evolution with notable aesthetic changes. He is referred to the Periodontics department to perform interdisciplinary treatment. He had a favorable response to the treatment of the lesion, and a periodic follow-up was carried out, avoiding the conventional surgical technique for its treatment.

RESUMO Objetivo: Avaliar a eficácia da forma membranosa de fibrina rica em plaquetas associada ao retalho coronariamente avançado em pacientes atendidos na consulta de periodontia da Faculdade de Estomatologia de Villa Clara. Materiais e métodos: Foi realizado um estudo longitudinal na Faculdade de Estomatologia, Villa Clara, Santa Clara, Cuba, de janeiro de 2016 a março de 2017. A amostra foi composta por 17 indivíduos selecionados por meio de um método de amostragem intencional e não probabilístico. O procedimento tradicional de retalho coronariamente avançado foi aplicado aos dentes com recessão periodontal neste grupo. Além disso, foi colocada uma membrana de fibrina rica em plaquetas, derivada de sangue autólogo e preparada no Serviço de Medicina Regenerativa da mesma instituição, sob o retalho. O estudo analisou as seguintes variáveis: idade, sexo, comprimento da recessão, classificação de Miller, cobertura radicular, largura e ganho da gengiva inserida, categorias de avaliação e eficácia terapêutica. Resultados: A porcentagem de cobertura radicular foi maior na classe I e aumentou ao longo do tempo em todas as classes de Miller. A largura da gengiva inserida e o ganho aumentaram de um mês a um ano. A eficácia percentual foi de 93,18%. Conclusões: A terapia de recessão periodontal, com a forma membranosa de fibrina rica em plaquetas associada ao retalho coronariamente avançado, foi considerada eficaz em pacientes atendidos na consulta de periodontia da Faculdade de Estomatologia de Villa Clara.

ABSTRACT Objective: To evaluate the efficacy of the membranous form of platelet-rich fibrin associated with the coronally advanced flap in patients attended by consultation in periodontics at the Faculty of Stomatology of Villa Clara. Materials and methods: A longitudinal study was conducted at the Faculty of Stomatology, Villa Clara, Santa Clara, Cuba, from January 2016 to March 2017. The sample comprised 17 individuals selected using a purposive, non-probabilistic sampling method. The traditional coronally advanced flap procedure was applied to teeth with periodontal recession in this cohort. Additionally, a platelet-rich fibrin membrane, derived from autologous blood and prepared in the Regenerative Medicine Service of the same institution, was placed beneath the flap. The study analyzed the following variables: age, sex, recession length, Miller classification, root coverage, width and gain of inserted gingiva, evaluation categories, and therapeutic efficacy. Results: Root coverage percentage was higher in class I and increased over time in all Miller classes. Inserted gingival width and gain increased from one month to one year. The percentage efficacy was 93.18 %. Conclusions: Periodontal recession therapy, with the membranous form of platelet-rich fibrin associated with the coronally advanced flap, was considered effective in patients attended by consultation in periodontics at the Faculty of Stomatology of Villa Clara.

RESUMEN Objetivo: Evaluar la eficacia de la fibrina rica en plaquetas en su forma membranosa asociada al colgajo avanzado coronalmente en pacientes atendidos por consulta en periodoncia de la Facultad de Estomatología de Villa Clara. Materiales y métodos: Se realizó un estudio longitudinal en la Facultad de Estomatología de Villa Clara, Santa Clara, Cuba, de enero de 2016 a marzo de 2017. Se trabajó con una muestra de 17 personas seleccionadas de forma no probabilística intencional. A estas se les realizó el procedimiento tradicional de colgajo avanzado coronalmente en los dientes con recesión periodontal. Debajo de dicho colgajo, se colocó una membrana de fibrina rica en plaquetas, confeccionada a partir de sangre autóloga y elaborada en el Servicio de Medicina Regenerativa de la misma institución. Se analizaron las variables edad, sexo, largo de la recesión, clasificación de Miller, cobertura radicular, ancho y ganancia de encía insertada, categorías de evaluación y eficacia de la terapéutica. Resultados: El porcentaje de cobertura radicular fue superior en la clase I y se incrementó a lo largo del tiempo en todas las clases de Miller. El ancho y la ganancia de la encía insertada aumentaron del mes hasta el año. El porcentaje de eficacia fue de 93,18 %. Conclusiones: La terapéutica de la recesión periodontal, con la forma membranosa de fibrina rica en plaquetas asociada al colgajo avanzado coronalmente, se consideró eficaz en los pacientes atendidos en la consulta de periodoncia de la Facultad de Estomatología de Villa Clara.

Resumen Los vidrios bioactivos (VBa) son materiales biocerámicos que tienen una extensa aplicación en medicina y odontología. A causa de su contenido de calcio y fosfato son muy similares a la hidroxiapatita del tejido óseo. Su biocompatibilidad y bioactividad los hacen materiales muy útiles para ser aplicados en diferentes áreas de la práctica dental, tales como periodoncia, cirugía, odontología restauradora y endodoncia. En endodoncia los VBa están indicados para realizar protecciones pulpares directas, pulpotomías, desinfecciones y obturaciones del sistema de conductos radiculares. El objetivo del presente trabajo fue realizar una revisión de las propiedades biológicas de los VBa en relación a sus aplicaciones en endodoncia.

Abstract Abstract Bioactive glasses (BGs) are bioceramic materials with extensive clinical applications in medicine and dentistry. Because of their phosphate and calcium contents, they are like the hydroxyapatiteof bone tissue. Their biocompatibility and bioactivity make them very useful biomaterials in different areas of dental practice, such as periodontics, oral surgery, restorative dentistry, and endodontics. In endodontics, bioactive glasses are indicated for direct pulp capping, pulpotomies, disinfections and fillings of the root canal system. The aim of this work was to carry out a review of the biological properties of BGs in relation to its application in endodontics.

ABSTRACT: Anchoring is the process that allows new information to be inserted into the framework of pre-existing schemes. Allows to instrumentalize the content in communication. In During the training of specialists, we anchor contents with a situational diagnosis. The purpose of this essay was to anchor contents of mastication and mandibular dynamics in professionals, students in the specialization program in Periodontics, of the Faculty of Dentistry, Universidad de Chile. The program has a rehabilitation unit in reduced periodontium (one credit, 5 sessions). This is taught with situational diagnosis and active methodologies: Reverse classroom and small group discussion. The chewing and mandibular dynamics contents were anchored through these methodologies with videos, to stimulate the identification of patterns; pinned content is identified. Individual and collective reflection was encouraged and students from the 2020 (telematic) and 2022 (in-person) classes were compared. Students were coded from 1 to 14. Characterization of the 2020 cohort: 4 men, 4 women; 5.75 years of average graduation, 2 from U. del Desarrollo, 1 U. de Concepción, 2 U. de Talca, 2 U. de Chile and 1 U. de Los Andes. Cohort characterization 2022: 3 women, 3 men; 6 years of average graduation, 5 U. de Chile and 1 U. de La Frontera. The 2020 cohort identified patterns in the second session, except for students 5 and 7 who did so in the fifth session. During the collective reflection, transformational leadership predominated. Of the 2022 cohort, only student 14, was able to identify patterns in the second session, while all of her classmates did so in the fifth session. During the collective reflection, transactional leadership predominated. In teaching professionals, the same methodologies, applied telematically or in person to anchor new content, were influenced by the leadership styles of the students, which favored or delayed the identification of the patterns.

RESUMEN: El anclaje es el proceso que permite insertar lo nuevo en el entramado de esquemas preexistentes. Posibilita instrumentalizar el contenido en la comunicación. En formación de especialistas, anclamos contenidos con un diagnóstico situacional. El propósito de este ensayo fue, anclar contenidos de masticación y dinámica mandibular en profesionales, estudiantes del programa de especialización en Periodoncia, Facultad de Odontología, Universidad de Chile. El programa posee la unidad de rehabilitación en periodonto reducido (un crédito, 5 sesiones). Esta se imparte con diagnóstico situacional y metodologías activas: aula reversa y discusión de grupo pequeño. Los contenidos masticación y dinámicamandibular se anclaron mediante estas metodologías con videos, para estimular la identificación de patrones; contenido anclado es identificado. Se incentivó la reflexión individual y colectiva y se compararon los estudiantes de las promociones 2020 (telemática) y 2022 (presencial). Los estudiantes fueron codificados del 1 al 14. Caracterización de la cohorte 2020: 4 hombres, 4 mujeres; 5.75 años de egreso promedio, 2 U. Desarrollo, 1 U. de Concepción, 2 U. de Talca, 2 U. de Chile y 1 U de los Andes. Caracterización cohorte 2022: 3 mujeres, 3 hombres; 6 años de egreso promedio, 5 U. de Chile y 1 U. de La Frontera. La cohorte 2020 identificó patrones en la segunda sesión, a excepción de los estudiantes 5 y 7 que lo hicieron en la quinta sesión. Durante la reflexión colectiva, predominaron liderazgos transformacionales. De la cohorte 2022, solo el estudiante 14 identificó patrones en la segunda sesión y todos sus compañeros lo hicieron en la quinta sesión. Durante la reflexión colectiva, predominaron liderazgos transaccionales. En educación de profesionales, iguales metodologías, aplicadas telemáticamente o de manera presencial para anclar nuevos contenidos, se vieron influenciadas por los estilos de liderazgos de los estudiantes, que favorecieron o retardaron la identificación de patrones.

ABSTRACT Introduction: Retention of the upper canines is one of the most frequent orthodontic-surgical problems, with a high incidence in the general population. Objective: To characterize a patient with bilateral retention of the upper canines. Case report: A 13-year-old school patient was treated in the Maxillofacial Surgery Service at Manuel Ascunce Domenech University Hospital in Camagüey, in 2018. An interdisciplinary consultation was conducted with Comprehensive General Stomatology, Periodontics and Orthodontics, as well as a clinical study (interrogation and physical examination). The clinical absence of the crown of the upper canines 13 and 23 was observed. This was confirmed with a panoramic radiographic view. A surgical procedure was followed, with the discovery of the crowns of the canines and the elimination of the bone obstacle that prevented the eruption of these dental organs. Subsequently, brackets and wire traction were placed to mobilize the retained canines towards their normal position in the dental arch. Conclusions: Bilateral retention of the upper canines is rare in the child population that attends dental services. Its close association with oligodontia or absence of lateral incisors in its etiopathogenesis was evident. The orthodontic-surgical variant was the most appropriate treatment method for this case.

RESUMEN Introducción: La retención de los caninos superiores es uno de los problemas ortodóncico-quirúrgicos más frecuentes, con una elevada incidencia en la población general. Objetivo: Caracterizar a una paciente con retención bilateral de los caninos superiores. Presentación del caso: Una paciente escolar de trece años fue atendida en el Servicio de Cirugía Maxilofacial del Hospital Universitario “Manuel Ascunce Domenech” de Camagüey, en 2018. Se le realizó una consulta interdisciplinaria con Estomatología General Integral, Periodoncia y Ortodoncia, así como un estudio clínico (interrogatorio y examen físico). Se observó la ausencia clínica de la corona de los caninos superiores 13 y 23; esto se constató con una vista radiográfica panorámica. Se siguió una conducta quirúrgica, con el descubrimiento de las coronas de los caninos y la eliminación del obstáculo óseo que impedía la erupción de estos órganos dentarios. Posteriormente, se colocaron brackets y tracción alámbrica para movilizar los caninos retenidos hacia su posición normal en la arcada dentaria. Conclusiones: La retención bilateral de los caninos superiores es poco frecuente en la población infantil que acude a los servicios estomatológicos. Se evidenció su estrecha asociación con la oligodoncia o ausencia de los incisivos laterales en su etiopatogenia. La variante ortodóncica-quirúrgica fue el método de tratamiento más adecuado para este caso.

RESUMEN Las enfermedades periodontales son consideradas entre las más comunes entre las patologías bucales. Su frecuencia es cada vez más elevada en la población y existen varias patologías sistémicas y hábitos que empeoran su cuadro clínico. El objetivo de este trabajo fue determinar la frecuencia y características clínicas de pacientes con enfermedades periodontales que acuden a la cátedra de periodoncia en la Universidad Autónoma de Asunción en el período de 2011 al 2019. Estudio Observacional, descriptivo, retrospectivo, se procesaron 477 fichas clínicas de pacientes de la cátedra de Periodoncia de la Universidad Autónoma de Asunción desde el año 2011 al 2019. El tipo de muestreo utilizado fue no probabilístico por conveniencia. De las 477 fichas solo se analizaron 317 pacientes que cumplieron con los criterios de inclusión. Fueron el 56.46 % de sexo femenino y 43,53 % de sexo masculino, la mediana de edad fue de 33 (23-48) años. El 53% los pacientes presentaban periodontitis crónica y comorbilidades como diabetes e hipertensión arterial. Solo el 11,9 % fueron fumadores. En cuanto a los pacientes diabéticos la mayoría eran de sexo femenino y de edad avanzada, presentando como diagnóstico más frecuente la periodontitis crónica. El diagnóstico clínico más frecuente de la población estudiada fue la periodontitis crónica, seguido por la gingivitis.

ABSTRACT Periodontal diseases are considered among the most common among oral pathologies. Its frequency is increasingly higher in the population and there are several systemic pathologies and habits that worsen its clinical condition. The objective of this work was to determine the frequency and clinical characteristics of patients with periodontal diseases who attend the periodontics department at the Autonomous University of Asunción in the period from 2011 to 2019. Observational, descriptive, retrospective study, 477 clinical records were processed. of patients from the Department of Periodontics at the Autonomous University of Asunción from 2011 to 2019. The type of sampling used was non-probabilistic for convenience. Of the 477 records, only 317 patients who met the inclusion criteria were analyzed. They were 56.46% female and 43.53% male, the median age was 33 (23-48) years. 53% of the patients had chronic periodontitis and comorbidities such as diabetes and high blood pressure. Only 11.9% were smokers. Regarding diabetic patients, the majority were female and elderly, with chronic periodontitis as the most frequent diagnosis. The most frequent clinical diagnosis of the studied population was chronic periodontitis, followed by gingivitis.

ABSTRACT Introduction: The subject of Periodontics plays an important role in the curriculum of the Stomatology degree. Its approach addresses the process of periodontal health-sickness from a comprehensive perspective, which strengthens the formation of the basic general dentist. Objective: To critically evaluate the program of the subject Periodontics of the Stomatology degree, Plan E, to contribute to its improvement. Methods: The documental review of the main integrative discipline (General Stomatology) and the program of the subject Periodontics of the Plan E, of the Stomatology degree was used as an empirical level method. Results: The insufficiencies of the program were identified, its improvement was proposed and recommendations were made for its future transformation, considering the exit profile of the graduated of the Stomatology degree. Conclusion: The program of the subject adjusts in its objectives, content and evaluation, according to the model of the professional that is aspired to create, however, it is susceptible to be improved.

RESUMEN Introducción: La asignatura Periodoncia juega un papel fundamental en el plan de estudio de la carrera de Estomatología. Su enfoque aborda el proceso de salud-enfermedad periodontal desde una perspectiva integral, lo cual fortalece la formación del estomatólogo general básico. Objetivo: Evaluar de forma crítica el programa de la asignatura Periodoncia de la carrera de Estomatología, del Plan E, para contribuir a su perfeccionamiento. Métodos: Se empleó como método de nivel empírico la revisión documental de la disciplina principal integradora (Estomatología General) y del programa de la asignatura Periodoncia del Plan de Estudios E, de la carrera de Estomatología. Resultados: Se identificaron las insuficiencias del programa, se propuso su perfeccionamiento y se hicieron recomendaciones para su transformación futura, al considerar el perfil de salida del egresado de la carrera de Estomatología. Conclusiones: El programa de la asignatura se ajusta en sus objetivos, contenidos y evaluación, de acuerdo con el modelo del profesional que se aspira a formar; sin embargo, es susceptible de ser perfeccionado.

RESUMEN Introducción: La asociación del colgajo de reposición coronal, con el injerto de tejido conectivo subepitelial, constituye una modalidad de tratamiento empleada para la cobertura radicular que permite aumentar las indicaciones de este procedimiento e incrementa la estabilidad de los resultados en el tiempo. Objetivo: Evaluar los resultados del tratamiento de la recesión periodontal, con la utilización del colgajo de reposición coronal asociado a tejido conectivo subepitelial, cinco años después. Métodos: Se realizó una investigación descriptiva longitudinal, en pacientes con cinco años de operados, desde enero del 2020 a octubre del 2021, en la Facultad de Estomatología de la Universidad de Ciencias Médicas de Villa Clara. La población estuvo constituida por los pacientes operados con la técnica del colgajo de reposición coronal asociada a tejido conectivo subepitelial, desde marzo del 2014 a diciembre del 2016. Se utilizaron dos unidades de análisis: pacientes y dientes con recesión periodontal. Las variables utilizadas fueron: edad, sexo, clase de Miller, largo y cobertura de la recesión, ganancia de encía insertada, apariencia estética, categorías de evaluación. Resultados: El porcentaje de cobertura radicular a los cinco años tuvo una ligera disminución que no fue estadísticamente significativa para las clases I y II de Miller (p>0.05). El ancho de la encía insertada mantuvo las dimensiones alcanzadas para dichas clases. Conclusiones: Se demostró la efectividad del tratamiento al encontrarse el porcentaje de categorías, favorable y medianamente favorable por encima del estándar establecido.

ABSTRACT Introduction: coronally repositioned flap associated with subepithelial connective tissue graft constitutes a treatment modality used for root coverage that allows increasing the indications for this procedure and increases the stability of the outcomes over time. Objective: to evaluate the outcomes of the treatment of periodontal recession using coronally repositioned flap associated with subepithelial connective tissue five years after surgery. Methods: a longitudinal and descriptive study was carried out on patients five years after surgery, from January 2020 to October 2021 in the Dental Faculty at Villa Clara University of Medical Sciences. The population consisted of patients operated on with the coronally repositioned flap technique associated with subepithelial connective tissue from March 2014 to December 2016. Two units of analysis were used: patients and teeth with periodontal recession. Age, gender, Miller's classes, length and coverage of the recession, gain of attached gingiva, aesthetic appearance and evaluation categories were the used variables. Results: the percentage of root coverage after five years had a slight decrease that was not statistically significant for Miller's classes I and II (p>0.05). The width of the attached gingiva maintained the dimensions achieved for these classes. Conclusions: the effectiveness of the treatment was demonstrated favourable and moderately favourable above the established standards when finding the percentage of categories.

Aim This study aimed to evaluate the millimeter distances and active tip diameters of different periodontal probes. Methods Two types of periodontal probes were analyzed (North Carolina (15-UNC) and PCP-12). Two manufacturers were selected for each probe type. Digital images of the probes were obtained and the distances were measured using a software program. The diameter of the active tip was measured using a digital caliper. Both variables were measured by two trained and calibrated examiners. The data were analyzed using the Bland-Altman method and two-way ANOVA with Tukey’s post-hoc test. Statistical significance was set at p<0.05. Results A comparison of measurements between the 15-UNC and PCP-12 probes showed a significant difference in all millimeter markings. The 15-UNC probe showed differences between the 3 and 12 mm markings. The PCP-12 probe only showed differences between the marks at the 12 mm mark. The 15-UNC probe had a similar active tip diameter between the two manufacturers. The PCP-12 probe showed a significant difference between the two manufacturers. Both types of probes had similar active tip diameters when compared by the two manufacturers. Conclusion There was no standardization in relation to millimeter marks and tip diameters of the two types of periodontal probes produced by the two different manufacturers. The probe types exhibited little variability. North 15UNC UNC 15 (15-UNC PCP12. PCP12 PCP . PCP-12) type program caliper examiners BlandAltman Bland Altman twoway way Tukeys Tukey s posthoc post hoc test p005 p 0 05 p<0.05 PCP-1 markings 1 mark variability PCP1 p00 p<0.0 PCP- p0 p<0. p<0 p<

Aim Cyclooxygenase enzymes (COX) catalyze the conversion of arachidonic acid to prostaglandins and thromboxanes during pain and inflammation conditions. These enzymes have also been linked to several other conditions and diseases, and hence, in dentistry, it is crucial to identify the processes that increase the levels of these mediators. This paper aims to describe the significance of COX in dental practice through a narrative review. Methods Articles relating to COX upregulation published in English and Spanish over the last 51 years in databases such as EBSCO, Google Scholar, Science Direct, PubMed, and Web of Science; were analyzed. Results A total of 115 articles demonstrating the relationship between COX upregulation and multiple conditions and diseases of importance in prosthodontics, periodontics, oral pathology, orthodontics, and endodontics were included. Conclusions COX upregulation is related to inflammatory and malignant diseases in oral tissues, such as periodontitis, pulpitis, and oral cancer, nevertheless, its expression is advantageous in other fields of study such as orthodontics. Additionally, is well documented that dental materials provoke an undesired increase in COX expression, which could be a significant factor that directly affects pulpal health. (COX hence dentistry mediators review 5 EBSCO Scholar Direct PubMed analyzed 11 prosthodontics periodontics pathology orthodontics included tissues periodontitis pulpitis cancer nevertheless Additionally health 1

Resumo Esta meta-pesquisa buscou avaliar a conduta, o relato e as principais características de ensaios clínicos randomizados (ECRs) publicados na odontologia. Foi realizada uma busca no PubMed por ECRs em odontologia indexados de 31 de dezembro de 2016 a 31 de dezembro de 2021. Dois revisores avaliaram independentemente os estudos quanto à presença dos critérios de elegibilidade. Apenas estudos em inglês foram considerados. Dados do periódico e do autor, especialidade, métricas de citação e publicação, detalhes de relato e conduta dos estudos foram coletados. Uma análise descritiva dos dados, um mapa mostrando o número de ECRs por país e um gráfico de rede da colaboração científica entre diferentes países foram apresentados. Incluímos 844 artigos. A principal área de pesquisa foi a periodontia (16,35%). O maior número de ECRs foi atribuído ao Brasil (16,59%). Autores dos EUA estabeleceram a maioria das conexões com outros países. A maioria dos estudos não relatou o uso do CONSORT (67,89%), o tipo de randomização (69,31%) ou o mecanismo usado para implementar a sequência de alocação randomizada (52,37%). No entanto, a maioria dos estudos incluiu "randomized" no título (71,92%) e relatou o método para gerar uma sequência de alocação randomizada (65,88%) e o cegamento (74,88%). Os ECRs são a base para a tomada de decisões clínicas. Nossos resultados fornecem uma visão mais clara dos ECRs atuais e identificam áreas que requerem melhorias. O Brasil foi o país que mais produziu ECRs, e os EUA foram o principal colaborador. Ressaltamos a variabilidade das características de relato e conduta do estudo. metapesquisa meta (ECRs 3 201 2021 elegibilidade considerados autor especialidade publicação coletados dados apresentados 84 artigos 16,35%. 1635 16,35% . 16 35 (16,35%) 16,59%. 1659 16,59% 59 (16,59%) 67,89%, 6789 67,89% , 67 89 (67,89%) 69,31% 6931 69 (69,31% 52,37%. 5237 52,37% 52 37 (52,37%) entanto randomized "randomized 71,92% 7192 71 92 (71,92% 65,88% 6588 65 88 (65,88% 74,88%. 7488 74,88% 74 (74,88%) clínicas melhorias colaborador estudo 20 202 8 163 16,35 1 (16,35% 165 16,59 5 (16,59% 678 67,89 6 (67,89% 69,31 693 (69,31 523 52,37 (52,37% 71,92 719 7 9 (71,92 65,88 658 (65,88 748 74,88 (74,88% 2 16,3 (16,35 16,5 (16,59 67,8 (67,89 69,3 (69,3 52,3 (52,37 71,9 (71,9 65,8 (65,8 74,8 (74,88 16, (16,3 (16,5 67, (67,8 69, (69, 52, (52,3 71, (71, 65, (65, 74, (74,8 (16, (67, (69 (52, (71 (65 (74, (16 (67 (6 (52 (7 (74 (1 ( (5

Abstract This meta-research sought to evaluate the conduct, reporting, and main characteristics of published randomized controlled trials (RCTs) in dentistry. A search was performed on PubMed for RCTs in dentistry indexed from 31 December 2016 to 31 December 2021. Two reviewers independently screened the studies for the presence of eligibility criteria. Only studies in English were considered. Journal and author data, subject, citation and publishing metrics, reporting, and details of study conduct were collected. A descriptive analysis of the data, a map depicting the number of RCTs per country, and a network graph of scientific collaboration among different countries were presented. We included 844 articles. The main research area was periodontics (16.35%). The highest number of RCTs was attributed to Brazil (16.59%). Authors from the USA established the most links with other countries. Most studies did not report the use of CONSORT (67.89%), the type of randomization (69.31%), or the mechanism used to implement the random allocation sequence (52.37%). However, most studies included “randomized” in the title (71.92%) and reported the method for generating a random allocation sequence (65.88%) and blinding (74.88%). RCTs are the basis for clinical decision-making. Our results provide a better view of current RCTs and identify areas that require improvement. Brazil was the country that produced the most RCTs, and the USA was the main collaborator. We emphasize the variability of reporting characteristics and study conduct. metaresearch meta (RCTs 3 201 2021 criteria considered data subject metrics collected presented 84 articles 16.35%. 1635 16.35% . 16 35 (16.35%) 16.59%. 1659 16.59% 59 (16.59%) 67.89%, 6789 67.89% , 67 89 (67.89%) 69.31%, 6931 69.31% 69 (69.31%) 52.37%. 5237 52.37% 52 37 (52.37%) However “randomized 71.92% 7192 71 92 (71.92% 65.88% 6588 65 88 (65.88% 74.88%. 7488 74.88% 74 (74.88%) decisionmaking. decisionmaking decision making. making decision-making improvement collaborator 20 202 8 163 16.35 1 (16.35% 165 16.59 5 (16.59% 678 67.89 6 (67.89% 693 69.31 (69.31% 523 52.37 (52.37% 71.92 719 7 9 (71.92 65.88 658 (65.88 748 74.88 (74.88% 2 16.3 (16.35 16.5 (16.59 67.8 (67.89 69.3 (69.31 52.3 (52.37 71.9 (71.9 65.8 (65.8 74.8 (74.88 16. (16.3 (16.5 67. (67.8 69. (69.3 52. (52.3 71. (71. 65. (65. 74. (74.8 (16. (67. (69. (52. (71 (65 (74. (16 (67 (69 (52 (7 (6 (74 (1 (5 (

Abstract This study evaluated the scientific contribution of Brazilian CNPq Research Productivity fellows (PQ) in Dentistry by areas of activity. This cross-sectional study included 217 active PQ who were grouped into six groups: (1) Biomaterials, Prosthodontics, and Restorative Dentistry; (2) Public Health and Epidemiology; (3) Oral Pathology, Stomatology, and Dental Radiology; (4) Pediatric Dentistry and Child Health; (5) Dental Clinic (Periodontics, Endodontics, Orthodontics, Oral Surgery, and Implantology), and (6) Basic Areas (Histology, Biochemistry, Molecular Biology, Physiology, Microbiology, Immunology, and Pharmacology). The PQ were predominantly male (n = 122; 56.2%), received level 2 scholarships (n = 121; 55.8%), and performed research in the Southeast region of Brazil (n = 160; 73.73%). Regarding supervision of undergraduate, master's, and PhD students, both during their entire careers and in the last 5 years, the highest average was observed for PQs in the field of Public Health and Epidemiology, the only area with higher average supervision of master's than that of undergraduate and PhD students. PQ in Public Health and Epidemiology had the highest average number of papers published over their career and in the last 5 years, followed by PQ in Pediatric Dentistry and Child Health and Dental Clinic. The high productivity of PQ is demonstrated by modern research performance indicators. Their scientific publications are indexed in bibliometric databases such as WoS, Scopus, and SciELO. Addtionally, highlighted among the PQ was the time since initiation of their scientific careers and master's and doctoral candidates trained. (PQ activity crosssectional cross sectional 21 groups 1 (1 Biomaterials Prosthodontics (2 3 (3 Pathology Stomatology Radiology 4 (4 (5 Periodontics, Periodontics (Periodontics Endodontics Orthodontics Surgery Implantology, Implantology , Implantology) 6 (6 Histology, Histology (Histology Biochemistry Biology Physiology Microbiology Immunology Pharmacology. Pharmacology . Pharmacology) n 122 56.2%, 562 56.2% 56 56.2%) 121 55.8%, 558 55.8% 55 8 55.8%) 160 73.73%. 7373 73.73% 73 73.73%) masters, masters master s, s students years indicators WoS Scopus SciELO Addtionally trained ( 12 56.2 55.8 16 737 73.73 7 56. 55. 73.7 73.

Resumen La Sociedad Argentina de Periodoncia ha formulado un Comentario, analizando los condicionantes del contexto nacional, para determinar si las recomendaciones generadas en la Guía de Práctica Clínica de nivel S3 de la Federación Europea de Periodoncia para el tratamiento de la periodontitis en estadios I-III, podrían ser aplicadas para dar respuesta a la demanda de la población, en lo referido a la salud periodontal.

Abstract The Argentine Society of Periodontics has formulated a Commentary, analyzing the determining factors of the national context, to determine if the recommendations generated in the Level S3 Clinical Practice Guideline of the European Federation of Periodontics for the treatment of periodontitis in stages I-III could be applied to respond to the demand of the population, regarding periodontal health.

Resumen Se realizó una revisión sistemática de la literatura en las bases de datos ScienceDirect, PubMed y SciELO. Como criterios de inclusión se tomaron en cuenta artículos originales, de texto completo que incluyeran el uso de nanopartículas (0-100 nm) con fines de regeneración periodontal publicados de 2016 a mayo del 2022. Los términos de búsqueda fueron “Periodontal regeneration AND nanoparticles AND dental materials”. Se obtuvieron y analizaron 13 artículos que cumplieron los criterios de inclusión y exclusión. Se encontró que la nanohidroxiapatita tiene alto efecto regenerador, seguido de nanopartículas de dióxido de titanio, oro, fosfato de calcio, quitosano y óxido de hierro, entre otras. Estas nanopartículas mostraron efecto de regeneración periodontal de una a cuatro semanas promoviendo principalmente las propiedades de osteoinducción, citocompatibilidad, adherencia celular, degradabilidad, analgesia y biomineralización. La nanotecnología en el campo odontológico está emergiendo como una plataforma atractiva para la terapia avanzada en conjunto con los biomateriales dentales. En esta revisión se encontró que las nHA y TiO2NPs mostraron la mejor respuesta celular en el menor tiempo para obtener resultados regenerativos en periodoncia en comparación con otros tipos de NPs utilizadas. Aún hay muy pocas NPs analizadas con fines de regeneración periodontal, por lo que su estudio es un área emergente; sin olvidarnos de las posibles limitantes, consecuencias y efectos adversos a corto y largo plazo, los cuales deben ser estudiados con mayor profundidad.

Abstract To carry out a systematic review of the literature to identify the types of nanoparticles and the effect they have on periodontal regeneration, a systematic review of the literature was carried out in the ScienceDirect, PubMed and SciELO databases. As inclusion criteria, the full-text original articles that included the use of nanoparticles (0-100 nm) for periodontal regeneration purposes published between 2016 and 2022 were taken into account. The search terms were “Periodontal regeneration AND nanoparticles AND dental materials”. 13 articles that met the inclusion and exclusion criteria were obtained and analyzed. nHA was found to have a high regenerative effect, followed by TiO2NPs, gold, calcium phosphate, chitosan, and iron oxide, among others. These NPs showed a periodontal regeneration effect for one to four weeks, mainly promoting osteoinduction, cytocompatibility, cell adherence, degradability, analgesia and biomineralization properties. Nanotechnology in the dental field is emerging as an attractive platform for advanced therapy in conjunction with dental biomaterials. In this review, it was found that nHA and TiO2NPs showed the best cellular response and in the shortest time to obtain regenerative results in periodontics in comparison to other NPs. There are still very few NPs analyzed for periodontal regeneration purposes, so their study is an emerging area. It is essential to recognize the possible limitations, consequences and adverse effects in short and long term, which must be studied in greater depth.