Abstract Despite an economy based mostly on agriculture, literature on viral diseases of plants is scarce in Paraguay. Only recently, researches on plant viruses took an impulse resulting in a precise identification of many of them affecting plants either cultivated or not. To provide reliable information regarding plant viruses present in Paraguay, an annotated list of them was prepared, covering descriptions from 1920 to present day. There have been some important outbreaks with severe yield losses in crops as cucurbits, citrus, sesame, bean, maize, peanuts and tomato. Many of older descriptions are included for their historical significance, but most identifications made require confirmation. On the other hand, recent descriptions have been completed, based on several assays, especially molecular characterization. This list is organized alphabetically following scientific names of the plant species found naturally infected by viruses, with comments about symptoms, geographical distribution, incidence, identification procedures, and other information, with due literature references. It is based on a compilation of publications made on plant virus diseases in Paraguay. Described virus species, in a total of 38 recognized by ICTV, belonging to 17 different genera (Alphaendornavirus, Ampelovirus, Begomovirus, Benyvirus, Carlavirus, Cilevirus, Closterovirus, Comovirus, Cucumovirus, Dichorhavirus, Fabavirus, Luteovirus, Ophiovirus, Orthotospovirus, Potexvirus, Potyvirus and Tobamovirus), besides two unclassified, and four unidentified. There is also a case of viroid described in Citrus spp. Infections caused by potyviruses are the most numerous. These viruses were described in more than 40 plant species, belonging to 18 botanical families. Because of crop diversity and richness in native flora, many more viruses must be present in Paraguay, which future works will certainly reveal, especially with the increase in manpower involving researches, especially cooperative with foreign centers, on plant viruses, which has been very limited until now. Also, knowledge on existing viruses may have relevance in understanding their epidemiology and provide the basis for their control strategies and quarantine measures, to avoid new variants of existing viruses or new viruses being introduced. agriculture Paraguay recently not prepared 192 day cucurbits citrus sesame bean maize tomato significance confirmation hand completed assays characterization symptoms distribution incidence procedures references 3 ICTV 1 Alphaendornavirus, Alphaendornavirus (Alphaendornavirus Ampelovirus Begomovirus Benyvirus Carlavirus Cilevirus Closterovirus Comovirus Cucumovirus Dichorhavirus Fabavirus Luteovirus Ophiovirus Orthotospovirus Potexvirus Tobamovirus, Tobamovirus , Tobamovirus) unclassified unidentified spp numerous 4 families flora reveal centers now Also measures introduced 19

Resumo A pesar de una economía basada principalmente en la agricultura, la literatura sobre enfermedades virales de las plantas es escasa en Paraguay. Sólo recientemente se han impulsado las investigaciones sobre los virus de plantas, lo que ha permitido identificar con precisión muchos de ellos que afectan a plantas cultivadas o no. Para brindar información confiable sobre los virus de plantas presentes en el Paraguay, se elaboró una lista comentada de los mismos, abarcando descripciones desde 1920 hasta la actualidad. Se han producido algunos focos importantes con severas pérdidas de rendimiento en cultivos de cucurbitáceas, cítricos, sésamo, frijol, maíz, maní y tomate. Muchas de las descripciones más antiguas se incluyen por su importancia histórica, pero la mayoría de las identificaciones realizadas requieren confirmación. Por otro lado, las descripciones recientes han sido completadas, basadas en varios ensayos, especialmente de caracterización molecular. Esta lista está organizada alfabéticamente siguiendo los nombres científicos de las especies de plantas que se encontraron naturalmente infectadas por virus, con comentarios sobre síntomas, distribución geográfica, incidencia, procedimientos de identificación y otras informaciones, con las debidas referencias bibliográficas. Se basa en una recopilación de publicaciones realizadas sobre enfermedades virales de plantas en Paraguay. Especies de virus descritas, en un total de 38 reconocidas por el ICTV, pertenecientes a 17 géneros diferentes (Alphaendornavirus, Ampelovirus, Begomovirus, Benyvirus, Carlavirus, Cilevirus, Closterovirus, Comovirus, Cucumovirus, Dichorhavirus, Fabavirus, Luteovirus, Ophiovirus, Orthotospovirus, Potexvirus, Potyvirus y Tobamovirus), además de dos sin clasificar y cuatro sin identificar. También existe un caso de un viroide descrito en Citrus spp. Las infecciones causadas por potyvirus son las más numerosas. Estos virus fueron descritos en más de 40 especies de plantas, pertenecientes a 18 familias botánicas. Debido a la diversidad de cultivos y la riqueza de la flora nativa, muchos más virus deben estar presentes en Paraguay, lo que seguramente revelarán trabajos futuros, especialmente con el aumento de la mano de obra involucrada en investigaciones, en cooperación con centros extranjeros, sobre virus de plantas, que ha sido muy limitada hasta el momento. Además, el conocimiento sobre los virus existentes puede ser relevante para comprender su epidemiología y proporcionar una base para sus estrategias de control y medidas de cuarentena, para evitar la introducción de nuevas variantes de virus existentes o nuevos virus. agricultura Paraguay no mismos 192 actualidad cucurbitáceas cítricos sésamo frijol maíz tomate histórica confirmación lado completadas ensayos molecular síntomas geográfica incidencia informaciones bibliográficas descritas 3 ICTV 1 Alphaendornavirus, Alphaendornavirus (Alphaendornavirus Ampelovirus Begomovirus Benyvirus Carlavirus Cilevirus Closterovirus Comovirus Cucumovirus Dichorhavirus Fabavirus Luteovirus Ophiovirus Orthotospovirus Potexvirus Tobamovirus, Tobamovirus , Tobamovirus) spp numerosas 4 botánicas nativa futuros extranjeros momento Además cuarentena 19

ABSTRACT Peanuts are mainly grown in sandy soils with low boron content, which may limit the crop yield, especially runner-type cultivars that have high-yields. Boron deficiency causes hollow heart in peanut seeds, reducing yield and seed quality, but the best strategy to supply boron to peanut is still not known. This study aimed to evaluate peanuts nutrition, yield, and seed quality as a function of boron rate, source, and application form. The study was conducted for two years in sandy soils with low boron in southeastern Brazil. Treatments included application of boron via soil: control (boron unfertilized), boric acid at 1.5 kg ha-1 of B, Ulexite (1.5 and 3.0 kg ha-1 of B), and sodium tetraborate (1.5 and 3.0 kg ha-1 of B) combined with foliar fertilization (sub-plots): 0, 400, 800 and 1200 g ha-1 of B (boric acid) with four replicates. Boron fertilization via soil and foliar increased peanuts yield by 20 % (1100 kg ha-1) and 14 % (700 kg ha-1) - the average of the two crops, respectively. Combined use of soil and foliar fertilizer was justified only in years with water deficit and when the rate applied via soil was low (<3.0 kg ha-1). Boron application via soil or application of 400 g ha-1 of B via foliar fertilization increased seed germination rate by 10 to 13 %. Boron fertilization increased the percentage of normal seedlings, seedling weight, and length and reduced the germination time. Foliar and soil boron applications efficiently improved peanut seed nutrition, yield, and quality. However, soil application performed better, showing a higher percentage of yield increase. content runnertype runner type highyields. highyields high yields. yields high-yields seeds known nutrition source form Brazil unfertilized, unfertilized , unfertilized) 15 1 5 1. ha1 ha ha- (1. 30 3 0 3. subplots sub plots (sub-plots) 80 120 replicates 2 1100 (110 700 (70 crops respectively <3.0 (<3. ha1. . 40 seedlings weight time However better increase (1 (sub-plots 8 12 110 (11 70 (7 <3. (<3 4 ( 11 7 <3 (< <

ABSTRACT The success of intercropping depends on the spatial arrangement between crops, aiming at the best use of the planting area and greater profitability for the farmer. Here, we evaluated the effect of cassava-peanut intercropping on several agronomic parameters. The research was carried out in the APTA experimental area, in the state of São Paulo, Brazil. The experimental design was randomized blocks with four treatments (peanut in monoculture - P; cassava in monoculture - C, cassava intercropped with peanuts planted between rows - CPb, and intercropping in alternating double rows - CPd) and eight replications. The variables analyzed were vegetative growth of cassava plants, soil vegetation cover and weed control, incidence of the main cassava and peanut pests, productivity, and the land equivalent ratio (LER). Only CPb inhibited cassava vegetative growth, significantly affecting its final height. Greater vegetation coverage and, consequently, lower occurrence of weeds, was obtained in CPb in addition to lower incidence of whiteflies in cassava. The intercropping system, regardless of the spatial arrangement used, increased the incidence of the lace bug in cassava and reduced the incidence of peanut pests. Crop productivity was lower in CPd due to the lower planting density of intercrops. However, both intercropping arrangements increased LER. Thus, despite the spatial arrangement of the intercropping system having implied different agronomic responses of the crops, planting peanuts between the cassava rows brought the best agronomic results. crops farmer Here cassavapeanut parameters Paulo Brazil P C replications plants control pests LER . (LER) height consequently weeds used intercrops However Thus results (LER

RESUMO O sucesso de consorcio de culturas depende da boa disposição espacial entre elas, caracterizando o melhor uso da área de plantio e maior rentabilidade para o agricultor. Nesse trabalho avaliamos o efeito do consórcio entre mandioca e amendoim em diferentes aspectos agronômicos. A pesquisa foi realizada na área experimental da APTA, no estado de São Paulo, Brasil. O delineamento experimental foi de blocos ao acaso com quatro tratamentos e oito repetições. Os tratamentos foram: amendoim em monocultura (P); mandioca em monocultura (C), consórcio com o amendoim plantado na entrelinha das fileiras mandioca (CPb), e consórcio das culturas em fileiras duplas alternadas (CPd). As variáveis analisadas foram crescimento vegetativo das plantas de mandioca, cobertura do solo e controle de ervas daninhas, incidência das principais pragas da mandioca e do amendoim, produtividade das culturas consortes e o índice de uso da terra (LER). Apenas CPb inibiu o crescimento vegetativo da mandioca, afetando significativamente sua altura final. CPb obteve maior cobertura vegetal e, consequentemente, menor ocorrência de ervas daninhas, além de resultar em menor incidência de mosca-branca na mandioca. O consorcio, independente do arranjo espacial utilizado aumentou a incidência do percevejo de renda na mandioca e diminuiu a incidência das pragas do amendoim. A produtividade das culturas menor em CPd, devido a menor densidade de plantio das culturas consortes. Porém qualquer arranjo do consorcio dessas culturas aumenta a LER. Assim, apesar do arranjo espacial do consórcio ter implicado diferentes respostas agronômicas das culturas, o plantio de amendoim na entrelinha da mandioca trouxe os melhores resultados agronômicos. elas agricultor agronômicos APTA Paulo Brasil repetições P (P) C, C , (C) CPb, (CPb) CPd. CPd . (CPd) daninhas LER (LER) final consequentemente moscabranca mosca branca Assim (P (C (CPb (CPd (LER

RESUMO Os números de hoje mostram efetivamente que estamos na Terceira Guerra Mundial. Não é um país contra o outro, mas cada país contra um vírus diferente e, por vezes, o mundo contra um único vírus e suas mutações. O Brasil está agora no meio de uma nova epidemia, a de dengue causada por um arbovírus. Muitas pesquisas estão em andamento, em vários países, na busca de novos alvos terapêuticos em diferentes vírus, tanto para a terapia antiviral quanto para a produção de vacinas. Alguns vírus são dependentes de aminoácidos para a formação de suas proteínas e o equilíbrio de dois aminoácidos, a L-lisina e a L-arginina, talvez seja uma possível terapia também contra os arbovírus. Até que sejam realizados novos estudos, o equilíbrio arginina/lisina deve ser observado mais atentamente em pacientes portadores de vírus. Seria interessante, nestes pacientes, manter pelo menos um equilíbrio na dieta com o consumo de alimentos ricos em lisina e o controle na ingestão de alimentos ricos em arginina como o chocolate, o amendoim, os cereais, o caju e as castanhas em geral, nos primeiros dias da infecção viral, fase de maior de multiplicação do vírus. Esse protocolo talvez possa ser aplicado nos casos de infecções por arbovírus. Mundial outro vezes mutações epidemia arbovírus andamento países vacinas Llisina L Larginina, Larginina arginina, L-arginina estudos argininalisina interessante chocolate amendoim cereais geral viral

ABSTRACT Today’s numbers effectively show that we are in World War III. It is not one country against another, but each country against a different virus and, sometimes, the world against a single virus and its mutations. Brazil is now in the midst of a new epidemic, dengue (break-bone fever) caused by an arbovirus. Much research is underway, in several countries, in the search for new therapeutic targets in different viruses, both for antiviral therapy and for vaccine production. Some viruses are dependent on amino acids for the formation of their proteins and the balance of two amino acids, L-lysine and L-arginine, may also be a possible therapy against arboviruses. Until new studies are carried out, the arginine/lysine balance should be observed more closely in patients with viruses. It would be interesting, in these patients, to maintain at least a balance in the diet with the consumption of foods rich in lysine and control the intake of foods rich in arginine such as chocolate, peanuts, cereals, cashews and nuts in general, in first days of the viral infection, the phase of greatest virus multiplication. This protocol could perhaps be applied in cases of arboviruses infections. Todays Today s III another sometimes mutations epidemic breakbone break bone fever arbovirus underway countries production Llysine L Larginine, Larginine arginine, L-arginine out argininelysine interesting chocolate peanuts cereals general infection multiplication infections

Abstract Anaphylaxis, a potentially life-threatening reaction, is characterized by acute symptoms affecting various systems and requires immediate medical intervention. While the overall mortality rate is low, anaphylaxis induced by foods and drugs has seen an increase. Common triggers include foods, drugs, and Hymenoptera venom. Epidemiology varies by region and age, with a global incidence of 50-112 episodes per 100,000 people annually. Implicated foods vary by age and region, with peanuts and nuts being common triggers. Two mechanisms of anaphylaxis are recognized: IgE-mediated and non-IgE-mediated. Diagnosis is based on clinical criteria and serum tryptase levels. Treatment includes epinephrine, oxygen, and intravenous fluids. Exercise-induced food-dependent anaphylaxis is addressed, where exercise, combined with certain foods, triggers anaphylactic reactions. Proper understanding and management are crucial to mitigate risks.

Resumen La anafilaxia, una reacción potencialmente mortal, se caracteriza por la aparición aguda de síntomas que afectan diversos sistemas y requiere intervención médica inmediata. Aunque la tasa de mortalidad general es baja, la anafilaxia inducida por alimentos y fármacos ha experimentado un aumento. Los alimentos, fármacos y veneno de himenópteros son desencadenantes comunes. La epidemiología varía según la región y la edad, con una incidencia global de 50-112 episodios anuales por cada 100,000 personas. Los alimentos más implicados varían según la edad y la región, y los desencadenantes más comunes son cacahuetes y nueces. Se reconocen dos mecanismos de anafilaxia: mediado por IgE y no mediado por IgE. El diagnóstico se basa en criterios clínicos y niveles de triptasa sérica. El tratamiento incluye epinefrina, oxígeno y líquidos intravenosos. Se aborda la anafilaxia inducida por ejercicio dependiente de alimentos, donde el ejercicio, en combinación con ciertos alimentos, desencadena reacciones anafilácticas. La comprensión y el manejo adecuados son cruciales para mitigar riesgos.

Abstract The prevalence of food allergy has increased in some regions of the world, and with it the incidence, according to geographical variability, in the phenotype and clinical manifestations. Food allergy arises from the specific immune response induced by exposure to the proteins of a certain food. Food intolerance refers to non-immune reactions, caused by unique physiological characteristics of the individual, including metabolic, toxic, pharmacological and undefined mechanisms. Adverse reactions to foods are classified as: IgE-mediated: Type I Hypersensitivity, non-IgE-mediated: Type IV Hypersensitivity, mixed: Types I and IV Hypersensitivity Non-Allergic; toxic, pharmacological, metabolic, intolerances. These types of alterations are rare but have increased in recent years; These include protein-induced enterocolitis syndrome, which can cause emesis, diarrhea and hypotension, and shock, which begins two hours after ingestion of the allergen. Protein-induced allergic proctocolitis is a condition that includes allergy to cow's milk protein. Delayed reactions usually affect the digestive system, are more insidious in their onset and are not immediately controlled, even with the suspension of food. There are eight foods responsible for 90% of food llergies: milk, eggs, soy, wheat, peanuts, walnuts, fish, and shellfish.

Resumen La prevalencia de alergia alimentaria se ha incrementado en algunas regiones del mundo, y con ello la incidencia, según la variabilidad geográfica, en el fenotipo y manifestaciones clínicas. La alergia alimentaria surge de la respuesta inmune específica inducida por la exposición a las proteínas de cierto alimento. La intolerancia alimentaria se refiere a reacciones no inmunitarias, causadas por características fisiológicas únicas del individuo, que incluyen mecanismos metabólicos, tóxicos, farmacológicos e indefinidos. Las reacciones adversas a los alimentos se clasifican en: mediada por IgE: Hipersensibilidad Tipo I, no mediada por IgE: ipersensibilidad Tipo IV, mixtas: Hipersensibilidad Tipos I y IV No Alérgicas; tóxicas, farmacológicas, metabólicas, intolerancias. Este tipo de alteraciones son poco frecuentes, pero se ha incrementado en los últimos años; entre estas se encuentra el síndrome de enterocolitis inducida por proteínas, que puede producir emesis, diarrea e hipotensión, y estado de shock, que inicia dos horas después de la ingestión del alergeno. La proctocolitis alérgica inducida por proteínas es una afectación que incluye la alergia a la proteína e leche de vaca. Las reacciones retardadas suelen afectar el aparato digestivo, son más insidiosas en su inicio y no se controlan inmediatamente, aún con la suspensión del alimento. Existen ocho alimentos responsables del 90% de alergia alimentaria: leche, huevo, soya, trigo, cacahuate, nuez, pescados y mariscos.

Abstract In recent times, the primary approach to treating food allergies involved strict avoidance of the triggering allergen. Many considered this approach as lacking true treatment, leaving patients vulnerable to even small amounts or hidden sources of the allergenic food. Desensitization or Oral Tolerance Induction (OTI) is a studied method aiming for a lasting tolerance to the allergen. The ultimate goal is permanent tolerance, where allergic reactions won't reoccur after new exposure to the triggering allergen, following a period of abstinence. The research mainly focuses on allergen-specific immunotherapy, covering three routes: oral, sublingual, and epicutaneous immunotherapy. Milk, egg, and peanuts are the extensively studied foods due to their prevalence in allergies. The oral route is favored for inducing tolerance because ingestion of a food antigen by a non-allergic individual triggers an active immune response without causing an allergic reaction. The paradigm has shifted from recommending avoidance to early consumption strategies to prevent allergies. The period from 4 to 6 months of age is considered immunologically sensitive, where children with risk factors show increased allergic sensitization risk. Implementing these recommendations, considering family and community preferences, may reduce the burden of food allergies and healthcare costs.

Resumen Hasta hace poco, el enfoque principal para tratar las alergias alimentarias implicaba evitar estrictamente el alérgeno desencadenante. Este método a menudo se consideraba insuficiente, lo que dejaba a los pacientes vulnerables a pequeñas cantidades o fuentes ocultas del alérgeno. La desensibilización, o inducción de tolerancia oral, es un método emergente que se está investigando para el tratamiento de las alergias alimentarias. El objetivo final es conseguir una tolerancia permanente, previniendo reacciones alérgicas tras una nueva exposición al alérgeno tras un periodo de abstinencia. La investigación se ha centrado en la inmunoterapia con alérgenos específicos a través de tres vías: oral, sublingual y epicutánea. La leche, el huevo y el maní son los principales alimentos estudiados debido a su prevalencia en las alergias. Se prefiere la inducción oral porque la ingestión de una persona no alérgica induce una respuesta inmune sin desencadenar una reacción alérgica. La atención de pacientes se ha desplazado de evitar el alergeno a ofrecer estrategias de consumo temprano para prevenir las alergias. En este enfoque se considera crucial el rango de edad de 4 a 6 meses. Se necesita investigación continua para evaluar los detalles de la población, los efectos a largo plazo, la viabilidad y la seguridad de estas estrategias.

Abstract Food allergy is very common throughout the world and has become a major public health problem, with 220 million people suffering from it. Food allergy has been disproportionately observed in people from industrialized or Western countries and was previously considered to predominate in the pediatric versus adult population. However, the current exponential growth of the adult population and older adults, especially in Western countries, and environmental and lifestyle changes, have profoundly changed the epidemiology of food allergy, with a growing increase even at advanced ages. The foods that represent the greatest severity and clinical impact are peanuts, walnuts, fish, shellfish, eggs, cow's milk protein, wheat, soy and seeds. Although some types of food allergies (cow's milk and egg) may disappear, peanut and tree nut allergies may persist into adulthood. The control or cure of cow's milk protein allergy is gradual throughout childhood and adolescence. Despite the predominance of allergy to fish, shellfish, peanuts, and tree nuts in most reactions in adults, the most common form of IgE-mediated food allergy is oral allergy syndrome or pollen allergy syndrome. food.

Resumen La alergia alimentaria es muy común en todo el mundo y se ha convertido en un importante problema de salud pública, pues 220 millones de personas la padecen. La alergia alimentaria se ha observado de manera desproporcionada en personas de países industrializados u occidentales, y se considera previamente con predominio en la población pediátrica versus adultos. Sin embargo, el crecimiento exponencial actual de la población adulta y adultos mayores, especialmente en los países occidentales, y los cambios ambientales y de estilo de vida, han cambiado profundamente la epidemiología de la alergia alimentaria, con un aumento creciente incluso en edades avanzadas. Los alimentos que representan mayor gravedad y repercusión clínica son: cacahuate, nuez, pescado, mariscos, huevo, proteína de leche de vaca, trigo, soya y semillas. Aunque algunos tipos de alergia alimentaria (leche de vaca y huevo) pueden desaparecer, la alergia al cacahuete y la nuez de árbol pueden persistir hasta la edad adulta. El control o curación de la alergia a la proteína de leche de vaca es gradual a lo largo de la niñez y la adolescencia. A pesar del predominio de la alergia al pescado, mariscos, cacahuates y nueces de árbol en la mayoría de las reacciones en adultos, la forma más común de alergia alimentaria mediada por IgE en es el síndrome de alergia oral o síndrome de alergia al polen-alimento.

ABSTRACT Peanut cultivation has national and global significance in agriculture and industry. Under water-limited conditions, its yield decreases to the extent that it compromises the success of the exploitation. This study focused on evaluating peanut crop yield and production components under full and deficit irrigation applied in the reproductive phase, to determine the impact of water supply on the yield of peanuts grown in the off-season in the State of São Paulo, Brazil. The experiment was conducted for two years and followed a randomized blocks design with five irrigation levels distributed in strips, with four repetitions. The treatments consisted of crop evapotranspiration replenishments from 100 to 10%. In the first year, under suitable temperatures, the maximum yield reached 3,922 kg ha-1 with the application of 277 mm of irrigation depth and decreased up to 35% with the lowest irrigation depth (48 mm). In the second year, suboptimal temperatures caused a delay in the growing cycle and caused a 33% reduction in crop yields. Despite the potential benefits of deficit irrigation in increasing water productivity, low temperatures pose a risk to peanut yield, especially during the off-season crop in the region. industry waterlimited limited conditions exploitation phase offseason off season Paulo Brazil strips repetitions 10 10% year 3922 3 922 3,92 ha1 ha 1 ha- 27 35 48 (4 mm. . mm) 33 yields productivity region 392 92 3,9 2 4 ( 39 9 3,

RESUMO O cultivo do amendoim tem importância nacional e global na agricultura e na indústria. Em condições limitadas de água, sua produtividade diminui ao ponto de comprometer o sucesso da exploração. Este estudo teve como objetivo avaliar o rendimento da cultura do amendoim e seus componentes de produção sob irrigação plena e deficitária aplicada na fase reprodutiva, para determinar o impacto do fornecimento de água no rendimento do amendoim cultivado na segunda época no Estado de São Paulo, Brasil. O experimento foi conduzido durante dois anos e seguiu um delineamento de blocos ao acaso com cinco níveis de irrigação distribuídos em faixas, com quatro repetições. Os tratamentos consistiram na reposição da evapotranspiração da cultura de 100 a 10%. No primeiro ano, sob temperaturas adequadas, o rendimento máximo atingiu 3.922 kg ha-1 com a aplicação de uma lâmina de irrigação de 277 mm e diminuiu em até 35% com a menor lâmina (48 mm). No segundo ano, temperaturas subótimas causaram atraso no ciclo de crescimento e casou redução de 33% na produtividade da cultura. Apesar dos potenciais benefícios da irrigação deficitária no aumento da produtividade da água, as baixas temperaturas representam um risco para o rendimento do amendoim na segunda safra. indústria exploração reprodutiva Paulo Brasil faixas repetições 10 10% ano adequadas 3922 3 922 3.92 ha1 ha 1 ha- 27 35 48 (4 mm. . mm) 33 safra 392 92 3.9 2 4 ( 39 9 3.

RESUMO A produção de amendoim tem crescido anualmente no Brasil. Com as secas que ocorrem frequentemente em todas as regiões brasileiras, é necessário identificar germoplasma precoce para ser utilizado em trabalhos de melhoramento visando à adaptação ambiental. Aqui, uma mini coleção de amendoim foi estudada com o objetivo de selecionar germoplasma para uso posterior em procedimentos de melhoramento, com foco em ambiente com restrição hídrica. Doze características agronômicas foram adotadas e posteriormente utilizadas em métodos multivariados, baseados em modelos hierárquicos (UPGMA) e dispersão gráfica (variáveis canônicas), visando identificar agrupamentos de acessos precoces. Diferenças estatísticas significativas foram encontradas para a maioria das variáveis, indicando variabilidade genética nos acessos estudados. Com base nas análises multivariadas, verificou-se coerência na formação de três agrupamentos, um deles (G3: PI-268-689 e AHK-85-3) aglomerou os acessos mais promissores para produção de vagens e eficiência reprodutiva, previamente identificados na análise de variância. Portanto, ambos germoplasma são recomendados para uso em trabalhos de melhoramento voltados para o ambiente com restrição hídrica.

ABSTRACT Peanut production is growing annually in Brazil, but with frequent droughts throughout the country, it is necessary to identify an earliness germplasm for the improved environmental adaptation of peanuts. Here, a mini-core collection of peanuts was studied to select germplasms for further use in breeding, with a focus on dry environments. Twelve agronomic traits were adopted and later used in multivariate methods based on hierarchical models (UPGMA) and graphical dispersion (canonical variables), which aimed to identify earliness accession clusters. Statistically significant differences were found for most traits, indicating that there was genetic variability among accessions. Multivariate analyses subsequently revealed coherence in the formation of three clusters, one of which (G3: PI-268-689 and AHK-85-3) combined the most promising accessions for pod production and reproductive efficiency, previously identified through analysis of variance. Therefore, both germplasms are recommended here for use in future breeding studies focused on water-restricted environments.

Abstract Background Phytoremediation is a technique used in soils contaminated with residual herbicides, such as tebuthiuron. However, the herbicide presence in the soil and plant matrices are not generally quantified. Objective This study aimed to select plant species to evaluate the phytoremediation of 14C-tebuthiuron by showy rattlepod (Crotalaria spectabilis), sorghum (Sorghum bicolor), radish (Raphanus sativus), peanut (Arachis hypogaea), and alfalfa (Medicago sativa) in herbicide-contaminated soil. Methods The selection of the five herbicide phytoremediation plants was with the application of five rates of tebuthiuron (300, 600, 1,200, 2,400, and 4,800 g a.i. ha-1) and compared to a control. Peanuts and sorghum (herbicide-tolerant plants) were sown in soil contaminated with tebuthiuron (600 g a.i. ha-1) applied through a working solution containing 17.47 kBq of 14C-tebuthiuron. The total of herbicide was analyzed in the soil and plant at three phenological stages. Results Showy rattlepod, radish, and alfalfa were sensitive to the herbicide even at the lowest application rate. Sorghum was tolerant to the herbicide up to 600 g ha-1 with the application of 1,200 g ha-1, there was 80% injury; peanut was tolerant even at the highest rate (4,800 g ha-1) with only 40% injury. Peanut and sorghum were able to phytoremediate the soil, although, peanut was more efficient in decreasing tebuthiuron contamination by 76%, while sorghum reduced at by 45% at 3rd phenological stage. Conclusions Thus, both plants can be recommended in succession/rotation with crops that had tebuthiuron applied from pre-emergence weed control. herbicides However quantified 14Ctebuthiuron Ctebuthiuron 14C C Crotalaria spectabilis, spectabilis , spectabilis) bicolor, bicolor bicolor) Raphanus sativus, sativus sativus) Arachis hypogaea, hypogaea hypogaea) Medicago sativa herbicidecontaminated 300, 300 (300 1200 1 200 2400 2 400 2,400 4800 4 800 4,80 ai i a.i ha1 ha control herbicidetolerant (60 1747 17 47 17.4 14Ctebuthiuron. stages 60 ha- 1,20 ha1, 1, 80 injury (4,80 40 although 76 76% 45 rd stage Thus successionrotation succession rotation preemergence pre emergence 30 (30 120 20 240 2,40 480 4,8 (6 174 17. 6 1,2 8 (4,8 7 3 (3 12 24 2,4 48 4, ( (4, 2, (4

ABSTRACT: The pequi has an almond with interesting chemical characteristics, such as considerable proportions of proteins and lipids that can be applied in several products aiming to use this agro-industrial residue. This research tookadvantage of the almond for the development of sweet paçoca with different concentrations of pequi almond, containing 0% (PA), 25% (P1), 50% (P2), 75% (P3), and 100% (P4) in place of peanuts. The paçocas were evaluated for proximate parameters and water activity, mineral content, color parameters, microbiological characteristics, and texture profile. The results for aw ranged from 0.48 to 0.52. In the proximate composition, it was observed that with the increase of the almond flour there was a difference in the ash, moisture, and protein contents. Due to the almond roasting process, the paçocas of pequi presented the darkest color. Pequi almond paçocas showed better protein value than peanut paçoca and higher levels of P and Mg. In addition, they present better elasticity, chewability, and cohesiveness. ABSTRACT characteristics agroindustrial agro industrial residue 0 PA, PA , (PA) 25 P1, P1 (P1) 50 P2, P2 (P2) 75 P3, P3 (P3) 100 P4 (P4 peanuts activity content profile 048 48 0.4 052 52 0.52 composition ash moisture contents process Mg addition elasticity chewability cohesiveness (PA 2 (P1 5 (P2 7 (P3 10 (P 04 4 0. 05 0.5 1

RESUMO: O pequi possui uma amêndoa com características químicas interessantes, como proporções consideráveis de proteínas e lipídios que podem ser aplicadas em diversos produtos visando o aproveitamento desse resíduo agroindustrial. O objetivo deste trabalho foi aproveitar a amêndoa para o desenvolvimento de paçoca doce com diferentes concentrações de amêndoa de pequi, contendo 0% (PA), 25% (P1), 50% (P2), 75% (P3), e 100% (P4). As paçocas foram avaliadas quanto aos parâmetros centesimais e atividade de água, teor de minerais, parâmetros de cor, características microbiológicas e perfil de textura. Os resultados para aw variaram de 0,48 a 0,52. Na composição centesimal, observou-se que com o aumento da farinha de amêndoa houve diferença nos teores de cinzas, umidade e proteína. Devido ao processo de torrefação da amêndoa, as paçocas de pequi apresentaram cor mais escura. A paçoca de amêndoa de pequi apresentou melhor valor proteico que a paçoca de amendoim e maiores teores de P e Mg. Além disso, apresentaram melhor elasticidade, mastigabilidade e coesividade. RESUMO interessantes agroindustrial 0 PA, PA , (PA) 25 P1, P1 (P1) 50 P2, P2 (P2) 75 P3, P3 (P3) 100 P4. P4 . (P4) água minerais textura 048 48 0,4 052 52 0,52 centesimal observouse observou se cinzas proteína escura Mg disso elasticidade coesividade (PA 2 (P1 5 (P2 7 (P3 10 (P4 04 4 0, 05 0,5 (P 1

ABSTRACT: Salmonella is a relevant pathogen, which causes foodborne outbreaks associated with both high and low moisture foods (LMF). This study evaluated the effect of previous desiccation stress on the acid resistance of S. Typhimurium ATCC 14028 using blanched peanut kernels as an LMF model. Salmonella was recovered from the peanut samples throughout 180 days of blanched peanut kernels storage at 28 ºC. During this period two death rates were verified, 0.04 log cfu/g/day in the first 30 days and 0.007 log cfu/g/day between 30 and180 days.Regarding acid resistance, there was no difference (P > 0.05) in the Salmonella growth/death kinetics between the undesiccated sample (TSB)and the cells recovered from peanut samples over 180 days of storage after 4 h at pHs 3.0, 3.5, 4.5 and 7.2. The average growth rate observed for pH 7.2 was 0.44 log cfu/ml/h. At pH 4.5, the Salmonella counts did not change significantly over 4 h. In contrast, Salmonella populations declined by 0.14 to 0.29 log cfu/ml/h at pH 3.5. At pH 3.0 declines were estimated to be 0.65 log cfu/ml/h for the undesiccated sample and 2.07 log cfu/ml/h for Salmonella recovered from peanuts stored for 120 days. Therefore, our data indicated that desiccation stress caused during the peanut storagedid not influence the Salmonella acid resistance. ABSTRACT pathogen LMF. . (LMF) S 1402 model 18 2 ºC verified 004 0 04 0.0 cfugday cfu g day 3 0007 007 0.00 and18 daysRegarding Regarding P 0.05 005 05 growthdeath TSBand TSB 35 5 3.5 45 4. 72 7 7. 044 44 0.4 cfumlh ml contrast 014 14 0.1 029 29 0.2 3. 065 65 0.6 207 07 2.0 12 Therefore (LMF 140 1 00 0. 000 and1 01 02 06 6 20 2.

RESUMO: Em alimentos de baixa umidade (LMF), o primeiro desafio encontrado por patógenos como a Salmonella é o estresse de dessecação. Neste estudo, o efeito prévio do estresse de dessecação sobre a resistência ácida de S. Typhimurium ATCC 14028 foi avaliado utilizando amendoim blancheado como um modelo de LMF. Salmonella foi recuperada das amostras de amendoim após 180 dias de estocagem a 28 ºC. Durante este período foram verificadas duas taxas de mortalidade, 0,04 log ufc/g/dia nos primeiros 30 dias e 0,007 log ufc/g/dia entre 30 e 180 dias. Com relação à resistência ácida, não houve diferença (P > 0,05) na cinética de crescimento/morte de Salmonella entre a amostra sem estresse dessecativo (TSB) e as amostras de amendoim após 4 h em pHs 3,0, 3,5, 4,5 e 7,2. A taxa média de crescimento observada para o pH 7,2 foi de 0,44 log cfu/ml/h. No pH 4,5, a contagem de Salmonella não mudou significativamente durante 4 h. Em contraste, a população de Salmonella diminuiu de 0,14 a 0,29 log cfu/ml/h no pH 3,5. No pH 3,0, a queda foi estimada em 0,65 log cfu/ml/h para a amostra sem estresse dessecativo e 2,07 log cfu/ml/h para a Salmonella recuperada das amostras de amendoim estocadas por 120 dias. Portanto, nossos dados indicaram que o estresse dessecativo causado durante a estocagem do amendoim não influenciou a resistência ácida de Salmonella. RESUMO LMF, LMF , (LMF) estudo S 1402 18 2 ºC mortalidade 004 0 04 0,0 ufcgdia ufc g dia 3 0007 007 0,00 P 0,05 005 05 crescimentomorte morte TSB (TSB 3,0 35 5 3,5 45 4, 72 7 7, 044 44 0,4 cfumlh cfu ml contraste 014 14 0,1 029 29 0,2 065 65 0,6 207 07 2,0 12 Portanto (LMF 140 1 00 0, 000 3, 01 02 06 6 20 2,

Abstract Objective The prevalence of food allergies (FA) has increased worldwide over the last few decades. Milk, eggs, and peanuts are among the most common allergens and can cause anaphylaxis. Therefore, we aimed to identify biomarkers that could predict the persistence and/or severity of IgE-mediated allergies to milk, eggs, and peanuts via a systematic review. Methods This systematic review proceeded according to a protocol registered in the International Prospective Register of Systematic Reviews. Two independent authors extracted studies of interest from PubMed, SciELO, EMBASE, Scopus, and Ebsco databases and assessed their quality using the Newcastle-Ottawa Scale. Results We selected 14 articles describing 1,398 patients. Among eight identified biomarkers, total IgE, specific IgE (sIgE), and IgG4 were the most often cited biomarkers of persistent allergies to milk, eggs, and peanuts. Skin prick tests, endpoint tests, and sIgE cutoff levels may predict positive responses to challenges with these foods. The basophil activation test is a biomarker for the severity and/or threshold of allergic reactions to milk and peanuts. Conclusion Only a few publications identified possible prognostic indicators of the persistence or severity of FA and outcomes of oral food challenges, indicating that more accessible biomarkers are needed to determine the likelihood of having a severe food allergic reaction. (FA decades Milk eggs anaphylaxis Therefore andor IgEmediated mediated Reviews PubMed SciELO EMBASE Scopus NewcastleOttawa Newcastle Ottawa Scale 1 1398 398 1,39 patients sIgE, , (sIgE) IgG tests foods reaction 139 39 1,3 (sIgE 13 3 1,

ABSTRACT OBJECTIVE: Analyze marketing communication strategies (MCS) of labels of food products consumed by children under 5 years of age from the Brazilian National Health System (SUS) in the city of Rio de Janeiro. METHODS: In total, 390 labels of ultra-processed foods and industrialized baby foods were analyzed. The products were organized by similarity into 24 groups. Photographs of labels from each group were analyzed to identify the MCS, which were categorized into “presence of characters and/or celebrities,” “emotional appeal,” “freebies offering,” “health appeal,” “sensory stimulation,” “brand or slogan use,” “promotional price,” “advertisement under advertisement,” and “sustainability appeal.” The percentage frequency of labels according to the number of MCS per label; the total and average frequency of MCS according to the food group; the frequency of MCS type according to the food group; and communication resources by type of MCS were computed. RESULTS: 1 to 19 strategies were found per label and an average of 7.2 MCS per label, totaling 2,792 occurrences. The MCS “sensory stimulation,” “health appeal,” “brand or slogan use,” and “advertisement under advertising” were observed in all food groups. “Freebies offering” and “promotional price” were observed in eight and six food groups, respectively. In food groups of bread; dairy products; and sweets, candies, and goodies, all nine types of MCS included in the study were identified. The groups that presented fewer types of MCS (n=5) were: peanuts, instant noodles, and margarines. Of the total MCS identified on the labels, the most frequent were “sensory stimulation” (29.4%) and “health appeal” (18.2%); and the least frequent were “freebies offering” (0.8%) and “promotional price” (0.4%). The “emotional appeal” strategy presented the highest diversity of communication resources. CONCLUSION: Rigorous regulatory measures are required to protect consumers from massive exposure to MCS on food labels. OBJECTIVE (MCS SUS (SUS Janeiro METHODS 39 ultraprocessed ultra processed 2 presence andor celebrities, celebrities emotional appeal, appeal freebies offering, offering health sensory stimulation, stimulation brand use, use promotional price, price advertisement advertisement, sustainability appeal. computed RESULTS 72 7 7. 2792 792 2,79 occurrences advertising Freebies respectively bread sweets candies goodies n=5 n5 n (n=5 peanuts noodles margarines 29.4% 294 29 4 (29.4% 18.2% 182 18 (18.2%) 0.8% 08 0 8 (0.8% 0.4%. 04 0.4% . (0.4%) CONCLUSION 3 279 79 2,7 n= (n= 29.4 (29.4 18.2 (18.2% 0.8 (0.8 0.4 (0.4% 27 2, (n 29. (29. 18. (18.2 0. (0. (0.4 (29 (18. (0 (2 (18 ( (1

RESUMO OBJETIVO: Analisar estratégias de comunicação mercadológica (ECM) presentes em rótulos de produtos efetivamente consumidos por crianças menores de 5 anos usuárias do Sistema Único de Saúde na cidade do Rio de Janeiro. MÉTODOS: Foram analisados 390 rótulos de alimentos ultraprocessados e papas infantis industrializadas. Os produtos foram organizados por similaridade em 24 grupos. Realizou-se a análise das fotografias dos rótulos de cada grupo para a identificação das ECM, que foram categorizadas em: “presença de personagens e/ou celebridades”, “apelo emocional”, “oferta de brindes”, “apelo à saúde”, “estímulos aos sentidos”, “uso da marca ou slogan”, “preço promocional”, “propaganda sob propaganda” e “apelo à sustentabilidade”. Foram computadas: frequência percentual de rótulos segundo número de ECM por rótulo; frequência total e média de ECM segundo grupo de alimentos; frequência do tipo de ECM segundo grupo de alimentos; e recursos comunicacionais por tipo de ECM. RESULTADOS: Constataram-se de uma a 19 estratégias por rótulo e média de 7,2 ECM por rótulo, totalizando 2.792 ocorrências. As ECM “estímulo aos sentidos”, “apelo à saúde”, “uso da marca ou slogan” e “propaganda sob propaganda” foram observadas em todos os grupos de alimentos. Já “oferta de brindes” e “preço promocional” apareceram em oito e seis grupos de alimentos, respectivamente. Nos grupos pães, lácteos e doces, balas e guloseimas, foram identificados os nove tipos de ECM incluídos no estudo. Os grupos que apresentaram menos tipos de ECM (n = 5) foram: amendoins, macarrões instantâneos e margarinas. Do total de ECM identificadas nos rótulos, as mais recorrentes foram “estímulo aos sentidos” (29,4%) e “apelo à saúde” (18,2%); e as menos frequentes foram “oferta de brindes” (0,8%) e “preço promocional” (0,4%). A ECM “apelo emocional” apresentou a maior diversidade de recursos comunicacionais. CONCLUSÃO: São necessárias medidas regulatórias rigorosas que protejam o consumidor da massiva exposição às ECM em rótulos de alimentos. OBJETIVO (ECM Janeiro MÉTODOS 39 industrializadas 2 Realizouse Realizou se presença eou celebridades, celebridades , celebridades” apelo emocional, emocional oferta brindes, brindes saúde, saúde estímulos sentidos, sentidos uso slogan, slogan preço promocional, promocional propaganda sustentabilidade. sustentabilidade . sustentabilidade” computadas RESULTADOS Constataramse Constataram 1 72 7 7, 2792 792 2.79 ocorrências estímulo respectivamente pães doces guloseimas estudo n amendoins margarinas 29,4% 294 29 4 (29,4% 18,2% 182 18 (18,2%) 0,8% 08 0 8 (0,8% 0,4%. 04 0,4% (0,4%) CONCLUSÃO 3 279 79 2.7 29,4 (29,4 18,2 (18,2% 0,8 (0,8 0,4 (0,4% 27 2. 29, (29, 18, (18,2 0, (0, (0,4 (29 (18, (0 (2 (18 ( (1