ABSTRACT: This research aimed to understand the subject regarding the 2030 Agenda Sustainable Development Goals and food production through literature reviews covering the timespan from 2001 to 2021. Methodologically, this paper is framed as a literature review and uses the Scopus platform to get to the database, selecting 243 papers. The results pointed out that the United States presented the highest number of published documents (126). When it comes to the origin of affiliation, the universities located in the Netherlands (University of Wageningen) and Canada (University of Guelph) present together the highest number of published documents (24). Among the keywords, the most frequent are food safety, followed by the food supply, sustainability, and climate change. Finally, regarding the main subjects tackled during the analyzed time period, it was verified that the issues concerning public policies, land use, and food safety were discussed throughout the entire timespan. In turn, the most recent period, mainly covering the articles published from the year 2021 on, inserts into the discussion agenda the aspects of Covid-19, the pandemic, and its impacts, especially influenced by the setting experienced worldwide. At the same time, other subjects less discussed took the spotlight, also emerging from the Covid-19 pandemic, such as digital agriculture and digital technology, which began to have major relevance. At last, it is possible to infer that reaching sustainable development goals is even more challenging under a pandemic context experienced by all the countries from 2020 to the present day. ABSTRACT 203 200 Methodologically database 24 papers 126. 126 . (126) affiliation University Wageningen Guelph 24. (24) keywords supply sustainability change Finally period policies use turn 202 on Covid19, Covid19 Covid 19, 19 impacts worldwide spotlight Covid-1 technology relevance last day 20 2 12 (126 (24 Covid1 1 Covid- (12 (2 (1 (

RESUMO: O objetivo deste trabalho foi compreender a temática em torno dos Objetivos do Desenvolvimento Sustentável Agenda 2030 e a produção de alimentos através de uma análise bibliográfica compreendendo o período de 2001 a 2021. Metodologicamente o estudo se enquadra como uma revisão bibliográfica e se utilizou a plataforma Scopus para obtenção da base de dados, sendo selecionados 243 artigos. Os resultados apontaram que os Estados Unidos apresentaram o maior número de documentos publicados (126). Em relação a afiliação de origem, universidades localizadas na Holanda (Universidy de Wageningen) e Canadá (Universidy de Guelph) são as que apresentam juntas o maior número de documentos publicados (24). Entre as palavras-chaves a que mais aparece é segurança alimentar, seguida de fornecimento de alimentos, sustentabilidade e mudanças climáticas. Finalmente, no que diz respeito às principais temáticas abordadas durante o período analisado, constatou-se que questões relacionadas a políticas públicas, uso da terra e segurança alimentar foram discutidas ao longo de todo período analisado. Já no período mais recente, que compreende sobretudo os artigos publicados a partir do ano de 2021, insere-se na agenda de discussão, influenciada pelo cenário vivenciado no mundo todo, aspectos relacionados à pandemia, Covid 19 e seus impactos. Ao mesmo tempo, ganharam relevância temas ainda pouco discutidos, os quais emergem também a partir da pandemia do Covid 19, dentre eles a agricultura digital e tecnologias digitais, que passaram a ter grande relevância. Finalmente, é possível inferir que alcançar os objetivos do desenvolvimento sustentável se tornou ainda mais desafiador em um contexto de Pandemia, vivenciado em todos os países do mundo no período de 2020 aos dias atuais. RESUMO 203 200 2021 dados 24 126. 126 . (126) origem Universidy Wageningen Guelph 24. (24) palavraschaves palavras chaves climáticas Finalmente analisado constatouse constatou públicas recente inserese insere discussão 1 impactos tempo discutidos digitais Pandemia 202 atuais 20 2 12 (126 (24 (12 (2 (1 (

ABSTRACT The term 'stealthing' refers to non-consensual condom removal during sexual intercourse. This practice carried out against the will of the person who agreed to engage in sexual intercourse under specific modalities, such as the use of a condom, which, in turn, translates to a disruption in the consent. This article argues that in Chile the deficient regulation of sexual and reproductive rights wouldn't allow the bill about the non-consensual removal of the condom in a sexual intercourse respond to this phenomenon and its normalization. To develop this idea, has been reviewed the legal and jurisprudential situation of countries such as the United Kingdom, New Zealand, Germany, Netherlands, United States, Costa Rica and Colombia, as well as the pronouncement of international law on the sexual and reproductive rights. The article concludes that the lack of regulations on these rights encourages the normalization of sexually abusive behavior.

RESUMEN El término stealthing designa al retiro no consentido del preservativo durante una relación sexual. Esta práctica es realizada ante la negativa o con el desconocimiento de quien consintió tener relaciones sexuales bajo condiciones específicas, como el uso de condón, lo cual genera un quiebre en el consentimiento. Este artículo argumenta que en Chile la deficiente regulación de los derechos sexuales y reproductivos no permitiría que el proyecto de ley que busca sancionar la remoción no consentida del condón en una relación sexual dé respuesta a este fenómeno y su normalización. Para desarrollar esta idea se ha revisado tanto la situación normativa como la jurisprudencial de países como Reino Unido, Nueva Zelanda, Alemania, Países Bajos, Estados Unidos, Costa Rica y Colombia, al igual que el pronunciamiento del derecho internacional sobre los derechos sexuales y reproductivos. El artículo concluye que la falta de normativa sobre estos derechos insta a la normalización de conductas atentatorias contra la sexualidad y la reproducción.

Abstract Introduction The prevalence of otitis media (OM) is substantial all over the world. Epidemiological data related to the economic burden of OM globally is minimal. The present systematic review was undertaken to estimate the economic burden of this disease in various parts of the world. Objectives An extensive literature search was done using PRISMA guidelines to identify relevant studies that estimated the economic burden of OM in monetary terms. The databases searched were PubMed Central, Ovid, and Embase. The cost estimation was done for one specific year and then compared considering the inflation rate. Data Synthesis The literature search led to the inclusion of 10 studies. The studies evaluated direct and indirect costs in monetary terms. Direct costs (health system and patient perspective) ranged from USD (United States Dollar) 122.64 (Netherlands) to USD 633.6 (USA) per episode of OM. Looking at only the patient perspective, the costs ranged from USD 19.32 (Oman) to USD 80.5 (Saudi Arabia). The total costs (direct and indirect) ranged from USD 232.7 to USD 977 (UK) per episode of OM. The economic burden per year was highest in the USA (USD 5 billion). The incidence of OM episodes was found more in children < 5 years old. Introduction of pneumococcal conjugate vaccines decreased the incidence in children and now the prevalence in adults is of concern. Conclusion The economic burden of OM is relatively high globally and addressing this public health burden is important. Approaches for the prevention, diagnosis, and treatment should be undertaken by the health system to alleviate this disease burden. (OM world minimal terms Central Ovid Embase rate 1 perspective United Dollar 12264 122 64 122.6 Netherlands (Netherlands 6336 633 6 633. (USA 1932 19 32 19.3 Oman (Oman 805 80 80. Saudi Arabia. Arabia . Arabia) 2327 232 7 232. 97 UK (UK billion. billion billion) old concern important prevention diagnosis 1226 12 122. 63 193 3 19. 8 23 9 2

ABSTRACT With inflation on the rise in recent years, there has been an important debate on price increases and their impact on different areas of the economy, politics, and society. This article analyzes different methods of statistical measurement of price increases at different stages of production and consumption, as well as inflation. It exem-plifies, in particular, with cases from the United States and the Netherlands. It also points out some shortcomings in the methods applied, especially in neoclassical macroeconomic models.

RESUMEN Con la inflación en auge en los últimos años, se ha generado un importante debate sobre el aumento de precios y su impacto en los distintos ámbitos de la economía, la política y la sociedad. Este artículo hace un análisis sobre distintos métodos de medición estadística del ascenso de los precios en las diferentes etapas de producción y consumo, y la inflación. Ejemplifica, en particular, con casos de los Estados Unidos y los Países Bajos. También señala algunas deficiencias en los métodos aplicados, sobre todo, en los modelos macroeconómicos neoclásicos.

Resumen: Henry van de Velde es uno de los arquitectos más polifacéticos de la historia de la arquitectura del siglo pasado, tanto por su obra como por la versatilidad de las estrategias que emplea a lo largo de su trayectoria. El autor belga se acercó a multitud de disciplinas artísticas, dejándose influenciar por ideas del Arts & Crafts de William Morris, vinculándose a los inicios del Art Nouveau o involucrándose en el Deutscher Werkbund hasta 1914. El desarrollo de esta actitud multidisciplinar, síntoma de su evolución creativa, vive uno de los episodios más intensos durante su vinculación laboral con el matrimonio de coleccionistas de arte moderno Kröller-Müller en los Países Bajos. La presente investigación desgrana el legado gráfico y arquitectónico de Henry van de Velde al servicio de los Kröller-Müller, desde los primeros bocetos en los años 20 hasta la ejecución del museo de 1936-57. Un verdadero ejemplo de materialización de sueño arquitectónico.

Abstract: Henry van de Velde is one of the most multifaceted architects in the history of architecture in the last century, both in terms of his work and the versatility of the strategies he employed throughout his career. The Belgian architect drew close to a multitude of artistic disciplines, allowing himself to be influenced by the ideas of William Morris's Arts & Crafts, linking himself to the beginnings of Art Nouveau or becoming involved in the Deutscher Werkbund until 1914. The development of this multidisciplinary attitude, a symptom of his creative evolution, experienced one of its most intense episodes during his working relationship with the Kröller-Müller couple of modern art collectors in the Netherlands. This research unravels Henry van de Velde's graphic and architectural legacy in the service of the Kröller-Müller family, from the first sketches in the 1920s to the execution of the museum in 1936-57. A true example of the realisation of an architectural dream.

Resumen Objetivo: ChatGPT (transformador preentrenado generativo de Chatbot) es un sistema generativo preentrenado basado en la arquitectura GPT-3.5, que fue presentado en noviembre de 2022. Este simula una conversación habitual al responder preguntas y tiene gran lugar en la redacción científica. Nuestro objetivo es identificar y analizar la tendencia de las publicaciones sobre ChatGPT en el ámbito de la medicina a nivel mundial desde su lanzamiento. Método: Se incluyeron artículos desde su origen (2022) hasta abril de 2023 mediante las bases de datos Medline y Embase. Evaluamos el factor de impacto (FI) 2021, el Journal Citation Reports (JCR) por medio de Clarivate Analytics y el índice H por medio de SCImago. Realizamos un análisis por mapeo mediante VOSViewer y se graficaron los datos. Resultados: Se obtuvieron 533 artículos de los cuales al ser depurados fueron elegidos 309. La revista Cureus y medRxiv encabezan el top diez con la mayor cantidad de publicaciones. Tan solo tres revistas de urología tienen sus publicaciones relacionadas con el tema. EE.UU., Inglaterra y Países Bajos son líder y el tipo de publicación más frecuente fueron los artículos originales (22,7%). Conclusiones: ChatGPT es el inicio de una nueva era que nos facilitará algunos procesos en el área de la salud. La literatura médica se encuentra investigando en busca de sus utilidades y desventajas. Es necesario conocer los alcances y limitaciones de este tipo de chatbot para aplicarlo en el panorama médico sin que sobrepase los márgenes de la ética.

Abstract Objective: ChatGPT is an AI (artificial intelligence) pre-trained based in GPT-3.5 architecture, which was launched in November 2022. This AI simulates an every-day chat, responding to different sorts of topics and its widely used in scientific production. Our objective is to identify and analyze the publication trends about ChatGPT and its uses in medicine around the world. Method: Published article since ChatGPT launch (2022) until April 2023 were included. Medline and Embase data bases were used to run the search. We evaluated the impact factor (IF) 2021, the Journal Citation Reports (JCR) using Clarivate Analytics and H index using SCImago. We also used map analysis through VOSViewer and graphed the data. Results: The search gathered 533 articles which were reduced and picked 309 of them. Cureus journal and medRxiv lead the most publications top ten. Only three of the urology-related journals have publications regarding ChatGPT. USA, England and Netherlands are the countries with most scientific productions and the most frequent type of article were original articles (22.7%). Conclusion: ChatGPT may be the beginning of a new worldwide era which will ease-up several processes in healthcare. Different medical sciences are investigating around this tool looking for opportunities and disadvantages. It is fundamental to know the uses and limitations with this type of chatbot for applying it in healthcare without trespassing ethical boundaries.

Resumen La violencia de pareja íntima es una problemática que afecta el desarrollo de la que es considerada el seno de la formación del individuo, esto es, la familia. Es por ello que la presente revisión rápida se centra en buscar estudios empíricos que prueben la validez y confiabilidad de una herramienta de predicción del riesgo de violencia íntima, como la Evaluación de Riesgo de asalto Doméstico de Ontario (ODARA), así como en buscar evidencia empírica de efectividad de un programa que brinde a las víctimas de violencia íntima herramientas para la prevención de ese tipo de violencia, como el Programa de Apoyo Comunitario (CAP). De los 221 documentos encontrados, 14 fueron incluidos en la presente revisión. En los estudios se pudo establecer que el ODARA es una herramienta actuarial ‒que cuenta con evidencia empírica en países como Canadá, Suiza, Australia, Estados Unidos, Holanda y Reino Unido‒, que va desde AUC=0,643 hasta AUC=0.744. El CAP cuenta con resultados estadísticamente significativos en la adquisición de recursos por parte de las víctimas de violencia íntima en áreas como satisfacción con el apoyo social, efectividad en la obtención de recursos, acceso a recursos comunitarios y calidad de vida. Tanto el ODARA como el CAP cuentan con evidencia empírica que permite establecerlos como adecuados para la predicción y prevención de reincidencia de la violencia de pareja íntima.

Abstract Intimate partner violence is a problem that affects the development of what is considered the core of the formation of the individual, that is, the family. That is why this rapid review focuses on seeking empirical studies that test the validity and reliability of an intimate violence risk prediction tool such as the Ontario Domestic Assault Risk Assessment (ODARA), and empirical evidence of effectiveness of a program that provides victims of intimate violence with tools to prevent this type of violence, such as the Community Support Program (CAP). Of the 221 documents found, 14 were included in this review. In the studies, it was established that the ODARA is an actuarial tool that has empirical evidence in countries such as Canada, Switzerland, Australia, the United States, the Netherlands, and the United Kingdom, ranging from AUC = 0.643 to AUC = 0.744. The CAP has statistically significant results in the acquisition of resources by victims of intimate violence in areas such as satisfaction with social support, effectiveness in obtaining resources, access to community resources and quality of life. Both the ODARA and the CAP have empirical evidence that allows them to be established as adequate for the prediction and prevention of recidivism of intimate partner violence.

Resumen La pequeña agricultura del secano de Chile Central se enfrenta hoy a diversas limitaciones como son la escasez o variabilidad de regímenes de lluvias anuales, la influencia del cambio climático global y lejanía de los centros de desarrollo. La implementación de programas para el desarrollo agrícola requiere de un adecuado diagnóstico y evaluación de la sostenibilidad de los sistemas agrícolas, lo que es posible realizar usando una diversidad de índices. Este estudio analizó la sostenibilidad de la pequeña agricultura de secano de la Región de Valparaíso en Chile Central a través del marco SAFA Smallholders de la FAO. Esta herramienta ha sido validada en diferentes contextos, incluyendo indicadores en dimensiones social, ambiental, económico y de gobernanza. En particular, se evaluó la sostenibilidad de 30 predios representativos de la zona en cuanto a la diversidad de cultivos, enfoque de producción (convencional vs. agroecológico) y el acceso a agua para riego. Al no existir antecedentes previos de este tipo de evaluaciones mediante la herramienta SAFA en el país, este estudio podría considerarse como exploratorio. Los resultados muestran un nivel de sostenibilidad intermedio con un valor promedio de 60% en una escala de 1-100%. Los predios con mayor diversidad de cultivos y prácticas agroecológicas revelaron más altos niveles de sostenibilidad que aquellos con enfoque en monocultivo y prácticas convencionales. Los resultados sugieren fomentar prácticas agroecológicas acorde a la precariedad de recursos hídricos disponibles; reforzar los programas e iniciativas que contribuyan a la participación de los productores en sus organizaciones gremiales e inversiones comunitarias de su territorio; mejorar su liquidez con el acceso a diferentes fuentes de financiamiento; y ampliar a un mayor público las capacitaciones técnicas y de gestión.

Abstract Small-scale agriculture in the drylands of Central Chile is facing several challenges, such as scarcity or variability of annual rainfall regimes, the impact of global climate change, and distance from development centers. The implementation of programs for agricultural development requires an adequate diagnosis and assessment of the sustainability of agricultural systems, which can be conducted using a diversity of indices. This study analyzed the sustainability of small-scale dryland agriculture in the Valparaíso Region in Central Chile through the FAO SAFA Smallholders framework. This tool has been validated in different contexts, including indicators in social, environmental, economic and governance dimensions. In particular, the sustainability of 30 representative farms in the study area was evaluated in terms of crop diversity, production approach (conventional vs. agroecological) and access to water for irrigation. As there is no previous history of the use of the SAFA tool in this type of evaluations in the country, this study could be considered exploratory. The results show an intermediate level of sustainability with an average value of 60% on a scale of 1-100%. Farms with greater diversity of crops and agroecological practices revealed higher levels of sustainability than those with a focus on monoculture and conventional practices. The results highlight the importance of promoting agroecological practices according to the precariousness of available water resources; reinforcing programs and initiatives that contribute to the participation of farmers in their union organizations and community investments in their territory; improving farmers’ liquidity through the access to different financing sources; and expanding technical and management training to a larger audience.

Abstract Purpose: This study aims to examine foreign direct investment (FDI) factors and develops a rational framework for FDI inflow in Western European countries such as France, Germany, the Netherlands, Switzerland, Belgium and Austria. Design/methodology/approach: Data for this study were collected from the World development indicators (WDI) database from 1995 to 2018. Factors such as economic growth, pollution, trade, domestic capital investment, gross value-added and the financial stability of the country that influence FDI decisions were selected through empirical literature. A framework was developed using interpretable machine learning (IML), decision trees and three-stage least squares simultaneous equation methods for FDI inflow in Western Europe. Findings: The findings of this study show that there is a difference between the most important and trusted factors for FDI inflow. Additionally, this study shows that machine learning (ML) models can perform better than conventional linear regression models. Research limitations/implications: This research has several limitations. Ideally, classification accuracies should be higher, and the current scope of this research is limited to examining the performance of FDI determinants within Western Europe. Practical implications: Through this framework, the national government can understand how investors make their capital allocation decisions in their country. The framework developed in this study can help policymakers better understand the rationality of FDI inflows. Originality/value: An IML framework has not been developed in prior studies to analyze FDI inflows. Additionally, the author demonstrates the applicability of the IML framework for estimating FDI inflows in Western Europe.

Resumo Mar González é psicóloga e foi uma das pioneiras nos estudos sobre a homoparentalidade na Espanha. Suas pesquisas, a partir dos anos 2000, tiveram papel relevante no debate parlamentar no país, que culminou com a aprovação do casamento homossexual em 2015. A Espanha, um país de maioria católica que havia deixado a ditadura franquista três décadas antes, foi o terceiro país no mundo, depois de Bélgica e Holanda, a reconhecer o direito de união da população homossexual. Seus estudos versam sobre famílias não convencionais, diversidade familiar, desenvolvimento infantil e familiar e sua relação com educação e saúde. Nossa conversa tratou do tema da homoparentalidade, do estabelecimento dos direitos de filiação para esse grupo social, dos estudos sobre essas configurações familiares e as principais implicações da homoparentalidade para a saúde.

Abstract Mar González is a psychologist and one of the pioneers in studies on LGB-parent families in Spain. Her research work from the 2000s onwards played an essential role in the parliamentary debate in the country, which culminated in the approval of same-sex marriage in 2005. Spain, a Catholic-majority country that had left the Franco dictatorship three decades earlier, was the third country in the world, after Belgium and Netherlands, to recognize the right of gay and lesbian people to unite. Her studies address unconventional families, family diversity, child and family development, and their relationship with education and health. Our conversation addressed LBG parenthood, the establishment of filiation rights for this social group, studies on these family configurations, and leading LGB parenthood health implications.

Abstract Mar González is a psychologist and one of the pioneers in studies on LGB-parent families in Spain. Her research work from the 2000s onwards played an essential role in the parliamentary debate in the country, which culminated in the approval of same-sex marriage in 2005. Spain, a Catholic-majority country that had left the Franco dictatorship three decades earlier, was the third country in the world, after Belgium and Netherlands, to recognize the right of gay and lesbian people to unite. Her studies address unconventional families, family diversity, child and family development, and their relationship with education and health. Our conversation addressed LBG parenthood, the establishment of filiation rights for this social group, studies on these family configurations, and leading LGB parenthood health implications. LGBparent parent Spain s samesex same sex 2005 Catholicmajority Catholic majority earlier world Netherlands unite diversity development group configurations implications 200 20 2

Resumo Mar González é psicóloga e foi uma das pioneiras nos estudos sobre a homoparentalidade na Espanha. Suas pesquisas, a partir dos anos 2000, tiveram papel relevante no debate parlamentar no país, que culminou com a aprovação do casamento homossexual em 2015. A Espanha, um país de maioria católica que havia deixado a ditadura franquista três décadas antes, foi o terceiro país no mundo, depois de Bélgica e Holanda, a reconhecer o direito de união da população homossexual. Seus estudos versam sobre famílias não convencionais, diversidade familiar, desenvolvimento infantil e familiar e sua relação com educação e saúde. Nossa conversa tratou do tema da homoparentalidade, do estabelecimento dos direitos de filiação para esse grupo social, dos estudos sobre essas configurações familiares e as principais implicações da homoparentalidade para a saúde. Espanha pesquisas 2000 2015 antes mundo Holanda convencionais saúde social 200 201 20 2

Abstract Introduction The Iowa-Netherlands Comparison Orientation Measure (INCOM) was developed to measure individual differences in social comparison orientation and has been widely used in research and various different settings. Objectives The aim of this study was to adapt the online version of the INCOM and to evaluate its psychometric parameters when applied to a Brazilian population of university students. Methods The procedures were divided into two steps: step 1 – cross-cultural adaptation and analysis of content validity, and step 2 – assessment of psychometric characteristics. Step 1 comprised the processes of translation, evaluation by an expert committee, evaluation by the target population, and back-translation. For step 2, 1,065 university students were recruited and then factor analysis, analysis of reliability, and analysis of validity based on external measures were performed. Results The adaptation process yielded satisfactory results, including good indicators of content validity. Exploratory factor analysis revealed a two-dimensional structure and adequate factor loadings, except for item 11, which was excluded from the final version. Additionally, the final version of the scale had adequate fit indices (χ2 = 148.45, degrees of freedom [df] = 26; p < 0.001; root mean square error of approximation [RMSEA] = 0.06; comparative fit index [CFI] = 0.99; and Tucker-Lewis index [TLI] = 0.98). Evidence of reliability (Cronbach’s alpha = 0.83) was observed and there were positive correlations with negative affect (r = 0.36) and negative correlations with positive affect and self-esteem (r = -0.15; r = -0.41, respectively). Conclusion The Brazilian version of the INCOM presents satisfactory psychometric parameters and can thus be used to measure social comparison orientation. IowaNetherlands Iowa Netherlands (INCOM settings steps crosscultural cross cultural characteristics translation committee backtranslation. backtranslation back translation. back-translation 1065 065 1,06 performed results twodimensional dimensional loadings 11 Additionally χ2 χ (χ 14845 148 45 148.45 df [df 26 0.001 0001 0 001 RMSEA [RMSEA 0.06 006 06 CFI [CFI 0.99 099 99 TuckerLewis Tucker Lewis TLI [TLI 0.98. 098 0.98 . 98 0.98) Cronbachs Cronbach s 0.83 083 83 0.36 036 36 selfesteem self esteem 0.15 015 15 -0.15 0.41, 041 41 -0.41 respectively. respectively respectively) 106 1,0 1484 14 4 148.4 0.00 000 00 0.0 0.9 09 9 0.8 08 8 0.3 03 3 0.1 01 -0.1 0.41 04 -0.4 10 1, 148. 0. -0. 0.4 -0 -

Resumo Introdução: O caráter persistente de elevada endemicidade da hanseníase em áreas específicas no Brasil segue um desafio. O reconhecimento de redes de convívio domiciliar (RCD) de casos de hanseníase, com base no entendimento sobre riscos e vulnerabilidades ampliadas, é estratégico para controle. Objetivo: Analisar a ocorrência da hanseníase em diferentes gerações, a densidade de casos e os perfis sociodemográfico e econômico vinculados a redes de convívio domiciliar (RCD) com sobreposição da doença em municípios do Norte e Nordeste do Brasil. Método: Estudo transversal, com dados primários de casos de hanseníase que fazem parte de uma RCD com no mínimo dois casos da doença. Empregou-se regressão logística para estimar razão de chances (OR) com intervalos de 95% de confiança (IC95%). Resultados: Duzentos e trinta e três (233) casos de hanseníase foram abordados, vinculados a 137 RCD. Em 53,2% (n=171) dos casos a doença atingiu duas gerações e em 20,2% (n=47), três gerações. Verificou-se maior chance de acometimento de duas ou mais gerações com diagnóstico apenas entre consanguíneos na RCD (OR-Ajustado= 4,35, IC95% 2,15–8,81) e diagnóstico de outros casos antes e depois (OR-Ajustado =8,51, IC95% 3,52–20,60). A maioria pertence a RCD com mais de três casos, com média de 4,1 casos por RCD (desvio padrão=3,3). Conclusões: O reconhecimento da sobreposição de casos de hanseníase em uma RCD, o número de gerações acometidas e a densidade de casos podem ser utilizados como indicadores-sentinela da situação epidemiológica e da capacidade operacional para a vigilância da hanseníase. Introdução desafio (RCD ampliadas controle Objetivo Método transversal Empregouse Empregou se OR (OR 95 IC95%. IC95 IC . (IC95%) Resultados 233 (233 abordados 13 532 53 2 53,2 n=171 n171 n 171 (n=171 202 20 20,2 n=47, n47 n=47 , 47 (n=47) Verificouse Verificou ORAjustado= ORAjustado Ajustado= Ajustado 435 4 35 4,35 2,15–8,81 215881 15 8 81 851 51 =8,51 3,52–20,60. 3522060 3,52–20,60 3 52 60 3,52–20,60) 41 1 4, desvio padrão=3,3. padrão33 padrão padrão=3,3 padrão=3,3) Conclusões indicadoressentinela indicadores sentinela 9 IC9 (IC95% 23 (23 5 53, n=17 n17 17 (n=17 20, n4 n=4 (n=47 43 4,3 2,15–8,8 21588 85 =8,5 352206 3,52–20,6 6 padrão3 padrão=3, (IC95 (2 n=1 n1 (n=1 n= (n=4 2,15–8, 2158 =8, 35220 3,52–20, padrão=3 (IC9 ( (n= 2,15–8 215 =8 3522 3,52–20 padrão= (IC (n 2,15– 21 = 352 3,52–2 2,15 3,52– 2,1 3,52 2, 3,5 3,

Abstract Background: The persistent high endemicity of leprosy in certain areas of Brazil remains a challenge. Identifying household contact networks (HCN) of leprosy cases, based on an understanding of expanded risks and vulnerabilities, is strategic for control. Objective: To analyze the occurrence of leprosy in different generations, the density of cases, and the sociodemographic and economic profiles linked to household contact networks (HCN) with overlapping disease in municipalities in the North and Northeast of Brazil. Method: Cross-sectional study with primary data from leprosy cases that are part of an HCN with at least two cases of the disease. Logistic regression was used to estimate odds ratios (OR) with 95% confidence intervals (95%CI). Results: Two hundred and thirty-three (233) leprosy cases were addressed, linked to 137 HCN. In 53.2% (n=171) of the cases, the disease affected two generations, and in 20.2% (n=47), three generations. There was a higher chance of affecting two or more generations with diagnosis only among consanguineous individuals in the HCN (adjusted OR=4.35, CI95% 2.15–8.81) and diagnosis of other cases before and after (adjusted OR=8.51, CI95% 3.52–20.60). The majority belonged to HCN with more than three cases, with an average of 4.1 cases per HCN (standard deviation=3.3). Conclusions: The recognition of the overlap of leprosy cases in an HCN, the number of affected generations, and the case density can be used as sentinel indicators of the epidemiological situation and the operational capacity for leprosy surveillance. Background challenge (HCN vulnerabilities control Objective Method Crosssectional Cross sectional OR (OR 95 95%CI. 95CI CI 95%CI . (95%CI) Results thirtythree thirty 233 (233 addressed 13 532 53 2 53.2 n=171 n171 n 171 (n=171 202 20 20.2 n=47, n47 n=47 , 47 (n=47) adjusted OR435 4 35 OR=4.35 CI95 2.15–8.81 215881 15 8 81 OR851 51 OR=8.51 3.52–20.60. 3522060 3.52–20.60 3 52 60 3.52–20.60) 41 1 4. standard deviation=3.3. deviation33 deviation deviation=3.3 deviation=3.3) Conclusions surveillance 9 (95%CI 23 (23 5 53. n=17 n17 17 (n=17 20. n4 n=4 (n=47 OR43 OR=4.3 CI9 2.15–8.8 21588 OR85 OR=8.5 352206 3.52–20.6 6 deviation3 deviation=3. (2 n=1 n1 (n=1 n= (n=4 OR4 OR=4. 2.15–8. 2158 OR8 OR=8. 35220 3.52–20. deviation=3 ( (n= OR=4 2.15–8 215 OR=8 3522 3.52–20 deviation= (n OR= 2.15– 21 352 3.52–2 2.15 3.52– 2.1 3.52 2. 3.5 3.

ABSTRACT Chlorophyll fluorescence analysis is a method that has been widely disseminated among researchers for ensuring fast, accurate and non-destructive results. Thus, this study aimed to assess the chlorophyll a fluorescence of pepper seedlings grown from seeds that were unprimed, hydroprimed and primed with 24-EpiBL at 10-8 M after induction of salt stress at three concentrations (0.0, -0.2 and -0.4 MPa). To carry out the experiment, the Seed Reporter Camera Spectral & Color Imaging System (PhenoVation Life Sciences, Wageningen, Netherlands) was used. Three lots of seeds of the pepper cultivar ‘Biquinho’ were used. Chlorophyll fluorescence in the seedlings was evaluated on the seventh day after the seeds were subjected to different levels of salt stress. The chlorophyll fluorescence images obtained were analyzed by the CFTI - Analysis software (version 4.5). Through the data obtained it was possible to verify that, in general, there was an increase in chlorophyll a fluorescence in seedlings grown from seeds primed with 24-EpiBL. In short, the chlorophyll fluorescence technique proved to be viable and efficient, in addition to being a practical tool that can be used to support the analysis of the quality of pepper seedlings, whether or not subjected to saline stress conditions. fast nondestructive non destructive results Thus unprimed 24EpiBL EpiBL 24 108 10 8 10- 0.0, 00 0 (0.0 0.2 02 2 -0. 0.4 04 4 MPa. MPa . MPa) experiment PhenoVation Sciences Wageningen Netherlands ‘Biquinho Biquinho version 4.5. 45 4.5 5 4.5) general 24EpiBL. EpiBL. short efficient conditions 1 0.0 (0. 0. -0 4. (0 (