Abstract The article presents the conception of an acoustic project for a new opera house, called “O Guarani”, to be implemented at the federal capital, Brasília, with about 1000 seats. The main focus of the article is the acoustic conditioning of the opera house. Initially, the basic assumptions from the acoustical point of view that an opera house demands are discussed. The main constraints, such as reverberation time, must take into account both music and speech which is a typical characteristic for a room of this kind. Once the architectural concept and the materials to be used have been defined, a computational simulation is carried out, aiming to determine acoustic quality parameters, such as T20, C80 and D50, for receivers distributed in the audience. These parameters proved to be satisfactory for the intended use of the proposed theater. An auralization is then conducted. This is prepared for an aria of the opera “Don Giovanni”, by Mozart, from an anechoic recording of a soprano, interpreting D. Elvira, and ten accompanying musical instruments. The result of the auralization - available at a link - seems to show the good sound quality obtained by the proposed acoustic project. O Guarani, Guarani , Guarani” capital Brasília 100 seats Initially discussed constraints time kind defined out T20 T C C8 D50 D audience theater conducted Don Giovanni, Giovanni Giovanni” Mozart soprano Elvira instruments 10 T2 D5 1

Resumo O artigo apresenta a concepção de um projeto acústico para uma nova casa de ópera, denominada “O Guarani”, a ser implantada na capital federal, Brasília, com cerca de 1000 assentos. O foco principal do artigo é o condicionamento acústico da casa de ópera. São discutidos, inicialmente, os pressupostos básicos do ponto de escuta acústico que uma casa de ópera demanda. Os principais condicionantes, como o tempo de reverberação, devem contemplar tanto a música como a fala, o que é uma característica típica de uma casa do gênero. Definidos os materiais a serem utilizados e a concepção arquitetônica, parte-se, em seguida, para uma simulação computacional acústica, visando a determinação de parâmetros de qualidade acústica, como T 20, C 80 e D 50, para receptores distribuídos na plateia e balcões. Esses parâmetros se mostraram satisfatórios para o uso a que se destina o teatro proposto. Na sequência, é elaborada uma aurilização. Esta é preparada para uma ária da ópera “Don Giovanni”, de Mozart, a partir de uma gravação anecoica de uma soprano, interpretando o personagem D. Elvira, e dez instrumentos musicais acompanhantes. O resultado da aurilização - disponível em um link - parece evidenciar a boa qualidade sonora obtida pelo projeto acústico proposto. Guarani, Guarani , Guarani” federal Brasília 100 assentos discutidos inicialmente demanda condicionantes reverberação fala gênero arquitetônica partese, partese parte se, parte-se seguida acústica 20 8 50 balcões proposto sequência Don Giovanni, Giovanni Giovanni” Mozart soprano Elvira acompanhantes 10 2 5 1

Abstract: In this research, we address the composer classification supervised problem from a Natural Language Processing perspective. Starting from digital symbolic music files, we build two representations: a class representation and other based on MIDI pitches. We use the technique of n-grams to build feature vectors of musical compositions based on their harmonic content. For this, we extract n-grams of size 1 to 4 in harmonic direction, differentiating between all possible subsets of instruments. We populate a term-frequency matrix with the vectors of compositions and we classify by the means of Support Vector Machines (SVM) classifier. Different classification models are evaluated, e.g., using feature filters and varying hyperparameters such as TF-IDF formula, among others. The results obtained show that n-grams based on MIDI pitches perform slightly better than n-grams based on class representation in terms of overall results, but the best result of each one of these representations is identical. Some of our best models reach accuracy results that exceed previous state of the art results based on a well-known dataset composed of string quartets by Haydn and Mozart.

ABSTRACT Luis Tavares revolutionized cardiac surgery, always bringing the most modern instruments and equipment from his travels to England - surgical forceps, scissors, scalpels, etc. He always insisted that he was not just a thoracic surgeon, for his work extended over a wide field and created three important cardiac surgery centers which promoted a great development of cardiology. He carried out the first open heart surgery (atrial septal defect) employing extracorporeal circulation and closure of a ventricular septal defect with deep surface hypothermia of north and northeast Brazil. He promoted an intense scientific exchange program between Recife and England, resulting in significant advances in medicine, and participated directly in the creation of HEMOPE), leading to radical changes and improvements in blood therapy in the whole country. The PROCAPE, inaugurated in 2006, was the result of the cardiac center created by him in early 1970 at Hospital Oswaldo Cruz and can be considered the second largest public-university cardiology center in Brazil. He is thus widely regarded as an outstanding name in medicine in the 20th century and one of the fathers of modern cardiac surgery in Brazil. forceps scissors scalpels etc surgeon atrial Brazil HEMOPE, HEMOPE , HEMOPE) country PROCAPE 2006 197 publicuniversity public university th 200 19 20 1 2

Resumo: Este artigo parte do interesse pela reflexão sobre o ensino de humanidades e tem como objetivo compartilhar uma experiência docente específica. Seu objetivo é expor o caminho intelectual que foi percorrido para compor uma aula de literatura e as reflexões que ela suscitou. Partimos da proposta metodológica de Fernando Lázaro Carreter e Evaristo Correa Calderón em Como se interpreta um texto literário (1968) e das ideias desenvolvidas por Daniel Barenboim em La música despierta el tiempo (2023) para propor uma classe de literatura que incorpore música e verifique como a reflexão musical pode ajudar a ler e despertar a sensibilidade para um texto, seus personagens e o conflito que ele suscita.

Resumen: Este artículo parte del interés por la reflexión sobre la enseñanza de las humanidades y tiene como propósito compartir una experiencia docente concreta. Se parte de la propuesta metodológica de Fernando Lázaro Carreter y Evaristo Correa Calderón en Cómo se interpreta un texto literario (1968) y de las ideas desarrolladas por Daniel Barenboim en La música despierta el tiempo (2023) para plantear una clase de literatura que incorpora la música y comprobar de qué manera la reflexión musical puede ayudar a leer y a despertar la sensibilidad hacia un texto, sus personajes y el conflicto que este plantea.

Abstract: This article is based on interest in reflection on the teaching of the humanities and its purpose is to share a specific teaching. Its purpose is to expose the intellectual path that has been followed to compose a class of literature. We start from the methodological proposal of Fernando Lázaro Carreter and Evaristo Correa Calderón in Cómo se comenta un texto literario (1968) and the ideas developed by Daniel Barenboim in Music Quickens Time (2008) to propose a class of literature that incorporates music and helps to realize how musical reflection can help to read and awaken sensitivity towards a text, its characters and the conflict it raises.

Abstract The performance evaluation of services through instruments is relevant, as it can support thoughts, actions and political approaches to meet a social need. The objective of the article was to develop and validate the Quality and Strengthening of Primary Care Questionnaire (QSPC-Q) for professionals and users based on Starfield attributes and Donabedian pillars. A mixed sequential study was performed to develop the QSPC-Q. The test was applied to 149 doctors and 795 users of basic health units. Psychometric properties was assessed by testing internal consistency using Cronbach’s alpha and exploratory factor analysis. Reproducibility od scale was assessed using intraclass cognitive and test-retest correlation. The final version of the follow-up consisted of 45 items aimed at physicians (Cronbach’s alpha = 0.921) and 33 at users (Cronbach’s alpha = 0.86); the intraclass respiratory capacity was 0.88. An exploratory factor analysis identified 13 factors associated with the pattern components. A short version with 29 items for professionals was also elaborated. Professional QSPC-Q (short and braided versions) and user QSPC-Q were valid. relevant thoughts need QSPCQ QSPC Q (QSPC-Q pillars QSPCQ. Q. 14 79 units Cronbachs Cronbach s testretest retest correlation followup follow up 4 0.921 0921 0 921 3 0.86 086 86 0.86) 088 88 0.88 1 components 2 elaborated versions valid 7 0.92 092 92 0.8 08 8 0.9 09 9 0.

Resumo A avaliação do desempenho dos serviços por meio de instrumentos é relevante, pois pode subsidiar pensamentos, ações e abordagens políticas para atender a uma necessidade social. O objetivo do artigo foi desenvolver e validar o Questionário de Qualidade e Fortalecimento da Atenção Primária (QSPC-Q) para profissionais e usuários com base nos atributos Starfield e nos pilares donabedianos. Um estudo sequencial misto foi realizado para desenvolver o QSPC-Q. O teste foi aplicado em 149 médicos e 795 usuários de unidades básicas de saúde. As propriedades psicométricas foram avaliadas testando a consistência interna usando o alfa de Cronbach e a análise fatorial exploratória. A reprodutibilidade da escala foi avaliada por meio da correlação cognitiva intraclasse e teste-reteste. A versão final do questionário foi composta por 45 itens direcionados a médicos (alfa de Cronbach = 0,921) e 33 a usuários (alfa de Cronbach = 0,86); o coeficiente de correlação intraclasse foi de 0,88. A análise fatorial exploratória identificou 13 fatores associados aos componentes do questionário. Também foi elaborada uma versão curta com 29 itens para profissionais. O QSPC-Q profissional (versões curta e estendida) e usuário foram válidos. relevante pensamentos social QSPCQ QSPC Q (QSPC-Q donabedianos QSPCQ. Q. 14 79 saúde testereteste. testereteste reteste. reteste teste-reteste 4 0,921 0921 0 921 3 0,86 086 86 0,86) 088 88 0,88 1 2 versões estendida válidos 7 0,92 092 92 0,8 08 8 0,9 09 9 0,

Abstract The performance evaluation of services through instruments is relevant, as it can support thoughts, actions and political approaches to meet a social need. The objective of the article was to develop and validate the Quality and Strengthening of Primary Care Questionnaire (QSPC-Q) for professionals and users based on Starfield attributes and Donabedian pillars. A mixed sequential study was performed to develop the QSPC-Q. The test was applied to 149 doctors and 795 users of basic health units. Psychometric properties was assessed by testing internal consistency using Cronbach’s alpha and exploratory factor analysis. Reproducibility od scale was assessed using intraclass cognitive and test-retest correlation. The final version of the follow-up consisted of 45 items aimed at physicians (Cronbach’s alpha = 0.921) and 33 at users (Cronbach’s alpha = 0.86); the intraclass respiratory capacity was 0.88. An exploratory factor analysis identified 13 factors associated with the pattern components. A short version with 29 items for professionals was also elaborated. Professional QSPC-Q (short and braided versions) and user QSPC-Q were valid.

Resumo A avaliação do desempenho dos serviços por meio de instrumentos é relevante, pois pode subsidiar pensamentos, ações e abordagens políticas para atender a uma necessidade social. O objetivo do artigo foi desenvolver e validar o Questionário de Qualidade e Fortalecimento da Atenção Primária (QSPC-Q) para profissionais e usuários com base nos atributos Starfield e nos pilares donabedianos. Um estudo sequencial misto foi realizado para desenvolver o QSPC-Q. O teste foi aplicado em 149 médicos e 795 usuários de unidades básicas de saúde. As propriedades psicométricas foram avaliadas testando a consistência interna usando o alfa de Cronbach e a análise fatorial exploratória. A reprodutibilidade da escala foi avaliada por meio da correlação cognitiva intraclasse e teste-reteste. A versão final do questionário foi composta por 45 itens direcionados a médicos (alfa de Cronbach = 0,921) e 33 a usuários (alfa de Cronbach = 0,86); o coeficiente de correlação intraclasse foi de 0,88. A análise fatorial exploratória identificou 13 fatores associados aos componentes do questionário. Também foi elaborada uma versão curta com 29 itens para profissionais. O QSPC-Q profissional (versões curta e estendida) e usuário foram válidos.

The worldwide emergence of viral diseases such as Zika, Dengue, Chikungunya, West Nile and Yellow Fever urge the search for solutions to eliminate their common vector, the Aedes aegypti mosquito. This paper describes the quantitative structure-activity relationship (QSAR) and docking studies of a series of nine 3-(3-aryl-1,2,4-oxadiazol-5-yl)propionic acids (AOPA), 1-9, previously published by our group. Additionally, three new 1,2,4-oxadiazoles, 10-12, have also been synthesized, characterized and studied. The QSAR and docking studies of all compounds, 1-12, clearly indicate that larger hydrophobic substituents such as biphenyl groups attached on position 3 in 1,2,4-oxadiazoles improve the larvicidal activity. It is worthwhile to mention that nanocapsulation of compounds 10-12 were necessary to help their dissolution in water and these three new 1,2,4-oxadiazoles also exhibited approximately equal or higher larvicidal activities compared to the former prototypes at stage L4. Zika Dengue Chikungunya vector mosquito structureactivity structure activity (QSAR 33aryl1,2,4oxadiazol5ylpropionic 33aryl124oxadiazol5ylpropionic aryloxadiazolylpropionic aryl 1,2,4 oxadiazol 5 yl propionic 1 2 4 AOPA, AOPA , (AOPA) 19, 19 9, 9 1-9 group Additionally 1,2,4oxadiazoles, 124oxadiazoles oxadiazoles oxadiazoles, 1012, 1012 10 12, 12 synthesized studied 112, 112 1-12 1,2,4oxadiazoles 10-1 L4 L 33aryl1 4oxadiazol5ylpropionic ylpropionic 124 1,2, (AOPA 1- 4oxadiazoles 101 11 1-1 10- 33aryl oxadiazolylpropionic 1,2 1,

Resumen Este trabajo hace un análisis longitudinal del Índice de Desarrollo de la Educación Básica (Ideb) para los años iniciales de la Enseñanza Básica, en 49 municipios de tamaño medio, en el Estado de São Paulo, entre 2007 y 2019. En el análisis realizado se ha observado el rendimiento medio a lo largo de estos años, la tasa de crecimiento medio de una edición del Ideb a otra y la consecución de objetivos en cada edición. Se utilizó la técnica estadística multivariante de análisis de componentes principales (ACP) para analizar la matriz original de datos de 49 municipios para 7 ediciones del cálculo IDEB. Fue posible establecer los municipios que más se destacaron, según los tres aspectos analizados. Además, llamaron la atención dos resultados: la importancia del año 2013, en relación a los demás, para explicar la varianza de los datos originales y la existencia de una meseta de 2017 a 2019 en el Ideb, verificada para los 49 municipios. (Ideb 4 Paulo 200 ACP (ACP IDEB destacaron analizados Además resultados 2013 demás 201 20 2

Abstract This study makes a longitudinal analysis of the basic education development index (Ideb) for the initial years of the elementary school in 49 medium-sized cities in the State of São Paulo. It takes into account the average performance over the years, the rate of average growth from one Ideb edition to another and the achievement of goals for each edition. The multivariate statistical technique of principal component analysis (PCA) was used to analyze the original data matrix from 49 municipalities for 7 editions of the Ideb calculation. According to the three aspects analyzed, it was possible to establish the cities that stood out the most. In addition, two results caught our attention: the importance of the year 2013, relative to the others, to explain the variance of the original data and the existence of a plateau from 2017 to 2019 in the Ideb of the 49 cities. (Ideb 4 mediumsized medium sized Paulo PCA (PCA calculation analyzed most addition attention 2013 others 201 20 2

Resumo Esse trabalho faz uma análise longitudinal do Índice de Desenvolvimento da Educação Básica (Ideb) para os anos iniciais do Ensino Fundamental, de 49 municípios de médio porte, do Estado de São Paulo, entre os anos de 2007 e 2019. Nessa análise foram levados em conta o desempenho médio ao longo desses anos, a taxa de crescimento médio de uma edição do Ideb para outra e o cumprimento de metas para cada edição. A técnica estatística multivariada de análise de componentes principais (ACP) foi empregada para analisar a matriz original dos dados de 49 municípios por sete edições do cálculo do Ideb. Foi possível estabelecer os municípios que mais se destacaram, de acordo com os três aspectos avaliados. Além disso, dois resultados nos chamaram a atenção: a importância do ano de 2013, em relação aos demais, para explicar a variância dos dados originais e a existência de um platô de 2017 a 2019 no Ideb, verificado para os 49 municípios. (Ideb Fundamental 4 porte Paulo 200 ACP (ACP destacaram avaliados disso atenção 2013 demais 201 20 2

Abstract: Introduction: During the Sars-CoV-2 pandemic, social distancing measures and various other stress factors may have been responsible for impacts on medical students’ mental health. Objective: The purpose of this study is to describe the mental health status of medical students at a college in northeastern Brazil, in the context of the COVID-19 pandemic, investigate symptoms of anxiety and depression, and assess resilience, as well as its possible associated factors. Methodology: A cross-sectional qualitative and quantitative method was used. Data were collected using an online questionnaire among students enrolled in the medical school; data were further processed using quantitative and qualitative statistical analysis separately. The following scales were applied: Generalized Anxiety Disorder Screener (GAD-7), Patient Health Questionnaire-9 (PHQ-9), and Wagnild and Young’s Resilience Scale (RS-25). Results: About one-third of the students lived with moderate or severe anxiety symptoms, almost half had moderate to severe depressive symptoms, and more than half were classified as having low or moderately low resilience. Conclusion: Our findings highlight the difficulty in maintaining high levels of resilience and that the presence of depression or anxiety would be related to lower resilience scores in medical students during remote education. Further studies are needed to establish a causal link with the pandemic. Abstract Introduction SarsCoV2 SarsCoV Sars CoV 2 Sars-CoV- pandemic Objective Brazil COVID19 COVID 19 COVID-1 Methodology crosssectional cross sectional used school separately applied GAD7, GAD7 GAD 7 , (GAD-7) Questionnaire9 Questionnaire 9 Questionnaire- PHQ9, PHQ9 PHQ (PHQ-9) Youngs Young s RS25. RS25 RS 25 . (RS-25) Results onethird one third Conclusion education Sars-CoV COVID1 1 COVID- (GAD-7 (PHQ-9 RS2 (RS-25 (GAD- (PHQ- (RS-2 (GAD (PHQ (RS- (RS

Resumo Introdução: Durante a pandemia de Sars-CoV-2, medidas de distanciamento social e vários outros fatores de estresse foram responsáveis por impactos na saúde mental dos estudantes de Medicina. Objetivo: Este estudo teve como objetivos descrever o estado de saúde mental de estudantes de Medicina de uma faculdade do Nordeste brasileiro, no contexto da pandemia de Covid-19, investigar sintomas de ansiedade e depressão, e avaliar a resiliência e fatores associados. Método: Utilizou-se um método qualitativo e quantitativo transversal. Coletaram-se os dados por meio de questionário on-line aplicado a alunos matriculados na Faculdade de Medicina. Em seguida, os dados foram processados separadamente por meio de análises estatísticas quantitativa e qualitativa. Adotaram-se os seguintes instrumentos: Generalized Anxiety Disorder Screener (GAD-7), Patient Health Questionnaire-9 (PHQ-9) e Wagnild e Young’s Resilience Scale (RS-25). Resultado: Cerca de um terço dos estudantes convivia com sintomas moderados ou graves de ansiedade, quase metade apresentava sintomas depressives de moderados a graves, e mais da metade foi classificada como tendo resiliência baixa ou moderadamente baixa. Conclusão: Nossos achados destacaram que houve dificuldade em manter altos níveis de resiliência e que a presença de depressão ou ansiedade estaria relacionada a menores escores de resiliência em estudantes de Medicina durante o ensino a distância. Mais estudos são necessários para estabelecer um nexo de causalidade com a pandemia. Introdução SarsCoV2, SarsCoV2 SarsCoV Sars CoV 2, 2 Sars-CoV-2 Objetivo brasileiro Covid19, Covid19 Covid 19, 19 Covid-19 associados Método Utilizouse Utilizou se transversal Coletaramse Coletaram online on line seguida qualitativa Adotaramse Adotaram instrumentos GAD7, GAD7 GAD 7 , (GAD-7) Questionnaire9 Questionnaire 9 Questionnaire- PHQ9 PHQ (PHQ-9 Youngs Young s RS25. RS25 RS 25 . (RS-25) Resultado Conclusão distância Sars-CoV- Covid1 1 Covid-1 (GAD-7 (PHQ- RS2 (RS-25 Sars-CoV Covid- (GAD- (PHQ (RS-2 (GAD (RS- (RS

ABSTRACT Objective: To determine the clinical profile of COVID-19 inpatients who were vaccinated prior to hospitalization and to compare the risk factors for death and the 28-day survival rate of between those inpatients vaccinated with one, two, or three doses and unvaccinated COVID-19 inpatients. Methods: This was a retrospective observational cohort study involving COVID-19 patients admitted to a referral hospital in the city of Recife, Brazil, between July of 2020 and June of 2022. Results: The sample comprised 1,921 inpatients, 996 of whom (50.8%) were vaccinated prior to hospitalization. After adjusting the mortality risk for vaccinated patients, those undergoing invasive mechanical ventilation (IMV) had the highest mortality risk (adjusted OR [aOR] = 7.4; 95% CI, 3.8-14.1; p < 0.001), followed by patients > 80 years of age (aOR = 7.3; 95% CI, 3.4-15.4; p < 0.001), and those needing vasopressors (aOR = 5.6; 95% CI, 2.9-10.9; p < 0.001). After adjusting the mortality risk for all patients, having received three vaccine doses (aOR = 0.06; 95% CI, 0.03-0.11; p < 0.001) was the most important protective factor against death. There were progressive benefits of vaccination, reducing the frequency of ICU admissions, use for IMV, and death (respectively, from 44.9%, 39.0% and 39.9% after the first dose to 16.7%, 6.2% and 4.4% after the third dose), as well as significant improvements in survival after each subsequent dose (p < 0.001). Conclusions: Vaccines were effective in reducing illness severity and death in this cohort of COVID-19 inpatients, and the administration of additional doses conferred them with accumulative vaccine protection. Objective COVID19 COVID 19 COVID-1 28day day 28 one two Methods Recife Brazil 202 2022 Results 1921 1 921 1,92 99 50.8% 508 50 8 (50.8% IMV (IMV adjusted aOR [aOR 7.4 74 7 4 95 CI 3.814.1 38141 3.8 14.1 3 14 3.8-14.1 0.001, 0001 0.001 , 0 001 7.3 73 3.415.4 34154 3.4 15.4 15 3.4-15.4 5.6 56 5 6 2.910.9 29109 2.9 10.9 2 9 10 2.9-10.9 0.001. . 0.06 006 06 0.030.11 003011 0.03 0.11 03 11 0.03-0.11 vaccination admissions respectively, respectively (respectively 449 44 44.9% 390 39 39.0 399 39.9 167 16 16.7% 62 6.2 4.4 dose, dose) Conclusions protection COVID1 COVID- 20 192 92 1,9 50.8 (50.8 7. 814 3.814. 3814 38 3. 141 14. 3.8-14. 000 0.00 00 415 3.415. 3415 34 154 15. 3.4-15. 5. 910 2.910. 2910 29 2. 109 10. 2.9-10. 0.0 030 0.030.1 00301 003 011 0.1 0.03-0.1 44.9 39. 16.7 6. 4. 1, 50. (50. 81 3.814 381 3.8-14 41 3.415 341 3.4-15 91 2.910 291 2.9-10 0. 0.030. 0030 01 0.03-0. 44. 16. (50 3.81 3.8-1 3.41 3.4-1 2.91 2.9-1 0.030 0.03-0 (5 3.8- 3.4- 2.9- 0.03- (

RESUMO Objetivo: Traçar o perfil clínico de pacientes internados com COVID-19 que haviam sido vacinados antes da hospitalização e comparar os fatores de risco para óbito e a taxa de sobrevida em 28 dias entre esses internados vacinados com uma, duas ou três doses e pacientes internados com COVID-19 não vacinados. Métodos: Estudo de coorte observacional retrospectivo envolvendo pacientes com COVID-19 internados em um hospital de referência na cidade do Recife (PE) entre julho de 2020 e junho de 2022. Resultados: A amostra foi composta por 1.921 pacientes internados, dos quais 996 (50,8%) haviam sido vacinados antes da hospitalização. Após ajuste do risco de mortalidade para os pacientes vacinados, aqueles submetidos à ventilação mecânica invasiva (VMI) apresentaram o maior risco de mortalidade (OR ajustada [ORa] = 7,4; IC95%: 3,8-14,1; p < 0,001), seguidos pelos pacientes > 80 anos (ORa = 7,3; IC95%: 3,4-15,4; p < 0,001) e aqueles que necessitam de vasopressores (ORa = 5,6; IC95%: 2,9-10,9; p < 0,001). Após ajuste do risco de mortalidade para todos os pacientes, o recebimento de três doses de vacina (ORa = 0,06; IC95%: 0,03-0,11; p < 0,001) foi o fator de proteção mais importante contra o óbito. Houve benefícios progressivos da vacinação, com redução da frequência de internações em UTI, de uso de VMI e de óbitos (de 44,9%, 39,0% e 39,9% após a primeira dose para 16,7%, 6,2% e 4,4% após a terceira dose, respectivamente), bem como melhora significativa na sobrevida após cada dose subsequente (p < 0,001). Conclusões: As vacinas foram efetivas na redução da gravidade da doença e dos óbitos nesta coorte de pacientes internados com COVID-19, e a aplicação de doses adicionais conferiu-lhes proteção vacinal cumulativa. Objetivo COVID19 COVID 19 COVID-1 2 uma Métodos PE (PE 202 2022 Resultados 1921 1 921 1.92 99 50,8% 508 50 8 (50,8% (VMI OR ORa [ORa 7,4 74 7 4 IC95% IC95 IC 3,814,1 38141 3,8 14,1 3 14 3,8-14,1 0,001, 0001 0,001 , 0 001 7,3 73 3,415,4 34154 3,4 15,4 15 3,4-15,4 5,6 56 5 6 2,910,9 29109 2,9 10,9 9 10 2,9-10,9 0,001. . 0,06 006 06 0,030,11 003011 0,03 0,11 03 11 0,03-0,11 vacinação UTI 449 44 44,9% 390 39 39,0 399 39,9 167 16 16,7% 62 6,2 4,4 respectivamente, respectivamente respectivamente) Conclusões COVID19, 19, conferiulhes conferiu lhes cumulativa COVID1 COVID- 20 192 92 1.9 50,8 (50,8 7, IC9 814 3,814, 3814 38 3, 141 14, 3,8-14, 000 0,00 00 415 3,415, 3415 34 154 15, 3,4-15, 5, 910 2,910, 2910 29 2, 109 10, 2,9-10, 0,0 030 0,030,1 00301 003 011 0,1 0,03-0,1 44,9 39, 16,7 6, 4, 1. 50, (50, 81 3,814 381 3,8-14 41 3,415 341 3,4-15 91 2,910 291 2,9-10 0, 0,030, 0030 01 0,03-0, 44, 16, (50 3,81 3,8-1 3,41 3,4-1 2,91 2,9-1 0,030 0,03-0 (5 3,8- 3,4- 2,9- 0,03- (

Biochar from slow pyrolysis under controlled conditions is favorable in the transformation of waste into materials that serve as soil conditioners, and/or environmental remediation. Thus, this work aimed to produce and characterize biochar from cassava waste under different temperature conditions and evaluate interactions with Ca2+ and Pb2+ for agricultural and environmental applications. To investigate the efficiency of the interaction of biochar with nutrients (Ca) and contaminants (Pb), the influence of pH and contact time were evaluated. There was an increase in pH, pHzpc (zero point charge), and condensed aromatic structures in BC, due to the increase in pyrolysis temperature. Also, biochar demonstrated a Pb2+ adsorbed amount of 2.03 to 2.37 mg g-1 and a Ca2+ release capacity of 0.655 to 0.765 mg g-1. In this way, biochar produced from residues of cassava waste can be a viable strategy to enhance agricultural production and reduce environmental contaminants.

Resumo Em 1924, um personagem despontou na imprensa brasileira: o “Professor Mozart”. Seu nome era Mozart Dias Teixeira e, durante as décadas de 1920 e 1930, ele praticou curas em diversas cidades do país, provocando controvérsias entre setores da sociedade. O artigo analisa o caso, dividindo-se em três eixos: introduz o personagem e o debate sobre os seus métodos de cura, mostra como as polêmicas inspiraram produções artísticas que transitaram no seio da população e, por fim, discute a questão do charlatanismo e o problema da liberdade profissional e de culto. O estudo pretende ser uma contribuição à historiografia do espiritismo, do ocultismo e das ciências psíquicas no Brasil.

Abstract In 1924, a new figure appeared on the pages of Brazilian newspapers: “Professor Mozart.” In the 1920s and 1930s, Mozart Dias Teixeira practiced healing in several Brazilian cities, sparking controversy among certain segments of society. A threefold analysis of the case is presented: describing the man himself and the debate surrounding his healing methods; showing how the controversies inspired the production and circulation of art among the population; and discussing the issues of charlatanism and professional and religious freedom. The study intends to contribute to the historiography on spiritism, occultism, and psychic sciences in Brazil.

Abstract The rise of written / printed culture is, without question, one of the most significant events set forth by the beginning of Modernity. Consolidated throughout the 19th century, it brought about a series of new cultural practices that would substantially modify the way we understand the world and communicate with the other, while also providing us with a great diversity of reading practices and materials. During the 19th century, the written word began to address various specific types of population; such is the case of Diario de los Niños (1839-1840) and Los niños pintados por ellos mismos (1843) periodical publications for children which emerged under the initiative of Vicente García Torres, with the objective of contributing to the education of the future citizens required by the new project of society. This text studies these publications through the following axes: a) the first periodical publication aimed at children; b) exemplary models or Mozart for children; c) social representations around childhood.

Resumen Entre los eventos más significativos que la modernidad impulsó está el auge de la cultura escrita/impresa, cuya consolidación en el curso del siglo XIX trajo consigo nuevas prácticas culturales que modificarían sustancialmente la forma de entender el mundo y de comunicarse con el otro, y que revelarían una gran diversidad de prácticas lectoras y de materiales. El siglo XIX comenzó a dirigirse a diversos tipos específicos de población; en este contexto surgieron El Diario de los Niños (1839-1840) y Los niños pintados por ellos mismos (1843), ambas publicaciones debidas a la iniciativa de Vicente García Torres, con el propósito de contribuir a la formación de los futuros ciudadanos que el nuevo proyecto de sociedad requería. Este texto estudia dichas publicaciones a través de los siguientes ejes: a) la primera publicación periódica dirigida a la niñez; b) modelos ejemplares o Mozart para niños; c) representaciones sociales en torno a la niñez.

Considering the bicentenary of Brazil’s Independence in 2022 and that this year was proclaimed by UNESCO as the International Year of Basic Sciences for Sustainable Development, in mid-2021 the Brazilian Chemical Society (SBQ) launched the “Post 2022 Chemistry Movement - Sustainability and Sovereignty”, with the main goal of promoting different activities so that chemistry contributes for the sustainable development and sovereignty of Brazil in the coming years. One of these activities is the proposal of an action plan, with goals to be achieved by 2030 and 2050. This article describes in detail how this action plan was formulated by a working group, with the help of an advisory council and interviews of 18 professionals from universities, the government, industries, the third sector and other organizations. Mimicking the Agenda 2030 SDGs, the resulting action plan is based on two broad Chemistry Sustainable Development Goals: promoting sustainability through chemistry in basic education, and promoting sustainability in the industry and university through science, technology, innovation, and education (STI&E) in chemistry. After the definition of three driving technological challenges in STI&E, they shall be successively implemented through different actions starting in 2023 yet.