Abstract Introduction. Endophytic fungi (EF) in grapevines (Vitis vinifera) have great potential for agricultural applications and may represent possible biological control agents for vineyards. Objective. To isolate and identify endophytic fungi (EF) from grapevine plants with antibiosis capacity against Botrytis cinerea. Materials and methods. Young and mature branches from forty healthy grapevine plants were collected from seven production lots in the Cañete province, Lima, Peru, during March to May 2022. EF isolation was performed on 702 sections of disinfected tissues using potato dextrose agar (PDA) culture medium, and identification was carried out at the genus level. Secondary metabolites were extracted from twenty-eight EF strains to determine the mycelial inhibition of the pathogen. An analysis of variance (ANOVA) was conducted on the evaluated parameters using the Minitab statistical program. Results. A total of 129 EF strains were isolated from leaves and stems of young and mature grapevine branches, encompassing seven genera (Trichoderma, Aspergillus, Alternaria, Cladosporium, Fusarium, Nigrospora, and Stemphylium). The highest frequency was found in leaves and mature branches. Trichoderma and Alternaria were the most frecuent genera in grapevine plants, with 22.48 % and 21.71%, respectively. Metabolites obtained from the EFVH-01 strain of the genus Cladosporium, and EF-99 and EF-70 strains of the genus Alternaria, had the greatest effect on mycelial inhibition of the pathogen. Conclusions. Strains of endophytic fungi from the genera Cladosporium and Alternaria showed antibiosis capacity against Botrytis cinerea at the laboratory scale, which could potential biocontrol agents of pathogens in grapevine cultivation.

Resumen Introducción. Los hongos endófitos (HE) de la vid (Vitis vinifera) tienen un gran potencial de aplicación en la agricultura y pueden representar posibles agentes de control biológico de los viñedos. Objetivo. Aislar e identificar los hongos endófitos (HE) de plantas de vid con capacidad de antibiosis hacia Botrytis cinerea. Materiales y métodos. Se colectaron ramas jóvenes y maduras de cuarenta plantas sanas de vid de siete lotes de producción en la provincia de Cañete, Lima, Perú, durante los meses de marzo a mayo 2022. El aislamiento de HE se realizó de 702 secciones de tejidos desinfectados en medio de cultivo papa dextrosa agar (PDA) y la identificación fue a nivel de género. Se extrajeron metabolitos secundarios de veintiocho cepas de HE para determinar la inhibición micelial del patógeno. Se llevó a cabo un análisis de varianza (ANDEVA) de los parámetros evaluados con el programa estadístico Minitab. Resultados. Se aislaron un total de 129 cepas de HE de hojas y tallos de ramas jóvenes y maduras de vid, que correspondieron a siete géneros (Trichoderma, Aspergillus, Alternaria, Cladosporium, Fusarium, Nigrospora y Stemphylium). La mayor frecuencia se presentó en las hojas y rama madura. Trichoderma y Alternaria fueron los géneros más frecuentes en las plantas de vid con 22,48 % y 21,71 %, respectivamente. Los metabolitos obtenidos de las cepas HEVH-01 del género Cladosporium, HEV-99 y HEV-70 del género Alternaria, tuvieron mayor efecto en la inhibición micelial del patógeno. Conclusiones. Cepas de hongos endofitos del género Cladosporium y Alternaria mostraron capacidad de antibiosis hacia Botrytis cinerea a escala de laboratorio, los cuales podrían ser potenciales biocontroladores de patógenos en el cultivo de vid.

RESUMEN: Dado que los algoritmos de aprendizaje automático dan resultados más fiables, en los últimos años han sido utilizados en el campo de la salud. Las variables orbitales dan resultados muy exitosos a la hora de clasificar correctamente el sexo. Esta investigación se ha centrado en la determinación del sexo utilizando determinadas variables obtenidas a partir de las imágenes orbitales de la tomografía computarizada (TC) mediante el uso de algoritmos de aprendizaje automático (AA). En este estudio se probaron 12 variables determinadas en 600 imágenes orbitales de 300 individuos (150 hombres y 150 mujeres) con diferentes AA. Se utilizaron algoritmos de AA de árbol de decisión (DT), K-Nearest Neighbour, regresión logística (RL), Random Forest (RF), análisis discriminante lineal (ADL) y Naive Bayes (NB) para el aprendizaje no supervisado. Los análisis estadísticos de las variables se realizaron con el programa Minitab® 21.2 (64 bits). La tasa de ACC de los algoritmos NB, DT, KNN y RL se encontró en % 83, mientras que la tasa de ACC de los algoritmos ADL y RFC se determinó en % 85. Según el análisis de Sharp, la variable con el mayor grado de efecto se encontró como BOW. El estudio determinó el sexo con alta precisión en las proporciones de 0,83 y 0,85 mediante el uso de las variables de las imágenes de TC orbitales, y se adquirieron los datos morfométricos relacionados de la población en cuestión, enfatizando la variación racial.

SUMMARY: Since machine learning algorithms give more reliable results, they have been used in the field of health in recent years. The orbital variables give very successful results in classifying sex correctly. This research has focused on sex determination using certain variables obtained from the orbital images of the computerized tomography (CT) by using machine learning algorithms (ML). In this study 12 variables determined on 600 orbital images of 300 individuals (150 men and 150 women) were tested with different ML. Decision tree (DT), K-Nearest Neighbour (KNN), Logistic Regression (LR), Random Forest (RF), Linear Discriminant Analysis (LDA), and Naive Bayes (NB) algorithms of ML were used for unsupervised learning. Statistical analyses of the variables were conducted with Minitab® 21.2 (64-bit) program. ACC rate of NB, DT, KNN, and LR algorithms was found as % 83 while the ACC rate of LDA and RFC algorithms was determined as % 85. According to Shap analysis, the variable with the highest degree of effect was found as BOW. The study has determined the sex with high accuracy at the ratios of 0.83 and 0.85 through using the variables of the orbital CT images, and the related morphometric data of the population under question was acquired, emphasizing the racial variation.

Alzheimer's disease (AD) is the most common cause of dementia worldwide. Fifty million people today are affected by this disease globally. AD has had a tremendous impact on the affected individual, caregiver, and society, in both developed and developing nations. Donepezil—chitosan-gold nanocomposite (Donz-CS-AuNPs) was prepared by co-precipitation technique. Placket-Burman experimental design was used in this work to estimate the effect of the three independent variables (concentration of chitosan, gold, and donepezil) on the dependent variables (loading efficiency, and particle size) by using Minitab 18.1 software. The quantities for the independent variables used were: 10 and 40 mg of donepezil, 24.6 and 73.8 mg of gold, and 500 and 1500 mg of chitosan. The Donz-CS-AuNPs were characterized using energy dispersive X-ray (EDX) analysis, X-ray diffraction (XRD), scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), UV-Vis spectroscopy and release study. The results of EDX showed strong signals of Au (1.5–2, 2–2.5 and 9.5–10 keV), which confirmed the specific gold peaks from the Donz-CS-AuNPs. The XRD pattern of Donz-CS-AuNPs nanocomposites showed the existence of AuNPs peak at 2θ= 38.2°, 43.8° and 64.5°. The SEM images demonstrated spherical shapes of the AuNPs. In the in vitro release study, the release increased steeply and reached 75% after 1440 min. Alzheimers Alzheimer s (AD worldwide globally individual caregiver society nations Donepezilchitosangold Donepezil chitosan DonzCSAuNPs Donz CS (Donz-CS-AuNPs coprecipitation co precipitation technique PlacketBurman Placket Burman concentration donepezil loading efficiency size 181 18 1 18. software 4 246 24 6 24. 738 73 8 73. 50 150 Xray X ray (EDX analysis XRD, , (XRD) SEM, (SEM) FTIR, FTIR (FTIR) UVVis UV Vis study 1.5–2, 152 5 2 (1.5–2 225 2–2. 9510 9 9.5–1 keV, keV keV) DonzCSAuNPs. 2θ θ 382 38 38.2° 438 43 43.8 645 64 64.5° 75 144 min 7 15 (XRD (SEM (FTIR 1.5–2 (1.5– 22 2–2 951 9.5– 3 38.2 43. 64.5 14 1.5– (1.5 2– 95 9.5 38. 64. 1.5 (1. 9. 1. (1 (

ABSTRACT Objective: To determine the perception and concerns physicians and pharmacists have about generic drugs on three annual drug price lists in Trinidad. Method: Windows® Excel 2007 and Minitab® version 17 examined the price lists and a self-administered questionnaire was used to perform a non-randomized, cross-sectional study with a convenient sampling of physicians and pharmacists after obtaining written consent. Results: Physicians (78.6%) and pharmacists (87.1%) agreed and strongly agreed respectively that there are medical conditions for which brand name drugs are preferred including cardiovascular conditions and diabetes; which were comprised in the five major medication categories on the national drug price lists. Overall, physicians and pharmacists showed a ‘Good’ to ‘Excellent’ perception of generic drugs but had some safety and efficacy concerns. Lack of reporting of adverse drug reactions and quality issues by health professionals was also observed. Conclusion: Education and communication among patients, physicians and pharmacists can improve the perception of generic drugs; hence, increase confidence in prescribing, dispensing and patient management.

ABSTRACT Active aging is based on four pillars: health, safety, participation, and lifelong learning. These pillars help individuals improve their quality of life throughout the aging process. Objective: To analyze the effectiveness of the Active Aging Program; identify the sociodemographic profile of the participants; identify prevalent diseases in the initial evaluation; and assess the results of the program after one year of follow-up. Methods: This is a quantitative, cross-sectional, exploratory, desk research, and descriptive study. Data from 545 employees of University of São Paulo participating in the Active Aging Program of the University Teaching Hospital of the University of São Paulo (HU-USP) between 2015 and 2018 were analyzed using the Minitab Program. For data analysis, Pearson's chi-square test was used to determine the association between Groups A and B. For continuous measures, the paired t-test was used to verify differences in means, adopting a 95% confidence interval and significance level of 0.05. Results: Statistically significant correlations were found when crossing sex with smoking; sex with triglycerides; age with risk factors for cardiovascular diseases, being the age group 40–59 statistically more significant; physical activity with risk factors for cardiovascular diseases; and body mass index at program entry with the one-year result. Conclusion: The study expanded knowledge about risk factors for cardiovascular diseases and provided important information for the continuity of the program. health safety participation learning process Objective participants evaluation followup. followup follow up. up follow-up Methods quantitative crosssectional, crosssectional cross sectional, sectional cross-sectional exploratory research 54 HUUSP HU USP (HU-USP 201 analysis Pearsons Pearson s chisquare chi square B measures ttest t means 95 005 0 05 0.05 Results smoking triglycerides 4059 40 59 40–5 oneyear result Conclusion 5 20 9 00 0.0 405 4 40– 2 0.

RESUMO O envelhecimento ativo se apoia em quatro pilares: saúde, segurança, participação e aprendizagem ao longo da vida. Esses pilares auxiliam os indivíduos na qualidade de vida ao longo do processo de envelhecimento. Objetivo: Analisar a efetividade do Programa Envelhecimento Ativo; identificar o perfil sociodemográfico dos participantes; identificar patologias predominantes na avaliação inicial; e verificar os resultados do programa após um ano de acompanhamento. Métodos: Trata-se de pesquisa quantitativa, de caráter transversal, exploratória, documentária e descritiva. Foram analisados os dados de 545 funcionários da Universidade de São Paulo que participaram do Programa do Envelhecimento Ativo do Hospital Universitário da Universidade de São Paulo (HU-USP) no período de 2015 a 2018. Os dados foram analisados pelo Programa Minitab. Na análise de dados, usou-se o Qui-quadrado para testar a associação entre os grupos. Já para medida contínua, utilizou-se o Teste T Pareado, para verificar se as médias eram diferentes. Nas análises, foi usado um período de confiabilidade de 95% e nível de relevância de 0,05. Resultados: Foram encontradas correlações estatisticamente expressivas no cruzamento de sexo com tabagismo; sexo com triglicérides; idade com fatores de risco para doenças cardiovasculares sendo que a faixa etária de 40–59 foi estatisticamente mais significativa; atividade física com prevalência de fatores de riscos para doenças cardiovasculares; e índice de massa corpórea inicial com o resultado após um ano. Conclusão: A pesquisa ampliou o conhecimento a respeito dos fatores de risco para doenças cardiovasculares e forneceu informações importantes para a continuidade do programa. saúde segurança Objetivo participantes acompanhamento Métodos Tratase Trata quantitativa transversal exploratória descritiva 54 HUUSP HU USP (HU-USP 201 2018 Minitab usouse usou Quiquadrado Qui quadrado grupos contínua utilizouse utilizou Pareado diferentes análises 95 005 0 05 0,05 Resultados tabagismo triglicérides 4059 40 59 40–5 significativa Conclusão 5 20 9 00 0,0 405 4 40– 2 0,

Abstract This paper explores the use of novel lightweight concrete as an alternative material, focusing on Cellular Lightweight Foam Concrete (CLFC), renowned for its strength, low weight, thermal insulation, and sustainability. The study encompasses a thorough review of literature focusing on the evolution of lightweight concrete, experimental investigation including mix design variations and mechanical property analysis, statistical analysis using MINITAB software, SEM and EDS interpretation, and construction of model POD. Regression analysis was performed to investigate on the factors influencing compressive strength, revealing significant predictors such as cement, fly ash, water, and density, paving the way for enhanced concrete mixes. Characterization studies such as SEM and EDS were performed to analyse the formation of elements that contribute to the strength parameter. Moreover, the study underscores the potential of utilizing steam curing cycle to achieve early compressive strength in concrete mixes. Ultimately, the research aims to revolutionize construction practices by advocating for the widespread adoption of CLFC and innovative construction techniques to meet the demands of low-cost, eco-friendly housing. material CLFC, , (CLFC) weight insulation sustainability software interpretation POD cement ash water density mixes parameter Moreover Ultimately lowcost, lowcost cost, cost low-cost ecofriendly eco friendly housing (CLFC

Resumo A criação de bezerras é uma das atividades mais importantes na bovinocultura leiteira, visto que estas serão os animais de reposição do rebanho. Objetivou-se avaliar o efeito da estação de nascimento da bezerra no desenvolvimento na fase de cria e desempenho reprodutivo e produtivo. O experimento foi conduzido na Fazenda Experimental Glória, da Universidade Federal de Uberlândia. Foram avaliadas 74 bezerras nascidas de janeiro/2018 a março/2020, desde o primeiro dia de vida ao final da sua primeira lactação. Os animais foram categorizados de acordo com a estação de nascimento: primavera/verão (outubro a março) e outono/inverno (abril a setembro). Durante o aleitamento foi avaliado o peso dos animais nos dias: 0, 30, 60 após o nascimento e no desaleitamento. A temperatura retal, o escore de fezes, a ingestão de alimento e o comportamento animal foram monitorados diariamente. Na vida adulta foram avaliadas data da cobertura fértil, do parto e monitorada a produção de leite durante a primeira lactação. As variáveis analisadas foram: ganho de peso durante o aleitamento, ocorrência de doenças na fase de aleitamento, porcentagem de novilhas que pariram, idade ao primeiro parto e média de produção de leite da primeira lactação de acordo com a estação de nascimento. As variáveis contínuas foram analisadas por análise de variância e as variáveis binomiais por regressão logística no programa MINITAB. As bezerras nascidas na estação outono/inverno apresentam maior peso aos 30 dias, porém esta diferença foi compensada durante o aleitamento, não interferindo no desempenho reprodutivo e produtivo. leiteira rebanho Objetivouse Objetivou se produtivo Glória Uberlândia 7 janeiro2018 janeiro 2018 janeiro/201 março2020 março 2020 março/2020 primaveraverão primavera verão outubro outonoinverno outono inverno abril setembro. setembro . setembro) dias 0 6 desaleitamento retal fezes diariamente fértil pariram MINITAB 3 janeiro201 201 janeiro/20 março202 202 março/202 janeiro20 20 janeiro/2 março20 março/20 janeiro2 2 janeiro/ março2 março/2 março/

Abstract Raising heifers is one of the most important activities in dairy farming because heifers eventually replace the herd. This study was performed to evaluate how the calf’s birth season affects its early development and its reproductive and productive performance. The experiment was conducted at the Glória Experimental Farm of the Federal University of Uberlândia, Minas Gerais, Brazil. In total, 74 female calves born from January 2018 to March 2020 were evaluated from the first day of life to the end of their first lactation. The animals were classified according to their season of birth: spring/summer (October–March) or fall/winter (April–September). During the initial phase of life, the animals’ weights were assessed on days 0, 30, and 60 after birth and at weaning. The rectal temperature, fecal score, feed intake, and animal behavior were recorded daily. In the mature phase of life, the dates of conception and calving were evaluated, and milk production during the first lactation was monitored. The following variables were analyzed according to season of birth: weight gain and occurrence of diseases during the initial phase, percentage of heifers that calved, age at first calving, and average milk production during the first lactation. Continuous variables were analyzed by analysis of variance, and binomial variables were analyzed by logistic regression using the Minitab software program. Calves born in fall/winter had a higher weight at 30 days; however, this difference was compensated for during the initial phase and did not interfere with reproductive and productive performance. herd calfs calf s performance Uberlândia Gerais Brazil total 7 201 202 springsummer spring summer October–March OctoberMarch October (October–March fallwinter fall winter April–September. AprilSeptember April–September . April September (April–September) 0 6 weaning temperature score intake daily monitored calved variance program 3 however 20 (April–September 2

[Objective] The objective of this study was to evaluate the short-term response of four different odor mitigation measures in a homogenization tank of a university WWTP. [Methodology] Aeration, addition of lime, addition of iron sulfate, and addition of the commercial product BiOWiSH® Odor were implemented over a study period equal to four hydraulic retention times. Monitoring was conducted for the influent water and within the tank for each period, including a baseline measurement for comparison. pH, oxidation-reduction potential, and dissolved oxygen were measured in triplicates every 30 minutes, along with the concentration of dissolved sulfide. An odor perception survey was administered to WWTP visitors, evaluating intensity, offensiveness, and character with a total of 15 surveys per period. Differences between the mitigation measures and baseline were determined using t-student tests for quantitative data and Mood's medians for qualitative data. Minitab 2019 was used with a confidence level of 95%. [Results] All the mitigation measures significantly decreased the concentration of dissolved sulfide in the tank. Aeration prevented oxygen depletion, reducing conditions, and acid fermentation, favoring the oxidation of odorous compounds. It was the only studied mitigation measure that led to a reduction in intensity and offensiveness of the odor. [Conclusions] The application of aeration induced changes in the tank's behavior and odor perception, confirming its effectiveness. The addition of iron sulfate, lime, and BiOWiSH® did not generate significant changes in odor perception.

[Objetivo] El objetivo de este estudio fue evaluar la respuesta a corto plazo de cuatro diferentes medidas de mitigación de olores en un tanque de homogeneización de una PTAR universitaria. [Metodología] Se aplicaron las medidas de aireación, adición de cal, adición de sulfato de hierro y adición del producto comercial BiOWiSH® odor; durante cuatro tiempos de retención hidráulico. Se monitoreó el afluente y la unidad en cada periodo, utilizando una línea base como comparación de las medidas. Se midió por triplicado cada 30 min el potencial de Hidrógeno, potencial de oxidación reducción, oxígeno disuelto y la concentración de sulfuro disuelto. Se aplicó una encuesta de percepción de olores a visitantes de la PTAR evaluando intensidad, ofensividad y carácter con un total de 15 encuestas por periodo de monitoreo. Se determinaron diferencias entre medidas de mitigación y línea base con pruebas t-student (datos cuantitativos) y medianas de Mood (datos cualitativos). Se utilizó Minitab2019 y un límite de confianza de 95%. [Resultados] Todas las medidas de mitigación disminuyeron significativamente la concentración de sulfuro disuelto en la unidad. La medida aireación evitó el agotamiento de oxígeno, régimen reductivo y fermentación ácida, favoreciendo la oxidación de odorantes, además fue la única medida de mitigación estudiada que generó una reducción en la intensidad y ofensividad del olor. [Conclusiones] La aplicación de aireación generó un cambio en el comportamiento de la unidad y la percepción de olor, confirmando su efectividad. La adición de sulfato de hierro, cal y BiOWiSH® no generaron cambios significativos en la percepción de olor.

Resistant infectious microorganisms are causing a worldwide emerging problem, called antimicrobial resistance. To avoid this outbreak, new antimicrobial technologies are necessary. Silver nanoparticles (AgNPs) are known for their antibacterial properties and several studies have focused on their synthesis, characterization, and biological assays. One possibility to synthesize AgNPs is through gamma radiation, known as radiolytic synthesis. This work focuses on the radiolytic synthesis of AgNPs capped into a mesoporous silica nanoparticle aiming at an antimicrobial application. The variants of the radiolytic synthesis, which may influence the AgNPs formation, were studied and statistically compared by Design of Experiments Factorial Design in Minitab Software. The Ag content is statically dependent on dose, volume, and pH, as well as on two parameters interaction: [Ag+]-pH and [Ag+]-volume pH interaction. Transmission electron microscopy and nitrogen adsorption analyses indicated the presence of subnanometric AgNPS located inside the mesopores. Silver nanoagglomerates were also found by transmission electron microscopy, which could be formed by silver oxides, as shown in X-ray photoelectron spectroscopy. AgNPs reduce the specific surface area of the silica nanoparticle, while the matrix morphology remains. The nanocomposites presented preliminary biocompatibility observed in in vitro biological assay using fibroblasts, which support their application in biological systems as antimicrobial substitutes. problem resistance outbreak necessary (AgNPs characterization assays radiation formation Software dose volume interaction Ag+pH AgpH Ag+ Ag+volume Agvolume mesopores oxides Xray X ray spectroscopy remains fibroblasts substitutes

RESUMEN Objetivo: Investigar el impacto de la pandemia de la COVID-19 en las dimensiones personales y su relación con el contexto de trabajo de los técnicos de enfermería que actuaban en las UTI. Método: Estudio transversal de carácter mixto (paralelo convergente). Participaron 229 técnicos de enfermería de unidades de cuidados intensivos que respondieron un cuestionario. El estudio mixto se realizó con la ayuda del software IRaMuTeQ para verificación lexicográfica y análisis de similitud del corpus y el software Minitab 19 para comparación entre medias y regresión logística. Resultados: Se constató que la mayor repercusión en la vida de los técnicos de enfermería fue el miedo. Los profesionales tenían estrés y ansiedad como consecuencia del miedo a la contaminación por el Coronavirus y la diseminación a los familiares. Conclusión: La pandemia afectó el cotidiano personal de los técnicos de enfermería, en el mismo contexto de trabajo, de formas diversas. Objetivo COVID19 COVID COVID-1 UTI Método paralelo convergente. convergente . convergente) 22 cuestionario 1 logística Resultados familiares Conclusión diversas COVID1 COVID- 2

ABSTRACT Objective: To investigate the impact of the COVID-19 pandemic on personal dimensions and its relationship with the work context of nursing technicians who worked in ICUs. Method: A cross-sectional mixed-method study (convergent parallel). A total of 229 nursing technicians from intensive care units participated and responded a questionnaire. The study was conducted using the IRaMuTeQ software for lexicographic verification and similarity analysis of the corpus and the Minitab 19 software for comparison between means and logistic regression. Results: Fear was found that the biggest impact on the lives of nursing technicians. The professionals experienced stress and anxiety as a consequence of the fear of Coronavirus infection and its transmission to their families. Conclusion: The pandemic affected the daily personal lives of nursing technicians, in the same work context, in different ways. Objective COVID19 COVID COVID-1 ICUs Method crosssectional cross sectional mixedmethod mixed method convergent parallel. parallel . parallel) 22 questionnaire 1 regression Results families Conclusion ways COVID1 COVID- 2

RESUMO Objetivo: Investigar a repercussão da pandemia da COVID-19 nas dimensões pessoais e sua relação com o contexto laboral dos técnicos de enfermagem que atuaram em unidades de terapia intensiva. Método: Pesquisa transversal de natureza mista (paralelo convergente). Participaram 229 técnicos de enfermagem de unidades de terapia intensiva que responderam um questionário. O estudo foi realizado com auxílio do software IRaMuTeQ para verificação lexicográfica e análise de similitude do corpus e o software Minitab 19 para comparação entre médias e regressão logística. Resultados: Verificou-se que a maior repercussão na vida dos técnicos de enfermagem foi o medo. Os profissionais apresentaram estresse e ansiedade que se configuraram como desdobramento do medo de contaminação pelo Coronavírus e disseminação para familiares. Conclusão: A pandemia afetou de formas distintas o cotidiano de vida pessoal dos técnicos de enfermagem, inseridos no mesmo contexto laboral. Objetivo COVID19 COVID COVID-1 Método paralelo convergente. convergente . convergente) 22 questionário 1 logística Resultados Verificouse Verificou familiares Conclusão COVID1 COVID- 2

ABSTRACT Objectives: The objective was to evaluate the longevity of ceramic restorative materials in the manufacture of endocrown restorations, through an in vitro study on surface roughness and mechanical strength. Methods: Three restorative materials were evaluated and assigned to experimental groups (n=10 disc specimens): Leucite Reinforced Ceramic, Lithium Disilicate and Nanoceramic Resin. These restorative materials were evaluated for surface before and after aging (n=02 specimens) under a stereomicroscope. The specimens were submitted to the average surface roughness test (Ra) (n=10) in a contact roughness meter before and after aging. As well as the biaxial flexural strength test (n=10), after aging, up to a test speed of 0.5 mm/min. Aging was carried out in a thermocycler, with 5,000 cycles with baths of 5 °C ± 1 ° and 55 °C ± 1 °. Fragments after fracture were observed under a stereomicroscope. The data obtained were tabulated and analyzed using the Minitab statistical program. Results: The surfaces of the specimens do not show changes between the restorative materials and also in relation to aging. For the roughness data, the restorative material factors (p=0.867) and aging (p=0.321) were not statistically significant. The DIS group presented the highest values of fracture resistance (p=0.000), in relation to the LEU and REN groups, which were statistically similar. The same statistical pattern was identified for post-fracture fragment data (p=0.030). Conclusions: The aging factors and restorative material do not interfere with the surface roughness performance. However, the mechanical performance and number of fragments after fracture is affected by the restorative material. Objectives restorations Methods n=10 n10 n 10 (n=1 Ceramic Resin n=02 n02 02 (n=0 stereomicroscope Ra (Ra n=10, , 05 0 0. mmmin mm min mm/min thermocycler 5000 000 5,00 C program Results p=0.867 p0867 p 867 (p=0.867 p=0.321 p0321 321 (p=0.321 significant p=0.000, p0000 p=0.000 (p=0.000) similar postfracture post p=0.030. p0030 p=0.030 . 030 (p=0.030) Conclusions However n=1 n1 (n= n=0 n0 500 00 5,0 p=0.86 p086 86 (p=0.86 p=0.32 p032 32 (p=0.32 p000 p=0.00 (p=0.000 p003 p=0.03 03 (p=0.030 n= (n 50 5, p=0.8 p08 8 (p=0.8 p=0.3 p03 3 (p=0.3 p00 p=0.0 (p=0.00 (p=0.03 p=0. p0 (p=0. (p=0.0 p=0 (p=0 p= (p= (p

RESUMO Objetivos: Objetivou-se avaliar a longevidade de materiais restauradores cerâmicos na confecção de restaurações endocrowns, através de um estudo in vitro sobre rugosidade superficial e resistência mecânica. Métodos: Três materiais restauradores foram avaliados e distribuídos em grupos experimentais (n=10 espécimes em disco): Cerâmica Reforçada por Leucita, Dissilicato de Lítio e Resina Nanocerâmica. Estes materiais restauradores foram avaliados quanto a superfície antes e após ao envelhecimento (N=2 espécimes) em estereomicroscópio. Os espécimes foram submetidos ao ensaio de rugosidade superficial média (Ra) (N=10) em rugosímetro de contato antes e após o envelhecimento. Como também, ao teste de resistência à flexão biaxial (N=10), após envelhecimento, em uma velocidade de ensaio de 0,5 mm/min. O envelhecimento foi realizado uma termocicladora, sendo 5.000 ciclos com banhos de 5 °C ± 1° e 55 °C ± 1°. Os fragmentos após fratura foram observados em estereomicroscópio. Os dados obtidos foram tabulados e analisados no programa estatístico Minitab. Resultados: As superfícies dos espécimes não mostram alterações entre os materiais restauradores e também em relação ao envelhecimento. Para os dados de rugosidade, os fatores materiais restauradores (p=0,867) e envelhecimento (p=0,321) não foram estatisticamente significativos. O grupo DIS apresentou os maiores valores de resistência à fratura (p=0,000), em relação aos grupos LEU e REN que foram estatisticamente semelhantes. O mesmo padrão estatístico foi identificado para os dados de fragmentos após a fratura (p=0,030). Conclusão: Os fatores envelhecimento e material restaurador não interferem quanto a performance da rugosidade superficial. No entanto, o desempenho mecânico e número de fragmentos após a fratura é afetado pelo material restaurador. Objetivos Objetivouse Objetivou se endocrowns mecânica Métodos n=10 n10 n 10 (n=1 disco disco) Leucita Nanocerâmica N=2 N2 N 2 (N= estereomicroscópio Ra (Ra N=10 N10 (N=10 N=10, , 05 0 0, mmmin mm min mm/min termocicladora 5000 000 5.00 C 1 Minitab Resultados p=0,867 p0867 p 867 (p=0,867 p=0,321 p0321 321 (p=0,321 significativos p=0,000, p0000 p=0,000 (p=0,000) semelhantes p=0,030. p0030 p=0,030 . 030 (p=0,030) Conclusão entanto n=1 n1 (n= N= (N N=1 N1 (N=1 500 00 5.0 p=0,86 p086 86 (p=0,86 p=0,32 p032 32 (p=0,32 p000 p=0,00 (p=0,000 p003 p=0,03 03 (p=0,030 n= (n 50 5. p=0,8 p08 8 (p=0,8 p=0,3 p03 3 (p=0,3 p00 p=0,0 (p=0,00 (p=0,03 p=0, p0 (p=0, (p=0,0 p=0 (p=0 p= (p= (p

RESUMO Objetivo Elaborar um indicador composto denominado Índice Videoquimográfico da Função Glótica – IVFG, a partir de parâmetros da videoquimografia digital, captados pelo exame de videolaringoscopia de alta velocidade de mulheres sem e com alterações laríngeas de etiologia comportamental. Método A amostra foi composta por 92 mulheres, destas 55 apresentaram disfonia comportamental, com presença de alterações laríngeas e vocais, e 37 mulheres sem alterações laríngeas e vocais, entre 18 a 45 anos. A avaliação vocal foi realizada por consenso pela análise perceptivo-auditiva da vogal /a/ em frequência e intensidade habituais, e classificação através do grau geral da disfonia, onde G0 indicou qualidade vocal neutra e G1 a 3 qualidade vocal alterada. As imagens laríngeas foram obtidas pela gravação da emissão da vogal /i/, em frequência e intensidade habituais para análise da videoquimografia digital. A construção do IVFG se deu pela escolha do ponto médio da glote para análise e, elaboração foi realizada regressão logística pelo programa MINITAB 19. Resultados A regressão logística contou com duas etapas, sendo que a etapa 1 constou da análise de todas as variáveis, onde as variáveis abertura máxima e fechamento glótico apresentaram significância estatística (p-valor <0.05) e o modelo se encontrou bem ajustado de acordo com o teste de Hosmer-Lemeshow (p-valor=0,794); na etapa 2, as variáveis selecionadas foram novamente analisadas e o modelo também se mostrou bem ajustado (p-valor=0,198). O IVFG foi definido por IVFG=e^(8,1318-0,2941AbMax-0,0703FechGlo)/1+e^(8,1318-0,2941AbMax-0,0703FechGlo). Conclusão O IVFG apresenta valor de corte igual a 0,71. A probabilidade de acerto é de 81,5%, sensibilidade 76,4%, especificidade de 89,2%.

ABSTRACT Purpose To develop the Videokymographic Index of Glottic Function (VIGF), a composite indicator from digital videokymography parameters, captured by high-speed videolaryngoscopy exams of women with and without laryngeal alterations of behavioral etiology. Methods The sample consisted of 92 women aged between 18 and 45 years. Fifty-five (55) women with behavioral dysphonia, presenting with laryngeal and voice alterations, and thirty-seven (37) women without any laryngeal and voice alterations. Voice evaluation was performed by consensus via an auditory-perceptual analysis of the sustained vowel /a/ at a habitual pitch and loudness. Voice classification was obtained by means of a general degree of dysphonia, where G0 indicated neutral voice quality and G1 to G3 indicated altered voice quality. Laryngeal images were captured via digital videokymography analysis of a sustained vowel /i/ at a habitual pitch and loudness. The VIGF was based on the midpoint of the glottal region for analysis. Logistic regression was performed using the MINITAB 19 program. Results Logistic regression was composed of two stages: Stage 1 consisted of the analysis of all variables, where the maximum opening and closed quotient variables showed statistical significance (p-value <0.05) and the model was well adjusted according to the Hosmer-Lemeshow test (p-value=0.794). Stage 2 consisted of the re-analysis of the selected variables, also showing a well-adjusted model (p-value=0.198). The VIGF was defined as follows: VIGF=e^(8.1318-0.2941AbMax-0.0703FechGlo)/1+e^(8.1318-0.2941AbMax-0.0703FechGlo). Conclusion The VIGF demonstrated a cut-off value equal to 0.71. The probability of success was 81.5%, sensitivity 76.4%, and specificity 89.2%.

Resumen Este trabajo de investigación cualitativa muestra los resultados del seguimiento realizado a los profesores de la carrera de ingeniería Industrial de la Facultad de Ciencias de la Ingeniería y Tecnología de la Universidad Autónoma de Baja California durante los semestres 2020-1, 2020-2 y 2021-1. Dicho seguimiento se dio con apoyo de un tablero de control de indicadores de desempeño académico que mide el grado de cumplimiento de las actividades académicas y culturales que contribuyen a la formación de estudiantes. Entre los resultados procesados con Minitab 17 destaca que los profesores obtuvieron una calificación de 90 en su desempeño como docentes según la opinión de los estudiantes. Las conclusiones confirman que la implementación de un tablero de indicadores de desempeño académico permite mantener y garantizar la calidad educativa.

Abstract This qualitative research work shows the results of the monitoring carried out on the professors of the Industrial Engineering career of the Faculty of Engineering Sciences and Technology of the Universidad Autónoma de Baja California during the semesters 2020-1, 2020-2 and 2021- 1. Said follow-up was given with the support of a control panel of academic performance indicators that measures the degree of compliance with the academic and cultural activities that contribute to the formation of students. Among the results processed with Minitab 17, it stands out that the teachers obtained a grade of 90 in their performance as teachers according to the opinion of the students. The conclusions confirm that the implementation of a dashboard of academic performance indicators allows to maintain and guarantee educational quality.

Resumo Este trabalho de pesquisa qualitativa mostra os resultados do monitoramento realizado nos professores da carreira de Engenharia Industrial da Faculdade de Ciências da Engenharia e Tecnologia da Universidade Autônoma da Baixa Califórnia durante os semestres 2020-1, 2020-2 e 2021-1. Esse acompanhamento se deu com o apoio de um painel de controle de indicadores de desempenho acadêmico que mede o grau de cumprimento das atividades acadêmicas e culturais que contribuem para a formação dos alunos. Dentre os resultados processados com o Minitab 17, destaca-se que os professores obtiveram nota 90 em seu desempenho como professores segundo a opinião dos alunos. As conclusões confirmam que a implementação de um dashboard de indicadores de desempenho académico permite manter e garantir a qualidade educativa.

ABSTRACT Introduction: Cardiovascular risk is currently considered one of the most dangerous triggers of chronic diseases, as it is the cause of thousands of deaths worldwide. Objective: To create a logistic regression model for a desktop application that estimates cardiovascular risk using anthropometric measures and different formulas, and thus identify the prevalence of cardiovascular risk in the study population. Methods: A descriptive, observational and cross-sectional study was carried out with 169 workers from a university in southwestern Colombia, to whom anthropometric measurements such as weight, height and waist circumference were taken, applying the protocol of the International Society for the Advancement of Kinanthropometry. In addition, a structured survey was applied to collect sociodemographic data. The data were analyzed with a Minitab statistical package, using univariate description for qualitative variables as absolute and relative frequencies, as well as mean and standard deviation for quantitative variables. The resulting desktop application was made with the JAVA platform. Results: In a population of 93 women and 76 men, a logistic regression model was found, using the quantitative predictor variables of weight and waist circumference, significantly related to the cardiovascular risk response variable, as well as the qualitative variable of gender. Applying the model, prevalence of cardiovascular risk was found to be 53.85 % in the working population of the university institution. Conclusions: Cardiovascular risk is a phenomenon that is gaining more and more strength, while measuring weight and waist circumference is a way for determining such risk, a fact that will facilitate the prevention and control of cardiovascular diseases in the primary care level.

RESUMEN Introducción: El riesgo cardiovascular es considerado actualmente como uno de los más peligrosos desencadenantes de enfermedades crónicas, ya que es el causante de miles de muertes a nivel mundial. Objetivo: Generar un modelo de regresión logística para una aplicación de escritorio que estime el riesgo cardiovascular por medidas antropométricas y diferentes fórmulas, y así identificar la prevalencia del riesgo cardiovascular en la población objeto de estudio. Métodos: Estudio observacional descriptivo de corte transversal realizado en 169 trabajadores de una institución universitaria del suroccidente colombiano, a los cuales se les tomaron medidas antropométricas de peso, talla y circunferencia de cintura aplicando el protocolo de la Sociedad Internacional de Avances para la Cineantropometría. Además, se aplicó una encuesta estructurada para recolectar datos sociodemográficos. Los datos se analizaron con un paquete estadístico minitab con una descripción univariada para variables cualitativas como frecuencias absolutas y relativas; media y desviación estándar para las cuantitativas. La aplicación de escritorio resultado se realizó con la plataforma JAVA. Resultados: En una población de 93 mujeres y 76 hombres se halló un modelo de regresión logística con las variables cuantitativas predictoras peso y circunferencia de cintura con relación significativa a la variable respuesta riesgo cardiovascular, al igual que la variable cualitativa género. Aplicando el modelo se halló prevalencia de riesgo cardiovascular de 53,85 % en la población laboralmente activa de la institución universitaria. Conclusiones: El riesgo cardiovascular es un fenómeno que cada vez gana más fuerza, y la toma de peso y circunferencia de cintura generan una determinación de este riesgo, hecho que facilitará la prevención y el control de enfermedades cardiovasculares en la atención primaria.

Resumo O modelo linear de produção e consumo prejudica o meio ambiente e acelera a escassez de recursos naturais. Em contrapartida, a Economia Circular (EC) surge como modelo que visa manter produtos, componentes e materiais em seu mais alto nível de utilidade e valor o tempo todo. Esta pesquisa busca responder à seguinte questão-problema: como a literatura internacional aborda a relação entre Energias Renováveis e Economia Circular em um contexto industrial? Como objetivo geral, tem-se: identificar, na literatura internacional, como os termos Energias Renováveis e Economia Circular se relacionam no contexto industrial. A metodologia aplicada consistiu em uma revisão sistemática da literatura associada à bibliometria nas bases de dados da Scopus e Web of Science, aplicando os termos: “renewabl* energ*” AND “circular economy” AND “industr*”. Os indicadores bibliométricos foram analisados com o auxílio dos softwares MINITAB e VOSviewer. A partir da amostra final, de 88 artigos, os países que mais se destacaram em número de publicações foram a Itália, seguida pela China, Alemanha e Reino Unido. Notou-se que os anos com maior quantidade de publicações foram 2018, 2019 e 2020, sendo que a primeira publicação surgiu em 2012. Dentre os principais resultados, verificou-se que as pesquisas, em sua maioria, são estudos de casos que diagnosticam uma realidade e propõem soluções eficientes junto aos processos produtivos e a redução de impactos ambientais. Por fim, concluiu-se que a Economia Circular é um modelo progressista de produção e consumo, que respeita a limitação dos recursos naturais, ao passo que atende às necessidades humanas.

Abstract The linear model of production and consumption harms the environment and accelerates the scarcity of natural resources. In contrast, the Circular Economy (EC) emerges as a model that aims to keep products, components, and materials at their highest level of usefulness and value at all times. This research seeks to answer the following problem question: how does international literature approach the relationship between Renewable Energies and Circular Economy in an industrial context? The general objective is: to identify, in the international literature, how the terms Renewable Energy and Circular Economy are related in the industrial context. The applied methodology consisted of a systematic review of the literature associated with bibliometrics in the Scopus and Web of Science databases, applying the terms: “renewabl * energ *” AND “circular economy” AND “industr *”. Bibliometric indicators were analyzed with the aid of the MINITAB and VOSviewer softwares. From the final sample of 88 articles, the countries that stood out the most in the number of publications were Italy, followed by China, Germany, and the United Kingdom. It was noted that the years with the largest number of publications were 2018, 2019, and 2020, with the first publication appearing in 2012. Among the main results, it was found that the researches, in its majority, are case studies that diagnose a reality and propose efficient solutions with the production processes and the reduction of environmental impacts. Finally, it was concluded that the Circular Economy is a progressive model of production and consumption, which respects the limitation of natural resources while meeting human needs.

Resumen El modelo lineal de producción y consumo daña el medio ambiente y acelera la escasez de recursos naturales. Por el contrario, la Economía Circular (CE) surge como un modelo que tiene como objetivo mantener los productos, componentes y materiales en su máximo nivel de utilidad y valor en todo momento. Esta investigación busca dar respuesta a la siguiente pregunta problemática: ¿Cómo aborda la literatura internacional la relación entre Energías Renovables y Economía Circular en un contexto industrial? El objetivo general es: identificar, en la literatura internacional, cómo se relacionan los términos Energía Renovable y Economía Circular en el contexto industrial. La metodología aplicada consistió en una revisión sistemática de la literatura asociada a bibliometría en las bases de datos Scopus y Web of Science, aplicando los términos: “renewabl * energ *” AND “economía circular” AND “industr *”. Los indicadores bibliométricos se analizaron con la ayuda de los softwares MINITAB y VOSviewer. De la muestra final, de 88 artículos, los países que más se destacaron en número de publicaciones fueron Italia, seguido de China, Alemania y Reino Unido. Se observó que los años con mayor número de publicaciones fueron 2018, 2019 y 2020, apareciendo la primera publicación en 2012. Entre los principals resultados, se encontró que las investigaciones, en su mayoría, son estudios de caso que diagnostican una realidad y proponen soluciones eficientes con los procesos productivos y la reducción de impactos ambientales. Finalmente, se concluyó que la Economía Circular es un modelo progresivo de producción y consumo, que respeta la limitación de los recursos naturales, al tiempo que satisface las necesidades humanas.