Resumen (Objetivo) El objetivo de este estudio fue evaluar la respuesta, a corto plazo, de cuatro diferentes medidas de control de olores en un tanque de homogeneización de una PTAR universitaria. (Metodología) Se aplicaron la aireación, adición de cal, adición de sulfato de hierro y adición del producto comercial BiOWiSH® Odor, durante cuatro tiempos de retención hidráulica. Se monitoreó el afluente y la unidad en cada periodo, utilizando una línea base como comparación de las medidas. Se midió por triplicado, cada 30 min, el potencial de hidrógeno, potencial de oxidación-reducción, oxígeno disuelto y la concentración de sulfuro disuelto. Se pasó una encuesta de percepción de olores a visitantes de la PTAR, con el propósito de evaluar intensidad, ofensividad y carácter (en total, 15 encuestas por periodo de monitoreo). Se determinaron diferencias entre las medidas de control y la línea base, con pruebas t-student (datos cuantitativos) y medianas de Mood (datos cualitativos). Se usó Minitab2019 y un límite de confianza de 95 %. (Resultados) Todas las medidas de control disminuyeron significativamente la concentración de sulfuro disuelto en la unidad. La aireación evitó el agotamiento de oxígeno, el régimen reductivo y la fermentación ácida, favoreciendo la oxidación de odorantes; además, fue la única medida de control estudiada que generó una reducción en la intensidad y ofensividad del olor. (Conclusiones) La aplicación de aireación generó un cambio en el comportamiento de la unidad y la percepción de olor, hecho que confirma su efectividad. La adición de sulfato de hierro, cal y BiOWiSH® no produjeron modificaciones significativas en la percepción de olor.

Resumo (Objetivo) O objetivo deste estudo foi avaliar a res em curto prazo de quatro diferentes medidas de controle de odores em um tanque de homogeneização de uma ETE universitária. (Metodologia) Foram aplicadas aeração, adição de cal, adição de sulfato de ferro e adição do produto comercial BiOWiSH® Odor durante quatro tempos de detenção hidráulica. O afluente e a unidade foram monitorados em cada período, utilizando uma linha de base como comparação das medições. Foram medidos em triplicata a cada 30 minutos o potencial de hidrogênio, o potencial de oxidação-redução, o oxigênio dissolvido e a concentração de sulfeto dissolvido. Foi aplicado um questionário de percepção de odores aos visitantes da ETE, com o objetivo de avaliar a intensidade, a ofensividade eo carácter (no total, 15 questionários por período de monitorização). Foram determinadas diferenças entre as medidas de controle e a linha de base, com testes t-Student (dados quantitativos) e da mediana de Mood (dados qualitativos). Foram utilizados Minitab2019 e limite de confiança de 95%. (Resultados) Todas as medidas de controle diminuíram significativamente a concentração de sulfeto dissolvido na unidade. A aeração evitou o esgotamento do oxigênio, o regime redutor e a fermentação ácida, favorecendo a oxidação dos odorantes; além disso, foi a única medida de controle estudada que gerou redução na intensidade em a ofensividade do odor. (Conclusões) A aplicação da aeração gerou uma mudança no comportamento da unidade e na percepção do odor, fato que confirma sua eficácia. A adição de sulfato de ferro, cal e BiOWiSH® não produziu modificações significativas na percepção do odor.

Abstract (Objective) This study aimed to evaluate the short-term response of four different odor control measures in a homogenization tank of a university Wastewater Treatment Plant (WWTP). (Methodology) The following were implemented: aeration, adding lime, adding iron sulfate, and adding the commercial product BiOWiSH® Odor over four hydraulic retention times. The effluent and the unit were monitored during each period, using a baseline to compare the measures. Hydrogen potential, oxidation-reduction potential, dissolved oxygen, and dissolved sulfide concentration were measured in triplicate every 30 minutes. An odor perception survey was administered to WWTP visitors to evaluate intensity, offensiveness, and character (15 surveys per monitoring period). Differences were determined between control measures and the baseline using Student’s t-tests (quantitative data) and Mood’s median tests (qualitative data). Minitab 2019 was used with a 95% confidence level. (Results) All control measures significantly reduced the dissolved sulfide concentration in the unit. Aeration prevented oxygen depletion, reductive regime, and acid fermentation, which favored the oxidation of odorants. Aeration was also the only studied control measure that reduced odor intensity and offensiveness. (Conclusions) Applying aeration changed unit behavior and odor perception, which confirms its effectiveness, while adding iron sulfate, lime, and BiOWiSH® did not significantly change odor perception.

Resumen Introducción. Los hongos endófitos (HE) de la vid (Vitis vinifera) tienen un gran potencial de aplicación en la agricultura y pueden representar posibles agentes de control biológico de los viñedos. Objetivo. Aislar e identificar los hongos endófitos (HE) de plantas de vid con capacidad de antibiosis hacia Botrytis cinerea. Materiales y métodos. Se colectaron ramas jóvenes y maduras de cuarenta plantas sanas de vid de siete lotes de producción en la provincia de Cañete, Lima, Perú, durante los meses de marzo a mayo 2022. El aislamiento de HE se realizó de 702 secciones de tejidos desinfectados en medio de cultivo papa dextrosa agar (PDA) y la identificación fue a nivel de género. Se extrajeron metabolitos secundarios de veintiocho cepas de HE para determinar la inhibición micelial del patógeno. Se llevó a cabo un análisis de varianza (ANDEVA) de los parámetros evaluados con el programa estadístico Minitab. Resultados. Se aislaron un total de 129 cepas de HE de hojas y tallos de ramas jóvenes y maduras de vid, que correspondieron a siete géneros (Trichoderma, Aspergillus, Alternaria, Cladosporium, Fusarium, Nigrospora y Stemphylium). La mayor frecuencia se presentó en las hojas y rama madura. Trichoderma y Alternaria fueron los géneros más frecuentes en las plantas de vid con 22,48 % y 21,71 %, respectivamente. Los metabolitos obtenidos de las cepas HEVH-01 del género Cladosporium, HEV-99 y HEV-70 del género Alternaria, tuvieron mayor efecto en la inhibición micelial del patógeno. Conclusiones. Cepas de hongos endofitos del género Cladosporium y Alternaria mostraron capacidad de antibiosis hacia Botrytis cinerea a escala de laboratorio, los cuales podrían ser potenciales biocontroladores de patógenos en el cultivo de vid.

Abstract Introduction. Endophytic fungi (EF) in grapevines (Vitis vinifera) have great potential for agricultural applications and may represent possible biological control agents for vineyards. Objective. To isolate and identify endophytic fungi (EF) from grapevine plants with antibiosis capacity against Botrytis cinerea. Materials and methods. Young and mature branches from forty healthy grapevine plants were collected from seven production lots in the Cañete province, Lima, Peru, during March to May 2022. EF isolation was performed on 702 sections of disinfected tissues using potato dextrose agar (PDA) culture medium, and identification was carried out at the genus level. Secondary metabolites were extracted from twenty-eight EF strains to determine the mycelial inhibition of the pathogen. An analysis of variance (ANOVA) was conducted on the evaluated parameters using the Minitab statistical program. Results. A total of 129 EF strains were isolated from leaves and stems of young and mature grapevine branches, encompassing seven genera (Trichoderma, Aspergillus, Alternaria, Cladosporium, Fusarium, Nigrospora, and Stemphylium). The highest frequency was found in leaves and mature branches. Trichoderma and Alternaria were the most frecuent genera in grapevine plants, with 22.48 % and 21.71%, respectively. Metabolites obtained from the EFVH-01 strain of the genus Cladosporium, and EF-99 and EF-70 strains of the genus Alternaria, had the greatest effect on mycelial inhibition of the pathogen. Conclusions. Strains of endophytic fungi from the genera Cladosporium and Alternaria showed antibiosis capacity against Botrytis cinerea at the laboratory scale, which could potential biocontrol agents of pathogens in grapevine cultivation.

ABSTRACT The objective of this article is to examine samples of Super fuel from selected gas stations in the province of Guayas. The purpose is to obtain a characterization of this fuel to determine which is the best for motorcycles, thus seeking to improve its performance. The methodology used is quantitative, based on the collection and analysis of numerical data to answer research questions, since three samples were collected from the selected gas stations: Gómez Rendon, Portete and via Durán Tambo. These samples were sent to certified laboratories for evaluation according to the study parameters. The results obtained showed that the Portete gas station provides the best fuel quality. However, it is necessary to evaluate the possibility of outliers that may affect the validity of the study. Therefore, it is decided to apply Dixon's theorem to rule out any outlier data. Before that, a check is performed to determine whether the data set follows a normal distribution using the Minitab program. The results of the analysis conclude that none of the values obtained can be considered outliers. In conclusion, this project focuses on the evaluation of Super fuel samples from different gas stations to determine which one offers the best quality. This study provides valuable information to improve the performance of the fuel.

RESUMEN Este artículo tiene como objetivo examinar muestras de combustible Super de gasolineras seleccionadas en la provincia de Guayas. El propósito es obtener una caracterización de dicho combustible para determinar cuál es el mejor para motocicletas, buscando así mejorar su rendimiento. La metodología que se usa es la cuantitativa que se basa en la recopilación y análisis de datos numéricos para responder preguntas de investigación ya que se recolectaron tres muestras de las gasolineras seleccionadas: Gómez Rendón, Portete y vía Durán Tambo. Estas muestras fueron enviadas a laboratorios certificados para que realicen la evaluación de acuerdo con los parámetros del estudio. Los resultados obtenidos permitieron determinar que la gasolinera Portete provee la mejor calidad de combustible. Sin embargo, es necesario evaluar la posibilidad de que existan datos atípicos que puedan afectar la validez del estudio. Por lo tanto, se decide aplicar el teorema de Dixon para descartar cualquier dato atípico. Antes de eso, se realiza una verificación para determinar si el conjunto de datos sigue una distribución normal utilizando el programa Minitab. Los resultados del análisis concluyen que ninguno de los valores obtenidos puede ser considerado como dato atípico. En conclusión, este proyecto se enfoca en la evaluación de muestras de combustible Super de diferentes gasolineras para determinar cuál ofrece la mejor calidad. Este estudio proporciona información importante para mejorar el rendimiento de motocicletas al seleccionar el combustible adecuado.

RESUMEN. La investigación se centra en diseñar una estrategia para el desarrollo de la competencia investigativa en estudiantes universitarios de la carrera de Ingeniería Industrial de la Universidad Instituto Irapuato (UII). La metodología de enfoque cuantitativo es experimental, con grupo natural intacto y grupo con intervención. La intervención será llevar a la práctica el taller “Cómo hacer investigación en la ingeniería” y, posteriormente, aplicar una rúbrica evaluativa; los datos se analizan en Minitab Statistical Software utilizando procedimientos de prueba de hipótesis e intervalos de confianza para comparar las medias de las intervenciones. Los resultados del experimento de p-valor 0,013 evidencian un cambio significativo en la variable dependiente: competencia investigativa, logrando el diseño de la estrategia para el desarrollo de la competencia investigativa en estudiantes de la carrera de Ingeniería Industrial de la UII.

SUMMARY. The research focuses on designing a strategy for the development of research competence in university students of the Industrial Engineering degree at the UII. The quantitative approach methodology is experimental with an intact natural group and a group with intervention, where the intervention will be to put into practice the workshop “How to do Research in Engineering” to later apply an evaluative rubric, analyzing the data in Minitab Statistical Software using procedures hypothesis testing and confidence intervals to compare the means of the interventions. The results of the experiment with a p-value of 0,013 show a significant change in the dependent variable: research competence, achieving the design of the strategy for the development of research competence in students of the Industrial Engineering degree at the UII.

RESUMEN Se realizó un estudio de caracterización mineralógica en tres bocaminas de extracción, Esmeralda, Orión y Hércules, con el propósito de optimizar la tasa de recuperación de plomo-plata (Pb-Ag) mediante el proceso de flotación. Se evaluaron las variables dosificación de reactivo mezcla (AP-3418/AR-404), AR-242 y pH. En la bocamina Esmeralda, se utilizó una dosificación de 18 g/t de mezcla (AP-3418/AR- 404), 5 g/t de AR-242 con un pH óptimo de 11.5, que permitió recuperar un 81.99% de plomo con una calidad de 58.66% y 83.79% de plata con una calidad de 310.64 oz/t. En la bocamina Orión, se utilizó una dosificación de 30 g/t de (AP-3418/AR-404), 5 g/t de AR-242 con un pH óptimo de 10.5, que permitió recuperar 81.71% de plomo con un grado de 61.6% y 81.24% de plata con una ley de 85.39 oz/t, es decir, se alcanzaron valores óptimos. En la bocamina Hércules, se utilizó una dosificación de 30 g/t de (AP-3418/AR-404), 15 g/t de AR-242 y pH de 11.5, que permitió recuperar 82.4% de plomo con un grado de 54.12 y 80.88% de plata con una ley de 62.63 oz/t.

ABSTRACT A mineralogical characterization study to optimize lead-silver (Pb-Ag) recovery rate by flotation was conducted at three adits named Esmeralda, Orión, and Hércules. The variables investigated included the dosage of the reagent blend (AP-3418/AR-404), AR-242, and pH. At the Esmeralda adit, a recovery of 81.99% lead at a concentrate grade of 58.66% and 83.79% silver at a head grade of 310.64 oz/t was achieved using a dosage of 18 g/t reagent blend (AP-3418/AR-404), 5 g/t AR-242, and an optimum pH value of 11.5. At the Orión adit, a recovery of 81.71% lead at a concentrate grade of 61.6%, and 81.24% silver at a head grade of 85.39 oz/t were achieved using a dosage of 30 g/t reagent blend (AP-3418/AR-404), 5 g/t AR-242, and an optimum pH value of 10.5. Finally, at the Hércules adit, a recovery of 82.4% lead at a concentrate grade of 54.12%, and 80.88% silver at a head grade of 62.63 oz/t grade were achieved using a dosage of 30 g/t reagent blend (AP-3418/AR-404), 15 g/t AR-242, and a pH value of 11.5.

RESUMO O envelhecimento ativo se apoia em quatro pilares: saúde, segurança, participação e aprendizagem ao longo da vida. Esses pilares auxiliam os indivíduos na qualidade de vida ao longo do processo de envelhecimento. Objetivo: Analisar a efetividade do Programa Envelhecimento Ativo; identificar o perfil sociodemográfico dos participantes; identificar patologias predominantes na avaliação inicial; e verificar os resultados do programa após um ano de acompanhamento. Métodos: Trata-se de pesquisa quantitativa, de caráter transversal, exploratória, documentária e descritiva. Foram analisados os dados de 545 funcionários da Universidade de São Paulo que participaram do Programa do Envelhecimento Ativo do Hospital Universitário da Universidade de São Paulo (HU-USP) no período de 2015 a 2018. Os dados foram analisados pelo Programa Minitab. Na análise de dados, usou-se o Qui-quadrado para testar a associação entre os grupos. Já para medida contínua, utilizou-se o Teste T Pareado, para verificar se as médias eram diferentes. Nas análises, foi usado um período de confiabilidade de 95% e nível de relevância de 0,05. Resultados: Foram encontradas correlações estatisticamente expressivas no cruzamento de sexo com tabagismo; sexo com triglicérides; idade com fatores de risco para doenças cardiovasculares sendo que a faixa etária de 40–59 foi estatisticamente mais significativa; atividade física com prevalência de fatores de riscos para doenças cardiovasculares; e índice de massa corpórea inicial com o resultado após um ano. Conclusão: A pesquisa ampliou o conhecimento a respeito dos fatores de risco para doenças cardiovasculares e forneceu informações importantes para a continuidade do programa. saúde segurança Objetivo participantes acompanhamento Métodos Tratase Trata quantitativa transversal exploratória descritiva 54 HUUSP HU USP (HU-USP 201 2018 Minitab usouse usou Quiquadrado Qui quadrado grupos contínua utilizouse utilizou Pareado diferentes análises 95 005 0 05 0,05 Resultados tabagismo triglicérides 4059 40 59 40–5 significativa Conclusão 5 20 9 00 0,0 405 4 40– 2 0,

ABSTRACT Active aging is based on four pillars: health, safety, participation, and lifelong learning. These pillars help individuals improve their quality of life throughout the aging process. Objective: To analyze the effectiveness of the Active Aging Program; identify the sociodemographic profile of the participants; identify prevalent diseases in the initial evaluation; and assess the results of the program after one year of follow-up. Methods: This is a quantitative, cross-sectional, exploratory, desk research, and descriptive study. Data from 545 employees of University of São Paulo participating in the Active Aging Program of the University Teaching Hospital of the University of São Paulo (HU-USP) between 2015 and 2018 were analyzed using the Minitab Program. For data analysis, Pearson's chi-square test was used to determine the association between Groups A and B. For continuous measures, the paired t-test was used to verify differences in means, adopting a 95% confidence interval and significance level of 0.05. Results: Statistically significant correlations were found when crossing sex with smoking; sex with triglycerides; age with risk factors for cardiovascular diseases, being the age group 40–59 statistically more significant; physical activity with risk factors for cardiovascular diseases; and body mass index at program entry with the one-year result. Conclusion: The study expanded knowledge about risk factors for cardiovascular diseases and provided important information for the continuity of the program. health safety participation learning process Objective participants evaluation followup. followup follow up. up follow-up Methods quantitative crosssectional, crosssectional cross sectional, sectional cross-sectional exploratory research 54 HUUSP HU USP (HU-USP 201 analysis Pearsons Pearson s chisquare chi square B measures ttest t means 95 005 0 05 0.05 Results smoking triglycerides 4059 40 59 40–5 oneyear result Conclusion 5 20 9 00 0.0 405 4 40– 2 0.

Abstract This paper explores the use of novel lightweight concrete as an alternative material, focusing on Cellular Lightweight Foam Concrete (CLFC), renowned for its strength, low weight, thermal insulation, and sustainability. The study encompasses a thorough review of literature focusing on the evolution of lightweight concrete, experimental investigation including mix design variations and mechanical property analysis, statistical analysis using MINITAB software, SEM and EDS interpretation, and construction of model POD. Regression analysis was performed to investigate on the factors influencing compressive strength, revealing significant predictors such as cement, fly ash, water, and density, paving the way for enhanced concrete mixes. Characterization studies such as SEM and EDS were performed to analyse the formation of elements that contribute to the strength parameter. Moreover, the study underscores the potential of utilizing steam curing cycle to achieve early compressive strength in concrete mixes. Ultimately, the research aims to revolutionize construction practices by advocating for the widespread adoption of CLFC and innovative construction techniques to meet the demands of low-cost, eco-friendly housing. material CLFC, , (CLFC) weight insulation sustainability software interpretation POD cement ash water density mixes parameter Moreover Ultimately lowcost, lowcost cost, cost low-cost ecofriendly eco friendly housing (CLFC

Resumo A criação de bezerras é uma das atividades mais importantes na bovinocultura leiteira, visto que estas serão os animais de reposição do rebanho. Objetivou-se avaliar o efeito da estação de nascimento da bezerra no desenvolvimento na fase de cria e desempenho reprodutivo e produtivo. O experimento foi conduzido na Fazenda Experimental Glória, da Universidade Federal de Uberlândia. Foram avaliadas 74 bezerras nascidas de janeiro/2018 a março/2020, desde o primeiro dia de vida ao final da sua primeira lactação. Os animais foram categorizados de acordo com a estação de nascimento: primavera/verão (outubro a março) e outono/inverno (abril a setembro). Durante o aleitamento foi avaliado o peso dos animais nos dias: 0, 30, 60 após o nascimento e no desaleitamento. A temperatura retal, o escore de fezes, a ingestão de alimento e o comportamento animal foram monitorados diariamente. Na vida adulta foram avaliadas data da cobertura fértil, do parto e monitorada a produção de leite durante a primeira lactação. As variáveis analisadas foram: ganho de peso durante o aleitamento, ocorrência de doenças na fase de aleitamento, porcentagem de novilhas que pariram, idade ao primeiro parto e média de produção de leite da primeira lactação de acordo com a estação de nascimento. As variáveis contínuas foram analisadas por análise de variância e as variáveis binomiais por regressão logística no programa MINITAB. As bezerras nascidas na estação outono/inverno apresentam maior peso aos 30 dias, porém esta diferença foi compensada durante o aleitamento, não interferindo no desempenho reprodutivo e produtivo. leiteira rebanho Objetivouse Objetivou se produtivo Glória Uberlândia 7 janeiro2018 janeiro 2018 janeiro/201 março2020 março 2020 março/2020 primaveraverão primavera verão outubro outonoinverno outono inverno abril setembro. setembro . setembro) dias 0 6 desaleitamento retal fezes diariamente fértil pariram MINITAB 3 janeiro201 201 janeiro/20 março202 202 março/202 janeiro20 20 janeiro/2 março20 março/20 janeiro2 2 janeiro/ março2 março/2 março/

Abstract Raising heifers is one of the most important activities in dairy farming because heifers eventually replace the herd. This study was performed to evaluate how the calf’s birth season affects its early development and its reproductive and productive performance. The experiment was conducted at the Glória Experimental Farm of the Federal University of Uberlândia, Minas Gerais, Brazil. In total, 74 female calves born from January 2018 to March 2020 were evaluated from the first day of life to the end of their first lactation. The animals were classified according to their season of birth: spring/summer (October–March) or fall/winter (April–September). During the initial phase of life, the animals’ weights were assessed on days 0, 30, and 60 after birth and at weaning. The rectal temperature, fecal score, feed intake, and animal behavior were recorded daily. In the mature phase of life, the dates of conception and calving were evaluated, and milk production during the first lactation was monitored. The following variables were analyzed according to season of birth: weight gain and occurrence of diseases during the initial phase, percentage of heifers that calved, age at first calving, and average milk production during the first lactation. Continuous variables were analyzed by analysis of variance, and binomial variables were analyzed by logistic regression using the Minitab software program. Calves born in fall/winter had a higher weight at 30 days; however, this difference was compensated for during the initial phase and did not interfere with reproductive and productive performance. herd calfs calf s performance Uberlândia Gerais Brazil total 7 201 202 springsummer spring summer October–March OctoberMarch October (October–March fallwinter fall winter April–September. AprilSeptember April–September . April September (April–September) 0 6 weaning temperature score intake daily monitored calved variance program 3 however 20 (April–September 2

Alzheimer's disease (AD) is the most common cause of dementia worldwide. Fifty million people today are affected by this disease globally. AD has had a tremendous impact on the affected individual, caregiver, and society, in both developed and developing nations. Donepezil—chitosan-gold nanocomposite (Donz-CS-AuNPs) was prepared by co-precipitation technique. Placket-Burman experimental design was used in this work to estimate the effect of the three independent variables (concentration of chitosan, gold, and donepezil) on the dependent variables (loading efficiency, and particle size) by using Minitab 18.1 software. The quantities for the independent variables used were: 10 and 40 mg of donepezil, 24.6 and 73.8 mg of gold, and 500 and 1500 mg of chitosan. The Donz-CS-AuNPs were characterized using energy dispersive X-ray (EDX) analysis, X-ray diffraction (XRD), scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), UV-Vis spectroscopy and release study. The results of EDX showed strong signals of Au (1.5–2, 2–2.5 and 9.5–10 keV), which confirmed the specific gold peaks from the Donz-CS-AuNPs. The XRD pattern of Donz-CS-AuNPs nanocomposites showed the existence of AuNPs peak at 2θ= 38.2°, 43.8° and 64.5°. The SEM images demonstrated spherical shapes of the AuNPs. In the in vitro release study, the release increased steeply and reached 75% after 1440 min. Alzheimers Alzheimer s (AD worldwide globally individual caregiver society nations Donepezilchitosangold Donepezil chitosan DonzCSAuNPs Donz CS (Donz-CS-AuNPs coprecipitation co precipitation technique PlacketBurman Placket Burman concentration donepezil loading efficiency size 181 18 1 18. software 4 246 24 6 24. 738 73 8 73. 50 150 Xray X ray (EDX analysis XRD, , (XRD) SEM, (SEM) FTIR, FTIR (FTIR) UVVis UV Vis study 1.5–2, 152 5 2 (1.5–2 225 2–2. 9510 9 9.5–1 keV, keV keV) DonzCSAuNPs. 2θ θ 382 38 38.2° 438 43 43.8 645 64 64.5° 75 144 min 7 15 (XRD (SEM (FTIR 1.5–2 (1.5– 22 2–2 951 9.5– 3 38.2 43. 64.5 14 1.5– (1.5 2– 95 9.5 38. 64. 1.5 (1. 9. 1. (1 (

Resumo Introdução/Objetivos: No final de 2019, autoridades relataram sobre pacientes com pneumonia de causa desconhecida. A etiologia identificada foi um novo coronavírus (SARS-CoV-2), apontando que isolamento social e uso de máscaras faciais seriam úteis para a prevenção do quadro. Desse modo, o estudo objetivou identificar a influência sociodemográfica na adesão às medidas de contenção à pandemia de COVID-19. Método: Estudo transversal e quantitativo realizado por meio de plataforma online, com uma amostra de 291 indivíduos, a quem foram enviadas mensagens instantâneas, juntamente com os dois questionários, o primeiro contendo questões sociodemográficas e o segundo referente aos possíveis fatores que influenciam na adesão às medidas de contenção à pandemia. Ao final da coleta de dados foram realizadas as análises descritivas com os dados da caracterização sociodemográfica dos participantes. Foram utilizados o Minitab 16 e Bioestat 5.0 para análise dos testes qui-quadrado e G e considerado nível de significância 0,05 e resíduo maior que 1,96 para efeito de análise. Resultados: Amostra de 291 indivíduos, com predomínio do sexo feminino (67,9%), da faixa etária de 18 a 25 anos (31,4%), de participantes com ensino superior completo (47,1%), residentes na região Sudeste (93,5%) e de indivíduos que trabalham no setor terciário (47,2%). No que tange ao uso de máscaras encontrou-se significância estatística nas variáveis grupo de risco, idade, setor econômico e ensino superior incompleto. Conclusão: O estudo evidenciou expressiva adesão ao isolamento social entre participantes com mais de 60 anos, os que possuem entre seis e 10 cômodos na residência, profissionais do setor terciário e indivíduos que se informam por jornais, revistas, rádios e outros meios. Quanto à adesão ao uso de máscaras faciais destacaram-se participantes com ensino superior completo, pertencimento ao grupo de risco e crença na eficácia do EPI. Desse modo, demonstrou-se a importância do envolvimento da população no enfrentamento de pandemias.

Abstract Introduction and goals: At the end of 2019, authorities reported people with pneumonia without apparent reason. This way, the agent identified a new coronavirus (SARS-CoV-2), demonstrating that a great solution would be social isolation and the use of surgical masks. This research has the objective to identify the socio-demographic influence in joining the measures to prevent the spread of the virus and contain the pandemic of COVID-19. Methods: Transversal and quantitative research was done through an online platform, gathering information through instant messages and two questionnaires completed by 291 participants. The first questionnaire contained sociodemographic questions and the second referred to possible reasons that affect the acceptance of mandates to prevent the virus. A descriptive analysis was made afterward, using Minitab 16 and Bioestat 5.0 to analyze chi-squared and G tests, and the importance level of 0.05 and more than 1.96 as a residue to calculate was considered. Results: A sample of 291 participants, which contained more females than males (67.9%), people between 18 and 25 years old (31.4%), people that finished high school (47.1%), the population of Southeast (93.5%) and people that work in the third sector (47.2%). When related to the use of masks, there was a significant variance in groups of risk, age, economic sector, and incomplete high school. Conclusion: The research showed a great number of people isolating themselves. Most of them were more than 60 years old, people who had between 6 to 10 rooms at home, professionals from the third sector, and people who got informed by the media. Regarding the use of the masks, the greatest participants were people who finished high school, groups at risk, and people who trusted the masks’ efficiency. This way, it was possible to realize the importance of involving the population to combat the pandemic.

Resumen El objetivo es presentar un modelo de balanceo de cargas de trabajo, bajo el enfoque Business Process Management (BPM), a través de un estudio de caso en el proceso estocástico, multiobjetivo y complejo de análisis de créditos comerciales en un banco, que tiene problemas en la asignación de los recursos, puesto que algunos están recargados con relación a otros, y no se cumple la promesa de valor, en cuanto al tiempo de respuesta al cliente, ante una solicitud de crédito. La metodología aplicada incluye teoría de colas, con herramientas de control de producción y análisis de operaciones, tales como diagramas y caracterización de redes de Jackson, así como la simulación. También se encontró que los métodos heurísticos y de programación lineal no aplican para un proceso de esta complejidad, se realizaron análisis estadísticos a las diferentes variables de entrada con el programa computacional Minitab 21.2®; se usó el software de simulación de eventos discretos SIMIO® para modelar la situación actual, en pro de evidenciar las causas de la problemática; y, al buscar el máximo desempeño del indicador de uso de capacidad instalada, se observó deterioro en las otras métricas como el tiempo de ciclo y el WIP (Trabajo en Progreso, por sus siglas en inglés), por lo anterior, se buscó un escenario que no necesariamente fuera el óptimo, pero que en balance para todos los indicadores tuviera un resultado aceptable con el desempeño esperado. Este estudio es relevante para el sector de servicios financieros, pues se logra mejoras significativas en los indicadores clave de desempeño de un proceso complejo.

Abstract The objective is to present a workload balancing model within the Business Process Management (BPM) framework through a case study of the stochastic, multi-objective, and complex process of analyzing commercial credit applications in a bank. The bank grapples with resource allocation problems-some resources are overloaded while others are underutilized, resulting in suboptimal response times for credit applicants. The applied methodology encompasses queuing theory, production control tools, and operations analysis techniques such as diagrams and characterization of Jackson networks, along with simulation. It was observed that heuristic and linear programming methods are unsuitable for this process due to its complexity. Consequently, statistical analyses were conducted on various input variables using the Minitab 21.2® software. The SIMIO® discrete event simulation software modeled the current situation to identify the root causes of the problem. The objective was to maximize installed capacity utilization while avoiding deterioration in metrics like cycle time and Work in Progress (WIP). Therefore, a scenario was sought that, while not necessarily optimal, achieved a balance among all indicators, delivering acceptable results in terms of expected performance. This study holds significance for the financial services sector, as it leads to substantial improvements in key performance indicators for a complex process.

Resumo O objetivo é apresentar um modelo de balanceamento de carga de trabalho, sob a abordagem Business Process Management (BPM), através de um estudo de caso no processo estocástico, multiobjetivo e complexo de análise de crédito comercial em um Banco. Tal banco apresenta problemas na alocação de recursos uma vez que uns estão sobrecarregados relativamente a outros e a promessa de valor não é cumprida em termos de tempo de resposta ao cliente perante um pedido de crédito. A metodologia aplicada inclui teoria de filas, com ferramentas de controle de produção e análise de operações como diagramas e caracterização de redes Jackson, bem como simulação. Verificou-se também que métodos heurísticos e de programação linear não se aplicam a um processo desta complexidade. Foram realizadas análises estatísticas nas diferentes variáveis de entrada, com o programa Minitab 21.2®, adicionalmente o software de simulação de eventos discretos simio® foi utilizado para modelar a situação atual a fim de revelar as causas do problema. Por meio da busca pelo desempenho máximo do indicador de uso de capacidade instalada, foi observada deterioração em outras métricas como tempo de ciclo e wip (Work in Progress). Portanto, buscou-se um cenário que não fosse necessariamente o ideal, mas que em equilíbrio para todos os indicadores tivesse um resultado aceitável com o desempenho esperado. Este estudo é relevante para o setor dos serviços financeiros, uma vez que são alcançadas melhorias significativas nos principais indicadores de desempenho de um processo complexo.

Resumen En las últimas dos décadas, el precio del agave en los estados con denominación de origen del tequila ha sido objeto de incertidumbre. Esta investigación (secuencial mixta) identifica las variables que afectan su valor comprobando la causa del problema. Con el software Minitab se aplica el análisis de correlación de Pearson a las variables más importantes y los métodos predictivos de series de tiempo para pronosticarlas. El análisis de correlación comprobó que la producción de agave no está correlacionada con su precio, en contraste con la producción de tequila, su exportación y los ingresos por su exportación. Desde 2016, el precio y producción de agave redujeron sistemáticamente su promedio anual de crecimiento hasta alcanzar niveles negativos en 2021, contrario a la producción, exportación de tequila y sus ingresos (las cinco variables mantienen esta tendencia para los próximos diez años). Se demuestra que el problema del precio del agave al cierre de la última década no se debe al desequilibrio de su oferta, infiriendo que el oligopolio de empresas líderes de la agroindustria del tequila en México controla su valor.

Abstract In the last two decades, the price of agave in states holding Designation of Origin of Tequila (DOT) status has been subject to uncertainty. This mixed sequential investigation identifies the variables that affect its value, verifying the cause of the problem. Using Minitab software, Pearson’s correlation analysis is applied to the most important variables and time-series predictive methods are applied to forecast them. The correlation analysis verified that the production of agave is not correlated with its price, in contrast to the production of tequila, its export and the income from its export. Since 2016, the price and production of agave systematically reduced its annual average growth until reaching negative levels in 2021, contrary to the production, export of tequila and its income (the five variables maintain this trend for the next 10 years). It is shown that the problem of the agave price at the end of the last decade is not due to imbalances in its supply, suggesting that the oligopoly of leading companies of the tequila agroindustry in Mexico controls its value.

[Objective] The objective of this study was to evaluate the short-term response of four different odor mitigation measures in a homogenization tank of a university WWTP. [Methodology] Aeration, addition of lime, addition of iron sulfate, and addition of the commercial product BiOWiSH® Odor were implemented over a study period equal to four hydraulic retention times. Monitoring was conducted for the influent water and within the tank for each period, including a baseline measurement for comparison. pH, oxidation-reduction potential, and dissolved oxygen were measured in triplicates every 30 minutes, along with the concentration of dissolved sulfide. An odor perception survey was administered to WWTP visitors, evaluating intensity, offensiveness, and character with a total of 15 surveys per period. Differences between the mitigation measures and baseline were determined using t-student tests for quantitative data and Mood's medians for qualitative data. Minitab 2019 was used with a confidence level of 95%. [Results] All the mitigation measures significantly decreased the concentration of dissolved sulfide in the tank. Aeration prevented oxygen depletion, reducing conditions, and acid fermentation, favoring the oxidation of odorous compounds. It was the only studied mitigation measure that led to a reduction in intensity and offensiveness of the odor. [Conclusions] The application of aeration induced changes in the tank's behavior and odor perception, confirming its effectiveness. The addition of iron sulfate, lime, and BiOWiSH® did not generate significant changes in odor perception.

[Objetivo] El objetivo de este estudio fue evaluar la respuesta a corto plazo de cuatro diferentes medidas de mitigación de olores en un tanque de homogeneización de una PTAR universitaria. [Metodología] Se aplicaron las medidas de aireación, adición de cal, adición de sulfato de hierro y adición del producto comercial BiOWiSH® odor; durante cuatro tiempos de retención hidráulico. Se monitoreó el afluente y la unidad en cada periodo, utilizando una línea base como comparación de las medidas. Se midió por triplicado cada 30 min el potencial de Hidrógeno, potencial de oxidación reducción, oxígeno disuelto y la concentración de sulfuro disuelto. Se aplicó una encuesta de percepción de olores a visitantes de la PTAR evaluando intensidad, ofensividad y carácter con un total de 15 encuestas por periodo de monitoreo. Se determinaron diferencias entre medidas de mitigación y línea base con pruebas t-student (datos cuantitativos) y medianas de Mood (datos cualitativos). Se utilizó Minitab2019 y un límite de confianza de 95%. [Resultados] Todas las medidas de mitigación disminuyeron significativamente la concentración de sulfuro disuelto en la unidad. La medida aireación evitó el agotamiento de oxígeno, régimen reductivo y fermentación ácida, favoreciendo la oxidación de odorantes, además fue la única medida de mitigación estudiada que generó una reducción en la intensidad y ofensividad del olor. [Conclusiones] La aplicación de aireación generó un cambio en el comportamiento de la unidad y la percepción de olor, confirmando su efectividad. La adición de sulfato de hierro, cal y BiOWiSH® no generaron cambios significativos en la percepción de olor.

RESUMEN La investigación se desarrolla en el Centro de Inmunología Molecular (CIM), institución biotecnológica cubana dedicada a la investigación básica, el desarrollo y la fabricación de productos para el tratamiento contra el cáncer y otras enfermedades autoinmunes. En este artículo se aborda como problemática la deficiente gestión de los inventarios en las empresas, como consecuencia en gran medida de la inexistencia de procedimientos que permiten el buen desempeño del proceso logístico. El objetivo de la investigación es implementar el procedimiento de gestión de inventarios, el cual permite planificar, gestionar y controlar los inventarios necesarios sin afectar el nivel de los servicios, basado en el análisis de indicadores, descripción de los flujos logísticos y la aplicación del modelo de referencia de los inventarios (MRInv). Para ello, se utilizaron diferentes técnicas y herramientas, como entrevistas, observación directa, encuestas, análisis documental, software estadístico Minitab y el método ABC. Como resultado se obtuvo la aplicación del procedimiento para gestionar los inventarios, que consta de diez pasos que permiten realizar la gestión de manera organizada.

ABSTRACT The research was carried out at the Molecular Immunology Center (CIM), a Cuban biotechnological institution dedicated to basic research, development, and manufacture of products for the treatment of cancer and other autoimmune diseases. The research problem addressed the poor management of inventories in companies, which is largely a consequence of the lack of procedures that enable the good perfor- mance of the logistics process. The objective of the research was the implementation of the inventory management procedure aimed at planning, managing, and controlling the necessary inventories without affecting the quality of the services, based on the analysis of indicators, description of logistics flows, and application of the Inventory Reference Model (MRInv). Different techniques and tools-including interviews, direct observation, surveys, documentary analysis, Minitab statistical software, and ABC analysis-were used. The result was the implementation of the inventory management procedure, which consisted of 10 steps that allow management to be carried out in an organized manner.

Resistant infectious microorganisms are causing a worldwide emerging problem, called antimicrobial resistance. To avoid this outbreak, new antimicrobial technologies are necessary. Silver nanoparticles (AgNPs) are known for their antibacterial properties and several studies have focused on their synthesis, characterization, and biological assays. One possibility to synthesize AgNPs is through gamma radiation, known as radiolytic synthesis. This work focuses on the radiolytic synthesis of AgNPs capped into a mesoporous silica nanoparticle aiming at an antimicrobial application. The variants of the radiolytic synthesis, which may influence the AgNPs formation, were studied and statistically compared by Design of Experiments Factorial Design in Minitab Software. The Ag content is statically dependent on dose, volume, and pH, as well as on two parameters interaction: [Ag+]-pH and [Ag+]-volume pH interaction. Transmission electron microscopy and nitrogen adsorption analyses indicated the presence of subnanometric AgNPS located inside the mesopores. Silver nanoagglomerates were also found by transmission electron microscopy, which could be formed by silver oxides, as shown in X-ray photoelectron spectroscopy. AgNPs reduce the specific surface area of the silica nanoparticle, while the matrix morphology remains. The nanocomposites presented preliminary biocompatibility observed in in vitro biological assay using fibroblasts, which support their application in biological systems as antimicrobial substitutes. problem resistance outbreak necessary (AgNPs characterization assays radiation formation Software dose volume interaction Ag+pH AgpH Ag+ Ag+volume Agvolume mesopores oxides Xray X ray spectroscopy remains fibroblasts substitutes