Abstract Only within the last decade, the works of Uruguay an Engineer Eladio Dieste (1917-2000) have been gaining international academic dissemination, one of whose main contributions in the realm of formal-structural conception within architecture and civil engineering reside in the iterative development of the structural typology of the gaussian vault shells in reinforced brickwork. However, there is not an established definition for this typology’s architectural geometry. Also, there is hardly any evidence of how such shells were designed. Therefore, the main objective, of this paper is to demonstrate the underlying geometric relationships in the discontinuous gaussian vault shells designed and built by Eladio Dieste in reinforced brickwork, the dominant typological variation within the object of study. This analysis was carried out by means of the parametric modeling and the polynomial regression of selected case studies from the primary sources, since such computational tools allow for the proper geometrical management of formally complex geometries. The expected contributions of this study reside in the deepening of the understanding of the relationship between the design process and the geometry of the object of study, as well as the understanding of the geometrical conformation of the structural typology conceived by Eladio Dieste. decade 19172000 1917 2000 (1917-2000 dissemination formalstructural formal brickwork However typologys s Also Therefore objective sources geometries 1917200 191 200 (1917-200 191720 19 20 (1917-20 19172 1 2 (1917-2 (1917- (1917 (191 (19 (1 (

Resumo Apenas na última década, a obra do engenheiro Uruguaio Eladio Dieste (1917-2000) vem ganhando disseminação acadêmica internacional, sendo que uma de suas principais contribuições para a concepção formal-estrutural na arquitetura e engenharia civil foi o desenvolvimento iterativo da tipologia estrutural das abóbadas gaussianas, cascas de dupla-curvatura estruturadas em cerâmica armada. Entretanto, não há registros de uma definição estabelecida para a geometria arquitetônica destas tipologias estruturais. Tampouco existem evidências concretas acerca da concepção e desenvolvimento projetual destas estruturas. Por conseguinte, o objetivo deste artigo é evidenciar as relações geométricas subjacentes nas abóbadas guassianas descontínuas projetadas e construídas por Eladio Dieste em cerâmica armada, a variação dominante desta tipologia estrutural. Esta análise foi conduzida através da modelagem paramétrica e da regressão polinomial de estudos de caso selecionados a partir de fontes primárias originais, justamente por estas ferramentas computacionais permitirem o correto manejo de geometrias tidas como formalmente complexas. A contribuição esperada para esta pesquisa reside em aprofundar o entendimento entre a relação do processo de projeto e a geometria resultante no objeto de estudo, assim como o entendimento da conformação geométrica desta tipologia estrutural desenvolvida por Eladio Dieste. década 19172000 1917 2000 (1917-2000 internacional formalestrutural formal gaussianas duplacurvatura dupla curvatura armada Entretanto estruturais estruturas conseguinte originais complexas estudo 1917200 191 200 (1917-200 191720 19 20 (1917-20 19172 1 2 (1917-2 (1917- (1917 (191 (19 (1 (

Resumen Costa Rica por las características de su territorio, puede ofrecer en su actividad turística, servicios modernos, creativos e innovadores, basados en el conocimiento, que utilizan alta tecnología y/o cuentan con mano de obra calificada. Datos del BCCR, indican que el porcentaje del aporte en la última década de la actividad turística al PIB, fue de aproximadamente 5%, por ello, se presenta una ruta para un desarrollo sostenible e inclusivo, que posibilite empleos de calidad y favorezca una mejor redistribución de la riqueza entre los habitantes de Costa Rica, enmarcada con el compromiso de los ODS, un adecuado control de las variables macroeconómicas del mercado interno e internacional; y con una modificación de la ley general de turismo, con el propósito de que exista un ente rector de la actividad que posibilite una mejor coordinación y gestión de la actividad y su aporte al desarrollo.

Resumo A Costa Rica, devido às características de seu território, pode oferecer em sua atividade turística serviços modernos, criativos e inovadores, baseados no conhecimento, que utilizam alta tecnologia e/ou contam com mão de obra qualificada. Dados do BCCR indicam que a porcentagem da contribuição da atividade turística para o PIB na última década foi de aproximadamente 5%. Portanto, apresenta-se uma rota para um desenvolvimento sustentável e inclusivo, que possibilite empregos de qualidade e favoreça uma melhor redistribuição da riqueza entre os habitantes da Costa Rica, alinhada com o compromisso dos ODS, um controle adequado das variáveis macroeconômicas do mercado interno e internacional; e com uma modificação da lei geral de turismo, com o propósito de existir uma entidade reitora da atividade que permita um melhor coordenação e gestão da atividade e sua contribuição para o desenvolvimento.

Summary Costa Rica, due to the characteristics of its territory, can offer modern, creative and innovative services in its tourism, based on knowledge, that use high technology and/or have qualified labor. Data from the BCCR indicates that, in the last decade, the percentage of tourism contribution to GDP was approximately 5%, therefore, a route is presented for sustainable and inclusive development, which enables quality jobs and promotes better redistribution of wealth among the inhabitants, framed with the commitment to the SDGs, adequate control of the macroeconomic variables of the domestic and international market; and changing the general tourism law, with the aim to have an activity governing body oriented to better coordination and management and its contribution to development.

BACKGROUND. Adverse events are common, and impact patients and healthcare systems negatively. Large international systems investigate adverse events at length, but South African data are lacking. OBJECTIVES. To classify all adverse events that have occurred in our department over the last decade. METHODS. Ten years of data from a prospectively collated electronic medical record system were analysed for adverse events. All admitted patients were included. Duplicate entries and those that did not describe adverse events were excluded. RESULTS. The study period was from December 2012 to January 2023. There were 52 835 distinct admissions covering 321 385 inpatient days. After categorisation, a total of 14 537 adverse events were captured, giving an adverse event rate of 22%. Adverse events were categorised into four groups. Of the total, 8 027 events were clinical care related, 3 106 were pathology related, 2 662 were system related and 442 miscellaneous. A total of 300 were excluded. Clinical care-related adverse events comprised 57.3% of the total number. Of those, adverse events related to indwelling devices (32.4%), iatrogenic injuries (12.5%) and intravenous therapy administration (12.5%) contributed most. Pathology-related adverse events contributed 21.4% of the total, of which wound sepsis (29.5%), anastomotic leak (15.1%) and nosocomial pneumonia (14.4%) were the most common. There was a general downward trend in reported adverse events from 2016 to 2022. CONCLUSION. Adverse events are common, and their aetiology is multifactorial. A sustained and multi-faceted approach is needed to address the challenge they pose.

Este paper discute determinados recortes de uma pesquisa de mestrado em andamento. O presente trabalho tem o objetivo de analisar perfis de Instagram de mulheres defensoras das armas de fogo como instrumento de autodefesa e mapear as redes que formam. O fenômeno do ativismo feminino “pró-armas” está interligado à ascensão da nova direita, ao sentimento de insegurança e de descrédito em relação às instituições estatais, além do lobby armamentista. Tanto na política institucional quanto na sociedade civil são notórios os discursos de mulheres que representam o uso da arma de fogo como estratégia de autodefesa e também como ferramenta de empoderamento feminino. Consonante a isso, fontes de pesquisa atestam o crescimento significativo das fabricantes brasileiras de armas leves na última década no mercado de segurança internacional. A pesquisa, de caráter qualitativo, se baseia em observação etnográfica oculta em ambiente digital e em Análise de Rede Social (ARS) em fase inicial. Os materiais utilizados foram perfis de Instagram das atrizes e organizações sociais de maior circulação no meio da autodefesa armada feminina. Os resultados têm demonstrado: a articulação de símbolos originalmente feministas de empoderamento a velhos signos de feminilidade hegemônica; propostas de autodefesa armada para as mulheres como estratégia frente à violência contra a mulher; e um paralelo entre o crescimento do mercado armamentista e os perfis de ativismo feminino “pró-armas”, devido aos patrocínios às iniciativas das mulheres.

This paper discusses certain excerpts from an ongoing master's research. The present work aims to analyze Instagram profiles of women defenders of firearms as an instrument of selfdefense and to map the networks they form. The phenomenon of pro-gun female activism is interconnected with the rise of the new right, the feeling of insecurity and discredit in relation to state institutions, as well as the gun lobby. Both in institutional politics and in civil society, the discourses of women who represent the use of firearms as a strategy of self-defense and also as a tool for female empowerment are notorious. In line with this, research sources attest to the significant growth of Brazilian manufacturers of small arms in the last decade in the international security market. The research, of a qualitative nature, is based on ethnographic hidden observation in digital environment and on Social Network Analysis (SNA) in the initial phase. The materials used were Instagram profiles of the actresses and social organizations with the greatest circulation in the midst of female armed self-defense. The results have demonstrated: the  articulation of originally feminist symbols of empowerment with old signs of hegemonic femininity; proposals for armed self-defense for women as a strategy against violence against women; and a parallel between the growth of the arms market and the profiles of pro-gun female activism, due to sponsorships of women's initiatives.

En este artículo se discuten algunos extractos de una investigación de maestría en curso. El presente trabajo tiene como objetivo analizar los perfiles de Instagram de mujeres defensoras de armas de fuego como instrumento de autodefensa y mapear las redes que conforman. El fenómeno del activismo femenino pro-armas está interconectado con el ascenso de la nueva derecha, el sentimiento de inseguridad y descrédito en relación con las instituciones estatales, así como con el lobby de las armas. Tanto en la política institucional como en la sociedad civil son notorios los discursos de las mujeres que representan el uso de las armas de fuego como estrategia de autodefensa y también como herramienta de empoderamiento femenino. En línea con esto, fuentes de investigación atestiguan el importante crecimiento de los fabricantes brasileños de armas pequeñas en la última década en el mercado de la seguridad internacional. La investigación, de carácter cualitativo, se basa en la observación etnográfica oculta en un entorno digital y en el Análisis de Redes Sociales (ARS) en la fase inicial. Los materiales utilizados fueron los perfiles de Instagram de las actrices y las organizaciones sociales de mayor circulación en medio de la autodefensa armada femenina. Los resultados han demostrado: la articulación de símbolos de empoderamiento originalmente feministas con viejos signos de feminidad hegemónica; propuestas de autodefensa armada de las mujeres como estrategia contra la violencia hacia las mujeres; y un paralelismo entre el crecimiento del mercado armamentístico y los perfiles de activismo femenino pro-armas, debido al patrocinio de iniciativas de mujeres

RESUMEN: La importancia y relevancia de los cursos e-learning en medicina y ciencias de la salud ha aumentado significativamente en la última década. A pesar de ello, existen pocas experiencias docentes publicadas de cursos de histología e-learning en la literatura a nivel mundial. El curso de histología que diseñamos se estructuró en la plataforma Moodle, y los contenidos se propusieron en formato síncrono (zoom) y asíncrono (grabaciones). También incluimos el uso de herramientas gratuitas de microscopía virtual. Este estudio tuvo como objetivo investigar el impacto de un curso de histología e-learning en la satisfacción y el rendimiento de los estudiantes de medicina, enfermería y obstetricia. La muestra incluyó 424 estudiantes chilenos de medicina, enfermería y obstetricia de dos cohortes. Se aplicó una encuesta tipo Likert al final del curso. Se realizó un análisis exploratorio y una regresión por mínimos cuadrados ordinarios. En este estudio, presentamos una experiencia positiva de un curso de e-learning de histología. El análisis factorial exploratorio reveló tres factores principales relacionados con la "satisfacción sobre el aprendizaje e-learning", "clases presenciales versus clases virtuales" y el "diseño del curso y la calidad de la enseñanza". También encontramos que existía una relación positiva y significativa entre las percepciones de los estudiantes sobre la adaptación del curso de histología tradicional (presencial) a un formato e-learning y su rendimiento académico. Nuestro estudio muestra que los cursos de histología e-learning que integran clases teóricas y sesiones prácticas pueden ser una valiosa herramienta de enseñanza. Los responsables de la elaboración de planes de estudios y los profesores de histología deben tener en cuenta las limitaciones y ventajas de este tipo de enseñanza y sugerimos incorporar estos tres factores al diseño y la evaluación de los cursos de histología en línea.

SUMMARY: The importance and relevance of e-learning courses in medicine and health sciences has increased significantly in the last decade. Despite this, there are few published teaching experiences of e-learning histology courses in the literature worldwide. The histology course we designed was structured on the Moodle platform as a learning management system, and the content was proposed in a synchronous (zoom) and asynchronous (recordings) format. We also included the use of free virtual microscopy tools. This study aimed to investigate the impact of an e-learning histology course on the satisfaction and performance of medical, nursing and midwifery students. The sample included 424 Chilean medical, nursing, and midwifery students from two cohorts. A Likert-type survey was administered at the end of the course. We performed exploratory analysis and ordinary least squares regression. In this study, we present a positive experience of an e-learning histology course. Exploratory factor analysis revealed three main factors related to "e- learning satisfaction", "in-person class activities", and "course design and teaching quality". We also found that there was a positive and significant relationship between students' perceptions of the adaptation of the traditional (face-to-face) histology course into an e-learning format and their academic performance. Our study shows that e-learning histology courses that integrate lectures and practical sessions can be a valuable teaching method for learning histology. Curriculum developers and teachers need to consider the limitations and advantages of this type of teaching and incorporate these three factors into the design and assessment of e-learning histology courses.

Abstract Introduction Reforestation and restoration of forest ecosystems are increasingly difficult with climate change. Objective Define seed transfer zones for reforestation in the Monarch Butterfly Biosphere Reserve and the ‘Sembrando Vida’ program in the Meseta Purépecha to mitigate climate change. Materials and methods Maps were generated to visualize where the ideal climate conditions for reforestation are projected to occur (RCP 4.5 scenario, 2050) at different sites using seedlings collected in delimited areas under a reference climate (1961-1990). A climate zone system was used (based on the temperature of the coldest month and an aridity index) and layers of suitable climatic habitat for Pinus pseudostrobus and Abies religiosa for the reference (1961-1990) and projected (2060 decade) period. Results and discussion The areas to be reforested will be warmer in the future, requiring seed from sites, on average, 3 °C warmer. A reduction of approximately 50 % of the area of climatically favorable habitat for P. pseudostrobus and A. religiosa was estimated. This reduction occurs at the lower altitudinal limit called the 'xeric limit’; therefore, it will be necessary to replace them with species adapted to warmer sites. Conclusions Moving seed sources from warmer (+3 °C) and drier sites to currently wetter and cooler planting sites is recommended. This provides a useful tool for deciding the seed source under adaptive forest management facing climate change.

Resumen Introducción La reforestación y restauración de los ecosistemas forestales son cada vez más difíciles en el contexto del cambio climático. Objetivos Definir zonas de transferencia de semillas para reforestación en la Reserva de la Biosfera Mariposa Monarca y el programa ‘Sembrando Vida’ en la Meseta Purépecha, para compensar el cambio climático. Materiales y métodos Se generaron mapas para visualizar dónde se predicen las condiciones climáticas idóneas para la reforestación con plántulas de semilla colectada en zonas delimitadas bajo un clima de referencia (1961-1990) que se proyecta ocurrirá (escenario RCP 4.5, 2050) en sitios distintos. Se utilizó una zonificación climática (basada en la temperatura del mes más frío e índice de aridez) y capas de hábitat climático propicio para Pinus pseudostrobus y Abies religiosa del periodo de referencia (1961-1990) y proyectado (década 2060). Resultados y discusión Las áreas por reforestar serán más cálidas en el futuro, por lo que se requiere semilla de sitios, en promedio, 3 °C más cálidos. Se estimó una reducción de aproximadamente 50 % de la superficie del hábitat climático propicio de P. pseudostrobus y A. religiosa. Tal reducción ocurre en el límite inferior altitudinal denominado ‘límite xérico’, por lo que será necesario el reemplazo de estas por especies adaptadas a sitios más cálidos. Conclusiones Se recomienda el traslado de las fuentes de semillas de lugares más cálidos (+3 °C) y secos a sitios de plantación actualmente más húmedos y fríos. Este enfoque proporciona una herramienta útil para decidir la fuente de semilla bajo un manejo forestal adaptativo ante el cambio climático.

Resumo A última década mostrou à sociedade mundial - em especial a sociedade sul-americana - os grandes desafios aos quais as democracias estarão submetidas no século XXI. Entre as diversas ameaças observadas no ciberespaço estão as denominadas campanhas de desinformação e as interferências híbridas. Diante disso, esse novo meio digital de sociabilidade da informação tem provocado sérios danos aos pilares democráticos dos Estados, pois a desinformação e as informações falsas têm virado recurso no debate político. Isso posto, o artigo buscará analisar a construção de processos cooperativos na área de segurança e defesa cibernética entre os países sul-americanos entre 2012 e 2020 e seus efeitos na proteção da democracia e do Estado de direito. Defende-se que, devido à dinâmica transfronteiriça do mundo digital e do disseminado alcance de suas ações e consequências, a busca por uma solução a essas demandas perpassa um processo de aprofundamento da cooperação estatal no qual as estratégias de política externa dos Estados são fundamentais para a construção de uma resposta efetiva a esse tipo de ameaça à democracia em âmbito internacional. Nessa perspectiva, compreende-se a interdependência entre os Estados nessa esfera e adota-se uma concepção cooperativa para refletir sobre os obstáculos enfrentados pelos países sul-americanos.

Abstract The last decade has shown the global society, especially South American society, the great challenges that democracies will face in the 21st century. Among the various threats observed in cyberspace are the so-called disinformation campaigns and hybrid interference. As a result, this new digital means of information socialization has caused serious damage to the democratic pillars of states, as disinformation and false information have become a feature of political debate. Based on this, the article seeks to analyze how South American countries are building cooperation in cybersecurity and cyber defense between 2012 and 2020, and what the implications are for the protection of democracy and the rule of law. It is argued that, due to the transnational dynamics of the digital world and the wide reach of its actions and consequences, the search for a solution to these demands goes through a process of deepening state cooperation, in which the foreign policy strategies of states are fundamental for building an effective response to this type of threat to democracy at the international level. From this perspective, we understand the interdependence between States in this sphere and adopt a cooperative conception to reflect on the obstacles South American countries face.

ABSTRACT Introduction/framework/objectives: Amyotrophic Lateral Sclerosis is a disease that can progress in a debilitating manner and affect some individuals of working age, so it will be important that professionals working in Occupational Health and Safety have a reasonable set of knowledge on the subject, to be able to adjust work tasks as best as possible, as well as any protective measures, enhancing well-being and performance/productivity. Furthermore, knowing the work factors that increase it, it will be possible to slightly reduce the incidence of the pathology. The aim of this review was to summarize in Portuguese the most current and relevant articles published on the topic in international and national literature. Methodology: This is a Bibliographic Review, initiated through a search carried out in April 2023 in the databases “CINALH plus with full text, Medline with full text, Database of Abstracts of Reviews of Effects, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, Cochrane Methodology Register, Nursing and Allied Health Collection: comprehensive, MedicLatina and RCAAP”. Content: This pathology is a rapidly progressive neurodegenerative disease characterized by muscular atrophy/paralysis, generally beginning in adulthood with an average survival of two to three years. The first manifestations generally involve asthenia of the lower limbs, generally in the 5th or 6th decade of life. Focal paralysis intensifies and spreads, reaching the respiratory muscles and culminating in respiratory failure. However, the pathophysiology is not clearly understood. Some researchers consider that the only environmental fact that could have any influence could be smoking; others even claim that the influence of global environmental exposure itself is controversial. At this level, with greater or lesser consensus, pesticides, fertilizers, solvents, heavy metals, formaldehyde, diesel, physical exertion/hypoxia, trauma and contact with electricity stand out. Therefore, there are also some professional sectors that may present greater risk. Discussion and Conclusions: Even though the prevalence of this pathology is low, some of these individuals are part of the active population, at least at an initial stage. No concrete data was found regarding protective measures or other relevant attitudes for the Health and Safety team to guide in this context. Even so, the authors succinctly recorded some items in this sense, depending on their professional experience, especially for pathologies with some similarities and more prevalent. It would be interesting for professionals working in a hospital environment, in an institution where there is a support consultation for users with this pathology, to focus a little on the topic, portraying the national reality and publishing their research in a magazine in the area, to disseminate knowledge at national level, with international extrapolation, given the scarcity of bibliography.

RESUMO Introdução/enquadramento/objetivos: A Esclerose Lateral Amiotrófica é uma doença que poderá evoluir de forma debilitante e atingir alguns indivíduos em idade ativa, pelo que será relevante que os profissionais a exercer na Saúde e Segurança Ocupacionais tenham um conjunto razoável de conhecimentos sobre o tema, de forma a conseguirem ajustar o melhor possível as tarefas laborais, bem como eventuais medidas de proteção, potenciando o bem-estar e desempenho/produtividade. Para além disso, conhecendo os fatores laborais que a potenciam, poder-se-á diminuir um pouco a incidência da patologia. Pretendeu-se com esta revisão resumir em português o que de mais atual e relevante se publicou sobre o tema nas literaturas internacional e nacional. Metodologia: Trata-se de uma Revisão Bibliográfica, iniciada através de uma pesquisa realizada em abril de 2023 nas bases de dados “CINALH plus with full text, Medline with full text, Database of Abstracts of Reviews of Effects, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, Cochrane Methodology Register, Nursing and Allied Health Collection: comprehensive, MedicLatina e RCAAP”. Conteúdo: Esta patologia é uma doença neurodegenerativa rapidamente progressiva e caraterizada por atrofia/paralisia muscular, geralmente iniciada na idade adulta com sobrevida média de dois a três anos. As primeiras manifestações geralmente incidem na astenia dos membros inferiores, geralmente na 5ª ou 6ª décadas de vida. A paralisia intensifica-se e alastra-se, podendo atingir os músculos respiratórios e culminar em insuficiência respiratória. Contudo, a fisiopatologia não está esclarecida com clareza. Alguns investigadores consideram que o único fator ambiental que poderá ter alguma influência poderá ser o tabagismo; outros até afirmam que a influência da exposição ambiental global em si é controversa. Neste contexto, com maior ou menor consenso, destacam-se os pesticidas, fertilizantes, solventes, metais pesados, formaldeído, diesel, esforço físico/hipoxia, trauma e contato com a eletricidade. Desta forma, existem também alguns setores profissionais que poderão apresentar maior risco. Discussão e Conclusões: Ainda que a prevalência desta doença seja baixa, parte destes indivíduos estão inseridos na população ativa, pelo menos numa fase inicial. Não se encontraram dados concretos relativos a medidas de proteção ou outras atitudes relevantes para a equipa de Saúde e Segurança orientar neste contexto; ainda assim, os autores registaram de forma sucinta alguns itens nesse sentido, em função da sua experiência profissional, sobretudo para patologias com algumas semelhanças e mais prevalentes. Seria aliciante que profissionais a exercer em ambiente hospitalar, em instituição que exista uma consulta de apoio a utentes com esta patologia, se debruçassem um pouco sobre o tema, retratando a realidade nacional e publicando a sua investigação em revista da área, para difusão de conhecimentos a nível nacional, com extrapolação internacional, dada a escassez de bibliografia.

Tolstoy'sfiction is part of the cultural background of the South African intelligentsia. Moreover, generations of South Africans have been introduced to Tolstoy through screen adaptations of hisfiction, including Hollywood blockbusters and acclaimed TV series such as Anna Karenina (1935, 1948 and 2012) and War and Peace (1956 and 2016). Such exposure may well be the reason why, in the late 1990s, a survey among South African students of their perceptions of Russia showed that Tolstoy was the best-known Russian writer. During his lifetime, Tolstoy's work and personality were discussed extensively in Russia and abroad, including South Africa. He was one of the most influential and authoritative writers in the world and remained the best-known Russian author in South Africa. Tolstoy was the only writer of Imperial Russia who, for decades, received letters and guests from South Africa. His statements on the Anglo-Boer War of1899-1902 (also known as the South African War) attracted international attention which none of his Russian colleagues could match. Tolstoy wrote on South Africa, and his work was widely read there. Thanks to his erudition, ability to discern global trends, and interest in world culture and philosophy, Tolstoy had a profound understanding of political events in countries that he never visited and inspired leaders of liberation movements that he never met. His influence on South African realist literature can be traced throughout the twentieth century. This study of Tolstoy's and South Africans' views of each other focuses on Afrikaners, because in the last ten years of his life the Russian author often wrote and spoke about them, as is evident from his published works, correspondence and the archival material in the Tolstoy museums in Moscow and Yasnaya Polyana in Russia that were used for this paper. Furthermore, Afrikaner authors seem to have referred to Tolstoy's work remarkably often. By exploring these references, one can ascertain why Tolstoy's writing remained relevant to Afrikaners and other South Africans for more than a century. In the 1890s and 1900s, Tolstoy continued to develop his doctrine of not resisting evil with violence. He used information on the Anglo-Boer War to test his radical pacifist ideas. His protest against British imperialism in Africa echoed that of other world-famous humanist writers, such as Bjornstjerne Bjornson, Theodore Dreiser, Anatole France, Romain Rolland, Bernard Shaw, Bertha von Suttner and Mark Twain. But, unlike most of them, Tolstoy refused to support the Boers unconditionally. He sympathised with the defenders of the Boer republics, but as a principled opponent ofviolence he condemned those Christian people for engaging in armed struggle and killing, which he regarded as a mortal sin. During the transitional and guerrilla phases of the war, Tolstoy came to regard the continued Boer resistance to British invasion as a triumph of moral strength over immorality. He viewed the South African military conflict in a global context, as a typical war of a new era. Reflecting on the news from South Africa, he concluded that such wars were characterised by immoral goals and methods of warfare, and by non-participation in hostilities by those who directly benefitted from the hostilities (big entrepreneurs manipulating the government). Tolstoy argued that European governments were not interested in eradicating militarism, but nonviolent protest by ordinary people could well put an end to war. However, Tolstoy believed Russians, unlike participants in mass pro-Boer campaigns, were not to concern themselves with such protest because instead their main tasks were moral self-improvement and tackling injustice in their homeland. His concern with affairs in South Africa was limited to the Anglo-Boer War and the Indian civil rights campaign of the 1900s led by Gandhi, whose doctrine of satyagraha was partly based on Tolstoy's ethical teachings. Still, Tolstoy's influence on Afrikaner culture has been evident for over a century. Apartfrom direct contact, such as visits and letters to the Russian writer, Afrikaner cultural figures promoted his work, translated his fiction into Afrikaans and published their translations in almost every decade up to the 1990s. Along with other distinguished novelists of the late Imperial Russia, Tolstoy was viewed by Afrikaans authors as an exemplary realist writer who set standards that they aspired to but often regarded as unattainable. It only applied to his fiction, because Tolstoy's confessional writings and philosophical treatises did not seem to be recognised by Afrikaans authors, especially not after the Second World War. For these authors, Tolstoy was primarily a fiction writer. Tolstoy's work featured in South African literary debates with regard to resistance to abusive state authority and grappled with censorship. His fiction reminded South Africans of the humanist ideals that were meant to guide those who wanted to bring about positive change in an unjust, deeply divided society. Tolstoy's work stimulated introspection and reflection on literary mastery, the ethical standards of a writer and one's purpose in life.

Tolstoi was die enigste skrywer in Imperiale Rusland wat oor dekades briewe en gaste uit Suid-Afrika ontvang het. Sy stellings oor die Anglo-Boereoorlog van 1899-1902 het internasionaal aandag getrek op 'n wyse wat geeneen van sy Russiese kollegas kon ewenaar nie. Tolstoi het oor Suid-Afrika geskryf, waar sy werk wyd gelees is. Tolstoi se invloed op Suid-Afrikaanse realistiese¹ letterkunde is deur die hele twintigste eeu merkbaar. Hierdie studie van Tolstoi en Suid-Afrikaanse skrywers se sieninge van mekaar fokus op Afrikaners, want Tolstoi het in die laaste tien jaar van sy lewe dikwels oor hulle geskryf en gepraat. Afgesien van regstreekse kontak, soos besoeke en briewe aan die Russiese skrywer, het Afrikaner-kultuurfigure sy werk bevorder, sy fiksie in Afrikaans vertaal en hul vertalings in feitlik elke dekade tot die 1990's gepubliseer. Tolstoi, soos ook ander vooraanstaande romansiers in laat Imperiale Rusland, is deur Afrikaanse skrywers beskou as 'n toonbeeld van 'n realistiese skrywer wat standaarde gestel het waarna hulle gestreef het maar wat hulle dikwels ook as onhaalbaar beskou het. Tolstoi se werk het in Suid-Afrikaanse literêre debatte oor weerstand teen onregmatige staatsgesag en sensuur gefigureer. Sy fiksie het Suid-Afrikaners herinner aan die humanistiese ideale wat as rigsnoere moes dien vir diegene wat positiewe verandering in 'n onregverdige en diep verdeelde samelewing teweeg wou bring. Tolstoi se werk het introspeksie en nadenke oor literêre uitnemendheid, die etiese standaarde van 'n skrywer en 'n mens se lewensdoel gestimuleer.

Acute mesenteric ischemia (AMI) is a rare medical-surgical emergency that must be treated early due to its high morbidity and mortality. It corresponds to a sudden interruption of the blood supply to a segment of the intestine, producing ischemia, cell damage, intestinal necrosis and eventually death if it is not treated. The main etiology of this condition is embolic-type arterial occlusion, followed by thrombotic, nonocclusive, and venous thrombotic. It is an infrequent pathology with a low incidence of 12 per 100,000 inhabitants in international series. During the information collection, no data was found on the Chilean population since before 1983. Its main symptom is colicky abdominal pain with a sudden onset, vomiting and diarrhea that begins after the pain. On physical examination, signs of shock and abdominal distention may be noted. Hemodynamically unstable patients should be urgently taken to exploratory laparotomy as soon as the condition is suspected, and in stable patients, an angio-CT should be requested to confirm the diagnosis and plan treatment. There are two methods to treat this pathology, open surgery and endovascular or minimally invasive surgery. The form of therapy depends on the preoperative or intraoperative findings and the type of etiology. Finally, with the advancement of these new methods, the mortality rate has decreased in the last decade.

Resumen La isquemia mesentérica aguda (IMA) es una emergencia médico-quirúrgica poco frecuente con alta morbimortalidad. Corresponde a una interrupción brusca del aporte sanguíneo a un segmento del intestino, produciendo isquemia, daño celular, necrosis intestinal y eventualmente la muerte. La principal etiología de este cuadro es la oclusión arterial de tipo embólica, seguida por la trombótica, no oclusiva y trombótica venosa. Es una patología infrecuente con una incidencia baja, de 12 por 100.000 habitantes en series internacionales. Su principal síntoma es el dolor abdominal tipo cólico de comienzo brusco, vómitos y diarrea, esta última sucediendo posteriormente. En el examen físico se pueden constatar signos de shock y distensión abdominal. Ante la sospecha, los pacientes hemodinámicamente inestables deben ser llevados urgentemente a laparotomía exploradora, y en aquellos estables, se debe solicitar un Angio-TC para confirmar el diagnóstico y planificar el tratamiento. Existen dos métodos para tratar esta patología: la cirugía abierta y la cirugía endovascular o mínimamente invasiva. Finalmente, con el avance de estos nuevos métodos, la tasa de mortalidad ha disminuido, significativamente, en la última década.

Abstract The development model of Latin American countries turns them into suppliers of raw materials for the international market, whose growing requirements promote the expansion of extractive activities on the rural territories in which peasant and indigenous communities settle. This integration into the world market generates socio-environmental conflicts. The resistance and opposition of the communities to the expansion of extractivism over their area of residence activates mechanisms of criminalization and repression by State security institutions and de facto powers. The present work carries out a historical recovery of the mechanisms of stigmatization, criminalization, and state repression in response to the organization and struggle for land by residents of northern Paraguay who were part of the first land occupation after the fall of the dictatorship. This historical episode clarifies the criminalizing and repressive process installed since the second half of the first decade of the 21st century.

Resumen El modelo de desarrollo de los países latinoamericanos los convierte en proveedores de materias primas para el mercado internacional, cuyos requerimientos crecientes promueven la expansión de actividades extractivas sobre los territorios rurales en los que se asientan comunidades campesinas e indígenas. Esta integración al mercado mundial genera conflictos socioambientales. La resistencia y la oposición de las comunidades a la expansión del extractivismo sobre su área de residencia activa mecanismos de criminalización y represión por parte de instituciones de seguridad del Estado y poderes fácticos. El presente trabajo realiza una recuperación histórica de los mecanismos de estigmatización, criminalización y represión estatal en respuesta a la organización y la lucha por la tierra por parte pobladores y pobladoras del norte paraguayo que fueron parte de la primera ocupación de tierras luego de la caída de la dictadura. Ese episodio histórico esclarece el proceso criminalizador y represor instalado desde la segunda mitad de la primera década del siglo XXI.

Abstract The Anais Brasileiros de Dermatologia, published since 1925, is the most influential dermatological journal in Latin America, indexed in the main international bibliographic databases, and occupies the 50th position among the 70 dermatological journals indexed in the Journal of Citations Reports, in 2022. In this article, the authors present a critical analysis of its trajectory in the last decade and compare its main bibliometric indices with Brazilian medical and international dermatological journals. The journal showed consistent growth in different bibliometric indices, which indicates a successful editorial policy and greater visibility in the international scientific community, attracting foreign authors. The increases in citations received (4.1 ×) and in the Article Influence Score (2.9×) were more prominent than those of the main Brazilian medical and international dermatological journals. The success of Anais Brasileiros de Dermatologia in the international scientific scenario depends on an assertive editorial policy, on promptly publication of high-quality articles, and on institutional stimulus to encourage clinical research in dermatology. 1925 America databases th 7 Reports 2022 article community 4.1 41 4 1 (4. × 2.9× 29 2 9 (2.9× highquality high quality articles dermatology 192 202 4. (4 2.9 (2.9 19 20 ( 2. (2. (2

Abstract The crisis caused by the COVID-19 pandemic, the growing financing needs, and the consequent deterioration of public finances in many countries have created a propitious scenario for the return of the International Monetary Fund (IMF) to Latin America after almost a decade and a half of their estrangement. This paper aims at analyzing the relationship between the organization and the region in the context of the coronavirus. We seek to understand to what extent their renewed relations will mirror the IMF's “old-fashioned” preferences that have characterized its interventions during the last two decades of the 20th century and the beginning of the 21st century. For this purpose, we first examine the Fund's official position, reflected in its flagship publications. We affirm that the institution, in its discourse, is increasingly permissive with the use of fiscal stimulus and the State's leading role in crisis resolution. Second, we confront the IMF's rhetoric with its practices, reflected in conditionality and policy recommendations contained in specific agreements signed with Latin American countries in the context of the current crisis. We conclude that the orthodox approach persists in the IMF's practices, but is accompanied by growing adaptive changes.

Resumen La crisis provocada por la pandemia de COVID-19, las crecientes necesidades de financiamiento y el consiguiente deterioro de las finanzas públicas de muchos países han creado un escenario propicio para el regreso del Fondo Monetario Internacional (FMI) a América Latina después de casi una década y media de distanciamiento. El artículo tiene como objetivo analizar las relaciones entre la organización y la región en el contexto del coronavirus. Buscamos comprender hasta qué punto las renovadas relaciones serán el espejo de las “viejas” preferencias del FMI que han caracterizado sus intervenciones en las últimas dos décadas del siglo XX y principios del siglo XXI. Primero, examinamos la postura oficial del Fondo reflejada en sus publicaciones emblemáticas. Afirmamos que la institución, en su discurso, es cada vez más permisiva con el uso del estímulo fiscal y frente al protagonismo del Estado en la resolución de crisis. Posteriormente, confrontamos la retórica del FMI con sus acciones concretas, reflejadas en la condicionalidad y las recomendaciones de política contenidas en los acuerdos firmados con los países latinoamericanos en el contexto de la crisis sanitaria. Concluimos que el enfoque ortodoxo persiste en las prácticas del FMI, pero está acompañado por crecientes cambios adaptativos.

ABSTRACT Although lung cancer (LC) is one of the most common and lethal tumors, only 15% of patients are diagnosed at an early stage. Smoking is still responsible for more than 85% of cases. Lung cancer screening (LCS) with low-dose CT (LDCT) reduces LC-related mortality by 20%, and that reduction reaches 38% when LCS by LDCT is combined with smoking cessation. In the last decade, a number of countries have adopted population-based LCS as a public health recommendation. Albeit still incipient, discussion on this topic in Brazil is becoming increasingly broad and necessary. With the aim of increasing knowledge and stimulating debate on LCS, the Brazilian Society of Thoracic Surgery, the Brazilian Thoracic Association, and the Brazilian College of Radiology and Diagnostic Imaging convened a panel of experts to prepare recommendations for LCS in Brazil. The recommendations presented here were based on a narrative review of the literature, with an emphasis on large population-based studies, systematic reviews, and the recommendations of international guidelines, and were developed after extensive discussion by the panel of experts. The following topics were reviewed: reasons for screening; general considerations about smoking; epidemiology of LC; eligibility criteria; incidental findings; granulomatous lesions; probabilistic models; minimum requirements for LDCT; volumetric acquisition; risks of screening; minimum structure and role of the multidisciplinary team; practice according to the Lung CT Screening Reporting and Data System; costs versus benefits of screening; and future perspectives for LCS. LC (LC tumors 15 stage 85 cases (LCS lowdose low dose (LDCT LCrelated related 20 20% 38 cessation decade populationbased population recommendation incipient necessary Surgery Association literature studies reviews guidelines reviewed criteria findings lesions models acquisition team System 1 8 2 3

RESUMO O câncer de pulmão (CP) é uma das neoplasias mais comuns e letais no Brasil, e apenas 15% dos pacientes são diagnosticados nos estágios iniciais. O tabagismo persiste como o responsável por mais de 85% de todos os casos. O rastreamento do CP (RCP) por meio da TC de baixa dosagem de radiação (TCBD) reduz a mortalidade do CP em 20%, e, quando combinado com a cessação do tabagismo, essa redução chega a 38%. Na última década, diversos países adotaram o RCP como recomendação de saúde populacional. No Brasil, embora ainda incipiente, a discussão sobre o tema é cada vez mais ampla e necessária. Com o intuito de aumentar o conhecimento e estimular o debate sobre o RCP, a Sociedade Brasileira de Cirurgia Torácica, a Sociedade Brasileira de Pneumologia e Tisiologia e o Colégio Brasileiro de Radiologia e Diagnóstico por Imagem constituíram um painel de especialistas para elaborar as recomendações para o RCP. As recomendações aqui apresentadas foram baseadas em revisão narrativa da literatura, com ênfase em grandes estudos populacionais, em revisões sistemáticas e em recomendações de diretrizes internacionais, sendo construídas após ampla discussão pelo grupo de especialistas. Os temas revisados foram os seguintes: porque rastrear, considerações gerais sobre tabagismo, epidemiologia do CP, critérios de elegibilidade, achados incidentais, lesões granulomatosas, modelos probabilísticos, requisitos mínimos da TCBD, aquisições volumétricas, riscos do rastreamento, estrutura mínima e papel da equipe multidisciplinar, conduta segundo o Lung CT Screening Reporting and Data System (Lung-RADS), custos vs. benefícios e perspectivas do rastreamento. (CP Brasil 15 iniciais 85 casos (RCP TCBD (TCBD 20 20% 38 38% década populacional incipiente necessária Torácica literatura populacionais internacionais seguintes rastrear elegibilidade incidentais granulomatosas probabilísticos volumétricas multidisciplinar LungRADS, LungRADS RADS , (Lung-RADS) vs 1 8 2 3 (Lung-RADS

Abstract Over the past twenty years, in different parts of the world, there has been an increase in environmental conflicts related to mining activities. In order to understand how agents in the extractive sector have described these conflicts and the way in which they have acted in response to them, this article analyzes two sets of publications produced during the last decade. Risk and trend reports for the extractive sector prepared through consultancies by Ernst & Young, PricewaterhouseCoopers, Deloitte and KPMG and three community relations manuals issued by the Brazilian Mining Institute, the National Confederation of Industry and the International Mining and Metals Council. We identified that the production and circulation of these materials are part of a set of authoritarian practices by extractive corporations set within at least three dimensions: i) an understanding that organized social actors who act in the defense of territories are risks that need to be managed; ii) the dissemination of “dialogue” and “social participation” techniques used to identify and classify social actors and iii) promoting the idea that the destiny of the territory is ineluctably linked to the corporation. years world activities them decade Young PricewaterhouseCoopers Institute Council dimensions i managed ii dialogue “dialogue participation iii corporation

Resumo Nos últimos vinte anos, observou-se um aumento dos conflitos ambientais relacionados às atividades de mineração em diversas partes do mundo. A fim de compreender como os agentes do setor extrativo descrevem estes conflitos e de que forma têm atuado para respondê-los, este artigo analisará dois conjuntos de publicações produzidos na última década. Os relatórios de riscos e tendências do setor extrativo elaborados pelas consultorias Ernst & Young, PricewaterhouseCoopers, Deloitte e KPMG e três manuais de relacionamento com comunidades do Instituto Brasileiro de Mineração, da Confederação Nacional da Indústria e do Conselho Internacional de Mineração e Metais. Identificamos que a produção e a circulação destes materiais integram o conjunto de práticas autoritárias das corporações extrativas em pelo menos três dimensões: i) a compreensão de que atores sociais organizados que atuam na defesa dos territórios são riscos a serem gerenciados; ii) à difusão de técnicas de “diálogo” e “participação social” utilizadas para a identificação e classificação dos atores sociais e iii) a promoção da ideia de que o destino do território está inelutavelmente ligado à corporação. anos observouse observou se mundo respondêlos, respondêlos respondê los, los respondê-los década Young PricewaterhouseCoopers Metais dimensões i gerenciados ii diálogo “diálogo participação social iii corporação