Alfred Schaeffer (1879-1957) was a German chemist who arrived in Minas Gerais in 1911 hired by the state government to organize the state health service in its newly established capital. He directed the Laboratory of Chemical Analysis of the State, and his analytical methods in dairy and mineral waters became a reference in Brazil. He also became professor of Chemistry at the new Faculty of Medicine of Belo Horizonte and founded the Chemistry Institute of the Engineering School in that city, influencing several students who became important names in Brazilian science. In addition, he was responsible for the assembly and technical coordination of pioneering industries in the dairy and wood distillation sector in the city of Santos Dumont. Later he assumed the post of technical director of Merck, also in Minas Gerais. Moving to Rio de Janeiro, he assumed a chair at the Technical School, working in teaching and research, and remained active even after retiring, publishing in important scientific journals. 18791957 1879 1957 (1879-1957 191 capital State Brazil science addition Dumont Merck Janeiro research retiring journals 1879195 187 195 (1879-195 19 187919 18 (1879-19 1 18791 (1879-1 (1879- (1879 (187 (18 (1 (

To discover new bisamide compounds with insecticidal and fungicidal activities, 19 novel cyproflanilide derivatives containing 1,2,4-oxadiazole group were designed and synthesized according to the principle of biologically active factor splicing. Preliminary biological assay data indicated that the majority of target compounds demonstrated significant insecticidal activity against Lepidopteran pests. Meanwhile, compounds 5p and 5q showed 97.22 and 100% lethality against Tetranychus cinnabarinus at 400 mg L-1, which were better than cyproflanilide (41.11% at 400 mg L-1). In addition, it is exciting that we have achieved our initial goals as some of the target compounds exhibited both insecticidal and fungicidal activities. For instance, compounds 5b and 5c showed 59.26 and 74.07% fungicidal activities against Cucumber downy mildew at 400 mg L-1, as well as 100% insecticidal activity against Plutella xylostella and armyworm at 100 mg L-1. Compound 5h showed 100% insecticidal activity against armyworm at 10 mg L-1, and also displayed 66.67% fungicidal activity against Cucumber downy mildew at 400 mg L-1. The inhibition rate of compounds 5l and 5s against Cucumber downy mildew reached 88.89 and 96.30% at 400 mg L-1. This work showed the effectively fungicidal application of 1,2,4-oxadiazole group in bisamide compounds and provides insights for optimal structural design. 1 1,2,4oxadiazole 124oxadiazole oxadiazole 1,2,4 2 4 splicing pests Meanwhile p q 9722 97 22 97.2 40 L1, L1 L 1, L-1 41.11% 4111 41 11 (41.11 L1. . L-1) addition instance b c 5926 59 26 59.2 7407 74 07 74.07 1. h 6667 66 67 66.67 l s 8889 88 89 88.8 9630 96 30 96.30 design 4oxadiazole 124 1,2, 972 9 97. L- 41.11 411 (41.1 592 5 59. 740 7 0 74.0 666 6 66.6 888 8 88. 963 3 96.3 12 1,2 41.1 (41. 74. 66. 96. 41. (41 (4 (

Die prosesse wat gebruik word om onroerende eiendom van verkoper na koper in Suid-Afrika oor te dra, is verouderd en nie outomaties nie. Dokumente in papierformaat verhoog die risiko vir bedrog en wanvoorstellings. Hierdie artikel oorweeg die implementering van 'n wolkgebaseerde, gesentraliseerde databasis met eiendomsaanvoerkettingvennote, om deursigtigheid, omkeertyd en sekuriteit te verbeter, terwyl die risiko en koste geminimaliseer word. Die digitalisering van eiendomsprosesse sou lei tot die dematerialisering van die titelbewys, en nie bloot outomatisering van die papiergebaseerde stelsel nie. Die kwalitatiewe navorsing was verkennend, en halfgestruktureerde onderhoude is gevoer met rolspelers betrokke by eiendomsoordragte in Suid-Afrika. Dit het die Suid-Afrikaanse Reserwebank, die Departement van Landbou, Grondhervorming en Landelike Ontwikkeling, die Prokureursorde van Suid-Afrika, verbandopstellers, Die Bankvereniging, die Departement van Binnelandse Sake, die registrateur van die aktekantoor, die landmeter-generaal, munisipaliteite, sagtewaremaatskappye, die Nasionale Tesourie, Suid-Afrika se Sentrale Sekuriteitebewaarplek, sowel as die Tshwane Munisipaliteit se Raad, ingesluit.

The processes used to transfer immovable property from a seller to a buyer in South Africa are outdated and not digitised. Paper-based documents increase the risk of fraud and misrepresentation. This study considered the implementation of a cloud-based centralised database for property supply chain partners to enhance transparency, turnaround times, and security while minimising risks and costs. Digitalised property processes would result in title deeds' dematerialisation and not merely the automation of the paper-based system. This qualitative study was exploratory, and semi-structured interviews were conducted with role-players involved with property transfers in South Africa. These included the South African Reserve Bank, the Department of Agriculture, Land Reform and Rural Development, the Law Society of South Africa, mortgage originators, The Banking Association, the Department of Home Affairs, the Registrar of each Deeds Office, the Surveyor General's office, municipalities, software companies, National Treasury, South Africa's Central Securities Depository (Strate Ltd), and the Tshwane Mettropolitan Municipal Council.

Abstract Introduction: Spills of flammable liquids can lead to serious accidents, mainly in industrial plants and on roads. To prevent the spread of spills, various forms of collection are used, such as absorption with porous solids. Agroindustrial waste can be used as sorbent materials for flammable liquids. Objective: To determine the sorption capacity of the residual empty-fruit bunch of oil-palm (Elaeis guineensis) and the macaw palm (Acrocomia sp.) nutshell for four organic flammable liquids. Methods: The residual biomasses of E. guineensis and Acrocomia sp. were assessed as sorbents for spilled fuels (diesel, jet fuel, commercial kerosene, and gasoline). Volumetric measurement of liquid-fuel absorption at 24 ºC was taken during a week. Desorption was measured at 50 ºC as the drying kinetics, by using moisture scales. Results: The sorption capacity of the Acrocomia sp. material was not satisfactory, compared to the E. guineensis residual material, due to differences in the residual architecture of the organic material. This last can absorb 2.4 ± 0.2 cm3 g-1 at 24 ºC, during a one-week period. Diatomite absorbs greater quantities of the organic liquids but, the fluids diffusion at 50 ºC is 0.26 ± 0.09 times more slowly in the mineral matrix, because of the greater pore tortuosity in this mineral matrix. Conclusions: The oil-palm empty fruit bunch of E. guineensis, showed lesser but adequate performance than the sorbing behavior for fire hazard mitigation of diatomite. The nutshell of macaw palm (Acrocomia sp.) did not prove to be useful for this recovery operation.

Resumen Introducción: Los vertidos de líquidos inflamables pueden producir accidentes graves, principalmente en plantas industriales y en carretera. Para prevenir la dispersión de derrames, se utilizan diversas formas de recolecta, como la absorción con sólidos porosos. Residuos agroindustriales pueden ser aprovechados como materiales sorbentes de líquidos inflamables. Objetivo: Determinar la capacidad de absorción de las biomasas residuales del pedúnculo de la palma aceitera (Elaeis guineensis) y del endocarpio del fruto de coyol (Acrocomia sp.) para cuatro líquidos orgánicos inflamables. Métodos: Las biomasas residuales de E. guineensis y de Acrocomia sp. se evaluaron como sorbentes para combustibles derramados (diésel, queroseno de aviación, queroseno comercial y gasolina). Se midió la cantidad de líquido absorbida por las biomasas a 24 ºC durante una semana, y su cinética de desorción a 50 ºC, usando balanzas de secado. Resultados: La propiedad sorbente del material de Acrocomia sp. no fue satisfactoria, comparada con el pedúnculo de E. guineensis, debido a diferencias en arquitectura residual del material orgánico. Esta última biomasa muestra una capacidad de absorción para los combustibles de 2.4 ± 0.2 cm3 g-1 a 24 ºC. La diatomita absorbe mayor cantidad de los combustibles estudiados, pero la difusión de estos fluidos a 50 ºC por la matriz mineral es solo 0.26 ± 0.09 veces lo observado para el material de E. guineensis, como resultado del mayor grado de tortuosidad de los poros de la diatomita. Conclusiones: El pedúnculo de palma aceitera (E. guineensis) mostró un adecuado potencial desempeño para la aplicación pasiva en la mitigación de los riesgos de incendio, con respecto a la diatomita. El endocarpio del fruto de Acrocomia sp. no resultó útil para esta operación de recuperación.

Abstract The “International Group for Lean Construction” aims to adopt a new management philosophy for the Architecture, Engineering, and Construction (AEC) industry. Learning this philosophy can be supported by using active methodologies, especially serious games. This work aimed to analyse the evolution of using serious games as a teaching technique based on problem classes, in the context of the Lean Construction community. A literature review and an analysis of an empirical experience were carried out in an architecture and urbanism undergraduate course. The results demonstrate the evolution of the use of these techniques, as well as their implications for the education and training of AEC professionals. International Architecture Engineering (AEC industry methodologies classes community course techniques professionals

Resumo O “International Group for Lean Construction” busca adaptar à indústria de Arquitetura, Engenharia e Construção (AEC) uma nova filosofia gerencial. O aprendizado dessa filosofia pode ser apoiado pela utilização de metodologias ativas, especialmente dos jogos didáticos (do inglês “serious games”). Este trabalho teve como objetivo analisar a evolução da aplicação de jogos didáticos como técnica de aprendizagem baseada em classes de problemas, no contexto da comunidade da Construção Enxuta.Foi realizada uma revisão sistemática de literatura e a análise de uma experiência empírica, em uma disciplina de graduação de arquitetura e urbanismo. Os resultados demonstram a evolução do uso dessas técnicas, bem como suas implicações para a formação e treinamento de profissionais da AEC. International Construction Arquitetura AEC (AEC gerencial ativas serious games. games . games”) problemas EnxutaFoi Enxuta Foi empírica urbanismo técnicas games”

Abstract Only within the last decade, the works of Uruguay an Engineer Eladio Dieste (1917-2000) have been gaining international academic dissemination, one of whose main contributions in the realm of formal-structural conception within architecture and civil engineering reside in the iterative development of the structural typology of the gaussian vault shells in reinforced brickwork. However, there is not an established definition for this typology’s architectural geometry. Also, there is hardly any evidence of how such shells were designed. Therefore, the main objective, of this paper is to demonstrate the underlying geometric relationships in the discontinuous gaussian vault shells designed and built by Eladio Dieste in reinforced brickwork, the dominant typological variation within the object of study. This analysis was carried out by means of the parametric modeling and the polynomial regression of selected case studies from the primary sources, since such computational tools allow for the proper geometrical management of formally complex geometries. The expected contributions of this study reside in the deepening of the understanding of the relationship between the design process and the geometry of the object of study, as well as the understanding of the geometrical conformation of the structural typology conceived by Eladio Dieste. decade 19172000 1917 2000 (1917-2000 dissemination formalstructural formal brickwork However typologys s Also Therefore objective sources geometries 1917200 191 200 (1917-200 191720 19 20 (1917-20 19172 1 2 (1917-2 (1917- (1917 (191 (19 (1 (

Resumo Apenas na última década, a obra do engenheiro Uruguaio Eladio Dieste (1917-2000) vem ganhando disseminação acadêmica internacional, sendo que uma de suas principais contribuições para a concepção formal-estrutural na arquitetura e engenharia civil foi o desenvolvimento iterativo da tipologia estrutural das abóbadas gaussianas, cascas de dupla-curvatura estruturadas em cerâmica armada. Entretanto, não há registros de uma definição estabelecida para a geometria arquitetônica destas tipologias estruturais. Tampouco existem evidências concretas acerca da concepção e desenvolvimento projetual destas estruturas. Por conseguinte, o objetivo deste artigo é evidenciar as relações geométricas subjacentes nas abóbadas guassianas descontínuas projetadas e construídas por Eladio Dieste em cerâmica armada, a variação dominante desta tipologia estrutural. Esta análise foi conduzida através da modelagem paramétrica e da regressão polinomial de estudos de caso selecionados a partir de fontes primárias originais, justamente por estas ferramentas computacionais permitirem o correto manejo de geometrias tidas como formalmente complexas. A contribuição esperada para esta pesquisa reside em aprofundar o entendimento entre a relação do processo de projeto e a geometria resultante no objeto de estudo, assim como o entendimento da conformação geométrica desta tipologia estrutural desenvolvida por Eladio Dieste. década 19172000 1917 2000 (1917-2000 internacional formalestrutural formal gaussianas duplacurvatura dupla curvatura armada Entretanto estruturais estruturas conseguinte originais complexas estudo 1917200 191 200 (1917-200 191720 19 20 (1917-20 19172 1 2 (1917-2 (1917- (1917 (191 (19 (1 (

Resumen (Objetivo) La enseñanza de la cuantificación suele enfocarse en fórmulas para cuantificar la medida de magnitudes geométricas, ignorando sus usos en otras disciplinas. Esto hace indispensable formular marcos de referencia que le permitan a dicha enseñanza atender las justificaciones funcionales demandadas por otros dominios de conocimiento. Por tal razón, y enmarcada en la socioepistemología, el objetivo de esta investigación fue formular una epistemología de usos de la cuantificación. (Metodología) La metodología fue cualitativa y estuvo conformada por un corpus teórico-metodológico que articuló constructos de la categoría de modelación con datos empíricos. Esta formulación se llevó a cabo en dos fases. En la primera se enunció, de manera hipotética, una epistemología con base en un análisis a la resignificación de usos de la cuantificación construida en dos situaciones específicas de medición: una propia de una comunidad interdisciplinar y otra propia de la obra matemática titulada Intégrale, Longueur, Aire. La segunda fase analizó la emergencia de una resignificación de usos de la cuantificación en estudiantes de ingeniería durante el desarrollo de una situación escolar diseñada con base en la epistemología hipotética. (Resultados) Esta emergencia permitió validar empíricamente esta epistemología y expresar una transversalidad de usos de la cuantificación en situaciones específicas de medición, conformadas de significaciones, procedimientos e instrumentos que en conjunto derivan argumentaciones de cuantificación. (Conclusiones) Esta epistemología de usos permite plasmar a la situación de medición como un referente educativo para establecer el uso, la resignificación y la transversalidad de la cuantificación.

Resumo (Objetivo) O ensino da quantificação geralmente se concentra em fórmulas para quantificar a medição de magnitude geométricas, ignorando seus usos em outras disciplinas. Isso torna essencial a formulação de estruturas de referência que permitam que esse ensino atenda às justificativas funcionais xigidas por outros domínios do conhecimento. Por esse motivo, e dentro da estrutura da epistemologia social, o objetivo desta pesquisa foi formular uma epistemologia dos usos da quantificação. (Metodologia) A metodologia foi qualitativa e consistiu em um corpus teórico-metodológico que rticulou construções da categoria de modelagem com dados empíricos. Essa formulação foi realizada em duas fases. O primeiro enunciou hipoteticamente uma epistemologia baseada em uma análise da ressignificação dos usos da quantificação construída em duas situações específicas de medição: uma specífica de uma comunidade interdisciplinar e a outra do trabalho matemático intitulado Intégrale, Longueur, Aire. A segunda fase analisou o surgimento de uma ressignificação dos usos da quantificação em estudantes de engenharia durante o desenvolvimento de uma situação escolar projetada com base na epistemologia hipotética. (Resultados) Esse surgimento permitiu validar empiricamente essa epistemologia e expressar uma transversalidade de usos da quantificação em situações específicas de medição, composta de significados, procedimentos e instrumentos que, juntos, derivam argumentos de quantificação. (Conclusões) Essa epistemologia de usos permite que a situação de medição seja moldada como uma referência educacional para estabelecer o uso, a ressignificação e a transversalidade da quantificação.

Abstract (Objective) The teaching of quantification tends to focus on formulas for quantifying the measurement of geometric magnitudes, ignoring their uses in other disciplines. This makes it essential to formulate reference frameworks that allow such teaching to meet the functional justifications demanded by other domains of knowledge. For this reason, and within the framework of socioepistemology, the aim of this research was to formulate an epistemology of the uses of quantification. (Methodology) The methodology was qualitative and consisted of a theoretical-methodological corpus that articulated onstructs of a modelling category with empirical data. This formulation was carried out in two phases. In the first one, an epistemology was hypothetically formulated based on an analysis of resignification of the uses of quantification constructed in two specific measurement situations: one specific to an interdisciplinary community, and the other to the mathematical work entitled Intégrale, Longueur, Aire. The second phase analyzed the emergence of a resignification of the uses of quantification by engineering students during the development of a school situation designed on the basis of hypothetical epistemology. (Results) This emergence made it possible to empirically validate this epistemology and to express a transversality of uses of quantification in specific measurement situations, made up of meanings, procedures and instruments that together can be u sed to derive quantification arguments. (Conclusions) This epistemology of uses makes it possible to capture the measurement situation as an educational reference to establish the use, resignification, and transversality of quantification.

Resumen (Objetivo) El objetivo de este artículo es presentar los resultados de la implementación de un diseño instruccional de enseñanza de la derivada para estudiantes universitarios de la carrera de Ingeniería Comercial en Chile. (Metodología) Las personas participantes del estudio son noventa estudiantes de la asignatura de Cálculo Aplicado a los Negocios de una universidad chilena. El diseño metodológico, basado en las herramientas del Enfoque Ontosemiótico del Conocimiento e Instrucción Matemáticos, considera diversas configuraciones epistémicas en las situaciones-problemas sobre tangentes, el cálculo de derivadas a partir de reglas de derivación, aplicaciones de la derivada para el cálculo de máximos y mínimos y análisis de gráficas de funciones. Además, integra las TIC en las diversas tareas. (Resultados) Los resultados indican que la propuesta instruccional de enseñanza de la derivada supera algunas de las dificultades de aprendizaje de los y las estudiantes, evidenciadas en diversas investigaciones. En particular, las dificultades del estudiantado de Ingeniería Comercial en torno a la concepción euclidiana de la recta tangente; la interpretación de la función “derivada” y su representación geométrica, la optimización de funciones económicas y la aplicación de la derivada a funciones marginales. (Conclusiones) Se concluye que el proceso de enseñanza y aprendizaje es eficaz, en el sentido de que se consigue el aprendizaje del alumnado de una carrera de ingeniería específica mediante la incorporación, en la instrucción, de diferentes configuraciones epistémicas de la derivada interconectadas, sus diferentes campos de problemas y las aplicaciones contextuales en su profesión, junto al uso de recursos TIC.

Resumo (Objetivo) O objetivo deste artigo é apresentar os resultados da implementação de um desenho instrucional para o ensino da derivada para alunos de graduação em Engenharia de Negócios no Chile. (Metodologia) Os participantes do estudo são noventa alunos da disciplina de Cálculo Empresarial Aplicado de uma universidade chilena. O desenho metodológico, baseado nas ferramentas da Abordagem Ontossemiótica do Conhecimento e Instrução Matemática, considera diversas configurações epistêmicas nas situações-problemas sobre tangentes, cálculo de derivadas a partir de regras de derivadas, aplicações da derivada para o cálculo de máximos e mínimos e análise de gráficos de funções. Além disso, integra as TIC nas diversas tarefas. (Resultados) Os resultados indicam que a proposta instrucional para o ensino da derivada supera algumas das dificuldades de aprendizagem dos alunos, conforme evidenciado em várias pesquisa. Em particular, as dificuldades dos alunos de Engenharia de Negócios sobre a concepção euclidiana da reta tangente; sobre a interpretação da função “derivada” e sua representação geométrica, sobre a otimização de funções econômicas e a aplicação da derivada a funções marginais. (Conclusões) Conclui-se que o processo de ensino e aprendizagem é eficaz, no sentido de que a aprendizagem dos alunos em um curso de engenharia específico, é alcançada por meio da incorporação, na instrução, de diferentes configurações epistêmicas da derivada interconectadas, dos diferentes campos de problemas e das aplicações contextuais em sua profissão, juntamente ao uso de recursos de TIC.

Abstract (Objective) The objective of this article is to present the results of the implementation of an instructional design for the teaching of the derivative for undergraduate students of Business Engineering in Chile. (Methodology) The participants in the study were ninety students of Applied Business Calculus at a Chilean university. The methodological design, based on the tools of the Ontosemiotic Approach to Mathematical Cognition and Instruction, consider various epistemic configurations in situations-problems concerning tangents, the calculation of derivatives from the rules for derivation, applications of the derivative for the calculation of maxima and minima, and analysis of graphs of functions. In addition, it integrates ICT into various activities. (Results) The results indicate that the instructional proposal for teaching the derivative overcomes some of students’ learning difficulties, as shown in various research studies. In particular, these include the difficulties that Business Engineering students have with the Euclidean conception of the tangent line, the interpretation of the derivative function and its geometric representation, the optimization of economic functions, and the application of the derivative to marginal functions. (Conclusions) It is concluded that the teaching and learning process is effective, in the sense that student learning for a specific engineering career is achieved by instruction that incorporates different interconnected epistemic configurations of the derivative, its different fields of problems, and contextual applications in their profession, together with the use of ICT resources.

Abstract Incorporating BIM in the education of professionals has become a demand and a topic of high importance for higher education. Several proposals for a curricular implementation of BIM exist. However, in most cases, they are specific to a single university or domain, do not consider academic policies or simplify practice by segmenting knowledge. This work proposes a protocol for the curricular implementation of BIM similar to the industry, considering aspects of process, technology, and policies aligned with the educational institution's mission and with existing competencies. Action research was the used method. Three actions were conducted: (1) proposition, (2) systematization and (3) application. The actions were executed in cycles incrementally, resulting in (1) guidelines, (2) supporting tools and (3) implementation plans. Two Brazilian universities participated in pilot studies of Project Construa Brasil. The pilot studies inspired a network of BIM cells that have synchronously applied curricular BIM implementation guidelines on a large scale. The guidelines proved to be generic and comprehensive, guiding the transformation with an empirical basis for the academics' decision-making. Leadership of a BIM specialist was confirmed as an essential factor of success. It is observed that even with a timid introduction of BIM competence in a limited scope of engineering solutions, the impact on the BIM maturity curriculum is significant. exist However cases domain knowledge industry process technology institutions institution s competencies method conducted 1 (1 proposition 2 (2 3 (3 application incrementally plans Brasil scale comprehensive academics decisionmaking. decisionmaking decision making. making decision-making success solutions significant (

Resumo Incorporar o BIM na formação de profissionais tornou-se uma demanda e um tema de grande importância para o ensino superior. Existem várias propostas de implementação curricular do BIM. No entanto, na maioria dos casos, são específicos de uma única universidade oudomínio, não contemplam políticas acadêmicas ou simplificam a prática segmentando o conhecimento. Este trabalho propõe um protocolo para a implementação curricular do BIM semelhante aoda indústria, considerando aspectos de processo, tecnologia e políticas alinhados com a missão da instituição de ensino e com as competências existentes. Pesquisa-ação foi o método utilizado. Três ações foram realizadas: (1) proposição, (2) sistematização e (3) aplicação. As ações foram realizadas em ciclos de forma incremental, resultando em (1) diretrizes, (2) ferramentas de apoio e (3) planos de implementação. Duas universidades brasileiras participaram de estudos-piloto do Projeto Construa Brasil. Os estudos-piloto inspiraram uma rede de células BIM que aplicaram as diretrizes curriculares de implementação BIM em larga escala. As diretrizes mostraram-se genéricas e abrangentes, orientando a transformação com base empírica para a tomada de decisão dos acadêmicos. A facilitação de um especialista BIM foi confirmada como fator essencial de sucesso. Observa-se que, mesmo com uma tímida introdução de competências BIM em um escopo limitado de soluções de engenharia, o impacto na maturidade BIM do currículo é significativo. tornouse tornou se superior entanto casos oudomínio conhecimento indústria processo existentes Pesquisaação Pesquisa ação utilizado 1 (1 proposição 2 (2 3 (3 aplicação incremental estudospiloto estudos piloto Brasil escala mostraramse mostraram abrangentes acadêmicos sucesso Observase Observa engenharia significativo (

Abstract: The Intensity-Duration-Frequency (IDF) curves are a way to visualize and represent extreme hydrometeorological rainfall events. In this article, an analysis of convective rainfall events recorded at the La Piedra Meteorological Station, Villa Clara, Cuba, was conducted. To develop IDF curves, the 2006-2019 time series was analyzed. A partial duration series was generated, including intervals from 20 minutes to 4320 minutes, subjected to an outlier detection process. The series was divided into two categories: one for durations ≤ 720 minutes and another for durations > 720 minutes. The resulting series underwent non-parametric tests to assess their independence, randomness, homogeneity, and seasonality. Subsequently, they were fitted to the Generalized Pareto probability distribution and to a parametric equation of the Montana model, and then the curves were plotted for return periods of 10, 50 and 100. The Montana model led to obtaining correlation coefficients greater than 0.90 compared to the other methods used, significantly improving the quality of the fit in both categories. This research provides information to understand and plan the management of intense climatic phenomena and adequate risk management in an area where such studies are lacking, facilitating access to crucial data essential in the design and execution of hydraulic engineering projects in the region.

Resumen: Las curvas de Intensidad-Duración-Frecuencia (IDF) son una manera de visualizar y representar los eventos hidrometeorológicos extremos de lluvia. En este artículo se llevó a cabo un análisis de eventos de lluvias convectivas registrados en la Estación Meteorológica La Piedra, Villa Clara, Cuba. Para desarrollar curvas IDF se analizó la serie temporal 2006-2019. Se generó una serie de duración parcial que incluyó intervalos de 20 minutos hasta 4320 minutos, sometiéndola a un proceso de detección de datos anómalos. La serie se dividió en dos categorías: una para duraciones ≤ 720 minutos y otra para duraciones > 720 minutos. Las series resultantes se sometieron a pruebas no paramétricas para evaluar su independencia, aleatoriedad, homogeneidad y estacionalidad. Posteriormente, se procedió a ajustarlas a la distribución probabilística Generalizada de Pareto y a una ecuación paramétrica del modelo de Montana. Luego se grafica la representación de las curvas para períodos de retorno de 10, 50 y 100 años. El modelo de Montana condujo a la obtención de coeficientes de correlación superiores a 0.90 y a los demás métodos utilizados, mejorando significativamente la calidad del ajuste en ambas categorías. Esta investigación aporta información para comprender y planificar la gestión de fenómenos climáticos intensos, así como para una adecuada gestión de riesgos en una zona donde no se cuenta con este tipo de estudios. Asimismo, facilita el acceso a datos cruciales que resultan fundamentales en el diseño y ejecución de proyectos de ingeniería hidráulica en la zona.

ABSTRACT As a result of the COVID 19 pandemic, a set of modifications were implemented in the way it was taught. Higher education institutions in Chile were not immune to this phenomenon, and to this scenario was added a set of trends that had already been raising the need to review didactics, in terms of what and how it is taught. Different initiatives led to the development and implementation of didactic strategies that sought to solve the challenges faced by the educational system. Even though innumerable articles referring to the implementation of these didactic innovations have appeared, the evidence regarding the impact of their adaptations remains scarce. The objective of this research is to evaluate the impact of the use of the Case Method on the academic performance of the students of the calculus subject of the Business Administration Engineering degree at a Chilean higher education institution in an online context. through a difference-in-differences model using control groups generated with the Propensity Score Matching technique. The results show a positive and statistically significant effect on student grades.

RESUMEN Producto de la pandemia de COVID 19 se implementaron un conjunto de modificaciones en la forma cómo se enseñaba. Las instituciones de educación superior en Chile no estuvieron ajenas a ese fenómeno, y a este escenario se sumó un conjunto de tendencias que ya venían planteando la necesidad de revisar la didáctica, en cuánto al qué y al cómo se enseña. Diferentes iniciativas llevaron al desarrollo e implementación de estrategias didácticas que buscaron resolver los desafíos que enfrentaba el sistema educativo. Aun cuando han surgido innumerables artículos referidos a la implementación de estas innovaciones didácticas, la evidencia respecto del impacto de sus adaptaciones permanece escasa. El objetivo de la presente investigación es evaluar el impacto del uso del Método del Caso en el rendimiento académico de los estudiantes de los estudiantes de la asignatura de cálculo de la carrera Ingeniería en Administración de Empresas de una institución de educación superior chilena en un contexto online mediante un modelo de diferencias en diferencias usando grupos de control generados con la técnica de Propensity Score Matching. Los resultados muestran un efecto positivo y estadísticamente significativo en las calificaciones de los estudiantes.

ABSTRACT • The possible production of fructo-oligosaccharides from sucrose was evaluated in the Base Business Unit (UEB) “Ignacio Agramonte'”, which currently produces sorbitol, with low exploitation of the installed capacity, due to lack of glucose. There was an opportunity in infrastructure, time and labor to convert the entity into a multipurpose plant. A simulation model of the technology for the production of fructo-oligosaccharide syrup from sucrose was developed, based on the enzymatic transformation of sucrose into fructo-oligosaccharides, using the recombinant enzyme 1-SST (1-sucrose: sucrose fructosyltransferase) expressed in Pichia pastoris, obtained at the Center for Genetic Engineering and Biotechnology at Sancti Spiritus. Model validation yielded relative errors lesser than 5 %. Two improvement alternatives were evaluated based on increasing the production of FOS by using the actual installed capacity in the sorbitol factory (alternative 1) and also increasing the initial concentration of the sucrose solution (alternative 2). Feasibility of the alternatives was evaluated by comparing the annual net cash income (Anci) and expenses. Alternative 2 was the best, producing 841,5 t of fructo-oligosaccharides in 90 working days, with a benefit/cost ratio of 1,2.

RESUMEN • Se evaluó la posibilidad de incorporar la produccón de fructo-oligosacáridos a partir de sacarosa en la Unidad Empresarial de Base (UEB) “Ignacio Agramonte” que produce actualmente sorbitol, con un bajo aprovechamiento de la capacidad instalada por falta de glucosa, existiendo oportunidad en infraestructura, tiempo y mano de obra para convertir la entidad en una planta multipropósito. Se desarrolló un modelo de simulación de la tecnología de producción de sirope de fructo-oligosacáridos a partir de sacarosa, basada en la transformación enzimática de la sacarosa en fructo-oligosacáridos, utiizando la enzima recombinante 1-SST (1-sacarosa: sacarosa fructosiltransferasa) expresada en Pichia pastoris, obtenida en el Centro de Ingeniería Genética y Biotecnología de Sancti Spiritus. La validación del modelo arrojó errores relativos menores que el 5 %. Se evaluaron dos alternativas de mejoras a partir de aumentar la producción de FOS al utilizar la capacidad real instalada en la fábrica de sorbitol (alternativa 1) y además aumentar la concentración inicial de la solución de sacarosa (alternativa 2). Se evaluó la factibilidad de las alternativas al comparar la ganancia anual después de impuestos (Anci) y los egresos. La alternativa 2 resultó la mejor, produciéndose con ella 841,5 t de fructo-oligosacáridos en 90 días de trabajo, con una relacion beneficio / costo de 1,2.

ABSTRACT The design and visualization of the distribution of atoms in a fraction of space through the application of software allows us to increase the understanding of the structure of materials and the elaboration of theoretical propositions. The purpose of this work was to develop a procedure for the application of the GeoGebra 3D software as a tool for designing crystalline structures, from the Mathematics subject for Chemical Engineering students. A workshop called GeoCristal was held to reflect experiences on the use of GeoGebra 3D. Based on a sequence of tasks, the students designed a BCC crystal structure related to alpha iron in the software. The experience demonstrated the usefulness of the software for the design of crystalline structures. It made possible to promote and systematize essential contents of Materials Engineering. Managed to increase students' motivation for Mathematics. The study reflected the importance of the use of ICTs and basic subjects in the training of chemical engineers.

RESUMEN El diseño y visualización de la distribución de los átomos en una fracción del espacio mediante la aplicación de software, permite elevar la comprensión de la estructura de los materiales y la elaboración de proposiciones teóricas. El propósito de este trabajo consistió en desarrollar un procedimiento para la aplicación del software GeoGebra 3D como herramienta de diseño de estructuras cristalinas, desde la asignatura de Matemática para estudiantes de Ingeniería Química. Se realizó un taller denominado GeoCristal para reflejar las experiencias sobre el empleo de GeoGebra 3D. A partir de una secuencia de tareas, los estudiantes diseñaron en el software una estructura cristalina BCC relacionada con el hierro alfa. La experiencia demostró la utilidad del software para el diseño en estructuras cristalinas. Permitió fomentar y sistematizar contenidos imprescindibles de la Ingeniería de los Materiales. Logró aumentar la motivación de los estudiantes por las Matemáticas. El estudio reflejó la importancia del uso de las TICs y de las asignaturas básicas en la formación del ingeniero químico.

ABSTRACT International Academic Missions (MAI) are framed as academic mobility within the framework of the internationalization process carried out in Higher Education Institutions. The objective of this work is to know the perception of the participants of a private university in Paraguay regarding their experience in the International Academic Mission carried out in the city of Corrientes-Argentina, 2023. The work presented a quantitative, design approach non-experimental cross-sectional and descriptive scope. The analyzed population consisted of 37 people as well as the sample. The inclusion criteria were having participated in the MAI experience, belonging to the Marketing and Advertising, Business Administration and Commercial Engineering majors of the university analyzed and agreeing to complete the survey. The survey was used as data collection through a 27-question questionnaire sent via WhatsApp in September 2023. The most relevant results are: the Organization dimension (x̄=4.92) and Destination of mobility (x̄=4.91) They had the highest score while the lowest corresponded to the Duration of the experience dimension (x̄=4.41). Likewise, the most notable items were Q11 “Rate the interaction with Paraguayan teachers” and P13 “Rate the interaction with Paraguayan managers”, both with (x̄=4.97). It is worth mentioning that the lowest corresponded to P5 “The 4 (four) days of stay have been sufficient” (x̄=4.03). It is concluded that the participants are very satisfied with the MAI carried out in Corrientes.

RESUMEN Las Misiones Académicas Internacionales (MAI) se enmarcan como movilidad académica en el marco del proceso de internacionalización llevada a cabo en las Instituciones de Educación Superior. El objetivo del presente trabajo es conocer la percepción de los participantes de una universidad privada de Paraguay con respecto a su experiencia en la Misión Académica Internacional llevada a cabo en la ciudad de Corrientes-Argentina, 2023. El trabajo presentó un enfoque cuantitativo, de diseño no experimental de corte transversal y alcance descriptivo. La población analizada estuvo constituida por 37 personas como así la muestra. Los criterios de inclusión fueron haber participado de la experiencia MAI, pertenecientes a las carreras de Marketing y Publicidad, Administración de Empresas e Ingeniería Comercial de la universidad analizada y estar de acuerdo en completar la encuesta. Se utilizó la encuesta como recolección de datos mediante un cuestionario de 27 preguntas enviado vía WhatsApp en septiembre de 2023. Los resultados más relevantes son: la dimensión Organización (x̄=4,92) y Destino de la movilidad (x̄=4,91) tuvieron la mayor puntuación mientras que la más baja correspondió a la dimensión Duración de la experiencia (x̄=4,41). Asimismo, los ítems más resaltantes fueron la P11 “Califica la interacción con docentes paraguayos” y P13 “Califica la interacción con gestores paraguayos”, ambos con (x̄=4,97). Cabe mencionar que las más bajas correspondió a la P5 “Los 4 (cuatro) días de estancia han sido suficientes” (x̄=4,03). Se concluye que los participantes se encuentran Muy satisfechos con la MAI realizada a Corrientes.

Resumo La edificación del conocido como aljibe del conde de Tendilla es uno de los primeros proyectos que se acometen en la Alhambra de Granada como parte del proceso relacionado con su habitabilidad. De este modo, desde 1492 a 1495 se operaron en la Alhambra construcciones para que la población cristiana pudiese resistir un largo asedio. Las obras de adecuación se desarrollaron en dos líneas, por un lado, la instalación de una artillería en todo el conjunto de murallas, en torres y puertas, y, por otro, la adopción de medidas ante un hipotético sitio, destacando la refortificación de la Alcazaba, y la construcción del aljibe al que nos venimos refiriendo. En el recinto de la fortaleza se va a aspirar a la configuración de una auténtica ciudad con obras de un elevado contenido simbólico, detrás de las cuales se encuentran figuras claves como Íñigo López de Mendoza, el conde de Tendilla. Este noble se va a convertir en uno de los ideólogos del importante cambio que sufrió la zona palatina nazarí en relación con el papel que desempeñó en el marco de la nueva monarquía.

Abstract The construction of the cistern of the Count of Tendilla, as it is known, was one of the first projects undertaken in the Alhambra of Granada as part of the process related to its habitability. From 1492 to 1495, constructions were carried out in the Alhambra to enable the Christian population to withstand a long siege. The adaptation works were developed in two lines, on one hand, the installation of artillery throughout the walls, towers and gates, and on the other, the adoption of measures against a hypothetical siege, highlighting the refortification of the Alcazaba and the construction of the aforementioned cistern. In the fortress complex, the aim was to create a genuine city with works of high symbolic content, behind which key figures such as Íñigo López de Mendoza, the Count of Tendilla, were involved. This nobleman became one of the ideologists of the significant change that the Nasrid palatine area underwent in relation to the role it played in the framework of the new monarchy.