Abstract Type 2 Diabetes Mellitus (T2DM) is a set of metabolic disorders that increase the risk of multisystemic diseases. In Mexico, Clinical Practice Guidelines (CPG) have been proposed for the healthcare of people with T2DM, from prevention to rehabilitation. However, although these guidelines emphasize the active participation of patients in their treatment to enhance treatment adherence, the necessary information on the procedures has not been provided. Therefore, the aim of this paper is to propose Human-Centered Design Thinking (HCDP) as a strategy for this purpose. The steps that constitute this methodology are described, as well as the results found in the international literature. The coherence of the HCDP with Mexican CPG recommendations is discussed, as is the importance of the methodological clarity provided by this model to improve treatment adherence in people with T2DM.

Resumen La diabetes mellitus tipo 2 (DMT2) es un conjunto de desórdenes metabólicos que aumenta el riesgo de afecciones multisistémicas. En México se han propuesto Guías de Práctica Clínica (GPC) para la atención de la salud en personas con DMT2, que van desde la prevención hasta la rehabilitación. Sin embargo, a pesar de enfatizar la participación activa de los pacientes en sus tratamientos para mejorar la adherencia al tratamiento, no cuenta con procedimientos claros. Por ello, el objetivo de este trabajo es proponer el pensamiento de diseño centrado en la persona (PDCP) como una estrategia para esta meta. Se describen los pasos que integran esta metodología, así como los resultados observados en la literatura internacional. Se discute la coherencia del PDCP con las recomendaciones de las GPC mexicanas, y la importancia de la claridad metodológica que brinda este modelo para mejorar la adherencia al tratamiento en personas con DMT2.

Abstract Objective: This systematic review aims to clarify COVID-19’s impact on the onset of T2D in adults. Material and methods: Following PRISMA guidelines, this systematic review sourced data from multiple databases from 2019 to April 20th, 2023. Two reviewers handled screening, with a third-party resolving disagreement. The focus was on COVID-19 cases with post-infection T2D symptoms persisting for two or more months. Exclusions included those outside the 18-70 age range, prior T2D history, pregnancy, and animal studies. Rayyan software facilitated article screening, STATA 18 performed meta-analysis, and bias was assessed using JBI tools. The study is registered in PROSPERO (ID: CRD42023414096). Results: A total of 173 articles were retrieved, of which 23 (11.6%) remained for extraction. 13 cohort studies with 11.551.026 participants were included for the meta-analysis, which found that the COVID-19 population had 1.4 greater risk of being diagnosed with T2D in comparison with the population without COVID-19or with other respiratory diseases. The other study designs were narratively analyzed, describing similar results as the meta-analysis. Discussion: New onset T2D is a potential consequence of LC. While T2D increases COVID-19 complications, the relationship appears bidirectional. Given the novelty of the topic and potential newer studies, further reviews are needed to understand LC’s impact on chronic diseases like T2D globally. Further studies should be carried out on this specific topic that could raise the burden of T2D between all the other symptoms that may be caused by LC. In addition, it is necessary to adapt the interventions according to each country’s possibilities.

Resumen Objetivo: El objetivo de esta revisión es aclarar el impacto del COVID-19 en nuevos diagnósticos de DM2. Material y Métodos: Esta revisión se elaboró en base a las guías PRISMA. Dos revisores realizaron una búsqueda en bases de datos, incluyendo artículos desde el 2019 hasta el 20 de abril de 2023 en adultos, diagnosticados al menos una vez con COVID-19, sin diagnóstico previo de DM2. Excluyeron: embarazadas, niños y diabetes mellitus I. Esta revisión se registró en PROSPERO (ID: CRD42023414096) el 6 de abril de 2023. Resultados: Un total de 173 artículos se obtuvieron luego de la búsqueda, de los cuales 23 (11,6%) quedaron para extracción. 13 estudios de cohorte con 11.551.026 participantes se incluyeron en el metaanálisis, que encontraron que la población que tuvo COVID tiene un 1,4 veces más riesgo de ser diagnosticados con DM2 en comparación a quienes no tuvieron el diagnóstico o fueron diagnosticados con otra patología respiratoria. Los diseños de estudio se describieron narrativamente, describiendo resultados similares a los del metaanálisis. Discusión: El nuevo diagnóstico de DM2 es una potencial consecuencia de LC. Mientras aumenta la DM2, aumentan las complicaciones de COVID-19, la relación aparenta ser bidireccional. Ya que estos hallazgos son medianamente recientes, no existe mucha evidencia disponible al respecto, por lo tanto, se requiere un mayor número de estudios al respecto, además de la creación de nuevas políticas de salud pública ad hoc a las posibilidades de cada país.

ABSTRACT Introduction: Diabetes mellitus is a public health issue affecting an increasing number of workers, representing a disease exacerbated by work with a high social, economic, and personal cost. The nature of the work performed, coupled with occupational risks in a hospital setting, significantly contribute to the disease's progression. This study aims to address the impact of this disease on work and the role of Occupational Health in the prevention of exposure to occupational risk factors in the hospital environment, which can contribute to the metabolic imbalance of type I diabetes mellitus. Methodology: The methodology included search in PubMed, Science Direct, and Google Scholar databases, using keywords such as "diabetes mellitus, occupational medicine, risk factors and occupational health”. Filters were applied, considering publications from 2010 to 2024, totaling 463 works. Exclusion criteria focused on non-diabetes-related diseases, exclusive focus on Type II, and non-occupational approaches. Articles on diabetes and occupational health and safety published in Revista Portuguesa de Saúde Ocupacional were also considered, in a total of five studies. Sources also included Direção Geral de Saúde Clinical Guidance, a national epidemiological study, and a technical manual on workplace diabetes, totaling 30 references in the discussion. Results: The authors report two cases of healthcare professionals from a hospital unit, both diagnosed with Type I Diabetes at the age of five. Case 1: A 35-year-old healthcare assistant with a history of depressive syndrome and recent diabetic retinopathy diagnosis. Case 2: A 57-year-old nurse with diabetic retinopathy, nephropathy, neuropathy, undergoing treatment for osteomyelitis of the right big toe, without cardiovascular changes. In both they work or have worked in shifts, including night shifts, engaging in physically demanding tasks. Discussion/Conclusion: Diabetes is a chronic disease requiring continuous medical care and patient education, alongside support in preventing acute complications and reducing the risk of chronic complications. The incidence of new Type I Dm cases is higher between 12-14 years. During the transition to adulthood and entry into the job market, patients face disease stigma, treatment management challenges, and psychosocial workplace-related issues. Implementing preventive measures and monitoring these workers should help reduce work absenteeism, productivity loss, and income loss for the worker.

RESUMO Introdução: A Diabetes mellitus é um problema de Saúde Pública que afeta um número crescente de trabalhadores. Pode ser considerada uma doença agravada pelo trabalho com um elevado custo social, económico e pessoal. O tipo de trabalho realizado e as exposições a riscos laborais em contexto hospitalar, podem contribuir para a sua progressão, segundo alguns autores. Este trabalho pretende abordar o impacto desta patologia no trabalho e o papel da Saúde Ocupacional na evicção da exposição a fatores de risco laborais, em ambiente hospitalar, que contribuem para o descontrolo metabólico da Diabetes Melitus tipo I. Pretende-se identificar as exposições laborais que podem constituir fatores de risco modificáveis, interferem com a aptidão para o trabalho, podem aumentar a frequência de acidentes laborais e acelerar a progressão crónica da doença. Metodologia: Na metodologia de pesquisa e seleção de estudos utilizou as bases de dados PubMed, Science Direct e Google Scholar, com as palavras-chave “diabetes mellitus, occupational medicine, risk factors, occupational health”. Aplicaram-se filtros de revisão e revisão sistemática, considerando publicações de 2010 a 2024, totalizando 463 trabalhos. Critérios de exclusão incidiram em doenças não relacionadas à diabetes, exclusividade na tipo II e abordagens não ocupacionais. Foram ainda considerados os artigos sobre diabetes e saúde e segurança no trabalho publicados na Revista Portuguesa de Saúde Ocupacional, num total de cinco estudos. Incluíram-se a Norma de Orientação Clínica da DGS, um estudo epidemiológico nacional e um caderno técnico sobre diabetes no local de trabalho, totalizando 30 fontes na discussão. Descrição dos casos: Os autores reportam dois casos de profissionais de saúde de uma unidade hospitalar, ambos com diagnóstico de Diabetes tipo I aos cinco anos de idade. Caso 1: Uma auxiliar de ação médica de 35 anos, com antecedentes pessoais de síndrome depressivo e diagnóstico recente de retinopatia diabética. Caso 2: Uma enfermeira de 57 anos com retinopatia e nefropatia diabética, neuropatia, em tratamento para uma osteomielite do 1º dedo do pé direito, sem alterações cardiovasculares. Ambas trabalham ou trabalharam por turnos, com trabalho noturno e com tarefas fisicamente exigentes. Discussão/Conclusão: A diabetes é uma doença crónica que requer cuidados médicos contínuos e educação do doente, juntamente com apoio na prevenção de complicações agudas e redução do risco de complicações crónicas. A incidência de novos casos de Dm tipo I é maior entre os 12-14 anos. Na transição para a idade adulta e entrada no mercado laboral, os doentes podem ser sujeitos ao estigma da doença, ter dificuldade na gestão do tratamento e/ou desafios psicossociais relacionados com o trabalho. A instituição de medidas preventivas e monitorização destes trabalhadores deverá ajudar a reduzir o absentismo laboral, a perda de produtividade e a perda de rendimento para o trabalhador.

ABSTRACT Foundation: Diabetes mellitus has been considered by the World Health Organization a serious health problem to be solved throughout the world. Its prevention and educating about it is essential. Objective: To describe an educational intervention on type 2 diabetes mellitus results in patients with risk factors. Methods: Intervention study, with a before and after design, which included 120 patients over 18 years of age with diabetes mellitus risk factors, belonging to Medical Office No. 6, in Nuevitas, Camagüey province. A survey was applied to measure the level of knowledge, before and after the educational intervention. The variables: age, educational level, knowledge about diabetes mellitus, risk factors and prevention were analyzed. Results: Women, university education level and those over 60 years of age predominated. At the beginning of the study, around 75% of the participants showed fair or low knowledge about diabetes mellitus, risk factors and prevention. All of these parameters increased above 85% after the intervention. Conclusions: A notable increase in knowledge about diabetes mellitus, its risk factors and how to prevent it was achieved. These types of strategies, applicable from the primary level of care, imply a benefit in the prevention of this and other non-communicable diseases.

RESUMEN Fundamento: La diabetes mellitus ha sido considerada por la Organización Mundial de la Salud un grave problema de salud por resolver en todo el orbe. Su prevención resulta imprescindible, y educar al respecto es fundamental. Objetivo: Describir resultados de una intervención educativa sobre diabetes mellitus tipo 2 en pacientes con factores de riesgo. Métodos: Estudio de intervención, con diseño de antes y después, que incluyó a 120 pacientes mayores de 18 años con factores de riesgo de diabetes mellitus, pertenecientes al Consultorio Médico No. 6, en Nuevitas, provincia de Camagüey. Se aplicó una encuesta para medir el nivel de conocimientos, antes y después de la intervención educativa. Se analizaron las variables edad, nivel de escolaridad, conocimiento sobre diabetes mellitus, factores de riesgo y prevención. Resultados: Predominaron las mujeres, el nivel de escolaridad universitario y los mayores de 60 años. Al inicio del estudio, alrededor del 75 % de los participantes mostró regular o bajo conocimiento sobre diabetes mellitus, factores de riesgo y prevención. Todos estos parámetros aumentaron por encima del 85 % después de la intervención. Conclusiones: Se logró un incremento notable de los conocimientos acerca de la diabetes mellitus, sus factores de riesgo y cómo prevenirla. Este tipo de estrategias, aplicables desde el nivel primario de atención, implican un beneficio en la prevención de esta y otras enfermedades no transmisibles.

Abstract Objective: To know the scientific evidence to identify patterns of changes in lifestyles during childhood and their association with various anthropometric parameters in infants caused during confinement by COVID-19. Materials and methods: A systematic analysis was carried out following the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guide in the PubMed and Google Scholar databases, the keywords used were diabetes mellitus tipo 2 or diabetes mellitus type II, hipertensión or hypertension, cuarentena or quarantine, covid-19, infantes or child, estilos de vida saludables or healthy lifestyles, sedentarismo or sedentarism, comportamientos alimentarios or eating behaviors. The search was carried out from April 2019 to June 2022. Results: The search yielded 221 articles, only 5 articles met the inclusion, exclusion and quality criteria, which show that the COVID-19 confinement caused changes in lifestyles. life that were mainly associated with a sedentary lifestyle during childhood. Conclusions: There is little information on the effects that COVID-19 confinement has caused on the lifestyles of infants, the existing information shows changes in pro-healthy eating habits in infants and decreased physical activity; therefore, activities aimed at guardians or responsible adults are recommended so that they can supervise feeding and improve nutrition, as well as carry out activities that encourage physical activity.

Resumen Objetivo: Conocer las evidencias científicas que evidencian cambios en los patrones de estilos de vida durante la infancia y su asociación con el confinamiento causado por la COVID-19. Materiales y métodos: Se realizó un análisis sistemático siguiendo los lineamientos de la guía Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) en las bases de datos de PubMed y Google Académico, las palabras claves utilizadas fueron diabetes mellitus type II o diabetes mellitus tipo II, hypertension o hipertensión, quarantines o cuarentena, covid 19, infants o infantes, child o niños, healthy lifestyle o estilo de vida saludable, sedentary behavior o sedentarismo, feeding behaviors o comportamientos alimentarios. La búsqueda se realizó de abril 2019 a junio 2022. Resultados: La búsqueda arrojó 221 artículos, sólo 5 artículos cumplieron los criterios de inclusión, exclusión y criterios de calidad, los cuales muestran que el confinamiento por COVID-19 causó cambios en los estilos de vida que se asociaron principalmente al sedentarismo durante la infancia. Conclusiones: Existe poca información sobre los efectos que ha causado el confinamiento por la COVID-19 en los estilos de vida de los infantes, la existente muestra cambios en los hábitos alimentarios pro-saludables en infantes y disminución de la actividad física; por lo que se recomiendan actividades dirigidas a los tutores o adultos responsables para que supervisen la alimentación y la mejora de la nutrición, así como realizar actividades que fomenten la actividad física.

El consenso chileno sobre el uso de inhibidores de SGLT-2 (iSGLT-2) en la práctica clínica, elaborado conjuntamente por las sociedades Chilenas de Cardiología, Diabetes, Medicina Familiar y Nefrología, recomienda fuertemente el uso de estos fármacos en personas con insuficiencia cardíaca y fracción de eyección reducida, diabetes mellitus tipo 2 para prevención de eventos cardiovasculares y evitar la progresión de enfermedad renal crónica. En insuficiencia cardíaca con fracción de eyección conservada o levemente reducida, y enfermedad renal crónica sin diabetes, el consenso sugiere el uso de iSGLT-2. Se destaca la importancia de combinar iSGLT-2 con IECAs o ARA-II en enfermedad renal crónica, y se recomienda su uso en reemplazo de sulfonilureas como segunda línea para control glicémico en diabetes tipo 2. El consenso enfatiza la necesidad de estrategias para optimizar el diagnóstico, mejorar la adherencia y educar sobre los beneficios más allá del control glicémico. Se discuten consideraciones de seguridad y costo-efectividad para una implementación priorizada según la evidencia. El documento resalta la importancia de la colaboración multidisciplinaria y la generación de evidencia local para aprovechar al máximo el potencial de estos fármacos en el manejo de condiciones cardiometabólicas complejas en Chile.

The Chilean consensus on the use of SGLT-2 inhibitors (iSGLT-2) in clinical practice, jointly developed by the societies of Cardiology, Diabetes, Family Medicine, and Nephrology, strongly recommends the use of these drugs in people with heart failure with reduced ejection fraction, type 2 diabetes mellitus for prevention of cardiovascular events, and chronic kidney disease. In heart failure with preserved or mildly reduced ejection fraction, and chronic kidney disease without diabetes, the consensus suggests the use of iSGLT-2. The importance of combining iSGLT-2 with ACE inhibitors or ARBs in chronic kidney disease is highlighted, and their use is recommended to replace sulfonylureas as a second-line treatment for glycemic control in type 2 diabetes. The consensus emphasizes the need for strategies to optimize diagnosis, improve adherence, and educate about benefits beyond glycemic control. Safety and cost-effectiveness considerations for prioritized implementation according to evidence are discussed. The document highlights the importance of multidisciplinary collaboration and the generation of local evidence to maximize the potential of these drugs in the management of complex cardiometabolic conditions in Chile.

Abstract Diabetes is a metabolic disorder with no definite treatment, but it can be controlled by changing lifestyle and diet. Consumption of high-fiber and nutrient-rich foods including vegetables have been shown to reduce risks of obesity and Type II Diabetes Mellitus (T2DM). Also, many herbal plants have been associated with reduced risks of T2DM because of their composition of secondary metabolites. Antioxidant activities of some secondary metabolites have potent inhibitory effects against inflammation linked with insulin resistance and oxidative stress. More than 800 known medicinal plants are used to control diabetes and its relevant complications. However, variations in preharvest factors including plant genotype, growing medium properties, climatic factors, and management practices can influence plant growth and their accumulation of phytochemicals with health-promoting properties. However, the effects of these preharvest factors on the antidiabetic properties of plant secondary metabolites are neither explicit nor easily accessible in the literature. Therefore, this review aims to document recent studies that reported on under-exploited medicinal plants with antidiabetic properties. We reviewed several important preharvest factors that can potentially affect the synthesis of phytoconstituents which possess antidiabetic properties. This review will help identify gaps for future research in phytomedicine and functional foods. treatment diet highfiber high fiber nutrientrich nutrient rich T2DM. TDM . T DM (T2DM) Also stress 80 complications However genotype healthpromoting health promoting literature Therefore underexploited under exploited (T2DM 8

Resumo O diabetes é um distúrbio metabólico sem tratamento definido, todavia pode ser controlado a partir de mudanças no estilo de vida e na alimentação. O consumo de alimentos ricos em fibras e nutrientes, incluindo vegetais, demonstrou reduzir os riscos de obesidade e Diabetes Mellitus tipo II (DM2). Além disso, muitas plantas herbáceas têm sido associadas a riscos reduzidos de DM2 devido à sua composição de metabólitos secundários. As atividades antioxidantes de alguns metabólitos secundários têm efeitos potentes de inibição contra inflamações associadas à resistência à insulina e ao estresse oxidativo. Existem mais de 800 plantas medicinais conhecidas utilizadas no controle do diabetes e suas complicações. No entanto, variações nos fatores de pré-colheita, incluindo genótipo da planta, propriedades do meio de cultivo, fatores climáticos e práticas de manejo, podem influenciar em seu desenvolvimento e seu acúmulo de fotoquímicos com propriedades promotoras. Apesar disso, os efeitos desses fatores de pré-colheita nas propriedades antidiabéticas de metabólitos secundários de plantas não são explícitos nem facilmente acessáveis na literatura. Portanto, esta revisão tem como objetivo documentar estudos recentes que relataram plantas medicinais subexploradas com propriedades antidiabéticas. Revisamos diversos fatores pré-colheita importantes que podem afetar potencialmente a síntese de fitoconstituintes que possuem propriedades antidiabéticas. Assim, esta revisão auxiliará na identificação de lacunas para pesquisas futuras em fitomedicina e alimentos funcionais. definido alimentação nutrientes vegetais DM2. DM . (DM2) disso oxidativo 80 complicações entanto précolheita, précolheita pré colheita, colheita planta cultivo manejo promotoras literatura Portanto Assim funcionais (DM2 8 (DM

Abstract Simultaneous bilateral rupture of the quadricipital tendon is an extremely rare lesion. We report a case of this injury after low-energy trauma in a patient with type-II diabetes mellitus. Both knees were surgically approached in the same surgical procedure. Early rehabilitation is essential for the adequate functional recovery of the knee. The aim of the present report was to describe an atypical case of this type of injury after minimal trauma, as well as to detail the surgical technique used to treat it. lesion lowenergy low energy typeII II mellitus procedure knee it

Resumo A ruptura bilateral simultânea do tendão do quadríceps é uma lesão extremamente rara. Relatamos um caso desta lesão após trauma de baixa energia em paciente portador de diabetes mellitus do tipo II. O diagnóstico é essencialmente clínico, e requer tratamento precoce. Os dois joelhos foram abordados cirurgicamente no mesmo ato operatório. A reabilitação precoce é fundamental para a recuperação funcional adequada do joelho. O objetivo deste relato foi descrever um caso atípico deste tipo de lesão após trauma mínimo, bem como detalhar a técnica cirúrgica utilizada para o tratamento. rara II clínico operatório joelho mínimo

Abstract Background: Recent studies show Silent Myocardial Infarction (SMI) as a quite frequent event. However, regarding severe tertiary care patients that frequently present consequences of Coronary Artery Disease (CAD) and Left Ventricular Dysfunction (LVD), the occurrence of this manifestation is unexpected and its associated factors aren't clear in the literature. Aim: To compare clinical, laboratorial, ventricular and angiographic factors between silent and classical presentation of MI in patients with CAD and LVD. Methods: Patients with multivessel CAD with over 70 % obstructive lesions and LVD with EF less than 35 % were evaluated for MASS VI trial and later included in the present study. The ventricular function and coronary assessment were measured by echocardiography and SYNTAX score, respectively. The population was stratified in a SMI group and Clinically Manifested Myocardial Infarction (CMMI) group based on MI presentation for a comparison of medical parameters. Results: From 132 patients, 47 (35.6 %) were classified as SMI and 85 (64.4 %) as CMMI. No differences were observed between groups regarding age, sex, diabetes mellitus, SYNTAX score, or collateral circulation. Higher proportion of NYHA II classification, inferior wall MI and lower creatinine clearance were found in SMI group. After multivariate analysis, peripheral diabetic neuropathy (OR = 4.6 [1.1-12.7] p = 0.032) and inferior wall MI (OR = 4.1 [1.5-11.4] p = 0.007) were significantly associated with SMI. Conclusion: Peripheral diabetic neuropathy and inferior wall MI were associated with SMI presentation. Overall, associated factors tend to be similar comparing SMI and CMMI, but in the specific population of diabetic patients with chronic neuropathy a special care should be taken. Background (SMI event However (CAD LVD, , (LVD) arent aren t literature Aim clinical laboratorial Methods 7 3 study score respectively CMMI (CMMI parameters Results 13 4 35.6 356 6 (35. 8 64.4 644 64 (64. age sex mellitus circulation classification analysis OR 46 4. 1.112.7 11127 1.1 12.7 1 12 [1.1-12.7 0.032 0032 0 032 41 1.511.4 15114 1.5 11.4 5 11 [1.5-11.4 0.007 0007 007 Conclusion Overall taken (LVD 35. (35 64. (64 112 1.112. 1112 1. 127 12. [1.1-12. 0.03 003 03 511 1.511. 1511 15 114 11. [1.5-11. 0.00 000 00 (3 (6 1.112 111 [1.1-12 0.0 51 1.511 151 [1.5-11 ( 1.11 [1.1-1 0. 1.51 [1.5-1 [1.1- [1.5- [1.1 [1.5 [1. [1 [

RACIONAL: Para reduzir o risco de regurgitação durante a anestesia para procedimentos eletivos, os volumes gástricos residuais (VRG) têm sido tradicionalmente minimizados com jejum noturno. O jejum pré-operatório prolongado tem algumas consequências adversas e tem sido abandonado para a maioria dos procedimentos cirúrgicos, com exceção de pacientes obesos e/ou diabéticos. OBJETIVOS: O objetivo deste estudo foi avaliar o VRG em pacientes diabéticos obesos mórbidos após jejum tradicional ou abreviado. MÉTODOS Este estudo foi aprovado pelo Comitê de Ética em Pesquisa em Seres Humanos da Universidade Federal de Mato Grosso, sob o número 179.017/2012. Este é um projeto prospectivo, randomizado e cruzado em 8 pacientes diabéticos tipo II com obesidade mórbida. O VRG foi medido endoscopicamente após jejum noturno tradicional (pelo menos 8 horas) ou após jejum abreviado (6 horas para sólidos e 3 horas para uma bebida contendo água mais 25 g (12,5%) de maltodextrina). Os dados são expressos como média e variação e as diferenças foram comparadas com testes t pareados em p<0,05. RESULTADOS: A população estudada tinha 41,5 (28-53) anos de idade, peso médio de 135 (113-196) kg, índice de massa corporal (IMC) de 48,2 (40-62,4) kg/m2 e diabetes tipo II de 4,5 (1-10) anos. O VRG após o jejum abreviado foi de 21,5 (5-40) ml versus 26,3 (7-65) ml após o jejum tradicional. Essa diferença não foi significativa (p=0,82). CONCLUSÕES:  O esvaziamento gástrico em pacientes diabéticos obesos mórbidos é semelhante após jejum tradicional ou abreviado com uma bebida com carboidrato.

BACKGROUND: To reduce the risk of regurgitation during anesthesia for elective procedures, residual gastric volumes (RGV) have traditionally been minimized with overnight fasting. Prolonged preoperative fasting have some adverse consequences and has been abandoned for most surgical procedures, with the exception of obese and/or diabetic patients.  AIMS: The aim of this study was to assess the RGV in  morbidly obese diabetics patients after traditional or abbreviated fasting. METHODS: This study was approved by the Committee of Ethics in Research in Human Beings from the Federal University of Mato Grosso, number 179.017/2012. This is a prospective, randomized, and cross-over design in 8 morbidly obese type II diabetic patients. RGV was measured endoscopically after either traditional overnight fasting (at least 8 hours) or after abbreviated fasting (6 h for solids and 3 hours for a drink containing water plus 25 g (12.5%) of maltodextrin). Data are expressed as mean and range and differences were compared with paired t tests at p<0.05.  RESULTS: The study population was 41.5 (28-53) years old, with a mean weight of 135 (113-196) kg, body mass index (BMI) 48.2 (40-62.4) kg/m2, and having type II diabetes for 4.5 (1-10) years. The RGV after abbreviated fasting was 21.5 (5-40) ml vs 26.3 (7-65) ml after traditional fasting. This difference was not significant (p=0.82). CONCLUSIONS: Gastric emptying in morbidly obese diabetics patients is similar after either traditional or abbreviated fasting with a carbohydrate drink.

Resumen Introducción: Las enfermedades cardiovasculares son la principal causa de mortalidad.Desde la farmacia comunitaria (FC) es posible ayudar a los pacientes a mejorar los factores de riesgo cardiovascular (FRCV) modificables: hipertensión arterial (HTA), dislipemia, diabetes mellitus (DM), tabaquismo y obesidad. Entre los servicios profesionales farmacéuticos relacionados con la salud comunitaria se incluyen este tipo de actuaciones. El objetivo de este estudio ha sido determinar el perfil sociosanitario y farmacoterapéutico de los pacientes con RCV atendidos en la FC española, con el fin de diseñar la intervención más efectiva para ellos. Método: Se realizó un estudio descriptivo de corte transversal entre enero 2017 y febrero 2018. Utilizando un formulario de recogida de datos se registraron los correspondientes a los pacientes de cuatro FC, dos en Sevilla y dos en Badajoz (España) mediante entrevistas individualizadas. Resultados: La muestra inicial (n=100) quedó reducida a 98 pacientes, mayores (61,5±10,1 años), 51,0 % varones, con bajo nivel educativo (53,1 %) y la mayoría de ellos viviendo acompañados (87,8 %). El 74,5 % eran pacientes en prevención primaria y su nivel de RCVmoderado (2,51±1,89). HTA (83,7 %), dislipemia (64,39 %), diabetes II (38,8 %) y obesidad (52,0 %) fueron los factores más prevalentes. Casi la mitad de los pacientes (48,5 %) realizaban ejercicio físico regularmente y el 23,5 % eran fumadores. Los fármacos más consumidos fueron los modificadores de lípidos (59,4 %), antidiabéticos orales (37,5 %), antitrombóticos (32,2 %) y betabloqueantes (28,1 %), Conclusiones: La utilización de formularios encaminados a detectar las necesidades educacionales y farmacoterapéuticas de pacientes con RCV, permitirá establecer diferentes estrategias para mejorar la capacidad de gestionar su enfermedad.

Abstract Introduction: Cardiovascular diseases are the leading cause of mortality, and community pharmacy (CP) can help patients improve modifiable cardiovascular risk factors (CVRF): hypertension (HT), dyslipidaemia, diabetes mellitus (DM), smoking, and obesity. Professional pharmaceutical services related to community health include this type of action. The aim of this study was to determine the socio-health and pharmacotherapeutic profile of patients with CVR treated in Spanish CP, to design the most effective intervention for them. Method: A descriptive cross-sectional study was conducted between January 2017 and February 2018. Using a data collection form, data from patients in four CP, two in Seville and two in Badajoz (Spain) were recorded through individualised interviews. Results: The initial sample (n=100) was reduced to 98 patients, older (61.5±10.1 years), 51.0 % male, with low educational level (53.1 %) and most of them living accompanied (87.8 %). 74.5 % were patients in primary prevention and their CVR level was moderate (2.51±1.89). Hypertension (83.7 %), dyslipidaemia (64.39 %), diabetes II (38.8 %) and obesity (52.0 %) were the most prevalent factors. Almost half of the patients (48.5 %) exercised regularly and 23.5 % were smokers. The drugs most commonly used were lipid modifiers (59.4 %), oral antidiabetics (37.5 %), antithrombotics (32.2 %) and beta-blockers (28.1 %). Conclusions: The use of forms aimed at detecting the educational and pharmacotherapeutic needs of CVR patients will allow one to establish different strategies to improve their ability to manage their disease.

ABSTRACT This Article Seeks analyzes the evidence provided by strength training, verifying its influence on Type II Diabetes Mellitus by using the existing literature on this subject of study. A systematic review was carried out following the PRISMA guidelines, where the main context was strength training in patients with Mellitus II. The search was carried out in Pubmed, Embase, and Scopus databases where 7 articles were selected. The findings consistently indicated that a well-structured strength training program gradually affected some markers that identify diabetes Mellitus II when performing interventions with strength training systems in a positive way. The authors recommend control-type studies with larger samples, if possible, to verify the incidence of training in the variables mentioned in this study.

RESUMO Este artigo procura analisar as evidências fornecidas pelo treinamento de força, verificando sua influência no Diabetes Mellitus tipo II utilizando a literatura existente sobre este objeto de estudo. Foi realizada uma revisão sistemática seguindo as diretrizes PRISMA onde o principal contexto foi o treinamento de força em pacientes com Mellitus II, sendo pesquisada nas bases de dados Pubmed, Embase e Scopus onde foram selecionados 7 artigos. Os achados indicam consistentemente que o treinamento de força bem programado afeta gradualmente alguns marcadores que identificam o diabetes Mellitus II ao realizar intervenções com sistemas de treinamento de força de forma positiva. Os autores recomendam estudos do tipo controle com amostras maiores, se possível, para verificar a incidência de treinamento nas variáveis mencionadas neste estudo.

RESUMEN El presente artículo busca analizar las evidencias aportadas del entrenamiento de la fuerza comprobando su influencia en la Diabetes Mellitus tipo II utilizando la literatura existente sobre este objeto de estudio. Se realizo una revisión sistemática siguiendo las directrices PRISMA donde el principal contexto fue el entrenamiento de la fuerza en pacientes con Mellitus II, siendo buscados en bases de datos Pubmed, Embase y Scopus donde fueron seleccionados 7 artículos. Los hallazgos señalan consistentemente que el entrenamiento de la fuerza bien programado incide gradualmente en algunos marcadores que identifican la diabetes Mellitus II al realizar intervenciones con sistemas de entrenamiento de la fuerza de forma positiva. Los autores recomiendan estudios con muestras mayores en lo posible de tipo control para verificar la incidencia del entrenamiento en las variables mencionadas en este estudio.

ABSTRACT Introduction: Diabetes mellitus is a disease characterized by a sustained increase in blood glucose levels. The clinical manifestations and complications of the disease generate functional disability and affect the perception of quality of life. Glycemic control is essential to improve the health status of patients. Objective: To implement a comprehensive health intervention in patients diagnosed with type II DM residing in the Riobamba canton. Methods: Applied research was carried out, with a quasi-experimental, descriptive and longitudinal design. The universe consisted of 256 patients diagnosed with type II diabetes mellitus, of which 155 were part of the study sample. Glycemic control, nutritional status, waist circumference and level of knowledge were analyzed at the beginning and end of the intervention; as well as the general characteristics at the beginning of the study. The Wilcoxon signed rank test was used to identify whether the intervention generated changes in the study variables by comparing the results before and after the intervention. Results: Average age of 63.28 years, predominance of female patients (69.68 %) and no associated comorbidities (66.45 %). At the beginning of the study, the low level of knowledge (60.00 %), admissible glycemic control (34.19%) and waist circumference with high risk prevailed in men (37.96 %) and women (38.30 %). . After completing the study, the average level of knowledge (38.71 %), patients with normal weight (57.42 %), adequate glycemic control (34.84 %) predominated. Conclusions: the applied intervention generated positive changes in the variables studied.

RESUMEN Introducción: La diabetes mellitus es una enfermedad caracterizada por un aumento sostenido de las cifras de glucemia. Las manifestaciones clínicas y complicaciones de la enfermedad generan discapacidad funcional y afectación de la percepción calidad de vida. El control de la glucemia es fundamental para mejorar el estado de salud de los pacientes. Objetivo: Implementar una intervención de salud integral en pacientes con diagnóstico de DM tipo II residentes en el cantón Riobamba. Métodos: Se realizó una investigación aplicada, con diseño cuasiexperimental, descriptivo y longitudinal. El universo estuvo constituido por 256 pacientes con diagnóstico de diabetes mellitus tipo II, de los cuales 155 formaron parte de la muestra del estudio. Se analizaron, al inicio y final de la intervención, el control glucémico, estado nutricional, circunferencia de la cintura y nivel de conocimiento; así como las características generales al inicio del estudio. Se utilizó la prueba de rangos con signos de Wilcoxon para identificar si la intervención generó cambios en las variables de estudio comparando los resultados antes y después de la intervención. Resultados: Promedio de edad de 63,28 años, predominio de pacientes femeninas (69,68 %) y sin comorbilidades asociadas (66,45 %). Al inicio del estudio predominó el nivel de conocimiento bajo (60,00 %), control glucémico admisible (34,19 %) y circunferencia de la cintura con riesgo elevado en hombres (37,96 %) y mujeres (38,30 %). Después de terminado el estudio predominó el nivel medio de conocimiento (38,71%), los pacientes con normopeso (57,4 2%), control glucémico adecuado (34,84 %). Conclusiones: la intervención aplicada generó cambios positivos en las variables estudiadas.

RESUMEN Los trastornos metabólicos de colesterol total, glucosa y triglicéridos están directamente relacionados con la diabetes mellitus tipo 2, por lo que su detección mediante análisis clínicos confiables contribuye a la prevención de la salud y al diagnóstico de la enfermedad. En este estudio se realizó el análisis de concordancia de los resultados de colesterol, glucosa y triglicéridos obtenidos mediante el método espectrofotométrico en cuatro diferentes laboratorios de análisis clínicos de la ciudad de Riobamba, en muestras sanguíneas de voluntarios de ambos sexos entre 19 y 22 años. El colesterol y la glucosa fueron significativamente diferentes al nivel del 5%, mientras que los valores de triglicéridos no mostraron diferencia significativa. Los resultados de colesterol, glucosa y triglicéridos coincidieron en 85%, 92% y 87%, respectivamente. Las inconsistencias de los valores pueden conducir a un diagnóstico equivocado por parte de los médicos que se apoyan en las pruebas clínicas y, por tanto, a tratamientos inadecuados con el consiguiente gasto evitable para la salud pública. Entonces, será necesaria la implementación de políticas de calidad en los laboratorios clínicos, que aumenten la fiabilidad de sus resultados.

ABSTRACT Metabolic disorders of total cholesterol, glucose and triglycerides are directly related to Diabetes Mellitus Type II, so their detection by reliable clinical tests contributes to the prevention of health and the diagnosis of the disease. In this study, the concordance analysis of the cholesterol, glucose and triglyceride results obtained by the spectrophotometric method was carried out in four different clinical analysis laboratories in the city of Riobamba, in blood samples of volunteers from both sexes between 19 and 22 years old. Cholesterol and glucose were significantly different at the 5% level, while triglycerides values showed no significant difference. Cholesterol, glucose and triglyceride results coincided in 85%, 92% and 87%, respectively. Inconsistencies in values can lead to misdiagnosis by physicians relying on clinical trials and thus to inadequate treatments that entail avoidable public health costs. Then, it will be necessary to implement quality policies in clinical laboratories, which increase the reliability of their results.

Abstract The insulin therapy used to treat Diabetes Mellitus (DM) lacks educational tools to assist self-care. Thus, we aimed to develop and validate an educational tool for the relationship between glycemic variation and insulin therapy for adults with type 1 and 2 DM. The study was developed in three stages: i) elaboration of the educational tool; ii) validation of content and display by a panel of judges; iii) pre-test with a target audience. Ten judges participated in the second stage, and 12 insulin-dependent adults with type 1 or 2 DM participated in the third stage. The Content Validity Index (CVI) was used to evaluate the adequacy of the material by the judges. The percentages of the agreement by item were calculated for validation by the target audience. The My Treatment Diary (MTD) educational tool was then developed. It obtained a mean CVI of 99.6% and a percentage of agreement of 99%. The results demonstrated that the content and display of the MTD tool were validated and culturally appropriate for the population of adults with type 1 and 2 DM. (DM selfcare. selfcare self care. care self-care Thus stages i ii iii pretest pre test audience stage insulindependent dependent (CVI (MTD 996 99 6 99.6 99% 9 99.

Resumo A insulinoterapia empregada no tratamento do Diabetes Mellitus (DM) carece de ferramentas educativas que auxiliem a prática de autocuidado. Dessa forma, objetivou-se elaborar e validar uma ferramenta educativa destinada a promover a compreensão da relação entre variação glicêmica e insulinoterapia em adultos com DM1 e DM2. Trata-se de um estudo metodológico desenvolvido em três etapas: i) elaboração da ferramenta educativa; ii) validação de conteúdo e aparência por comitê de juízes; iii) pré-teste com o público-alvo. Participaram da segunda etapa dez juízes e da terceira etapa 12 adultos com DM 1 ou 2, em uso de insulina. Para avaliar a adequação do material educativo pelo comitê de juízes foi utilizado o Índice de Validade de Conteúdo (IVC). Para validação pelo público-alvo foram calculados os percentuais de concordância por itens. Como resultado, desenvolveu-se a ferramenta educativa Meu Diário de Tratamento (MDT), que obteve IVC médio de 99,6% e percentual de concordância de 99%. Conclui-se, portanto, que o conteúdo e a aparência da ferramenta MDT foram validados e adequados culturalmente para a população de adultos com DM tipo 1 e 2. (DM autocuidado forma objetivouse objetivou se DM2 Tratase Trata etapas i ii iii préteste pré teste públicoalvo. públicoalvo público alvo. alvo 2 insulina IVC. . (IVC) itens resultado desenvolveuse desenvolveu MDT, , (MDT) 996 99 6 99,6 99% Concluise, Concluise Conclui se, Conclui-se portanto (IVC (MDT 9 99,