The inhibition of the fatty acid amide hydrolase (FAAH), an endocannabinoid system component, emerged as a potentially new therapeutic target for a range of clinical disorders such as acute and chronic pain. Some α-ketoheterocycle derivatives demonstrated interesting analgesic and anti-inflammatory activities in vitro. Ligand-Based Drug Design techniques such as knowledge graph convolutional networks (kGCN) and hologram quantitative structure-activity relationship (HQSAR) using α-ketoheterocycle derivatives from five different datasets were generated to discover the relation between the chemical structures and the inhibition activity. Meanwhile, structure-based drug design simulations as interaction fields (MIF), molecular docking, and ligand sites studies (LSI) from FAAH were performed using Autogrid software and FTmap/FTsite servers. The results of both studies were merged to propose predictive models. The resulting kGCN model demonstrated adequate accuracy area under the curve by receiver operating characteristic (AUC-ROC 0.7922). From contribution maps of the Ligand-Based Drug Design (LBDD) models and the generated probes using MIF and LSI, it was observed that the oxazole ring, the ketone group, and the apolar chain present in the structures of the inhibitors are important, besides the evidence of the Cys269 and Val270 residues importance for the potential interaction, confirmed by carried docking studies. These fragments and structural information can be used to carry out new FAAH potential inhibitors studies and report kGCN as an accurate classification technique. FAAH, , (FAAH) component pain αketoheterocycle α ketoheterocycle antiinflammatory anti inflammatory vitro LigandBased Ligand Based (kGCN structureactivity structure activity HQSAR (HQSAR Meanwhile structurebased based MIF, (MIF) LSI (LSI FTmapFTsite FTmap FTsite servers AUCROC AUC ROC 0.7922. 07922 0.7922 . 0 7922 0.7922) LBDD (LBDD ring group important Cys Cys26 Val Val27 technique (FAAH (MIF 0792 0.792 792 Cys2 Val2 079 0.79 79 07 0.7 7 0.

ABSTRACT Purpose: This study aimed to analyze variations in intraoperative corneal thickness during corneal cross-linking in patients with keratoconus and to investigate its possible correlation with presurgical maximal keratometry (Kmax) and pachymetry. Methods: This was a prospective case series. We used a method similar to the Dresden protocol, with the application of hydroxypropyl methylcellulose 0.1% hypo-osmolar riboflavin in corneas between 330 and 400 µm after epithelium removal. Corneal thickness was measured using portable calipers before and immediately after epithelium removal, and 30 and 60 min after the procedure. Results: The 30 patients in this study were followed up for one year. A statistically significant difference was observed in pachymetry values during the intraoperative period (p<0.0001) and an increase of 3.05 µm (95%C1: 0.56-5.54) for each diopter was seen after epithelium removal (p0.019). We found an average Kmax difference of —2.12 D between men and women (p0.013). One year after treatment, there was a statistically significant reduction in pachymetry (p<0.0001) and Kmax (p0.0170) values. Conclusions: A significant increase in pachymetry measurements was seen during the procedure, and most patients showed a regression in Kmax and pachymetry values one year after surgery. Purpose crosslinking cross linking (Kmax Methods series protocol 01 0 1 0.1 hypoosmolar hypo osmolar 33 40 3 6 procedure Results p<0.0001 p00001 p 0001 (p<0.0001 305 05 3.0 95%C1 95C1 C 95 C1 (95%C1 0.565.54 056554 0.56 5.54 56 5 54 0.56-5.54 p0.019. p0019 p0.019 . p0 019 (p0.019) 2.12 212 2 12 —2.1 p0.013. p0013 p0.013 013 (p0.013) treatment p0.0170 p00170 0170 (p0.0170 Conclusions surgery 0. 4 p<0.000 p0000 000 (p<0.000 3. 95%C 95C 9 (95%C 565 0.565.5 05655 056 0.5 554 5.5 0.56-5.5 p001 p0.01 (p0.019 2.1 21 —2. (p0.013 p0.017 p0017 017 (p0.017 p<0.00 p000 00 (p<0.00 0.565. 0565 55 5. 0.56-5. p00 p0.0 (p0.01 2. —2 p<0.0 (p<0.0 0.565 0.56-5 p0. (p0.0 — p<0. (p<0. 0.56- (p0. p<0 (p<0 (p0 p< (p< (p

ABSTRACT Mantle cell lymphoma of the ocular and periorbital regions is extremely rare but should be considered in the differential diagnosis of lesions affecting the periorbital tissues. In this study, we present a rare case of mantle cell lymphoma of the lacrimal sac in a 65-year-old male presenting with a mass in the lacrimal sac region and epiphora. After clinical examinations and imaging studies, the mucocele was misdiagnosed. Considering the unexpected findings during external dacryocystorhinostomy, a frozen biopsy was performed, which confirmed the diagnosis of lymphoma. tissues study 65yearold yearold 65 year old epiphora studies misdiagnosed dacryocystorhinostomy performed 6

RESUMO Objetivo: Identificar e caracterizar a população de casos pediátricos encaminhados para o nosso centro de oxigenoterapia hiperbárica. Métodos: Estudo retrospetivo e observacional, que incluiu doentes pediátricos tratados com oxigenoterapia hiperbárica, de 2006 a 2021, no centro de referência de medicina hiperbárica do norte de Portugal. As variáveis de interesse foram extraídas dos processos clínicos eletrônicos. Resultados: O nosso estudo incluiu 134 casos. Os motivos de encaminhamento mais frequentes foram intoxicação por monóxido de carbono (n=59) e surdez súbita neurossensorial (n=41). Em 75 casos (56%) o tratamento foi iniciado em contexto de urgência. Os sintomas de apresentação à admissão variaram entre os diferentes casos, sendo os mais frequentes cefaleias e náuseas/vômitos. No que diz respeito à intoxicação por monóxido de carbono, as fontes mais comuns foram o aquecedor, lareira/braseiro e caldeira. Com relação aos efeitos adversos, foram identificados um caso de intoxicação por oxigênio e quatro casos de barotrauma do ouvido médio. Conclusões: A causa mais frequente de encaminhamento foi a intoxicação por monóxido de carbono. Todos os pacientes evoluíram favoravelmente e foram registrados poucos efeitos adversos, o que enfatiza a segurança desta terapia. Uma vez que a maioria dos pediatras pode não estar informada sobre os potenciais benefícios da oxigenoterapia hiperbárica, é de extrema importância promovê-los para que esta técnica seja cada vez mais implementada. Objetivo Métodos observacional 200 2021 Portugal eletrônicos Resultados 13 n=59 n59 n 59 (n=59 n=41. n41 n=41 . 41 (n=41) 7 56% 56 (56% urgência náuseasvômitos náuseas vômitos náuseas/vômitos aquecedor lareirabraseiro lareira braseiro caldeira adversos médio Conclusões terapia promovêlos promovê los implementada 20 202 1 n=5 n5 5 (n=5 n4 n=4 4 (n=41 (56 2 n= (n= (n=4 (5 (n (

ABSTRACT Objective: To identify and characterize the population of Pediatric patients referred to our hyperbaric oxygen therapy center. Methods: Retrospective and observational study, including pediatric patients treated with hyperbaric oxygen therapy, from 2006 to 2021, at the hyperbaric medicine reference center in the north of Portugal. Variables of interest were extracted from electronic medical records. Results: Our study included 134 patients. The most frequent reasons for referral were carbon monoxide poisoning (n=59) and sudden sensorineural hearing loss (n=41). In 75 cases (56%), treatment was initiated in an urgent context. Symptom presentation at Emergency Department varied among patients, the most frequent being headache and nausea/vomiting. Concerning carbon monoxide poisoning, the most common sources were water heater, fireplace/brazier, and boiler. Regarding adverse effects, it was identified one case of intoxication by oxygen and four cases of middle ear barotrauma. Conclusions: The most frequent cause for referral was carbon monoxide poisoning. All patients evolved favorably, with few side effects being reported, emphasizing the safety of this therapy. While most pediatricians may not be aware of the potential benefits arising with hyperbaric oxygen therapy, it is of upmost importance to promote them, so that this technique is increasingly implemented. Objective Methods 200 2021 Portugal records Results 13 n=59 n59 n 59 (n=59 n=41. n41 n=41 . 41 (n=41) 7 56%, 56 56% , (56%) context nauseavomiting nausea vomiting nausea/vomiting heater fireplacebrazier fireplace brazier fireplace/brazier boiler barotrauma Conclusions favorably reported them implemented 20 202 1 n=5 n5 5 (n=5 n4 n=4 4 (n=41 (56% 2 n= (n= (n=4 (56 (n (5 (

RESUMO Objetivo: O objetivo deste estudo foi realizar a correlação genótipo-fenótipo entre os resultados de cariótipos e as alterações neurológicas e psiquiátricas apresentadas em pacientes com síndrome de Turner (ST). Métodos: Um estudo retrospectivo foi conduzido nos registros médicos de 10/140 pacientes com ST e deficiências neuropsicológicas atendidos pelo Serviço de Genética Clínica de um hospital do sul do Brasil. Ademais, uma revisão foi realizada pelas plataformas científicas PubMed e Biblioteca Virtual em Saúde (BVS) de artigos publicados entre 1o de janeiro de 2012 e 1o de janeiro de 2023. Foram selecionados 14 artigos em uma análise em duas etapas. Resultados: Nossa pesquisa mostrou potencial correlação entre alterações neurológicas e psiquiátricas em pacientes com ST. Esses achados corroboram os descritos por outros autores — como a elevada prevalência de dificuldades de aprendizagem ou intelectuais. Entretanto, nossa amostra encontrou mais episódios convulsivos do que os descritos em outros estudos. Conclusões: A correlação estabelecida pode ser devida ao efeito dose-dependente do cromossomo X, visto que nossa revisão sugere que o número de cromossomos sexuais ou o desenvolvimento hormonal está associado a habilidades ou deficiências verbais, sociais e cognitivas. Objetivo genótipofenótipo genótipo fenótipo . (ST) Métodos 10140 10 140 10/14 Brasil Ademais BVS (BVS 201 2023 1 etapas Resultados intelectuais Entretanto estudos Conclusões dosedependente dose dependente X verbais cognitivas (ST 1014 10/1 20 202 101 10/ 2

ABSTRACT Objective: The objective of this study was to establish the genotype-phenotype correlation between karyotype results and the neurological and psychiatric alterations presented in patients with Turner syndrome (TS). Methods: A retrospective study was conducted on the medical records of 10/140 patients with TS and neurophysiological abnormalities seen at a university hospital in southern Brazil. In addition, a literature review spanning the period from January 1, 2012 to January 1, 2023 was carried out using the PubMed and Virtual Health Library databases. Results: Our study showed a potential correlation between neurological and psychiatric alterations in patients with TS. These findings are in accordance with those described in literature such as a high prevalence of learning or intellectual disabilities. However, our sample found more seizure episodes than those reported in other studies. Conclusions: The correlation established could be due to X chromosome dose–effect, as the review suggests that sex chromosome number and hormonal development can be associated with verbal, social, and cognitive skills or impairments. Objective genotypephenotype genotype phenotype . (TS) Methods 10140 10 140 10/14 Brazil addition 1 201 202 databases Results disabilities However studies Conclusions doseeffect dose effect dose–effect verbal social impairments (TS 1014 14 10/1 20 101 10/ 2

RESUMO Objetivo: Comparar a presença de anticorpos neutralizantes contra o SARS-CoV-2 no leite materno e no sangue das lactantes vacinadas em relação àquelas não vacinadas. Fontes de dados: Foi efetuado registro no International Prospective Register of Systematic Reviews — PROSPERO (CRD42021287554) e foram seguidas as diretrizes do Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA). Foram elegíveis estudos de coorte, caso-controle e transversais que avaliaram anticorpos contra o SARS-CoV-2 no leite e no sangue de lactantes vacinadas e tiveram como grupo controle lactantes não vacinadas. Utilizaram-se os Descritores em Ciências da Saúde (DeCs), Medical Subject Heading (MeSH) e Emtree para as bases Biblioteca Virtual em Saúde (BVS), Medical Literature Analysis and Retrieval System Online (Medline/PubMed) e Embase, respectivamente. Na Web of Science e Scopus foi feita adaptação da estratégia. Não foram estabelecid as restrições quanto ao período de publicação e idioma. Síntese dos dados: As buscas identificaram 233 registros. Foram excluídos 128 duplicados e 101 fora dos critérios de inclusão, e quatro estudos de coorte foram elegíveis. As lactantes vacinadas com Pfizer-BioNTech e Moderna apresentaram anticorpos contra SARS-CoV-2 no sangue e no leite materno. Conclusões: As mulheres lactantes vacinadas apresentaram níveis mais elevados de imunoglobulina G (IgG) e A (IgA) no soro e no leite materno em comparação com as mulheres não vacinadas. Objetivo SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- dados CRD42021287554 CRD (CRD42021287554 MetaAnalysis Meta PRISMA. PRISMA . (PRISMA) casocontrole caso Utilizaramse Utilizaram se DeCs, DeCs , (DeCs) MeSH (MeSH BVS, BVS (BVS) Medline/PubMed MedlinePubMed Medline PubMed (Medline/PubMed Embase respectivamente estratégia idioma 23 registros 12 10 inclusão PfizerBioNTech Pfizer BioNTech Conclusões IgG (IgG IgA (IgA SARS-CoV CRD4202128755 (CRD4202128755 (PRISMA (DeCs (BVS 1 CRD420212875 (CRD420212875 CRD42021287 (CRD42021287 CRD4202128 (CRD4202128 CRD420212 (CRD420212 CRD42021 (CRD42021 CRD4202 (CRD4202 CRD420 (CRD420 CRD42 (CRD42 CRD4 (CRD4 (CRD

ABSTRACT Objective: To compare the presence of neutralizing antibodies against SARS-CoV-2 found in the breast milk and blood of vaccinated lactating women with those not vaccinated. Data source: The study was registered in the International Prospective Register of Systematic Reviews (PROSPERO) under CRD42021287554 and followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Cohort, case-control, and cross-sectional studies that evaluated antibodies against SARS-CoV-2 in the milk and blood of vaccinated mothers and had as control group unvaccinated mothers were eligible. Health Sciences Descriptors (DeCs), Medical Subject Headings (MeSH) and Emtree descriptors were used for the Virtual Health Library (VHL), Medical Literature Analysis and Retrieval System Online (Medline/Pubmed), and Embase databases, respectively. In the Web of Science and Scopus, the strategy was adapted. No restrictions on the publication period and language were set. Data synthesis: The search identified 233 records, of which 128 duplicates and 101 papers that did not meet the inclusion criteria were excluded. Hence, four cohort studies were eligible. Nursing mothers vaccinated with the Pfizer-BioNTech and Moderna vaccines showed antibodies against SARS-CoV-2 in their blood and breast milk. Conclusions: Vaccinated lactating women had higher levels of immunoglobulin G (IgG) and A (IgA) in serum and breast milk than unvaccinated women. Objective SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- source PROSPERO (PROSPERO CRD CRD4202128755 MetaAnalyses Meta Analyses PRISMA (PRISMA guidelines Cohort casecontrol, casecontrol case control, case-control crosssectional cross sectional eligible DeCs, DeCs , (DeCs) MeSH (MeSH VHL, VHL (VHL) Medline/Pubmed, MedlinePubmed Medline/Pubmed Medline Pubmed (Medline/Pubmed) databases respectively Scopus adapted set synthesis 23 records 12 10 excluded Hence PfizerBioNTech Pfizer BioNTech Conclusions IgG (IgG IgA (IgA SARS-CoV CRD420212875 (DeCs (VHL (Medline/Pubmed 1 CRD42021287 CRD4202128 CRD420212 CRD42021 CRD4202 CRD420 CRD42 CRD4

Serial numbers are marks present on several day-to-day objects, created by manufacturers for purposes such as quality control, product tracking and to prevent counterfeiting. In the case of firearms, these characters can be obliterated or damaged by natural processes or intentionally by criminals to prevent positive identification of stolen property. One non-destructive method employed by crime laboratories for the restoration of obliterated characters is the magnetic particle method. The present work aims to study the synthesis and application of waste-made magnetic nanoparticles in the recovery of adulterated markings. A set of analytical-grade materials and metallic waste magnetic nanoparticles were synthesized for comparison purposes. Chemical characterization tests by X-ray fluorescence, morphological tests by scanning electron microscopy (SEM), and magnetization tests by vibrating sample magnetometer (VSM) were performed. The efficacy of the synthesized nanoparticles was tested on 1020 steel plates previously engraved and adulterated by sanding. Both homemade magnetic nanoparticles demonstrated superior performance compared to commercial magnetic particles. The application of homemade magnetic particles, especially using waste as the source of production, decreases the cost of the material and is environmentally friendly. The development of this material makes magnetic serial number restoration a better option for widespread use in forensic procedures. daytoday day objects control counterfeiting firearms property nondestructive non destructive wastemade made markings analyticalgrade analytical grade Xray X ray fluorescence SEM, SEM , (SEM) VSM (VSM performed 102 sanding particles production friendly procedures (SEM 10 1

RESUMO A aplicação de esgoto sanitário utilizando o gotejamento subsuperficial contribui para mitigar os problemas atuais de disponibilidade de água e produção de alimento. Objetivou-se avaliar o feijão-caupi recebendo esgoto sanitário por gotejadores operando com diferentes vazões e profundidades. Os gotejadores operaram com as vazões de 1,6 e 3,8 L h-1 e foram instalados nas profundidades de 0, 5, 10, 15, 20, 25 e 30 cm. O feijão-caupi foi cultivado em vasos de 65 L preenchidos com solo argiloso em casa de vegetação. Utilizou-se esgoto sanitário sintético e a quantidade aplicada nos vasos foi baseada no elemento limitante, que no caso foi o nitrogênio, para o cultivo do feijão-caupi. O manejo da irrigação foi realizado com sondas de TDR. Avaliou-se a germinação e as respostas fisiológicas e morfologia das raízes do feijão-caupi. A ascensão capilar, quando a água foi aplicada em profundidade, não foi suficiente para umedecer de maneira uniforme a superfície do solo. As variáveis de germinação apresentaram um decréscimo em função do aumento das profundidades de instalação dos gotejadores. A distribuição da água com o aumento da profundidade dos emissores foi responsável pelos prejuízos nas respostas fisiológicas e morfológicas das raízes feijão-caupi. As vazões dos gotejadores não afetaram a germinação do feijão-caupi. Utilizar o sistema de irrigação por gotejamento subsuperficial não foi apropriado para o feijão-caupi nas condições deste estudo. alimento Objetivouse Objetivou se feijãocaupi feijão caupi 16 1 6 1, 38 3 8 3, h1 h h- 0 5 10 15 20 2 cm vegetação Utilizouse Utilizou limitante nitrogênio feijãocaupi. caupi. TDR Avaliouse Avaliou capilar estudo

ABSTRACT The application of sanitary sewage using subsurface drip irrigation contributes to mitigating the current problems of water availability and food production. The aim in this study was to evaluate cowpea receiving sanitary sewage through drippers operating at different flow rates and depths. The drippers operated at flow rates of 1.6 and 3.8 L h-1 and were installed at depths of 0, 5, 10, 15, 20, 25, and 30 cm. Cowpea was grown in 65 L pots filled with sandy clay soil in a greenhouse. Synthetic sanitary sewage was used and the amount applied to the pots was based on the limiting element, which in this case was nitrogen, for growing cowpea. Irrigation was managed using TDR probes. Germination and the physiological responses and morphology of cowpea roots were assessed. Capillary rise, when water was applied in subsurface, was not sufficient to evenly moisten the soil surface. The germination variables decreased as a result of the increase in drip installation depths. The distribution of water as the depth of the emitters increased was responsible for the damage to the physiological and morphological responses of cowpea roots. The flow rates of the drippers did not affect the germination of cowpea. Using the subsurface drip irrigation system was not appropriate for growing cowpea under the conditions of this study. production 16 1 6 1. 38 3 8 3. h1 h h- 0 5 10 15 20 25 cm greenhouse element nitrogen probes assessed rise surface 2

RESUMO Objetivo: Descrever as etapas de um protocolo de decanulação e os resultados da aplicação desse protocolo em crianças hospitalizadas. Métodos: Trata-se de um estudo observacional retrospectivo. Os dados foram coletados de prontuários de pacientes decanulados acompanhados em um hospital pediátrico de Belo Horizonte, Minas Gerais, entre 2011 e 2021. Resultados: Foram analisadas 120 crianças com idade entre dois meses e 16 anos, com média de idade de quatro anos, 69% das quais eram do sexo masculino. Cerca de 75% dos pacientes apresentam traqueostomia por obstrução de vias aéreas superiores e 60% destes por estenose subglótica adquirida. No início do protocolo de decanulação, 5,5% dos pacientes apresentavam disfagia orofaríngea moderada, enquanto 80,4% apresentavam deglutição normal. A correção da pré-decanulação das vias aéreas superiores foi realizada em 39,5% dos pacientes, a dilatação em 63,8% e a correção endoscópica em 55,3%. Após a realização da decanulação, nenhum paciente apresentou complicações. Conclusões: O protocolo de decanulação descrito é seguro, pois a taxa de complicações como óbito e a necessidade de recanulação foi ausente. Objetivo hospitalizadas Métodos Tratase Trata se retrospectivo Horizonte Gerais 201 2021 Resultados 12 1 anos 69 masculino 75 60 adquirida 55 5 5,5 moderada 804 80 4 80,4 normal prédecanulação pré 395 39 39,5 638 63 8 63,8 553 3 55,3% Conclusões seguro ausente 20 202 6 7 5, 80, 39, 63, 55,3 2 55,

ABSTRACT Objective: The aim of this study was to describe the phases of a decannulation protocol and the results from its application in hospitalized children. Methods: This is a retrospective, observational study. Data were collected from medical records of decannulated patients followed up in a pediatric hospital in Belo Horizonte, Minas Gerais between 2011 and 2021. Results: Among the children followed up in the service (n=526), 23% (n=120) were successfully decannulated. Children aged between 2 months and 16 years, with a mean age of 4 years, 69% of whom were male, were evaluated. About 75% of the patients have tracheostomy due to upper airway obstruction and 60% of these due to acquired subglottic stenosis. At the beginning of the decannulation protocol, 5.5% of the patients had moderate oropharyngeal dysphagia, while 80.4% had normal swallowing. Correction in the upper airway pre-decannulation was performed in 39.5% of the patients, dilation in 63.8%, and endoscopic correction was performed in 55.3%. After performing the decannulation, none of the patients had complications. Conclusions: The described decannulation protocol is safe, since no complications such as death and need for recannulation happened. Objective Methods retrospective Horizonte 201 2021 Results n=526, n526 n n=526 , 526 (n=526) 23 n=120 n120 120 (n=120 1 years 69 male evaluated 75 60 stenosis 55 5 5.5 dysphagia 804 80 80.4 swallowing predecannulation pre 395 39 39.5 638 63 8 63.8% 553 3 55.3% Conclusions safe happened 20 202 n52 n=52 52 (n=526 n=12 n12 12 (n=12 6 7 5. 80. 39. 63.8 55.3 n5 n=5 (n=52 n=1 n1 (n=1 63. 55. n= (n=5 (n= (n

ABSTRACT Purpose: This study aimed to evaluate the morphometric and volumetric dimensions of the lacrimal gland in patients with inactive thyroid eye disease and compare them with the values reported in the literature. Methods: This case series evaluated consecutive patients with inactive thyroid eye disease treated at a tertiary eye hospital from 2015 to 2020. The patients’ baseline demographics and clinical characteristics were obtained. The axial and coronal length, width, and volume of the lacrimal gland were measured on computed tomography scan images, and the results were statistically analyzed. Results: A total of 21 patients (42 orbits) with inactive thyroid eye disease were evaluated. Their mean age was 49.0 ± 14.6 years, and 12 (57.1%) of them were men. The main complaint was dryness, and the majority of the patients had good vision and mild proptosis. The mean axial length and width of the lacrimal gland were 19.3 ± 3.9 mm and 7.5 ± 2.1 mm, respectively; coronal length and width, 20.4 ± 4.5 mm and 7.5 ± 2.1 mm, respectively; and lacrimal gland volume, 0.825 ± 0.326 mm3. Age, sex, or laterality were not found to be determinants of lacrimal gland enlargement. Conclusion: Patients with thyroid eye disease have enlarged lacrimal gland even in the nonactive phase of the disease multifactorial aspects influence the lacrimal gland in thyroid eye disease, making it difficult to establish a clear correlation with predisposing factors. Further studies are warranted to better understand the association between thyroid eye disease and the lacrimal gland. Purpose literature Methods 201 2020 obtained images analyzed Results 2 42 (4 orbits 490 49 0 49. 146 14 6 14. years 1 57.1% 571 57 (57.1% men dryness proptosis 193 19 3 19. 39 9 3. 75 7 5 7. 2. respectively 204 20 4 20. 45 4. 0825 825 0.82 0326 326 0.32 mm3 Age sex enlargement Conclusion factors 202 ( 57.1 (57.1 082 82 0.8 032 32 0.3 57. (57. 08 8 0. 03 (57 (5

Abstract The influence of occupant behaviour in buildings is widely discussed as one of the causes for the gap between energy use estimated via computer simulation and during building operation. Knowing the main drivers for adjustments in building systems is essential to guide the development of mathematical models for such behaviours. The aim of this study is to evaluate the main motivating agents for adjusting windows, luminaires, and air-conditioning in offices. Two offices were monitored using sensors that collected data from the internal environment and user interaction with such systems. Rainfall and external and internal air temperatures were considered influential for the interaction with window systems. The increase in internal and external temperatures had even more influence on interactions with air-conditioners. The main conclusions were: there is influence of the layout of the offices in the sharing and control of windows and efficiency of passive strategies, such as the use of natural and cross ventilation; and there is an influence of the increase in internal temperature compared to external temperature in the predictability of opening windows and turning air-conditioning devices on. operation behaviours luminaires airconditioning conditioning airconditioners. airconditioners conditioners. conditioners air-conditioners strategies ventilation

Resumo Ainfluência do comportamento dos usuários em edificações é amplamente discutida como uma das causas para discrepâncias entre consumos energéticos esperados, durante a fase de projeto, e consumos durante a operação. Conhecer os principais motivadores para ajustes nos sistemas de edificações é imprescindível para aprimorar a modelagem desses comportamentos. O objetivo deste estudo é avaliar os principais agentes motivadores para o ajuste das janelas, luminárias e aparelhos de ar-condicionado em escritórios. Dois escritórios foram monitorados por meio de sensores que coletaram dados de qualidade do ambiente interno e comportamento de usuário. Foram consideradas influentes para a interação com sistemas de janelas a pluviometria e as temperaturas do ar externo e interno. O aumento das temperaturas interna e externa apresentou ainda mais influência na interaçãocom aparelhos de ar-condicionado. Duas foram as principais conclusões: há influência do layout dos escritórios no compartilhamento e controle das janelas e eficiência de estratégias passivas, como o uso de ventilação natural e cruzada; e há influência do aumento da temperatura interna em comparação à externa na previsibilidade de abertura de janelas e acionamento de aparelhos de ar-condicionado. esperados projeto operação comportamentos arcondicionado condicionado usuário arcondicionado. condicionado. conclusões passivas cruzada

Abstract Only within the last decade, the works of Uruguay an Engineer Eladio Dieste (1917-2000) have been gaining international academic dissemination, one of whose main contributions in the realm of formal-structural conception within architecture and civil engineering reside in the iterative development of the structural typology of the gaussian vault shells in reinforced brickwork. However, there is not an established definition for this typology’s architectural geometry. Also, there is hardly any evidence of how such shells were designed. Therefore, the main objective, of this paper is to demonstrate the underlying geometric relationships in the discontinuous gaussian vault shells designed and built by Eladio Dieste in reinforced brickwork, the dominant typological variation within the object of study. This analysis was carried out by means of the parametric modeling and the polynomial regression of selected case studies from the primary sources, since such computational tools allow for the proper geometrical management of formally complex geometries. The expected contributions of this study reside in the deepening of the understanding of the relationship between the design process and the geometry of the object of study, as well as the understanding of the geometrical conformation of the structural typology conceived by Eladio Dieste. decade 19172000 1917 2000 (1917-2000 dissemination formalstructural formal brickwork However typologys s Also Therefore objective sources geometries 1917200 191 200 (1917-200 191720 19 20 (1917-20 19172 1 2 (1917-2 (1917- (1917 (191 (19 (1 (

Resumo Apenas na última década, a obra do engenheiro Uruguaio Eladio Dieste (1917-2000) vem ganhando disseminação acadêmica internacional, sendo que uma de suas principais contribuições para a concepção formal-estrutural na arquitetura e engenharia civil foi o desenvolvimento iterativo da tipologia estrutural das abóbadas gaussianas, cascas de dupla-curvatura estruturadas em cerâmica armada. Entretanto, não há registros de uma definição estabelecida para a geometria arquitetônica destas tipologias estruturais. Tampouco existem evidências concretas acerca da concepção e desenvolvimento projetual destas estruturas. Por conseguinte, o objetivo deste artigo é evidenciar as relações geométricas subjacentes nas abóbadas guassianas descontínuas projetadas e construídas por Eladio Dieste em cerâmica armada, a variação dominante desta tipologia estrutural. Esta análise foi conduzida através da modelagem paramétrica e da regressão polinomial de estudos de caso selecionados a partir de fontes primárias originais, justamente por estas ferramentas computacionais permitirem o correto manejo de geometrias tidas como formalmente complexas. A contribuição esperada para esta pesquisa reside em aprofundar o entendimento entre a relação do processo de projeto e a geometria resultante no objeto de estudo, assim como o entendimento da conformação geométrica desta tipologia estrutural desenvolvida por Eladio Dieste. década 19172000 1917 2000 (1917-2000 internacional formalestrutural formal gaussianas duplacurvatura dupla curvatura armada Entretanto estruturais estruturas conseguinte originais complexas estudo 1917200 191 200 (1917-200 191720 19 20 (1917-20 19172 1 2 (1917-2 (1917- (1917 (191 (19 (1 (

Abstract The identification of anomalies for damage mapping is a complex task that depends on knowledge of their manifestation. The purpose of this study is to propose criteria for detecting anomalies in mortar coatings by analyzing facade images, aiming to improve damage mapping. Specific parameters related to position (geometry), configuration, grouping, origin and nearby construction componentes are proposed to guide the identification of each damage, indicating what is most important to observe in each case. To apply the proposed method, six sections of building facades in Brasília - DF are selected. The main characteristics that aid in identifying the typology of each anomaly are obtained, and the applied methodology validates the proposed approach. The results show that the established criteria lead to precise anomaly identification, making the damage mapping process more efficient and reliable, contributing to the study of degradation. manifestation images geometry, geometry , (geometry) configuration grouping case method selected obtained approach reliable degradation (geometry

Resumo A identificação de anomalias para a elaboração de mapas de danos é uma tarefa complexa e depende do conhecimento das suas formas de manifestação. O objetivo deste estudo é propor critérios para a detecção de anomalias em revestimentos de argamassa, pela análise de imagens de fachadas, visando aperfeiçoar o mapeamento de danos. São propostos parâmetros específicos, relacionados a posição (geometria), configuração, agrupamento, origem e componentes construtivos próximos que direcionam para a identificação de cada dano, indicando o que é mais importante observar em cada caso. Para a aplicação do método proposto, são selecionados seis trechos de fachadas de edifícios de Brasília - DF. São obtidas as principais características que auxiliam na identificação da tipologia de cada anomalia e a aplicação realizada permite validar a abordagem proposta. Com os resultados alcançados, observa-se que os critérios estabelecidos conduzem para a identificação precisa das anomalias, tornando o processo de elaboração de mapas de danos mais eficiente e confiável, contribuindo para o estudo da degradação. manifestação argamassa específicos geometria, geometria , (geometria) configuração agrupamento dano caso proposto DF proposta alcançados observase observa se confiável degradação (geometria

Abstract Construction projects are highly complex systems that recurrently present discrepancies between work-as-imagined and work-as-done. Digital technologies, such as photogrammetry using UAVs (drones), are promising support tools to cope with this problem. Therefore, this study aims to evaluate the procedures for developing and assessing the quality of a 3D model generated through photogrammetry from images captured by a drone, comparing it to the as-designed BIM model. Thus, a case study was carried out in a residential low-income housing construction project in Camaçari, Brazil. Compared to the as-designed BIM 3D model, the photogrammetric model presented an average dimensional deviation of -1.68%. The model also presented issues such as occlusions and deformations. The study highlights that both this deviation and the quality of the photogrammetric model can be significantly influenced by the data collection method (e.g., quantity and resolution of photos). The study's primary contribution lies in presenting the potential of UAV usage for image capture in photogrammetry model generation. workasimagined work imagined workasdone. workasdone done. done work-as-done technologies drones, drones , (drones) problem Therefore D drone asdesigned designed Thus lowincome low income Camaçari Brazil 1.68%. 168 1 68 -1.68% deformations e.g., eg e g (e.g. photos. photos . photos) studys s generation (drones 1.68% 16 6 -1.68 e.g. (e.g 1.68 -1.6 e.g 1.6 -1. 1. -1 -

Resumo Projetos de construção são sistemas altamente complexos que apresentam recorrentemente discrepâncias entre o trabalho planejado e o trabalho realizado. Tecnologias digitais, como a fotogrametria com VANTs (drones), são ferramentas de suporte promissoras nesse contexto. Assim, este estudo tem como objetivo avaliar os procedimentos de desenvolvimento e qualidade de um modelo 3D gerado por fotogrametria através de imagens capturadas por drone, comparando-o ao modelo as-designed BIM. Para isso, realizou-se um estudo de caso em uma habitação de interesse social localizada em Camaçari-BA. Comparado ao modelo BIM projetado, o modelo fotogramétrico apresentou um desvio dimensional médio de -1,68%. O modelo também apresentou inconsistências como oclusões e deformações. O estudo mostra que tanto esse desvio como a qualidade do modelo fotogramétrico obtido podem ser consideravelmente influenciados pela forma de coleta dos dados (ex. baixa quantidade e resolução das fotos). A principal contribuição do estudo é apresentar o potencial do uso do VANT para captura de imagens para geração de um modelo de fotogrametria. realizado digitais drones, drones , (drones) contexto Assim D drone comparandoo comparando asdesigned as designed isso realizouse realizou se CamaçariBA. CamaçariBA Camaçari BA. BA Camaçari-BA projetado 1,68%. 168 1 68 -1,68% deformações ex. ex (ex fotos. fotos . fotos) (drones 1,68% 16 6 -1,68 1,68 -1,6 1,6 -1, 1, -1 -

Resumo: Este artigo analisa o processo de integração em novos padrões de consumo de jovens assalariados rurais em um território da serra equatoriana, onde predominam os negócios agrícolas de flores e brócolis. O objetivo é mostrar as condições estruturais que permitem aos jovens assalariados adotarem novos habitus mais próximos do consumo de bens globais, um processo intimamente relacionado com a sua posição no campo social. Na primeira parte, analisamos a relação entre consumo e habitus nas zonas rurais a partir de diferentes perspectivas teóricas sociológicas. A segunda parte, baseada em um estudo de caso, trata das tendências de consumo entre a juventude rural. A terceira parte reflete sobre a importância de novos padrões de consumo entre os jovens assalariados através do acesso a dois tipos de mercadorias globais (motocicleta e celular) que se tornaram novos objetos simbólicos e de prestígio. Resumo equatoriana brócolis social sociológicas caso rural motocicleta celular prestígio

Abstract: This article analyzes the process of integration into new consumption patterns of young rural wage earners in a territory of the Ecuadorian highlands, where flower and broccoli agribusinesses predominate. We seek to show the structural conditions that allow young wage earners to adopt new habitus closer to the consumption of global goods, a process narrowly related to their position in the social field. In the first part, we analyze the relationship between consumption and habitus in rural areas from different sociological theoretical perspectives. In the second part, based on a case study, we address consumption trends among rural youth. The third part reflects on the importance of new consumption patterns among young wage earners through access to two types of global merchandise (motorcycle and cell phone) that have become new symbolic and prestige objects. Abstract highlands predominate goods field perspectives study youth motorcycle phone objects

Resumen: En este artículo se analiza el proceso de integración a nuevos patrones de consumo de los jóvenes asalariados rurales en un territorio de la sierra ecuatoriana, donde predominan los agronegocios de flores y brócoli. Se busca mostrar las condiciones estructurales que permiten a los jóvenes asalariados adoptar nuevos habitus más cercanos al consumo de mercancías globales, proceso estrechamente relacionado con su posición ocupada en el campo social. En una primera parte, analizamos la relación entre consumo y habitus en el medio rural desde distintas perspectivas teóricas sociológicas. En una segunda parte, a partir de un estudio de caso, se abordan las tendencias del consumo entre los jóvenes rurales. En una tercera parte se reflexiona sobre la importancia de nuevas pautas de consumo entre los jóvenes asalariados a través del acceso a dos tipos de mercancías globales (motocicleta y celular) que se han convertido en nuevos objetos simbólicos y de prestigio. Resumen ecuatoriana brócoli social sociológicas caso motocicleta celular prestigio