Resumen Objetivo: caracterizar sociodemográficamente pacientes que padecen trastornos del estado de ánimo en Institución Prestadora de Servicios (IPS) de salud mental en Montería, departamento de Córdoba - Colombia, correlacionando este diagnóstico con variables de interés. Materiales y métodos: estudio descriptivo, retrospectivo-longitudinal, que correlacionó variables sociodemográficas con trastornos del estado de ánimo en 729 pacientes hospitalizados en una IPS, procedentes de municipios del departamento de Córdoba, en el período 2012- 2021-I. Resultados: hombres con edad promedio de 23 años presentaron mayor frecuencia de trastornos del estado de ánimo n=689 que mujeres n= 40; en su mayoría procedentes de municipios como Montería, Puerto Libertador, Valencia, Tierralta y Canalete; siendo Montería el municipio con mayor población y menor prevalencia; factores como lugar de procedencia, falta de apoyo familiar y estrés fueron quienes incidieron en recaídas, registrándose disminución en hospitalización de estos pacientes durante la pandemia COVID-19. Conclusión: existe correlación entre variables sociodemográficas como lugar de procedencia del departamento de Córdoba, falta de apoyo familiar y estrés como determinantes para la ocurrencia del diagnóstico de trastornos del estado de ánimo, en pacientes que proceden de municipios caracterizados por niveles de violencia alto y medio, baja cobertura educativa y pobreza multifuncional en población vulnerable.

ABSTRACT Objective : To sociodemographically characterize patients with Mood Disorders in a Mental Health Institution in Montería, Córdoba - Colombia, and correlate this diagnosis with variables of interest. Materials and Methods: This descriptive, retrospective-longitudinal study correlated sociodemographic variables with Mood Disorders in 729 hospitalized patients in an Institution of Mental Health, originating from municipalities in the department of Córdoba, during the period 2012-2021. Results: Men with an average age of 23 years presented a higher frequency of Mood Disorders (n=689) compared to women (n=40). The majority of patients originated from municipalities such as Montería, Puerto Libertador, Valencia, Tierralta, and Canalete. Montería, being the municipality with the largest population, showed a lower prevalence. Factors such as place of origin, lack of family support, and stress influenced relapses, with a decrease in hospitalizations of these patients during the COVID-19 pandemic. Conclusion: There is a correlation between sociodemographic variables such as the place of origin in the department of Córdoba, lack of family support, and stress as determinants for the occurrence of Mood Disorders diagnosis in patients from municipalities characterized by high and medium levels of violence, low educational coverage, and multifunctional poverty in vulnerable populations.

Abstract Introduction/objective: In this cross-sectional study, the connections between indicators of subjective happiness, hope, and resilience were investigated in 591 adult Paraguayans (average age 37.7 years; SD = 11.35) during the COVID-19 post-pandemic period, using network analysis for the first time. Method: The indicators of subjective happiness, hope, and resilience were assessed using the Subjective Happiness Scale, the Adult Hope Scale, and the 10-item Connor-Davidson Resilience Scale, respectively. Result: The results indicated that “Enjoy life in spite of it all,” “Pursuing goals,” and “Coping with stress” were the most central indicators of the resilience, hope, and subjective happiness network. While stronger conditional relationships were observed between indicators of the same network variable, potential bridge indicators were also noted that could link resilience, hope, and subjective happiness, such as “I am a strong person,” “Enjoy life in spite of it all,” “Pursuing goals,” and “I have been successful in life.” Conclusions: The results suggest that timely and multilevel interventions targeted at central and bridge indicators can help promote positive emotions that impact mental health.

Resumen Introducción/objetivo: En este estudio transversal se investigaron las conexiones entre los indicadores de felicidad subjetiva, esperanza y resiliencia en 591 paraguayos adultos (edad promedio 37.7 años; DE = 11.35) en el período pospandemia del COVID-19 utilizando análisis de redes por primera vez. Método: Los indicadores de felicidad subjetiva, esperanza y resiliencia se evaluaron utilizando la Escala de Felicidad Subjetiva, la Escala de Esperanza del Adulto y la Escala de Resiliencia de Connor-Davidson de 10 ítems, respectivamente. Resultados: Los resultados indicaron que “Disfrutar la vida a pesar de todo”, “Perseguir metas” y “Afrontar el estrés” fueron los indicadores más centrales de la red de resiliencia, esperanza y felicidad subjetiva. Si bien se observaron relaciones condicionales más fuertes entre indicadores de la misma variable de red, también se observaron posibles indicadores puente que podrían vincular la resiliencia, la esperanza y la felicidad subjetiva, como “Soy una persona fuerte”, “Disfruta la vida a pesar de todo”, “Persiguiendo metas” y “He tenido éxito en la vida”. Conclusiones: Los resultados sugieren que las intervenciones oportunas y multinivel dirigidas a indicadores centrales y puente pueden ayudar a promover emociones positivas que impacten la salud mental.

SUMMARY OBJECTIVE: The objective of this study was to evaluate the fear, anxiety, and knowledge level in women who underwent gynecological surgical procedures during the COVID-19 pandemic. METHODS: This cross-sectional study was conducted on 188 women who underwent a gynecologic surgical operation in Muğla, Turkey. Data were collected by using demographics and obstetric detail form, questionnaire on knowledge, attitudes, and practice toward COVID-19, and State-Trait Anxiety Inventory-I (STAI-I). RESULTS: Most of the women perceived their surgical process as very urgent. Women felt fear mostly for being infected with the virus, and they were afraid of transmitting COVID-19 to another one. The COVID-19 knowledge scores of women who had undergone cancer surgery were statistically significantly higher than others (p=0.017). The STAI-I scores of women increased as their COVID-19 knowledge scores increased (p<0.05). CONCLUSION: This study demonstrated that women were afraid of COVID-19 infection during gynecological operation and due to hospitalization, sociodemographic characteristics affected the knowledge levels about COVID-19 infection, and the anxiety levels of the women. Planning appropriate interventions to decrease the fear and anxiety of women who undergo gynecological surgery during the pandemic is important to ensure that women adhere to their treatment and follow-up in the postoperative period. OBJECTIVE COVID19 COVID 19 COVID-1 METHODS crosssectional cross sectional 18 Muğla Turkey form attitudes COVID19, 19, StateTrait State Trait InventoryI Inventory I STAII. STAII STAI . (STAI-I) RESULTS urgent virus one p=0.017. p0017 p p=0.017 0 017 (p=0.017) p<0.05. p005 p<0.05 05 (p<0.05) CONCLUSION hospitalization followup follow up period COVID1 1 COVID- (STAI-I p001 p=0.01 01 (p=0.017 p00 p<0.0 (p<0.05 p=0.0 (p=0.01 p0 p<0. (p<0.0 p=0. (p=0.0 p<0 (p<0. p=0 (p=0. p< (p<0 p= (p=0 (p< (p= (p

This qualitative study employed a community-based participatory action research approach to explore adolescent mothers' lived experiences and meaning-making processes in a marginalised South African community. Amidst the challenges posed by the COVID-19 pandemic, we adapted our study's methodology by leveraging my skills as an intern educational psychologist and art teacher. With my supervisor's guidance, I created a safe and empowering virtual environment for our co-researchers to share their experiences and emotions, which allowed us to navigate the pandemic's unique constraints while maintaining our research's integrity. Using innovative arts-based methods, including river of life, clay modelling, photo collage, and photovoice activities, provided a powerful means for the co-researchers to express their stories, identities, and aspirations in diverse and nuanced ways. These creative interventions served as catalysts for self-reflection, collective meaning-making, and facing the challenge of societal stigma-fostering a sense of solidarity and empowerment among the co-researchers. The transformative potential of arts-based methods was amplified by the research's participatory ethos, which prioritised the voices and experiences of the co-researchers and sought to generate insights that could inform community-driven solutions. The virtual space became a platform for authentic dialogue, relationship building, and the co-creation of knowledge, underscoring the adaptability and resilience of participatory research in the face of global challenges. This study highlights the power of arts-based data generation methods and participatory approaches in generating rich, meaningful data and fostering transformative experiences for marginalised communities. It calls for further research and interventions that prioritise the voices and needs of adolescent mothers, ultimately promoting their well-being, resilience, and social change.

Die inflasiekoers en die produksiegaping speel 'n belangrike rol in die monetêrebeleidstand-punt. Alhoewel die publiek inflasie redelik goed verstaan, is die produksiegaping 'n relatief onbekende begrip. Definisies van potensiële produksie kan dubbelsinnig wees, aangesien die term dikwels gebruik word om verwante, maar logies afsonderlike, konsepte te beskryf. Die produksiegaping word ook nie direk waargeneem nie en word afgelei uit beramings van potensiële produksie, wat self nie waarneembaar of meetbaar is nie en dus beraam moet word. Hierdie beramings kan egter sensitief wees vir verskillende metodologiese paradigmas en databeskikbaarheid. Die doel van hierdie artikel is om by te dra tot 'n beter begrip van en groter deursigtigheid in plaaslike monetêre beleid deur die rol van die produksiegaping in Suid-Afrikaanse monetêre beleid te verduidelik. Eerstens word die idees onderliggend aan die konsep van die produksiegaping bespreek, waarna 'n werksdefinisie van die produksiegaping in die konteks van monetêre beleid voorgestel word. Verskeie metodologieë en empiriese tegnieke waarvolgens potensiële produksie en die produksiegaping beraam kan word, word bespreek, insluitende eenveranderlike statistiese tegnieke, strukturele modelle en semistrukturele benaderings. Die artikel verduidelik voorts hoe die Suid-Afrikaanse Reserwebank (SARB) die plaaslike produksiegaping beraam en hoe hierdie beraamde produksiegaping op die monetêrebeleidstand-punt inwerk. Ten slotte word die SARB se monetêrebeleidstandpunt beskou met betrekking tot die inflasiekoers en produksiegapingsberamings oor die afgelope twee dekades ten einde die reaksie van die plaaslike monetêre beleid op groot ekonomiese skokke soos die wêreldwye finansiële krisis en COVID-19 te illustreer, en ten einde die beramings se sensitiwiteit vir datahersienings uit te lig.

The inflation rate and the output gap are two of the main determinants of the monetary policy stance. However, while inflation is relatively well understood by the public, the output gap is not. The output gap is not directly observed and is derived from estimates of potential output. Potential output is also not observable or measurable, and therefore needs to be estimated. Such estimates can, however, be sensitive to different methodological paradigms and the availability of data, while definitions of potential output may be ambiguous, because the term is often used to describe related, but logically distinct, concepts. With the aim of contributing to a better understanding of and greater transparency in domestic monetary policy, this paper describes the role of the output gap in South African monetary policy by broadly examining the following three questions: (i) What exactly is the output gap?; (ii) How is it measured? and (iii) Why is it important? To begin with, the idea underlying the concept of the output gap is explained and a tentative working definition of the output gap in the context of monetary policy is provided. Various methodologies and empirical techniques of estimating potential output and the output gap are then discussed, including univariate statistical techniques, structural models and semi-structural approaches. This is followed by an explanation of how the South African Reserve Bank (SARB) estimates the domestic output gap, and how the estimated output gap feeds into the monetary policy stance. Finally, the SARB's monetary policy stance is viewed in relation to the inflation rate and output gap estimates over the last two decades to illustrate the domestic monetary policy response to notable economic events such as the global financial crisis and the COVID-19 shock, and to highlight the sensitivity of the estimates to data revision. This paper shows that both actual and potential economic growth have declined over the last decade, even without taking into account the COVID-19 shock. This is consistent with the South African empirical literature, and points to a worrying and persistent stagnation in domestic economic activity. After strong economic activity during the early 2000s, the economy started slowing down in 2008. This may be ascribed to a number of factors, including the introduction of load-shedding in 2007, changes in the global economic landscape following the globalfinancial crisis, dwindling infrastructure investment after the 2010 FIFA World Cup tournament, and uncertainty about domestic economic policy. COVID-19 brought about a massive economic shock in 2020. Lockdown regulations saw capital and labour withdrawn from economic use, which caused real GDP and potential output to contract by 6,2% and 2,7%, respectively, for the year. The output gap, which has mainly remained in negative territory since 2009, fell to -7,9% in the second quarter of 2020. In response to the crisis, the SARB drastically lowered the policy rate and applied several other financial market interventions, but even this extensive range of stimuli failed to prevent an economic collapse. Moreover, the output gap has remained negative despite a minor rebound of the economy in 2021 and 2022, which indicated that economic activity remained on its weakpre-COVID-19 trajectory. Inflation has stabilised markedly since 2010. This may be partly due to weak domestic economic activity that does not exert significant domestic inflationary pressures. In fact, many of the notable inflationary episodes of the last 25years were largely caused by external factors, such as the rand depreciation shock and the global financial crisis. This benign domestic inflationary environment has arguably made it easier for the SARB to achieve its inflation target. Such consistency has contributed to an increase in the SARB's credibility, which, in turn, has led to inflation expectations that are lower and better anchored.

Hierdie sewe-jaar longitudinale opvoedingstudie evalueer drie akademiese afleweringsmodusse vir deeltydse MBA-studente in hul Bemarkingsbestuursmodule, naamlik vol kontak (20172019), vol aanlyn tydens COVID-19 se harde inperking (2020-2021 en die daaropvolgende gemengde modus (2022-2023). Die studie het ten doel om te bepaal of die afleweringsmodus studente se akademiese prestasie beduidend beïnvloed. Die eenrigting-variansie-analise (EVA) het beduidende verskille tussen die afleweringsmodusse vir individuele opdragte (normatiewe assessering) en groepgevallestudies (summatiewe assessering) geïdentifiseer. Daar was ook betekenisvolle verskille tussen die akademiese prestasie ten opsigte van die finale saamgestelde portefeulje van kennis (wat as eksamen dien). Hierdie portefeulje bestaan uit 'n prakties-toegepaste bemarkingsplan. Die post-hoc toetse het getoon dat studente aansienlik beter gevaar het tydens die gemengde afleweringsmodus in individuele opdragte, terwyl die volledige aanlyn modus laer punte vir die groepgevallestudies gehad het. Beide die gemengde en volledige kontakmodusse het beduidende opeenvolgende verbetering vir die groepgevallestudies getoon, wat in elke gevallestudie verbetering getoon het namate die semester gevorder het. Dit verskil van volledige aanlyn onderrig. Die gemengde modus het ook aansienlik beter gevaar in die eksamen- en finale modulepunte en het selfs beter gevaar as volkontakklasse.

The COVID-19 pandemic significantly transformed the tertiary education landscape. Traditional contact universities were forced abruptly to adopt a full-distance education mode, a situation neither the students nor lecturers were prepared for. Many lectures and teaching activities were developed on the fly as universities struggled to roll out the needed support in double-time for lecturers and students. This new normal for education required integrating technology, advanced communication software, revised assessment techniques, and recognising the need for flexible and adaptable approaches to teaching and learning. Students also evolved and gained technological proficiency, adaptability, time management, soft skills, social media proficiency, and an awareness of health and well-being. Albeit uncertain in redefining the new normal, universities continue to provide quality education. However, exactly how university education should be delivered to a new breed of students in a new business environment is a challenge. This is even more so in the case of executive MBA students. After the hard lockdown and restrictions were lifted on 21 September 2020, the North-West University Business School started to explore other modes of academic content delivery. Reinstating a full contact delivery mode was not an option because of remaining restrictions. High technological investment, online-educated lecturers and students, and benefits and developments during online learning now form a new normal for the Business School. Which teaching method, or rather, which mode of delivery, is the most relevant and adequate? Should the MBA lectures return to the historic full-contact delivery mode, stick with the newly established full online mode, or attempt to integrate the benefits of both into a hybrid mode of delivering business education to a new breed of technology-savvy students? This study, therefore, examines the academic performance of the different delivery modes by comparing data of Executive MBA Marketing management students at the NWU Business School in South Africa. The study examines the academic performance of these students from 2017 up to 2023. The panel database consists of Executive MBA students'marks for the module in Marketing Management from 2017 up to 2023. The database contains marks for individual assignments, groupwork case studies, final individual- and groupwork marks, exam marks and the final module mark. The final assessment is a portfolio of evidence comprising a detailed marketing plan for a product, service, or organisation of choice. The mode of delivery served as the dependent variable, while the independent variables comprised the marks for each assignment (groupwork, individual and portfolio of evidence). Three delivery modes were compared, namely full-contact (2017-2019), full-online (2020-2021), and the post-pandemic hybrid mode currently in effect (2022-2023). The data comprised 630 cases. However, the analysis of variance (ANOVA) used 532 cases to compare the different groupwork assignments (230 full-contact students, 159 full-online students, and 143 hybrid students). Cronbach's alpha coefficient measured the data's reliability, and one-way ANOVA determined significant differences (p<.05) between the academic performance of the three delivery modes. The analysis confirmed that significant differences exist between the modes of delivery for individual assignments, group case studies and exams (p<.05). The Tukey ab post-hoc tests showed that students performed significantly better during the hybrid delivery mode in individual assignments (69.2%) than full contact (63.8%). Regarding the individual assignment, the full online (63.8%) and full contact (63.7%) delivery modes perform significantly worse than the hybrid (69.2%) delivery mode. Regarding the first group case study (Group Assignment 1), full online performs (67.3%) significantly worse than hybrid (71.1%) and full contact (73.6%) delivery modes. There is no significant difference between the hybrid and full contact delivery modes. In the second, third, and fourth group case studies (Group Assignments 2, 3 & 4), the hybrid delivery mode (82.37%, 75.4%, 82.7%) outperforms the full contact (75.4, 80.1%, 86.6%) and full-online (71.4%, 71.4%, 67.8%) modes. The hybrid delivery mode, therefore, proves to be more conducive towards academic performance in group work. Finally, in considering the final module mark, the hybrid delivery mode (71.0%) is significantly higher than the other two delivery modes. However, there is no significant difference between full online (67.5%) and full-contact (67.2%) delivery modes regarding the final module mark. Nevertheless, it is noteworthy that the better performance in the final module marks is a function of the groupwork where the students analysed case studies together. There are no significant differences in the exam marks between the delivery modes, so better academic performance in the hybrid mode of delivery where groupwork is concerned culminates in the better module mark. Based on the findings, it is evident that the hybrid mode of delivery results in the best academic performance. This observation is based on three reasons, namely 1) students performed better in both the normative and summative assessments during hybrid tuition; 2) there is continuous progressive learning throughout the semester regarding the group case studies (summative assessment). They learn to improve and hone their skills to analyse better and apply business solutions to real-life problems experienced by organisations. This is based on students' improving marks in the group case studies as they become more proficient in analysing and answering the applied case studies because they learn from each case study; and 3) the students perform better academically in their normative assessments and earn higher final module marks (partially due to reason 2). It is concluded that the hybrid delivery mode facilitates the academic performance of post-pandemic executive MBA Marketing management students. JEL KODES: I23, I21, M30

Abstract Objective: This systematic review aims to clarify COVID-19’s impact on the onset of T2D in adults. Material and methods: Following PRISMA guidelines, this systematic review sourced data from multiple databases from 2019 to April 20th, 2023. Two reviewers handled screening, with a third-party resolving disagreement. The focus was on COVID-19 cases with post-infection T2D symptoms persisting for two or more months. Exclusions included those outside the 18-70 age range, prior T2D history, pregnancy, and animal studies. Rayyan software facilitated article screening, STATA 18 performed meta-analysis, and bias was assessed using JBI tools. The study is registered in PROSPERO (ID: CRD42023414096). Results: A total of 173 articles were retrieved, of which 23 (11.6%) remained for extraction. 13 cohort studies with 11.551.026 participants were included for the meta-analysis, which found that the COVID-19 population had 1.4 greater risk of being diagnosed with T2D in comparison with the population without COVID-19or with other respiratory diseases. The other study designs were narratively analyzed, describing similar results as the meta-analysis. Discussion: New onset T2D is a potential consequence of LC. While T2D increases COVID-19 complications, the relationship appears bidirectional. Given the novelty of the topic and potential newer studies, further reviews are needed to understand LC’s impact on chronic diseases like T2D globally. Further studies should be carried out on this specific topic that could raise the burden of T2D between all the other symptoms that may be caused by LC. In addition, it is necessary to adapt the interventions according to each country’s possibilities.

Resumen Objetivo: El objetivo de esta revisión es aclarar el impacto del COVID-19 en nuevos diagnósticos de DM2. Material y Métodos: Esta revisión se elaboró en base a las guías PRISMA. Dos revisores realizaron una búsqueda en bases de datos, incluyendo artículos desde el 2019 hasta el 20 de abril de 2023 en adultos, diagnosticados al menos una vez con COVID-19, sin diagnóstico previo de DM2. Excluyeron: embarazadas, niños y diabetes mellitus I. Esta revisión se registró en PROSPERO (ID: CRD42023414096) el 6 de abril de 2023. Resultados: Un total de 173 artículos se obtuvieron luego de la búsqueda, de los cuales 23 (11,6%) quedaron para extracción. 13 estudios de cohorte con 11.551.026 participantes se incluyeron en el metaanálisis, que encontraron que la población que tuvo COVID tiene un 1,4 veces más riesgo de ser diagnosticados con DM2 en comparación a quienes no tuvieron el diagnóstico o fueron diagnosticados con otra patología respiratoria. Los diseños de estudio se describieron narrativamente, describiendo resultados similares a los del metaanálisis. Discusión: El nuevo diagnóstico de DM2 es una potencial consecuencia de LC. Mientras aumenta la DM2, aumentan las complicaciones de COVID-19, la relación aparenta ser bidireccional. Ya que estos hallazgos son medianamente recientes, no existe mucha evidencia disponible al respecto, por lo tanto, se requiere un mayor número de estudios al respecto, además de la creación de nuevas políticas de salud pública ad hoc a las posibilidades de cada país.

The outbreak of the Covid-19 pandemic and subsequent lock-down restrictions forced higher education institutions to move towards a fully online mode of delivery. The study explored the teaching and learning experiences of both students and lecturers within such a digitally transformed higher education space. Concerns have however been raised about this sudden move towards the fourth industrial revolution due to the levels of readiness of higher education institutions. A qualitative research approach was followed, and I purposeful selected ten masters' course work students and two lecturers. One-on-one interviews and a focus group discussion were utilised for data generation. The Saldana's thematic method was employed to analyse data. The findings of my research point to both positive and negative experiences of students and lecturers, following the shift to online teaching and learning. Negative experiences highlight the need for support systems to be put in place in a digitally transformed educational milieu.

ABSTRACT Background. Post-COVID syndrome (PCS), characterized by symptoms that persist for more than 4 weeks after initial infection, could increase cardiovascular risk. High-density lipoproteins (HDL) have antiatherogenic functions, such as the ability to promote reverse cholesterol transport (RCT) and antioxidant activity. In this regard, paraoxonase 1 (PON 1) plays a key role. Objective. The aim of this study was to evaluate HDL functions in patients with PCS and compare them with asymptomatic patients (AP) and controls. Methods. The study included 9 patients with PCS, 18 AP and 10 controls. Complete blood count, basic lipoprotein profile, apolipoproteins A-I and B, and inflammatory markers were measured using automated methods. PON 1 activity was evaluated by a spectrophotometric assay, and the 3 steps of RCT, cellular cholesterol (efflux CCE), lecithin-cholesterol acyltransferase (LCAT) activity and cholesteryl ester transfer protein (CETP) activity were evaluated by radiometric assays. Results. There were no differences in sex, age, or general parameters. The AP group had higher PON activity than the control group (94±76 vs. 183±111 vs. 148±58 nmol/mL.min, in controls, AP and PCS, respectively; p=0.049). There were no differences in RCT. Cellular cholesterol efflux (r=-0.45; p=0.049) and CETP (r=- 0.38; p=0.028) had a negative correlation with neutrophil-to-lymphocyte ratio. LCAT had an inverse correlation with ferritin (r=-0.34; p=0.046). Conclusions . Increased antioxidant activity of PON 1 would represent a defensive mechanism against oxidative stress after infection. All the RCT steps had a negative correlation with inflammatory markers. Our findings may explain, at least in part, the link between COVID-19 and atherosclerosis.

RESUMEN Introducción. El síndrome post COVID (SPC), que se caracteriza por síntomas que se extienden superando las 4 semanas post-infección, podría desencadenar aumento en el riesgo cardiovascular. Las lipoproteínas de alta densidad (HDL) presentan funciones antiaterogénicas, como su capacidad para promover el transporte inverso del colesterol (TIC) y su actividad antioxidante, en la que es clave la enzima paraoxonasa 1 (PON 1). Objetivo. Evaluar funcionalidad de HDL en pacientes con SPC comparados con pacientes asintomáticos (PA) y controles. Material y métodos. Se incluyeron 9 individuos con SPC, 18 PA y 10 controles. Se midieron el hemograma, el perfil lipoproteico básico, las apolipoproteínas A-I y B, y marcadores inflamatorios por métodos automatizados. La actividad de PON 1 se evaluó empleando un método espectrofotométrico y los 3 pasos del TIC, eflujo de colesterol (ECC), y actividades de lecitina:colesterol aciltransferasa (LCAT) y proteína transportadora de colesterol esterificado (CETP), por métodos radiométricos. Resultados. No se observaron diferencias en sexo, edad, ni parámetros generales. El grupo PA presentó mayor actividad PON que los controles (94±76 vs. 183±111 vs. 148±58 nmol/mL.min, en controles, PA y SPC, respectivamente; p=0,049). No se observaron diferencias en el TIC. El ECC (r=-0,45; p=0,049) y CETP (r=-0,38; p=0,028) correlacionaron negativamente con el índice neutrófilos/linfocitos. LCAT correlacionó inversamente con la ferritina (r=-0,34; p=0,046). Conclusiones. El incremento de PON 1 en el grupo PA representaría un mecanismo de defensa frente al estrés oxidativo post-infección. Todos los pasos del TIC mostraron una correlación negativa con marcadores inflamatorios. Nuestros resultados podrían explicar, en parte, el vínculo entre COVID y ateroesclerosis.

Abstract Since December 2020, the Argentine State carried out a national vaccination plan to face the Covid-19 pandemic. Despite several initial difficulties, by the end of December 2021, a high percentage of the population had been vaccinated. Given that vaccines and vaccination are widely accepted in the country, this was not surprising at all. However, the campaign also received very harsh objections and attacks from the political and media opposition, giving rise to violent public controversies. My aim is to show that these disputes can be read as updates of a specific historicity, that is, local ways of thinking and organizing the present in relation to schemes of the past that, in turn, make certain futures imaginable and admissible. My analysis is focused on the public discourse of leaders, legislators and politicians from different parties about vaccines and the vaccination plan until mid-2021. This information was obtained through the collection and analysis of written sources from newspaper media, governmental and non-governmental agencies, and social networks and websites. Additionally, I used statistical information to provide a better understanding of the development of the pandemic and vaccination.

Resumen Desde diciembre de 2020, el Estado argentino emprendió un plan nacional de vacunación para enfrentar la pandemia de Covid-19. Pese a varias dificultades iniciales, hacia fines de diciembre de 2021 se había logrado vacunar a un alto porcentaje de la población, algo esperable por la historia de aceptación mayoritaria de las vacunas y la vacunación en el país. Sin embargo, también la campaña fue objeto de durísimos cuestionamientos de la oposición política y mediática. Mi pretensión es mostrar que estas disputas resultan inteligibles en el marco de una específica historicidad, esto es, modos locales de pensar y organizar el presente en relación con esquemas del pasado que, a su vez, hacen que ciertos futuros sean imaginables y admisibles. Mi exposición está basada en el discurso público de gobernantes, funcionarios, legisladores y políticos de distintos partidos sobre las vacunas y su aplicación durante los primeros seis meses de la vacunación, discurso relevado mediante una indagación de fuentes periodísticas, agencias gubernamentales y no gubernamentales y redes sociales y sitios web. Asimismo, incorporé información estadística para una mejor comprensión del desarrollo de la pandemia y la vacunación.

Abstract In this article, I analyze relations between houses, economic practices, and temporalities, in the surroundings of the Arena do Grêmio (Grêmio Foot-Ball Porto Alegrense’s stadium), in Porto Alegre, RS, Brazil. The imbrication between residential and commercial spaces is a central aspect in the study context, evidenced by the activation of a commercial circuit in houses adjacent to this multi-purpose arena. Present the form in which people analyze different temporal markers enable a way to identify flows, commercial practices and the ways in which pandemic temporalities were experienced. I will situate the analysis in cases that allow us to reflect on how the economic and health consequences of the COVID-19 pandemic were experienced inseparably. Based on ethnography, I demonstrate how different temporalities fostered changes in houses, crossed family experiences and modulated expectations for overcoming crisis, representing the advent of a post-pandemic period. article FootBall Foot Ball Alegrenses Alegrense s stadium, stadium , stadium) Alegre RS Brazil context multipurpose multi purpose arena flows COVID19 COVID 19 COVID-1 inseparably ethnography crisis postpandemic post period COVID1 1 COVID-

Resumo Neste artigo, analiso um conjunto de relações que entrelaçam casas, práticas econômicas e temporalidades, nos entornos da Arena do Grêmio, estádio de futebol em Porto Alegre. A imbricação entre espaços residenciais e espaços comerciais é um aspecto central no contexto de estudo, evidenciada pela ativação de um circuito comercial em casas nas adjacências dessa arena multiúso. Apresentar a forma pela qual as pessoas analisam diferentes marcadores temporais se traduziu em um caminho para identificar fluxos, práticas comerciais e os modos pelos quais temporalidades pandêmicas foram vivenciadas. Situarei a análise em casos que permitem refletir sobre como as consequências, econômicas e sanitárias, da pandemia de Covid-19 foram vividas indissociavelmente. A partir da etnografia, demonstro como diferentes temporalidades fomentaram mudanças nas casas, atravessaram experiências familiares e modularam expectativas à superação de crises, representando o advento de um período pós-pandêmico. artigo Grêmio Alegre estudo multiúso fluxos vivenciadas consequências sanitárias Covid19 Covid 19 Covid-1 indissociavelmente etnografia crises póspandêmico. póspandêmico pós pandêmico. pandêmico pós-pandêmico Covid1 1 Covid-

Resumo A pandemia de Covid 19 aprofundou dinâmicas de vulnerabilidade que há muito já eram sentidas por certos agrupamentos sociais. Nesse contexto, a solidez das redes de suporte material e psíquico frequentemente emerge como aquilo que amortece aqueles que foram os efeitos mais corrosivos da pandemia. Neste artigo, trago reflexões sobre esse tema a partir de uma etnografia feita nos ambientes virtuais em que uma importante liderança dos motoristas de aplicativo em Pernambuco se faz presente. Além de identificar algumas das arbitrariedades sofridas pelo grupo de trabalhadores que esse interlocutor representa (publicizadas em seu Instagram), também mapeio como os próprios motoristas se associam para lidar com tais vulnerabilidades. Por fim, demonstro que foi o meu próprio sofrimento psíquico (aprofundado pelo isolamento social da pandemia) que me fez procurar um motorista engajado com a defesa dessa categoria de trabalhadores. 1 sociais contexto artigo presente publicizadas Instagram, Instagram , Instagram) vulnerabilidades fim aprofundado

Abstract The COVID-19 pandemic has deepened dynamics of vulnerability that had long been felt by certain social groups. In this context, the solidity of material and psychological support networks often emerged as what buffers the most corrosive effects of the pandemic. In this article, I reflect on this topic based on an ethnography carried out in virtual environments in which an important leadership of app drivers in Pernambuco is present. In addition to identifying some of the arbitrariness suffered by the group of workers that this interlocutor represents (publicized on his Instagram), I also map how the drivers themselves come together to deal with such vulnerabilities. Finally, I demonstrate that it was my own psychological suffering (deepened by the social isolation of the pandemic) that made me look for a driver committed to defending this category of workers. COVID19 COVID 19 COVID-1 groups context article present publicized Instagram, Instagram , Instagram) vulnerabilities Finally COVID1 1 COVID-

Resumo O estudo analisou a distribuição espacial e as desigualdades sociais na cobertura vacinal para COVID-19 entre crianças de 5 a 11 anos no Brasil. As coberturas vacinais foram calculadas para os municípios brasileiros e analisadas por região geográfica e decis com base no Índice de Desenvolvimento Humano (IDH-M) e expectativa de escolaridade aos 18 anos. Modelos multiníveis foram usados para determinar o coeficiente de partição da variância, e a estatística local bivariada de Moran I foi usada para avaliar a associação espacial. Os resultados mostraram diferenças significativas nas taxas de cobertura vacinal entre os municípios, com menor cobertura nas regiões Norte e Centro-Oeste. Municípios com menor IDH e anos de escolaridade esperados apresentaram menores taxas de cobertura vacinal. A análise de agrupamento bivariado identificou extensas concentrações de municípios nas regiões Norte e Nordeste com baixa cobertura vacinal e baixo desenvolvimento humano, enquanto alguns aglomerados de municípios nas regiões Sudeste e Sul com baixa cobertura localizavam-se em áreas com alto IDH-M. Essas descobertas destacam as desigualdades persistentes em nível municipal na cobertura vacinal entre crianças e a necessidade de intervenções para melhorar o acesso e a cobertura vacinal em áreas mais vulneráveis. COVID19 COVID 19 COVID-1 1 Brasil IDHM M (IDH-M variância CentroOeste. CentroOeste Centro Oeste. Oeste Centro-Oeste humano localizavamse localizavam se IDHM. M. IDH-M vulneráveis COVID1 COVID-

Abstract This study examined the spatial distribution and social inequalities in COVID-19 vaccine coverage among children aged 5-11 in Brazil. First and second dose vaccine coverage was calculated for all Brazilian municipalities and analyzed by geographic region and deciles based on human development index (HDI-M) and expected years of schooling at 18 years of age. Multilevel models were used to determine the variance partition coefficient, and bivariate local Moran’s I statistic was used to assess spatial association. Results showed significant differences in vaccine coverage rates among Brazilian municipalities, with lower coverage in the North and Midwest regions. Municipalities with lower HDI and expected years of schooling had consistently lower vaccine coverage rates. Bivariate clustering analysis identified extensive concentrations of municipalities in the Northern and Northeastern regions with low vaccine coverage and low human development, while some clusters of municipalities in the Southeast and South regions with low coverage were located in areas with high HDI-M. These findings highlight the persistent municipal-level inequalities in vaccine coverage among children in Brazil and the need for targeted interventions to improve vaccine access and coverage in underserved areas. COVID19 COVID 19 COVID-1 511 5 11 5-1 HDIM M (HDI-M 1 age coefficient Morans Moran s association HDIM. M. HDI-M municipallevel municipal level COVID1 COVID- 51 5-

BACKGROUND. South Africa (SA) has committed to eliminating malaria by 2028. However, the initial target was set for 2023. Additionally, the ongoing COVID-19 pandemic and the emergence of drug and insecticide resistance have been identified as potential stumbling blocks in the achievement of this goal. The impact of COVID-19 on the prevalence and distribution of malaria in SA is unclear. OBJECTIVE. To describe the trends and distribution of malaria before and during the pandemic and its associated lockdown strategies in one of the country's malaria-endemic provinces, Mpumalanga Province. METHOD. A descriptive, retrospective and cross-sectional study was conducted using Mpumalanga provincial malaria case data extracted from the provincial District Health Information System 2. The impact of COVID-19 on the prevalence and distribution of malaria was assessed in Mpumalanga Province between 2017 and 2022 using descriptive trend analysis. Malaria cases before (2017 - 2019) and post-COVID-19 (2020 - 2022) were cross-tabulated using Stata version 17. We used χ² tests to test for significant differences, set at p<0.05. RESULTS. During the study period, 25 380 malaria cases were reported, with the majority men (61%) >26 years old, with reported international travel, primarily to Mozambique. Limpopo Province (93%) accounted for most of the locally imported cases. Headaches and fever were the most common symptoms before and post COVID-19, while asymptomatic malaria carriage was higher during and post COVID (p<0.05). Prior to the pandemic reporting of the preferred treatment for uncomplicated malaria, Coartem use was at 53%, declining to 21% thereafter. Although COVID-19-related restrictions on human movement greatly reduced the malaria burden in Mpumalanga Province, the high-risk group (young mobile men) remained unchanged over the study period. Of concern were the marked reduction in the reporting of Coartem doses administered and the increased prevalence of asymptomatic carriage since 2020. The importation of malaria poses one of the biggest challenges to malaria elimination in Mpumalanga Province. CONCLUSION. This study highlighted the impact of COVID-19 and its related lockdown restrictions on the delivery of malaria health services in Mpumalanga Province. If malaria elimination is to be achieved, all aspects of the malaria programme must be strengthened urgently. Additionally, the health system and cross-border collaborations must also be strengthened.

Resumen La situación de la pandemia por COVID-19 provocó cambios en el sistema educativo costarricense y en consecuencia, se implementó una modalidad de educación virtual de emergencia. En esta investigación, el objetivo es examinar la experiencia subjetiva de un grupo de profesionales en docencia de I y II ciclo de la Educación General Básica para adaptarse a la nueva modalidad pedagógica. El diseño metodológico se sustenta en el paradigma fenomenológico, pues se seleccionó una muestra intencional no probabilística con la participación de 20 docentes de las Direcciones Regionales 01-San José Central, 03-San José Norte y 04-San José Oeste. Los resultados obtenidos evidencian debilidades del profesorado en competencias y estrategias de mediación virtual. Se concluye que, pese a los aprendizajes adquiridos, todavía es necesario potenciar el área tecnológica en la comunidad educativa, en respuesta a las demandas de las nuevas generaciones digitales.

Résumé La situation de la pandémie de COVID-19 a entraîné des changements dans le système éducatif costaricien et, par conséquent, une modalité d'enseignement virtuel d'urgence a été mise en place. Dans cette recherche, l'objectif a été d'examiner l'expérience subjective d'un groupe de professionnels de l'enseignement du premier et du deuxième cycle de l'enseignement général de base pour s'adapter à la nouvelle modalité pédagogique. La conception méthodologique a reposé sur le paradigme phénoménologique, car un échantillon intentionnel non probabiliste a été sélectionné avec la participation de 20 enseignants des Directions Régionales 01-San José Central, 03-San José Nord et 04-San José Ouest. Les résultats obtenus révèlent les faiblesses des enseignants en termes de compétences et de stratégies de médiation virtuelle. On conclut que, malgré les apprentissages acquis, il est encore nécessaire de renforcer le domaine technologique dans la communauté éducative, en réponse aux demandes des nouvelles générations numériques.

Abstract The COVID 19 pandemic situation caused changes in the Costa Rican educational system and consequently, an emergency virtual education modality was implemented. In this research, the objective is to examine the subjective experience of a group of professionals teaching I and II cycles of Basic General Education to adapt to the new pedagogical modality. The methodological design is based on the phenomenological paradigm, since a non-probabilistic intentional sample was selected with the participation of 20 teachers from the Regional Directorates 01-San José Central, 03-San José Norte and 04-San José Oeste. The results obtained show weaknesses of the teaching staff in virtual mediation skills and strategies. It is concluded that, despite the learning acquired, it is still necessary to enhance the technological area in the educational community, in response to the demands of the new digital generations.