Pesquisa | SciELO

ABSTRACT The state of Bahia has the third largest equine herd in Brazil, with the horse industry overtaking several sectors of the economy currently. However, animals may be exposed to several pathogenic agents, especially the equine infectious anemia (EIA) virus. EIA is a persistent viral disease with a worldwide distribution and is considered the main infectious disease in horses. Therefore, this study sought data from serological survey EIA in Itapé and Barro Preto municipalities, inserted in the southern Coastal Identity Territory of Bahia, by using the agar gel immunodiffusion test. A total of 1,880 blood serum samples from Equidae older than 6 months were analyzed from 172 properties. The general prevalence of outbreaks was 25.58% (44/172), presenting 40.47% (34/84) in Barro Preto (cocoa zone) and 11.36% (10/88) in Itapé (livestock zone). The prevalence of positive animals in Itapé was 1.01% and in Barro Preto 12.15%. Each assessed property received a questionnaire with emphasis on sanitary management and a booklet containing basic disease information. It was concluded the EIA is endemic in two epidemiologically distinct areas in the Southern Coastal Identity Territory of Bahia, one with a high prevalence in the cocoa zone for both animals and properties, and the other, in livestock zone, with a significantly low prevalence for animals, however also high for properties. Regarding the risk factors, there was a correlation between the species and age of the animals. Mules and the elderly showed a significant association, probably due to the habitat they live in and longer exposure to the virus.

https://doi.org/10.1590/1808-1657000052023

Carbon and Nitrogen Stocks and Microbiological Activity Under Forest-Pasture System and Traditional Pasture in Pernambuco
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Pessôa, Gabriel Carlos Moura

; Piscoya, Victor Casimiro

; Rolim Neto, Fernando Cartaxo

; Araújo Filho, Renisson Neponuceno de

; Melo, Robson Carlos Pereira de

; Pessôa, Uriel Calisto Moura

; Silva, Lucas José de Souza

; Cunha Filho, Moacyr

; Almeida, Rafael Costa Schaidhauer de

; Piscoya, Thaisa Oliveira Folha

; Moraes, Alex Souza

; Gomes Filho, Raimundo Rodrigues

; Medeiros, Raimundo Mainar de

; Saboya, Luciano Marcelo Fallé

; Pedrotti, Alceu

; Holanda, Francisco Sandro Rodrigues

; Fernandes, Milton Marques

; Santos, Luiz Diego Vidal

Floresta e Ambiente

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2022, Volume 29 Nº 2 elocation e20210068

Resumo: En | Texto: En | PDF: En

Abstract An adequate amount of soil organic matter is considered essential for long-term sustainable agriculture, ensuring good productivity. Therefore, the present study quantified carbon and nitrogen stocks and microbiological activity in soil of three different areas: Forest-pasture System, Pasture System and preserved Caatinga - used as a reference of the experiment - located in a semi-arid region, in Watershed of Pajeú River, state of Pernambuco, Brazil. Eight trenches were opened in each system to collect soil samples at depths of 0 - 10, 20 - 30 and 50 - 60 cm, for chemical and microbiological analysis. In general, attributes of soil showed better results of land use in the following order: preserved Caatinga - Forest-pasture System - Pasture System.

https://doi.org/10.1590/2179-8087-floram-2021-0068

Calibration Strategies Applied to Laser-Induced Breakdown Spectroscopy: A Critical Review of Advances and Challenges
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Costa, Vinicius C.

; Babos, Diego V.

; Castro, Jeyne P.

; Andrade, Daniel F.

; Gamela, Raimundo R.

; Machado, Raquel C.

; Sperança, Marco A.

; Araújo, Alisson S.

; Garcia, José A.

; Pereira-Filho, Edenir R.

Journal of the Brazilian Chemical Society

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Dez 2020, Volume 31 Nº 12 Páginas 2439 - 2451

Resumo: En | Texto: En | PDF: En

Over the years, laser-induced breakdown spectroscopy (LIBS) has been reported in the literature as an alternative to traditional methods of analysis, becoming well established among spectroanalytical techniques. LIBS is a technique widely used for qualitative approaches; however, it is necessary considerable effort for use in quantitative analysis, mainly due to severe matrix effects. These limitations make it difficult to broaden the application of LIBS in quantitative analysis. In this sense, this review discusses recent advances in calibration strategies applied in LIBS for minimizing matrix effects and enabling determination with satisfactory accuracy and precision. Applications, advantages, and limitations of the calibration strategies, such as matrix-matching calibration (MMC), internal standardization (IS), standard addition (SA), multi-energy calibration (MEC), one-point gravimetric standard addition (OP GSA), one-point and multi-line calibration (OP MLC), slope ratio calibration (SRC), two-point calibration transfer (TP CT), single-sample calibration (SSC), multiple linear regression (MLR), principal component regression (PCR), partial least squares (PLS) and artificial neural networks (ANN) are discussed.

https://doi.org/10.21577/0103-5053.20200175 426 downloads

Soil water dynamics and yield in maize and Brachiaria ruziziensis intercropping
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Silva, Gabriela Sabrine França

; Andrade Júnior, Aderson Soares de

; Cardoso, Milton José

; Araújo Neto, Raimundo Bezerra de

Pesquisa Agropecuária Tropical

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2020, Volume 50 elocation e59809

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO Em cultivos consorciados, uma alta densidade de plantas pode retardar o acúmulo de biomassa e afetar a disponibilidade hídrica às plantas. Objetivou-se avaliar a dinâmica da água no solo e o desempenho produtivo no consórcio de milho e Brachiaria ruziziensis sob diferentes densidades de semeadura desta forrageira. O experimento foi conduzido em blocos casualizados, com tratamentos associados às densidades de semeadura (2 kg ha-1, 4 kg ha-1, 6 kg ha-1 e 8 kg ha-1) e ambas as espécies em monocultivo como testemunhas. No milho, avaliou-se a produtividade de grãos e, na braquiária, o número de plantas por hectare e as massas verde e seca da parte aérea. O desempenho do consórcio foi avaliado pelo índice de uso eficiente da terra. A dinâmica da água no solo foi monitorada em duas profundidades (0-0,3 m e 0,3-0,6 m), pela técnica de reflectometria no domínio do tempo. A avaliação do armazenamento de água no solo foi realizada a partir de parcelas com quatro dos sistemas de cultivo (milho ou braquiária em monocultivo, e consórcios com as densidades de semeadura extremas), em quatro períodos. O aumento na densidade de semeadura de B. ruziziensis diminuiu a produtividade dos grãos do milho consorciado em 30,8 %. O consórcio usando 2 kg ha-1 de sementes da forrageira proporcionou melhor eficiência no uso da terra (23 %). Ademais, os tratamentos com consórcio promoveram maior extração de água do solo, especialmente nas fases de maior exigência hídrica do milho (e.g., florescimento e enchimento de grãos). Estes sistemas simulam a extração de água em maiores profundidades, quando comparados ao milho em cultivo solteiro.

ABSTRACT In intercropping systems, a high plant density can delay the biomass accumulation and affect the water availability to plants. This study aimed to evaluate the soil water dynamics and the crop yield performance in maize and Brachiaria ruziziensis intercropping under different sowing densities of the forage grass. The experiment was conducted in a randomized block design, with treatments associated to the sowing densities (2 kg ha-1, 4 kg ha-1, 6 kg ha-1 and 8 kg ha-1) and the single cropping for both species as controls. The maize plants were evaluated for grain yield and B. ruziziensis for number of plants per hectare and shoot fresh and dry matter. The intercropping performance was evaluated using the land-use efficiency index. The soil water dynamics was monitored in two soil depths (0-0.3 m and 0.3-0.6 m) by using the time domain reflectometry method. The evaluation of soil water storage was carried out from plots with four of the crop systems (single maize or B. ruziziensis, and intercropping with the extreme sowing densities), at four different times. The increase in the sowing density of B. ruziziensis decreased the grain yield of the intercropped maize by 30.8 %. The intercropping system using 2 kg ha-1 of the grass seeds resulted in the best land-use efficiency (23 %). In addition, the intercropping treatments promoted a higher extraction of water from the soil, mainly at the maize growth stages with higher hydric demand (e.g., flowering and grain filling). These systems stimulate the extraction of water from deeper soil layers, when compared to maize in single cropping.

https://doi.org/10.1590/1983-40632020v5059809 725 downloads

Recurrent kala-azar: report of two cured cases after total splenectomy
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Reinaldo, Luis Gustavo Cavalcante

; Araújo Júnior, Raimundo José Cunha

; Diniz, Thiago Melo

; Moura, Rafael de Deus

; Costa, Dorcas Lamounier

; Eulálio, Kelsen Dantas

; Costa, Carlos Henrique Nery

Revista do Instituto de Medicina Tropical de São Paulo

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2020, Volume 62 elocation e31

Resumo: En | Texto: En | PDF: En

ABSTRACT In Latin America, the causative agent of kala-azar is the intracellular protozoan Leishmania infantum. Most cases in South America are reported in Brazil. Worldwide, it mainly affects Bangladesh, Ethiopia, India, South Sudan and Sudan. Despite the high morbidity and lethality of kala-azar, most infections are asymptomatic. However, a small portion of patients evolves with recurrence of kala-azar becoming symptomatic even after all available drug treatments. Kala-azar is not a formal indication for splenectomy in adults. Splenectomy is recommended as a saving measure, when kala-azar is associated with symptomatic hypersplenism and for drug-resistant cases. In the study, we report two cases of kala-azar with splenomegaly that presented several hospitalizations due to the recurrence of the kala-azar, in addition to hospitalizations for normalizing the blood count. After splenectomy, kala-azar cases and the effects of hypersplenism are cured. Thus, splenectomy should be seen as a surgical treatment option with a curative purpose in patients with recurrent kala-azar, in whom the possibilities of drug therapy have been exhausted and even so they progressed with hypersplenism and clinical repercussions.

https://doi.org/10.1590/s1678-9946202062031 542 downloads

A herbal oil in water nano-emulsion prepared through an ecofriendly approach affects two tropical disease vectors
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Ferreira, Ricardo M.A.

; Duarte, Jonatas L.

; Cruz, Rodrigo A.S.

; Oliveira, Anna E.M.F.M.

; Araújo, Raquel Silva

; Carvalho, José C.T.

; Mourão, Rosa H.V.

; Souto, Raimundo N.P.

; Fernandes, Caio P.

Revista Brasileira de Farmacognosia

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Dez 2019, Volume 29 Nº 6 Páginas 778 - 784

Resumo: En | Texto: En | PDF: En

ABSTRACT Lippia alba (Mill.) N.E.Br. ex Britton & P. Wilson, Verbenaceae, is considered a great source of a bioactive volatile oil. Due to the wide range of known chemotypes, its chemical analysis is very important. Among the several activities of this volatile oil, a potential larvicidal action against Culicidae species is highlighted. However, the low water miscibility of volatile oils limits their application in aqueous media. Oil in water nano-emulsions are in the spotlight of novelty to solve this main problem. Thus, the aim of the present study was to obtain this nanostructured system with L. alba volatile oil (citral chemotype) and evaluate its larvicidal activity against Aedes aegypti and Culex quinquefasciatus larvae. The major compounds were geranial (30.02%) and neral (25.26%). Low mean droplet size (117.0 ± 1.0 nm) and low polydispersity index (0.231 ± 0.004) were observed and no major changes were observed after seven days of storage. LC50 values against C. quinquefasciatus and A. aegypti third-instar larvae were respectively 38.22 and 31.02 ppm, while LC90 values were, respectively, 59.42 and 47.19 ppm. The present study makes use of a low energy, solvent-free and ecofriendly method with reduced costs. Thus, this paper contributes significantly to phyto-nanobiotechnology of larvicidal agents, opening perspectives for the utilization of L. alba volatile oil in integrated practices of vector control.

https://doi.org/10.1016/j.bjp.2019.05.003 545 downloads

Comparação entre ingestão ideal de calorias mais alto teor de proteínas e ingestão calórico-proteica recomendada em pacientes críticos: um ensaio clínico fase II, prospectivo, randomizado e controlado
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Azevedo, José Raimundo Araújo de

; Lima, Hugo Cesar Martins

; Montenegro, Widlani Sousa

; Souza, Suellen Christine de Carvalho

; Nogueira, Ivna Raquel Olimpio Moreira

; Silva, Marilia Martins

; Muniz, Nicolli de Araujo

Revista Brasileira de Terapia Intensiva

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Jun 2019, Volume 31 Nº 2 Páginas 171 - 179

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Avaliar as diferenças entre os desfechos da terapia nutricional com ingestão ideal de calorias mais alto teor proteico e do padrão de cuidados nutricionais em pacientes críticos adultos. Métodos: Randomizamos pacientes com previsão de permanecer na unidade de terapia intensiva por pelo menos 3 dias. No grupo com ingestão ideal de calorias mais alto teor proteico, a necessidade de ingestão calórica foi determinada por calorimetria indireta e a ingestão proteica foi estabelecida em níveis de 2,0 a 2,2g/kg/dia. O grupo controle recebeu calorias em nível de 25kcal/kg/dia e 1,4 a 1,5g/kg/dia de proteínas. O desfecho primário foi o escore do sumário do componente físico obtido aos 3 e 6 meses após a randomização. Os desfechos secundários incluíram força de preensão manual quando da alta da unidade de terapia intensiva, duração da ventilação mecânica e mortalidade hospitalar. Resultados: A análise incluiu 120 pacientes. Não houve diferença significante entre os dois grupos em termos de calorias recebidas. Contudo, a quantidade de proteínas recebidas pelo grupo com nível ideal de calorias mais alto teor de proteínas foi significantemente mais alta do que a recebida pelo grupo controle. O escore do sumário componente físico aos 3 e 6 meses após a randomização não diferiu entre ambos os grupos, assim como não diferiram os desfechos secundários. Entretanto, após ajuste para covariáveis, um delta proteico negativo (proteínas recebidas menos a necessidade proteica predeterminada) se associou com escore do sumário do componente físico mais baixo nas avaliações realizadas 3 e 6 meses após a randomização. Conclusão: Neste estudo, a estratégia com ingestão calórica ideal mais elevado teor proteico não pareceu melhorar a qualidade de vida física em comparação aos cuidados nutricionais padrão. Contudo, após ajuste para covariáveis, um delta proteico negativo se associou com escores do sumário do componente físico mais baixos nas avaliações realizadas aos 3 e aos 6 meses após a randomização. Esta associação ocorreu independentemente do método de cálculo do alvo proteico.

ABSTRACT Objective: To evaluate differences in outcomes for an optimized calorie and high protein nutrition therapy versus standard nutrition care in critically ill adult patients. Methods: We randomized patients expected to stay in the intensive care unit for at least 3 days. In the optimized calorie and high protein nutrition group, caloric intake was determined by indirect calorimetry, and protein intake was established at 2.0 to 2.2g/kg/day. The control group received 25kcal/kg/day of calories and 1.4 to 1.5g/kg/day protein. The primary outcome was the physical component summary score obtained at 3 and 6 months. Secondary outcomes included handgrip strength at intensive care unit discharge, duration of mechanical ventilation and hospital mortality. Results: In total, 120 patients were included in the analysis. There was no significant difference between the two groups in calories received. However, the amount of protein received by the optimized calorie and high protein nutrition group was significantly higher compared with the control group. The physical component summary score at 3 and 6 months did not differ between the two groups nor did secondary outcomes. However, after adjusting for covariates, a negative delta protein (protein received minus predetermined protein requirement) was associated with a lower physical component summary score at 3 and 6 months postrandomization. Conclusion: In this study optimized calorie and high protein strategy did not appear to improve physical quality of life compared with standard nutrition care. However, after adjusting for covariates, a negative delta protein was associated with a lower physical component summary score at 3 and 6 months postrandomization. This association exists independently of the method of calculation of protein target.

https://doi.org/10.5935/0103-507x.20190025 2011 downloads

Nanosuspension of quercetin: preparation, characterization and effects against Aedes aegypti larvae
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Pessoa, Leticie Zulmira da Silva

; Duarte, Jonatas Lobato

; Ferreira, Ricardo Marcelo dos Anjos

; Oliveira, Anna Eliza Maciel de Faria Motta

; Cruz, Rodrigo Alves Soares

; Faustino, Silvia Maria Mathes

; Carvalho, José Carlos Tavares

; Fernandes, Caio Pinho

; Souto, Raimundo Nonato Picanço

; Araújo, Raquel Silva

Revista Brasileira de Farmacognosia

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Out 2018, Volume 28 Nº 5 Páginas 618 - 625

Resumo: En | Texto: En | PDF: En

Abstract Aedes aegypti (Diptera: Culicidae) is the main vector of some neglected diseases, including dengue. It is very important to develop formulations that increase effectiveness of vector control with low toxicity. Quercetin is a plant-derived flavonoid that modulates the development of some insects. The low water solubility of quercetin impairs the development of water-dispersible commercial products. To circumvent this problem, the preparation of nanoformulations is considered promising. Thus, this study aimed to evaluate the effect of bulk and quercetin nanosuspension against A. aegypti larvae and also to investigate their ecotoxicity. Quercetin nanosuspension was produced by a solvent displacement method followed by solvent evaporation and was maintained in two different temperatures (4 and 25 ºC). Its size distribution and zeta potential were monitored along 30 days. The influence of quercetin nanosuspension and bulk-quercetin was investigated at various concentrations against A. aegypti and the green algae Chlorella vulgaris. The quercetin nanosuspension presented higher stability at 4 ºC and negative zeta potential values. Quercetin nanosuspension and bulk-quercetin adversely affected the larvae development, especially at the highest concentrations. Larvae mortality was between 44% and 100% (48 h) for quercetin nanosuspension at 100 and 500 ppm, respectively. The bulk-quercetin induced around 50% mortality regardless the concentration used at this same time-period. Absence of emerging mosquitoes from water was observed on the survival larvae of all the treated groups. Quercetin nanosuspension was less toxic than bulk-quercetin against C. vulgaris, especially at higher concentrations. These data indicate that quercetin nanosuspension may represent a potential larvicide for A. aegypti control, once they induced larvae death and inhibited the survival ones to emerge from water. In addition, it did not demonstrated ecotoxicity against a non-target organism, highlighting its better properties, when compared to the bulk-quercetin.

https://doi.org/10.1016/j.bjp.2018.07.003 1051 downloads

Small Bowel Stricture Mimicking Megacolon in a Patient with Crohn's Disease
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Fernandes, Samuel Raimundo

; Correia, Luís Araújo

; Velosa, José

GE-Portuguese Journal of Gastroenterology

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Dez 2016, Volume 23 Nº 6 Páginas 319 - 321

Resumo: En | Texto: En | PDF: En

https://doi.org/10.1016/j.jpge.2016.03.003 713 downloads

10.

The use of a segmental endoscopic score may improve the prediction of clinical outcomes in acute severe ulcerative colitis
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Raimundo Fernandes, Samuel

; Santos, Patrícia M.

; Moura, Carlos Miguel

; Marques da Costa, Pedro

; Carvalho, Joana Rita

; Valente, Ana Isabel

; Baldaia, Cilénia

; Gonçalves, Ana Rita

; Moura Santos, Paula

; Araújo-Correia, Luís

; Velosa, José

Revista Española de Enfermedades Digestivas

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Nov 2016, Volume 108 Nº 11 Páginas 697 - 702

Resumo: En | Texto: En | PDF: En

Background: Acute severe colitis (ASC) remains a challenging complication of ulcerative colitis. The early identification of patients who will not respond to optimal therapy is warranted. Increasing evidence suggests that endoscopy may play a role in predicting important outcomes in acute severe colitis. Methods: The endoscopic activity of consecutive patients with acute severe colitis was evaluated using the Mayo endoscopic sub-score (Mayo) and the ulcerative colitis endoscopic index of severity (UCEIS). Two segmental indexes were also produced by summing the scores of the rectum and sigmoid (seg-Mayo and seg-UCEIS, respectively). Endpoints included the need for salvage therapy with infliximab or cyclosporine, refractoriness to corticosteroids, and colectomy. Results: Of one hundred and eight patients enrolled in the study, 60 (55.6%) were male; with a median age of 34.5 years (range 15-80). All patients received intravenous steroids. Fifty-nine patients (55.6%) showed an incomplete or absent response to steroids, 35 patients (34.3%) received salvage therapy with infliximab or cyclosporine and 38 patients (33.3%) were colectomized during the index hospitalization or within the first year of follow-up. All scores were able to predict the need for surgery, but only the seg-UCEIS significantly predicted refractoriness to steroids. Conclusions: There was a strong correlation between endoscopic severity and unfavorable outcomes. The UCEIS outperformed the Mayo endoscopic sub-score in all important outcomes. Segmental scoring further improved the performance of the UCEIS.

https://doi.org/10.17235/reed.2016.4470/2016 405 downloads

11.

Severe ischemic colitis following olanzapine use: a Case Report
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Fernandes, Samuel Raimundo

; Alves, Rosa

; Araújo Correia, Luís

; Gonçalves, Ana Rita

; Malaquias, João

; Oliveira, Emília

; Velosa, José

Revista Española de Enfermedades Digestivas

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Set 2016, Volume 108 Nº 9 Páginas 595 - 598

Resumo: En | Texto: En | PDF: En

Ischemic colitis is the most common subtype of intestinal ischemia usually resulting from vasospasm, vessel occlusion or mesenteric hypoperfusion. Neuroleptics have seldom been linked to ischemic colitis by blocking peripheral anticholinergic and antiserotonergic receptors inducing severe gastrointestinal paresis. We report a young patient with severe ischemic colitis requiring surgery due to necrosis of the bowel. After exclusion of other potential causes, olanzapine was admitted as the cause of ischemia. Clinicians should be aware of how to recognize and treat the potentially life-threatening effects of neuroleptics.

https://doi.org/10.17235/reed.2015.3944/2015 699 downloads

12.

New Terpenoids from Croton limae (Euphorbiaceae)
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Sousa, Antonio H.

; Silva Junior, José N.

; Guedes, Maria L. S.

; Braz-Filho, Raimundo

; Costa-Lotufo, Letícia V.

; Araújo, Ana J.

; Silveira, Edilberto R.

; Lima, Mary A. S.

Journal of the Brazilian Chemical Society

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Ago 2015, Volume 26 Nº 8 Páginas 1565 - 1572

Resumo: En | Texto: En | PDF: En

An asymmetrical dimer of kaurane diterpene and monoterpene and four novel diterpenes were isolated from the roots of <italic>Croton limae</italic>, along with kaempferol-3-<italic>O</italic>-glucoside, ombuin- 3-O-rutinoside and acetyl aleuritolic acid. The cytotoxic activity of the kaurane diterpene was evaluated against colorectal adenocarcinoma (HCT-116), ovarian carcinoma (OVCAR-8) and glioma (SF-295) cell lines, exhibiting IC50 values of 7.14, 8.19 and > 10 µg mL−1, respectively.

https://doi.org/10.5935/0103-5053.20150124 1109 downloads

13.

Activity of Fabaceae species extracts against fungi and Leishmania: vatacarpan as a novel potent anti-Candida agent
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Santana, Dandara Braga

; Costa, Raphaella Correia da

; Araújo, Renata Mendonça

; Paula, José Elias de

; Silveira, Edilberto Rocha

; Braz-Filho, Raimundo

; Espindola, Laila Salmen

Revista Brasileira de Farmacognosia

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Ago 2015, Volume 25 Nº 4 Páginas 401 - 406

Resumo: En | Texto: En | PDF: En

AbstractLeishmaniasis and fungal infection treatment efficacy is limited by toxicity and ever increasing resistance to available drugs, requiring development of alternative compounds. The richness of Cerrado plant antimicrobial secondary metabolites justifies screening of Fabaceae species extracts: Enterolobium ellipticum Benth., Sclerolobium aureum (Tul.) Baill. and Vatairea macrocarpa(Benth.) Ducke, against Leishmania(Leishmania) amazonensis, yeasts and dermatophytes. Among the 26 extracts tested, more than 50% of the total demonstrated significant antifungal activity in comparison to the drug controls (minimal inhibitory concentration 0.12 to ≤31.25 µg/ml). Six extracts capable of complete parasitic growth inhibition had the inhibitory concentration index for 50% values from 9.23 to 78.65 µg/ml. The results led to the selection of the V. macrocarpa ethyl acetate root bark extract for chemical fractionation. This plant, traditionally referred to as angelim-do-cerrado or maleiteira, is used to treat superficial mycoses in Amazonia. A previously unreported pterocarpan vatacarpan together with the known compound musizin was isolated. Vatacarpan demonstrated a minimal inhibitory concentration value of 0.98 µg/ml against Candida albicans ATCC 10231, and thus comparable or superior to fluconazole and amphotericin B. The results add to literature's information the ability of pterocarpans to act as antimicrobial agents.

https://doi.org/10.1016/j.bjp.2015.07.012 1294 downloads

14.

Ehlers-Danlos Syndrome associated with cardiomyopathy hypertrophic obstructive
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Pinto, Raimundo José Almeida de Oliveira

; Santos, Adaílton Araújo dos

; Azevedo, Mablo de Castro

; Meira, Saulo Sacramento

Anais Brasileiros de Dermatologia

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Jun 2015, Volume 90 Nº 3 Páginas 220 - 222

Resumo: En | Texto: En | PDF: En

Abstract Ehlers-Danlos syndrome is a rare clinical condition caused by a genetic change that results in the formation of structurally or functionally altered collagen. The clinical manifestations are varied, being the most obvious skin hypermotility and increased joint flexibility, although other systems - such as cardiovascular, respiratory and neurological - may also be affected. This paper presents the report of a patient who sought medical attention with complaints of atypical chest pain. Clinical evaluation enabled hypothetical diagnosis of hypertrophic obstructive cardiomyopathy and Ehlers-Danlos syndrome. Initial electrocardiogram, echocardiogram and 24 hours holter allowed the confirmation of the first hypothesis. A skin biopsy performed later associated clinical data and confirmed the second hypothesis.

https://doi.org/10.1590/abd1806-4841.20153824 2280 downloads

15.

Rhinosinusitis: evidence and experience. A summary
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Anselmo-Lima, Wilma T.

; Sakano, Eulália

; Tamashiro, Edwin

; Nunes, André Alencar Araripe

; Fernandes, Atílio Maximino

; Pereira, Elizabeth Araújo

; Ortiz, Érica

; Pinna, Fábio de Rezende

; Romano, Fabrizio Ricci

; Padua, Francini Grecco de Melo

; Mello Junior, João Ferreira de

; Teles Junior, João

; Dolci, José Eduardo Lutaif

; Balsalobre Filho, Leonardo Lopes

; Kosugi, Eduardo Macoto

; Sampaio, Marcelo Hamilton

; Nakanishi, Márcio

; Santos, Marco César Jorge dos

; Andrade, Nilvano Alves de

; Mion, Olavo de Godoy

; Piltcher, Otávio Bejzman

; Fujita, Reginaldo Raimundo

; Roithmann, Renato

; Voegels, Richard Louis

; Guimarães, Roberto Eustaquio Santos

; Meirelles, Roberto Campos

; Santos, Rodrigo de Paula

; Nakajima, Victor

; Valera, Fabiana Cardoso Pereira

; Pignatari, Shirley Shizue Nagata

Brazilian Journal of Otorhinolaryngology

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Fev 2015, Volume 81 Nº 1 Páginas 8 - 18

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1016/j.bjorl.2014.11.005 7696 downloads

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