ABSTRACT A novel inclusion complexes nanofibrous membrane fluorescent sensor was prepared for recognizing F- via electrospinning and host–guest interaction. The host α-cyclodextrin on the surface of the electrospun nanofiber membrane is assembled into the guest azobenzene molecule which modified with F- fluorescent probe, and the formation of the inclusion complex is fixed on the surface of the nanofibrous membrane without external force, to prepare a novel surface controllable composite nanofiber membrane for F- detection. The inclusion complexes nanofibrous membrane exhibited favourable sensitivity and selectivity for F-. The introduction of F- would result in notable fluorescent decreasing of the membrane, but the other most common anions would not disturb the detection of F-. Moreover, this nanofibrous membrane was not only a fluorescent sensor for detecting F-, but also a good adsorbent for F- in solution.

Abstract Background: Fava beans (FBs) have long been used as food, and their principal disadvantage is derived from their haemotoxicity. We hypothesized that FB ingestion alters the intestinal gene expression pattern, thereby inducing an immune response. Results: In-depth sequence analysis identified 769 differentially expressed genes (DEGs) associated with the intestine in FB-treated DBA/1 mouse intestines. The identified genes were shown to be associated with biological processes (such as response to stimulus and immune system processes), human disease pathways (such as infectious diseases, endocrine and metabolic diseases, and immune diseases), and organismal system pathways (such as the digestive system, endocrine system, environmental adaptation, and immune system). Moreover, plasma total immunoglobulin E (IgE), histamine, interleukin (IL)-4 and IL-13 levels were significantly increased when the mice were treated with FBs. Conclusions: These results demonstrated that FBs affect the intestinal immune response and IgE and cytokine secretion in DBA/1 mice.

A novel nanofibrous film chemosensor was designed and fabricated for detecting Fe3+. It displayed good sensitivity and selectivity as a sensing material for Fe3+. The addition of Fe3+ would induce obvious fluorescent quenching of the nanofibrous film and the other common metal ions did not interfere in the recognition of Fe3+. The detection limit for Fe3+ of this sensing material was calculated to be 10.63 μmol L-1. Moreover, the nanofibrous film could not only be regarded as a chemosensor for detecting Fe3+, but also as an adsorbent to remove Fe3+ with high efficiency in solution. The adsorption capacity was calculated to be 13.93 mg g-1 of Fe3+/nanofibrous film from Langmuir plot.

ABSTRACT: Aiming to mitigate the aerodynamic heating during hypersonic re-entry, the aerothermodynamic optimization of aerospace plane airfoil leading edge is conducted. Lift-to-drag ratio at landing condition is taken as a constraint to ensure the landing aerodynamic performance. First, airfoil profile is parametrically described to be more advantageous during the optimization process, and the Hicks-Henne type function is improved considering its application on the airfoil leading edge. Computational Fluid Dynamics models at hypersonic as well as landing conditions are then established and discussed. Design of Experiment technique is utilized to establish the surrogate model. Afterwards, the previously mentioned surrogate model is employed in combination with the Multi-Island Genetic Algorithm to perform the optimization procedure. NACA 0012 is taken as the baseline airfoil for case study. The results show that the peak heat flux of the optimal airfoil during hypersonic flight is reduced by 7.61% at the stagnation point, while the lift-to-drag remains almost unchanged under landing condition.

A novel nanofibrous film chemosensor was fabricated by copolymerization and electrospinning, which exhibited signaling behaviors for Zn2+. Upon addition of Zn2+, the sensor film exhibited obvious fluorescence enhancement in a linear fashion. Owing to a larger surface area and high permeability, the selectivity and sensitivity of the nanofibrous film for Zn2+ were satisfactory and achieving a limit of detection of 1.95 × 10-5 mol L-1. Moreover, this material could serve as an adsorbent for Zn2+, as the adsorption capacity was 11.45 mg of Zn2+ ions per gram of nanofibrous film.