Abstract Rosa roxburghii Tratt polysaccharide (RRTP) has various physiological functions that benefit the human body. Therefore, improving the extraction rate of RRTP is of crucial for its promotion and application. In this study, RRTP was extracted using an intermittent ultrasound-assisted enzymatic method, and the effects of five factors on the extraction rate of RRTP were studied using a single factor test and response surface methodology. The regression equation model was significant and had good reliability, and the enzyme concentration, liquid-solid ratio and ultrasonic temperature exhibited a positive and significant effect on the RRTP content. The optimal extraction conditions were a power of 360 W, an enzyme concentration of 2.0%, a liquid-solid ratio of 40 mL/g, an ultrasonic temperature of 60 °C and an ultrasonic time of 25 min. Under these conditions, the crude polysaccharide of RRT (CRRTP) yield was 15.03%, and the RRTP content was 4.50%. The RRTP comprised mannose, rhamnose, galacturonic acid, glucose, galactose and arabinose with molar percentages of 3.39%, 2.91%, 26.73%, 35.16%, 21.21% and 10.61% by High Performance Liquid Chromatography (HPLC), respectively. These results suggested that the intermittent ultrasonic-assisted enzymatic method can improve the extraction rate of RRTP.

Abstract The aim of this study is to observe the clinical efficacy of enteral nutrition support therapy in patients with lung cancer chemotherapy in southern China. 212 patients with lung cancer chemotherapy were divided into treatment group and control group, with 30 cases in each group. Patients in the two groups were treated with a normal diet, anti-infection, oxygen inhalation, antispasmodic and asthma, phlegm elimination, correction of acid-base imbalance, and electrolyte disturbance. Patients in the control group ate according to usual dietary habits, and infused intravenously with 20% fat milk 250 mL. 8.5% compound amino acid 250 mL, 10% glucose injection 500 mL and vitamins and other general nutrition support treatment. Patients in the enteral nutrition treatment group were given oral nutritional support for Lishikang integrin-type nutritional solution based on the control group. Patients with hypoproteinemia were supplemented with an appropriate amount of whey protein powder for 2 weeks. Before and after treatment, nutritional assessment, biochemical index monitoring, and adverse reactions were observed in the two groups of patients. Compared with the control group, the enteral nutrition treatment group increased anthropometric values, improved lung function, and increased serum albumin. There was a significant difference between the two groups (P < 0.05). Enteral nutrition support treatment can significantly improve the nutritional status of patients with lung cancer, we need improve the immune function of patients and tolerance to chemotherapy.