Abstract Objectives: To evaluate the influence of photobiomodulation with infrared laser (IRL) in the rat pulp tissue after bleaching, considering the immunolabeling of interleukin (IL)-23 and hypoxia-inducible factor (HIF)-1α. Methodology: The right and left molars of forty rats were divided into groups: Control – with placebo gel and Bleached – with 35% hydrogen peroxide (H2O2). Half of the rats received one IRL application on both sides, establishing a split-mouth design, which resulted in 4 groups with 20 hemi-maxillae each: Control, Bleach, IRL, and Bleached-IRL. Rats (n=10) from each group were euthanized, at 2- and 30-days mark, and the pulp tissue was evaluated using inflammation and immunolabeling scores. Wilcoxon and Mann-Whitney statistical tests were performed (p<0.05). Results: At the 2-days mark, the Bleached group had severe inflammation and necrosis in the occlusal thirds of the pulp, and moderate to severe inflammation in cervical third, whereas the Bleached-IRL had mild to moderate inflammation (p<0.05). At the 30-days mark, there was no inflammation, but tertiary dentine formation in the bleached groups. Regarding IL-23, severe immunolabeling was observed in the Bleached group (p<0.05) at the 2-days mark; at the 30-days mark, there was a reduction in immunolabeling, in which the Bleached group had moderate and the Bleached-IRL group had mild immunolabeling (p>0.05). HIF-1α was more evident at the 2-days mark in the Bleached group, without significant difference with the Bleached-IRL (p>0.05). The difference was observed between the bleached and control groups, without immunolabeling (p<0.05); at the 30-days mark, the Bleached group had reduction in HIF-1α immunolabeling, while the Bleached-IRL had an increase; the difference remained between the bleached and the controls groups (p<0.05) Conclusion: Photobiomodulation using IRL minimized the inflammation and IL-23 immunolabeling in the pulp tissue of rats after dental bleaching, but did not influence significantly the HIF-1α immunolabeling.

Abstract: This study aimed to assess the cyclic fatigue resistance of Genius and EdgeFile X1 reciprocating instruments compared with WaveOne Gold Primary. Twenty Genius (Ultradent) 25.04, 20 Genius 30.04, 20 EdgeFile X1 (EdgeEndo) and 20 WaveOne Gold Primary (Dentsply Maillefer) instruments were included in this study and tested in a static cyclic fatigue testing device, which has an artificial stainless steel canal with a 60° angle of curvature and a 5-mm radius of curvature. All instruments were operated in reciprocation mode until fracture occurred. The number of cycles to failure (NCF) was calculated and time to fracture (TF) was recorded in seconds using a digital chronometer. The mean and standard deviations of NCF and TF were calculated for each reciprocating system and the data were subjected to Kruskal-Wallis one-way analysis of variance and to Dunn's test (p < .05) using SigmaPlot software (Systat software, CA, USA). The fractured surfaces of five instruments from each brand were randomly examined and microphotographed by a low-vacuum environmental scanning electron microscopy – SEM (Tabletop Microscope TM3030, Hitachi, Japan) to confirm the cyclic fatigue fracture. EdgeFile exhibited the highest cyclic fatigue resistance, followed by both Genius files (p < .05). Within the limitations of this in vitro study, EdgeFile X1 instruments had significantly higher cyclic fatigue resistance than did Genius and WaveOne Gold Primary instruments. The cyclic fatigue resistance of both Genius files was higher than that of WaveOne Gold Primary.

Resumo A contagem de plaquetas está associada a doenças inflamatórias como a diabetes mellitus (DM), que, por sua vez, está relacionada de forma bidirecional com periodontite apical e com a doença periodontal. O objetivo deste estudo foi avaliar os efeitos da periodontite apical e/ou da doença periodontal na contagem de plaquetas utilizando o modelo de rato para DM. Oitenta ratos Wistar foram divididos aleatoriamente em 8 grupos (n=10): controle (C), periodontite apical (AP), doença periodontal (PD), periodontite apical com doença periodontal (AP-PD), diabetes mellitus (DM), diabetes mellitus com periodontite apical (DM-AP), diabetes mellitus com doença periodontal (DM-PD) e diabetes mellitus com periodontite apical e doença periodontal (DM-AP-PD). Os ratos foram anestesiados e a DM foi induzida com uma dose única de estreptozotocina diluída na solução tampão citrato. Após 6 dias, o DM foi confirmada. Os animais foram sedados e a periodontite apical foi induzida pela exposição dentária e a doença periodontal foi induzida por ligadura periodontal. Após 30 dias, os animais foram anestesiados e o sangue foi coletado por punção cardíaca. As amostras foram processadas e a contagem média de plaquetas foi obtida. Os dados foram tabulados e submetidos a análise estatística (p <0,05). Os ratos diabéticos apresentaram níveis glicêmicos médios mais elevados em comparação com ratos não diabéticos aos 6 e 36 dias após a indução da DM (p <0,05). Os grupos DM-PD e DM-PD-AP mostraram aumento da contagem média de plaquetas em comparação com os grupos controle e AP (p <0,05). A doença periodontal isolada ou associada à periodontite apical influencia na contagem de plaquetas em modelo de rato para diabetes mellitus.

Abstract Platelet count is associated with inflammatory diseases like diabetes mellitus (DM), which in turn, is related in a bidirectional manner with apical periodontitis and periodontal disease. The aim of this study was to evaluate the effects of apical periodontitis and/or periodontal disease on mean platelet count in a rat model of diabetes mellitus. Eighty Wistar rats were randomly divided into 8 groups (n=10): control (C), apical periodontitis (AP), periodontal disease (PD), apical periodontitis with periodontal disease (AP-PD), diabetes mellitus (DM), diabetes mellitus with apical periodontitis (DM-AP), diabetes mellitus with periodontal disease (DM-PD) and diabetes mellitus with apical periodontitis and periodontal disease (DM-AP-PD). Rats were anesthetized and DM was induced with a single dose of streptozotocin diluted in citrate buffer solution. After 6 days, the DM was confirmed. The animals were sedated and apical periodontitis was induced by dental exposure and periodontal disease was induced by periodontal ligature. After 30 days, animals were anesthetized and the blood was collected by cardiac puncture. Samples were processed and the mean platelet count was obtained. Data were tabulated and subjected to statistical analysis (p<0.05). Diabetic rats had higher mean glycemic levels compared with nondiabetic rats at 6 and 36 days after DM induction (p<0.05). The DM-PD and DM-PD-AP groups showed increased mean platelet count compared to control and AP groups (p<0.05). The periodontal disease alone or associated with apical periodontitis influence mean platelet count in a rat model of diabetes mellitus.

Este artigo apresenta o resultado de uma pesquisa que teve por objetivo principal verificar se o Portal de Periódicos CAPES atende às necessidades de informação de usuários na área de odontologia. Como revisão de literatura, o trabalho traça a evolução, a consolidação e as tendências das bibliotecas digitais de periódicos e analisa as pesquisas existentes sobre o uso do Portal de Periódicos CAPES por usuários da área de saúde e ciências correlatas. O estudo identificou 91 títulos de periódicos de odontologia citados nas referências bibliográficas das teses e dissertações defendidas no período de 2000 a 2005, na Faculdade de Odontologia da UNESP de Araraquara, os quais foram comparados com aqueles que constam do Portal de Periódicos CAPES. Nos resultados são relacionados, para a área de odontologia, os títulos de periódicos citados mas não pertencentes ao Portal, os títulos do Portal não citados nos trabalhos e a frequência de citação de cada título. Essa análise propiciou, também, levantar dados sobre os periódicos de odontologia mais utilizados pelos alunos de pós-graduação da mesma faculdade, para verificar a adequação da coleção de periódicos da sua Biblioteca às necessidades de informação de seus usuários.

This paper presents the results of a study that aimed at verifying if the contents of the CAPES Digital Library of Scientific Journals attend the information needs of users in the area of dentistry. In the literature review, the article traces the evolution, consolidation and trends of digital libraries of electronic journals and analyses the research about the use of the CAPES Digital Library by scholars in the health sciences and correlated areas. The study identified 91 journal titles cited in the bibliography references of the thesis and dissertations defended in the period from 2000 to 2005 at the School of Dentistry of Araraquara, Sao Paulo State University (UNESP) which were compared with those present in the CAPES Digital Library. The results show, for the area of dentistry, the periodicals which were cited but were not in the CAPES Digital Library, the periodicals which were in the CAPES Digital Library but were not cited and the number of times each title was cited. This analysis also gathered data about the journal titles which have the highest citation rates by the graduate students in order to verify the adequacy of the library journal collection to the information needs of the users.