Ultrasound has been considered an additional test to be carried out by specialists in image. Since its inception some specialists as obstetricians or cardiologists have used it in its field with great results. Now, the general practitioners and other specialties are approaching this technique which is quick, safe, accessible, inexpensive, and above all allows you to complete real-time exploration of the patient. Many are beginning to be the countries and societies where the non-specialist physicians in the field of radiology ultrasound performed on a daily basis and more and more studies show the utility of the same in normal clinical practice.

La ecografía ha sido considerada una prueba complementaria que deben realizar los especialistas en imagen. Desde su inicio, determinados especialistas como obstetras o cardiólogos la han utilizado en su campo con grandes resultados. En los últimos años, los médicos generales y de otras especialidades se van acercando a la técnica, que es rápida, inocua, accesible, barata y que, sobre todo, permite completar en tiempo real la exploración del paciente. Muchos son los países y las sociedades donde los médicos no especialistas en Radiología realizan ecografía a diario y cada vez más estudios muestran la utilidad de la misma en la práctica clínica habitual.

A liga Ti-13Nb-13Zr foi produzida por fusão a arco, solubilizada a 1000ºC/1h resfriada em água, forjada a frio, e recozida nas seguintes condições: 1000ºC/1h e 900ºC/30min resfriada em água. As propriedades mecânicas da liga recozida foram avaliadas pelo ensaio de tração em temperatura ambiente. A região elástica foi analisada de acordo com a equação modificada de Ramberg-Osgood, cujo grau de não-linearidade está associado ao parâmetro n. Verificou-se que um tratamento posterior de envelhecimento a 400ºC/3h diminui as diferenças existentes em algumas propriedades mecânicas e melhora a linearidade na região elástica.

Ti-13Nb-13Zr alloy was produced by arc melting, solution treated at 1000°C/1h followed by water quenching, cold forged and annealed at 1000°C/1h or 900°C/30min followed by water quenching. Mechanical properties of this alloy were evaluated by tension tests at room temperature. The elastic region of the stress-strain curve was analyses according to the modified equation of Ramberg-Osgood, which degree of non-linearity is associated to parameter n. It was observed that aging treatment at 400°C/3h, after the annealing, decreases the differences between mechanical properties; moreover, the linearity of elastic region improves.

Background: McCune-Albright Syndrome (MAS) is characterized by precocious puberty, "cafe au lait" skin lesions and polyostotic fibrous dysplasia. It is caused by 4 post-zygotic mutations of Gas protein with a mosaic distribution. Aim: To describe the clinical presentation and to investigate the presence of the Arg by his substitution (R201H) in 14 girls with MAS. Patients and methods: We performed a clinical analysis of the patients and specific allele PCR in DNA obtained from leukocytes. Results: Twelve of 14 patients presented with precocious puberty, one with cyclical vaginal bleeding and one with pathological bone fractures. Eight girls had polyostotic fibrous dysplasia, one had hyperthyroidism, four had pathological fractures, ten had ovarian cysts, six had breast hyperpigmentation and ten had "cafe au lait" skin lesions. We detected the R2O1H mutation in 10 of 14 patients. We found no difference in the severity of symptoms or in the age of presentation between the patients with and without the mutation. Conclusions: The R201H mutation can be detected in white blood cells, in approximately 70% of cases. Patients exhibit wide clinical variability with the same molecular defect. This suggests that tissues have different proportions of mutant cells (Rev Méd Chile 2001; 129: 1365-72)