SUMMARY OBJECTIVE: The aim of this study was to carry out a systematic review of the literature with meta-analysis to evaluate the effect of using oral contraceptive and hormone replacement therapy as a protective factor in the formation of intracranial aneurysms and subarachnoid hemorrhage. METHODS: This is a systematic review of the literature with meta-analysis, using PubMed and Embase as databases and the PRISMA method. Case-control and cohort studies published until December 2022 were included in this review. RESULTS: Four studies were included in this review; three of which were eligible for meta-analysis. Regarding the use of oral contraceptive and the development of subarachnoid hemorrhage, there was a lower risk of aneurysm rupture with an odds ratio 0.65 (confidence interval 0.5–0.85). In the analysis of patients using hormone replacement therapy and developing subarachnoid hemorrhage, there was also a lower risk of aneurysm rupture with an OR 0.54 (CI 0.39–0.74). Only one article analyzed the formation of intracranial aneurysm and the use of hormone replacement therapy and oral contraceptive, and there was a protective effect with the use of these medications. oral contraceptive: OR 2.1 (CI 1.2–3.8) and hormone replacement therapy: OR 3.1 (CI 1.5–6.2). CONCLUSION: The use of hormone replacement therapy and oral contraceptive has a protective effect in intracranial aneurysm rupture and formation.

Acidentes ofídicos são comuns e trazem como potenciais complicações neuromiopatias e doenças cerebrovasculares, estas últimas associadas a distúrbios da coagulação sanguínea. Relatamos sobre uma mulher de 65 anos com hemorragia cerebral intraparenquimatosa associado a acidente ofídico por Bothrops jararaca, ocorrido no Recôncavo Baiano, BA, Brasil. A paciente foi submetida à craniotomia para evacuação cirúrgica do hematoma, com bom desfecho final. Este relato é acompanhado de revisão sobre a associação entre ofidismo e complicações neurológicas, com enfoque as doenças cerebrovasculares. As estatísticas impressionam pela alta incidência de acidente ofídico no mundo, principalmente em países tropicais e chama atenção o seu impacto sócio-econômico. Discutimos os achados clínicos e laboratoriais que identificam quais vítimas apresentam maior risco de apresentar complicações cerebrovasculares a fim de se identificar precocemente esses pacientes, para que possam ser tratados de forma mais precoce e eficaz.

Snakebites are common and lead to potential complications like neuromyopathies and strokes, these last associated with disturbances of blood coagulation. We report on a 65 years old woman of cerebral intraparenchymal hemorrhage associated with snakebite by a Bothrops jararaca that occurred in the Reconcavo of Bahia, BA, Brazil. The patient was submitted to a surgical evacuation of the hematoma, with a good result. This report is accompanied by a revision about the association among snakebite and neurological complications, emphasizing strokes. Statistics reveal a hight incidence of snakebite in the world, mainly in tropical countries and gets attention for his socioeconomic impact. The clinical and laboratorial characteristics to identify the victims that present a high risk of presenting strokes are discussed in order to identify early those patients, so that they may be treated in a more precocious and effective way.

OBJETIVO: Verificar a freqüência de trauma craniencefálico (TCE) nos indivíduos entre 0 e 19 anos, de acordo com o gênero, idade e etiologia. MÉTODO: Estudo descritivo realizado por meio da pesquisa em prontuário e relato das vítimas de trauma craniencefálico com idade até 19 anos, admitidas em hospital de referência para o atendimento a politraumatizados no Estado da Bahia, por um período de 1 ano. RESULTADOS: Amostra constituída de 390 pacientes, dentre os quais 280 (71,8%) eram do sexo masculino. A faixa etária mais acometida foi a de adolescentes (10 a 19 anos) com 177 pacientes (45,4%). A causa mais comum foi a queda de altura (34,4%). Segundo a pontuação na Escala de Coma de Glasgow, 89% dos pacientes sofreram TCE leve. CONCLUSÃO: O grupo de adolescentes foi o mais atingido, sendo a queda de altura a principal causa de TCE, com predomínio do gênero masculino, havendo preponderância do trauma leve.

OBJECTIVE: To verify the frequency of traumatic brain injury (TBI) in the people between 0 and 19 years of age, in accordance to gender, age and cause of trauma. METHOD: Descriptive study made through a period of a year, in all TBI victims, aged until 19 years admitted in a reference trauma center. RESULTS: The sample had a total of 390 patients; 280 (71.8%) were boys. The main age of the victims was between 10 to 19 years (adolescents) with 177 patients (45.4%). The most common cause of trauma was height falls (34.4%). According to the Glasgow Coma Scale, 89% had suffered mild TBI. CONCLUSION: The main group of victims was the adolescents; the most important cause of TBI was height fall, with masculine predominance and mild trauma.