RESUMO Atividade Física (AF) é fator preventivo de doenças e de promoção de saúde. Resiliência (R) é reação positiva diante de uma catástrofe, ameaça ou situação estressante e risco coronariano (RC) é importante no estudo da saúde. O objetivo do estudo foi analisar e correlacionar os níveis de AF, R e RC nos acadêmicos do Curso de Educação Física da UEPA. Estudo de campo, analítico, comparativo e correlacional, realizado de março a maio de 2022 com 60 acadêmicos. Os dados foram coletados através do Questionário de Nível de AF de Baecke, Burema e Frijters (1982), do questionário da Escala de R adaptado por Pesce et al. (2005) e do questionário de avaliação do RC da Universidade Federal de Santa Maria (2000), tratados através dos valores absolutos e relativos, média e desvio padrão, teste χ2, t de Student, ANOVA one way e correlação de Pearson. Os resultados indicam maior prevalência de grau Bom de R, nível de AF Regular e nível de RC Remoto, índice de AF maior nas mulheres e RC nos homens, correlação entre a idade e R e negativa entre a AF e o RC, o que sugere R e RC adequados, porém AF inferior; os homens precisam melhorar sua AF e diminuir o RC.

ABSTRACT Physical Activity (PA) is a predictive factor of diseases and health promotion. Resilience (R) is a positive reaction in the face of a catastrophe, threat or stressful situation, and coronary risk (CR) is important in the study of health. This study aimed to analyse and correlate the levels of PA, R and CR in the students of the Physical Education Course of the UEPA. In addition to the field, analytic, comparative and correlational, conducted from March to May 2022 with 60 students, the data were collected through the Baecke PA Level Questionnaire, the R Scale questionnaire and the UFSM RC assessment questionnaire, treated using absolute and relative values, mean and standard deviation, χ2 test, Student t, ANOVA one way and Pearson correlation. The results indicate a higher prevalence of Good Grade of R, Level of Regular PA and Level of Remote CR, higher PA index in women and CR in men, correlation between age and R and negative between PA and CR, which suggests adequate R and CR, but lower PA; men need to improve their PA and decrease CR.

ABSTRACT Objective: This study aims to report the case of a 69-year-old female patient with a diagnosis of anorectal melanoma (AM) established by immunohistochemistry. Methods: Clinical case report, a descriptive and qualitative study. Results: The patient had a nodular and ulcerative lesion in the anal region, the imaging exams revealed an expansive lesion that affected the rectum and the vaginal wall. The chosen course of treatment was initial surgical intervention, the surgery and postoperative course progressed without complications, and the anatomopathological examination confirmed the diagnosis of invasive malignant melanoma of the distal rectum of anorectal transition. The anatomopathological examination confirmed the diagnosis of invasive malignant melanoma located in the distal rectum of the anorectal transition. Immunohistochemistry analysis showed infiltrative melanoma with microsatellites, as well as peri and intratumoral lymphocytic infiltrate, angiolymphatic invasion, and perineural invasion. The surgical resection margins, ovaries, posterior vaginal wall, and parametrium showed no signs of neoplastic involvement. Following the surgery, the patient began immunotherapy, which she is still undergoing. Conclusions: The survival rate of AM can be improved through various diagnostic and therapeutic modalities. However, further exploration of this topic through clinical studies is necessary to enhance both diagnosis and treatment.

Abstract Objective To analyze the follow-up, in specialized outpatient clinics, of infants reported with congenital syphilis during the penicillin shortage. Method A cross-sectional study was carried out in ten public maternity hospitals affiliated with the Brazilian Unified Health System in the city of Fortaleza, state of Ceará. Clinical records of infants reported with congenital syphilis who were born alive in 2015 were used to describe correlates of attendance at recommended clinical follow-up appointments. Results A total of 469 infants reported with CS from January 1/2015 to December 31/2015 were included in the analysis. The results show that most infants did not attend the follow-up visits (368/469, 78.5%) and the main associated factors are that the follow-up clinic is located in a different hospital from that where the infant was born (OR: 3.7; CI: 2.20-6.22; p< 0.001) and the use of illicit drugs by the mother (OR: 3.2; CI: 1.57-6.87; p= 0.002). Only 33.7% (34/101) were followed until discharge. Conclusion The majority of infants with reported congenital syphilis during this period did not attend the follow-up visits. Public health efforts aimed at reaching the parents of infants with CS should be a priority to ensure appropriate clinical identification and management of the associated outcomes of this vertically transmitted infection.

RESUMO Objetivo: Analisar a tendência na taxa de detecção de sífilis em gestantes (SG) e na taxa de incidência de sífilis congênita (SC) no estado do Ceará. Métodos: Estudo ecológico que utilizou a técnica da série temporal interrompida para analisar os dados mensais de casos de SG e SC obtidos no Departamento de Informática do Sistema Único de Saúde (DATASUS) no período de janeiro de 2015 a julho de 2021. Utilizaram-se o teste de Kernel e a estimativa de Lincoln-Petersen para analisar a significância estatística. Resultados: Em 2015, estimou-se uma taxa de detecção mensal de SG de 5,4 e de incidência de SC de 8,2 por 1 mil nascidos vivos (NV). A implantação da portaria que alterou os critérios de definição de caso de SG e de SC implicou no aumento de 4,9 na taxa de detecção de SG (p<0,0001; IC95% 3,33; 6,61) e na queda de 0,1 na taxa de incidência de SC (p<0,001; IC95% -0,2; -0,1). A pandemia de COVID-19 não impactou na taxa de detecção mensal de SG (p=0,558; IC95% 5,92; 3,22), nem na sua tendência (p=0,7397; IC95% 0,28; 0,3), mas houve aumento de 0,19 na de SC (p<0,001; IC95% 0,1; -0,31). Conclusões: Entre os anos de 2015 e junho de 2021, a tendência na taxa de detecção de SG e na taxa de incidência da SC sofreu impacto das mudanças nos critérios de definição de caso desses agravos propostas pelo Ministério da Saúde e da pandemia de COVID-19.

ABSTRACT Objective: To analyze the trend in the detection rate of Syphilis in Pregnant Women (SP) and in the incidence rate of Congenital Syphilis (CS) in the state of Ceará. Methods: This is an ecological study that used the technique of interrupted time series to analyze monthly data on cases of SP and CS obtained from the Department of Informatics of the Brazilian Unified Health System (DATASUS) from January 2015 to July 2021. The Kernel test and the Lincoln-Petersen estimate were used to analyze the statistical significance. Results: In 2015, a monthly detection rate of SP was estimated at 5.4 and a CS incidence rate of 8.2 per one thousand live births (LB). The implementation of the ordinance that changed the criteria for defining cases of SP and CS resulted in an increase of 4.9 (p<0.0001; 95%CI; 3.33; 6.61) in the detection rate of SP and a decrease of 0.1 on the incidence of CS (p<0.001; 95%CI -0.2; -0.1). The COVID-19 pandemic did not impact the monthly detection rate of SP (p=0.558; 95%CI 5.92; 3.22), nor its trend (p=0.7397; 95%CI 0.28; 0.3), but there was an increase of 0.19 in CS (p<0.001; 95%CI 0.1; -0.31). Conclusion: Between 2015 and June 2021, the trend in the detection rate of SP and in the incidence rate of CS was impacted by changes in the criteria for defining cases of these diseases proposed by the Brazilian Ministry of Health and the COVID-19 pandemic.

Abstract This study aims to carry out a literature review on the important use of mango residues in the food industry as a new source of starch, the extraction of mango starch from the seeds of the residues, highlighting the properties, the rheology and its different applications in industry. A bibliographic search was carried out in the SciELO, GOOGLE Scholar, PubMed, LILACS, CAPES Journal Portal databases, with the keywords: starch preparation from mango seeds, starch properties, application of mango waste in food and rheology. The articles used in this work were scientific articles in full, available and with free electronic access; national and international articles were also used, delimiting a period of time from 2014 to 2019. It is concluded that several studies have shown that starch used as a renewable source can significantly influence various technological processes in the food industry, both and, mainly in the vital metabolism of human food, as in the texture of products. Thus, the various points commented in this review demonstrate that starch is considered more than an energy component and can be extensively studied in its chemical characterizations and also in its technological and nutritional use.

Resumo Este estudo tem como objetivo realizar a revisão de literatura sobre a importante utilização de resíduos de manga na indústria alimentícia como nova fonte de amido, a extração de amido de manga da parte das sementes dos resíduos, ressaltando as propriedades, a reologia e suas diferentes aplicações na indústria. Realizou-se uma pesquisa bibliográfica nas bases de dados SciELO, GOOGLE ACADÊMICO, PubMed, LILACS, PERIÓDICOS CAPES, com as palavras-chave: preparação do amido a partir de sementes de manga (preparation of starch from mango seeds), propriedades dos amidos (properties of starches), aplicação de resíduos de manga em alimentos (application of mango waste in food) e reologia (rheology). Os artigos usados neste trabalho foram publicações do tipo artigos científicos, todos na íntegra, disponíveis e com livre acesso eletrônico; utilizaram-se também artigos nacionais e internacionais, delimitando um período de tempo de 2014 a 2019. Conclui-se que diversos estudos têm demostrado que o amido utilizado como fonte renovável pode influenciar de forma expressiva em vários processos tecnológicos da indústria alimentícia, tanto e, principalmente no metabolismo vital da alimentação humana, como na textura dos produtos. Assim, os diversos pontos comentados nesta revisão demostram que o amido é considerado mais que um componente energético e pode ser bastante estudado nas suas caracterizações químicas e também no seu aproveitamento tecnológico e nutricional.

Abstract Introduction Women with Polycystic Ovary Syndrome (PCOS) have a higher prevalence of Nonalcoholic Fatty Liver Disease (NAFLD) than the general population. PCOS and NAFLD have common metabolic risk factors, however, the role of diet in NAFLD development is still uncertain in PCOS women. Objective To evaluate and compare the dietary patterns and nutritional intake in patients with PCOS with and without NAFLD. Method Cross-sectional study that included patients with PCOS diagnosed according to Rotterdam criteria. All participants were submitted to abdominal ultrasound to investigate liver steatosis. Dietary profile was assessed by 24-hour food recall (24hR), and Food Frequency Questionnaire (FFQ). Diet quality was assessed by the Healthy Eating Index (HEI) adapted for the Brazilian population. Physical activity practice was also assessed. Results 87 participants were included (average age 35.2 ± 5.7 years), among whom, 67 (77%) had NAFLD. The group with PCOS and NAFLD presented higher body mass index (BMI) (34.9 ± 4.5 vs. 30.4 ± 4.9 kg/m2; p = 0.001), Waist Circumference (WC) (103 [97‒113] vs. 95 [87.5‒100] cm; p < 0.001) and were considered physically active less frequently than those without NAFLD (34.3% vs. 60%; p = 0.04). Food intake and dietary patterns assessed by 24hR, FFQ and HEI presented no difference between the groups. Conclusions PCOS women with coexistent NAFLD had higher BMI, WC and were less physically active than those without NAFLD. Dietary evaluation showed that PCOS women with NAFLD had no significant difference in macro and micronutrients or food group intake and diet quality in comparison to those without NAFLD.

ABSTRACT Background: Scorpions are a leading cause of envenomation in Brazil. The species Tityus serrulatus is associated with the most severe cases, especially in children. Despite not being endemic to the state of Santa Catarina, such occurrences have increased more than 500% in the state recently. Therefore, this study aimed to analyze the occurrence of envenomation by T. serrulatus, attended by the Center for Toxicological Information and Assistance of Santa Catarina. Methods: This was a retrospective and descriptive study of the occurrence of T. serrulatus, identified by the agency, from 2014 to 2021 in Santa Catarina, using data obtained by the BI-DATATOX system. Results: A total of 112 occurrences were classified as envenomation. Of these cases, 48.2% were recorded in the Itajaí Valley region and 33% in Greater Florianópolis. Men were involved in 59.8% of these, and the most common age group was 20-39 years (39.3%). Most envenomation occurred in urban areas (89.3%) under non-occupational circumstances (83%). Stings were more frequent on the hands (50.9%). Care was sought within 1 h after the event in 75.9% of the cases, and 94.6% were classified as mild. Conclusions: Occurrence of envenomation involving T. serrulatus in Santa Catarina increased significantly during the study period. Most cases occurred in urbanized areas, which suggests that they might have been transported from other states, and it must be considered that, in the urban environment, scorpions find a large supply of food and shelter and a reduced number of specific predators, allied to parthenogenesis.

ABSTRACT Objective: Reflect on the specificity of anthropological data and map what is discussed in the scientific literature about the challenges of opening this type of document. Methods: First, it carries out a theoretical discussion to understand the specificities of the field of open research data and anthropological research data. Finally, it performs a systematic literature review with the intention of verifying the state of the art of publications on anthropological research data. Results: The results found were analyzed and grouped into five groups of thematic convergence: 1) problem of ethics in opening data on the internet; 2) specific issues between Information Science and Anthropology; 3) communicational and relational demands of the repositories' platforms; 4) specificity of the multimedia data of the subfield called Visual Anthropology; 5) digital repositories for anthropological museums that house research data. Conclusions: The literature on the subject is still small, but it has been growing since 2015, mainly in the English language. It is concluded that there are several specific challenges for the realization of digital repositories for this type of data and that interdisciplinary relationships between Information Science and Anthropology, Communication and Museology are desired to overcome these adversities.

RESUMO Objetivo: Refletir sobre a especificidade dos dados antropológicos e mapear o que existe de discussão na literatura científica sobre os desafios de abertura desse tipo de documento. Método: Primeiramente, realiza uma discussão teórica para compreender as especificidades da área dos dados abertos de pesquisa e dos dados de pesquisas antropológicas. Por fim, realiza uma revisão sistemática de literatura com a intenção de verificar o estado da arte das publicações sobre dos dados de pesquisas antropológicas. Resultado: Os resultados encontrados na revisão sistemática foram analisados e agrupados em cinco grupos de convergência temática: 1) problema da eticidade na abertura de dados na internet; 2) questões específicas entre Ciência da Informação e Antropologia; 3) demandas comunicacionais e relacionais de repositórios digitais para dados antropológicos; 4) especificidade dos dados multimídia da subárea chamada Antropologia Visual; 5) repositórios digitais para museus antropológicos que abrigam dados de pesquisa. Conclusões: A literatura sobre o tema ainda é pequena, mas vem crescendo desde 2015, principalmente na língua inglesa. Conclui-se que há vários desafios específicos para concretização de repositórios digitais para esse tipo de dado e que as relações interdisciplinares entre Ciência da Informação e Antropologia, Comunicação e Museologia são desejadas para superar essas adversidades.

ABSTRACT Objective: to identify the epidemiological profile of victims who suffered sexual violence, in Anápolis - Goiás - Brazil, between the years 2017 to 2020. Methods: descriptive study of quantitative nature. Data from the notification form of sexual violence registered in the Department of Epidemiological Surveillance were used. Chi-square test was used with a significance level of 5% (p<0.05). Results: 850 cases were notified, with the peak in 2020, 82.1% were female, between the age group of two to 10 years (42.2%), brown (61.2%) and single (37.1%). The main conduct carried out after sexual violence was blood collection (21.6%); the main aggressors were the parents (20.9%), the main type of sexual violence was rape (68.7%) and the victims were mainly referred to the Guardianship Council (48.2%). Conclusion: The results point to the need to strengthen interventions to expand the social protection network for children and adolescents.

RESUMEN Objetivo: identificar el perfil epidemiológico de las víctimas que han sufrido violencia sexual, en Anápolis - Goiás - Brasil, entre los años 2017 a 2020. Método: estudio descriptivo de naturaleza cuantitativa. Se utilizaron datos de la ficha de notificación de violencia sexual registrada en el Departamento de Vigilancia Epidemiológica. Se utilizó la prueba de chi cuadrado con un nivel de significación del 5% (p<0,05). Resultados: Fueron notificados 850 casos, con el pico en 2020, siendo 82,1% mujeres, entre el grupo de edad de dos a 10 años (42,2%), morenas (61,2%) y solteras (37,1%). La principal conducta realizada después de la violencia sexual fue la extracción de sangre (21,6%); los principales agresores fueron los padres (20,9%), el principal tipo de violencia sexual fue la violación (68,7%) y las víctimas fueron encaminadas principalmente al Consejo Tutelar (48,2%). Conclusión: los resultados apuntan a la necesidad de reforzar las intervenciones para ampliar la red de protección social de niños y adolescentes.

RESUMO Objetivo: identificar o perfil epidemiológico das vítimas que sofreram violência sexual, em Anápolis - Goiás - Brasil, entre os anos 2017 a 2020. Métodos: estudo descritivo de natureza quantitativa. Foram utilizados dados da ficha de notificação de violência sexual cadastrada no Departamento de Vigilância Epidemiológica. Utilizado o teste qui-quadrado com nível de significância de 5% (p<0,05). Resultados: foram notificados 850 casos, com o pico em 2020, sendo 82,1% do sexo feminino, entre a faixa etária de dois a 10 anos (42,2%), de cor parda (61,2%) e solteira (37,1%). A principal conduta realizada após violência sexual foi a coleta de sangue (21,6%); os principais agressores foram os pais (20,9%), o tipo de violência sexual principal foi estupro (68,7%) e as vítimas foram encaminhadas, principalmente, para o Conselho tutelar (48,2%). Conclusão: os resultados apontam a necessidade de se fortalecer intervenções no sentido de ampliar a rede de proteção social às crianças e adolescentes.

Resumo Este artigo trata do tema da crise ambiental que nos ensina sobre reconhecer a devastação ocasionada pelos processos coloniais e o esforço global por uma emancipação ambiental. Abordamos o conceito de crise ambiental no âmbito do campo de conhecimento antropológico. Objetivamos refletir sobre a tensão, a violência e o conflito na relação entre a sociedade e a natureza. Em um mundo de recursos naturais finitos, destacamos o despreparo do poder público para lidar com os desafios climáticos e impactos do aquecimento global na forma desigual com que atinge a população mundial e a urgência de serviços do Estado para a mitigação de ações predatórias e a necessária inovação de biopolíticas (nacionais e internacionais) de preservação e fiscalização acompanhadas de ampla participação social. antropológico tensão natureza finitos nacionais internacionais social

Abstract This article addresses the theme of environmental crisis. In doing so, it helps us recognize the devastation caused by colonial processes and the global effort for environmental emancipation. As we approach the concept of environmental crisis from within the field of anthropological knowledge, we work to reflect the tensions, violence, and conflicts in the relationship between society and nature. In a world of finite natural resources, we highlight the unpreparedness of public authorities to deal with climate challenges and the unequal ways in which the impacts of global warming affect the world’s population. We highlight the urgency for the need of State services to mitigate predatory actions and the necessary innovation of biopolicies (national and international) of preservation and enforcement, accomplished through broad social participation. so emancipation knowledge tensions violence nature resources worlds s population national international enforcement participation

Abstract The impact of high-speed exercise on the musculoskeletal system of young racehorses has been extensively discussed because of concerns regarding animal health and welfare. This study investigated the correlation between age, degree of ossification of the distal radial epiphysis, sex, and career longevity of Thoroughbred racehorses in Brazil from 2012 to 2015. We performed a retrospective evaluation of 286 dorsopalmar radiographs of the left radiocarpal region of young horses and their racing performance. Distal radial epiphyseal closure was classified into three degrees: A, B, or C. Performance data included the number of races raced, athletic career length, and the number of races per month. The variables were subjected to regression analysis. At the time of radiographic examination, male horses were significantly older than females, and horses with epiphyseal closure degrees differed with age. Age at first race was 33.08±3.81 months, the average of races raced was 18.32±15.14 races, athletic career duration was 20.37±13.82 months, and the number of races raced per month was 0.93±0.46 races. Age influenced (P>0.001) the distal radial epiphyseal closure on racehorses, but sex did not (P=0.218 for males and P=0.275 for females). An inverse association was observed between age at the first race, the number of races raced per month, and athletic career duration. The frequency of race and the age at the first race influenced athletic career duration.

Resumo O impacto do exercício de alta velocidade no sistema musculoesquelético de cavalos de corrida jovens tem sido amplamente discutido devido a preocupações com a saúde e o bem-estar animal. Este estudo investigou a correlação entre idade, grau de ossificação da epífise radial distal, sexo e longevidade da carreira de cavalos Puro Sangue Inglês de corrida no Brasil de 2012 a 2015. Realizamos uma avaliação retrospectiva de 286 radiografias dorsopalmar da região radiocarpica esquerda de cavalos jovens e seu desempenho de corrida. O fechamento epifisário radial distal foi classificado em três graus decrescentes: A, B ou C. Os dados de desempenho incluíram o número de corridas disputadas, duração da carreira atlética e o número de corridas por mês. As variáveis foram submetidas à análise de regressão. No momento do exame radiográfico, os cavalos machos eram significativamente mais velhos que as fêmeas, e os cavalos com graus de fechamento epifisário diferiram com a idade. A idade na primeira corrida foi de 33,08±3,81 meses, a média de corridas disputadas foi de 18,32±15,14 corridas, a duração da carreira atlética foi de 20,37±13,82 meses e o número de corridas realizadas por mês foi de 0,93±0,46 corridas. A idade influenciou (P>0,001) o fechamento da epífise radial distal em cavalos de corrida, mas o sexo não (P=0,218 para machos e P=0,275 para fêmeas). Uma associação inversa foi observada entre a idade na primeira corrida, o número de corridas disputadas por mês e a duração da carreira atlética. A frequência de corrida e a idade na primeira corrida influenciaram a duração da carreira atlética.

Abstract Objective To evaluate the continuation rates of the 52-mg levonorgestrel-releasing intrauterine system (LNG-IUS) during the first 5 years of use, reasons for its discontinuation, bleeding patterns, and new contraceptive choice after the 5th year, in adolescents and young women. Methods The present study was a 5-year prospective cohort conducted in a Family Planning Service of a tertiary hospital in Brazil. We selected 100 healthy women between 15 and 24 years old who used 52-mg LNG-IUS for contraception. The clinical follow-up of these women took place from June 2017 to December 2022. The study evaluated the continuation rates of the method, reasons for its discontinuation, bleeding patterns, and new contraceptive choice after the 5th year. Continuous data were reported as mean ± standard deviation (SD) and range (minimum-maximum). Categorical variables were described as percentages. Results The continuation rates of LNG-IUS were 89.1% (82/92), 82.9% (72/87), 75.3% (64/85), 70.5% (60/85), and 64.2% (54/84) in the 1st, 2nd, 3rd, 4th, and 5th years of use, respectively. The main reason for discontinuation was acne (11/30). Amenorrhea rates were 50, 54.1, 39, 35.7, and 51.8% at 12, 24, 36, 48, and 60 months, respectively. All patients who completed the study and needed contraception after the 5th year opted for long-acting contraceptive methods (LARC). Conclusion The LNG-IUS showed high continuation rates in adolescents and young women in the first 5 years of use. Most patients who completed the study chose a LARC method after the 5th year.

Resumo Objetivo Avaliar as taxas de continuação do sistema intrauterino liberador de levonorgestrel (SIU-LNG) 52 mg durante os primeiros 5 anos de uso, razões de sua descontinuação, padrões de sangramento e nova escolha contraceptiva após o 5° ano, em adolescentes e mulheres jovens. Métodos O estudo foi uma coorte prospectiva de 5 anos realizada em um Serviço de Planejamento Familiar de um hospital terciário no Brasil. Selecionamos 100 mulheres saudáveis entre 15 e 24 anos que usaram o SIU-LNG 52 mg para contracepção. O acompanhamento clínico dessas mulheres ocorreu de junho de 2017 a dezembro de 2022. O estudo avaliou as taxas de continuação do método, razões de sua descontinuação, padrões de sangramento e nova escolha contraceptiva após o 5° ano. Os dados contínuos foram relatados como média ± DP e intervalo (mínimo-máximo). As variáveis categóricas foram descritas como porcentagens. Resultados As taxas de continuação do SIU-LNG foram 89,1% (82/92), 82,9% (72/87), 75,3% (64/85), 70,5% (60/85) e 64,2% (54/84) no 1°, 2°, 3°, 4° e 5° anos de uso, respectivamente. O principal motivo de descontinuação foi a acne (11/30). As taxas de amenorreia foram de 50, 54,1, 39, 35,7 e 51,8% aos 12, 24, 36, 48 e 60 meses, respectivamente. Todas as pacientes que completaram o estudo e necessitaram de contracepção após o 5° ano optaram por métodos contraceptivos de longa duração (LARC). Conclusão O SIU-LNG apresentou altas taxas de continuação em adolescentes e mulheres jovens nos primeiros 5 anos de uso. A maioria das pacientes que completou o estudo escolheu um método LARC após o 5° ano.

ABSTRACT Objective: To analyze the trend in the detection rate of Syphilis in Pregnant Women (SP) and in the incidence rate of Congenital Syphilis (CS) in the state of Ceará. Methods: This is an ecological study that used the technique of interrupted time series to analyze monthly data on cases of SP and CS obtained from the Department of Informatics of the Brazilian Unified Health System (DATASUS) from January 2015 to July 2021. The Kernel test and the Lincoln-Petersen estimate were used to analyze the statistical significance. Results: In 2015, a monthly detection rate of SP was estimated at 5.4 and a CS incidence rate of 8.2 per one thousand live births (LB). The implementation of the ordinance that changed the criteria for defining cases of SP and CS resulted in an increase of 4.9 (p<0.0001; 95%CI; 3.33; 6.61) in the detection rate of SP and a decrease of 0.1 on the incidence of CS (p<0.001; 95%CI -0.2; -0.1). The COVID-19 pandemic did not impact the monthly detection rate of SP (p=0.558; 95%CI 5.92; 3.22), nor its trend (p=0.7397; 95%CI 0.28; 0.3), but there was an increase of 0.19 in CS (p<0.001; 95%CI 0.1; -0.31). Conclusion: Between 2015 and June 2021, the trend in the detection rate of SP and in the incidence rate of CS was impacted by changes in the criteria for defining cases of these diseases proposed by the Brazilian Ministry of Health and the COVID-19 pandemic.

RESUMO Objetivo: Analisar a tendência na taxa de detecção de sífilis em gestantes (SG) e na taxa de incidência de sífilis congênita (SC) no estado do Ceará. Métodos: Estudo ecológico que utilizou a técnica da série temporal interrompida para analisar os dados mensais de casos de SG e SC obtidos no Departamento de Informática do Sistema Único de Saúde (DATASUS) no período de janeiro de 2015 a julho de 2021. Utilizaram-se o teste de Kernel e a estimativa de Lincoln-Petersen para analisar a significância estatística. Resultados: Em 2015, estimou-se uma taxa de detecção mensal de SG de 5,4 e de incidência de SC de 8,2 por 1 mil nascidos vivos (NV). A implantação da portaria que alterou os critérios de definição de caso de SG e de SC implicou no aumento de 4,9 na taxa de detecção de SG (p<0,0001; IC95% 3,33; 6,61) e na queda de 0,1 na taxa de incidência de SC (p<0,001; IC95% -0,2; -0,1). A pandemia de COVID-19 não impactou na taxa de detecção mensal de SG (p=0,558; IC95% 5,92; 3,22), nem na sua tendência (p=0,7397; IC95% 0,28; 0,3), mas houve aumento de 0,19 na de SC (p<0,001; IC95% 0,1; -0,31). Conclusões: Entre os anos de 2015 e junho de 2021, a tendência na taxa de detecção de SG e na taxa de incidência da SC sofreu impacto das mudanças nos critérios de definição de caso desses agravos propostas pelo Ministério da Saúde e da pandemia de COVID-19.

ABSTRACT For patients with end stage renal disease, kidney transplant offers significant survival and quality-of-life advantages compared with dialysis. But for patients seeking transplant who are highly sensitized, waiting times have traditionally been long and options limited. We present the case of a 34-year-old hypersensitized female who underwent renal retransplantation. Histocompatibility tests revealed a calculated panel-reactive antibody of 99.53% with multiple antibodies against class I and II human leucocyte antigens and an eplet analysis was performed. The donor’s potential unacceptable antigens were re-defined and the calculated panel-reactive antibody decreased to 88.38%. After one month the patient received a deceased-donor kidney transplant. Complement dependent cytotoxicity crossmatch was negative; virtual crossmatch and flow cytometry crossmatch with historical serum were positive. High-dose intravenous immunoglobulin and rituximab were added to the thymoglobulin-based induction immunosuppression. Three donor-specific antibodies were detected and plasmapheresis was performed. Renal allograft biopsy revealed no manifestations of rejection. Repeated testing observed a decrease in donor-specific antibodies median fluorescence intensity values. Four months post-transplant, the patient remained with normal graft function without proteinuria. She is receiving a standard maintenance immunosuppression regime with prednisolone, mycophenolate mofetil and tacrolimus. The careful discussion among the transplantation center and histocompatibility laboratory in association with intense immunosuppression and close laboratory monitoring allowed a successful human leukocyte antigen-incompatible deceased donor kidney transplantation in the most critical phase for the occurrence of humoral rejection. It is noteworthy that the new histocompatibility and immunogenetics methodologies provide a more affirmative and comprehensive assessment of mismatch acceptability.

Abstract The aging of the world population poses numerous challenges for organizations, including the retention of an increasingly age diverse workforce. Drawing on psychological contract and social exchange theories, this study examines the effect of age-diversity practices on workers’ subjective well-being and turnover intention through a relational psychological contract. A sample of 257 Portuguese workers answered a questionnaire. Structural equation modelling (SEM) was applied to test the mediation model. The results showed that the existence of age-diversity practices contributes to the development of a relational psychological contract, which, in turn, leads to higher levels of well-being and lower turnover intentions. Theoretical and practical implications of results are discussed.

Resumo O envelhecimento da população mundial acarreta inúmeros desafios para as organizações, entre os quais a retenção de uma força de trabalho cada vez mais diversa em termos de idade. Com base nas teorias do contrato psicológico e da troca social, este estudo examina o efeito das práticas de diversidade etária no bem-estar subjetivo e na intenção de saída dos trabalhadores via contrato psicológico relacional. Uma amostra de 257 trabalhadores portugueses respondeu a um questionário. A análise de equações estruturais foi aplicada para testar o modelo de mediação. Os resultados mostraram que a existência de práticas de diversidade etária contribui para o desenvolvimento de um contrato psicológico do tipo relacional o que, por sua vez, leva a maiores níveis de bem-estar e a menores intenções de saída da organização. As implicações teóricas e práticas dos resultados são discutidas.