Titanium is used in orthopedic and orthodontic implants because it has good corrosion resistance and excellent biocompatibility. Thus, studies seek to obtain a coating to improve the adhesion between the bone and the implant, by modifying the metal’s surface. The objective of this work was to biomimetically coat C.P. Ti with hydroxyapatite doped with silver nitrate, a component with antimicrobial properties, coating the metallic-ceramic composite with a polycaprolactone polymer film, which is known by generate improved implant-tissue interaction, and reducing postoperative complications from bacterial infections. The characterization of the material demonstrated the existence of the coating overall surface of the metallic substrate. The results obtained from the bacterial culture tests with Staphylococcus aureus showed that nitrate was effective in reducing the amount of live bacteria present in the supernatant, as well as those adhered to the surface of the material. In addition, the polymeric coating did not prevent the release of the bactericidal agent, not interfering in the effect there.

Heart diseases affect part of world population and generally involves the functioning of valves. Valves replacement is the most common treatment and the choice between synthetic or natural/biological implants depends on several factors. Synthetic implants have greater durability, whereas biological ones are more biocompatible. This work proposes the use of polymeric coating on titanium metal surface to increase implant biocompatibility. Poly-caprolactone (PCL) has demonstrated greater efficacy for biomedical applications due to its biocompatibility. It can easily form films and coat surfaces. Titanium discs were submitted to alkaline and thermal treatments and coated with 1%PCL and 1%PCL+TiO2. For both conditions, PCL crystals were found in titanium coated surface (SEM and EDX) and X-ray diffractogram confirmed PCL coating. Infrared Spectroscopy spectra showed both PCL and TiO2 characteristic peaks. Moreover, corrosion resistance of coated disc has considerably increased, proving the effectiveness of PCL as coating material and its potential application in cardiac valves.

Biomaterials are effective alternatives for tissue substitution, including the bone tissue, since they do not pose risks of transmission of diseases or immune rejection. Nowadays, there is an interest in new materials capable of being associated with other substances which favor bone formation, especially natural biopolymers, in particular chitosan, which may present a potential for repairing bone defects and forms films that adhere to metal surfaces. Titanium, despite being a material greatly employed in implants because of its excellent physical properties, does not present bioactive characteristics, making it necessary to use methods of surface modification to enhance its biological response, favoring bone formation. This work aims at studying commercially pure titanium (cp-Ti) coating with chitosan using the biomimetic method and the evaluation of the effects of process variables as substrate surface conditions. Subsequently, the incorporation of AgNO3 was studied and its effects on corrosion resistance were evaluated. To evaluate the coating process, several tests were conducted, such as scanning electron microscopy, X-ray diffraction and infrared spectroscopy. From the results obtained, the efficacy of the chitosan film in inhibiting the corrosion of the metals is concluded, which was the target of this study, thus justifying its use for osseointegration and in several implants.