RESUMO Introdução: O exercício físico pode aumentar a capacidade do corpo de se adaptar ao meio ambiente e melhorar a contratilidade do coração. Ao mesmo tempo, pode reestabelecer a circulação sanguínea e aumentar a capacidade pulmonar. Objetivo: Este artigo explora o papel fundamental do esporte na prevenção de doenças cardiovasculares. Métodos: Este estudo conduziu testes em indicadores fisiológicos relacionados, tais como a reologia hemodinâmica em estudantes que regularmente praticam exercício físico e aqueles que não praticam exercício físico. Resultados: Estudantes que praticam exercícios regularmente e aqueles que não o fazem mobilizam uma função cardíaca mais rápida no início do treino, o que demonstra boa adaptabilidade ao esporte. Conclusão: A prescrição de exercícios de preparo físico para estudantes que se exercitam de forma completa tem o efeito mais pronunciado na função vascular. Nível de evidência II; Estudos terapêuticos – investigação de resultados de tratamento.

ABSTRACT Introduction: Physical exercise can enhance the body's ability to adapt to the external environment and improve the contractility of the heart. At the same time, it can help improve blood circulation and increase lung capacity. Objective: This article explores the critical role of sports in the prevention of cardiovascular diseases. Methods: This article conducts tests on related physiological indicators such as hemodynamic rheology for students who regularly participate in physical exercise and those who do not participate in physical exercise. Results: Students who exercise regularly and those who do not exercise mobilize faster cardiovascular function at the beginning of work. This shows good adaptability to sports. Conclusion: The use of fitness exercise prescription by students who exercise comprehensively has the most pronounced effect on improving vascular function. Level of evidence II; Therapeutic studies - investigation of treatment results.

RESUMEN Introducción: El ejercicio físico puede aumentar la capacidad del cuerpo de adaptarse al medio ambiente y mejorar la contractilidad del corazón. Al mismo tiempo, puede restablecer la circulación sanguínea y aumentar la capacidad pulmonaria. Objetivo: Este artículo explora el papel fundamental del deporte en la prevención de enfermedades cardiovasculares. Métodos: Este estudio condujo pruebas en indicadores fisiológicos relacionados, como la reología hemodinámica, en estudiantes que regularmente practican ejercicio físico y los que no lo practican. Resultados: Estudiantes que practican ejercicios regularmente y los que no lo hacen movilizan una función cardíaca más rápida al principio del entrenamiento, lo que demuestra buena adaptabilidad al deporte. Conclusión: La prescripción de ejercicios de preparación física para estudiantes que se ejercitan de forma completa tiene el efecto más pronunciado en la función vascular. Nivel de evidencia II; Estudios terapéuticos – investigación de resultados de tratamiento.

Low-cost ceramic proppants were successfully prepared from natural bauxite and solid waste coal gangue via CaCO3 additive. 40 wt% of bauxite in raw materials was replaced by coal gangue, which significantly reduced the manufacturing costs. The apparent density, bulk density, acid solubility and breakage ratio of the proppant sintered at different temperatures were systematically investigated. The phase composition and morphological structure were determined using X-ray diffraction (XRD) and scanning electron microscopy (SEM). The results show that the amount of liquid phase affected the solid phase reaction velocity by changing sintering mechanism. When the sintering temperature was 1350 °C, the optimum size of the mullite crystal particles and the optimum amount of the liquid phase were observed and the samples exhibited the best performance.

ABSTRACT CONTEXT: Inflammatory myofibroblastic tumors are a rare type of soft-tissue tumor. Inflammatory myofibroblastic tumors are characterized by rearrangements involving the anaplastic lymphoma kinase gene locus on 2p23. Case Report: We report the case of a 67-year-old Chinese male who presented with dysuria and fever. Magnetic resonance imaging showed an irregular prostatic mass with an isointense signal and obscure boundary. Histopathological evaluation showed that the mass consisted mainly of spindle-shaped cells. Immunohistochemical evaluation showed that the tumor cells were negative for anaplastic lymphoma kinase. CONCLUSIONS: Inflammatory myofibroblastic prostate tumors are rare lesions with unclear etiology. The pathological diagnosis is very important.

This study employed a Bac-to-Bac/Bombyx mori bioreactor to mass-produce immunogenic urease subunit B (UreB) from Helicobacter pylori.The signal peptide bombyxin from B. mori was used to promote secretory expression to improve expression levels and was designed and integrated into the UreB gene to generate the Bacmid/BmNPV/(signal peptide)-UreB baculovirus expression system. To determine whether the bombyxin signal peptide resulted in secretory expression of recombinant UreB (rUreB) and to determine the secretory efficiency, we tested the secretory expression level of rUreB in Bm5 cells using ELISA. To further investigate whether secretory expression affected cell viability, cells were evaluated using 0.4% trypan blue staining, and Bacmid/BmNPV/UreB without the signal peptide served as a control. The above recombinant bacmid constructs were injected to silkworm larvae, and the secretory expression level of rUreB was detected using SDS-PAGE and semi-quantitative western blot analysis. The results indicated that the bombyxin signal peptide directed the secretory expression of rUreB and that this expression improved the viability of Bm5 cells. Moreover, the results showed that the expression level of rUreB was 1.5 times higher with the Bacmid/BmNPV constructs containing the bombyxin signal sequence than those without the signal sequence. These results demonstrate that secretory expression can enhance rUreB expression levels and is likely to aid in the large-scale expression and yield of rUreB in silkworm larvae.