Resumen Este artículo analiza las estrategias de nominación utilizadas por políticos en medios de comunicación peruanos durante la cobertura de dos casos de corrupción en los que estuvo en juego la reputación de dos presidentes de la República. Sobre la base del trabajo de Theodoor van Leeuwen (1996), llamamos estrategias de nominación a las diversas formas en que los políticos nombraron a las personas y a los hechos con la finalidad de controlar significados y construir versiones de acuerdo con sus intereses. Como herramienta de análisis, hemos utilizado el modelo de Representación de Actores Sociales de Van Leeuwen (1996), desde la perspectiva del Análisis Crítico del Discurso, el cual entiende el lenguaje como una práctica social e históricamente situada (Fairclough, 1992 y 2003). Los resultados del análisis muestran que los nombres pueden ser poderosas armas políticas; en este sentido, se debe entender que las prácticas de nominación no son un mero ejercicio de rotulación lingüística, sino prácticas sociales que construyen la realidad, pues nombrar es también crear aquello que se nombra.

Abstract This article analyzes the naming strategies used by politicians in the Peruvian media during the coverage of two corruption cases in which the reputation of two presidents of the Republic was at stake. Based on the work of Theodoor van Leeuwen (1996), we call naming strategies the various ways in which politicians named people and facts in order to control meanings and build versions according to their interests. As an analytical tool, we have used Van Leeuwen’s (1996) model of Representation of Social Actors, from the perspective of Critical Analysis of Discourse, which understands language as a socially and historically situated practice (Fairclough, 1992 and 2003). The results of the analysis show that names can be powerful political weapons; in this sense, it should be understood that naming practices are not merely an exercise in linguistic labeling, but social practices that construct reality, since naming is also creating what is named.

BACKGROUND Carrion’s disease (CD) is a neglected biphasic illness caused by Bartonella bacilliformis, a Gram-negative bacteria found in the Andean valleys. The spread of resistant strains underlines the need for novel antimicrobials against B. bacilliformis and related bacterial pathogens. OBJECTIVE The main aim of this study was to integrate genomic-scale data to shortlist a set of proteins that could serve as attractive targets for new antimicrobial discovery to combat B. bacilliformis. METHODS We performed a multidimensional genomic scale analysis of potential and relevant targets which includes structural druggability, metabolic analysis and essentiality criteria to select proteins with attractive features for drug discovery. FINDINGS We shortlisted seventeen relevant proteins to develop new drugs against the causative agent of Carrion’s disease. Particularly, the protein products of fabI, folA, aroA, trmFO, uppP and murE genes, meet an important number of desirable features that make them attractive targets for new drug development. This data compendium is freely available as a web server (http://target.sbg.qb.fcen.uba.ar/). MAIN CONCLUSION This work represents an effort to reduce the costs in the first phases of B. bacilliformis drug discovery.