Aim To compare the profile and overall survival of young adults and elderly people diagnosed with SCC. Methods A retrospective study was carried out at a High Complexity Oncology Unit, between 2010 and 2016. A descriptive analysis, a bivariate analysis using the chi-square and Fisher’s exact test and the Kaplan-Meier estimator were performed. The predictor variables were tested using the log-rank test and those with statistical significance and the literature were maintained for the Cox regression model. Results 282 cases of SCC were recorded, with only 12.4% diagnosed in young adults. The profile was similar between groups, with the majority of cases of the disease occurring in males, smokers and alcohol consumers. The lesions predominantly located on the tongue and were diagnosed in an advanced stage of the disease, resulting in 35.7% of deaths. The median survival time was 30 months in the elderly and 31 months in young people. In the multivariate analysis, age was not statistically significant, only staging and treatment were predictors of reduced overall survival. Conclusion Tumor staging, and treatment were prognostic factors for the disease.

RESUMO Objetivo: Corpos de Civatte são corpos coloidais de queratinócitos apoptóticos localizados na junção dermoepidérmica e que são frequentes em várias dermatoses, inclusive as lesões de líquen plano. O objetivo do presente trabalho foi determinar a presença de corpos de Civatte em uma amostra de biópsias incisionais obtidas a partir de pacientes com diagnóstico de líquen plano oral (LPO). Métodos: Tratou-se de um estudo transversal retrospectivo, realizado com 34 casos cujas lâminas foram coradas pela hematoxilina-eosina, pertencentes ao arquivo de um Laboratório de Patologia Oral de Instituição de Ensino Superior. A amostra obtida foi classificada em lesões brancas e vermelhas a partir dos dados clínicos disponíveis. As análises histológicas foram realizadas em microscópio de luz, nas objetivas de 10x e 40x, com identificação dos corpos de Civatte como presentes ou ausentes. Resultados: Os corpos colóides estavam presentes em 73,5% da amostra total estudada e em 74,2% das lesões brancas. Conclusão: Os corpos de Civatte foram frequentes em todas as amostras analisadas e não devem ser negligenciados como critério de diagnóstico histopatológico em lesões de LPO.

ABSTRACT Objective: Civatte bodies are colloid bodies of apoptotic keratinocytes located at the dermoepidermal junction and are common in several dermatoses, including lichen planus lesions. The present study aimed to determine the presence of Civatte bodies in a sample of incisional biopsies obtained from patients diagnosed with oral lichen planus. Methods: A retrospective cross-sectional study, carried out with 34 slides stained with hematoxylin-eosin from the archive of an Oral Pathology Laboratory of a Higher Education Institution. The sample obtained was classified into white and red lesions from the available clinical data. Histological analyses were performed under a light microscope, with 10x and 40x objectives, identifying the presence or absence of Civatte bodies. Results: Colloid bodies were present in 73.5% the total sample studied and in 74.2% white lesions. Conclusion: The Civatte bodies were frequent in all samples analysed and should thus be considered a criterion for histological diagnosis in lesions of Oral Lichen Planus.

Resumo Objetivo: Descrever o perfil clínico-epidemiológico dos indivíduos com líquen plano bucal, atendidos em um Centro de Referência de Lesões Bucais do Nordeste de Brasil, no período de 2005 a 2020. Métodos: Trata-se de um estudo descritivo, retrospetivo de série de casos, realizado com dados secundários dos indivíduos com diagnóstico clínico e histopatológico de líquen plano bucal. As informações sobre as variáveis sociodemográficas, condições sistémicas e de saúde, estilo de vida e dados clínicos referentes à lesão foram coletadas dos prontuários. Os dados foram analisados de forma descritiva e foi realizado o Teste Exato de Fisher. Resultados: Foram diagnosticados 47 indivíduos com líquen plano bucal. A média de idade foi de 49,51(±14,61) anos; 70,20% eram mulheres; 76,60% eram negros/pardos e 38,30% apresentavam escolaridade até o ensino fundamental; 51,10% apresentavam companheiro(a) e 59,60% não apresentaram doença sistémica. Com relação ao estilo de vida, 44,70% eram alcoólicos e 27,70% fumadores. Os aspetos clínicos da lesão demonstram que a forma reticular acometeu 80,90% dos casos e a mucosa jugal foi o sítio de maior envolvimento (66,00%). Não houve associação estatisticamente significante entre apresentação clínica e género (p=0,34), além da localização anatómica (p=1,0). Conclusões: O perfil epidemiológico dos indivíduos diagnosticados com líquen plano bucal no referido centro consistiu em sua maioria de mulheres, com idade superior a 40 anos, de cor preta ou parda, escolaridade no ensino fundamental, não sendo fumadores nem consumindo bebidas alcoólicas.

Abstract Objective: To describe the clinical-epidemiological profile of individuals with oral lichen planus diagnosed at a Reference Center for Oral Injuries in Northeastern Brazil from 2005 to 2020. Methods: This descriptive, retrospective case series study was conducted with secondary data from individuals with clinical and histopathological diagnosis of oral lichen planus. Information about the patients’ socio-demographic profile, systemic and health conditions, lifestyle, and clinical data regarding the injury was collected from medical records. The data were analyzed descriptively, and the Fisher’s exact test was performed. Results: Oral lichen planus had been diagnosed in 47 individuals. Their socio-demographic characteristics were as follows: mean age of 49.51 years (± 14.61), 70.20% were women, 76.60% were of black ethnicity, 38.30% had an elementary school level, 51.10% had a partner, and 59.60% did not have a systemic disease. Regarding lifestyle, 44.70% were alcohol-addicted and 27.70% smokers. The lesions’ clinical aspects demonstrated that the reticular form affected 80.90% of the cases and the buccal mucosa was the most involved site (66.00%). There was no statistically significant association between clinical aspects and gender (p=0.34), other than the anatomical location (p=1.0). Conclusions: The epidemiological profile of individuals diagnosed with oral lichen planus in the mentioned center consisted mostly of women older than 40 years of black ethnicity, with an elementary school level, who were not smokers or alcohol-addicted. Clinically, the reticular form and the buccal mucosa location were predominant.