Abstract Objective To evaluate the impact of the race (Black versus non-Black) on maternal and perinatal outcomes of pregnant women with COVID-19 in Brazil. Methods This is a subanalysis of REBRACO, a Brazilian multicenter cohort study designed to evaluate the impact of COVID-19 on pregnant women. From February2020 until February 2021, 15 maternity hospitals in Brazil collected data on women with respiratory symptoms. We selected all women with a positive test for COVID-19; then, we divided them into two groups: Black and non-Black women. Finally, we compared, between groups, sociodemographic, maternal, and perinatal outcomes. We obtained the frequency of events in each group and compared them using X2 test; p-values < 0.05 were considered significant. We also estimated the odds ratio (OR) and confidence intervals (CI). Results 729 symptomatic women were included in the study; of those, 285 were positive for COVID-19, 120 (42.1%) were Black, and 165 (57.9%) were non-Black. Black women had worse education (p = 0.037). The timing of access to the health system was similar between both groups, with 26.3% being included with seven or more days of symptoms. Severe acute respiratory syndrome (OR 2.22 CI 1.17–4.21), intensive care unit admission (OR 2.00 CI 1.07–3.74), and desaturation at admission (OR 3.72 CI 1.41–9.84) were more likely to occur among Black women. Maternal death was higher among Black women (7.8% vs. 2.6%, p = 0.048). Perinatal outcomes were similar between both groups. Conclusion Brazilian Black women were more likely to die due to the consequences of COVID-19.

Resumo Objetivo Avaliar o impacto da raça (negra versus não negra) nos desfechos maternos e perinatais de gestantes com COVID-19 no Brasil. Métodos Esta é uma subanálise da REBRACO, um estudo de coorte multicêntrico brasileiro desenhado para avaliar o impacto da COVID-19 em mulheres grávidas. De fevereiro de 2020 a fevereiro de 2021, 15 maternidades do Brasil coletaram dados de mulheres com sintomas respiratórios. Selecionamos todas as mulheres com teste positivo para COVID-19; em seguida, as dividimos em dois grupos: mulheres negras e não negras. Finalmente, comparamos, entre os grupos, os resultados sociodemográficos, maternos e perinatais. Obtivemos a frequência dos eventos em cada grupo e comparamos usando o teste X2; Valores de p <0,05 foram considerados significativos. Também estimamos o odds ratio (OR) e os intervalos de confiança (IC). Resultados 729 mulheres sintomáticas foram incluídas no estudo; desses, 285 foram positivos para COVID-19, 120 (42,1%) eram negros e 165 (57,9%) não eram negros. As mulheres negras apresentaram pior escolaridade (p = 0,037). O tempo de acesso ao sistema de saúde foi semelhante entre os dois grupos, com 26,3% incluídos com sete ou mais dias de sintomas. Síndrome respiratória aguda grave (OR 2,22 CI 1,17–4,21), admissão em unidade de terapia intensiva (OR 2,00 CI 1,07–3,74) e dessaturação na admissão (OR 3,72 CI 1,41–9,84) foram mais prováveis de ocorrer entre mulheres negras. A mortalidade materna foi maior entre as negras (7,8% vs. 2,6%, p = 0,048). Os resultados perinatais foram semelhantes entre os dois grupos. Conclusão Mulheres negras brasileiras tiveram maior probabilidade de morrer devido às consequências da COVID-19.

ABSTRACT Objective: This two-centre cross-sectional study aimed to evaluate whether xerostomia occurrence is associated with oral health-related quality of life (OHRQoL) in patients with end-stage renal disease (ESRD) after the adjustment for potential confounders. Methods: Oral examinations were performed by calibrated examiners for untreated dental caries, periodontitis and tooth loss in 180 adults with ESRD. The presence of xerostomia was determined using the global question “How often does your mouth feel dry?”. OHRQoL was evaluated by the simplified version of the Oral Health Impact Profile (OHIP14) questionnaire. Multivariate zero-inflated negative binomial regression analysis was used to calculate the incidence rate ratios (IRR) for the nonzero scores and odds ratios (OR) of having no impact in OHIP14 scores according to the presence of exposure. Results: In the adjusted model, xerostomia (IRR = 1.57; 95% CI: 1.12 to 2.20) was associated with poorer OHRQoL. The adjusted domain-specific analysis revealed that xerostomia occurrence significantly impacted the psychological disability and social disability, and the chance of having no impact was lower for the psychological discomfort domain (OR = 0.84; 95% CI: 0.12 to 0.98). Conclusion: Xerostomia exert an impact on OHRQoL in patients with ESRD, mainly in the psychological and social disabilities constructs.

RESUMO Objetivo: Este estudo transversal realizado em dois centros teve como objetivo avaliar se a ocorrência de xerostomia está associada à qualidade de vida relacionada à saúde bucal (QVRSB) em pacientes com doença renal crônica em estágio final (DRCEF) após o ajuste para potenciais fatores de confusão. Métodos: Exames bucais foram realizados por examinadores calibrados para cárie dentária não tratada, periodontite e perda dentária em 180 adultos com DRCEF. A presença de xerostomia foi determinada por meio da pergunta global “Com que frequência você fica com a boca seca?”. A QVRSB foi avaliada pela versão simplificada do questionário Oral Health Impact Profile (OHIP-14). A análise multivariada de regressão binomial negativa inflacionada por zero foi usada para calcular as taxas de incidência (IRR) para os escores diferentes de zero e os razões de chance (OR) de não haver impacto nos escores do OHIP-14 de acordo com a presença dA exposição. Resultados: No modelo ajustado, a xerostomia (IRR = 1,57; IC 95%: 1,12 a 2,20) foi associada a pior QVRSB. A análise específica por domínio revelou que a ocorrência de xerostomia impactou significativamente a incapacidade psicológica e a incapacidade social, e a chance de não haver impacto foi menor para o domínio desconforto psicológico (OR = 0,84; IC95%: 0,12 a 0,98). Conclusão: A xerostomia exerce impacto sobre a QVRSB em pacientes com DRCEF, principalmente nos construtos de deficiência psicológica e social.

Resumo O objetivo deste trabalho foi investigar o uso do modelo de rede neural convolucional You Only Look Once (YOLO) para detecção e contagem eficiente de brotos de Eucalyptus sp. em plantações, por meio de fotografias aéreas capturadas por veículos aéreos não tripulados. Para isso, avaliou-se a importância da organização dos dados durante o processo de treinamento do sistema. Foram utilizados dois conjunto de dados para treinar a rede neural convolucional: um consistindo em imagens com um único broto e o outro com pelo menos dez brotos por imagem. Os resultados mostraram altas taxas de precisão e recall para ambos os conjuntos de dados. A rede neural convolucional treinada com imagens contendo dez brotos por imagem apresentou desempenho superior quando aplicada a dados não utilizados durante o treinamento. Portanto, a rede neural convolucional YOLO pode ser usada para detecção e contagem de brotos de clones de Eucalyptus sp. a partir de imagens aéreas capturadas por veículos aéreos não tripulados em áreas florestais. Recomenda-se o uso de imagens contendo dez brotos para compor o conjunto de dados de treinamento para o detector de objetos. (YOLO sp plantações isso avaliouse avaliou se sistema Portanto florestais Recomendase Recomenda objetos

Abstract The objective of this work was to investigate the use of the You Only Look Once (YOLO) convolutional neural network model for the detection and efficient counting of Eucalyptus sp. shoots in stands through aerial photographs captured by unmanned aerial vehicles. For this, the significance of data organization was evaluated during the system-training process. Two datasets were used to train the convolutional neural network: one consisting of images with a single shoot and another with at least ten shoots per image. The results showed high precision and recall rates for both datasets. The convolutional neural network trained with images containing ten shoots per image showed a superior performance when applied to data not used during training. Therefore, the YOLO convolutional neural network can be used for the detection and counting of shoots of Eucalyptus sp. clones from aerial images captured by unmanned aerial vehicles in forest stands. The use of images containing ten shoots is recommended to compose the training dataset for the object detector. (YOLO sp systemtraining system process Therefore detector

RESUMO O desenvolvimento do sistema nervoso humano compõe uma série de eventos fundamentais e interdependentes envolvendo o nascimento, crescimento e maturação neuronal, além da seleção positiva ou negativa de sinapses desses neurônios que participarão da composição de circuitos neurais essenciais à atividade do sistema nervoso. Nesse contexto, em que o ambiente e as relações sociais parecem ser marcadores relevantes para o neurodesenvolvimento, técnicas avançadas de neuroimagem e ferramentas de avaliação comportamental têm demonstrado alterações em regiões cerebrais e funções cognitivas em crianças que se desenvolvem em ambientes de baixo ou alto nível socioeconômico. Considerando os aspectos mencionados, esta revisão teve como objetivo identificar a importância do status socioeconômico no desenvolvimento cerebral infantil, buscando identificar quais são os impactos desses fatores na formação morfológica e fisiológica do sistema nervoso, permitindo maior compreensão da importância dos fatores ambientais nos processos de neurodesenvolvimento. nascimento neuronal contexto neurodesenvolvimento mencionados infantil

ABSTRACT The development of the human nervous system makes up a series of fundamental and interdependent events involving birth, growth, and neuronal maturation, in addition to the positive or negative selection of synapses of these neurons that will participate in the composition of neural circuits essential to the activity of the nervous system. In this context, where environment and social relationships seem to be relevant markers for neurodevelopment, advanced neuroimaging techniques and behavioral assessment tools have demonstrated alterations in brain regions and cognitive functions among children developing in low or high socioeconomic status environments. Considering the aspects mentioned, this review aimed to identify the importance of socioeconomic status in children’s brain development, seeking to identify what are the impacts of these factors on the morphological and physiological formation of the nervous system, allowing a greater understanding of the importance of environmental factors in neurodevelopmental processes. birth growth maturation context neurodevelopment environments mentioned childrens s processes

Abstract Introduction: Eating behaviors acquired in childhood tend to be perpetuated in adulthood, so adherence to a healthy diet from an early age becomes important to prevent the onset of the occurrence of diet-related chronic non-communicable diseases. The aim of this study is to evaluate the food consumption of students in the third cycle of basic education and their parents and its relationship with weight status. Methodology: This is a cross-sectional study. Data from 358 students and 318 parents living on Terceira Island (Azores, Portugal) were included in the study. A questionnaire was developed to collect sociodemographic, dietary habits and anthropometric data, this was applied between May and June 2015. A food frequency questionnaire was used, and weight and height were used to calculate the body mass index. A descriptive analysis of the variables under study was performed and the Mann-Whitney's test was used to compare the means between groups. Results: A high prevalence of pre-obesity/obesity (students: 33.0%; parents: 62.4%) was found. Vegetables are consumed most often by parents while fruits, fast food and sweets are consumed more frequently by students. Normal weight students reported a higher frequency of soy, olive oil, sunflower oil, and sweets compared with overweight students, on the other hand overweight parents reported a higher frequency of consumption of milk, pork, fatty fish, potatoes, vegetables, citrus fruits, and sunflower oil, compared with normal weight parents. Conclusions: Given the high prevalence of pre-obesity/obesity found, as well as the high frequency of consumption of unhealthy foods, it is recommended that health promotion measures be taken in these schools.

Resumen Introducción: Las conductas alimentarias adquiridas en la infancia tienden a perpetuarse en la edad adulta, por lo que la adherencia a una dieta saludable desde edades tempranas cobra importancia para prevenir la aparición de enfermedades crónicas no transmisibles relacionadas con la dieta. El objetivo de este estudio es evaluar el consumo de alimentos de los estudiantes del tercer ciclo de educación básica y sus padres, y su relación con el estado de peso. Metodología: Este es un estudio transversal. Se incluyeron datos de 358 alumnos y 318 padres residentes en la Isla Terceira (Azores, Portugal). Se elaboró un cuestionario para recoger datos sociodemográficos, de hábitos alimentarios y antropométricos, fue aplicado directamente entre mayo y junio de 2015. Se utilizó un cuestionario de frecuencia de alimentos y se utilizó el peso y la talla para calcular el índice de masa corporal. Se realizó un análisis descriptivo de las variables en estudio y se utilizó la prueba de Mann-Whitney para comparar las medias entre grupos. Resultados: Se encontró una alta prevalencia de pre-obesidad/obesidad (estudiantes: 33,0%; padres: 62,4%). Las verduras son consumidas con mayor frecuencia por los padres, mientras que las frutas, la comida rápida y los dulces son consumidos con mayor frecuencia por los estudiantes. Los estudiantes normopeso reportaron una mayor frecuencia de consumo de soya, aceite de oliva, aceite y dulces en comparación con los estudiantes con sobrepeso, mientras que los padres con sobrepeso reportaron una mayor frecuencia de consumo de leche, cerdo, pescado graso, papas, verduras, cítricos y aceite, en comparación con los padres de peso normal. Conclusiones: Dada la alta prevalencia de pre-obesidad/obesidad encontrada, así como la alta frecuencia de consumo de alimentos poco saludables, se recomienda tomar medidas de promoción de la salud en estas escuelas.

Abstract Introduction: Eating behaviors acquired in childhood tend to be perpetuated in adulthood, so adherence to a healthy diet from an early age becomes important to prevent the onset of the occurrence of diet-related chronic non-communicable diseases. The aim of this study is to evaluate the food consumption of students in the third cycle of basic education and their parents and its relationship with weight status. Methodology: This is a cross-sectional study. Data from 358 students and 318 parents living on Terceira Island (Azores, Portugal) were included in the study. A questionnaire was developed to collect sociodemographic, dietary habits and anthropometric data, this was applied between May and June 2015. A food frequency questionnaire was used, and weight and height were used to calculate the body mass index. A descriptive analysis of the variables under study was performed and the Mann-Whitney's test was used to compare the means between groups. Results: A high prevalence of pre-obesity/obesity (students: 33.0%; parents: 62.4%) was found. Vegetables are consumed most often by parents while fruits, fast food and sweets are consumed more frequently by students. Normal weight students reported a higher frequency of soy, olive oil, sunflower oil, and sweets compared with overweight students, on the other hand overweight parents reported a higher frequency of consumption of milk, pork, fatty fish, potatoes, vegetables, citrus fruits, and sunflower oil, compared with normal weight parents. Conclusions: Given the high prevalence of pre-obesity/obesity found, as well as the high frequency of consumption of unhealthy foods, it is recommended that health promotion measures be taken in these schools.

Resumen Introducción: Las conductas alimentarias adquiridas en la infancia tienden a perpetuarse en la edad adulta, por lo que la adherencia a una dieta saludable desde edades tempranas cobra importancia para prevenir la aparición de enfermedades crónicas no transmisibles relacionadas con la dieta. El objetivo de este estudio es evaluar el consumo de alimentos de los estudiantes del tercer ciclo de educación básica y sus padres, y su relación con el estado de peso. Metodología: Este es un estudio transversal. Se incluyeron datos de 358 alumnos y 318 padres residentes en la Isla Terceira (Azores, Portugal). Se elaboró un cuestionario para recoger datos sociodemográficos, de hábitos alimentarios y antropométricos, fue aplicado directamente entre mayo y junio de 2015. Se utilizó un cuestionario de frecuencia de alimentos y se utilizó el peso y la talla para calcular el índice de masa corporal. Se realizó un análisis descriptivo de las variables en estudio y se utilizó la prueba de Mann-Whitney para comparar las medias entre grupos. Resultados: Se encontró una alta prevalencia de pre-obesidad/obesidad (estudiantes: 33,0%; padres: 62,4%). Las verduras son consumidas con mayor frecuencia por los padres, mientras que las frutas, la comida rápida y los dulces son consumidos con mayor frecuencia por los estudiantes. Los estudiantes normopeso reportaron una mayor frecuencia de consumo de soya, aceite de oliva, aceite y dulces en comparación con los estudiantes con sobrepeso, mientras que los padres con sobrepeso reportaron una mayor frecuencia de consumo de leche, cerdo, pescado graso, papas, verduras, cítricos y aceite, en comparación con los padres de peso normal. Conclusiones: Dada la alta prevalencia de pre-obesidad/obesidad encontrada, así como la alta frecuencia de consumo de alimentos poco saludables, se recomienda tomar medidas de promoción de la salud en estas escuelas.

RESUMO: As divergências no temperamento dependem da reação dos animais às pessoas e à diferentes situações sociais e ambientais. Contudo, pouco se sabe acerca da influência de alterações no ambiente pastoril sobre o temperamento dos bovinos. Com isso, a hipótese de trabalho é de que o temperamento dos animais pode ser alterado se mantidos em sistemas pastoris arborizados. Para tanto, objetivou-se avaliar o efeito do componente arbóreo em ambiente pastoril sobre o temperamento de bovinos em pastejo em sistemas integrados de produção agropecuária. Foram avaliados 32 novilhos da raça Angus alocados em dois sistemas pecuária (PEC) e pecuária-floresta (PF) durante o período de dezembro de 2019 a fevereiro de 2020, no qual foi mensurado: o escore de reatividade dos animais; a velocidade de fuga e o número de vocalizações. O modelo estatístico utilizado considerou como efeito fixo de tratamentos e períodos e efeitos aleatórios dos animais, utilizando o procedimento MIXED, as médias foram comparadas pelo recurso lsmeans. A velocidade de saída e número de vocalizações foram similares entre os sistemas de produção. O escore de reatividade foi menor para os animais mantidos no sistema PF quando comparados aos do tratamento PEC. O sistema PF interfere positivamente no temperamento animal em relação ao sistema de produção PEC, observado pelo menor escore de reatividade nos animais mantidos neste sistema. Contudo, o estudo sobre a influência da integração de sistemas sobre o temperamento animal exige mais pesquisas para revelar o potencial deste modelo de produção sobre o comportamento animal.

ABSTRACT: Temperament often depends on the animals’ reaction to people, social and environmental conditions. However, little is known about the influence of changes in the pasture environment on cattle temperament. Thus, this study was designed to evaluate if an animals’ temperament changes in response to being kept in a silvopastoral system. This study evaluated the effect of the tree components in a pasture environment on the temperament of any grazing cattle in integrated crop-livestock systems. A total of thirty-two Angus steers were allocated to either a livestock (L) or livestock-forest (LF) system and observed from December 2019 to February 2020. Each animal was evaluated for their reactivity score, flight speed, and number of vocalizations. The statistical model established that the animals were random effects and that the treatments and periods were fixed effects using the MIXED procedure, and the means were compared using LSMeans. The flight speed and number of vocalizations were similar in both production systems, while the reactivity score was lower for animals kept in the LF system when compared to those in the L system. This suggested that the LF system interferes positively with the animal’s temperament in relation to the L production system. However, additional research is needed to understand the influence of the production system on animal temperament.

RESUMO: Este estudo teve como objetivo avaliar a estrutura da vegetação e o desempenho de novilhas em recria e vacas de descarte em pastagens naturais manejadas em sistema de pastejo rotacionado com lotes “ponta” e “rapador” no período primavera-verão. Os tratamentos foram diferentes intervalos de descanso de 402 e 252 graus-dia (GD), os quais favorecem o crescimento de gramíneas de diferentes grupos funcionais. O delineamento experimental foi em blocos ao acaso com dois tratamentos e três repetições. Os animais de teste foram 24 novilhas no grupo “ponta” e 24 vacas no grupo “rapador”. No estrato entre touceiras, as alturas do pasto maiores que 16 cm foram predominantes em ambos os tratamentos, sendo 1.3 vezes mais frequente no tratamento 402 GD em relação ao tratamento 252 GD. A taxa de lotação média foi 22% maior no tratamento com 252 GD. Embora não tenham sido observadas diferenças para o ganho médio diário de novilhas (0,227 kg.dia-1) e vacas (0,336 kg.dia-1) entre os tratamentos, o ganho de peso por área no período experimental foi maior no tratamento 252 GD. Apesar do sistema de manejo com lotes “ponta” e “rapador” não proporcionar mudanças significativas na estrutura da pastagem, ele permite atingir metas de desempenho satisfatórias em áreas de pastagens naturais.

ABSTRACT: This study evaluated the structure of vegetation and the performance of rearing heifers and cull cows in Campos grasslands managed in the rotational stocking method with first-last stocking in the spring-summer period. The treatments were different rest intervals of 402 and 252 degrees-day, which favor the growth of different functional groups of grasses. A completely randomized block design with two treatments and three repetitions was used. The test animals were 24 heifers in the “first” group and 24 cows in the “last” group. In the stratum between tussock grasses, sward heights greater than 0.16 m were predominant in both treatments, it was 1.3 times more frequent in the 402 DD treatment compared to the 252 DD treatment. Average stocking rate was 22% higher in the 252 DD treatment. Although, no differences were observed for the average daily gain of heifers (0.227 kg.day-1) and cows (0.336 kg.day-1) between treatments, the weight gain per area in the experimental period was greater in the 252 DD treatment. Despite the management system with first and last stoking does not provide significant changes in the structure of the pasture, it allowed to achieve satisfactory performance goals in areas of Campos grassland.

ABSTRACT High acidity and low soil P availability in the soils from the Pampa natural grasslands generally limit the forage growth and economic return. Thus, to increase the economic return and avoid environmental degradation and biodiversity loss due to replacement by intensive cropping systems, it is essential to improve the soil P availability. This study aimed to diagnose the nutritional status of the pluri-specific natural grasslands amended with different history of P sources. Additionally, we also try to indicate the most appropriate range of soil P availability for maximizing forage growth. The experiment started in 1997 in an area of Pampa natural grasslands in the state of Rio Grande do Sul, Brazil. The treatments evaluated the application of Gafsa hyperphosphate (HP) and triple superphosphate (SP) for four years (1997, 1998, 2002, and 2010). Soil and aboveground biomass sampling were performed five times from October 2010 to March 2011 to access aboveground biomass production, botanical composition, soil available P, and N and P nutrition index. Greater P availability in the soil amended with SP produced more forage and resulted in a higher P accumulation than in the soil amended with HP. The ideal range of soil P availability in the soils of natural grasslands ranged from 14 to 20 mg kg˗1, varying for different plant species. The species Paspalum plicatulum and Aristida laevis produce less aboveground biomass and accumulate less P in their tissue than Dichantelium sabulorum and Eustachys uliginosa, and P. notatum. Therefore, areas of natural grasslands dominated by D. sabulorum, E. uliginosa and P. notatum demand higher soil P availability to maintain high forage production. Soil P fertilization of pluri-specific natural grasslands in the Brazilian Pampa biome must consider the dominant forage species in the area and the soil P availability.

RESUMO Objetivo: Avaliar a dor e a mobilidade em pacientes com fraturas transtrocantéricas submetidos à osteossíntese com bloqueio do grupo de nervos pericapsulares (PENG) e comparar a pacientes que não receberam o bloqueio. Métodos: Foram analisados os prontuários de 49 pacientes e coletados dados referentes a: idade, sexo, avaliação anestésica, causa do trauma, locomoção, classificação da fratura, tipo de anestesia utilizada, técnica anestésica, dor, administração de opioide e deambulação com carga parcial. Resultados: Dos 49 pacientes, 17 (34,7%) receberam o bloqueio PENG. Após a cirurgia, a maioria dos pacientes queixou-se de dor e foi administrado opioide (67,3%), sendo a maior frequência no grupo sem o bloqueio PENG (93,3%). A maioria dos pacientes que receberam bloqueio PENG deambularam em até 6h após a cirurgia (52,9%) e todos recuperaram a capacidade de deambular até a alta hospitalar (48h), diferindo do grupo que não recebeu o bloqueio PENG (p = 0,012). Houve diferença significativa entre os grupos em relação à frequência de relatos de dor moderada a forte (p = 0,003). Conclusão: O uso de bloqueio PENG em pacientes com fraturas transtrocantéricas submetidos à osteossíntese pode auxiliar na diminuição da dor pós-operatória, deambulação precoce com carga parcial e menor necessidade de uso de opioides. Nível de Evidência III, Estudo Retrospectivo Comparativo.

ABSTRACT Objective: To evaluate pain and mobility in patients with transtrochanteric fractures subjected to osteosynthesis with pericapsular nerve group (PENG) block and compare with patients who did not receive the block. Methods: The medical records of 49 patients were analyzed and data were collected regarding: age, gender, anesthetic evaluation, cause of trauma, locomotion, fracture classification, type of anesthesia used, anesthetic technique, pain, opioid administration and mobility with partial load. Results: Out of 49 patients, 17 (34.7 %) received PENG block. After surgery, most patients complained of pain and opioids were administered (67.3 %), with greatest frequency in the group without PENG block (93.3 %). Most patients who received PENG block walked within 6 h after surgery (52.9 %) and all recovered the ability to walk until hospital discharge (48 h), different from the group that did not receive PENG block (p = 0.012). The groups showed a significant difference between them regarding the frequency of reports of moderate to severe pain (p = 0.003). Conclusion: The use of PENG block in patients with transtrochanteric fractures subjected to osteosynthesis can help to reduce postoperative pain, early mobility with partial load and less use of opioids. Level of Evidence III, Retrospective Comparative Study.

ABSTRACT The presence of weeds in silvicultural systems has been considered one of the main obstacles to the success of projects designed to recover degraded areas. The aim of this study was to evaluate the selectivity of herbicides applied at post-emergence in the initial growth of seedlings of capixingui (Croton floribundus), açoita-cavalo (Luehea divaricata), and guaritá (Astronium graveolens), in the municipalities of Jaboticabal and Junqueirópolis, state of São Paulo. The experimental design was completely randomized, with four replications, and the treatments consisted of herbicides (g a.i.·ha–1) clethodim + phenoxaprop-p-ethyl (50 + 50), sethoxydim (184), quizalofop-p-ethyl (75), nicosulfuron (50), fluazifop-p-butyl (125), fomesafen (225), haloxyfop-methyl (48), bentazon (720), chlorimuron-ethyl (15), in addition to control without herbicide. The characteristics analyzed were: plant height increase and visual phytointoxication at 7, 14, 21, 28, 35, and 42 days after herbicide application. At the end of the experiment, the shoots of the plants were removed to assess shoot dry matter. The herbicides clethodim + fenoxaprop-p-ethyl, fluazifop-p-butyl, and quizalofop-p-ethyl showed selective potential for the species capixingui, açoita-cavalo, and guaritá. The herbicide chlorimuron-ethyl caused mild intoxication symptoms when applied to seedlings of capixingui and açoita-cavalo; also, it was not selective for the guaritá species grown in Jaboticabal. All species showed selectivity to the herbicides sethoxydim, fomesafen, haloxyfop-methyl, and nicosulfuron, as their growth and initial development were not influenced. The herbicide bentazon caused high percentages of injury to açoita-cavalo plants in both cultivation places, but it did not influence the growth and development of the species.

Abstract Inflammatory bowel diseases are a group of inflammatory disorders of the gastrointestinal tract. Their prevalence is still low in Brazil, but the incidence is increasing annually. A variety of compounds present in Curcuma longa L., particularly curcumin, have been shown to reduce oxidative stress and aid in the prevention of associated diseases. This study aimed to assess the effect of curcumin transdermal gel on oxidative stress and intestinal inflammation in IL-10 knockout mice. Female mice were divided into four groups: a control group (C0) treated with vehicle and three experimental groups treated with transdermal gel containing 50 (C50), 75 (C75), and 100 (C100) mg curcumin kg−1 body weight. Colon malondialdehyde concentrations were lower in C50 and C75 groups. C100 treatment led to reduced catalase activity in the small intestine, whereas C50, C75, and C100 treatments resulted in decreased catalase activity in the colon. In contrast, superoxide dismutase activity increased in the small intestine of C50 and C75 mice and decreased in the colon of C50, C75, and C100 mice. Glutathione S-transferase activity increased in the small intestine and decreased in the colon of C75 animals. These findings suggest that curcumin transdermal gel exerts a protective effect against oxidative stress.

RESUMO INTRODUÇÃO: O setor alimentar é considerado a nível mundial como um dos principais setores de negócios, estando em constante mudança e enfrentando múltiplos desafios. OBJETIVOS: Este artigo tem como objetivo descrever as equipas e produtos finalistas da competição Ecotrophelia Portugal (2017- 2020) como fontes de inovação para o setor alimentar. METODOLOGIA: Foi adotada uma metodologia de análise de conteúdo. Os conteúdos analisados foram recolhidos através do site oficial da Ecotrophelia Portugal. Foram analisadas informações sobre as 41 equipas finalistas da competição entre 2017 e 2020. RESULTADOS: De um modo geral, os finalistas foram maioritariamente mulheres (edição 2017), pertencentes à região Norte (57,4%), seguida da região Centro (27,9%) e Lisboa (13,1%), com a Universidade do Porto (26,2%), a Universidade Católica Portuguesa (Porto: 16,4%) e o Instituto Politécnico de Coimbra (13,1%) a serem as principais instituições de proveniência dos finalistas. As principais categorias dos produtos finalistas foram: snacks (34,1%), sobremesas (17,1%), refeições prontas a consumir (12,2%), bebidas (9,8%). As características mais mencionadas na descrição desses produtos foram: rico em compostos bioativos (34,2%), sem glúten / sem lactose ou com baixo teor de açúcar / gordura (19,0%), saudável (11,4%) e vegetariano / vegano (11,4 %). CONCLUSÕES: Este estudo proporciona informação útil para os participantes nas futuras edições desta competição, assim como uma fonte de inspiração para empreendedores desenvolvam novos produtos alimentares.

ABSTRACT INTRODUCTION: The food sector is considered worldwide as one of the main business sectors, being constantly changing and facing multiple challenges. OBJECTIVES: This paper aims to describe the finalist teams and products in the competition for the Ecotrophelia Portugal (2017- 2020) as sources of innovation for the food sector. METHODOLOGY: A content analysis approach was adopted. The analyzed contents were collected through the official website of Ecotrophelia Portugal. Information from the 41 finalist teams in the competition between 2017 and 2020 was analyzed. RESULTS: In general, most of the finalists were female (2017 edition), belonging to the North region (57.4%), followed by the Centro region (27.9%) and Lisbon (13.1%), with the Universidade do Porto (26.2%), Universidade Católica Portuguesa (Porto: 16.4%) and the Instituto Politécnico de Coimbra (13.1%) being the main institutions from which the finalists came. The main categories to which the finalist products belonged were: snacks (34.1%), desserts (17.1%), ready-to-eat meals (12.2%), drinks (9.8%). The characteristics most mentioned in the description of these products were that they are: rich in bioactive compounds (34.2%), gluten / lactose free or low in sugar / fat (19.0%), healthy (11.4%) and vegetarian / vegan (11.4%). CONCLUSIONS: This study provides useful information for future competitors to new editions of this competition, as well as a source of inspiration for the development of new food products by entrepreneurs.