ABSTRACT The present study aimed to assess the precision of oxygen uptake with heart rate regression during treadmill running in highly trained runners. Twenty national and international level male runners were divided into two equal groups. Group A was formed of 10 sprinters (31.5± 4.7 years, height 1.74± 0.04 m and mass 61.8± 5.2 kg), and group B comprised 10 endurance runners (25.7± 4.5 years, height 1.77± 0.08 m and mass 71.2± 5.8 kg). Each participant performed six min bouts at a constant velocity on a level treadmill, with each bout at an increased running velocity. The starting velocity was 3.33 m·s-1, with a 0.56 m·s-1 increase in each subsequent bout. VO2 and HR were measured during all runs. Mean peak VO2 and mean peak HR for Group A were, respectively, 71.7± 7.0 mL·kg-1·min-1 and 179.8± 12.7 beats·min-1, while for Group B were 67.3± 4.9 mL·kg-1·min-1 and 198.2± 9.8 beats·min-1. The linearity of the regressions between VO2 and HR in both groups was very high (R2= 0.97 and R2=0.76) with small standard errors of regression. Despite a stronger correlation in endurance-trained athletes, the results of the present study indicate that it is possible to use HR as an indicator of exercise intensity in individuals trained in both speed and longer distances.

ABSTRACT The air traffic environment is a complex system that involves several players. Between the air navigation service provider (ANPS) and the final client, many different organizations act with different purposes but are strongly interfaced. Changes and modifications in terms of technology, predefined process, or personnel are constantly needed, requiring coordination among the stakeholders. However, due to the high level of interaction between the players, any change in a complex system like the air traffic environment requires risk management. This paper demonstrates the suitability and advantages of the System-Theoretic Accident Model and Processes/Systems-Theoretic Process Analysis (STAMP/STPA) method to be applied to the risk assessment of an operational air traffic modification. The method, which had never been used on an air traffic problem in Brazil before, was applied considering the implementation of segregated simultaneous operation at the Guarulhos International Airport. The results were proven to be effective in terms of deriving useful safety requirements. From such demonstration, STAMP/STPA can be considered as a feasible alternative to the brainstorming method currently applied for risk assessment and generation of safety requirements regarding modifications in the structure of the air traffic services (ATS) in Brazil.

Resumen Los herbicidas inhibidores de la ALS en combinación con inhibidores de la ACCase pueden ser utilizados como alternativa al glifosato en el control de malezas en soya RR2/STS. En el presente estudio se evalúa la eficacia de herbicidas inhibidores de la ALS, en asociación con haloxyfop, en el control de malezas para aplicación en post-emergencia (V4) de soya RR/STS. El experimento se realiza en la campaña 2017/18 en Piracicaba, Sao Paulo (SP), Brasil. Se utiliza el cultivar BMX Garra RR2/STS y los tratamientos fueron compuestos por la aplicación de herbicidas inhibidores de la ALS en asociación con haloxyfop. El diseño experimental fue de bloques al azar, con cuatro repeticiones. Se evaluaron control y masa seca de malezas, nivel de daño en las plantas de soya y productividad. Los datos fueron sometidos al análisis de varianza y las medias de los tratamientos fueron comparados por el test de Tukey. Se observaron síntomas visuales de daño en las plantas de soja, principalmente para aplicación de nicosulfuron y nicosulfuron + cloransulam. La productividad fue mayor en todos los tratamientos con herbicidas en comparación con el control sin deshierbe manual. Las asociaciones entre herbicidas inhibidores de la ALS y haloxyfop aplicadas en post emergencia (V4) del cultivar de soya BMX Garra RR2/STS fueron eficaces en el control de malezas.

Abstract It is believed that ALS inhibitor herbicides in combination with ACCase inhibitors can be used as an alternative to glyphosate in weed control in RR2/STS soybeans. In the present study, the efficacy of ALS inhibitor herbicides, in combination with haloxyfop, is evaluated in the control of weeds for post- emergence application (V4) of RR/STS soybeans. The experiment is carried out in the 2017/18 season in Piracicaba, Sao Paulo (SP), Brazil. The cultivar BMX Garra RR2/STS is used, and the treatments were composed by the application of ALS inhibitor herbicides in association with haloxyfop. The experimental design was a randomized block with four replications. Were evaluated control and dry mass of weeds, symptoms of injury in soybean plants and yield. The data were submitted to analysis of variance and the means of the treatments were compared by the Tukey test. Visual symptoms of injury were observed in soybean plants, mainly for the application of nicosulfuron and nicosulfuron + cloransulam. Soybean yield was higher in all herbicide treatments compared to the control without weeding. Associations between ALS inhibitor herbicides and haloxyfop applied post-emergence (V4) of soybean cultivar BMX Garra RR2/ STS were effective in weed control.

Abstrac The aim of the present study was to evaluate the cyclic fatigue, torsional resistance and surface roughness of Reciproc R25 instruments in four different situations, namely as new instruments and as instruments tested after clinical preparation of one, two or three maxillary molars with four root canals. The total time required to perform each root canal preparation was recorded. Cyclic fatigue resistance was determined by the time to fracture using a customized testing device (n = 10 per group). The torsional test evaluated the torque and angle of rotation to failure according to ISO 3630-1 (n = 10 per group). The roughness of the working parts of new and used instruments was evaluated with a profilometer (n = 5 per group). Statistical analysis was performed using one-way ANOVA and Tukey’s test. The level of significance was set at 5%. No fractures or deformations were observed after clinical use. Higher preparation time was needed during the third use of the instruments for all root canals (p < 0.05). There were no significant differences among the groups in regard to either cyclic fatigue or torsional resistance (p > 0.05). Regarding the roughness measurements, groove depth was higher on new and one- versus two- or three-maxillary-molar-prepared instruments (p < 0.05). It can be concluded that the clinical use of Reciproc instruments increased preparation time and decreased surface roughness. However, clinical use did not affect the cyclic fatigue or torsional resistance of the Reciproc instruments.

RESUMO Este trabalho tem como objetivo investigar o aumento da temperatura em chapas de aço inoxidável AISI 430 durante o ensaio de tração para as seguintes taxas de deformação: 0,001; 0,01 e 0,1 s-1. Para registrar a evolução da temperatura até a fratura dos corpos de prova, foi utilizada uma termocâmera por infravermelho. Os resultados obtidos pela técnica da termografia por infravermelho mostraram um aumento gradual e uniforme da temperatura durante o encruamento do material e uma elevação drástica da temperatura nas regiões de estricção e fratura dos corpos de prova. Para a taxa de deformação de 0,1 s-1 foi observado o maior gradiente de temperatura entre a estricção localizada e a fratura (110 ºC).

ABSTRACT This study aims to correlate the temperature increase induced by the strain rate of AISI 430 stainless steel sheets during the tensile test and considering the following strain rates: 0.001; 0.01 and 0.1 s-1. In order to record the evolution of the temperature until the fracture of the specimens, an infrared thermographic camera was used. The results of infrared thermography showed a gradual and uniform increase in temperature during the work hardening of the material and a drastic temperature elevation in the regions of localized necking and fracture of the specimens. For the deformation rate of 0.1 s-1 the highest temperature gradient between localized necking and fracture was observed (110 ºC).

Biodiesel made from oils is rich in polyunsaturated fatty acids methyl esters, and, consequently, presents high tendency to oxidize. Biodiesel made from fats, on the other hand, is mainly comprised by saturated chains. Although it is highly stable, they easily crystalize at low temperatures. Blends from both can exhibit optimized properties. In this work, oxidative stability, expressed by induction period (IP), and cold filter plugging point (CFPP) of blends from palm, palm kernel, babassu, tallow or lard biodiesels with soy one were measured. Biodiesel samples were prepared by two steps transesterification methodology with KOH catalysis followed by H2SO4. IP increases, as the fat biodiesel content in the blend is higher, as expected. Blends comprised by 60% of fat biodiesel by volume had their IP increased from 1.5 (lard) to 2 times (palm kernel), compared to soy one. At this level, IP was found 8 h or higher, except for palm, which 80% was required. CFPP was observed at 8 °C or lower for the blends containing up to 60% of all the fat biodiesel, except for the palm one, which a 20% content must not be surpassed. Palm kernel 80% biodiesel blend reached the Brazilian specification, that is, IP higher than 12 h and CFPP lower than 5 °C.

Resumo Objetivo: Avaliar o efeito da transição de um modelo de laudos em radiologia realizados por radiologistas gerais para um modelo relatado por subespecialização no tempo de resposta de relatórios (TAT) em radiologia e produtividade em um departamento de radiologia em um país em desenvolvimento. Materiais e Métodos: O fluxo em nosso departamento foi modificado de um sistema de relatórios gerais (qualquer radiologista lauda exames de imagem de qualquer especialidade) para um sistema de subespecialização (radiologistas laudam exclusivamente exames de imagem pertencente a sua subespecialidade - abdominal, musculoesquelético, cardiotorácico, emergência e neurologia). Este estudo retrospectivo avaliou a TAT, TAT-2 horas e TAT-24 horas e a produtividade num período de 24 meses de relatórios gerais (2015-2016) comparado a um período de 24 meses do sistema de subespecialização (2017-2018). Resultados: No total, 208.516 laudos foram gerados. A TAT reportada reduziu de uma média de 49,1-52,9 horas durante o período geral para 15,2-16,1 horas durante o período de relatórios por subespecialidade (p < 0,001). TAT-2 horas e TAT- 24 horas aumentaram significativamente de 7,9-8,7% para 52,0-61,3% e de 12,1-14,1% para 74,3-78,7%, respectivamente (p < 0.001). O número total de exames aumentou em 33% (p = 0.001) comparando os dois períodos. Conclusão: A implementação de um sistema de laudos por subespecialidade aumentou o TAT em radiologia, incluindo benefícios no TAT-2 horas e TAT-24 horas durante um período de aumento da produtividade.

Abstract Objective: To evaluate the effect that transitioning from a model of general radiology reporting to one of subspecialized radiology reporting has on report turnaround times (TATs) and on productivity in the radiology department of a hospital in a middle-income country. Materials and Methods: The reporting workflow in our radiology department was changed from general reporting (any radiologist reporting imaging studies for any specialty) to subspecialized reporting (radiologists exclusively reporting imaging studies that fall within their subspecialty-abdominal, musculoskeletal, cardiothoracic, emergency, or neurological imaging). This was a retrospective study in which we compared general reporting with subspecialized reporting in terms of the following variables: the TAT; the proportions of reports completed within 2 h and within 24 h (TAT-2h and TAT- 24 h, respectively); and productivity. Data were collected over two 24-month periods (2015-2016 for general reporting and 2017-2018 for subspecialized reporting). Results: A total of 208,516 reports were generated. The median report TAT decreased from 49.1 h and 52.9 h in 2015 and 2016, respectively, to 16.1 h and 15.2 h in 2017 and 2018, respectively (p < 0.001). The TAT-2h also improved, increasing from 8.7% and 7.9% in 2015 and 2016, respectively, to 52.0% and 61.3% in 2017 and 2018, respectively (p < 0.001), as did the TAT- 24 h, which increased from 12.1% and 14.1% in 2015 and 2016, respectively, to 74.3% and 78.7% in 2017 and 2018, respectively (p < 0.001). Between the two periods, the total number of scans performed increased by 33% (p = 0.001). Conclusion: The implementation of a subspecialized reporting system significantly improved the median TAT for radiology reports, as well as increasing the TAT-2h and TAT- 24 h, during a time of increased productivity.

RESUMO O manejo químico é o mais adotado para o controle de plantas daninhas na cultura da cana-de-açúcar. Entre as espécies de difícil controle está a tiririca (Cyperus rotundus L.). Os herbicidas utilizados precisam ser absorvidos e transportados para a cadeia de tubérculos em quantidades suficientes para serem eficazes. Assim, objetivou-se com este estudo avaliar a eficácia dos herbicidas sulfentrazona, diclosulam, imazapique, imazapir, halossulfurom, etoxissulfurom, metano arseniato ácido monossodico (MSMA) e ácido diclorofenoxiacético (2,4-D) no controle de C. rotundus e na redução da viabilidade de seus tubérculos. O experimento foi realizado em casa de vegetação, em delineamento inteiramente randomizado, com nove tratamentos e quatro repetições. Os herbicidas sulfentrazone (800 g ingrediente ativo – i.a.·ha-1), diclosulam (193,17 g i.a.·ha-1), imazapique (133 g i.a.·ha-1) e imazapir (500 g equivalente – e.a.·ha-1) foram aplicados cinco dias após o plantio dos tubérculos em pré-emergência, enquanto que o halossulfurom (112,5 g i.a.·ha-1), etoxissulfurom (135 g i.a.·ha-1), MSMA (1.975 g i.a.·ha-1) e 2,4-D (1.340 g e.a.·ha-1) foram aplicados em pós-emergência (4 a 5 folhas). Foram feitas avaliações visuais de controle, massa seca da parte aérea, número de tubérculos e bulbos, peso de tubérculos + bulbos, número de manifestações epígeas e viabilidade de tubérculos. Aos 90 dias após a aplicação (DAA) os herbicidas diclosulam, halossulfurom e etoxissulfurom propiciaram 100% de controle da parte aérea. Todos os herbicidas reduziram o número de bulbos, peso de tubérculos + bulbos e massa seca da parte aérea. Sulfentrazona, imazapic, halossulfurom, etoxissulfurom e MSMA foram os herbicidas que mais reduziram a viabilidade dos tubérculos.

ABSTRACT Chemical management is the most widely adopted technique to control weeds in sugarcane crops. Purple nutsedge (Cyperus rotundus L.) is among the most difficult species to control. Herbicides need to be absorbed and translocated in a sufficient amount for the tuber chain to be effective. Thus, this study aimed to evaluate the effectiveness of the herbicides sulfentrazone, diclosulam, imazapic, imazapyr, halosulfuron, ethoxysulfuron, monosodium methyl arsenate (MSMA), and 2,4-dichlorophenoxyacetic acid (2,4-D) in controlling C. rotundus and reducing the viability of its tubers. The experiment was carried out in a greenhouse in a completely randomized design, with nine treatments and four replications. The herbicides sulfentrazone (800 g active ingredient – ai·ha?1), diclosulam (193.17 g ai·ha?1), imazapic (133 g ai·ha?1), and imazapyr (500 g acid equivalent – ae·ha?1) were applied in preemergence at five days after planting the tubers, while halosulfuron (112.5 g ai·ha?1), ethoxysulfuron (135 g ai·ha?1), MSMA (1,975 g ai·ha?1), and 2,4-D (1,340 g ae·ha?1) were applied in postemergence (4 to 5 leaves). The parameters visual control, shoot dry matter, number of tubers and bulbs, weight of tubers + bulbs, number of epigeal manifestations, and tuber viability were analyzed. The herbicides diclosulam, halosulfuron, and ethoxysulfuron provided 100% control of the shoot at 90 days after application (DAA). All herbicides reduced the number of bulbs, weight of tubers + bulbs, and shoot dry matter. The herbicides sulfentrazone, imazapic, halosulfuron, ethoxysulfuron, and MSMA provided the highest reduction in tuber viability.

Resumo A coleta de afluentes e o manejo de águas pluviais são canalizadas em sistemas distintos, não devendo haver comunicação entre si, pois quando isto acontece é comum identificar alterações nos indicadores de qualidade dos efluentes nas estações de tratamento de esgotos. Deste modo, objetiva-se quantificar as alterações causadas pela chuva no tratamento de esgoto sanitário, os quais utilizam o sistema de lodo ativado. Para uma ETE, localizada no município de Paulista, PE, com capacidade de 400 L s-1, utilizando sistemas de lodos ativados, foram analisadas as alterações, na entrada e na saída do sistema para os: pH, temperatura, DBO e eficiência de tratamento, além da vazão de entrada, entre dias considerados secos e chuvosos. Foi constatado que o volume de entrada é incrementado em média de 25% da vazão de projeto de dimensionamento da estação. Com isto, alguns controles operacionais relevantes foram identificados, como a paralização temporária de estações elevatórias de esgoto, visando manter o pleno funcionamento do sistema, evitando sua sobrecarga. O pH sofre leve aumento na alcalinidade, cerca de 0,3, mas sem interferir no processo de tratamento. Já a temperatura do afluente em dias chuvosos sofre redução de 3 a 5K, dependendo do evento. Utilizando os testes T e Z, foi possível identificar que não houve alterações significativas (uneq. var. t: 1.18 > 0.26 e uneq var. z: 0.71 > 0.48, respectivamente) nas concentrações de DBO, tanto no efluente quanto no afluente, e a eficiência de remoção de carga orgânica foi mantida, ao contrário do que se espera em outros tipos de tratamento mais simples.

Abstract Effluent collection and stormwater management make use of different drainage systems, which should remain unconnected with one another. If stormwater drains into sewage collection systems, it often causes changes in effluent quality indicators at sewage treatment plants. This study sought to quantify the changes caused by rain in a Wastewater Treatment Plant (WWTP) located in Paulista, PE, which uses the activated sludge system. Accordingly, changes in pH, temperature, BOD, and treatment efficiency at the inlet and outlet, as well as inlet flow were analyzed on dry and rainy days at the plant, which has a sewage capacity of 400 L s-1. The input volume was found to be greater than the design flow of the station, about 25%. With this, some relevant operational controls were identified, such as temporarily shutting down sewage pumping stations in order to maintain full operation of the system and avoid overload. The pH increases slightly in alkalinity, about 0.3, but this does not interfere with the treatment process. The temperature of the influent on rainy days is about 3 to 5 degrees cooler, depending on the intensity of the event. Using the T and Z tests, it was possible to identify that BOD concentrations in the influent and the effluent were not significantly different (uneq. var. t: 1.18 > 0.26 and uneq var. z: 0.71 > 0.48, respectively), and the organic load removal efficiency was maintained, contrary to what is expected with other, more simple types of treatment.

Abstract Amyloidosis is a disease caused by extracellular deposition of insoluble protein fibrils, that results in changes in tissue architecture and consequently modification of the organ structure. Cardiac involvement is common in amyloidosis. Two major types of systemic amyloidosis affect the myocardium - immunoglobulin light chain and transthyretin amyloidosis - each leading to different prognosis. Early detection and diagnosis of cardiac amyloidosis are the main objectives in the assessment of the disease. New techniques of magnetic resonance imaging have minimized the need for biopsies for the diagnosis. Late gadolinium enhancement technique, and more recently T1 mapping, have allowed a simplified evaluation of amyloid deposits and extracellular volume. The aim of this review was to describe basic concepts and updates of the use of magnetic resonance imaging for the diagnosis amyloidosis and evaluation of its severity.

Resumo A cardiomiopatia hipertrófica (CMH) é a doença genética cardiovascular mais comum e representa a principal causa de morte súbita em pacientes jovens. A Ressonância Magnética Cardíaca (RMC) e a Tomografia Computadorizada Cardíaca (TCC) são métodos de imagem não invasivos de alta sensibilidade e especificidade, úteis no diagnóstico e no estabelecimento do prognóstico de CMH, e no rastreamento de indivíduos com fenótipos subclínicos. O aperfeiçoamento da análise da RMC e TCC tem grande potencial para promover intervenções com o objetivo de impedir o curso natural da doença. O presente estudo tem por objetivo descrever o papel da RMC e TCC no diagnóstico e prognóstico da CMH, e como essas ferramentas podem auxiliar no manejo clínico de pacientes portadores dessa doença.

Abstract Hypertrophic cardiomyopathy (HCM) is the most common genetic cardiovascular disease and represents the main cause of sudden death in young patients. Cardiac magnetic resonance (CMR) and cardiac computed tomography (CCT) are noninvasive imaging methods with high sensitivity and specificity, useful for the establishment of diagnosis and prognosis of HCM, and for the screening of patients with subclinical phenotypes. The improvement of image analysis by CMR and CCT offers the potential to promote interventions aiming at stopping the natural course of the disease. This study aims to describe the role of RCM and CCT in the diagnosis and prognosis of HCM, and how these methods can be used in the management of these patients.