Resumen: Antecedentes: Las especies exóticas invasoras exhiben diferentes rasgos ecológicos que les confieren ventajas competitivas sobre la vegetación nativa con importantes efectos en la biodiversidad. Preguntas: ¿Cuál es el riesgo de invasión de Cucurbita ficifolia Bouché teniendo en cuenta sus rasgos ecológicos y los impactos que puede estar generando en relictos boscosos? Sitio y periodo de estudio: la investigación se desarrolló durante 2021 en la Reserva Forestal Thomas van der Hammen y su área de influencia, Bogotá D.C., Colombia. Métodos: se examinaron diferentes rasgos ecológicos de C. ficifolia mediante experimentos en campo y de laboratorio. Se analizaron los impactos ecosistémicos a través de un análisis multitemporal con imágenes satelitales y con la caracterización de la vegetación y los principales órdenes de insectos polinizadores. Esta información se utilizó para evaluar su riesgo de invasión. Resultados: C. ficifolia se propagó de manera sexual, su tiempo generacional fue menor a un año. Denotó alta variabilidad morfológica en frutos y semillas registrando, además, abundante producción de semillas con alta viabilidad (> 70 %). Los puntos de contracción del bosque se correlacionaron con la dominancia de C. ficifolia, generando cambios significativos en la composición y estructura de la vegetación y en algunos procesos ecosistémicos. C. ficifolia fue calificada con un alto riesgo de invasión. Conclusiones: C. ficifolia reúne varios rasgos ecológicos asociados con una alta invasividad, lo que permitió establecerse exitosamente en relictos boscosos con efectos relevantes sobre el ecosistema.

Abstract: Background: Invasive exotic species exhibit different ecological traits that confer them competitive advantages over native vegetation, causing significant impacts on biodiversity. Questions: What is the invasion risk of Cucurbita ficifolia Bouché, considering its ecological traits and the potential impacts it may be causing in forest remnants? Study site and dates: The research was conducted in 2021 at the Reserva Forestal Thomas van der Hammen and its surrounding area, Bogotá D.C., Colombia. Methods: Various ecological traits of C. ficifolia were examined through field and laboratory experiments. Ecosystem impacts were analyzed through a multi-temporal analysis using satellite imagery and with the characterization of vegetation and key orders of pollinating insects. This information was utilized to assess its invasion risk. Results: Propagation of C. ficifolia occurred through sexual reproduction, with a generational time of less than one year. The C. ficifolia showed abundant seed production (> 70 % viable), high morphological variability in its fruits and seeds. The dominance of C. ficifolia correlated with forest contraction points, leading to significant changes in vegetation composition and structure, and some ecosystem processes. C. ficifolia was rated as having a high invasion risk. Conclusions: C. ficifolia exhibits multiple ecological traits that are linked to high invasiveness, allowing it to successfully establish itself in forest remnants with relevant effects on the ecosystem.

RESUMEN Introducción: La artropatía hemofílica (AH) cursa con diferentes manifestaciones clínicas importantes, como son las hemorragias articulares, el dolor, la disminución de la amplitud del movimiento y las alteraciones funcionales que pueden causar secuelas en la funciona lidad y movilidad. El ejercicio físico adaptado a los pacientes con hemofilia puede ser una adecuada estrategia terapéutica, que repercuta positivamente sobre la calidad de vida de dichos sujetos. Objetivos: Evaluar la eficacia de la rehabilitación física en el tratamiento de la artropatía hemofílica. Materiales y métodos: Se ha realizado una revisión sistemática y metaánálisis de ensayos clí nicos (seleccionados según criterios de elegibilidad). Para ello, se han utilizado las siguientes bases de datos: PEDro, Pubmed, Scopus y Web of Science. Se empleó la escala «PEDro» para evaluar la calidad metodológica de los estudios. Resultados: Tras aplicar los criterios de inclusión y exclusión, en la revisión final fueron incluidos siete artículos, los cuales aportaron resultados favorables sobre la fuerza y el diá metro muscular, el rango de movilidad, el estado articular y la calidad de vida. De ellos, dos estudios aportaron datos para metaanálisis, con resultados favorables sobre la variable dolor [Diferencia de medias estandarizada (DME) = -2,64; IC 95%: (-4,26; 1,03)]. Conclusiones: Se encontró evidencia sobre la eficacia de la rehabilitación física en el trata miento de la artropatía hemofílica. El ejercicio terapéutico (ET) es el principal tratamiento realizado; con este se obtuvieron mejoras significativas en distintas variables físicas.

ABSTRACT Introduction: Haemophilic arthropathy presents with different important clinical disorders, such as joint disease, pain, decreased range of motion, and functional alterations that can produce limitations in functionality and mobility. The physical exercise adapted to patients with haemophilia can be an adequate therapeutic strategy, having a positive impact on the quality of life of these subjects. Objectives: To identify the published clinical trials that evaluate the efficacy of physical rehabilitation in the treatment of haemophilic arthropathy. Materials and methods: A systematic review and meta-analysis of clinical trials was con ducted (using pre-defined eligibility criteria). The literature search was performed in the databases: PEDro, Pubmed, Scopus, and Web of Science. The quality of the methods used in the studies was evaluated using the PEDro scale. Results: After applying the inclusion and exclusion criteria, 7 studies were included in this review, providing favourable results on muscle strength and circumference, range of motion, joint disease, and quality of life. Moreover, 2 articles contributed information to the meta-analysis, showing favourable results on pain [Standardised mean difference (SMD) = -2.64; 95% CI: (-4.26; 1.03)]. Conclusions: This systematic review found evidence on the efficacy of physical rehabilitation in the treatment for haemophilic arthropathy. Therapeutic exercise is the main treatment carried out, obtaining significant improvements in the different physical outcomes.

Abstract: We estimate the impact of rural-urban migration from the period 2010-2015 on informality in metropolitan areas of Mexico. The estimation of ordinary least squares does not establish any effect, while the estimation with instrumental variables finds that exogenous rural urban migration increases informality. Other variables such as unemployment, labour participation and inequality are unaffected, indicating that informal sector allows to absorb changes in labour supply in the short term, albeit with possible negative effects on labour income of substitute workers.

Resumen: Se estima el impacto de la migración rural urbana del período 2010-2015 en la informalidad de las zonas metropolitanas de México. La estimación de mínimos cuadrados ordinarios no establece ningún efecto, mientras que la estimación con variables instrumentales encuentra que la migración rural urbana exógena incrementa la informalidad. Otras variables como el desempleo, la participación laboral y la desigualdad no son afectadas, lo que indica que el sector informal permite absorber las variaciones de la oferta laboral en el corto plazo, aunque con posibles efectos negativos sobre los ingresos laborales de los trabajadores sustitutos de los migrantes rurales.

ABSTRACT Although ethnobotanical knowledge is considered potentially valuable information for several human disciplines, it is currently declining due to a decrease in the transmission of cultural knowledge and the depletion of natural resources. Consequently, focused efforts are required to compile such information and ultimately facilitate its diffusion. Bogotá D.C. consists of a large territory of rural and urban zones which has become a place of diverse cultural dynamics due to complex processes of historical evolution, making it an important target to conserve ethnobotanical knowledge. Here, we made a thorough compilation of ethnobotanical data for Bogotá focusing on plant common names and developed a freely available online tool (Platform of Plant Common Names of Bogotá) with the aim of preserving and promoting the transmission of biocultural heritage. The compiled dataset consists of over 2,226 combinations between scientific and common names which may be queried using the online tool, leading to specific pages that display several additional features. Since its launch, the online tool has been visited over 6200 times, mainly by Colombian users under the age of 34, which is conveniently in line with our goal of improving the intergenerational transmission of biocultural heritage.

In the last 2 decades, there have been significant advances in medical treatment of heart failure. However, there is a group of patients who are refractory to the available medical therapy and progress inevitably to a state of end-stage heart failure, whose only therapeutic alternative is cardiac transplantation. But this is an option limited by the scarce availability of donors. Therefore many patients die waiting for an organ. Recently, extra or intracorporeal left ventricular devices have emerged as a viable alternative for patients with end-stage heart failure waiting for a heart transplant. These devices discharge the left ventricle, increasing cardiac output and improving systemic perfusion. This year, in our hospital we began a left ventricular device implantation program for the most severely ill patients on the waiting list for cardiac transplantation. We report two males aged 30 and 53 years, in whom a left ventricular device was successfully implanted, using a minimally invasive surgical technique developed at the University of Hannover in Germany.

Under laboratory conditions of 27 ± 2 °C, 80 ± 5% R. H. and 12:12 L:D, we performed a characterization of 16 strains of the entomopathogenic fungus Beauveria bassiana (Bals.) Vuillemin, through bioessays by immersion. The strains were isolated from different hosts and their pathogenicity was evaluated on Ceratitis capitata (Wiedemann) females. Results showed that mortality of flies ranged from 9.1 to 91.9%. Average lethal time (LT50) of the most pathogenic strain was 3.8 days; while that the less pathogenic strain took 17.6 days. In a second series of experiments, the strains that registered the highest biological activity were evaluated as mentioned above. These strains showed high levels of mortality, spore production and spore recovery from the infected insects. According with these results, we discuss the potential that five strains of B. bassiana have be tested under field conditions to determinate if can be used in the control of this pest.

Bajo condiciones de laboratorio (27 ± 2 °C de temperatura, 80 ± 5% de H. R. y 12:12 horas luz: obscuridad), se caracterizaron mediante bioensayos por inmersión, la patogenicidad de 16 cepas del hongo Beauveria bassiana (Bals.) Vuillemin aisladas de diferentes hospederos sobre hembras de Ceratitis capitata (Wiedemann). El rango de mortalidad que se observó fue de 9.1 a 91.9%; el tiempo letal medio de la cepa más virulenta fue de (TL50 = 3.83 días), mientras que en la cepa con menor virulencia, el tiempo letal medio fue de (TL50 = 17.64 días). En una segunda fase, las cepas que registraron mayor actividad biológica fueron evaluadas mediante el mismo procedimiento, en donde se registraron elevados índices de mortalidad, producción y recuperación de conidios a partir de los insectos infectados. De acuerdo con estos resultados, se discute el potencial que cinco cepas de B. bassiana tienen para ser evaluadas en condiciones de campo y determinar si pueden ser utilizadas en el control de dicha plaga.