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O Condicionamento Farmacológico pode ser Resgatado pela Dexmedetodina: Como um Sedativo pode Mitigar Lesões de I/R? Dexmedetodina I/R IR I R
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Maciel, Leonardo

Arquivos Brasileiros de Cardiologia

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2023, Volume 120 Nº 10 elocation e20230696

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

https://doi.org/10.36660/abc.20230696

Small scale market survey on the preparation and physico-chemical characterstics of moin-moin: a traditional ready-to-eat cowpea food from Brazil
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CARDOSO, Lafaiete Almeida

; GREINER, Ralf

; SILVA, Cíntia de Santana

; MACIEL, Leonardo Fonseca

; SANTOS, Luis Fernandes Pereira

; ALMEIDA, Deusdélia Teixeira de

Food Science and Technology

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2022, Volume 42 elocation e59920

Resumo: En | Texto: En | PDF: En

Abstract Preparation practices and physicochemical characteristics of moin-moin commercialized in Salvador (Brazil) as a street food by typically clothed women called baianas de acarajé were studied. Four moin-moin samples were collected from each of the thirty sales points included in the study and analyzed for moisture, protein, fat, ash, carbohydrates, fiber, total carotenoids, weight, color and texture. The ingredients used for the preparation of moin-moin were as follows: grated dry shrimp heads (100.0%), grated onions (96.7%), salt (73.3%), Crude Palm Oil (53.3%) or Crude Palm Olein (46.7%) and garlic (16.7%). Peanut, codfish, cashew nuts, wheat flour, ginger and tomatoes are further ingredients frequently used. Texture analysis revealed that moin-moin is a soft, fragile and brittle food product. The content of total carotenoids ranged from 6.99 to 64.88 ppm with an average value of 28.49 ± 4.00 ppm, giving the product an ocher-orange/yellow-orange color. An average sized moin-moin ball (186.6 g) contained 14.08% protein, 13.08% lipids, 30.83% carbohydrates, 4.01% fiber and 297.42 kcal, corresponding to 18.77%, 23.78%, 10.28% and 14.87% of the daily requirements of an adult for protein, lipids, carbohydrates and energy, respectively.

https://doi.org/10.1590/fst.59920

Chemical composition and fatty acids profile of chocolates produced with different cocoa (Theobroma cacao L.) cultivars
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MELO, Calionara Waleska Barbosa de

; Bandeira, Matheus de Jesus

; MACIEL, Leonardo Fonseca

; BISPO, Eliete da Silva

; SOUZA, Carolina Oliveira de

; SOARES, Sérgio Eduardo

Food Science and Technology

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Jun 2020, Volume 40 Nº 2 Páginas 326 - 333

Resumo: En | Texto: En | PDF: En

Abstract The objective of the present study was to characterize the physicochemical composition and to quantify the fatty acids of chocolates produced from different cocoa varieties (Theobroma cacao L.) cultivated in the Southern Region of Bahia. Nine samples of monovarietal chocolates were evaluated, according to their physical, thermal and fatty acid profile. The results were subjected to tests of variance and multivariate statistics. The chocolates PH16 and TSH1188 presented higher melting point. It was possible to identify a linear correlation between the fat content of the chocolates and the break force parameter. The chocolates showed higher concentration of saturated fatty acids, mainly palmitic acid (16:0) and stearic acid (18:0), followed by the unsaturated fatty acids among which oleic acid (18:1n-9) and linoleic acid (18:6) were predominant. The principal component analysis allowed to discriminate the different varieties of chocolate according to the profile of fatty acids. The thermogravimetric analysis of the samples showed a similar profile. The differences found in the samples of chocolates were attributed to factors such as the fruit maturation process, the cocoa variety and to which they were subjected during processing.

https://doi.org/10.1590/fst.43018 3691 downloads

Leprosy: clinical and epidemiological study in patients above 60 years in Espírito Santo State - Brazil
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Diniz, Lucia Martins

; Maciel, Leonardo Bezerra

Anais Brasileiros de Dermatologia

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Dez 2018, Volume 93 Nº 6 Páginas 824 - 828

Resumo: En | Texto: En | PDF: En

Abstract: Background: Leprosy is a chronic infectious disease that is endemic in Brazil and little studied in patients over 60 years old. Objective: The aim of this study was the epidemiological and clinical description of cases of leprosy in individuals older than 60 years, notified in the State of Espírito Santo - Brazil. Methods: It was an observational, descriptive and retrospective study of leprosy patients notified between 2001 and 2011. Results: Out of 16,025 notifications, 2,510 (15.6%) were of patients over 60 years of age; the distribution among the period was egalitarian except in the last 2 years, when there was a mild reduction of cases; the average was 70 years of age (±7 years); 46% were women, being 62% of those paucibacillary cases; 1,145 (50.5%) were dark-skined people in particular among paucibacillary cases; 1,638 (72.9%) were illiterates or poorly instructed n particular among multibacillary cases (P=0.022); 59.9% patients were clinically multibacillary cases and 37.4% had positive bacilloscopy; 37.9% patients had clinical alterations on peripheral nerves, 36.7% of all the multibacillary cases were classified as grade I and 15.3% as grade in assessment of disability. Study limitations: This was a retrospective study, which used secondary data generated by physicians and notified by other professionals, whar could have enabled possible errors on original data. Conclusions: Leprosy in this age group suggests a long incubation period with reactivation of latent focus or late infection. Men were more affected, as well as the afro descendent race was statistically significant in the paucibacillary cases (P=0.000) and illiterate/poor education in multibacillary cases (P=0.022). Nearly 40% of patients had positive bacilloscopy and grade I/II disability, demonstrating a late diagnosis.

https://doi.org/10.1590/abd1806-4841.20187092 906 downloads

Influence of drying methods on cocoa (Theobroma cacao L.): antioxidant activity and presence of ochratoxin A
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DEUS, Valterney Lima

; CERQUEIRA E SILVA, Mariana Barros de

; MACIEL, Leonardo Fonseca

; MIRANDA, Lucas Caldeirão Rodrigues

; HIROOKA, Elisa Yoko

; SOARES, Sérgio Eduardo

; FERREIRA, Ederlan de Souza

; BISPO, Eliete da Silva

Food Science and Technology

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Dez 2018, Volume 38 Páginas 278 - 285

Resumo: En | Texto: En | PDF: En

Abstract This work aimed to evaluate the performance of different drying methods in the development of phenolic compounds, methylxanthines, and antioxidant activity in cocoa bean and to evaluate the presence of ochratoxin A (OTA). Antioxidant activity was determined using DPPH, FRAP, ORAC and β-carotene-linoleic acid assays. Phenolic compounds and methylxanthines were determined using high-performance liquid chromatography with an ultraviolet detector (HPLC-UV). OTA was determined by ultra-performance liquid chromatography with fluorescence detection (UPLC-FLR). It was found that during cocoa drying, there was a reduction in antioxidant activity with reduced phenolic compound content (0.04 mg.g-1 of catechin before drying to 0.02 mg.g-1 after drying) and reduced methylxanthines (19.44 mg.g -1 of theobromine before drying to 11.71 mg.g-1 after drying). Only one sample showed contamination by OTA (7.1 μg.kg-1). The traditional drying method showed the highest conservation of antioxidant activity and methylxanthine and phenolic compound content.

https://doi.org/10.1590/fst.09917 5308 downloads

Eco-epidemiologic study of emerging fungi related to the work of babaçu coconut breakers in the State of Maranhão, Brazil
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Nascimento, Maria do Desterro Soares Brandão

; Leitão, Valéria Maria Sousa

; Silva, Marcos Antonio Custódio Neto da

; Maciel, Leonardo Bezerra

; Muniz Filho, Walbert Edson

; Viana, Graça Maria de Castro

; Bezerra, Geusa Felipa de Barros

Revista da Sociedade Brasileira de Medicina Tropical

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Jan 2014, Volume 47 Nº 1 Páginas 74 - 78

Resumo: En | Texto: En | PDF: En

Introduction: There are more than 300,000 extractors using the babaçu coconut as a source of income in the States of Maranhão, Pará, Tocantins and Piauí, and this activity is associated with fungal infections. The objective of this study was to examine the occurrence of emergent fungi in the conjunctiva, nails and surface and subcutaneous injuries of female coconut breakers in Esperantinópolis, Maranhão. Additionally, soil samples and palm structures were collected. Methods: The obtained samples were cultured in Petri dishes containing potato-dextrose-agar and chloramphenicol. The etiological agent was confirmed by a direct mycological exam and growth in culture. Results: In total, 150 domiciles were visited, and samples were collected from 80 patients. From the ground, the most frequently isolated fungus was Aspergillus niger (53. 8%). the most frequently detected fungus in babaçu coconut was Aspergillus niger (66.7%). Conjunctival fungal growth occurred in 76.3% of the women. The ocular fungal microbiota consisted of filamentous fungi (80.6%), and yeasts were present in 19.4% of cases. Onychomycosis was diagnosed in 44% (11/25) of the women. Conclusions: The identification of the genera Neosartorya, Rhizopus and Curvularia in onychomycoses shows that emergent filamentous fungi can be isolated. Aspergillus sp., Penicillium sp. and Scedosporium sp. were the predominant genera found in the babaçu coconut. From ocular conjunctiva, Candida spp. were the most prevalent species isolated, and Fusarium sp. was present only in one woman. The nearly permanent exposure of coconut breakers to the external environment and to the soil is most likely the reason for the existence of a mycotic flora and fungal infections, varying according to the individual's practices and occupation.

https://doi.org/10.1590/0037-8682-0237-2013 2291 downloads

Pain, masticatory performance and swallowing threshold in orthodontic patients
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Trein, Marcos Porto

; Mundstock, Karina Santos

; Maciel, Leonardo

; Rachor, Jaqueline

; Gameiro, Gustavo Hauber

Dental Press Journal of Orthodontics

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Dez 2013, Volume 18 Nº 6 Páginas 117 - 123

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

OBJETIVO: o objetivo desse estudo foi avaliar a dor, a performance mastigatória e o limiar de deglutição em pacientes submetidos ao tratamento ortodôntico. MÉTODOS: foram avaliados dez pacientes de ambos os sexos (idade média 17,25 ± 5,21 anos), com dentição permanente completa, submetidos ao tratamento ortodôntico com aparelhos fixos. A performance mastigatória e o limiar de deglutição foram avaliados pela capacidade individual de fragmentação de um alimento teste artificial (Optocal), o qual foi mastigado e as partículas resultantes processadas por um método padronizado com peneiras, apresentando o tamanho mediano das partículas (TMP) das unidades trituradas. A intensidade da dor/desconforto foi avaliada com o uso de uma escala analógica visual. Todos os testes foram realizados nos seguintes momentos: T0: antes da ativação do aparelho ortodôntico; T1: 24 após a ativação, e T2: 30 dias após a ativação. RESULTADOS: os resultados demonstraram um aumento significativo na dor em T1 (T0: 0,60 ± 0,70mm; T1: 66,2 ± 34,5mm), retornando aos valores basais em T2 (3,20 ± 3,82mm). A performance mastigatória também foi reduzida em T1 (TMP: 10,15 ± 1,1mm²) comparada a T0 (TMP: 7,01 ± 2,9mm²) e T2 (TMP = 6,76 ± 1,3 mm²). Entretanto, o tamanho das partículas não foi afetado no teste do limiar de deglutição (T0: 5,47 ± 2,37mm²; T1: 6,19 ± 2,05mm²; T2: 5,94 ± 2,36mm²). CONCLUSÃO: os aparelhos ortodônticos não interferiram no tamanho das partículas que seriam deglutidas, mesmo na presença da dor.

OBJECTIVE: The aim of this study was to assess pain, masticatory performance and swallowing threshold of patients undergoing orthodontic treatment. METHODS: Ten patients of both genders (mean age of 17.25 ± 5.21 years), with complete permanent dentition, who underwent orthodontic treatment with fixed appliances were evaluated. The masticatory performance and the swallowing threshold were assessed by patient's individual capacity of fragmenting an artificial test food (Optocal) which was chewed and had the resulting particles processed by a standardized sieving method, presenting the median particle size (MPS) of crushed units. The intensity of pain / discomfort during chewing was evaluated by means of a visual analog scale. All tests were performed at the following times: T0 - before activating the orthodontic appliance; T1 - 24 hours after activation, and T2 - 30 days after activation. RESULTS: The results showed a significant increase in pain at T1 (T0 - 0.60 ± 0.70 mm; T1 - 66.2 ± 34.5 mm), returning to baseline values at T2 (3.20 ± 3.82 mm). Masticatory performance was also reduced in T1 (MPS 10.15 ± 1.1 mm²) in comparison to T0 (MPS 7.01 ± 2.9 mm²) and T2 (MPS 6.76 ± 1.3 mm²). However, particle size was not affected in the swallowing threshold test (T0 - 5.47 ± 2.37 mm²; T1 - 6.19 ± 2.05 mm²; T2 - 5.94 ± 2.36 mm²). CONCLUSION: The orthodontic appliances did not interfere in the size of the particles that would be swallowed, even in the presence of pain.

2470 downloads

Phenolic compounds, methylxanthines and antioxidant activity in cocoa mass and chocolates produced from "witch broom disease" resistant and non resistant cocoa cultivars
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Leite, Paula Bacelar

; Maciel, Leonardo Fonseca

; Opretzka, Luiza Carolina França

; Soares, Sergio Eduardo

; Bispo, Eliete da Silva

Ciência e Agrotecnologia

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Jun 2013, Volume 37 Nº 3 Páginas 244 - 250

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

A "vassoura bruxa" causada pelo fungo Moniliophthora perniciosa, é uma das doenças mais importantes do cacau na América Latina, provocando uma redução de cerca de 70% na produção das amêndoas na Bahia. Para tentar resolver o problema, muitos cultivares resistentes à enfermidade têm sido recomendados para os agricultores. Por outro lado, as características do chocolate são oriundas de várias substâncias, cuja formação depende da origem genética do fruto, do meio ambiente onde o cacau é cultivado e das operações de processamento. Assim, neste trabalho, objetivou-se determinar os compostos fenólicos monoméricos, metilxantinas e a atividade antioxidante em massa de cacau e chocolates provenientes de cultivares resistentes à "vassoura de bruxa" e não resistentes à doença. Os compostos fenólicos totais na massa de cacau não variou entre os cultivares com valores que variam entre 25,03mg g-1 a 23,95mg g-1. Chocolates feitos a partir de cultivares não resistentes à doença apresentaram maior teor de fenólicos totais (19,11mg g-1) que os cultivares resistentes, SR162 e PH16 com 16,08mg.g-1 e 15,46 mg.g-1, respectivamente. Os conteúdos de epicatequina foram superiores aos de catequina em todos os cultivares. Houve diferenças significativas entre as amostras de massa de cacau analisadas para a cafeína. Chocolates produzidos a partir do cultivar SR162 apresentaram maior quantidade de compostos fenólicos e metilxantinas. A amostra de chocolate com a atividade antioxidante mais elevada é a SR162, seguida dos cultivares não resistentes e PH16, mostrando uma relação entre a atividade antioxidante e o conteúdo de compostos fenólicos monoméricos.

The "witch broom disease" caused by the fungus called Moniliophthora perniciosa is one of the most important cocoa diseases in Latin America, causing around 70% production reduction in the southern Bahia. In attempt to solve the problem, many cultivars resistant to the disease have been recommended to farmers. On the other hand, the chocolate flavour is composed by many compounds whose formation depends on the genetic background, environment where cocoa is grown and processing operations. Therefore, this work aimed at determining the monomeric phenolic compounds, methylxanthines and antioxidant activity of cocoa mass and dark chocolate from cocoa cultivars resistant to "witch broom disease" and non resistant to the disease. The total phenolic compounds in cocoa mass did not vary among cultivars with values ranging from 23.95mg g-1 to 25.03mg g-1. Chocolates made from non resistant cultivars showed higher total phenolic compounds (19.11mg g-1) than SR162 and PH16 with 16.08mg g-1 and 15.46mg g-1, respectively. Epicatechin had higher content than catechin and the levels of these two compounds were higher in SR162. There were significant differences among samples of cocoa mass analyzed for caffeine. Chocolate made from SR162 had the highest amount of monomeric compounds due to its high concentration of catechin and epicatechin. The chocolate sample with the highest antioxidant activity was the SR162, followed by non resistant blend and PH16, showing relationship between the antioxidant activity and monomeric phenolics content.

4966 downloads

The prevalence of overweight and obesity in adolescents in Bahia, Brazil
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Ferreira Marques, Cibele Dantas

; Càssia Ribeiro Silva, Rita de

; Machado, Maria Ester C.

; Portela de Santana, Mônica Leila

; Castro de Andrade Cairo, Romilda

; Jesus Pinto, Elizabete de

; Oliveira Reis Maciel, Leonardo

; Rodrigues Silva, Luciana

Nutrición Hospitalaria

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Abr 2013, Volume 28 Nº 2 Páginas 491 - 496

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Aim: A cross-sectional study was conducted with 1,477 middle school students enrolled in the public school network in Salvador, Bahia, Brazil to assess the prevalence of overweight and obesity. Methods: The sample was determined using a two-stage cluster sampling technique for selecting schools and classes. A posteriori error was estimated. The students were classified as overweight or obese according to the World Health Organization's 2007 classifications. They were also classified according to age, stage of sexual maturity, socioeconomic class and the presence of abdominal obesity. Results: Overall, 9.3% of the students were overweight and 6.4% were obese; therefore, 15.7% of the students were considered to have excess weight (obesity + overweight), at a 95% confidence interval. Abdominal obesity was found in 12.9% of all students and in 13% of those of normal weight. An association was found between excess weight and age < 14 years (p = 0.030) and abdominal obesity (p = 0.001). Conclusions: Intervention programs should be implemented to prevent and treat obesity in childhood and adolescence. In addition, professionals working with individuals in this age group should be sensitized to this problem. The need to standardize the anthropometric indicators used in the different studies is also emphasized.

Objetivo: Un estudio transversal se llevó a cabo con 1477 estudiantes de primaria matriculados en las escuelas públicas de Salvador, Bahía, Brasil, para evaluar la prevalencia del sobrepeso y la obesidad. Métodos: La muestra se determinó por la técnica de muestreo por conglomerados en dos etapas para la selección de escuelas y clases. Más tarde, posteriori error se calculó. Los estudiantes fueron clasificados como sobrepeso u obesos de acuerdo con la clasificación de la Organización Mundial de la Salud, 2007. Ellos también fueron clasificados de acuerdo a la edad, la etapa de maduración sexual, y la presencia de obesidad abdominal. Resultados: En general, el 9,3% de los estudiantes tenían sobrepeso y el 6,4% eran obesos, por lo tanto, el 15,7% de los alumnos se considera que tienen exceso de peso (sobrepeso + obesidad), con un intervalo de confianza del 95%. De la población total estudiada el 12,9% presentaron obesidad abdominal, esta condición se observa en el 13% de su peso normal. Se encontró asociación entre el sobrepeso y la edad < 14 años (p = 0,030) y obesidad abdominal (p = 0,001). Conclusiones: Los programas de intervención deben ser implementados para prevenir y tratar la obesidad en la infancia y la adolescencia. Además, los profesionales que trabajan con las personas en este grupo de edad deben ser sensibles a este problema. La necesidad de estandarizar los indicadores antropométricos utilizados en los diferentes estudios se enfatiza también.

https://doi.org/10.3305/nh.2013.28.2.6187 620 downloads

10.

Resultados do registro de cirurgias colorretais videolaparoscópicas realizadas no Estado de Minas Gerais - Brasil de 1996 a 2009
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Queiroz, Fábio Lopes de

; Côrtes, Marcelo Giusti Werneck

; Rocha Neto, Paulo

; Alves, Adriana Cherem

; Freitas, Antônio Hilário Alves

; Lacerda Filho, Antonio

; Neiva, Augusto Motta

; Hanan, Bernardo

; Côrtes, Bruno Giusti Werneck

; Bechara, Christiane de Souza

; Maia Junior, Cleber Luiz Scheidegger

; Fernandes, Cristiane Koizimi Martos

; Mansur, Eliane Sander

; Cruz, Geraldo Magela Gomes da

; Silva, Hélio Antônio

; Mendonça, Isabela Alvarenga

; Vasconcelos, Jander Bairral

; Figueiredo, Juliano Alves

; Sena, Kanthya Arreguy de

; Maciel, Leonardo

; Costa, Luciana Pyramo

; Luz, Magda Maria Profeta da

; Santos, Marco Antônio Miranda dos

; Carmona, Maria Zuleime

; Maranhão, Ramon Pires

; Paiva, Rodrigo de Almeida

; Silva, Rodrigo Gomes da

; Leite, Sinara Mônica de Oliveira

; Oliveira, Teon Augusto de Noronha

; Silva, Thaísa Barbosa da

; Alves Filho, Valdivino

; Lamounier, Paulo Cesar de Carvalho

Revista Brasileira de Coloproctologia

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Mar 2010, Volume 30 Nº 1 Páginas 61 - 67

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

INTRODUÇÃO: A partir de 1991, a videolaparoscopia começou a ser considerada no tratamento de doenças colorretais. O aprimoramento da técnica cirúrgica associado aos benefícios encontrados em diversos estudos publicados levou a modificações nas perspectivas da videolaparoscopia. A partir da publicação do estudo COST as ressecções oncológicas laparoscópicas foram reconhecidas como alternativa viável, com resultados semelhantes à cirurgia convencional. PACIENTES E MÉTODOS: Realizou-se pesquisa através de formulário específico e consulta a prontuários dos principais serviços de coloproctologia de Belo Horizonte. Avaliando-se sexo, idade, indicação cirúrgica, procedimento realizado, técnica laparoscópica, complicações, conversão, estadiamento e recidiva (no caso de neoplasias). RESULTADOS: Foram levantados dados sobre 503 cirurgias colorretais laparoscópicas: 347 (68,9%) em mulheres e 156 (31,1%) homens. A técnica cirúrgica foi totalmente laparoscópica em 137 casos, vídeo-assistida 245 casos. O procedimento mais realizado foi a retossigmoidectomia (41,1%), seguido pela colectomia direita (12,5%), colectomia esquerda (6,9%). Doenças benignas foram responsáveis por 259 (51,5%) casos, destes as principais indicações cirúrgicas foram endometriose 126 (48,6%), pólipos 40 (15,4%), doença diverticular 30 (11,6%). Das 240 cirurgias realizadas por doenças malignas as mais frequentes foram retossigmoidectomia 102 (42,5%), colectomia direita 46 (19,1%), colectomia esquerda 18 (7,5%), amputação abdominoperineal 18 (7,5%). Houve 54 conversões (10.7%) dos casos, 12,9% (31/240) nos casos de neoplasias, 8,5% (22/259) nos de doenças benignas. Complicações sistêmicas ou cirúrgicas ocorreram em 31 (6,1%) e 56 (11,1%) casos, respectivamente. Foram registrados onze (2,18%) óbitos nos primeiros 30 dias após a cirurgia. CONCLUSÃO: O estudo atual foi o primeiro levantamento da implantação de cirurgias colorretais laparoscópicas realizado de forma multicêntrica em Minas Gerais. Os dados levantados são consistentes com registros nacionais de videocirurgia colorretal, mostrando a eficiência do método de aprendizado com realização de cirurgias com tutor. Além disso, que pequena parte das cirurgias colorretais são realizadas por via laparoscópica no estado, restritos apenas a centros especializados, sobrecarregando esses serviços e limitando o acesso para a população.

INTRODUCTION: Since 1991, laparoscopic surgery started to be considered in the treatment of colorectal disease. With the improvement of the technique and the confirmation of the benefits shown in several studies, the perspective of laparoscopy has changed. Recently, the oncologic resections were recognized as a viable alternative, with similar results to the conventional technique. PATIENTS AND METHODS: Data were collected based on charter review and a specific form from the coloproctology reference centers in Minas Gerais. The data assessed were age, gender, indication for surgery, the procedure performed, the laparoscopic technique, complications, conversion rate and staging (in case of tumor). RESULTS: Data from 503 surgeries were analyzed: 347 (68.9%) were women, and 156 (31.1%) men. The technique was totally laparoscopic in 137 cases, laparoscopically-assisted in 245. The procedure most frequently performed was rectosigmoidectomy (41.1%), followed by right hemicolectomy (12.5%) and left hemicolectomy (6.9%). Conversion occurred in 10.7% (54) cases, being 12.9% (31/240) in cases of neoplasia and 8.5% (22/259) in benign diseases. Systemic or surgical complications occurred in 31 (6.1%) and 56 (11.1%) cases, respectively. The surgical mortality was 2.18% (11). Benign diseases were responsible for 259 (51.5%) cases, the most frequent indications were endometriosis 126 (48.6%), polyps 40 (15.4%) and diverticular disease 30 (11.6%) cases. From the 240 surgeries performed for malignant disease, the most frequent were rectosigmoidectomy 102 (42.5%), right hemicolectomy 46 (19.1%), left hemicolectomy 18 (7.5%) and abdominoperineal resection 18 (7.5%). CONCLUSION: This study was the first survey about the implementation of laparoscopic colorectal surgery done in Minas Gerais. The data are consistent with the national registry of colorectal surgery.

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11.

The presence of antiautonomic membrane receptor antibodies do not correlate with brain lesions in Chagas' disease
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Py, Marco O.

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Set 2009, Volume 67 Nº 3a Páginas 633 - 638

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

A correlação entre disfunção parassimpática e lesões de substância branca cerebral em pacientes chagásicos já foi previamente demonstrada. OBJETIVO: Correlacionar a presença de anticorpos circulantes funcionais com atividade beta-adrenérgica (Ab-β), muscarínica (Ab-M) ou muscarínica e beta adrenérgica (Ab-Mβ), a presença de disautonomia e lesões de substância branca cerebral em pacientes chagásicos crônicos. MÉTODO: Em quinze pacientes chagásicos consecutivos, foram realizados a avaliação do sistema nervoso autônomo e ressonância magnética (RM) do crânio. O soro dos pacientes foi testado para a presença de anticorpos funcionais circulantes. RESULTADOS: O soro de 11 dos 15 pacientes chagásicos apresentou alguma atividade (Ab-β: 7; Ab-M: 1; Ab-Mβ: 3); porém não houve correlação significativa entre a presença de anticorpos circulantes e disautonomia ou de hiperintensidades à RM. CONCLUSÃO: O mecanismo envolvido na gênese das lesões hiperintensas à RM do crânio dos pacientes chagásicos crônicos não está esclarecida ainda, apesar de aparentemente relacionada à disfunção parassimpática.

We previously demonstrated correlation between parasympathetic dysfunction and brain white matter lesions in chronic chagasic patients. OBJECTIVE: To correlate serum functional circulating antibodies with beta adrenergic (Ab-β), muscarinic (Ab-M) or muscarinic and beta adrenergic (Ab-Mβ) activity, the autonomic system function and brain lesions in chronic chagasic patients. METHOD: In fifteen consecutive chagasic patients, the autonomic nervous system was evaluated and brain magnetic resonance imaging (MRI) was performed. The sera of all patients were tested to the presence of circulating functional antibodies. RESULTS: Sera from 11 of 15 chronic chagasic patients had some activity (Ab-β: 7; Ab-M: 1; Ab-Mβ: 3); however, there was no significant correlation between the presence of antibodies and the autonomic system function or the presence of hyperintensities in MRI. CONCLUSION: The mechanism involved in the genesis of hyperintense lesions seen in brain MRI of chronic chagasic patients is still unresolved, although apparently related to parasympathetic dysfunction.

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