ABSTRACT Sexual solicitation and sexualized interaction with minors by adults constitute one of the most pernicious risks of the Internet. Little is known about the age range in which this phenomenon is most prevalent or the relationship and overlap of this problem with other risks, such as peer-to-peer cybervictimization and cyber dating abuse. Additionally, little empirical evidence exists on whether the overlap between these types of online victimization affects health-related quality of life (HRQoL). This study aimed to: 1) analyze the prevalence of sexual solicitation and interaction according to sex and stage of adolescence; 2) relate this problem to other forms of online victimization (cybervictimization and cyber dating abuse); 3) analyze the overlap between these forms of online victimization and differences in HRQoL scores. A cross-sectional and analytical study with 3,578 adolescents (52.7% girls) aged between 10-15 years was carried out. Of the adolescents in the study sample, 12.6% (n = 448) had received sexual requests and 6.4% (n = 230) had interacted sexually with adults. Sexual solicitation was most common among girls in middle adolescence. Of the participants, 33.9% (n = 1,216) had been involved in some form of online victimization. Peer cybervictimization and cyber dating abuse were positively and significantly correlated with sexualized solicitation/interactions with adults. Victims with the overlapping of all three types of online victimization (2.7%, n = 98) presented the lowest HQRoL scores (p < .001).

RESUMEN La solicitación e interacción sexual con menores por parte de adultos constituyen uno de los riesgos más perniciosos de Internet. Se sabe poco sobre la franja de edad en el que es más frecuente o sobre la relación y el solapamiento de este problema con otros riesgos, como la cibervictimización entre iguales y el abuso online en la pareja. Además, existen pocas evidencias empíricas sobre si el solapamiento entre estos tipos de victimización afecta a la calidad de vida relacionada con la salud (CVRS). Los objetivos de este estudio fueron: 1) analizar la prevalencia de la solicitación/interacción sexual en función del sexo y la etapa de la adolescencia, 2) relacionar esta problemática con la cibervictimización entre iguales y el abuso online en la pareja, 3) analizar el solapamiento entre estas formas de victimización online y sus diferencias en las puntaciones de CVRS. Se trata de un estudio transversal y analítico con 3,578 adolescentes (52.7% chicas) entre 10-15 años. El 12.6% (n = 448) habían recibido solicitaciones sexuales y el 6.4% (n = 230) había interactuado sexualmente con adultos. La solicitación sexual fue más frecuente en chicas en la adolescencia media. Un 33.9% (n = 1,216) había sufrido algún tipo de victimización online. La cibervictimización entre iguales y el abuso online en la pareja correlacionaron positiva y significativamente con solicitaciones/interacciones sexualizadas con adultos. Las víctimas que solaparon los tres tipos de victimización online (2.7%, n = 98) presentaron las puntuaciones de CVRS más bajas (p < .001).

Resumo O objetivo deste artigo foi analisar a relação entre o conteúdo informacional dos principais assuntos de auditoria (PAA) reportados no Relatório de Auditoria Independente (RAI) e a previsão de analistas financeiros das empresas listadas na B3 S.A. - Brasil, Bolsa, Balcão (B3). As pesquisas que investigaram a relevância dos PAA não analisaram as informações incrementais sobre o auditado, na visão do auditor independente, que possam vir a afetar a previsão dos analistas financeiros. Os achados desta pesquisa evidenciam que os PAA reportados apresentam conteúdo informacional relevante sobre o auditado aos analistas financeiros, melhorando a qualidade das suas previsões. Adicionalmente, observou-se na análise quantílica que os PAA contribuem para um ajuste fino nas previsões dos analistas. Ainda, amplia-se o debate da relação auditor-analista, especificamente quanto à utilidade dos PAA para os analistas financeiros, no tocante à consideração de uso dessas informações nas suas projeções das empresas analisadas, reforçando a busca pela sua melhoria por parte do regulador. A análise foi realizada com base em regressão de mínimos quadrados generalizados [generalized least square (GLS)] e quantílica em 137 companhias não financeiras, utilizando dados de previsões (trimestrais e anuais) de analistas disponíveis na Thomson Reuters Eikon® e informações financeiras na Economatica®. De modo geral, a quantidade e o conteúdo dos itens reportados como PAA se revelaram significantes em relação à previsão do lucro por ação e ao erro das projeções dos analistas, evidenciando redução da assimetria. Assim, quanto maior o valor informativo dos PAA, melhor é a qualidade dessa informação, contribuindo para formar o consenso de previsão de lucro e minimizar o erro das estimativas dos analistas financeiros. Adicionalmente, observou-se que a divulgação dos PAA não tem reflexo imediato sobre a previsão de lucros no trimestre seguinte à sua divulgação, sendo que seu conteúdo informacional é diluído ao longo do exercício seguinte, refletindo na previsão do lucro anual.

Abstract The aim of this article was to analyze the relationship between the informational content of the key audit matters (KAMs) reported in the Independent Audit Report (IAR) and financial analysts’ forecasts for the companies listed on the B3 S.A. - Brasil, Bolsa, Balcão (B3). The research that has investigated the relevance of KAMs has not analyzed the incremental information about the audited firm, from the independent auditor’s viewpoint, that can affect financial analysts’ forecasts. The findings of this research reveal that the KAMs reported present relevant informational content about the audited firm for financial analysts, thus improving the quality of their forecasts. In addition, it was observed in the quantile analysis that the KAMs contribute to the fine tuning of analysts’ forecasts. The debate on the auditor-analyst relationship is also widened, specifically regarding the utility of KAMs for financial analysts, in terms of them considering using this information in their projections for the analyzed companies, thus reinforcing the search for their improvement by the regulator. The analysis was conducted based on generalized least squares (GLS) and quantile regressions covering 137 non-financial companies, using data from (quarterly and annual) analysts’ forecasts available from Thomson Reuters Eikon® and financial information from Economatica®. In general, the quantity and content of the items reported as KAMs were revealed to be significant in relation to the analysts’ earnings per share forecasts and to their forecasting error, revealing a reduction in asymmetry. Thus, the higher the informational value of the KAMs, the better the quality of that information is, contributing to forming an earnings forecast consensus and minimizing the error in the financial analysts’ estimates. In addition, it was observed that the disclosure of KAMs has no immediate reflection in the earnings forecast in the quarter following their disclosure, with their informational content being diluted over the following financial period, impacting the annual earnings forecast.

Abstract This study aimed to assess whether there is a correlation between work-family conflict and perceived social support in Community Health Agents (CHA). Moreover, this is a cross-sectional and correlational study with quantitative design, in which the Multidimensional Work-Family Conflict Scale (MWFCS) and the 2-Way Social Support Scale (2-Way SSS) were used. The participants in this study were 139 CHA workers in four municipalities in the interior of Rio Grande do Sul. Descriptive Statistics, Parametric Statistics, and Pearson Correlation were used to analyze the data. The results between the correlations of the scales were statistically significant (p<0.05) in the factors give emotional support and work family conflict, and receive instrumental support and work family conflict. Therefore, the study allowed us to better understand the relationship between the variables highlighted, and this understanding may support interventions based on Positive Psychology for the CHA.

Resumen El presente estudio tuvo como objetivo evaluar si existe correlación entre conflicto trabajo-familia y apoyo social percibido en trabajadores Agentes Comunitarios de Salud. Además, este es un estudio transversal y correlacional con delineamiento cuantitativo, en que fueron empleadas la Escala Multidimensional de Conflicto Trabajo-Familia (EMCT-F) y la Escala de Percepción de Suporte Social (2-Way SSS). Los participantes de este estudio fueron 139 trabajadores que actúan como agentes comunitarios de salud (ACS) en cuatro municipios del interior de Rio Grande do Sul. Para el análisis de los datos fueron empleadas la Estadística Descriptiva, Estadística Paramétrica y Correlación de Pearson. Los resultados entre las correlaciones de las escalas fueron estadísticamente significativos (p<0,05) en los factores dar apoyo emocional y conflicto familia trabajo y recibir apoyo instrumental y conflicto familia trabajo. Por tanto, el estudio permitió comprender mejor la relación entre las variables destacadas, siendo que ese entendimiento podrá subsidiar intervenciones basadas en la Psicología Positiva para los ACS.

Resumo Este estudo tem como objetivo avaliar se existe correlação entre conflito trabalho-família e suporte social percebido em Agentes Comunitários de Saúde (ACS). Ademais, este é um estudo transversal e correlacional com delineamento quantitativo, em que foram ocupadas a Escala Multidimensional de Conflito Trabalho-Família (EMCT-F) e a Escala de Percepção de Suporte Social (2-Way SSS). Os participantes da pesquisa foram 139 ACS atuantes em quatro municípios do interior do Rio Grande do Sul. Para a análise dos dados, foram utilizadas a Estatística Descritiva, Estatística Paramétrica e Correlação de Pearson. Os resultados entre as correlações das escalas foram estatisticamente significativos (p<0,05) nos fatores dar suporte emocional e conflito família-trabalho, e receber suporte instrumental e conflito família trabalho. Assim, o estudo permitiu compreender melhor a relação entre as variáveis destacadas, sendo que esse entendimento poderá subsidiar intervenções baseadas na Psicologia Positiva para os ACS.

RESUMO CONTEXTO: Os distúrbios evacuatórios são prevalentes na população adulta e uma parcela significativa dos casos pode ter origem a partir de disfunções da musculatura do assoalho pélvico. A manometria anorretal (MAR) é importante ferramenta diagnóstica e pode guiar o tratamento conservador. OBJETIVO: Avaliar a prevalência de disfunção pélvica em pacientes com distúrbios de evacuação por meio de achados clínicos e manométricos e avaliar, usando os mesmos achados, se existem protocolos publicados que possam ser guiados pela MAR. MÉTODOS: Conduziu-se uma análise retrospectiva de um banco de dados prospectivo de 278 manometrias anorretais realizadas para investigação de distúrbios evacuatórios em pacientes do ambulatório de fisiologia anorretal do Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto, de janeiro de 2015 a junho de 2019. Os seguintes parâmetros foram calculados: pressão de repouso (RP), pressão de contração voluntária (PVC), canal anal funcional (CAF), sensibilidade retal (SR) e capacidade retal (CR). As medidas pressóricas e os gráficos manométricos foram revisados para elaboração do diagnóstico e para a proposição dos potenciais procedimentos de fisioterapia pélvica. Para comparação das variáveis contínuas e avaliação da igualdade entre variâncias, utilizou-se a análise de variância (ANOVA) e o teste exato de Fisher, entre os grupos de pacientes com incontinência fecal (IF) e constipação crônica (CC). Resultados com nível de significância menor que 0,05 (P-valor <0,05) foram considerados estatisticamente relevantes. Para análise estatística utilizou-se o programa IBM® SPSS® Statistics, versão 20. RESULTADOS: A idade média dos pacientes foi de 45±22 anos de idade, com predomínio do sexo feminino (64,4%) e economicamente inativo (72,7%). As indicações para a realização do exame foram IF (65,8%) e CC (34,2%). Pacientes com IF apresentaram menores valores de PR (41,9 mmHg x 67,6 mmHg; P<0,001), PCV (85,4 mmHg x 116,0 mmHg; P<0,001) CAF (1,49 cm x 2,42 cm; P<0,001), SR (57,9 mL x 71,5 mL; P=0,044) e CR (146,2 mL x 195,5 mL; P<0,001), quando comparados aos pacientes com CC. Nos pacientes com IF, o principal diagnóstico foi de ausência de canal anal funcional (49,7%). Em pacientes com CI, o principal diagnóstico foi de obstrução da via de saída (54,7%). Para pacientes com IF, o principal protocolo foi a associação do biofeedback anorretal (BFa) com estimulação do nervo tibial (ENT) (57,9%). Já nos pacientes com CC, o protocolo mais indicado foi o de BFa associado à ENT e treinamento com balão retal (54,7%). CONCLUSÃO: Observou-se elevada prevalência de alterações no assoalho pélvico de pacientes com distúrbios evacuatórios. Verificou-se elevado potencial para realização de fisioterapia do assoalho pélvico com base nos achados clínicos e manométricos.

ABSTRACT BACKGROUND: Evacuation disorders are prevalent in the adult population, and a significant portion of cases may originate from pelvic floor muscle dysfunctions. Anorectal manometry (ARM) is an important diagnostic tool and can guide conservative treatment. OBJECTIVE: To evaluate the prevalence of pelvic dysfunction in patients with evacuation disorders through clinical and manometric findings and to evaluate, using the same findings, whether there are published protocols that could be guided by anorectal manometry. METHODS: A retrospective analysis of a prospective database of 278 anorectal manometries performed for the investigation of evacuation disorders in patients seen at the anorectal physiology outpatient clinic of Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto between January 2015 to June 2019 was conducted. The following parameters were calculated: resting pressure (RP), squeeze pressure (SP), high-pressure zone (HPZ), rectal sensitivity (RS) and rectal capacity (RC). The pressure measurements and manometric plots were reviewed to determine the diagnosis and to propose potential pelvic physical therapy procedures. Analysis of variance (ANOVA) and Fisher’s exact test were used to compare the continuous variables and to evaluate the equality of variances between groups of patients with fecal incontinence (FI) and chronic constipation (CC). Results with a significance level lower than 0.05 (P-value <0.05) were considered statistically significant. Statistical analysis was performed using IBM® SPSS® Statistics version 20. RESULTS: The mean age of the sample was 45±22 years, with a predominance of females (64.4%) and economically inactive (72.7%) patients. The indications for exam performance were FI (65.8%) and CC (34.2%). Patients with FI had lower RP (41.9 mmHg x 67.6 mmHg; P<0.001), SP (85.4 mmHg x 116.0 mmHg; P<0.001), HPZ (1.49 cm x 2.42 cm; P<0.001), RS (57.9 mL x 71.5 mL; P=0.044) and RC (146.2 mL x 195.5 mL; P<0.001) compared to those of patients with CC. For patients with FI, the main diagnosis was the absence of a functional anal canal (49.7%). For patients with CC, the main diagnosis was outflow tract obstruction (54.7%). For patients with FI, the main protocol involved a combination of anorectal biofeedback (aBF) with tibial nerve stimulation (TNS) (57.9%). For patients with CC, the most indicated protocol was aBF combined with TNS and rectal balloon training (RBT) (54.7%). CONCLUSION: There was a high prevalence of pelvic floor changes in patients with evacuation disorders. There was a high potential for performing pelvic floor physical therapy based on the clinical and manometric findings.

Resumo Objetivos: A progressão das doenças periodontais ao nível nacional de Portugal e a sua consciencialização pública são de grande interesse, principalmente devido ao elevado impacto da periodontite. O nosso objetivo foi avaliar a progressão da prevalência de doenças periodontais em Portugal e a consciencialização do público correspondente, entre 2004 e 2017, usando dados do GlobalBurden of Disease, Direção Geral de Saúde e Google® Trends. Métodos: Para o período 2004-2017, foram pesquisados dados nacionais portugueses da prevalência de doenças periodontais no Institute forHealth Metricsand Evaluationof Global Burdenof Disease e Direção Geral de Saúde e, para consciencialização do público, ferramenta de comparação do Google® Trends para as palavras em português para “Periodontite”, “Gengivite”, foram utilizadas as tendências “gengivas” e “doença periodontal”. Resultados: A prevalência geral de periodontite aumentou levemente de 11,3% para 11,7%, de acordo com o Global Burdenof Disease. Durante 2004-2017, o termo de pesquisa Google®Trends “Gengivas” foi o mais relevante. Aumentou constantemente ao longo do tempo, enquanto o termo de pesquisa “Doença periodontal” diminuiu, sendo essas tendências de pesquisa significativamente correlacionadas (ρ=-0,670; P=0,009). Além disso, o termo de pesquisa Google®Trends “Gengivite” foi significativamente correlacionado negativamente (ρ=-0,537; P=0,048), ao longo do tempo, com dados do Global Burdenof Disease. Osinternautasportugueses tendem predominantemente a procurar termos não médicos como “Gengivas”em vez de termos mais científicos como “Gengivite”, “Periodontite” ou “Doença periodontal”. Conclusões: Apesar das doenças periodontais em Portugal crescerem continuamente e acima da média mundial, os dados do Google® Trends mostram um aparente analfabetismo médico oral relacionado a doenças periodontais na população portuguesa. No entanto, a consciencialização digital para doenças periodontais aumentou com o tempo.

Abstract Objectives: The progression of periodontal diseases at the Portuguese national level and its public awareness are of great interest, mainly due to the high burden of periodontitis. We aimed to evaluate the progression of the prevalence of periodontal diseases in Portugal and correspondent public awareness, between 2004 and 2017, by using data from the Global Burden of Disease, the Portuguese Directorate-General of Health andGoogleR Trends. Methods: Portuguese national data of periodontal disease prevalence in the period 2004-2017 were searched in the Global Burden of Disease tools of the Institute for Health Metrics and Evaluation and the Portuguese Directorate-General of Health. For data on public awareness, theGoogleR Trends comparison tool was used to study the trends of the Portuguese words for “Periodontitis,” “Gingivitis,” “Gums” and “Periodontal disease.” Results: Overall, the prevalence of periodontitis increased slightly from 11.3% to 11.7%, according to the Global Burden of Disease. During 2004-2017, the GoogleR Trends search term “Gums” was the most relevant. It increased steadily over time while the search term “Periodontal disease” decreased, and these search trends were significantly correlated (ρ=-0.670;P=0.009). Additionally, GoogleR Trends search term “Gingivitis” was significantly negatively correlated (ρ=-0.537;P=0.048), over time, with Global Burden of Disease data. Portuguese netizens predominantly tend to search for non-medical terms like “Gums” over more scientific terms like “Gingivitis,” “Periodontitis” or “Periodontal disease.” Conclusions: Despite periodontal diseases in Portugal being continuously increasing and above the world average, GoogleR Trends data show an apparent oral medical illiteracy related to periodontal diseases in the Portuguese population. However, digital awareness of periodontal diseases increased over time.

Abstract Inflammatory dermatoses are prevalent worldwide, with impacts on the quality of life of patients and their families. The aim of this study was to determine the anti-inflammatory effects of Achyrocline satureioides oily extracts and nanocapsules on the skin using a mouse model of irritant contact dermatitis induced by croton oil, and a skin inflammation model induced by ultraviolet B (UVB) radiation. The mice were treated with 15 mg/ear oily extract (HG-OLAS) or nanocapsules (HG-NCAS) of A. satureioides incorporated into Carbopol® 940 hydrogels. We found that HG-OLAS and HG-NCAS formulations reduced ear edema in croton oil-induced lesions with maximum inhibitions of 54±7% and 74±3%, respectively. HG-OLAS and HG-NCAS formulations decreased ear edema induced by UVB radiation (0.5 J/cm2), with maximum inhibitions of 68±6% and 76±2% compared to the UVB radiation group, respectively. HG-OLAS and HG-NCAS modulated myeloperoxidase (MPO) activity after croton oil induction. Furthermore, croton oil and UVB radiation for 6 and 24 h, respectively, stimulated polymorphonuclear cells infiltration. The topical treatments reduced inflammatory processes, as shown by histological analysis. Together, the data suggest that topical application of A. satureioides oily extracts and nanocapsules produced antiedematogenic and anti-inflammatory effects. They constitute a compelling alternative for treatment of skin injuries.

ABSTRACT. Filter cake has been one of the most widely used waste products as a source of organic matter in the production of biofertilizers. However, sanitized sewage sludge is a recommended alternative for agricultural use because of environmental issues. Studies that examine the use of this particular class of fertilizer are needed. The objective of this work was to evaluate the efficiency of sewage sludge and filter cake as sources of organic matter in the composition of pelletized biofertilizers for soybean production. The experimental design was a randomized block design in a 2 x 4 + 2 factorial, which includes two sources of organic matter (sanitized sewage sludge and filter cake) and four levels of nitrogen (50, 75, 100, and 125%) relative to the recommended dose of phosphorus pentoxide compared with the mineral fertilizer. The use of organomineral fertilizer with the formulation of 75% sewage sludge showed greater growth for aerial plant parts. Biofertilizers formulated with sewage sludge and filter cake can replace mineral fertilizer and increase soybean growth. Quantitative changes in peroxidase, catalase and urease activity, as well as lipid peroxidation, were observed following the use of biofertilizers.

Abstract Purpose To evaluate the gene expression of peroxisome proliferator activated receptors gamma (PPARG) in colorectal tumors and to correlate this data with clinical variables of the patients. Methods We analyzed the gene expression of PPARG in 50 samples of colorectal tumors using real-time reverse transcription polymerase chain reaction, and 20 adjacent normal tissue samples as control. The results of these quantifications were correlated with the respective patients’ medical records’ clinical information. Results PPARG expression was not different in the tumor tissue compared to the control tissue. Patients older than 60 years, histological type with mucinous differentiation, more advanced staging at the time of diagnosis, and patients who evolved with recurrence of the disease or death did not present higher PPARG expression. Conclusion Expression of PPARGD was not associated with worse prognosis.

Abstract This retrospective study evaluated the influence of known risk factors on nonsurgical periodontal treatment (NSPT) response using a pocket depth fine-tuning multilevel linear model (MLM). Overall, 37 patients (24 males and 13 females) with moderate-to-severe chronic periodontitis underwent NSPT. Follow-up visits at 3, 6, and 12 months included measurements of several clinical periodontal parameters. Data were sourced from a previously reported database. In a total of 1416 initially affected sites (baseline PD ≥ 4 mm) on 536 teeth, probing depth (PD) and clinical attachment loss (CAL) reductions after NSPT were evaluated against known risk factors at 3 hierarchical levels (patient, tooth, and site). For each post-treatment follow-up, the variance component models fitted to evaluate the 3-level variance of PD and CAL decrease revealed that all levels contributed significantly to the overall variance (p < 0.001). Patients who underwent NSPT and were continually monitored had curative results. All 3 hierarchical levels included risk factors influencing the degree of PD and CAL reduction. Specifically, the type of tooth, surfaces involved, and tooth mobility site-level risk factors had the strongest impact on these reductions and were highly relevant for the success of NSPT.

Resumo Este artigo apresenta a primeira identificação do cauixi em cerâmica arqueológica na região de Lagoa Santa, Minas Gerais. Trata-se de um estudo zooarqueológico que aborda as escolhas pretéritas feitas pelos ameríndios no que tange à presença de espículas de esponjas dulcícolas no processo de produção cerâmica. A partir dos elementos faunísticos detectados na coleção do sítio Vereda III, juntamente com informações obtidas de registros etnográficos e de pesquisas arqueológicas que tratam da presença do cauixi em cerâmica, é discutido se a presença desse elemento no material é fruto de coleta de esponjas dulcícolas, preparo e inclusão na pasta, ou se ele advém da exploração de depósitos sedimentares com espículas. O trabalho aponta para uma necessária revisão do material cerâmico arqueológico da tradição Aratu-Sapucaí em Minas Gerais, em que a identificação do cauixi e a sua proveniência devem ser consideradas.

Abstract This article presents the first identification of cauixi sponge material in archaeological pottery from the Lagoa Santa region, Minas Gerais, Brazil. This zooarchaeological study addresses whether the presence of spicules of freshwater sponges in this pottery was a conscious choice on behalf of ancient potters. Based on faunal elements detected in the collection of the Vereda III site and information obtained from ethnographic records and archaeological research on the presence of cauixi in pottery, we discuss whetherits presence in the material results from the inclusion of processed freshwater sponges in the clay or if it derives from the exploitation of sedimentary deposits with spicules. As one of the outcomes, this articlepoints to a necessary revision of the archaeological pottery material of the Aratu-Sapucaí tradition in Minas Gerais where the identification of cauixi and its origin should both be considered.

RESUMO O filo Porifera, representado no Estado do Mato Grosso do Sul somente por esponjas de água doce, conta atualmente a nível mundial com cerca de 230 espécies em ambientes dulcícolas, das quais 53 são conhecidas para o Brasil e 11 para o Estado. Destacam-se os depósitos fósseis de espículas (espongilitos) produzidos por 6 espécies dessas esponjas em ambientes lênticos quaternários de água doce em todo Estado, representando um importante recurso mineral. Um registro novo é aqui produzido para o Mato Grosso do Sul, o de Sterrastrolepis brasiliensis. Os Biomas Pantanal, Cerrado, Chaco e Mata Atlântica não foram até agora levantados para essa fauna aquática no Estado. Nesse sentido deve ser concedida prioridade ao Pantanal, considerado atualmente dos biomas mais ameaçados do planeta.

ABSTRACT The phylum Porifera, represented in the state of Mato Grosso do Sul (MS) solely by freshwater sponges, counts worldwide with around 230 species in freshwater habitats, of which 53 are presently known for Brazil and 11 for the MS. Remarkable is the fossil deposits of spicules (spongillites) produced by 6 species of these sponges in lentic quaternary freshwater habitats throughout the State and as such an important mineral resource. A new record is now produced for Mato Grosso do Sul, that of Sterrastrolepis brasiliensis. The Pantanal, Cerrado, Mata Atlântica and Chaco Biomes have not up to now been surveyed for this aquatic fauna in the State. Priority should be focused into the Pantanal, presently considered one of the world most endangered biomes.

RESUMO É apresentado um levantamento das espécies de Cerambycidae, Disteniidae e Vesperidae que ocorrem no estado do Mato Grosso do Sul, Brasil. Os dados foram baseados na literatura e no acervo da coleção do Museu Nacional, Universidade Federal do Rio de Janeiro. São registradas 229 espécies de Cerambycidae, distribuídas em cinco subfamílias. São registradas duas espécies de Disteniidae e duas de Vesperidae.

ABSTRACT A survey of the Cerambycidae, Disteniidae and Vesperidae species recorded from Mato Grosso do Sul state, Brazil, is presented. The data were based on literature and in the collection of the Museu Nacional, Universidade Federal do Rio de Janeiro. Two hundred and twenty nine species are registered to Cerambycidae, distributed in five subfamilies. Two species of Disteniidae and two of Vesperidae, are registered.

RESUMO O câncer colorretal é a principal neoplasia maligna do trato gastrointestinal. Um melhor entendimento dos processos moleculares e celulares é necessário para o desenvolvimento de estratégias que permitam um diagnóstico precoce e um tratamento mais eficaz. Modelos que utilizam roedores são rápidos, reprodutíveis e permitem o estudo da sequencia adenoma-carcinoma de forma similar a encontrada em humanos. O objetivo desse manuscrito é revisar os principais modelos de carcinogênese química e os métodos mais usuais para avaliação dos resultados.

ABSTRACT Colorectal cancer is the leading cause of malignancy of the gastrointestinal tract. A better understanding of the molecular and cellular changes that lead to the disease is necessary to develop early diagnosis and optimal treatment modalities. Rodent models are rapid, reproducible and exhibit an adenoma-carcinoma sequence similar to that found in humans. The objective of this manuscript is to review the most common chemical carcinogens used to induce experimental tumors and the usual methods of evaluation.

PURPOSE: To describe a novel securing device for loop colostomies, developed in our institution and report our 10-year experience. METHODS: The T-shaped support device was used in all patients who required loop colostomy and who were at an increased risk of stoma withdrawal. The device was removed on the fifth postoperative day in all patients. An analysis from a prospective database regarding early postoperative complication, from 209 patients, was conducted between 2003 and 2013. RESULTS: Bleeding, peristomal skin problems, surgical site infection, stomal ischemia/necrosis, stenosis, obstruction, retraction and early withdrawal of the stoma were not noted in all cases. Thirteen patients (6%) reported mild discomfort on the site of the skin suture. Removal of the instrument was fast and easy, with the advantage of keeping the colostomy bag. CONCLUSION: The T-shaped bridge device successfully prevented stoma withdrawal in all subjects. The device was safe and well accepted, with minor complications.

PURPOSE: In this paper we report the oncological outcomes from clinical series of patients with rectal cancer submitted to local excision after neoadjuvant therapy and discuss the indications for local excision in partial clinical responders. METHODS: We analysed a prospective database of 39 patients submitted to a transanal endoscopic operation for rectal cancer after neoadjuvant chemoradiation between 2006 and 2015, comparing clinical and pathological variables, perioperative complications, recurrence rate and overall survival. RESULTS: We obtained 15.4% ypT0, 17.9% ypT1, 35.9% ypT2 and 28.2% ypT3. After a median follow-up of 24 months, tumoral recurrence was observed in 4 patients, one of them with isolated pulmonary metastasis. R0 resection was achieved in 79.5%, and postoperative complications were observed in 30.2% patients and no perioperative mortality occur. Compromise surgical margins do not affect recurrence rate, and 94.9% of patients are alive nowadays. CONCLUSION: Local excision could be associated with low recurrence rate and good overall survival. Short hospitalization time and low level of serious complications observed could be an interesting option for patients who would not tolerate a radical procedure or for those who declined a total mesorectal excision. A strict long-term follow-up must be warranted to detect early tumoral recurrence.