Resumo Os técnicos em citopatologia são fundamentais para o rastreamento do câncer de colo do útero, porém existem lacunas na sua formação. Nesta revisão de literatura, com abordagem qualitativa, realizada na Biblioteca Virtual em Saúde e na SciELO, sem recorte temporal, descrevemos o histórico das políticas públicas de combate ao câncer de colo de útero, relacionando-o à história da educação profissional técnica em citopatologia, analisando as conexões entre tais sequências de eventos. Numa perspectiva histórica, a educação profissional em anatomia patológica se deu principalmente pela formação em serviço, porém o campo da formação técnica em citopatologia destoa desse modelo. Esforços diversos para estruturar os currículos na área e reduzir as discrepâncias nessa formação foram realizados. Contudo, disputas entre interesses político-econômicos, marcando a divisão técnica do trabalho no país, somadas a embates corporativos no trabalho em citopatologia, e o descompasso entre ações de educação e de rastreamento impediram a materialização efetiva desses esforços. A demanda pela incorporação de novas tecnologias acentua ainda mais a fragilidade na formação da categoria. Somente com ações governamentais concretas de formação e de regulamentação profissional será possível transformar esse cenário, favorecendo o desenvolvimento e a ampliação das campanhas de detecção precoce do câncer. útero literatura qualitativa SciELO temporal relacionandoo relacionando eventos histórica serviço modelo realizados Contudo políticoeconômicos, políticoeconômicos político econômicos, econômicos político-econômicos país esforços categoria cenário

Resumen Los técnicos en citopatología son fundamentales para el rastreo del cáncer de cuello uterino, pero existen lagunas en su formación. En esta revisión bibliográfica, con abordaje cualitativo, realizada en la Biblioteca Virtual en Salud y en SciELO, sin marco temporal, se describe la historia de las políticas públicas de combate al cáncer de cuello uterino, relacionándola con la historia de la formación técnico-profesional en citopatología, analizando las conexiones entre tales secuencias de eventos. Desde una perspectiva histórica, la formación profesional en anatomía patológica se basó principalmente en la formación en servicio, pero el campo de la formación técnica en citopatología difiere de este modelo. Se han hecho varios esfuerzos para estructurar los planes de estudio en el área y reducir las discrepancias en esta formación. Sin embargo, las disputas entre intereses políticos y económicos, que marcan la división técnica del trabajo en el país, sumadas a los enfrentamientos empresariales en el trabajo de citopatología, y la discrepancia entre las acciones de educación y de rastreo impidieron la materialización efectiva de estos esfuerzos. La demanda por la incorporación de nuevas tecnologías acentúa aún más la fragilidad en la formación de la categoría. Solo con acciones gubernamentales concretas de capacitación y regulación profesional será posible transformar este escenario, favoreciendo el desarrollo y la expansión de las campañas de detección temprana del cáncer en Brasil. uterino bibliográfica cualitativo SciELO temporal técnicoprofesional técnico eventos histórica servicio modelo embargo económicos país categoría escenario Brasil

Abstract Cytopathology technicians are fundamental for cervical cancer screening, but there are gaps in their training. In this literature review, with a qualitative approach, carried out in the Virtual Health Library and in SciELO, without temporal clipping, we describe the history of public policies to combat cervical cancer, relating it to the history of technical professional education in cytopathology, analyzing the connections between such sequences of events. In a historical perspective, professional education in pathological anatomy was mainly through in-service training, but the field of technical training in cytopathology differs from this model. Various efforts have been made to structure curricula in the area and reduce discrepancies in this training. However, disputes between political and economic interests, marking the technical division of labor in the country, added to corporate clashes in the work on cytopathology, and the mismatch between education and screening actions prevented the effective materialization of these efforts. The demand for the incorporation of new technologies further accentuates the fragility in the formation of the category. Only with concrete government actions of training and professional regulation will it be possible to transform this scenario, favoring the development and expansion of campaigns for early detection of cancer in Brazil. review approach SciELO clipping events perspective inservice service model However interests country category scenario Brazil

BACKGROUND The Memórias do Instituto Oswaldo Cruz (MIOC) is one of the first scientific journals created in Brazil and currently one of the most important biomedical journals in South America. Knowledge of the main themes disseminated over time and its main contributors can contribute towards a better understanding of its trajectory and future. OBJECTIVES Map the journal’s scientific publication between 1909 and 2020. METHODS Data from three scientific databases was combined, alongside bibliometrics and network analysis to analyse publication records between 1909 and 2020. FINDINGS Publications increased substantially since the 1980s. The main publishing organisations are Brazilian. Excluding Brazil, the main publishing countries are the USA, Argentina, and Colombia. During the entire investigated period, the main themes refer to Chagas disease, schistosomiasis, and Leishmaniasis. During some periods, publications followed disease outbreaks in Brazil (e.g., dengue fever and yellow fever). MAIN CONCLUSIONS Since its foundation in 1909, the MIOC has focused on infectious and parasitic diseases. The editorial changes implemented from the 1980s onwards led MIOC to a relevant growth concerning annual publications and its transformation into an important communication vehicle for researchers from several Brazilian organisations besides Fiocruz, as well as organisations from other countries, especially within Latin America.

SUMMARY: This study aimed to develop models that reproduce histological slide images and evaluate them with blind and sighted students from an inclusion perspective. A questionnaire with questions about the ideal characteristics of a model was answered by visually impaired (VI) students. Based on the responses and optical microscopy images from histological atlases, nine models were constructed with standardized materials. The models were tested at different times with VI students and with students who see. Our results indicate that morphology teaching, according to the students themselves, should make use of extra resources, such as models. The ideal characteristics for model efficiency as a teaching tool were representative textures and reliefs. The models built were evaluated by blind students in Spain and sighted students in Brazil because, from an inclusive perspective, it is ideal that the same material can meet the demands of all types of students. The use of the developed models enhanced learning in both groups, even when combined with microscopes for sighted students. According to student opinions, the use of relief models can represent an important pedagogical strategy used to teach morphological. The importance of developing that materials was also highlighted from an inclusion perspective, as these materials can be used in mixed classes, all students together, in cooperative learning. This study aids morphological subject teachers who teach visually impaired students to know where to start on the path to an inclusive and pedagogically coherent learning process.

RESUMEN: Este estudio tuvo como objetivo desarrollar modelos que reproduzcan imágenes histológicas de diapositivas y las evalúen con estudiantes ciegos y videntes desde una perspectiva de inclusión. Los estudiantes no videntes respondieron un cuestionario con preguntas sobre las características ideales de un modelo. En base a las respuestas y las imágenes de microscopía óptica de los atlas histológicos, se construyeron nueve modelos con materiales estandarizados. Los modelos fueron probados en diferentes momentos con estudiantes no videntes y con estudiantes videntes. Nuestros resultados indican que en la enseñanza de la morfología, según los propios estudiantes, se debe hacer uso de recursos adicionales tal como los modelos. Las características ideales para la eficiencia del modelo como herramienta de enseñanza fueron las texturas y relieves representativos. Los modelos construidos fueron evaluados por estudiantes ciegos en España y estudiantes videntes en Brasil. Desde una perspectiva inclusiva, es ideal que un mismo material pueda satisfacer las demandas de todo tipo de estudiantes. El uso de los modelos desarrollados mejoró el aprendizaje en ambos grupos, incluso cuando se combinó con microscopios para estudiantes videntes. Según las opiniones de los estudiantes, el uso de modelos en relieve puede representar una importante estrategia pedagógica utilizada en la enseñanza de la morfología. También se destacó la importancia de desarrollar esos materiales desde una perspectiva de inclusión, ya que estos materiales pueden ser utilizados en clases mixtas, todos los estudiantes juntos, en aprendizaje cooperativo. Este estudio ayuda a los profesores de asignaturas morfológicas que enseñan a los estudiantes con discapacidad visual a conocer la vía hacia un proceso de aprendizaje inclusivo y pedagógicamente coherente.

Resumo No Brasil, a malacocultura é desenvolvida principalmente no estado de Santa Catarina, seguida por São Paulo e Rio de Janeiro. No curso do desenvolvimento das atividades da maricultura brasileira, a legislação se adaptou aos requisitos sanitários necessários à comercialização de bivalves. No entanto, o monitoramento de ficotoxinas é um desafio, devido a métodos de referência frequentemente caros. Nesse contexto, o objetivo deste estudo foi avaliar o uso de métodos ecotoxicológicos e bioanalíticos alternativos usando a Artemia franciscana (artemia). Os resultados confirmam que, embora as correlações entre o ensaio de referência em camundongos e os ensaios com artemia não sejam altas, o ensaio alternativo com artemia pode ser incorporado aos programas de monitoramento de ficotoxinas, pois os extratos metanólicos do hepatopâncreas de mexilhões (Perna perna) contendo DSP resultaram em altas taxas de letalidade. Portanto, estudos adicionais de ajustes metodológicos e a inclusão de outros modelos enzimáticos e toxicológicos são necessários para avaliar essas diferenças, e são encorajadas associações entre métodos ecotoxicológicos como métodos de alarme precoce.

Abstract In Brazil, malacoculture is developed mainly in the state of Santa Catarina, followed by São Paulo and Rio de Janeiro. In the course of the development of Brazilian mariculture, legislation has addressed the sanitary requirements necessary for bivalve commercialization. However, monitoring phycotoxins is a challenge, due to often costly reference methods. In this context, this study evaluated the use of alternative ecotoxicological and bioanalytical methods using Artemia franciscana (brine shrimp) lethality assessments. The results confirm that, although correlations between the reference mouse assay and the brine shrimp assays were not high, the alternative brine shrimp assay may be incorporated into phycotoxin monitoring programs, as hepatopancreas methanolic extracts of mussel (Perna perna) containing DSP resulted in high lethality rates. Therefore, further methodological adjustment studies and the inclusion of other enzymatic and toxicological models are required to further assess these differences, and associations between ecotoxicological methods as early-alarm methods are encouraged.

This article describes a Problem-Based Learning (PBL) experience that taught organophosphorus pesticides chemistry, its human health effects and acetylcholinesterase assay to secondary students. The teaching process was based on a real intoxication case and ended with students' activities report presentation. The apparent lack of teacher reference and inexistence of a curriculum based on a strict textbook in which PBL is based on leads inexperienced students to insecurity and the idea that teachers are not doing there jobs. One way to minimize this situation is to use real cases in other to interest students as stakeholders of central problem solution.