Abstract Enteroparasites are an important public health problem and the treatment seeks to cure and reduce transmission. The aim of this study was to evaluate the therapeutic efficacy of anthelmintic treatment in individuals living in a rural community area in Camamu, Bahia, Brazil. The parasitological diagnosis was performed by spontaneous sedimentation, Baermann-Moraes and Agar Plate Culture methods. A total of 212 individuals were evaluated. The most frequent helminth was Trichuris trichiura, 24.5% (52/212), followed by Ascaris lumbricoides, 21.2% (45/212), hookworms, 16.5% (35/212), and S. stercoralis, 4.7% (10/212). In the anthelmintic treatment follow up, T. trichiura infection presented the lowest parasitological cure rate, only 60.6% (20/33). Hookworm, Ascaris lumbricoides and Strongyloides stercoralis infections demonstrated cure rates of 70.5 (12/17), 78.1 (25/32) and 100% (5/5), respectively. Individuals who remained infected underwent a new drug therapy. The second parasitological cure rate for T. trichiura was 38.5% (5/13), and 66.7% (2/3) and 75% (3/4) for hookworms and Ascaris lumbricoides, respectively. Trichuris trichiura infection presented the lowest parasitological cure rate at this second evaluation. This reinforces the need to perform a follow-up of all treated individuals. The possibility of drug resistance denotes the necessity for studies to clarify the mechanisms and to evaluate new therapeutic approaches.

A suscetibilidade à quimioterapia com o benzonidazol, de 5 clones isolados da cepa 21SF (biodema Tipo II, T. cruzi II), foi investigada. Camundongos suíços foram infectados com a cepa parental e com cada clone e submetidos à quimioterapia com benzonidazol (100mg/k/dia durante 90 dias). Os índices de cura foram avaliados pelos testes de cura parasitológicos. A sorologia foi avaliada para os animais tratados e (de negativo a 1: 640) e para os controles não tratados( 1:160 a 1:640). Os índices de cura variaram de 30% a 100% para os 5 clones sendo de 25% para a cepa parental. Os resultados sugerem que a variabilidade de resposta ao tratamento das populações clonais das cepas Trypanosoma cruzi II é responsável pela grande variação na resposta à quimioterapia com benzonidazol e nifurtimox das cepas deste biodema.

Susceptibility to chemotherapy with benznidazole was investigated of 5 clones isolated from the 21 SF strain (biodeme Type II, Trypanosoma cruzi II). Swiss mice were infected with the parental strain for each clone and submitted to chemotherapy with benznidazole (100mg/kg/day during 90 days). Treatment determined negativity of the parasitemia. Cure rates were evaluated by parasitological cure tests. Serology was evaluated for treated animals (titers from negative to 1:640) and untreated controls (1:160 to 1:640). Cure rates varied from 30 to 100% for the 5 clones, and were 25% for the parental strain. Results suggested that the variability of response to treatment of the clonal populations of Trypanosoma cruzi II strains is responsible for the high variation in the response to chemotherapy with benznidazole and nifurtimox by strains of this biodeme.

A grande maioria dos estudos fotoluminescentes foram realizados com materiais cristalinos, cuja emissão ocorre em temperaturas criogênicas, limitando a aplicação destes materiais. Por sua vez, determinados sólidos com alta densidade de defeitos (amorfos), como titanatos, tungstatos, zirconatos, entre outros, apresentam fotoluminescência à temperatura ambiente, semelhante à do silício amorfo. Essa descoberta levou à necessidade de se desenvolver novos modelos para explicar o comportamento desses materiais, mais adequados ao estudo desses materiais. Esta revisão tem como objetivo explicar os resultados de fotoluminescência, utilizando uma abordagem teórico-experimental, com base nas recentes pesquisas desta propriedade em óxidos amorfos.

The majority of the studies about photoluminescence had been carried out with crystalline materials, whose emission occurs at cryogenic temperatures, limiting the application of these materials. In turn, some amorphous solids, as titanates, tungstates, zirconates, among others, present photoluminescence at room temperature, seemed with silicon. This discovery led to the necessity of developing new models to explain the behavior of these materials. This revision intends to elucidate the results on photoluminescence, using a theoretical-experimental treatment, on the basis of the recent researches of this property in amorphous oxides.

A descriptive study of serum iron value behavior and hemoglobin in blood donors in the blood extraction bank at Manuel Ascunce Domenech provincial hospital of Camagüey within a period of six months (from january 1 st to june 30, 1999) was carried out. The universe was composed of 800 voluntary blood donors, of which, a ramdomized representative sample formed 200 of these donors was obtained . They were determined the value serum iron and hemoglobin, with the aim of correlating them. Serum iron behavior was evaluated as to sex and age. A relationship among serum values and hemoglobin with the clinical manifestations found was established, and finally the relationship among serum iron values and hemoglobin was determined with the number of donation made in almost one year. When processing data, it was concluded that 100 % of donors studied, presented low values of serum iron which manifested clinical symptoms , 10 % of them and 88 % had normal hemoglobin, existing and inverse relationship among the increasing of previous donations during one years and serum iron values and hemoglobin.

Se realizó un estudio descriptivo del comportamiento de los valores del hierro sérico y la hemoglobina en donantes de sangre en el banco de extracciones de sangre del Hospital Clínico Quirúrgico Docente Manuel Ascunce Domenech, de Camagüey, en un período de seis meses (entre el 1ro de enero y el 30 de junio de 1999). El universo estuvo constituido por 800 donantes de sangre voluntarios, de los cuales se obtuvo una muestra aleatoria representativa conformada por 200 de estos donantes, a los que se les determinó el valor del hierro sérico y la hemoglobina con el objetivo de correlacionarlos. Se evaluó el comportamiento del hierro sérico según el sexo y la edad y se estableció una relación entre los valores del hierro sérico y la hemoglobina con las manifestaciones clínicas encontradas y finalmente se estableció la relación entre el hierro sérico y la hemoglobina con el número de donaciones hechas en un período anterior de un año. Al procesar los datos se concluyó que el 100 % de los donantes estudiados presentaron valores bajos del hierro sérico que manifestaron síntomas clínicos en un 10 % de ellos y el 88 % presentó hemoglobina normal, al existir una relación inversa entre el aumento de las donaciones previas en un año y los valores del hierro sérico y la hemoglobina.