ABSTRACT Nowadays, the problem of maintaining and strengthening the health of the young generation has arisen. In the media, we often hear calls that it is necessary to be healthy, but the real situation suggests the opposite - the health of young people is deteriorating, exacerbated by cardiovascular pathology and other chronic and infectious diseases. In addition, the current level of scientific and technological development, urbanization, comfort is the cause of chronic “motor hunger”. The article is devoted to the analysis of the physical and physiological needs of students in the process of classes in physical culture and sports. The author notes a decrease in indicators of the state of health, the level of physical development and preparedness of students due to the unformed form of the need for physical education and because of the low level of motivation. It is concluded that the need for systematic studies should be considered as the daily need of students to increase physical activity, improve life and relaxation, and in order to act on this need in order to attract students to systematic classes, it is necessary to know the dialectic, the whole process of its formation, starting from intuitive to the end of the unconscious emergence of need, ending with a deliberate action to satisfy it.

RESUMEN Hasta la fecha, ha surgido el problema de mantener y fortalecer la salud de la generación joven. En los medios de comunicación, a menudo escuchamos llamadas de que es necesario estar sano, pero la situación real sugiere lo contrario: la salud de los jóvenes se está deteriorando, exacerbada por la patología cardiovascular y otras enfermedades crónicas e infecciosas. Además, el nivel actual de desarrollo científico y tecnológico, urbanización, comodidad es la causa del "hambre motora" crónica. El artículo está dedicado al análisis de las necesidades físicas y fisiológicas de los estudiantes en el proceso de clases en cultura física y deportes. El autor observa una disminución en los indicadores del estado de salud, el nivel de desarrollo físico y la preparación de los estudiantes debido a la forma no formalizada de la necesidad de educación física y al bajo nivel de motivación. Se concluye que la necesidad de estudios sistemáticos debe considerarse como la necesidad diaria de los estudiantes de aumentar la actividad física, mejorar la vida y la relajación, y para actuar sobre esta necesidad y atraer a los estudiantes a clases sistemáticas, es necesario saber la dialéctica, todo el proceso de su formación, que comienza desde la intuición hasta el final de la emergencia inconsciente de la necesidad, terminando con una acción deliberada para satisfacerla.

ABSTRACT At the moment, health, as well as a healthy lifestyle, is becoming one of the most pressing problems among young people. During the training, students receive not only professional skills, but during this period of their life, their social status is formed. In this article, the author focuses on the problem of forming skills for a healthy lifestyle and suggests the use of a valeological approach to solve this problem in higher education. In addition, the author gives recommendations on how it is possible to introduce this approach into the higher education program in the process of teaching the discipline "Physical Culture and Sports".

RESUMEN Por el momento, la salud, así como un estilo de vida saludable, se están convirtiendo en uno de los problemas más acuciantes entre los jóvenes. Durante la capacitación, los estudiantes reciben no solo habilidades profesionales, sino que, durante este período de su vida, se forma su estatus social. En este artículo, el autor se centra en el problema de formar habilidades para un estilo de vida saludable y sugiere el uso de un enfoque valorativo para resolver este problema en la educación superior. Además, el autor ofrece recomendaciones sobre cómo es posible introducir este enfoque en el programa de educación superior en el proceso de enseñanza de la disciplina "Cultura física y deporte".

Pure C-phycocyanin (C-PC) was isolated from Arthronema africanumto evaluate its potential antitumor effects in vivo and in vitro. Experimental myeloid Graffi tumor in hamsters was used as a model. The cell proliferation assay showed that C-PC treatment, at concentration of 100 µg mL-1 for 24 h, significantly inhibited the growth of Graffi tumor cells (51.4% viability). Agarose gel electrophoresis of the genomic DNA of treated cells displayed time-and concentration-dependent fragmentation pattern, typical for apoptosis. Apoptotic process was related to the increase in cellular manganese and copper/zinc superoxide dismutases and glutathione reductase activities, coupled with a low catalase activity. In vivo C-PC administration (5.0 mg kg-1 body weight) suppressed the tumor transplantability and growth, while the mean survival time of the tumor-bearing hamsters was increased. The results revealed promising antitumor activities of A. africanum C-PC and suggested the potential of this natural biliprotein pigment for future pharmacological and medical applications. The study provided new data on the mechanism of the C-PC induced apoptosis in which the imbalance of antioxidant enzymes that favoured hydrogen peroxide accumulation might play a leading role.